Gene DDB_G0293258 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily DdisMTMR1-like
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP030_AA protein Get Run
DdisP030_AA_628-1188 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0040695 (Phosphotyrosine protein) phosphatases II 627-1184 2.7e-109 359.3 In-house 5-385 (388) alignment 
Range on Protein: 627-1184
Range on HMM: 5-385/388.0
INGWLIYNSEREYKRMNIKAGsGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTGSRCIDDEL
..|| .|. .||.||....    ||||..|.... |.||| |.||| .|.|..|..|. |||||||||||..|| || ...|.|||||||..||...|| 
eegwslydilrelkrlglgld.lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledek

LIKQISSPTIiqqpqsqqqssspppsfinyssttstnstpnlnqinnindnfkslnnsgnsivfnkrqsyisnslsnlesslvsnnnnnnsninnnnnnn
|...| . .                                                                                           
lleailkllp..........................................................................................

nVEKILNLLDARPKVNAMSNKAfMGAGFENVStFYSCCNIDFLNIGNIHVMRDSYEKLKSTCiDSLGGIKEIKNSNNtnqdnnnnnfnlnnsnsnnnnnn
   . | ..|.|||.||. |.| .| |.|| . .|..... |||| ||||.|.|. || . | ... .. .. .. .                       
.nlskllivdlrpklnalanra.lgggvened.aypnaeliflnipnihvvreslqklldac.lnvpdslnllslle.......................

tnvnsdnnnnnnivrseseeelssfllenetpissihssdiidnnegyngtnikwfegieSSRWFDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRT
                                                            .|.|.|.| |||.... ||. .... .|||.|||||||||
............................................................esgwldliklilelavlivklldlgnssvlvhcsdgwdrt

PQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRIGQGD-SKHLDERSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEiLVNGLYSNRFGTFLYN
.||||.....|||||||||||.|||||||| ||||| ||.|... ... .|.||||..|..||.... ||   ||||...|.  |.  |||.||||||.|
sqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlf.LadhlyscrfgtFlfn

TVREREINKVQLETASIWSLILSNYSFYINQNYTRMDK-VLIPSIAIPYFSLWKDYYLKY
. .|| ...|.  | |.||..||. | ..|..| ..   ||.||. .. . || .|||..
sekerlelsvsertlslwsyllsrkseflnplYdpsslevllpslsvldlllWleyylrw
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 910-1184 1e-87 286.9 In-house 140-402 (404) alignment 
Range on Protein: 910-1184
Range on HMM: 140-402/404.0
NNNFNLNNSNSNNNNNNTNVNSDNNNNN-------------------NivrseseeelssfllenetpissihssdiidnnegyngtNIKWFEGIESSRW
.|. . .. .. ....|..... | .|                    .                                       . .|.. .|||||
ansakgagyedisryenceieflnienihelreslkklkkavnsiiek.......................................eknwlselessrW

FDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRIGQGDSKHLDERSPVFVQFIECVYH
.|||.|.|.|| ||||.|.|...|||.|||||||||.||||.|...|||||||.||||||||||||.|||||..|||| ..|. |||||.|.|||.|||.
ldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyq

IMEQFKNYFEFNSQVLVEILvNGLYSNRFGTFLYNTVREREINKVQLETASIWSLILSNYSFYINQNYTRMD----KVLIPSI-----AIPYFSLWKDYY
...||...||||...|..|| . |||.|||||||.. .||. |... || |.|.|. .| | |.|..|   .    .    |       |  ..||..||
ltkqfptsFeFnekflikil.dalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWseyy

LKY
|..
lrw
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 625-886 1.1e-84 277.0 In-house 11-283 (404) alignment 
Range on Protein: 625-886
Range on HMM: 11-283/404.0
DKINGWLIYNSEREYKRMNIKAGSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTGSRCIDD
   .|||||..|.||||..||. | ||||.||.|...||.||||.||||.|.|..|..|. ||||||||||||.|.|...||||.||||||||.||...|
vledgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksrseed

ELLIKQISS------PTIIQQPQSQQQSSSPPPSFINYS----STTSTNSTPNLNQINNINDNFKSLNNSGNSIVFNkrqsyISNSLSNLESS-------
|.||..|..      ...|.. .........  ....|.    .........|...|.......|.|... |||. .     ..|.||.||||       
Eklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiek.....eknwlselessrWldhik

LVSNNNNNNSNINNNNNNNNVEKILNLLDARPKVNAMSnKAFMGAGFENVSTFYSCCNIDFLNIGNIHVMRDSYEKLKS
|.................... ......|........| ...... ......|........|..|.....|..... ||
lllegskriveliekekssvlvhcsdgwDrtsqlssls.qllldpyyrtiegFivliekewlsfGhkfaqRigqtteks
subfamily_MTMR1_pd Subfamily MTMR1 978-1184 7e-84 274.4 In-house 178-386 (389) alignment 
Range on Protein: 978-1184
Range on HMM: 178-386/389.0
NIKWFEGIESSRWFDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRIGQGDSKH-LDE
. ||.  .||..|..|| |||.|...|||..... ||||.||||||||| || |..|..||.||||.|||.|||||||| |||||..|.|.||...  .|
dkkwlsalestkWlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdae

RSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEILvNGLYSNRFGTFLYNTVREREINKVQLETASIWSLILSNYSFYINQNYTRM--DKVLIPSIAIPYF
|||||.|||.||. ...|| . ||||.. |. .| . ||| .|||||.|. .||. .||. .| |.|| . |. . ..|..|...  .|||.| ...   
rsPvFlqfiDcvwqltrqfptAFefneefLitll.dhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrl

SLWKDYYLKY
 |||.|||..
elWkeyylrw
subfamily_MTMR3_pd Subfamily MTMR3 978-1183 4.1e-73 239.6 In-house 235-441 (442) alignment 
Range on Protein: 978-1183
Range on HMM: 235-441/442.0
NIKWFEGIESSRWFDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRIGQG-DSKHLDE
...|.  .|. .|. ..  .|| ....||...|.  .||.|||||||||.|. ... ..||||||||||| ||.|.|||.|||||.||.|.| .... .|
esnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddane

RSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEiLVNGLYSNRFGTFLYNTVREREINKVQLETASIWSLILSNYSFYINQNYTR-MDKVLIPSIAIPYFS
|.|||.|....|... .||   ||||.  ||  ||.  ||  ||||| |. .||| .||. .| |.|||. ..   | |. |..  ..||.|.. .  ..
rcPvflqwldavhqlqrqfPtsfefneaflvk.lvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekteavllpavsvrelk

LWKDYYLK
||.. ||.
lwsevyle
subfamily_MTMR6_pd Subfamily MTMR6 967-1184 6.8e-69 225.0 In-house 178-395 (397) alignment 
Range on Protein: 967-1184
Range on HMM: 178-395/397.0
IIDNNEGYNGTNIKWFEGIESSRWFDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRI
... .|  . .  ....|.||| |. ||  .|. || | ...... .|||.||||||||| |  |.. ..|||||||..||.|||||||| |||||..| 
llevvelksksvseflsglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfserc

GQGDSKHlDERSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEIlVNGLYSNRFGTFLYNTVREREINKVQLETASIWSLILSNYSFYINQNYTRMDK--V
|. |...  | ||.| ||.|||....||| . |||| . |.|.  . .|| .||||| |. ..|. .|..  | |.|. .|.. . |.|  |.   .  |
Glldeds.kevsPiftqflecvwqlleqfpkafefnerfllel.hdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekev

LIPSIAIPYFSLWKDYYLKY
| |..|   ..||.  | ..
lkpdtapaalklwralynrf
Myotub-related Myotubularin-like phosphatase domain 972-1131 1e-64 211.5 Pfam-A 191-351 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 972-1131 1e-64 211.5 In-house 191-351 (353) alignment
subfamily_MTMR5_pd Subfamily MTMR5 638-1183 5.6e-60 195.5 In-house 13-480 (483) alignment 
Range on Protein: 638-1183
Range on HMM: 13-480/483.0
EYKRMNIK------AGSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPlvglTGSRCIDdellikQI
.|||. .       .   .|||..|.... |.||| |||||... | ..  |     ..|.||  |.|. |.... | ...    ...  ..       .
dykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf....eskgvvg......ll

SSPTIIQQPQSQQQSSSPPPSFINYSSTTsTNSTPNLNQINNInDNFKSLNNSGNSIVFNKRQSYISNSlsnlesslvsN------NNNNNSNI------
 | .  .. .|....||  .    |..    |....|....    . ..  .. .|   ..... .|..          .      .... |.       
ksantqgsstsessessksleqekylkav.vnevsklsalaln.sslevslsvlasssssdkraalste..........knaldisksdkasqggkgatl

NnnnnnnnvekilnlldarpkvnamsnkafmgagfenvstfysccnidflnignihvmrdsyeklkstcidslggikeiKNSNNTNQDNNNNNFNLNNSN
.                                                                              .|. .... .. ..  |    
k..............................................................................ennakeskklrarkaaLYvlg

snNNNNNTNVNSDNNNNNNIVRSESEEELSSfLLENETPISSIHSSdiidnNEGYNGTNIKWFEGIESSRWFDHIILILKGSIRIVESIHKQCTSVLIHC
  .  .  ||.|. ... ...  |. |.  .     .  .    .|     ..  . ..  . . .| | |.  |  .|. |  .|. .  |  |||.  
..eksqlknvksevdskaefipvelveirqv.kasfkkllraClps.....taveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvsl

SDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRIGQGDSKHLDERSPVFVQFIECVYHIMEQFKNYFEFNSQvLVEILVNGLYSNRF
 |||| | |.||.. ..||||||||||| ||.||||| |||.|..|  |  |.     .|||.||..||. ...||   ||||.   ...|     ||||
EdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndf.ylkflayhsvsnrf

GTFLYNTVREREI----------NKVQLETASIWSLILSN---YSFYINQNYTR-MDKVLIPSIAIPYFSLWKdYYLK
 |||...  ||            .. .  . |.|  |  .    . . |  |.   ..|| ||  .. ...|. |||.
rtfllDseyerlesgllyeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWd.yyle
subfamily_MTMR9_pd Subfamily MTMR9 966-1184 6e-54 175.6 In-house 171-392 (393) alignment 
Range on Protein: 966-1184
Range on HMM: 171-392/393.0
DIIDNNEGYNGTNIKWFEGIESSRWFDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDR
 ...  .  . .. |... .|.| |....  .|. .  ........ ..|..| ..| | | |..|.....|||..||..||  |||.||.. || |. |
klleacsdaglstdkflsrleksgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasR

IGQGDSKH--LDERSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEILVNgLYSNRFGTFLYNTVREREINKVQLETASIWSLILSN--YSFYINQNYTRM
  .   |.   ....|||. |..||| |..||   |||| ..|. .  .  || .|||||... .||. .|.. .| |.|| . ..   . ..|  | . 
askvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfeh.syssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyean

DKVLIPSIAIPYFSLWKDYYLKY
..|..||.| . ..||.. ||..
aeviwpsvapqslelWselylrw
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 960-1183 2.1e-53 173.6 In-house 184-403 (405) alignment 
Range on Protein: 960-1183
Range on HMM: 184-403/405.0
SSIHSSDiIDnNEGYNGTNIKWFEGIESSRWFDHIILILKGSIRIVESIHKqCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFG
....||   | ..  . |.....  || . |  ||  ||. .    | | |   |.|.|||||||||||..|.. |.|||||||. || |||||||| ||
lamkssa.rd.kdhtestdmrfwgyieetgwishiksileaatfsaelilk.gnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfg

HKFNDRIGQGDSKHlDERSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEIlVNGLYSNRFGTFLYNTVREREINKVQLETASIWSLILSNYSFYINQNYT
|||  |.|.   .  .||||.| ||..|......||   |||   .|. |  . ..| ..|||| |  ..|  ..|.. | |||| .  |   ..|  | 
hkfslrlghlpgne.eerspifqqfldccfqllsqfpllfeftpslllfi.sdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyyn

RMDK-VLIPSIAIPYFSLWKDYYLK
  |   . | .    . |||  |..
pqdiqsikpklysrclelwkacymr
Myotub-related Myotubularin-like phosphatase domain 625-893 6.1e-48 156.4 Pfam-A 16-190 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 625-893 6.1e-48 156.4 In-house 16-190 (353) alignment
subfamily_MTMR10_pd Subfamily MTMR10 964-1140 1.2e-36 118.3 In-house 138-312 (380) alignment 
Range on Protein: 964-1140
Range on HMM: 138-312/380.0
SSDIIDNNEGYNGTNIKWFEGIESSRWFDHIILILKGSIRIVESIHKQCTSVLIHCSDGWDRTPQLSSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFN
.  .||. | .  .. ||.  .|..|| . . |.|. .. .|. .... .||..  |.| |    ..| . .||||.|||..||  ||.|||   ||.| 
eLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfl

DRIGQGDSKHlDERSPVFVQFIECVYHIMEQFKNYFEFNSQVLVEiLVNGLYSNRFGTFLYNTVREREINKVQLETA
||.|.....  ...||||. | .||.  .||| . |||. ..|.  |.   .|  |.||| |. ..|. ..|. .  
drlghikpse.ksespvfllFldcvdqlleqfpseFeFtetfLia.lwdsshsgifltflfnseeqrlkavvssspl
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 625-731 1.1e-33 108.6 In-house 11-123 (405) alignment 
Range on Protein: 625-731
Range on HMM: 11-123/405.0
DKINGWLIYNSEREYKRMNIKAG---SG---WRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTG
. |.|| .|| ..|| |.||..    |.   |....||...| | ||.  .|| .  .| .|  .| |||||||| |||| ||  ..|.||||||||.  
ssidgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgier

SRCIDDELLIKQI
.|| .|||   ..
arcpedelycssl
subfamily_MTMR3_pd Subfamily MTMR3 634-749 6.4e-33 107.2 In-house 28-143 (442) alignment 
Range on Protein: 634-749
Range on HMM: 28-143/442.0
NSEREYKRMNIKAGSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTGSRCIDDELLIKQISS
. . |..|.  .  . ||||..|.||| |.|||| ..||..||| .| .|  ||| .|.|.. |.| .||. ..||||| ||. | |. .|| |.|.|. 
klkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiak

PTIIQQPQSQQQSSSP
 . ..... .....  
acaldagekakgekls
subfamily_MTMR1_pd Subfamily MTMR1 627-732 7.8e-33 106.3 In-house 4-109 (389) alignment 
Range on Protein: 627-732
Range on HMM: 4-109/389.0
INGWLIYNSEREYKRMNIKAGSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTGSRCIDDEL
 .|| .|. |.|..|. .     |||...|.... |..||...|||....| .|  |  ||||||.||||| ...|...|.|.|||||||.|.|. .|| 
edGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedek

LIKQIS
....| 
ylqail
subfamily_MTMR9_pd Subfamily MTMR9 628-787 7.7e-31 99.5 In-house 13-178 (393) alignment 
Range on Protein: 628-787
Range on HMM: 13-178/393.0
NGWLIYNSEREYKRMNiKAGSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTGSRCIDDELL
.|.  .. |.|....   | ..||||..|..||.|.|||. ..||..|.| .|. .  ||..||.||||. |  ..... |.||||.| .| || .|| |
dgysafdrenefakli.sasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedekl

IKQISSPT---IIQQPQSQQQSSS---PPPSF-INYSSTTSTNSTPNLNQINNINDNFKSLNNSGNS
.. . . .   .| ...|......     . .  . . . ..... .|.....|.| .  | .. . 
lnlvlkklkkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsd
subfamily_MTMR6_pd Subfamily MTMR6 625-733 2.6e-28 91.4 In-house 14-120 (397) alignment 
Range on Protein: 625-733
Range on HMM: 14-120/397.0
DKINGWLIYNSEREYKRMNIKAgSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTITRCSQPLVGLTGsRCIDD
 | .||  .... ||.|| .   . | .. .|.|.. |..||. ..||...| ..||    ||||||.||||. | .| ..| |||||| |..  || .|
ekvsGwklldlkaeytrmgvpn.ekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqplsgfsa.rcled

ELLIKQISS
| |.. |..
eklleairk
subfamily_pats1_pd Subfamily pats1 975-1071 2.1e-23 74.6 In-house 364-462 (691) alignment 
Range on Protein: 975-1071
Range on HMM: 364-462/691.0
NGTNIKWFEgIESSRWFDHIILILKGSIRIVESIHkQCTSVLIH-CSDGWDRTPQL---SSISMIMLDPYYRTLEGFIVLIEKEWLEFGHKFNDRIGQGD
.|.. .| | || | | | . |.|......   .  . .|||..  .|. . . .|   ||......||.||||.|| ||||||||..|. |...    .
dgsddewke.ieeskwvdsvkllleaavkvsnlld.eGssvllknsidsPlieldlasisslaqvlsdPfyrtldGfkvliekewlsyGfPfskinyhke

S
|
s
subfamily_pats1_pd Subfamily pats1 1078-1159 4.3e-19 60.4 In-house 553-633 (691) alignment 
Range on Protein: 1078-1159
Range on HMM: 553-633/691.0
SPVFVQFIECVYHIMEQFKNYFEFNSQVLVeILVNGLYSNRFGTFLYNTVREREINKVQLETASIWSLILSNYSFYINQNYT
||.||||.. |. .  .|  .|||| ..|. .||.  .| |||.|||.  ...  .||  .. ||||.|  | | .||  | 
sPifvqfldlvwqlqkefPfhfefneslll.llvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllyk
subfamily_MTMR1_pd Subfamily MTMR1 800-895 1.4e-15 49.5 In-house 86-179 (389) alignment 
Range on Protein: 800-895
Range on HMM: 86-179/389.0
SLSNLESSLVSNNNNNNSNINNNNNNNNVEKILNLLDARPKVNAMSNKAFmGAGFENVStFYSCCNIDFLNIGNIHVMRDSYEKLKSTCIDSLGGI
.   |     . .....  ...  . |.  . | .||||..|||..|||  | | |. . .|  ... ||.|.||||.|.|..|||  .. ..   
asqplvGlsgkrskedekylqaileanaqsekllildarssvnavankak.gkgyesee.aYknaelifldihnihvvReslkklkelvlpnvddk
subfamily_MTMR6_pd Subfamily MTMR6 811-888 6.6e-15 47.3 In-house 107-182 (397) alignment 
Range on Protein: 811-888
Range on HMM: 107-182/397.0
NNNNNNSNINNNNNNNNVEKILNLLDARPKVNAMSNKAfMGAGFENVsTFYSCCNIDFLNIGNIHVMRDSYEKLKSTC
  ..... ..  .. |.  ..| ..|.|||.||..|||  | |.||   .|| ....|..| ||||||.| .||  ..
rcledeklleairkanpnsellyvvdtrpklnalanka.agkGyene.dnysnikfqfvgienihvmreslqkllevv
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 795-888 2e-13 41.9 In-house 99-186 (405) alignment 
Range on Protein: 795-888
Range on HMM: 99-186/405.0
SYISNSLSNLESSLVSNNNNNNSNINNnnnnNNVEKILNLLDARPKVNAMSNKAfMGAGFENVSTfYSCCNIDFLNIGNIHVMRDSYEKLKSTC
|  |. |  .| . . ...   |..          | | |.|||||.||..| |  ||||||.   |  |.. |.|| ||||.| | ||| .. 
srcsqplvgierarcpedelycsslal....sapsktlylidarpklnaianta.ngagfenihn.ypncklvfmnipnihvirksleklvlam
subfamily_MTMR3_pd Subfamily MTMR3 793-891 3.6e-13 42.1 In-house 138-232 (442) alignment 
Range on Protein: 793-891
Range on HMM: 138-232/442.0
RQSYISNSLSnlESSLVSNNNNNNSNINNNNNNNNVEKILNLLDARPKVNAMSNKAfMGAGFENvSTFYSCCNIDFLNIGNIHVMRDSYEKLKSTCIDS
... .||. .  ... ||.. ...........  . .| | ..|||    |..|.|  | |.|. . .|..|.. ||...||| .| |...|.. . .|
kgeklsngka..kkkdvsdaldaeadaseeeslaeekkkllivdarsytaafanra.kgGGcel.eeyypncevvflglanihavrksfnslrallsqs
subfamily_pats1_pd Subfamily pats1 628-708 9.9e-13 39.3 In-house 4-82 (691) alignment 
Range on Protein: 628-708
Range on HMM: 4-82/691.0
NGWLIYNSEREYKRMNIKAGSGWRISTINnDFKKCESYPKLIVVPETITDTqLVDVFIFRSKGRIPVLSWKHPSNGTTITR
. . ||    |..|....    ||. ..  . . .| ||| |.||....|  |.  .. . . .|||||| ...| ... |
eifdiyslliegqrlkldldkdwrvvefl.srdlseiyPkrilvPklvsde.llvsyvrkrsskiPvlswsnqnnksslfr
PTPc_DSPc_SM00012 999-1107 1.4e-09 33.5 In-house 20-98 (105) alignment 
Range on Protein: 999-1107
Range on HMM: 20-98/105.0
KGSIRIVESIHKQCT------SVLIHCSDGWDRTPQLSSISMIMLDPYYRTlegfivliekewlefghkfndrigqgdskhlderspVFVQFIECVYHIM
.  ........|. .      .|..|||.|..|| ..  ..... . ...|                                     .|.. ..| ...
dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket....................................kevdifqivkelr

EQFKNYFEFNSQVLV
.|  ...... |.|.
kqRpgmvqteeqylf
subfamily_MTMR10_pd Subfamily MTMR10 644-706 1.7e-08 25.7 In-house 20-82 (380) alignment 
Range on Protein: 644-706
Range on HMM: 20-82/380.0
IKAGSGWRISTINNDFKKCESYPKLIVVPETITDTQLVDVFIFRSKGRIPVLSWKHPSNGTTI
 ..  ... .. |. |. ....|. .|||....| .. ...    ..| |...|.|..  . .
ktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaall
0049772 (Phosphotyrosine protein) phosphatases II 933-1038 1.2e-07 27.3 In-house 118-238 (314) alignment 
Range on Protein: 933-1038
Range on HMM: 118-238/314.0
NNNNN---------------------------------NIVRSESEEELSsfllenetpissihssDIIDNNEGYNGTNIKWFEGiessRWFDHIILILK
 .|                                   |.   .  |.|                 ......| . ...||..       . |.   .|.
dlnvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellk................eelydpelferlgikylri....pvpDgsaplle

GSIRIVESIHK--QCTSVLIHCSDGWDRTPQLSSISMIMLD
   ...| |..  . . ||.||..|..||. .  . ..|. 
dfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkl
subfamily_MTMR14_pd Subfamily MTMR14 1006-1070 1.8e-07 22.3 In-house 261-332 (357) alignment 
Range on Protein: 1006-1070
Range on HMM: 261-332/357.0
ESIHKQC-TSVLIHCSDGWDRTPQLSSISMIML---DPYYRTLEG---FIVLIEKEWLEFGHKFNDRIGQGD
......  . .|.||  ||||||   |.  . |      ...|.      . .  .|. |||.. ||. .|.
kyvkededsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrlkkge