Gene DDB_G0285967 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTEN
Subfamily PTEN
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP041_AA protein Get Run
DdisP041_AA_3-195 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTEN_pd Subfamily PTEN 4-183 1.1e-84 278.0 In-house 2-181 (184) alignment 
Range on Protein: 4-183
Range on HMM: 2-181/184.0
VRKMVSKKKRRFEMYNFDLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEYPFDDHCPPTLNIISEF
.||.|||||.||.  ..||||||||...||||.|.|.||.||||...||..|... |.||||.|||.|||||.. .|..||..||||||.||.|....|.
lrkivskkkkrfkedgldLDlsyiteniiamgyPaeklealyRnsledvvkflekkhkdhykiynlrserkydskkfdgrvavypfdDhnppplelleei

CNDMEMWLDQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTGSESMRLFANKRTHNSKGVTIPSQIRYVRYFEALLQY
..|.|.||.....|||.|||||||||||......||....... .|...|||..||.|.||||||||.|||.|.|.||. 
vediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaRtknkkgvtiPsqrRYveYyekllee
subfamily_VSP_pd Subfamily VSP 3-189 1.8e-66 218.1 In-house 15-207 (212) alignment 
Range on Protein: 3-189
Range on HMM: 15-207/212.0
LVRKMVSKKKRRFEMYNFDLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEYPFDDHCPPTLNIISE
..|..||. |||..   |||||.|.|.|.||| |||   . |||| ...| ||..| | |||||.||||||.|..  |..||..   |||  |.|. .  
aarrlvsenkrrytqdGfdldltyvteriiamsfpssGkqslyrnpisevarfldtkhrdhykvvnlcseraydekyfnnrvkriliddhnvpkleellv

FCNDMEMWLDQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTGSESMRLFANKRTHNS-----KGVTIPSQIRYVRYFEALL-QYGKPIPK
|..... ||.....||.|.||| |||||||.. ..||. ....|  ||.  |...||...     .||  ||| ||| |.| .  .|.. .|.
ftkevkewlekdlknvlaihckGGkgrtGtivcalllaseifetakesldyfgerrtdktegekfqGvqtpsqkryvgyleqvktkynrklpp
PTEN_1 11-183 1.6e-49 163.4 In-house 9-194 (196) alignment 
Range on Protein: 11-183
Range on HMM: 9-194/196.0
KKRRFEMYNFDLDLSYITDRVIAMG-FPSES-----LEGLYRNRMRDVQRFFNTLHADH-YKVYNLCSERKY------EHCRFEDRVS--EYPFDDHCPP
.|..    ...|||.|||.|.|||| .||..      |||||....||......|..|. . |.||..|...      .  .|. .|.  ..|..|| .|
skknlalptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgap

TLNIISEFCNDMEMWLDQNP-ENVVAVHCKAGKGRTGTMLACWLLYNKQcQTGSESMRLFANKRTHNSKGvtIPSQIRYVRYFEALLQY
.|. . ..|.... || ..| .|||.||||||.||.||..|..|.| ..  |  | ..|.. ||.....   .||| |...||. ||. 
slselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk.ltadeAlelvrekRppgapn..spsqerlleyfaellae
subfamily_Tensin_pd Subfamily Tensin 14-182 4.5e-48 156.2 In-house 3-172 (189) alignment 
Range on Protein: 14-182
Range on HMM: 3-172/189.0
RFEMYNFDLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLcSERKYEHCRFEDRVSEYPFDDHCPPTLNIISEFCNDMEMWLDQ
|.  ...||||.|||.|.||. ||.|.||  ||. ..|| ..... | |.| |.|| ||..|.  .....| .. . |.  |.|. ..  |.... ||..
ryveekvdldltyiteriialsfpaegleekyrenlkdvakllkskhndkylvfnl.sekrydisklnkkvldfGWPdllaPsleklcsicksldsWlka

NPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTGSESMRLFANKRTHNSK--GVTIPSQIRYVRYFEALLQ
.|.|||.|||| ||||.| ...... |.| ... ....  || ||  ..|  |.| ||| |||.||..||.
dpqnvvvvhckGgkgrigvvvsaymkyskisasadaaldrfamkrflddklsgetqPsqrryveyfsglLs
0036282 (Phosphotyrosine protein) phosphatases II 21-181 1.7e-43 143.7 In-house 9-169 (174) alignment 
Range on Protein: 21-181
Range on HMM: 9-169/174.0
DLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEYPFDDHCPPTLNIISEFCNDMEMWLDQNPENVVA
.|||||||.|.||...| . .| |.... ..| .. .  . ..||..|...|...   |.  ..  .|..||..|.|.|. ||.. .| .| ..|...|.
pldlsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvl

VHCKAGKGRTGTMLACWLLYNKQCQTGSESMRLFANKRTHNSKGVTIPSQIRYVRYFEALL
|||.||.|||||. |..|..  ....  . ..|.. .|......|..|||.|...||| ||
VHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll
subfamily_Auxilin_pd Subfamily Auxilin 21-182 1.5e-42 138.2 In-house 8-165 (166) alignment 
Range on Protein: 21-182
Range on HMM: 8-165/166.0
DLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLcSERKYEHCRFEDRVSEYPFDDHCPPTLNIISEFCNDMEMWLDQNPENVVA
|||.|||| |.| | ||.| .|  |.| . ||. | .. | ..|.|||| |.|.|.. ... ||.|. .  .  | |. . | | .. .|| ..|.||| 
dlDisyitsriivmsfPaegvestyknniddvrsfLesrhpekylvynl.sqrtyrtaklssrvveagwparraPnLeslvevcrnlyswlkkdpknvvv

VHCKAGKGRTGTMLACWLLYNKQCQTGSESMRLFANKRTHNSkgvTIPSQIRYVRYFEALLQ
|||| |.  ...... .|.. .  .. ....|||. ||.  .     ||. ||. |. .||.
vhckDGraasavlvsallvfcrllsepesavrlfsvkrlpig...lspsekryleyladlla
0038934 (Phosphotyrosine protein) phosphatases II 26-190 1.1e-41 137.9 In-house 15-179 (194) alignment 
Range on Protein: 26-190
Range on HMM: 15-179/194.0
YITDRVIAMGFPSES-----LEGLYRNRMRDVQRFFNTLHADHYKVYNLC-SERKYEHCRFED---RVSEYPFDDH-CPPTLNIISEFCNDMEMWLDQNP
.||.|.||...|...     .|.|||. ..|. |....|. ....|..|. .|| |....||.   .. ..|| |. ..|.|.|. .|.. .. .|...|
iitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedp

ENVVAVHCKAGKGRTGTMLACWLLYNKQCqTGSESMRLFANKRthnskgvtiPSQIRYVRYFEALLQYGKPIPKP
..|||||||||.|||||..|..|.|  .. .  |...||. ||         |..|... |.||||.. |.. | 
ggvvaVHCkaGlgRtGtlvaaYLiyrlgm.saeeAialfrekR.........pgaipnqdyleallkrykelrka
0046846 (Phosphotyrosine protein) phosphatases II 14-181 2.1e-34 114.2 In-house 2-172 (176) alignment 
Range on Protein: 14-181
Range on HMM: 2-172/176.0
RFEMYNFDLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTlhaDHYKVYNLCSERKYEHCRFED----------RVSEYPFDDHCPPTLNIISEF
|. .. .||||.||....|....|    ..|.|. . .......    ... | ||..|. ...... .          ..  .|..||..|.|... |.
rlrllgldldldyinanlilgsrpiatqgplprtladflemlkel...gitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllel

CNDMEMWLDQNpeNVVAVHCKAGKGRTGTMLACWLLYNKQCQTGSESMRLFANKRTHnsKGVTIPSQIRYVRYFEALL
.. .. .|...  ..|.|||.||.|||||..|..||. ... .  | ..|. ..| .  . |. |.|.|....|| ||
lefirealkeg..gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRpl..gavqtpeQyrflyefelll
0043147 (Phosphotyrosine protein) phosphatases II 20-181 1.5e-33 111.3 In-house 11-160 (172) alignment 
Range on Protein: 20-181
Range on HMM: 11-160/172.0
FDLDLSYITDRVIAMGFPsesleglYRNRMRDVQRFFNTLHADHykVYNLCsER---KYEHCRFEDRVSEYPFDDHCPPTLNIISEFCNDMEMWLDQNPE
..|||.||.||.||. .|       .|| . |. |.. .|. .|  ..||. |.   ..  .|.  ..  .|..||..|.|... ||.. .. .| ..|.
syldlyyipdrfiatqgp.......lrntladfwrmlkelgith..ivnlt.ellydpellerlgiqylylpwpDhgvpllellleflefidellalspg

NVVAVHCKAGKGRTGTMLACWLLYnkQCQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEALL
..|.|||.||.|||||. |..|..  .. .  | ..|. .||   ...|..|||.|...||| ||
gpvlVHCsaGvgRtgtlvaaylml..lglsleeavalvrekR...pgavqnpsqyrflyyfekll
0049260 (Phosphotyrosine protein) phosphatases II 32-181 5.2e-33 109.3 In-house 5-149 (152) alignment 
Range on Protein: 32-181
Range on HMM: 5-149/152.0
IAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEYPFDDHCPPTLNIISEFCNDMEMWLDQNPENVVAVHCKAGKGRTG
.||.|.    .|...| . |. |.. .|..... ... ..|.... | .  ..  .|..||..|.| .. .|....  .| ......|.|||.||.||||
yampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtg

TMLACWLLYnkqcqTGSESMRLFANKRTHNSKGVTIPSQIRYVRYFEALL
|. |..|..      | .    .|  |......|. |.|.|.. .|| ||
tlvaaylml.....lgvsleeavalvrekRpgavpnpgqlrflyefekll
0041856 (Phosphotyrosine protein) phosphatases II 15-185 8.6e-33 108.8 In-house 10-174 (182) alignment 
Range on Protein: 15-185
Range on HMM: 10-174/182.0
FEMYNFDLDLSYITDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYK-VYNLCsERKYEHCRFED---RVSEYPFDDHCPPTLNIISEFCNDMEMw
. .|....||.||.........|.   .  ... ...| .|...|.  ... . ||. |. |   ..|.   ..  .|..||..|.|... .|.....  
ilpydhsrdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywpellerlgiqylylpwpDhgvpdldelldfieevle.

ldqnPENVVAVHCKAGKGRTGTMLACWLLYNKQcQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEALLQYGK
    ....|.|||.||.|||||. |..|.. ..  .  | ..|. ..|   ...|..|.|........ .|...|
....eggpvlVHCsaGvgRtgtlvaaylmkklg.vsleeavklvrsrR...pgmvitpnqyfflqlallellllk
0039614 (Phosphotyrosine protein) phosphatases II 5-180 1.6e-32 108.6 In-house 52-287 (297) alignment 
Range on Protein: 5-180
Range on HMM: 52-287/297.0
RKMVSKKKRRFE--------------MYNFDLDLSYI-----------TDRVIAMGFPSESLEG-----LYRNRMRDVQ---------------------
.. ..|.|.|.               . ..|||..||           |...||...|...  .     ..... . .                      
llpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg

-------RFFNTLHADHYKVYNLCSERkYEHCRFEDRVSEYPFDDHCPP-TLNIISEFCNDMEMWLDQN-PENVVAVHCKAGKGRTGTMLACWLLY----
       .. .. | |.|.|..|. .. ..  |.  ..  ... ||..| .|... ||.. .. .| .. ....|.|||.||.|||||..|..|..    
tygdftvtllkvehldgytvrtlevtn.ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqle

NKQCQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEAL
 ... .  | .. . ..|   ...|..|||.|....... 
keggvdvleavkelreqR...pgavqtpsqyrflydalle
0037934 (Phosphotyrosine protein) phosphatases II 6-180 1e-30 102.5 In-house 7-240 (243) alignment 
Range on Protein: 6-180
Range on HMM: 7-240/243.0
KMVSKKKRRFE--------------MYNFDLDLSYITDRVIAMGFPSES---------LEGLYRNRMRDVQ----------------------------R
......|.|.                  ....|.|.|.|.||...| ..         .. |.... . .                             .
lpenlsknrysdilpydhsrvklegsdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvt

FFNTLHADHYKVYNLCSER--KYEHCRFEDRVSEYPFDDHCPPT-LNIISEFCNDMEMWLDQ-------NPENVVAVHCKAGKGRTGTMLACWLLYNKQC
. .. | |.|.|..|. |.   ....|.  ..  .|. ||..|.  ... .|....  ....       .....|.|||.||.|||||..|..|.. . .
llseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllg

QTGSESMRLFANKRTHnsKGVTIPSQIRYVRYFEAL
 .  | ..|. ..| .  |.|..|||.|....... 
vdleeavkllreqRpg..kavqtpsqyrflyealle
0043336 (Phosphotyrosine protein) phosphatases II 7-179 5.4e-30 100.2 In-house 43-274 (278) alignment 
Range on Protein: 7-179
Range on HMM: 43-274/278.0
MVSKKKRRF-------------EMYNFDLDLSYI----------TDRVIAMGFPSESLEGLYRNRMRDVQ------------------------------
. .|.|.|.             .....|||..||          ....||...|... .. ... ... .                              
penkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltyg

----RFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEY-PFDDHCPP-TLNIISEFCNDMEMWLDqNPENVVAVHCKAGKGRTGTMLACWLLY----NKQ
    .. .. | |.|.|..|. ......  .. ..  | .. ||. | .|... .|....  .|. .....|.|||.||.|||||..|..||.    . .
dftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeg

CQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEA
. .  | .. . ..|    . |. |||.|.......
gvdleeavkelreqR...pgavqtpsqyrflyeall
0042113 (Phosphotyrosine protein) phosphatases II 4-180 2.4e-29 97.9 In-house 4-241 (245) alignment 
Range on Protein: 4-180
Range on HMM: 4-241/245.0
VRKMVSKKKRRF-------------EMYNFDLDLSYI----------TDRVIAMGFPSESLEG-----LYRNRMRDVQ----------------------
 .....|.|.|.               ...|||..||          |...||...|...  .     |.... . .                       
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges

--------RFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEY-PFDDHCPPT-LNIISEFCNDMEMWLDQNPENVVAVHCKAGKGRTGTMLACWLLY---
        .. .. | |.|.|..|. ....... .|...  | |..||..|. |... .|.. .. .| ......|.|||.||.|||||..|..|..   
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql

-NKQCQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEAL
   .. .  | .. . ..|   .. |..|||.|....... 
ekelgvsleeavkelrsqR...pgavqtpsqyrflyealle
0040438 (Phosphotyrosine protein) phosphatases II 6-182 1.7e-28 95.2 In-house 40-276 (317) alignment 
Range on Protein: 6-182
Range on HMM: 40-276/317.0
KMVSKKKRRF-------------EMYNFDLDLSYI----------TDRVIAMGFPSES-----LEGLYRNRMRDVQRFFNTL------------------
. ..|.|.|.               ...|||..||          ... ||...| ..     .. ..... . . .. ..                   
lpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetlt

------------HADHYKVYNLCSERKYEHCRFEDRVSEYPF-DDHCPP-TLNIISEFCNDMEMWLDqNPENVVAVHCKAGKGRTGTMLACWLL-----Y
            . .......|. | ...   .. ..  |.. .||..| ..... .|.. .. .|. .|...|.|||.||.|||||..|..|.     .
ygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlek

NKqCQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEALLQ
.. . .  | .. . ..|   ...|. |.|.|.. .... . 
eg.gvdveeavkelreqR...pgavqtpeqyrflydalleyl
0040439 (Phosphotyrosine protein) phosphatases II 6-181 1.2e-27 92.6 In-house 8-245 (249) alignment 
Range on Protein: 6-181
Range on HMM: 8-245/249.0
KMVSKKKRRFE-MYNFD----------------------LDLSYITDRVIAMGFPSESLEGLYRNRMRDVQ-----------------------------
....|.|.|.   . .|                      .|..||..|.||...| ..  . ... ... .                             
lpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsle

------RFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEY---PfDDHCPPTLNIISEFCNDMEMWLDQN-PENVVAVHCKAGKGRTGTMLACWLLY---
      ..... . |.|.|..|. ...|.   .. ..  |   | |...||..... .|.. .. .|... ....|.|||.||.|||||..|..|..   
ygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleql

-NKQCQTGSESMRLFANKRthnSKGVTIPSQIRYVRYFEALL
  ... .  | ..|. ..|   ...|. |.|.|.. .... |
ekelgvdleeavkllrsqR...pgavqnpeqyrflyeallel
0045450 (Phosphotyrosine protein) phosphatases II 10-182 4.3e-27 91.1 In-house 56-304 (307) alignment 
Range on Protein: 10-182
Range on HMM: 56-304/307.0
KKKRRFEM-------------------------------------YNFDLDLSYI----------------------------------TDRVIAMGFPS
|.|.|.                                         .||.. .|                                  ... .|. .|.
kdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPd

ESLEGLYRNrmrDVQRFFNTLHADHYKVYNLCSERKyEHCRFEDRVSEYPF----DDHCPPTLNIISEFCNDMEMWLDQN-PENVVAVHCKAGKGRTGTM
|. |  |.|   .. .. .. | |.|.|..|. ... . . .. .|  ...    |...||..... .|.. .. .|... ....|.|||.||.|||||.
egeeltygn...ftvtllseehldgytvrtlevtdl.dgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtf

LACWLLYNKQCQTGS-------ESMRLFANKRthnSKGVTIPSQIRYVRYFEALLQ
.|..|..    ..|        | ..|. ..|   ...|. |.|.|....... | 
iaaylmlrqlekegtlldvdlleavkllreqR...pgavqnpeqyrflyeallell
0051082 (Phosphotyrosine protein) phosphatases II 22-178 6.8e-27 89.3 In-house 6-148 (151) alignment 
Range on Protein: 22-178
Range on HMM: 6-148/151.0
LDLSYITDRVIAMGFPSEsleglyrnrmrDVQRFFntLHADHYKVYNLCS--ERKYEHCRFED---RVSEYPFDDHCPPTLNIISEFCNDMEMWLDQNPE
...||.|......|.|..           |. ...   . ... ..||.|  ||.|.......   .|  .|..|...|.| .. ......  .|.....
infsyvtgglyrsggpla...........dflell..kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkn

NVVAVHCKAGKGRTGTMLACWLLYnkQCQTGSESMRLFANKRThnskGVTIPSQIRYVRYFE
..|.|||.||||||||. |..|..  .  .  | .. .  ||.    ||..|.| ... .|.
gpvlvHCsaGkgRTGtlvalylml..lgvsleealeeyrlkrp....gvvqpnqqflfqlfa
0049772 (Phosphotyrosine protein) phosphatases II 16-195 1e-26 89.9 In-house 96-291 (314) alignment 
Range on Protein: 16-195
Range on HMM: 96-291/314.0
EMYNF-----------------DLDLSYITD---------------------RVIAMGFPsesleglyrnrmrdvqrffNTLHADHYKVYNlcsERKYEH
 ...|                 ||.. .|                         |..|..                   | ..| ... ..   |. |..
tvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng...................neptaadlellk...eelydp

CRFEDRVSEY---PFDDHCPPTLNIISEFCNDMEMWldqNPENVVAVHCKAGKGRTGT-MLACWLLYNKQCqTGSESMRLFANKRTHNSKGVTIPSQIRY
 .||... .|   |..|...|.|... ||.. .| .   .....|.|||||||||||| ..|..|..  .. .  | .. . .||. | . ..|.....|
elferlgikylripvpDgsaplledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRpinpnpgfieqleqy

VRYFEALLQYGKPIPKPPSITK
. ..||||.| | ..| .....
efilealleylkflkkfyeyle
0048179 (Phosphotyrosine protein) phosphatases II 36-180 4.3e-26 86.8 In-house 3-143 (144) alignment 
Range on Protein: 36-180
Range on HMM: 3-143/144.0
FPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFED-RVSEYPFDDHCPPTL-NIISEFCNDMEMWLDQNpeNVVAVHCKAGKGRTGTM
.||| |.|||.. . ..... .  . ... |.||..|. .|.. .|  ..  .|..||..|.| ... ||.. .| .|...  ..|.|||.||.|||||.
npseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg..gpvlVHCsaGvgRtgtl

LACWLLYNKQcQTGSESMRLFANKRThnsKGVTIPSQIRYVRYFEAL
 |..|.. ..  .  | ..|. ..|     .|. |.|.|.....| |
vaaylmkklg.lsleealalvrsrrp...gavpnpgqlrfLleyekl
0048076 (Phosphotyrosine protein) phosphatases II 36-181 5.5e-26 86.4 In-house 3-142 (145) alignment 
Range on Protein: 36-181
Range on HMM: 3-142/145.0
FPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHcRFEDRVSEYPFDDHCPPTL-NIISEFCNDMEMWLDQNpeNVVAVHCKAGKGRTGTML
.||| |.|||.. . ..... .  . ... |.||.||....  |.  ..  .|..||..|.| ... ||.. .| .|...  ..|.|||.||.|||||. 
wpseilpglylgslptaldlellkdlgittvlnltselelle.rlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlv

ACWLLYNKQcQTGSESMRLFANKRTHnskGVTIPSQIRYVRYFEALL
|..|.. ..  .  | ..|. ..| .   .|. |.|.|....||  |
aaylmlllg.vsleealelvrsqrpg...avpnpgqlrflyefelel
0045098 (Phosphotyrosine protein) phosphatases II 17-181 1.9e-25 85.2 In-house 2-271 (278) alignment 
Range on Protein: 17-181
Range on HMM: 2-271/278.0
MYNFDLDLSYITDRVIAMGFPSESLEGLYRNRMR------------------------------------------------------------------
. ...|||..........|.||| ...||.. .                                                                   
ealasldlllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvel

-------------------------DVQRFfNTLHADHYKVYNLCSERKYEHCRFEDRVSEYPFDDHCPPTLN---IISEFCNDMEMWLD----------
                         ..... .. .  ...|.||..||..  .|.   .  .|..||..|.|.    . |... .. .|.          
grekcaqywpeggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl

--QNPENVVAVHCKAGKGRTGTMLACWLLYNKQcQTGSESMRLFANKRTHNSK-GVTIPSQIRYVRYFEALL
  ......|.|||.||.|||||. |..|..    . |      ..  |..     |....|.|.. .|...|
llldsggpvlVHCsaGvgRtGtlvaaylmlell.eggvdlleavkelrsqRpglavqnleqyrflyefllel
PTEN_C2 C2 domain of PTEN tumour-suppressor protein 193-312 8.1e-24 75.3 Pfam-A 4-132 (134) alignment 
Range on Protein: 193-312
Range on HMM: 4-132/134.0
ITKVLSMIKMNSLPNFNIGGGCEPYLSIVQQGKSVFySKPVKLKKGTIH--QQVELDCG-NILLVNDVQIQFFNRN----SKGHMFSYCFHTAFIE--GT
 .  |. | ....|||...|||.|.. .... |.|| ... . |. | .  ... ..   .... .|| ..|....    .|  .|   |.|.|||   .
krlelksiilegiPnfktrggckpkvkvyngkkkvf.kelasykdsterraktfivkepnrlpveGDvlveflhkdsklpkkekifrvwFNTsFieknqn

KIHIRRQEIDKAHKD-LKHFHSNFSIELIF
 . ....|.|||.||  |.|..||..||.|
vltlpkneLDkalkdkdkkfsknfkvelvf
0044763 (Phosphotyrosine protein) phosphatases II 9-184 9.5e-24 79.4 In-house 8-173 (178) alignment 
Range on Protein: 9-184
Range on HMM: 8-173/178.0
SKKKRRFEMYNFDLDLSYITDRVIAMGFPSesleglyrnrmRDVQRFFNTLHADHykVYNLCSE--------RKYEHCRFEDRVSEYPFDDHCPPT-LNI
.  ... . . . ...|.|.........|.            |  ...  |. .|  . ||..|         .|   ... ..  .|..||..|. | .
llsnleglersdyinaseilpglylgslpp...........addlellkelgith..ivnlteelelgflkcdpywpeeagiqylhipipDhgvpdlleh

ISEFCNDMEMWLDQNPeNVVAVHCKAGKGRTGTMLACWLLYNKQCqTGSESMRLFANKRthnSkGVTIPSQIRYVRYFEALLQYG
. ||.. .| .||... ..|.|||.||.||.||. |..|..  .. .  | ..|. ..|   . .|. |.|.|....||  |.  
flefvefieealdekg.gpvlVHCsaGvgRsgtlvaaylmkklgl.sleeaielvrerR...p.ivpnpgqlrqLyefelrllke
0046845 (Phosphotyrosine protein) phosphatases II 19-178 3.6e-23 77.8 In-house 67-270 (284) alignment 
Range on Protein: 19-178
Range on HMM: 67-270/284.0
NFDLDLSYITDRVIAMGFPSES-----------------------------LEGLYRNRMRDVQRF-------FNTLHADHYKVYNLCSERKY-EHCRFE
 .||||.||. . ||. .| ..                                 |.. . .|...        .. . |.|.|..|. ...  .   ..
gydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrt

DRVSEY---PfDDHCPPTLNIISEFCNDMEMWLDQ-NPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTG-------SESMRLFANKRthnSKGVTIPSQ
 ..  |   | |...||..... ||..... .|.. .......|||.||.|||||..|..||..   ..|        | .. . ..|      |. ..|
vthfhytswp.dhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqR...pgmvqtleq

IRYVRYFE
.|.| .. 
yrfvyeal
0047943 (Phosphotyrosine protein) phosphatases II 55-176 4.6e-20 67.7 In-house 141-266 (273) alignment 
Range on Protein: 55-176
Range on HMM: 141-266/273.0
FFNTLHADHYKVYNLCSERKYEHCRFEDRVSEYP-FDDHCPP-TLNIISEFCNDMEMWLDQN-PENVVAVHCKAGKGRTGTMLACWLLY----NKQCQTG
. .. . |.|.|..|. ...  .  .. ..  |. . ||. | .|... ||..... .| ..  ...|.|||.||.|||||..|..||.     ... . 
llseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdv

SESMRLFANKRTHnskGVTIPSQIRYVRY
 | ..|. ..| .   .|. |.|.|.. .
leavkllrsqRpg...mvqtpeqyrflye
0051299 (Phosphotyrosine protein) phosphatases II 55-175 6.9e-20 67.1 In-house 153-279 (288) alignment 
Range on Protein: 55-175
Range on HMM: 153-279/288.0
FFNTLHADHYKVYNLCSERK--YEHCRFEDRVSEYPF----DDHCPPTLNIISEFCNDMEMWLDqNPENVVAVHCKAGKGRTGTMLACWLLYNKQ-CQTG
. .. . |.|.|..|. ...  .. . .. .|  . .    |...|.... . .|....  .|  .....|.|||.||.|||||..|..||..   .. |
llseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekegg

SESMRLFANKRTHNSKGVTIPSQIRYVR
 . .....  |..    |. |.|.|.| 
vdvleavkrlreqRpgmvqtpeqyrfvy
0036941 (Phosphotyrosine protein) phosphatases II 36-184 5.2e-16 54.3 In-house 124-279 (297) alignment 
Range on Protein: 36-184
Range on HMM: 124-279/297.0
FPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEY-PFDDHCPPT-LNIISEFCNDMEMWLDQN-PENVVAVHCKAGKGRTGT
.|.|  | |. ....   . ... . |.|....|. . . .   .. ..  |   .||..|.  ... .|.. .. .|..  ....| |||.||.||.||
wpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgt

MLACWLLYNKQC---QT-GSESMRLFANKRTHNSKGVTIPSQIRYVRYFEALLQYG
..|..|...  .    . |     ..   |..    |. ..| |....... | . 
fiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkk
0050432 (Phosphotyrosine protein) phosphatases II 52-173 4.8e-15 51.1 In-house 150-290 (308) alignment 
Range on Protein: 52-173
Range on HMM: 150-290/308.0
VQRFF------NTLHADHYKVYNLCSERKYEHCRFEDRVSE-------------Y---PfDDHCPPTLNIISEFCNDMEMWLdqnPENVVAVHCKAGKGR
  ...      ..|. ....|..|. | . ...... ...              |   | |...|| ..|. .|.. .. .|   |.....|||.|| ||
caqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWp.dhgvPpspeilldflelvrksl...pggpivVHCsaGvGR

TGTMLACWLLYNKQCQ-TGSESMRLFANKRTHNSKGVTIPSQIRY
|||..|..||..   .  |     ...  |..    |. |.| ..
tGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylf
LIM LIM domain 709-762 7.7e-14 39.6 Pfam-A 1-56 (58) alignment 
Range on Protein: 709-762
Range on HMM: 1-56/58.0
CYGCKLPIVDE-VMMDALNFKWHVACLVCSKCAIQIEGQ-LGDHQGLIYCKDHFEE
|.||. .| |. ... ||. ..|..|..||.|  ... . .  . | .|||... .
CagCnkkiadrelvlkalgkvyHeeCFtCseCqkplkeksffekdgklyCkkdylk
subfamily_PTPDC1_pd Subfamily PTPDC1 85-182 3.5e-13 44.4 In-house 86-176 (182) alignment 
Range on Protein: 85-182
Range on HMM: 86-176/182.0
SEYPFDDHCPPTLNIISEFCNDMEMWLDQNpenVVAVHCKAGKGRTGTMLACWLLYNKQCqTGSESMRLFANKRThnsKGVTIPSQIRYVRYFEALLQ
 .....|.  ..|. | .    ... |...    ||||| ||.|||| ..||.|.|.|.  |......|  .||.   | .   .|.. |. |...|.
ynfgwkDygvasleriLdivkvvafalqeg...kvavhChaGlGrtGvliacylvyakrl.taekaiklvrskrp...ksiqtreqvelvkefalfli
subfamily_DSP23_pd Subfamily DSP23 89-147 7.3e-13 43.4 In-house 59-115 (148) alignment 
Range on Protein: 89-147
Range on HMM: 59-115/148.0
FDDHCPPTLNIISEFCNDMEMWLDQNpeNVVAVHCKAGKGRTGTMLACWLLYNKQCQTG
 ||..||.|. . || . .|   ..|  . |.|||  |.|||||||||.|. ...  ..
iddyhppaleqvvefvrvveeaeekn..eavsvhcllgrgrtgtmlacylvkerklaaa
subfamily_CDC14_pd Subfamily CDC14 28-143 2.1e-11 38.3 In-house 177-290 (328) alignment 
Range on Protein: 28-143
Range on HMM: 177-290/328.0
TDRVIAMGFPSESLEGLYRNRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRV---SEYPFDDHCPPTLNIISEFCNDMEMWldqnpENVVAVHCK
 |...|.  | .  .   . ...  .....  .  . .      .. |.. .|.|     ..  | |   |. .|. .| . .|       |  .|||||
PdkflalagPhnkskledgyplhaPeklleyfrknnvttvvrLnkklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaeka.....eGaiavhCk

AGKGRTGTMLACWLLYNKQ
|| |||||..||.|... .
aGLGrtGtLiacylmkhyr
LIM LIM domain 442-495 3.2e-11 31.3 Pfam-A 1-53 (58) alignment 
Range on Protein: 442-495
Range on HMM: 1-53/58.0
CPKCNLPITATDPSINRNSENYHWKCVVCVKCSKPLGGESdCVFENNEMLCTDC
| .|| .|....  .. . ..|| .| .| .|.|||. .| ..  .....| ..
CagCnkkiadrelvlkalgkvyHeeCFtCseCqkplkeks.ffekdgklyCkkd
0048567 (Phosphotyrosine protein) phosphatases II 74-158 5.5e-11 37.1 In-house 27-118 (157) alignment 
Range on Protein: 74-158
Range on HMM: 27-118/157.0
KYEHCRF-EDR--VSEYPFDDHCPPTLNIISEFCNDMEMWLD--QNPENVVAVHCKAGK---GRTGTMLACWLLYNkQCQTGSESMRLFANKR
 |. . |  |.  | | .| |. |..|.|. .|.. .. .|.  .. ....|||||||    |||.|...|.|..  .  | .| .....  |
lynalyFsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilh.lgftpeeaiaplrivr
subfamily_PRL_pd Subfamily PRL 51-140 6.1e-11 36.6 In-house 22-114 (151) alignment 
Range on Protein: 51-140
Range on HMM: 22-114/151.0
DVQRFFNTLHADHYKVYNLCSERKYEHCRFED---RVSEYPFDDHCPPTLNIISEFCNDMEMWLDQNPENVVAVHCKAGKGRTGTMLACWLLY
 ...| ..|.  . |    . | .|.   .|.   .| ...|||  .|. ... |. . ...   ..|...||||| || ||.  ..|  |. 
tlekfieelkkeevktvvrvceptydteklekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalalie
subfamily_PTPMT1_pd Subfamily PTPMT1 64-161 1.2e-10 36.2 In-house 57-151 (171) alignment 
Range on Protein: 64-161
Range on HMM: 57-151/171.0
YKVYNLC-SERKYEHCRFEdrVSEYPFDDHC-PPTLNIISEFCNDMEMWldQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTgSESMRLFANKRTHN
|..  |. | .....   |    ...  |.   |.|. ...  . .|    ..  . | ||||||.||..|. ||.|........  | ..  ..|| . 
yelkalansteewkklgve..qlqlatvDfteapdleklekgvefiekv..askgkrvYvHCkaGrgRsatlvacylmkkeklsp.eeAlkalkkkRkii
0051429 (Phosphotyrosine protein) phosphatases II 47-144 3.8e-10 35.4 In-house 44-178 (272) alignment 
Range on Protein: 47-144
Range on HMM: 44-178/272.0
NRMRDVQRFFNTLHADHYKVYNLCSERKYEHCRFEDRVSEYPF--------------------------------------------DDHCPPTlniiSE
.. . .  . ..   ...|.. .    .| |. ..|.. . ..                                             ||. |.    ..
lgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpq....ea

FCNDMEMWLDqnpENVVAVHCKAGKGRTGTMLACWLLYNKQC
... .|. ||   .. | |||.|||.||||. |..||.   .
llellellld...ggpvlvHCsaGkdRTGtvvallllllgvs
PTPc_DSPc_SM00012 90-147 6.2e-10 34.6 In-house 12-70 (105) alignment 
Range on Protein: 90-147
Range on HMM: 12-70/105.0
DDHCPPTLNIISEFCNDMEMWLDQNP-ENVVAVHCKAGKGRTGTMLACWLLYNKQCQTG
| ..| . . | |...... .  ..  .. | |||.|| |||||. |  .|... ... 
dhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket
DSPc Dual specificity phosphatase, catalytic domain 73-165 4.5e-09 31.3 Pfam-A 40-121 (133) alignment 
Range on Protein: 73-165
Range on HMM: 40-121/133.0
RKYEHCRFEDrvseyPFDDHCPPTLNIISEFCNDMemwldQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCqTGSESMRLFANKRTHNSKGV
..| ..  ||       ..   . |. ..|| ...     .. .. |.|||.||  |..|. ...|.. |.. . .| .... ..| . |. .
ieylripved.....etetkiskeleeavefieka.....eqkgkkvlVHCqaGisRSatliiaYlmktknl.slneAyefvkerrskispna
DSPc Dual specificity phosphatase, catalytic domain 73-165 4.5e-09 31.3 In-house 40-121 (133) alignment 
Range on Protein: 73-165
Range on HMM: 40-121/133.0
RKYEHCRFEDrvseyPFDDHCPPTLNIISEFCNDMemwldQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCqTGSESMRLFANKRTHNSKGV
..| ..  ||       ..   . |. ..|| ...     .. .. |.|||.||  |..|. ...|.. |.. . .| .... ..| . |. .
ieylripved.....etetkiskeleeavefieka.....eqkgkkvlVHCqaGisRSatliiaYlmktknl.slneAyefvkerrskispna
subfamily_RNGTT_pd Subfamily RNGTT 95-159 4.6e-09 30.2 In-house 92-155 (189) alignment 
Range on Protein: 95-159
Range on HMM: 92-155/189.0
PTLNIISEFCNDMEMWLDQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTgSESMRLFANKRT
|. . ..|| . .| . ..|||.|..|||. |  ||| .....|. .....  .....|||. | 
PeaeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedwsv.eaavalFakaRp
LIM LIM domain 768-818 4.8e-09 24.3 Pfam-A 1-53 (58) alignment 
Range on Protein: 768-818
Range on HMM: 1-53/58.0
CDQCNQYIDGMFL--KVNGKNLCPTCFRCFCCNEVLEGGKYFEKNGESICEKC
| .||..|    |  |..||.  . ||.|  |.. |. ...|||.|.  |.|.
CagCnkkiadrelvlkalgkvyHeeCFtCseCqkplkeksffekdgklyCkkd
LIM LIM domain 503-546 5.9e-09 24.0 Pfam-A 1-45 (58) alignment 
Range on Protein: 503-546
Range on HMM: 1-45/58.0
CSGCNLVIKTSDFE-ELGDHIYHRSCFLCYYCTSYLGGKDFIVEN
|.|||  |. ..   .  .. ||..|| |  |   |. |.|.. .
CagCnkkiadrelvlkalgkvyHeeCFtCseCqkplkeksffekd
PTPc_motif_SM00404 85-162 1.7e-08 29.5 In-house 58-125 (140) alignment 
Range on Protein: 85-162
Range on HMM: 58-125/140.0
SEYPFDDHCPPTLNIISEFcndmemwldQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQTgSESMRLFANKRTHNS
 . .. .. . .|..|...         .. .  | |||.||  |..|. ...|.. .|... .|..... ..| . |
ekdklskyldkvldfiena.........ekkggkvlVHCqaGvSRSatliiaYlmryrqlsl.aeayefvkerRpiis
LIM LIM domain 641-694 2.1e-08 22.2 Pfam-A 1-53 (58) alignment 
Range on Protein: 641-694
Range on HMM: 1-53/58.0
CSKCELAINQSRPII-LDCGIYHRECFQCSECfdETPMDPSLYYIRNDKPVCFDC
|..|.  |...  ..      ||.|||.||||  ..|.... ......|..| ..
CagCnkkiadrelvlkalgkvyHeeCFtCseC..qkplkeksffekdgklyCkkd
Y_phosphatase Protein-tyrosine phosphatase 74-162 4.2e-07 25.0 Pfam-A 134-217 (235) alignment 
Range on Protein: 74-162
Range on HMM: 134-217/235.0
KYEHCRFEdrvsEYPfDDHCPPTLNIISEFCNDMEMWLdQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQT-GSESMRLFANKRTHNS
. ..  ..    . | |  .| . . . ......| .  .. .. | |||.|| |||||..| ..| ..  ..   . . .  . |..  
evkqlhyt....nWp.dhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRp
Y_phosphatase Protein-tyrosine phosphatase 74-162 4.2e-07 25.0 In-house 134-217 (235) alignment 
Range on Protein: 74-162
Range on HMM: 134-217/235.0
KYEHCRFEdrvsEYPfDDHCPPTLNIISEFCNDMEMWLdQNPENVVAVHCKAGKGRTGTMLACWLLYNKQCQT-GSESMRLFANKRTHNS
. ..  ..    . | |  .| . . . ......| .  .. .. | |||.|| |||||..| ..| ..  ..   . . .  . |..  
evkqlhyt....nWp.dhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRp
subfamily_DSP11_pd Subfamily DSP11 92-161 4.3e-07 24.0 In-house 90-160 (178) alignment 
Range on Protein: 92-161
Range on HMM: 90-160/178.0
HCPPTLNIISEFCNDMEMWLD--QNPENVVAVHCKAGKGRTGTMLaCWLLYNKQCQTGSESMRLFANKRTHN
|  |. .....|.. .. .|.  .. .....|||  |  ||| .. |  | ...    ..... | . | |.
hevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyli.CrylidvegyepedaieafeearGhs
subfamily_PTPN6_pd Subfamily PTPN6 87-181 3.1e-06 21.4 In-house 196-294 (306) alignment 
Range on Protein: 87-181
Range on HMM: 196-294/306.0
YPfDDHCPPTLNIISEFCNDMEMWLDQNP---ENVVAVHCKAGKGRTGTMLACWLLYNKQCQTGSES----MRLFANKRTHNSKGVTIPSQIRYVryFEA
.| |  .|   . . .| .|...  ..     .  . ||| || |||||..   .| ..  ..| .      .|    |.. |  | . .| ..|  ..|
WP.dhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfv..yka

LL
. 
ik
subfamily_pats1_pd Subfamily pats1 340-432 3.9e-06 17.5 In-house 205-301 (691) alignment 
Range on Protein: 340-432
Range on HMM: 205-301/691.0
ATGLAKLYHNSNSNNKSLTSSTSSTSNLSSSTN--NTFEIISN-------NNNNNNNNNNNNNINSNNNKINDENSNKNNNNNNiiNNNsfsAWGNNSKI
   | .|. | . . .| .||. |||. ||| |  . |. | .       |...||||||||| |||||  |..| | ||||||  |||     ..||||
dvklynlfvnkeeqlqsssssslstslnsssnnlnkefqqihqqmqqnqlnsssnnnnnnnnnnnsnnnnnnnnnnnnnnnnnn..nnn...nnnsnski

VK
 |
nk
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 118-185 4e-06 20.7 In-house 218-284 (290) alignment 
Range on Protein: 118-185
Range on HMM: 218-284/290.0
VVAVHCKAGKGRTGTMLACWLlyNKQCQTGSESMRLFANKRT-HNSKGVTIPSQIRYVRYFEALLQYGK
 |.||| || |||||. |       |. .   ...|    |.  ||.  ..  .|.|.   |.||..||
pvvvhcsaGiGrtGtfvaiev..glqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGk