Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| DSPc_SM00195 | 27-348 | 1.1e-97 | 321.9 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 27-348
Range on HMM: 2-262/263.0
IDKEFNFILQKTELRaletdKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssd
...||. ....|. . ....| . ||| ||||.|.||...||||.. ....
lkeefekleestspk.....etteaekkknksknRyknilpydhtrVklkkeekk.............................................
eedhggsgdegtTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKFDNNITIP
. ||||||..|. .||.||||| .|. |||.|.||....||||||.|||| |.|||.|||.. ..|..|.. ||. .... .
............egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkk
DILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR--SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDekkqapsINLPK
| .|.|...|.. ....|||....||..|||||.| ||. .|.....|...|. |||||||||||.||.||||.|..|. |.... . ... .
deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekk.......vdife
LVVEMRNERPGMVQTRDQYRFCYLAISEAM
.| |.|..|||||||..||.|.| || |..
ivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 27-348 | 1.1e-97 | 321.9 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 27-348
Range on HMM: 2-262/263.0
IDKEFNFILQKTELRaletdKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssd
...||. ....|. . ....| . ||| ||||.|.||...||||.. ....
lkeefekleestspk.....etteaekkknksknRyknilpydhtrVklkkeekk.............................................
eedhggsgdegtTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKFDNNITIP
. ||||||..|. .||.||||| .|. |||.|.||....||||||.|||| |.|||.|||.. ..|..|.. ||. .... .
............egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkk
DILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR--SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDekkqapsINLPK
| .|.|...|.. ....|||....||..|||||.| ||. .|.....|...|. |||||||||||.||.||||.|..|. |.... . ... .
deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekk.......vdife
LVVEMRNERPGMVQTRDQYRFCYLAISEAM
.| |.|..|||||||..||.|.| || |..
ivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 22-353 | 5.6e-88 | 290.5 | In-house | 39-304 (308) | alignment | ||
Range on Protein: 22-353
Range on HMM: 39-304/308.0
NHPTCIDKEFNFILQKTElraleTDKFRSALEAKNKLKNRYSNVLPFEETRVKIniddD-Dddeddneddiivsnnnnnnnnnekrikrnsigssgqsdv
. .. ...||. .|.... ....|| .|| ||||...||.. .|||. | .
ldlglleeefeellsvkp.....lleysvallpenkdkNrykdilpydhsRVkl....deg.......................................
msnssdeedhggsgdegttlSDYINASFINNG------TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK---DEERYGNFIV
|||||||... ..|.||||| ||. |||.|.||||...|||||...|| . ||..|||.. . ..||.| |
....................sdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftv
KFDNNITiPDILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekkqa
.. . . | ..|...|.||.|...|...||.||.|||||.| |.. .|.|. .|.. ..||||||||||.||.|||.|. .. . |.
tllseev.lddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqleke.......
PSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMNTVLK
......| .| ||||||| .||.|.| |. | ....|.
ggvdvfeavkklReqRpgmvqtpeqylflyralleylklklt
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 25-372 | 1.7e-81 | 269.3 | In-house | 18-300 (317) | alignment | ||
Range on Protein: 25-372
Range on HMM: 18-300/317.0
TCIDKEFNFILQKtelralETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsns
| . .||. .|. | .. |. .|| ||||...||.. .|||..
talleefedllsl......kldtysvaelpenkdknrypdilpydhsRVkLsp...............................................
sdeedhggsgDEGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITiP
..| |||||||... . ..|.||||| ||. |||.|.|||....|||||..||. . ||..|||.... ||.|.|.. . ..
..........lggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee.l
DILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE--KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkqapSINLPK
. . |....|.|.|...|...||.||.|||||.| |.. .|.|...|.. ...||..||||||.||.|||.|. .. . |.. .....
agitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeg.......gvdvee
LVVEMRNERPGMVQTRDQYRFCYLAISEAMNTVLKKEQKKRKGLSYSYSSIPLT
| |.|. |||.||| .||||.| |. | ....|..| ... | . . |||.
avkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllkllipla
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 25-351 | 2.2e-81 | 268.7 | In-house | 13-280 (297) | alignment | ||
Range on Protein: 25-351
Range on HMM: 13-280/297.0
TCIDKEFNFIlqkteLRALETDKFRSALEAKNKLKNRYSNVLPFEETRVKIniddD--Dddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvms
... ||| . |. | ... || .|. ||||...||.. ||||. | .
alllkefeel.....lpllllgslsvallpenleknRykdilpydhtRVkl....ddeg.........................................
nssdeedhggsgdegttlSDYINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKFDNN
|||||||... ..|.||||| ||. |||.|.||||...|||||...|. . ||..|||.. .. ||.|.|.. .
..................sdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsv
ITI-PDILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekKQA
.. | ..|............|...||.||.|||||.| |.. .|.|. .|.. ..||..||||||.||||||.|. .. . .. .
evvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledk....lke
PSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMNTV
. ......| ..|. |||.||| .||||.| |. | ...
ggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 17-346 | 2.7e-81 | 268.5 | In-house | 15-284 (288) | alignment | ||
Range on Protein: 17-346
Range on HMM: 15-284/288.0
IEHFNNHPTCIDKEFNFILQKTELraletDKFRSALEAKNKLKNRYSNVLPFEETRVKINiddddddeddneddiivsnnnnnnnnnekrikrnsigssg
.. |..| . .||. .|.... ....|| .|. |||||..||.. .|||..
lkllangltglleefeellsllpd.....ltlsaallpenleknRysdilpydhsRVkLs........................................
qsdvmsnssdeedhggsGDEGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVK
.| |||||||.|. . ..|.||||| ||. |||.|.||||...|||||...|. ..||..|||... . ||.. |.
.................vldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvt
FDNNITiPDILIRREFTLENL----KDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE--KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYd
. . . | . |.....|| .|...|...||.||.|||||.| |.. .|.|. .|.. ...||.|||||||.||.|||.|. .. . |..
llseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeg.
ekkqapSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISE
......| .|. ||||||| .||||.| |. |
......gvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 136-351 | 8e-80 | 264.0 | In-house | 71-284 (564) | alignment | ||
Range on Protein: 136-351
Range on HMM: 71-284/564.0
EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIrREFTLE
||. |||||||||. . .|| ||||| .|| |||.|.|||||..|||||. ||. |.||.||||.|..|.||...|.. .. .. |. | |.|.|.
egdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyei.rtfklk
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH--EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydEKkqapSINLPKLVVEMRNERPG
. |....|.. .|..| ||||| | |.|..|.... | . |. .||||||||||.||.|||..|.... . . || ... . | ..|..|.
kkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerike...ek....tvDiyqyvkalrkqRna
MVQTRDQYRFCYLAISEAMNTV
||||..|| |.. || ||..
mVqteeQYiFiheailealacg
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 22-346 | 4.8e-78 | 257.7 | In-house | 9-270 (273) | alignment | ||
Range on Protein: 22-346
Range on HMM: 9-270/273.0
NHPTCIDKEFNFILQKTElraleTDKFRSALEAKNKLKNRYSNVLPFEETRVKIniDDDDDDeddneddiivsnnnnnnnnnekrikrnsigssgqsdvm
...|.. .||. .|. .. ... || .|| ||||...||.. .|||. .|...|
lgltllleefelllslkp.....lltysvallpenkdknrykdilpydhsrvkl..gdggsd......................................
snssdeedhggsgdegttlsdYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD---EERYGNFIVKFD
|||||... . ..|.||||| ||. |||.|.||||...|||||...|. . ||..|||.. ...||.|.|..
.....................yinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtll
NNITiPDILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH----EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkq
. | | . |...|.||.....|...||.||.|||||.| |.. .|.|. .|.. ...||.|||||||.||.|||.|.. .. . |..
seet.kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeg.....
apSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISE
......| .|. ||||||| .||||.| |. |
..gvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 21-349 | 2.2e-76 | 252.4 | In-house | 28-290 (297) | alignment | ||
Range on Protein: 21-349
Range on HMM: 28-290/297.0
NNHPTCIDKEFNFILQKTElraletDkFRSALEAKNKLKNRYSNVLPFEETRVKINIDDddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdv
| .|....|| .|. .. | .. || .|| ||||...||.. .|||.. |
ansktllllefeellslkp......d.ysiallpenkdknrykdilpydhsrvklkped.........................................
msnssdeedhggsgdeGT-TLSDYINASFIN-----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKtKCDKYWPDKDEeRYGNFIVKFD
|. |||||||... . ..|.||||| .|. |||.|.|||....|||||...|. . ||..|||.. . .||.| |..
................gvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtll
NNITiPDILIRREFTLENlkDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekkq
. .. | ..|.....| ....|...||||| |||||.| |.. .|.|. .|.. ..||..||||||.||.|||.|. .. . |.
kveh.ldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqleke......
aPSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMN
..... | |.|. |||.||| .||||.| |. | .
.ggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 56-345 | 2.9e-76 | 251.4 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 56-345
Range on HMM: 1-234/235.0
NKLKNRYSNVLPFEETRVKIniddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgDEGTTLSDYINASFI----NN
|| ||||...||...||||. .. .. ||||||... ..
nkkknRykdilpydktrvkl...........................................................kgsegpsdYInAnyvkgykek
GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWP--DKDEERYGNFIVKFD-NNITIPDILIRREFTLENLKDNK-TRKIYHFQYT
..|.||||| .|| |||.|.|......|||||..||. ..||..||| ......||.. |. .. .. . . |...|.. |... .|......||
kkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhyt
TWPDHGTPVSTTGFLKFVSFVDHEK--RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydEKKqapsINLPKLVVEMRNERPGMVQTRDQYRFCYLAIS
.|||||.| |....|... | ..| .|||.|||||||.||.|||||. .. .. . |.. ... ..| |.|..||||||. .|| |.| ||
nWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqlea...eee....vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 56-345 | 2.9e-76 | 251.4 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 56-345
Range on HMM: 1-234/235.0
NKLKNRYSNVLPFEETRVKIniddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgDEGTTLSDYINASFI----NN
|| ||||...||...||||. .. .. ||||||... ..
nkkknRykdilpydktrvkl...........................................................kgsegpsdYInAnyvkgykek
GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWP--DKDEERYGNFIVKFD-NNITIPDILIRREFTLENLKDNK-TRKIYHFQYT
..|.||||| .|| |||.|.|......|||||..||. ..||..||| ......||.. |. .. .. . . |...|.. |... .|......||
kkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhyt
TWPDHGTPVSTTGFLKFVSFVDHEK--RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydEKKqapsINLPKLVVEMRNERPGMVQTRDQYRFCYLAIS
.|||||.| |....|... | ..| .|||.|||||||.||.|||||. .. .. . |.. ... ..| |.|..||||||. .|| |.| ||
nWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqlea...eee....vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 26-345 | 1.4e-75 | 249.7 | In-house | 21-274 (278) | alignment | ||
Range on Protein: 26-345
Range on HMM: 21-274/278.0
CIDKEFNFILQKTElraletDKFRSALEAKNKLKNRYSNVLPFEETRVKINIddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnss
.. .|| .|. . | .. || .|| ||||...||.. .|||..
llllefeellsfkl......dtysiallpenkdknrykdilpydhsrvklsl................................................
deedhggsgDEGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPdKDEERYGNFIVKFDNNITiPD
..| |||||||... . ..|.||||| .|. |||.|.||.....|||||...|. ..||..||| .. ..||.| |.. . .. |
.........lggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeeh.ld
ILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE--KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkqapSINLPKL
..| ....||.|...|...|..|. |||||.| |.. .|.|. .|.. ...||..||||||.||.|||.|. .. . |.. ..|..
dytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeg.......gvdleea
VVEMRNERPGMVQTRDQYRFCYLAIS
| |.|. |||.||| .||||.| |.
vkelreqRpgavqtpsqyrflyeall
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 17-346 | 1.9e-75 | 249.7 | In-house | 19-302 (307) | alignment | ||
Range on Protein: 17-346
Range on HMM: 19-302/307.0
IEHFNNHPTCIDKEFNFILQKTELRaleTDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDneddiivsnnnnnnnnnekrikrnsigssg
. ...| . |||. .|. | .....|| .|| ||||...||.. ||||.. |......|
llllldfltgllkefekllsvtvfl...lgeysiallpenkdknrykdilpydhtRVklssldgsledsd..............................
qsdvmsnssdeedhggsgdegttlsdYINASFI------------NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE
|||||.. .. ..|.||||| .|. |||.|.|||....|||||...|. . ||..||||..||
..........................YiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegee
-RYGNFIVKFDNNITiPDILIRREFTLENL-KDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH--EK--RSGPIVVHCSAGIGRSGTFVAIHSIV
|||| |.. . . | ...| .....| .....|...||.||.|||||.| |. .|.|. |.. |. ..||..||||||.||.|||.|. .
ltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylml
AKFAKHydekKQAPSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISE
. |. . . ..|.. | ..|. |||.||. .||||.| |. |
rqleke....gtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 46-347 | 3e-75 | 248.4 | In-house | 23-271 (278) | alignment | ||
Range on Protein: 46-347
Range on HMM: 23-271/278.0
DKFRSALEAKNKLKNRYSNVLPFEETRVKiniddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegttlsDYIN
... || .|. ||||...||.. .||| ||||
seitpalylgnldknRykdilpydhsrVk...................................................................dYIN
ASFIN--NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIpDILIRREFTLENL----KDNKTR
||.|. . ..|.||||| .|. |||.|.||.....|||||...|. . ||..|||... ..||.| |.. . .. | . | ....|| .|...|
AsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevl.ddytlrtllvtnltveredlesr
KIYHFQYTTWPDHGTPVST--TGFLKFVSFVDHEK---------------RSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKqaPSINLPKLVVE
...|..|..|||||.| .. . ||... |... ..||..||||||.||.||.||.. . . . . ..|.. | |
gvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell.......e..ggvdlleavke
MRNERPG-MVQTRDQYRFCYLAISEA
.|. ||| .||. .||||.| .. |
lrsqRpglavqnleqyrflyefllel
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 138-352 | 1.2e-74 | 246.5 | In-house | 54-278 (284) | alignment | ||
Range on Protein: 138-352
Range on HMM: 54-278/284.0
TTLSDYINASFINNG---------TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVKFDNNITiPDILIRRE
. |||||||... ..|.||||| ||. |||.|.||||...|||||...|| ..||..|||... .||.|.|.. . . | ..|.
ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseev.kddytvrt
FTLENLK-DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE----KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekKQAPSINLPKLVVE
..|.||. ....|...||.||.|||||.| |.. .|.|. .|.. ...||||||||||.||.|||.|.. . . |. .. ......|
leltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqleke....glllgvdvleavkr
MRNERPGMVQTRDQYRFCYLAISEAMNTVL
.|. ||||||| .||||.| |. |.....|
lreqRpgmvqtleqyrfvyealleylklkl
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 49-346 | 1.4e-71 | 236.3 | In-house | 4-244 (249) | alignment | ||
Range on Protein: 49-346
Range on HMM: 4-244/249.0
RSALEAKNKLKNRYSNVLPFEETRVKINIddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgDEGTTLSDYINASF
. || .|| ||||...||.. .|||..| .| ||||||||.
svallpenkdknrypdilpydhsrvklsi.........................................................lpglflsdyinAsy
IN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDiLIRREFTLENLKDNKTRKIYHF
|. . ..|.||||| .|. |||.|.||.....|||||...|. . ||..|||.... ||.| |.. . .. .| ...|...|.||.|...|...|.
idgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkdd.ytvrtleltnlydgesrtvlhi
QYTTWPDHGTPVSTTGFLKFVSFVDHEK----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDekkqapsINLPKLVVEMRNERPGMVQTRDQYRFC
||| |||||.| |. .|.|. |.. ..||..||||||.||.|||.|. .. . |... ..|. | ..|. |||.||. .||||.
qytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelg.......vdleeavkllrsqRpgavqnpeqyrfl
YLAISE
| |. |
yealle
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 35-352 | 6e-71 | 233.8 | In-house | 19-280 (281) | alignment | ||
Range on Protein: 35-352
Range on HMM: 19-280/281.0
LQKTELRALETDKFRSALE-AKNKLKNRYSNVLPFEETRVKINIDDDDDdeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggs
. ..|.|...|. .| . .|.|||||||. .. ||||.. ....
eeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk...................................................
gdegttLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVKFDNNITIPDiLIRREF
.|||||.|.. . || ||||. ...|.||.|.|||. ..|||.||| |. | || .||||.. | .||...||. .. . . |.|.|
......ntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekat.yierkf
TLeNLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV--DHEKR-SGPIVVHCSAGIGRSGTFVAIHSIVAKFAkhydekKQAPSINLPKLVVEMRN
.| . ....||.. ...||.||||| | .|. .|.| . | .||. |.|.|||||.||.||..|. .| . . ........ .| |.|.
kl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkave......aeleeldvkavvaelrk
ERPGMVQTRDQYRFCYLAISEAMNTVL
|| |||| ||.| |.|. .|.. |
ernlmvqtvvqyefvykavldaldkel
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 50-346 | 1.5e-70 | 232.7 | In-house | 3-241 (245) | alignment | ||
Range on Protein: 50-346
Range on HMM: 3-241/245.0
SALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDdneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegttlsdYINASFI
.|| .|| |||||..||.. ||||.. |. | | | |||||..
vallpenkdknrysdilpydhtrvklspdggdldsd.........................................................yinasyv
----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITiPDILIRREFTLENLKDNKTRKIYHFQ
....|.||||| .|. |||.|.||.....|||||.|||. . ||..|||.... .||.|.|.. . . | ...|.....||.|...|...|..
dgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseeh.lddytvrtlevtnlgddesrevihyh
YTTWPDHGTPVSTTGFLKFVSFVDH---EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkqapSINLPKLVVEMRNERPGMVQTRDQYRFCYL
|. |||||.| .. .|.|..||.. |...||..||||||.||.|||.|. .. . |.. ..|.. | |.|. |||.||| .||||.|
ylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekel.......gvsleeavkelrsqRpgavqtpsqyrflye
AISE
|. |
alle
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 136-352 | 1.5e-69 | 229.5 | In-house | 69-284 (318) | alignment | ||
Range on Protein: 136-352
Range on HMM: 69-284/318.0
EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIrREFTLE
||.. ||||||..|. . .|| .|.|| .|| |||.|.||||| .|||||.|||. |.|...|||.|. . ||. |. ...... | .. |||...
egeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvl.refkvt
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH---EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERP
. . ...|.. ..||.|||.|.| |....|..| |.. .. ||||||||||.|| |.|.|. ... . |. ... . | ..|..|.
rteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdilleri.......kaealvDvfqtvkqlreqrn
GMVQTRDQYRFCYLAISEAMNTVL
||||.||| |.| .. ||...
lmvqtedqyefiydvllealasgd
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 49-346 | 4.4e-69 | 228.0 | In-house | 3-240 (243) | alignment | ||
Range on Protein: 49-346
Range on HMM: 3-240/243.0
RSALEAKNKLKNRYSNVLPFEETRVKIniddddD-DeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegttlsDYINAS
. || |. |||||..||.. .|||. . . |||||.
siallpenlsknrysdilpydhsrvkl......egs..........................................................dyinan
FIN-NGTYICTQGPLLNTIVD----FWKMIWEQNSNIIVMLTREEENFKTKCDKYWPdkDEERYGNFIVKFDNNITIPDiLIRREFTLENLK-DNKTRKI
.|. ...|.||||| .|. | ||.|.||.....|||||...|. . ||..||| .|..||.|.|.. . . .| . |...||||. |. || .
liyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gevtygdftvtllseehldd.ytvrtlllenldlddltrlv
YHFQYTTWPDHGTPVSTTGFLKFVSFVD----------HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekkqapSINLPKLVVEMRNERPG-M
.|..|. |||||.| |.. .|.|...| .....||..||||||.||.||..|. . .. ...| . | ..|. ||| .
ihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...........gvdleeavkllreqRpgka
VQTRDQYRFCYLAISE
|||..||||.| |. |
vqtpsqyrflyealle
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 136-350 | 5e-65 | 214.5 | In-house | 76-299 (306) | alignment | ||
Range on Protein: 136-350
Range on HMM: 76-299/306.0
EGTTLSDYINASFIN------NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVKFDNNITIPDIlIRREF
.... ||||||..|. . .|| ||| | .|. |||.|.|..||..|||.|.| | | || .||||. .|.||. |. .. . | | ||.
psvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladY.ilRel
TLE-NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK------RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAkhydEKKQAPSINLPKLVV
... . |....|.........|||||.| .. .|.|.. |.... ..||||||||||||| |||. | .. . .|. |.. |||
svskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillklie....kkgldadidiqklvk
EMRNERPGMVQTRDQYRFCYLAISEAMNT
.|. | |.||| .||.| | ||.. ..|
svreqrsglvqteqqykfvykaikkyiet
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 137-350 | 5.4e-65 | 214.6 | In-house | 80-292 (298) | alignment | ||
Range on Protein: 137-350
Range on HMM: 80-292/298.0
GTTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIrREFTLEN
. ||||||||... ..| ||.|| .|..|||.|..|.... ||||| || |||. |||||. .|.||.. |. .. . |. . |......
adeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadliv.rklkvsk
LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH-EKRSG--PIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPG
| .|.|.. ....|.|||.|.| .| |.... | ....| |..|.||||.||||||.||.|.. . |. .. . . | .|..|||
kkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlerv.......kkeqvvDvfqvvkvlRkkrpg
MVQTRDQYRFCYLAISEAMNT
.|||..|| |.| |. ||...
avqteeqYvfiyeavlealds
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 138-350 | 3.7e-64 | 211.6 | In-house | 76-287 (293) | alignment | ||
Range on Protein: 138-350
Range on HMM: 76-287/293.0
TTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK-DEERYGNFIVKFDNNITIPDILIrREFTLEN
.. ||||||..|.. .| ||||| .|. |||.|.||..|.||||||. |. |.||..|||.. .. ||. |.. .. . | | ||...|.
esgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvi.relkiek
lkDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydekkqAPSINLPKLVVEMRNERP
....||. ....|.||||| | .|. .|.|| |.... ...|||||||||.||.|||.|.. .. . . ... .|.|.|.||
..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaiee.......edyvdifgivaelReeRn
GMVQTRDQYRFCYLAISEAMNT
.||| .|| | . .. . ...
llvqtekqYifihqcvldllrk
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 138-357 | 7.5e-64 | 210.4 | In-house | 65-287 (290) | alignment | ||
Range on Protein: 138-357
Range on HMM: 65-287/290.0
TTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEER--YGNFIVKFDNNITIP-DILIRrefTL
. ||||||.||.. .|| .|||| .|. |||.||||.| .|.||. || |. |.||..|||.. ||. .|.| |. ... .. |.||| ||
eegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflir...tL
ENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVD--HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydeKKQAPSINLPKLVVEMRNERP
. .....||.| |.|| |||||.| |.. |.... | .|. . |.|||||||.|| || .|| . . . .| ...... .||.|.|..|.
kveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellka....ekipeeldvfdlvlelrkqra
GMVQTRDQYRFCYLAISEAMNTVLKK-EQK
.|||..||.. | |. | ... |. |.|
alvqtkeqyelvykavaelvqkeleiieek
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 135-350 | 7.2e-63 | 207.6 | In-house | 68-285 (305) | alignment | ||
Range on Protein: 135-350
Range on HMM: 68-285/305.0
DEGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDNNITIPDILIRrEF
.| . |||||||... . .|| .|||| ||..|||..|.| . |||||. |. | || .|||.. | ..|.|.|. .. |..| ..| ..
keslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieR.kl
TLEN-LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRSG---PIVVHCSAGIGRSGTFVAIHSIVakfakhyDEKKQAPSINLPKLVVEMR
.. . .|...| . ..| |.||||| | ..| .|... | ...... |..||||||.||.|.|.|.. . . |. .... ... ..|
kisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdial.......erlkkEevvdvfevlkqlR
NERPGMVQTRDQYRFCYLAISEAMNT
..|..|||| ||| |.. |. | ...
skrmkmvqtldqYvflhdaldelitc
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 138-347 | 1.6e-62 | 206.2 | In-house | 72-278 (288) | alignment | ||
Range on Protein: 138-347
Range on HMM: 72-278/288.0
TTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE-ERYGNFIVKFDNNITIPDIlIRREFTLEn
.. .||||||.|.. .||.||||| .|. |||....|.... ||||| |. ||||..||||.|. ..||.. |. .. . |. . |.. ||
eagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledf.vlrkllle.
lKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK--RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydekkqAPSINLPKLVVEMRNERPGM
|... ..| ..||..||||| | |.. .|.... |. . .|||.||||||.||.|||.|.. .. . . |.. | ..|..|. .
.kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidavee.......edyiDvagtvaklRkqRall
VQTRDQYRFCYLAISEA
||| || |.| .. .
vqtlkqYefiyevllsl
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 137-350 | 4.8e-62 | 204.9 | In-house | 72-285 (319) | alignment | ||
Range on Protein: 137-350
Range on HMM: 72-285/319.0
GTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIrREFTLEN
|. |||||||||. . .| ||.|| ||| |||.|.||..| |.||||. |. | |. ||||... |.||..||. ... |. | |...|..
gvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyii.rklklnk
LKDNK-TRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK---RSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERP
.... ||.. ||||| ||||. | ..|. |... . . . |||||||||||.|| |||.... .. . |. ... . | ..| |.
kssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlerv.......keegvlDvfstvsrlRtqRn
GMVQTRDQYRFCYLAISEAMNT
|||. .||.|.| |. ||...
imvqrpeqYkfiyealleavea
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 137-349 | 1.6e-61 | 203.1 | In-house | 72-287 (307) | alignment | ||
Range on Protein: 137-349
Range on HMM: 72-287/307.0
GTTLSDYINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDIlIRREFTLEN
|. |||||||||. ..|. |.|. .|| |||.||.||....||||. ..| . ||.||||. || .||. .||. .. . .| |.||. . .
gkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdy.iiReldvsk
LKD-----NKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV-D-HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydEKkqapSINLPKLVVEMRN
|. ...||. ..||.|.| | ...| ||... | . ... .||||||||| ||||.|||. |.. . . |. .... . | ..|.
kkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlka...ed....kvdifetvkdLrs
ERPGMVQTRDQYRFCYLAISEAMN
.|. .|| .|| |.| |. . ..
qRnllvqsleqYvflyralldyss
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 56-350 | 2.8e-61 | 202.0 | In-house | 28-270 (274) | alignment | ||
Range on Protein: 56-350
Range on HMM: 28-270/274.0
NKLKNRYSNVLPFEETRVKINIDDDDddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegTTLSDYINASFIN-----
.. |||| ..|| |..|| .. .. . .|.|||| .|
sqtknryktilPnensrvllesesse........................................................dedssyinanyikGydee
NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE----RYGNFIVKFDNNITIPDILIRrEFTLENLKDnkTRKIYHFQY
. .|. ||||| ||. |||.||.......|||||. .|. ..|| .|.||. . |||.. .|... .. | .| ...|..|.. .|...|. |
skayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvr.klvlkyler..ersvkhywy
TTWPDHGTPVSTTGFLKFVSFVDHEK-----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydekkqAPSINLPKLVVEMRNERPGMVQTRDQYRFCY
| |||| .| ... .|..| |.... . .|.|||||||||| | |.||. | .. . ... |.|...| .| |||||..||.. .
tdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlre.......eivvdvlkivcnlrldrGGmvqtseqyelih
LAISEAMNT
|... ..
ralclylkr
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 136-347 | 5.6e-61 | 201.2 | In-house | 81-294 (330) | alignment | ||
Range on Protein: 136-347
Range on HMM: 81-294/330.0
EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIRrEFTLE
||. |||||||||. ..| .|||. .|. |||.|||||.| ||||| .| ..|| .||||. ||| |. ... . |. .| .| ..
eGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvr.kflvq
N----LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE--KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhYDEKKqapsINLPKLVVEMRN
. ...|.| . | .|.||| | |. . | ||.. | . . .||||||||||.||.|||... ..... |.| ... . | ..|.
qlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlerv...kaerk....vdvfefvkrlrl
ERPGMVQTRDQYRFCYLAISEA
|| |||| || |.| .. |
qrpqmvqtdeqyefiykvlley
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 141-351 | 1.7e-60 | 199.6 | In-house | 60-272 (273) | alignment | ||
Range on Protein: 141-351
Range on HMM: 60-272/273.0
SDYINASFIN------NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEER---YGNFIVKFDNNITIpDILIRREFTLE
. |||||.|. . .|| .|||| .|. |||.|.|||....|.|.| | |. | ||..|||.. ... .. . |. . | . |.....
ggyinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkl.dgfvvralavk
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR-SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkqapSINLPKLVVEMRNERPGM
... ...|.. |.....|||||.| |.. .|.||. | . .. .||||||||||||||||...|. .. .. .... ..| ..|. | |.
dsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdk.......efdvkeivrklreqrqgv
VQTRDQYRFCYLAISEAMNTV
|||.||| |.| || |.....
vqtkdqyifvykailevlksl
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 141-355 | 2.7e-60 | 198.5 | In-house | 56-278 (290) | alignment | ||
Range on Protein: 141-355
Range on HMM: 56-278/290.0
SDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYG-----NFIVKFDNnITIPDILIRREFTLE
||||||... . || ||||| ||. ||.|.|||.| .||| . |. ..|| .||| ..||. .. ||. . . . ..| . ||
ndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvklis.eerksyytvrllele
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH----EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhyDEKKQAPSINLPKLVVEMRNER
||| ..||.|.|| |||||| | | | . ||||. | . . || |.||||||||||||. . ..... ..|... |... | ..|.|. |
nlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvli....ekkddlssvdikkvllelrkyr
PGMVQTRDQYRFCYLAISEAMNTVLKKE
|..|| || || |||| | .... ..
lGliqtadqlrfsylaileGakvikgds
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 134-350 | 5.2e-60 | 198.2 | In-house | 71-289 (563) | alignment | ||
Range on Protein: 134-350
Range on HMM: 71-289/563.0
GDEGTTlsDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIP----DILIR
| ... |||||..|. . .| ||||| .|. |||.||||||..||||.| .|. . ||| ||| . |.||.. |. .. .. |.
gkkkkl..DYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlvi
REFTLENLKD-NKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRS--GPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVE
... |.. |. .. .......||.|||||.| ... |.|| . ... ||||||||||.||.||.... ... . .| ..|. ...
knlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqi.......qqenavnvfgflkh
MRNERPGMVQTRDQYRFCYLAISEAMNT
.| .|. .|||..|| | . |. ||...
iraqRnflvqteEqYiflhdalleaias
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 136-351 | 3.5e-59 | 195.0 | In-house | 32-245 (250) | alignment | ||
Range on Protein: 136-351
Range on HMM: 32-245/250.0
EGTTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTkCDKYWPDKDEERYGNFIVKFDNNITIPDILIrREFTLE
.| ||||||||.. ..| ||||| .||.|||.|..|..|. ||||| .|. || . .||| . |.||. |. .. . |. . |.. |
kgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyGdvtvsllskeefadytk.rklkls
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRS---GPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERP
. | .. | . ......||| | | .| |.... | ... .|..|.||||.||||.|.||.... . |. ... |.. .|..||
kakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerl.......kkekvvdvfkvikvlrkdrp
GMVQTRDQYRFCYLAISEAMNTV
..|....|| |.| .| .|...|
havesleqyvfvyeiilkaldsv
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 140-348 | 1.1e-58 | 193.4 | In-house | 64-275 (280) | alignment | ||
Range on Protein: 140-348
Range on HMM: 64-275/280.0
LSDYINASFIN---NG-----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE-ERYGNFIVKFDNNiTIPDILIRREFTL
.|||||...| .. || ||||| .| |||.|.|||.|..||||| |. ..|| .|||.... .||.| || .. . ||..|
etdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleygefsvkceke.detksyvlrelvl
ENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK--RSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydEKKQapSINLPKLVVEMRNERP
.. . .. ||| ..||. ||||| | ... ||.||. | . . .. |.||||||||||.| .... .|. |... ... ...| .||. |
kdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalali.....eaae..pvypldivrtmrdqra
GMVQTRDQYRFCYLAISEAM
.||| .||.| || ..
mlvqtasqykfvCeailkvy
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 136-348 | 1.4e-58 | 193.2 | In-house | 66-277 (314) | alignment | ||
Range on Protein: 136-348
Range on HMM: 66-277/314.0
EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEErYGNFIVKFDNNITIPDIlIRREFTLE
.| . ||||||..|. .| ||||| .|. |||......|. ||||| |... || ||||.. | ||.. |.. . . .. . | |..|
dgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellael.vvrifrve
N--LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH--EKRSGPIVVHCSAGIGRSGTFVAIHSIVaKFAkhydekKQAPSINLPKLVVEMRNER
. . ...|.. .||...||||..||| ||.||.| |.. |.. |.|||||||| ||.|||.||.... . .. ... . | ..|...
klargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl.dmi......eregvvdvfnavktlrsrk
PGMVQTRDQYRFCYLAISEAM
. ||.| .||.|.| .| ||
vnmveteeqykfiydvileac
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 140-354 | 2.9e-57 | 188.7 | In-house | 66-286 (288) | alignment | ||
Range on Protein: 140-354
Range on HMM: 66-286/288.0
LSDYINASFINNG-----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE--ERYGNFIVKFDNNITIpDILIRREFTLEN
|||||||... ..|.||.|| .|. |||.|..|| |..||||. .|| .|.|.|.||| . . ...|.. | .. . . ..|...||
kDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvret.ethvervlklet
LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH------EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKkqapsiNLPKLVVEMRNE
|. ...... | |.|.||..| | | .|.|. |.. .| |.|||||||.||.|.| . ..|... |. .....| .|..
ldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgngll......diiqvvsrlreq
RPGMVQTRDQYRFCYLAISEAMNTVLKK
| |||...|..|.| |. || . ||.|
Rrfmvqekeqlkfsyeavleaarrvldk
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 136-346 | 2.1e-56 | 186.1 | In-house | 65-288 (297) | alignment | ||
Range on Protein: 136-346
Range on HMM: 65-288/297.0
EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPD--KDEERYGNFIVKFDNNITIPDiLIRREFT
.... ||||||.|.. . ..| ||||| .|. |||.|.|||. .||| || .|. . || .|||. .. ...|.. |. . . | | ..
dedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeed.ykvrvle
LENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE---------------KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSI
..| |....||. |||...|||.|.| |.. .|.... | .. . ||||||||||||.|||... .... .. .
iknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrl.......eevgtv
NLPKLVVEMRNERPGMVQTRDQYRFCYLAISE
.. . | .|. | ..|| .|| |||||. |
dvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 141-350 | 8.6e-54 | 177.4 | In-house | 76-285 (290) | alignment | ||
Range on Protein: 141-350
Range on HMM: 76-285/290.0
SDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPdILIRREFTLENLKD-
.||||..|. . || ||||. ||.|||||.||.... |||||| . |. |.|| .||||.| ..||.| .| |. |. |.|.. ..| .
neyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetln.eyierklevknknsa
NKTRKIYHFQYTTWPDHG-TPVSTTGFLKFVSFVDHEKRS--GPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPGMVQ
...... ..| |.|...| . .| | . .. .... ..||||||...|||..|.|.. . | |. |.. ... ..| .||.||
gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkc.......ktegvidvfqvlksqRiqkpgsvq
TRDQYRFCYLAISEAMNT
| .||.. . . .....
tvqqyqgifqivltylds
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 138-353 | 1.1e-53 | 176.9 | In-house | 81-297 (297) | alignment | ||
Range on Protein: 138-353
Range on HMM: 81-297/297.0
TTLSDYINASFIN-----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFD-NNITIPDILIrREFTLE
.. |||||||.| . .|| ||||| .|. |||.|.||| . .||.||| ||. ..|..||||. .| |. . |.. . | | |. | | |
aeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylv.rsfylk
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH--EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEkkqapsINLPKLVVEMRNERPG
||. ..|| . | . .||..|.| |. .|.| |. || |||||||.| ||.|....| ......| | |.. . .|..|||
nlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvke......idiaatlehlrdqrpg
MVQTRDQYRFCYLAISEAMNTVLK
.|.|.||..|.. |..| .|..||
lvktkdqfefaltavaeevnailk
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 141-349 | 1.5e-52 | 173.6 | In-house | 79-285 (297) | alignment | ||
Range on Protein: 141-349
Range on HMM: 79-285/297.0
SDYINASFINNG--TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKtKCDKYWPDKDEERYGNFIVKFDnNITIPDILIRREFTLENLKDNKT
|||.||||.. .|.|| | .|. |||.|..... ..||||. ..|. | || .||.|| .|. |. .. |.||..... | ..
sDyvnasfvkgnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvll.svsereGfikrelevtkgkakar
RKIYHFQYTTWPDHGTPV--STTGFLKFVSFVD--HEKRS-GPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPGMVQT
| . .|.. |||. . |.. .||..| | ..... ||..|||.||.|| | ...| |.||. |. .... .|| .|.||| .|||
rvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaea.......krekevdifglvkklrqerpylvqt
RDQYRFCYLAISEAMN
..||.| | |. ||.
keqykfvyvavleall
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 137-346 | 6.5e-52 | 171.8 | In-house | 85-289 (319) | alignment | ||
Range on Protein: 137-346
Range on HMM: 85-289/319.0
GTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTreeenfKTKCDKYWPDKDEERYGNFIVKFDNNITIPDiLIRREFTLEN
| ||||||||.. . || .|||| ||. |||.||||.|. ||.|| | || .||| | ......| || | . . |.. | .
GeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveetae.yvvrdielse
-LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH----EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhyDEKKQapsINLPKLVVEMRNER
| . ||| | . |||.| | ... ....| | | |. .||||||||.||.|...... .. .. .|.|| ... ..| ..|..|
dgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrm....keekq...vdvynfvrdlrqqr
PGMVQTRDQYRFCYLAISE
. .|| || |.| |. |
ntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 141-348 | 8.2e-52 | 170.9 | In-house | 71-276 (515) | alignment | ||
Range on Protein: 141-348
Range on HMM: 71-276/515.0
SDYINASFI----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPD--KDEERYGNFIVKFDNNITIPDILIRrefTLENLK
|||.|||.| |. .||..|||. .. |||......| |.|.|. .|. | || ||||| | ..|.. |. . . ..| .|. ||
sdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikr...kltvlk
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV--DHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPGMVQ
....| . |..| |||.|.| |. .||.. | ||.. . |...|||||.|| | ...|.|.||. |.. .... ..| .|..|| .||
gddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvaha.......kttrmvdvfnfvtnirqkrpylvq
TRDQYRFCYLAISEAM
|..|| | | |. | .
tqeqyafiygavledl
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 137-346 | 2e-51 | 170.2 | In-house | 49-253 (284) | alignment | ||
Range on Protein: 137-346
Range on HMM: 49-253/284.0
GTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTreeenfKTKCDKYWPDKDEERYGNFIVKFDNNITIPDiLIRREFTLEN
| |||||||||. . || ||||| ||. |||.||||.|. ||.|| | || .||| | ......| || | . . |.. | .
GeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveesee.yvvrdielse
-LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH----EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhyDEKKQapsINLPKLVVEMRNER
| .. ||| | . |||.| | ... ....| | | |. .||||||||.||.|...... .. .. .|.|| ... ..| ..|..|
dgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrm....keekq...vdvynfvrdlrqqr
PGMVQTRDQYRFCYLAISE
. .|| || |.| |. |
ntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 141-349 | 4.7e-50 | 165.2 | In-house | 72-278 (315) | alignment | ||
Range on Protein: 141-349
Range on HMM: 72-278/315.0
SDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPD--KDEERYGNFIVKFDNNITIPDILIRREfTLenLK
|||||||.|. . .||..|||| .. |||.|..... |||.| .|. | || .|||| | ..|.. |. . . | .|. .. |
sdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vt..rk
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV--DHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPGMVQ
...|.. ||.| |||.|.. |. .||.. | |..|. ...||||||.||.| ...|...||. |.. |... ..| ..|..|| .||
seesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqi.......krtrsvdvfnfvknlrakrpylvq
TRDQYRFCYLAISEAMN
|...| | | |. | .
teeeyafiydavledll
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 140-352 | 2.1e-49 | 163.9 | In-house | 3-229 (272) | alignment | ||
Range on Protein: 140-352
Range on HMM: 3-229/272.0
LSDYINASFIN-------NGTYICTQGPLLNTIVDFWKMiWEQNSNIIVMLTREEENFKTKCDKYWP------------DKDEERYGNFIVKFDNNITIP
||.||||.... |......||| .|. |||.. .|.. . ||.|..||| . |||.||| . . .||.. |.. .. .
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTtgFLKFVSFVDHekrSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhydekkqapsI------
|...|. |. ...|...|..|| |||||.| .. .|...... . .||..||||||..|.||.||. ... .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld...ggpvlvHCsaGkdRTGtvvallllllg.............vsletiv
--------NLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMNTVL
| . | |.| |||.||| .||.|.| |. |.....|
ddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsll
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 141-350 | 2.1e-49 | 163.1 | In-house | 71-280 (287) | alignment | ||
Range on Protein: 141-350
Range on HMM: 71-280/287.0
SDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNItIPDILIRREFTLENLK-D
|||||.||. .| ...|. ||...|||.|...| ..||||..|.|| . .| .|||... .|.. ... |. . . | |.. ..| . .
pdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellnee.vnagyierklevknknka
NKTRKIYHFQYTTWPDHG-TPVSTTGFLKFVSFVDHEKRS--GPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPGMVQ
...... .|.|.|...| . | .| . . .... ..||||||...|||..|.|. . | |. |.. ... ..| .||.||
gdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkc.......kteGviDvfqvlksqriqkpgsvq
TRDQYRFCYLAISEAMNT
| .||.| . .. | ...
tveqykfindivleylds
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 127-345 | 8.8e-49 | 160.9 | In-house | 57-263 (283) | alignment | ||
Range on Protein: 127-345
Range on HMM: 57-263/283.0
EedhggsgdegttlsDYINASFIN-------NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITI
. |||||.|| . || .|.|| .|.||||||..... |||||. |. . || .||| . | ||.| | .. |
r..............dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrketts
pDILIRREFTLENL-KDNKTRKIYHFQYTTWPDHGTPVSTTGFLKF--VSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVakfakhyDEKKQAPSINL
. .|..|..| . ..| . |.|. | . | ..|| | |.. ||||||||.||||...|.|. . | .. . ...
.nsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasv.......kdaltesvvdv
PKLVVEMRNERPGMVQTRDQYRFCYLAIS
.. | ||..|...|||.|||.. . ..
favvkimreqrmmavqtldqyklvhelvl
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 139-348 | 1.1e-48 | 160.8 | In-house | 75-279 (315) | alignment | ||
Range on Protein: 139-348
Range on HMM: 75-279/315.0
TLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKdEERYGNFIVKFDNNITIPDILIRrefTLENLK
|||.||.||. ||..|||. ... |||....|.. ||||| |. | |..|||||| . ||.. | .. .. .| ||
phsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvr...tlsvvf
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV--DHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydEKkqapSINLPKLVVEMRNERPGMVQ
... |... ..||.||| | | .|. ..... | |.. |.||||||||.||.|||... ... . |. |.. ... .|. | .|||
gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaea...en....aidvynfitgvrqnrikmvq
TRDQYRFCYLAISEAM
. .||.| | |. |..
vaeqyqfiydalletf
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 138-353 | 1.2e-48 | 160.5 | In-house | 45-269 (270) | alignment | ||
Range on Protein: 138-353
Range on HMM: 45-269/270.0
TTLSDYINASFIN-----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGN-FIVKFDNNITIPDILIRREFT
. . |||| ... . .||...||| .|. .||.||||.... |||.| ||. ..||..||| . .| .. . .| . . . . |... .
dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlr
LEnlKDNKTRKIYHFQYTTWPDHGTPVSTT------GFLKFVSFV----DHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhyDEKKqapSINLPKL
|| .. ..|.. ||.|.|||||| | .. || . | .. ....|..||||||.||.||..|. .| .|.| .... ..
le..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlL....eetk...kvdvlai
VVEMRNERPGMVQTRDQYRFCYLAISEAMNTVLK
. |.|..|. .||. .||.| | |..| .....|
ieelRkdRmalvqhpeqyeflykavveyaerrak
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 140-347 | 7.3e-48 | 158.1 | In-house | 75-295 (300) | alignment | ||
Range on Protein: 140-347
Range on HMM: 75-295/300.0
LSDYINASFINN------GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK----DEERYGNFIVKFDNNiTIPDILIRREFT
..||||| |. .|| .|||| .|. |||.|.|||. ..|||||.|||. |.|. ||.|.. .. ..|.| | . . | .| . ..
stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfs.edsdsvittglk
LENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVD----H-------EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhYDEKKQapsINLPK
|. | .. |...|.||| ||||| | .|||... |. . .... |..||||||.||.| . ..| .. .. |...|
lkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliat....lehnee...idikk
LVVEMRNERPGMVQTRDQYRFCYLAISEA
. .|. | .||| ||.| | .. .
vlarLreqrmllvqtlaqYkfvYkvliky
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 56-348 | 7.6e-48 | 157.8 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 56-348
Range on HMM: 1-171/182.0
NKLKNRYSNVLPFEETRvkiniddddddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegttLSDYINASFIN----N
|. |||||..||.. .| .|||||... .
nldknrysdilpydhsr...................................................................dldyInanlylgslpa
GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTreeenfktkCDKYWPdkdeerygnfivkfdnnitipdilirreftlenlkDNKTRKIYHFQYTTWPD
..|.||||||.|. ||..|..|.. ..||.|| .. ||| .. .| .....|. |||
trfiatqgpllstvadflrmlkelgittivnlt.........eelywp...................................ellerlgiqylylpwpD
HGTPVsTTGFLKFVSFVDHekRSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhydekkqapSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAM
||.| . .|.|. | . ..||..||||||.||.||.||. . . ...|.. | ..|. |||||.| .||.|..||. | .
hgvpd.ldelldfieevle..eggpvlVHCsaGvgRtgtlvaaylmkkl............gvsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 139-350 | 3.3e-47 | 156.2 | In-house | 74-293 (325) | alignment | ||
Range on Protein: 139-350
Range on HMM: 74-293/325.0
TLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTrEEENFKTKCDKYWPDK--DEERYGNFIVKFDNNITIPDIlIRREFTLEN
. |||||||.... ... .| || .|| |.|... . .. ..|.| | .. | .| .|||.. . ..| . ||. .| | . | . . .
pssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvln.eldlgkdrcavywpkemgksktfGglevklrtieeisdy.vhrvldvkq
LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH--------EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekkqaPSINLPKLVVEMR
|. .|| . ||. .|.| |.. . .. .. |.. | |.||.||||||.||.|.|....|..|| .. .... . | .|
vkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakviee.......srvdifgfvkklr
NERPGMVQTRDQYRFCYLAISEAM---NT
..|| ||.| ||| ..| |. ||. ||
kdrpsmvetvdqyiliyealveaymsgnt
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 136-347 | 1.7e-45 | 150.0 | In-house | 60-276 (287) | alignment | ||
Range on Protein: 136-347
Range on HMM: 60-276/287.0
EGTTLSDYINASFI----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE-RY-GNFIVKFDNNITIPDiLIRREFT
|| |||||| .. .. ..|..|||. |. |||....|..| ....||| |. . || ||||... | | .| .| .| |. | .
egelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePe.ygvralr
LENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV-D------HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVE
| .|. ...| . ... .|||.. . .. |...|| | . . ||.|||...||||||...|. .| . .. .. . |.
lidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrl.......edlGrvdvaavvir
MRNERPGMVQTRDQYRFCYLAISEA
.|. | ..||. |.|. | |.
lreyraalvqavvqlrllyealvty
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 140-344 | 2.3e-45 | 149.8 | In-house | 11-169 (176) | alignment | ||
Range on Protein: 140-344
Range on HMM: 11-169/176.0
LSDYINASFINNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDkdEERYGNfivkfdnnitipdilirreftlenlkdnktr
.|||||..| . .|.||||| .|. ||..|..|.. ...|.|| | | . ||. |||. .|..|
dldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi...............................
kiyHFQYTTWPDHGTPVStTGFLKFVSFVDHEKRSG-PIVVHCSAGIGRSGTFVAIHSIVAkfakhydekkqAPSINLPKLVVEMRNERP-GMVQTRDQY
..... |||||.| . . .|... |.. ..| |..|||||||||.||.||. . ... . . ..|. || |.|||..||
...qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllel...........ekglsveealalvreqRplgavqtpeQy
RFCYLAI
||.| ..
rflyefe
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 140-341 | 3.8e-45 | 149.0 | In-house | 4-154 (172) | alignment | ||
Range on Protein: 140-341
Range on HMM: 4-154/172.0
LSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREeenfktkcdkywpdkdeerygnfivkfdnnitipdilirreftlENLKD
|||||||... .|.||||| ||. |||.|..|.. ..||.||.. .....
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lydpe
NKTRKIYHFQYTTWPDHGTPvSTTGFLKFVSFVDH---EKRSGPIVVHCSAGIGRSGTFVAIHSIVakfakH-YdekkqapsiNLPKLVVEMRNERPGMV
. .| .....|. |||||.| .. .|.|..|.|. ....||..||||||.||.||.||.. . . . .| . | ..|. |||.|
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl.........sleeavalvrekRpgav
QTRDQYRFCY
|. .||||.|
qnpsqyrfly
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 136-344 | 9.9e-45 | 147.6 | In-house | 28-235 (237) | alignment | ||
Range on Protein: 136-344
Range on HMM: 28-235/237.0
EgttlSDYINASFINN-----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE-ERYGNFIVKFDNNITIPDILIRREFT
. ||||||..... .||..|||| .. |||.|.|... .||||| |. . || ||||. |. . || . | . . . | .| .
g....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeefsdytvrslll
LENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSF----VDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKfAKhydEKKQapsINLPKLVVEMRN
..|. .. | |. .|.|.|||.| | |. .|.| | .||| ..|||||.||.| |. | ... . || ||| ... . | . .
skrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrq.ak...ekkv...vdiynyvysiee
ERPGMVQTRDQYRFCYLAI
.|| ..||.||| | . .|
drpyiiqtkdqyvfihqti
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 136-348 | 1.7e-43 | 143.3 | In-house | 65-290 (296) | alignment | ||
Range on Protein: 136-348
Range on HMM: 65-290/296.0
EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKtKCDKYWPDKDEERYGNFIVKFDNNITIPDILIRrEFTLE
.| ||||||.... . || |..| .|. .||......... .|.||.. . | .. .||| | .|.||...|. .. . ... || .| |
dGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqygeifveiveekqyanlkir.tfklt
NL----------KDNKTRKIYHFQYTTWPD-HGTPVSTTGFLKFVSFVDH-------EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPS
. .|| . .||.|.|. . |.||....... | .. ||.||..| | .||| ..|| . . ..
kkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelv.......ekeee
INLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAM
... . | .|..||..|.. ..|...| ..||.
vdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 141-341 | 5.9e-43 | 141.9 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 141-341
Range on HMM: 2-163/174.0
SDYINASFINN----GTYICTQGPLLntivdFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDkdeerygnfivkfdnnitipdilirreftlenLKDN
|||||||... . .|..|||| ||.|..|......|||..|.|. ..|| |||. |..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lred
KTRKIYHFQYTTWPDHGTPVSTTgFLKFVSFVDHE---KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKkqapsinlPKLVVEMRNERPGMVQT
.| .....|. |||||.| ... .|.||.||.. ...||..||||||.||.||.||. . ... .|| |.|. |||||||
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvda........ldlvrelRlqrpgmvqt
RDQYRFCY
.||||.|
psQyrfly
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 151-341 | 2.5e-42 | 139.5 | In-house | 8-143 (152) | alignment | ||
Range on Protein: 151-341
Range on HMM: 8-143/152.0
NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWpdkdeerygnfivkfdnnitipdilirreftlenlkdnktrkiyHFQYTTWP
. .|.||||. ||. |||.|..|.. ..|||||...|. | ||..|. ..... ||
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................qylhlpwp
DHGTPVSTTGFLKFVSFVDH--EKRSGPIVVHCSAGIGRSGTFVAIHSIVakfakhydekkqaPSINLPKLVVEMRNERPGMVQTRDQYRFCY
|||.| .. .| .. |... ....||..||||||.||.||.||. . ..| . | .|. |||.|.. .|.||.|
DhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.............lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 137-348 | 3.3e-41 | 136.2 | In-house | 72-279 (439) | alignment | ||
Range on Protein: 137-348
Range on HMM: 72-279/439.0
GTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKtkcdkYWPDKDEERYGNFIVKFDNNITIPDILIRrEFTLEN
| | |||| .|. . || |||| .| |||....|... ||||| | .| ||| ..| ||. .|. | || .|. || | . |
gvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvir.gfkvfn
LKD--NKTRKIYHFQYTTWPDHGTPVSTTGFLKF---VSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNER
.| .| | . .|.|..|||. | .. |.| . . .. ||.|||||||.||.|| .|. . .. | ... .| .|..|
erdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeql.......klenkvdikgivkvlrkqr
PGMVQTRDQYRFCYLAISEAM
|||. || | | |. | .
kqmvqalcqyvfiynavledi
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 140-347 | 1.2e-40 | 134.1 | In-house | 34-239 (239) | alignment | ||
Range on Protein: 140-347
Range on HMM: 34-239/239.0
LSDYINASFINN-----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDeERYGNFIVKFDNNITIPDILIRrEFTLENLK
|||||||.. . .||.||| . . |||.|.|.. .||||| | .| || .|||| .| |. | . . . | .|| | . ..
hsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst.skycnlrvtlrktevfadyiir.tfvmsqvg
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRS--GPIVVHCSAGIGRSGTFVAIHSIVAKfAkhydeKKQApSINLPKLVVEMRNERPGMVQ
. . | .|....| |||.| | .| | . . .. | |.|||||.||.|.|. | ... . | ||| .... . | .|..|| |||
qteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq.a.....kkqk.tvdifnyvkairedrphmvq
TRDQYRFCYLAISEA
| .|| | .||. ||
tseqyvfihlavlea
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 141-338 | 2.5e-40 | 133.0 | In-house | 81-273 (290) | alignment | ||
Range on Protein: 141-338
Range on HMM: 81-273/290.0
SDYINASFIN--NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDNNITIPDILIRREFTLENLKDN
||. | ... . ..| |||.| .|..|.|.|. ... |||| |. |.||..|.|.|. | .|.. | .. . . .|.. ... . ..
GdyvhanyvkGlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsG
KTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVdhEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAkhyDEKKqapsINLPKLVVEMRNERPGMVQTRDQ
| |..|.. .|||. . || .|. . . | |||.||||||||||.|||||| . . | |. ..| .|| .|| | . || |
kehklkhlkikswpdksvalstlallrtlril..rkasGpvvvhcsaGiGrtGtfvaievglqill...dGke....ldlldlvralrnsrlnsvqvdiq
YR
|
yl
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 41-353 | 3.5e-40 | 134.0 | In-house | 31-285 (314) | alignment | ||
Range on Protein: 41-353
Range on HMM: 31-285/314.0
RALETDKFRSALEAKNKLKNRYSNVLPFEeTRVKINIDDDdddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdEGttl
..| . | .|. |||| ..||.. .||... . .|
svlpeltilvadlflnrdknryldilpad.nrvilpglpv.......................................................sg...
SDYINASFINN-GTYICTQGPLLNTIVDF----------WKMI--WEQNSNIIVM---------------------LTREEENFktkcdKYWPDKDEERY
|||||||.... ..|.||||| .|.||| |.|. ...|. .||| |.. .|. ... .| | .
sdyinasyvdgflkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.....neptaadlell
GnfivkfdnnitipdilirrefTLENLKDNKTRKIYHFQYTTWPDHGTPvSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakHyd
. . .. .| .... .. .||...| .. |..|. |.. .. ||..|||.||.||.||||.. .. .. .
k.....................eelydpelferlgikylripvpDgsap.lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll..g..
ekkqapsINLPKLVVEMRNERP-----GMVQTRDQYRFCYLAISEAMNTVLK
..| . . ..|. || |.... .|| |.. |. |......|
.......vsleealedvrlkRpinpnpgfieqleqyefilealleylkflkk
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 140-345 | 3.6e-40 | 132.6 | In-house | 35-238 (239) | alignment | ||
Range on Protein: 140-345
Range on HMM: 35-238/239.0
LSDYINASFINN-----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDeERYGNFIVKFDNNITIPDILIRrEFTLENLK
|||||||.. . .||.||| . . |||.|.|.. .||||| | .| || .|||| .| |. | . . . | .|| | . ..
hsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst.skycnlrvtlrktevfadyiir.tfvmsqvg
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRS--GPIVVHCSAGIGRSGTFVAIHSIVAKfAkhydeKKQApSINLPKLVVEMRNERPGMVQ
. . | .|....| |||.| | .| | . . .. | |.|||||.||.|.|. | ... . | ||| .... . | .|..|| |||
qteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq.a.....kkqk.tvdifnyvkairedrphmvq
TRDQYRFCYLAIS
| .|| | .||.
tseqyvfihlavl
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 137-345 | 1.2e-39 | 131.1 | In-house | 14-168 (178) | alignment | ||
Range on Protein: 137-345
Range on HMM: 14-168/178.0
GTTLSDYINASFINNGTYICTQGPllntiVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEerygnfivkfdnnitipdilirreftlenlkdn
|. |||||||.| .| |.....| .|......|.. . ||.|| | |... |||.|||.. .
glersdyinaseilpglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................................
ktrkiYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE--KRSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhydekkqapSINLPKLVVEMRNERPgMVQTR
...... .||||.| .. ||.|| |... .. ||..||||||.|||||.||. . ...|.. . ..|. || .|...
.....iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl............glsleeaielvrerRp.ivpnp
DQYRFCYLAIS
.|.|..|. .
gqlrqLyefel
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 141-349 | 1.7e-39 | 130.3 | In-house | 70-294 (301) | alignment | ||
Range on Protein: 141-349
Range on HMM: 70-294/301.0
SDYINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPD--KDEERYGNFIVKFDNNITIPDILIRREF------
.|||||.|.. .| .|||. .|.||||..||.. |||.| ..|. |.|| .|||. ...|..|.| |.. |. ..|| .||.
reyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdg
--------TLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR---SGPIVVHCSAGIGRSGTFVAIhSIVAKFAkhydekKQAPSINLP
... .|...... .| | ||..| |. . | | .. ||.|||||....|||..... || . | ...
snngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsv.siglEQc......kaegVVdvf
KLVVEMRNERPGMVQTRDQYRFCYLAISEAMN
... .| .||.|.| .|| . | .|.. ..
qvtkavrrskpgaVtTLeqytsiydvidmylq
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 140-341 | 2.1e-38 | 127.1 | In-house | 66-270 (307) | alignment | ||
Range on Protein: 140-341
Range on HMM: 66-270/307.0
LSDYINASFI----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERygNFIVKFDNNITIPDI---------LIRR
|||| | .. . .||.|||| ||. .|| |. ... . ..|| . | | ||..||| .. .. . .. | |.. .. .
asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqk..lvfgeapntisvanlgakklapdedlin
EFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKrsGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKkqapsiNLPKLVVEMRNE
||. .|.| | |.|.. |||.|.| . . ... | .. |.|||||||.||||| ||| . | . . | .. ||| |.|..
vttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydt..npvvvhcsaGvGrsGtivaislvqdkmiaGinck......dmkklveelrsq
RPGMVQTRDQYRFCY
|. .|| || . .
rhyaiqteaqylylh
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 140-344 | 7.8e-38 | 124.8 | In-house | 2-149 (151) | alignment | ||
Range on Protein: 140-344
Range on HMM: 2-149/151.0
LSDYINASFINNGtYICTQGPlLNtivDFWKMIWEQNSNIIVMLTREEENFktKCDKYWPDKDeerygnfivkfdnnitipdilirreftlenlkdnktR
||||||.|.. .| .....|| |. ||.....|.. . ||.|. |||. .| .|.|. . .
lsdyinfsyvtgg.lyrsggp.la...dflellkelgiktivnlrseeerg..ycpeylpelg....................................i
KIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHeKRSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhydekkqapsINLPKLVVEMRNERPGMVQTRDQYRF
...|.... |||.|.|.|. .|.|...... |..||..||||||.||.||.||. . . ..| . . |.| |||.||. .|..|
evlhipildwpdpglplsfdavleflellld.kkngpvlvHCsaGkgRTGtlvalylmllg.............vsleealeeyrlkrpgvvqpnqqflf
CYLAI
...|.
qlfal
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 140-347 | 2.2e-37 | 123.4 | In-house | 72-235 (392) | alignment | ||
Range on Protein: 140-347
Range on HMM: 72-235/392.0
LSDYINASFI----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFktkcdkywpdkdeerygnfivkfdnnitipdilirreftlenlKD
|||.|||.| |. .||..||| .. |||.|....| |.|.|. .| |
dsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...........................................kg
NKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV--DHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKfAkhydekKQAPSINLPKLVVEMRNERPGMVQT
...| . |..| |||.. | |. .|||. | |. . . |...|||||.||.| ..| |.||. | |.. ... ..|...|..|| ||||
ddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvah.a......kktrmvdvfnfvtnirrkrpymvqt
RDQYRFCYLAISEA
..|| | | |. |
keqyafiygavled
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 141-311 | 6.6e-37 | 122.2 | In-house | 75-265 (418) | alignment | ||
Range on Protein: 141-311
Range on HMM: 75-265/418.0
SDYINASFINNG---TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK-----------DEERYGNFIVKFDNNITIPDI-LIR
|||||| .|. .||||||| ||| |||.|.||. |||||.|| || . |||.|||.. .| .| . |.. . | |. .|
sdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiit
REFTLEnlKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSF--------VDHEKRSGPIVVHCSAGIGRSGTFVAIHsIVAKFAKHYDEKKQA
|. | . .|| | ..|| |||| | | | ... . | ||.||||||.||.|||.. |. | || .. .|
rnirlt..fegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctav.immkkldhyfkqlda
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 141-358 | 3.6e-35 | 116.1 | In-house | 85-296 (305) | alignment | ||
Range on Protein: 141-358
Range on HMM: 85-296/305.0
SDYINASFINNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPD---ILIRREFTLENLK--D
..|. . .| . .||.|||| .|| .|| |. ... . |||| . | | || .||| |. .|.. . || ||
anyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysg
NKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKrsGPIVVHCSAGIGRSGTFVAIHSIVAKFAkhydEKKQAPSinLPKLVVEMRNERPGMVQTRD
... . |.|.| ||| | | |...| . | ||||||||||||.|| ||| |. | | |.|..| .|.|| .|..| .|.
dqkmsvrhlqwtewpdrgvppckltslellsairgsk..vpivvhcsagigrtgtivaieyilekia....enkpcpp..mpelvkalrdqrafsiqndv
QYRFCYLAIseaMNTVLKKEQKK
|| | . . .| .|.| ..|
qylfihrvm...lnyflekykek
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 150-339 | 1.4e-34 | 114.3 | In-house | 88-272 (301) | alignment | ||
Range on Protein: 150-339
Range on HMM: 88-272/301.0
NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEER--YGNFIVKFDNN-ITIPDILIRREFTLEN-LKDNKTRKIYHFQ
. .|.||||| || ||| |. . . ||||... |. ..||..| | | .|. | | .| |. . . ...|.. .|. .. .|| . |.|
hphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyq
YTTWPDHGTPVSTTGFLKFVSFVDHEKRsgPIVVHCSAGIGRSGTFVAIHSIVAkfakhydEKKQAPSINLPKLVVEMRNERPGMVQTRDQYRF
|..|.|.|.| | . ... .| . .. ||||||||||||| .|.. . . | . | |.| . . ..|..| |||. | .
ysewtdrgvPkshaelfdlmelvkksek..PivvhcsaGiGrsvafigteylar.......eveadptieltealkhlrehrwngvqtnsqlyw
|
|||||||||
| PTPc_DSPc_SM00012 | 241-345 | 2e-32 | 106.9 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 241-345
Range on HMM: 2-104/105.0
IYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR----SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkqaPSINLPKLVVEMRNERPGMVQTRDQ
..|..||.|||||.| ... .|... |...|. |.|.|||||||.||.|||||. .. .. |. .... ..| |.|..||||||| .|
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket......kevdifqivkelrkqRpgmvqteeq
YRFCYLAIS
| |.| |.
ylflyrall
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 141-340 | 9.3e-31 | 101.5 | In-house | 71-261 (281) | alignment | ||
Range on Protein: 141-340
Range on HMM: 71-261/281.0
SDYINASFINNGtYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE--ERYGNFIVKFDNNiTIPDILIRREFTLEnlKDNKT
..|| . |.. | || |||| .| |||.|||..|. |||| . | . || .|.| . .. .. |.... |. |. . | . .|
anyirspflkrg.yiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyeds.tvnkslvttrlnls..yeget
RKIYHFQYTTWPDHGTPVSTTGFLKFVSFVdhEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDekkqAPSINlpKLVVEMR-NERPGMVQTRDQY
| | |. . ||| | |. .|| . . || | |.|||||.|||||..|. . |. | |. ..| .| | ||| .||
rlithwlwkewpdwqvpessevmlkilrki..rarstppvihcsagvgrsgtlmaveialqsihshft....lpdik..qivshlrvtgraasvqtlqqy
RFC
.
mli
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 138-355 | 1.5e-28 | 94.6 | In-house | 54-266 (267) | alignment | ||
Range on Protein: 138-355
Range on HMM: 54-266/267.0
TTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTReeeNFKTKCDKYWPDK--DEERYGNFIVKFDNNITIPDILIrreFTLE
|. .|||||... . ..| ||.|| ||| ||...| .|. .||.||. |. . ..|| | . ..| .. |.. . | | |||
tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltk...vftdnirlfwPPkmgqakkyqdltvehslekeendyqi...itle
-NLKDNKTRKIYHFQYTTWPDHG--TPVStTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhydeKKQAPSINLPKLVVEMRNERP
..|.. .... . | | | .. .. . |. . |.||.||.|.||||||. |.| . . |. .. ... ..|. |.
lkfknesahnvtlyyykkwnintnnkpyl.kplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqler.......aktegvsdifdflrkirsqri
GMVQTRDQYRFCYLAISEAMNTVLKKE
|.|.|...| ... ..| . ||.|
glvdtkeryiyihellaeyaegrlkee
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 141-344 | 2e-28 | 94.1 | In-house | 73-283 (305) | alignment | ||
Range on Protein: 141-344
Range on HMM: 73-283/305.0
SDYINASFI----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE------ERYGNFIVKFDNNITIP-----D-ILI
.|| | .. | .|||| || .| ||| | .... . | || | || .|.. ||. |. .|||. |. . .
heyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvt
RREFTLENlKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSfvDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekKQAPsiNLPKLVVEMR
. ....| .|.||. |. . ||| | | . . |... . |||||||||||||.|. | . |. .. .. . |... .|
etvlvieg.pgekarkvthyhwidwpdrgvpaadlailelle..karpskgpivvhcsagigrtgsvvmleyildqllag....qiie..dtdkilqkir
NERPGMVQTRDQYRFCYLAI
..| .|| .|| | . |
eqrnnsiqtdaqylfvhqvi
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 220-345 | 6.5e-28 | 92.6 | In-house | 26-140 (145) | alignment | ||
Range on Protein: 220-345
Range on HMM: 26-140/145.0
PDILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK-RSGPIVVHCSAGIGRSGTFVAIHSIVAkfakhydekkqaPSINLPK
| |.. ..| . ... .|......|. |||||.| .. .|.|. |... . ||..||||||.||.||.||.. . ...|..
kdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll............lgvslee
LVVEMRNERPGMVQTRDQYRFCYLAIS
. ..|. |||.|.. .|.||.|...
alelvrsqrpgavpnpgqlrflyefel
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 83-264 | 7.4e-28 | 92.2 | In-house | 7-189 (297) | alignment | ||
Range on Protein: 83-264
Range on HMM: 7-189/297.0
DEDDNEDDIIVSNNNNNNNNNEKRikRNSIGSSGQSDVMSNssdeEDHGGSGDEGTTLSDYINASFIN------NGTYICTQGPLLNTIVDFWKMIWEQN
| ..| |... ... .. || .|. . |... .| . | .||||| .. . ||..|||| .|. |||....||.
keleaekdllldeargesfssakr..nsslrknryrdilat....ddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqd
SNIIVMLTREEENFKTKCDKYWPDKDEERY--GNFIVKFDNNITI--PDILIrREFTLENLkdNKTRKIYHFQYTTWPDHGTPVSTTGFLKF
..|||... .|. . || |||. ..|| |...|.| . . . . |..| ...|.. | |. .||||| | .|
vrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrvil.telqliyr..sesrvvrhvqflswpdhGvpsdledlvrf
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 164-348 | 5.8e-27 | 89.4 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 164-348
Range on HMM: 40-221/255.0
TIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDNniTIPDILIRREFTLENLK-DNKTRKIYHFQYTTWPDHGTPVSTTG
|. |...| .... .|||. .|. . ||..|.| . .| .. . | . .. |...| . .| ||... |..|. |... .| .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelare
FLKFVSFVdheKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKkQAPSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAM
|. . | . | ..|||||.||||| .|| . .. |. . |. .. .. .|. |.|..|.. ..| | |. | . . .
ilnilkvv...rdsksvvvhCstGiGrsaafvlaelvyqkmirsldtt.etveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 143-350 | 6.7e-27 | 89.0 | In-house | 69-278 (312) | alignment | ||
Range on Protein: 143-350
Range on HMM: 69-278/312.0
YINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPD-------KDEERYGNFIVKFDNNITIPDILIRREFTLE
|| | |.. ..|||||| ||.. ||.. | |..|. |. || || | .| | .. . . | . | . .
yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrvlkvv
NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRsgPIVVHCSAGIGRSGTFVAIHSIVAKFaKHydEKKQapsiNLPKLVVEMRNERPGMV
. |. |.|...||||| | | |...| | ..|. |.. |||||.||.||.. | |..| . .| .|| |. . | .|..| |
vkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk..pviahcsagvgrtgtlaliesmiaal.rh..prkq....nvkdsfvllrkdrarsv
QTRDQYRFCYLAISEAMNT
.. || .. .. | . .
rvfpqyvyalrcvleflys
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 142-347 | 1.4e-26 | 88.1 | In-house | 60-269 (285) | alignment | ||
Range on Protein: 142-347
Range on HMM: 60-269/285.0
DYINASFI-----NNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDN--NITIPDiLIRREFTLEN
||| ||.. .. ||| ||||| .|. |||.||.... ..|| | || |.|.| | ..|.. . . . . .| | .|. |
dyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiag.tilnaltvin
LKDNKTRKIY--HFQYTTWPDHGTPVSTTGFLKFVSFVDH-EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAkhydekkQAPSINLPKLVVEMRNERPG
.| . .| | | |||. .| . .... .| . . . ||.||||||.||. ||| | . . | |.. .| ||| |
tedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirim.......enpniemldivremramrfq
MVQTRDQYRFCYLAISEA
||.. |. | |. . |
avqshmqflflyvvlmey
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 153-341 | 1.7e-26 | 87.6 | In-house | 6-197 (199) | alignment | ||
Range on Protein: 153-341
Range on HMM: 6-197/199.0
TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD--EERYGNFIVKFDNNITIPDILIRREFTLEN-LKDNKTRKIYHFQYTTW
||.|| || .|. |||.|.|| | |||. .. | .. ||| . .||.. | | || | .| ||.| |.|.|.|
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
PDHGTPVST--TGFLK---FVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVakfaKHYDEKKqAPSINLPKLVVEMRNERPGMVQTRDQYRFCY
.. || . ||. || ... |..|||| | | .| |||. | . ..| | . ..| .. .|. | |.. . ..| | |
kekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigv....rsheesk.tsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 153-341 | 1.8e-26 | 87.6 | In-house | 5-196 (198) | alignment | ||
Range on Protein: 153-341
Range on HMM: 5-196/198.0
TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD--EERYGNFIVKFDNNITIPDILIRREFTLEN-LKDNKTRKIYHFQYTTW
||.|| || .|. |||.|.|| | |||. .. | .. ||| . .||.. | | || | .| ||.| |.|.|.|
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
PDHGTPVST--TGFLK---FVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVakfaKHYDEKKqAPSINLPKLVVEMRNERPGMVQTRDQYRFCY
.. || . ||. || ... |..|||| | | .| |||. | . ..| | . ..| .. .|. | |.. . ..| | |
kekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigv....rsheesk.tsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 161-356 | 4.5e-26 | 86.3 | In-house | 43-236 (263) | alignment | ||
Range on Protein: 161-356
Range on HMM: 43-236/263.0
LLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDNNITipDILIRREFTLENLK-DNKTRKIYHFQYTTWPDHGTPVS
|..|| |...| .... .|||. .|. . ||..|.| . .| .. | | . . |.|.. . |..|. ||... |..|. |... |
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpel
TTGFLKFVSFVdheKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKkQAPSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISE-AMNTVLKKEQ
. |. . . . | ..|||||.||||| |. . .. |. . |. .. .. .|. |.|..|.. ..| | | | . . .| | |
areilnilkva...rnskslvvhcstGiGrsaafsvaElvyqkmirsldtt.stveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakgel
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 143-358 | 5.3e-26 | 86.3 | In-house | 69-279 (288) | alignment | ||
Range on Protein: 143-358
Range on HMM: 69-279/288.0
YINASFINNGTY----ICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD--EERYGNFIVKFDNNITIPDILIRReFTLENLKDN
||.| . . | ||.| || || .|||. |.. . ||||.. | | | ..|.| | . |.| . .. . | |.. .| . |
yiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkv.sllriskeg
KTRK-IYHFQYTTWPDHGTPVSTTGFLKFVSFVdhEKRSGPIVVHCSAGIGRSGTFVAIhSIVAKFAKHYDEkkqapsINLPKLVVEMRNERPGMVQTRD
.... . . . |.|.| | . .|... . .. |||||.|||.||.||.. | |... .. | . ...|. ..|.|| .||
eekvivkilhlleWdddgvPenylsplrllevl..kslqkPivvhssaGvGrtgtlili.lialeslrlddf......lgirsllaklreerfkaiqtem
QYRFCYLAISEAMntVLKKEQKK
|| . . . | . .||| ...
qylyvhrcvleel..llkkykvl
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 229-342 | 1.4e-25 | 85.2 | In-house | 37-139 (144) | alignment | ||
Range on Protein: 229-342
Range on HMM: 37-139/144.0
TLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE-KRSGPIVVHCSAGIGRSGTFVAIHSIVakfakhydekkqAPSINLPKLVVEMRNER
| | .. .| ....... |||||.| ... .|.|. |... ...||..||||||.||.||.||.. .. ..| . . ..|. |
teeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk............klglsleealalvrsrr
PGMVQTRDQYRFCYL
||.|....|.||...
pgavpnpgqlrfLle
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 141-340 | 3.1e-24 | 80.1 | In-house | 79-282 (310) | alignment | ||
Range on Protein: 141-340
Range on HMM: 79-282/310.0
SD-----YINASFINNgTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVK-FD---NNITIPDILI---RRE
| |... .. . |.||.|||| ||.|||.||... .. |..| . |. . || ||| | || | . ... | .. . .
edyihanyvktnylrs.tficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdn
FTLENLK-DNKTRKIYHFQYTTWPDHGTPVSTTGFLKfvSFVDHEKRSGPIVVHCSAGIGRSGTFVaihsivaKFAKHYDEKKQAPSINLPKLVVEMRNE
... . | .. .. ||| | | . . . | || |||||||..| .. | . ..| .. ... ... |....
vpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp..qrllaqvrhgpcvvhcsagkdrlyvvv.......alklkidkldrglkvdaeevktellks
RPGMVQTRDQYRFC
| .|| || .
raiciqtelqylii
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 48-349 | 2.3e-22 | 74.0 | In-house | 32-271 (307) | alignment | ||
Range on Protein: 48-349
Range on HMM: 32-271/307.0
FRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegttlsDYINAS
.. |... |. | | | . .|||... . |.| |
lttaasdnnlekarskrvhckdssrvklelrrGqyld.........................................................dfihan
FINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENfkTKCDKYWPDKDEE--RY--GNFIVKFDNNITIPDILIRRE-FTLeNLKDNKT
.. . ..|..| || || |||.|..... . ||||| |. .|. ||| ... .. |.. .. . .| | | . | |..
rvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklkl.vGgddee
RKIYHFQYtTWPDHGTPVSTTGFLKfvsfvDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHyDEKKQapsiNLPKLVVEMRNERPGMVQTRDQYR
| . |.|. . . | |. . | |.||.. |. ...|.||| . .. . |. . . || .| .|. |.. .|
rflehwqg.dvnnssdvysplrvlr.....klrnlskpvvvqdilGvskaatlvaieiallsllrG.pitks....lvlravvflrlrrrlsvesvllyl
FCYLAISEAMN
| | . .
fvyrlvlfffr
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 160-348 | 4.8e-22 | 72.8 | In-house | 99-288 (302) | alignment | ||
Range on Protein: 160-348
Range on HMM: 99-288/302.0
PLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKF-DNNITIPDILIRREFTLENL-------KDNKTRKIYHFQYTTW
| .|. .| .| . | |.| |. |. . || .|. || .| ..|.. || . . . . ...|.| .. |... . . .....|
pkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsaw
PDHGTPVSTTGFLKFVSFVDHEKRSgpIVVHCSAGIGRSGTFVAIhsivaKFAKHYDEKKQApsINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAM
||||.| . |. . | . |.. ..||||||.||.||.||| |. . ||. .| ..|. .|. | | ||. .| . | .. ..
pdhGapkeaytaldilkfcesykkn..vlvhcsaGvGrtGtlvai.....kyGiqlcskkkv..tdllsivlpvrqcryGavqdeqqliylllcvtkgl
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 141-350 | 5.6e-21 | 69.9 | In-house | 46-265 (290) | alignment | ||
Range on Protein: 141-350
Range on HMM: 46-265/290.0
SDYINASFIN---NGTYICTQGPLLNT-------IVDFWKMIWEQNSNIIVMLTREEENFKT----KCDKYWPDKDEE--RYGNFIVKFDNNITIPDIlI
.||| |... . | || |. .. | .|| |. . ... .||| ||. . | || |.. .| ..... || . .. |. .
ddyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddv.e
RREFTLeNLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDheKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDekkqapSINLPKLVVEMR
.|| .. . |.. .. | .. | . .. .| .|. ...| .. |..||| || || .. || |.|. . |..| ... ..|
tRelvv.kfddeeeftvtHsllkgWnklnvqedtktllsliqkvk..asktpvivHcvdGiSrsAalaaiilgyQkiaetsg......svkledvlkalr
NERPGMVQTRDQYRFCYLAIS----EAMNT
..| .... .. | .| |....
kqralaitsalelafvdagivllaievldq
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 141-260 | 1.4e-19 | 64.9 | In-house | 56-182 (319) | alignment | ||
Range on Protein: 141-260
Range on HMM: 56-182/319.0
SDYINASFIN-----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD----EERYGNFIVKFDNNITiPDILIRREFTLE
. |..||.. . ||..| .| .. |||...|||.| .|| || |. .| .|.| |. .. ||.. | . .. . | . . |
deyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrev.kdryaistlllk
NLKDNKTRKIYHFQYtTWPDHGTPVSTTG
.......|.. |. | |.. . | . .
rvdkeesrelthywy.kwleaevPaeeaa
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 57-215 | 2.8e-19 | 64.0 | In-house | 48-164 (350) | alignment | ||
Range on Protein: 57-215
Range on HMM: 48-164/350.0
KLKNRYSNVLPFEETRVKINIDDDDDdeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhgGSGDEGTTLSDYINASFINNG----
||||.|.||.| .|||.. . . . .|||||....
faknrYknilPYehsrvkLkkslkss.................................................dakkhslstnDYinanYlkltrfsv
------TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDeerYGNFIVKFDN
|| ||.|| .|. ||.|.| . . ..|..|| . |. ||..||.. . | .. ||. .
einpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegs...ydditvklas
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 142-360 | 3.1e-19 | 63.5 | In-house | 76-297 (302) | alignment | ||
Range on Protein: 142-360
Range on HMM: 76-297/302.0
DYINASFINN----GTYICTQGPLLNTI---VDFWKMIWEQNSNIIVMLTREEENFKtKCDKYWPDKdEERYGNFIVKFDNNITIPDILIRR-EFTLENL
.|.||| .. . | .| | ... .||.|..... .|.| .||| | ....| | . | .. | || .. . ....| |
syvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkk.sgdykeygkmfvNnrkVekaeeektryviEvl
KDNKTR----KIYHFqyTTWPDHGTPVSTTGFLKFVSFV--DHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydEKKQAPSINlpKLVVEMRNER
.. . ..|.. | |... ||. . | . | ..| . ..|. |.|| |.|.. | | .|...| |. .| .|..|
Pegcsnsvlanvyvl..tnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavavekl.....qkgkepnik..eivksiRsqR
PGMVQTRDQYRFCYLAISEAMNTVLKKEQKKRK
| .|.. .|| . |.|. . . ..|...|.|
pravdslkQyvslyialllyikkkvtkpeekkk
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 236-348 | 3.2e-18 | 60.3 | In-house | 88-194 (440) | alignment | ||
Range on Protein: 236-348
Range on HMM: 88-194/440.0
NKTRKIYHfqYTTWPDHGTPVSTTGFLKFVSFVDHEK---RSGPIVVHCSAGIGRSGTFVAIHSIVAkfakhydEKKQAPSINLPKLVVEMRNERPGMVQ
..| | || | |||.| | . ||.. |.. . .||..|||||| ||.| .|. ||. | |.. |.. .. |||.|| |||
srtlkqyh..yqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilr.......eakrsdqidifsfinsmrnnrpqmvq
TRDQYRFCYLAISEAM
| .|| | . |. |..
tpeqyafvheavlegl
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 51-254 | 3.8e-18 | 60.0 | In-house | 34-235 (244) | alignment | ||
Range on Protein: 51-254
Range on HMM: 34-235/244.0
ALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDDIIVSNNNNNNNNNEKRIKRNSIGSSGQSDVMSNSSDEEDHggSGDEGTTLSDYINASFIN
|. . | |||| |.|||.|||| .. . . | . | |.| . . . | | . . . | . .|. ||||||.
avlsanatknryinilpfdetrvilssskkegsdyinanyiqgsqniirpdpsvmkdafnpnnswknregaglpfdfnrv..plskgsmgntyinasfvg
----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENfktkcDKYWPDKDE-ERYGNFI-VKFDNNITIPDILIrREFTLENLKDNKTRKIYHF
|| || || .| .|||||. |. |..|.| ||. |.|||| . | | . | | . . . .| .. .| .. . . |
clgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdseplewyeeditvtltdrdefknika.snleiesdmneshqaltmf
QYTTWPDHGT
| . || ||
qisnwpsdgt
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 241-344 | 1.3e-16 | 55.3 | In-house | 217-340 (350) | alignment | ||
Range on Protein: 241-344
Range on HMM: 217-340/350.0
IYHFQYTTWPDHGTPVSTTGFLKFVS----FVD--------HEKRSGPIVVHCSAGIGRSGTFVAIHSIVA------KFAKHYDEKKQAPSIN--LPKLV
.|..|. |.| .. . .|. . ..| ...|| ||.||||||.|| ||.|.. |.. . |.. . ..| .. . .|
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv
VEMRNERPGMVQTRDQYRFCYLAI
|.|. | |||. ||. |.| |.
nelrkqrismvqnldqfifiYeal
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 142-264 | 2e-16 | 54.3 | In-house | 79-203 (332) | alignment | ||
Range on Protein: 142-264
Range on HMM: 79-203/332.0
DYINASFINN---G-TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD--EERYGNFIVKFDNNITiPDILIRREFTLEnlKD
||||| .. | || | . . . ||.|. ||.| ||.| . |. | |||.||| | ..| . |. . . .|| | . |. |
GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkefvk.rniletrllels..kG
NKTRKIYHFQYTTWPDHGTPVSTtGFLKF
|.| ...|... | . .|. || .
nethrvlhykvfGwtettlpkye.dflal
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 140-348 | 1.3e-14 | 48.5 | In-house | 68-279 (303) | alignment | ||
Range on Protein: 140-348
Range on HMM: 68-279/303.0
LSDYINASFINNGT---YICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEerYGNFIVKFDNNITIPDILIRREFTLENLK-D
| || ||... . | || || | |||.|| ||. . ...| . | | | .| ... . .| .. . . . ..| |
dssyihasyleldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqd..flkfeersirvgefkrvelgdgwvlkvlsvs
NKTRK--IYHFQYTTWPDHGTPVS-TTGFLKFV----SFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSivAKFAKHydekKQAPSINLPKLVVEMRNERP
| . | .. .| .|| | . |.| . |.. . | | | .| ||.||| . . |... | .. .|..| | . .|| |
ngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfet..ahlslh....seqasldlvkclenvrngrl
GMVQTRDQYRFCYLAISEAM
|| |. . | ..| .
havqnlsqfsvvytllaehv
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 268-346 | 2.2e-14 | 47.9 | In-house | 241-313 (319) | alignment | ||
Range on Protein: 268-346
Range on HMM: 241-313/319.0
VDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVakfaKHYDEKKQapSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISE
.... ||.||||| |.||.|. .| . .. .| |. |...|.|| .|..| |.|..|| | | .||
sgtresqGPlvvhcsdGvGrtGlviasdiai....rsleeskr..svdiPqlvssvrrdrasavltkeqyefiykvlse
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 57-216 | 8e-14 | 45.7 | In-house | 49-168 (349) | alignment | ||
Range on Protein: 57-216
Range on HMM: 49-168/349.0
KLKNRYSNVLPFEETRVKINIDDDDDDEddNEDDIIVSNnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdeGTTLSDYINASFIN------
||||...||.| .|||.. . |. .. | ||||| ...
faknrykdilPyehsrvklkkslksskv..ikastsesd.........................................sgklddyinanylkltrisv
NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWpdkDEERYGNFIVKFDNN
. ||.|| || |. ||.|.| .. .... |. ..|. |||.|| .| | |. ||. |
ekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiyw...qelsysnitvklqns
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 260-344 | 2.1e-13 | 44.8 | In-house | 214-291 (297) | alignment | ||
Range on Protein: 260-344
Range on HMM: 214-291/297.0
GFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydekKQAPSINlpKLVVEMRNERPGMVQTRDQYRFCYLAI
||. |. . |. ...||||||.|||| | . |.|| | |. | .. .. .|..|. .||| .|. ..| |.
vflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrk.....kripdva..ailsilreqrarlvqtleqfellydav
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 242-353 | 1.8e-12 | 42.8 | In-house | 70-182 (194) | alignment | ||
Range on Protein: 242-353
Range on HMM: 70-182/194.0
YH----------FQYTTWPDHGTPVSTTGFLKFVSFVDH---EKRSGPIVVHCSAGIGRSGTFVAIHSIVAkfakhYdekkqapSINLPKLVVEMRNERP
|. . .||.||. |. |.|...||. |. .| ..||| ||.||.||.|| . | . ... . . .| ||
YdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyr.....l.......gmsaeeAialfrekRp
GMVQTRDQYRFCYLAISEAMNTVLK
|.....|... . .| .. ||
gaipnqdyleallkrykelrkavla
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 237-340 | 4.9e-11 | 37.4 | In-house | 79-168 (182) | alignment | ||
Range on Protein: 237-340
Range on HMM: 79-168/182.0
KTRKIYHFQYtTWPDHGTPvSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIvakFAKHYDEKKqApsinlpklVVEMRNERPGMVQTRDQ
. ..||.... .|.|.|.. | . | | |. . | . ||| || || | .| . . .||... .| | . .|..|| .|||.|
meqgiyvynf.gwkDygva.sleriLdivkvvafalqegkvavhChaGlGrtGvliacylv...yakrltaek.a........iklvrskrpksiqtreq
YRFC
...
velv
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 235-343 | 1.6e-10 | 34.9 | In-house | 214-339 (349) | alignment | ||
Range on Protein: 235-343
Range on HMM: 214-339/349.0
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSF----VD--------HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDE--KKQAPSIN--LP-
.| ... .|. |.| .. . .|. . .| ..... ...|||||| ||.|..| . .... . .| | . ... |
vekPyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlis
KLVVEMRNERPGMVQTRDQYRFCYLA
| |.| | ||| |. ..| |
iivnelrkqrismvqnlaqfiaiyea
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 142-254 | 3.7e-10 | 34.2 | In-house | 14-126 (130) | alignment | ||
Range on Protein: 142-254
Range on HMM: 14-126/130.0
DYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENfktkcDKYWPDKDEER-YGNFI-VKFDNNITIPDIlIRREFTLENLKD
.||||||. |. || || .| .|||||. |. |..|.| ||. |.|||| . | . | | . | .. |.
tyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdrdefkni.kasnleiesdln
NKTRKIYHFQYTTWPDHGT
. . . || . || ||
eshqaltmfqisnwpsdgt
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 278-349 | 2.3e-09 | 31.5 | In-house | 1-65 (69) | alignment | ||
Range on Protein: 278-349
Range on HMM: 1-65/69.0
VVHCSAGIGRSGTFVAIHSivaKFAKHYDEKKqapsINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMN
|||||.| ||.|||.|| . |. || ... | || || || ..| | . |. ||.
vvhcssGtGrtGtfiaimv...emariksekl....vdifnnvqymrkcrpmmvmneneymfihdalvealk
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 277-348 | 3.2e-09 | 31.1 | In-house | 1-65 (69) | alignment | ||
Range on Protein: 277-348
Range on HMM: 1-65/69.0
IVVHCSAGIGRSGTFVAIHSivaKFAKHYDEKKqapsINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAM
.|||||.| ||.|||.|| . |. || ... | || || || .| | . |. ||.
mvvhcssgtgrtgtfiaimv...emariksekl....vdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
| 0048567 | (Phosphotyrosine protein) phosphatases II | 228-337 | 8.7e-09 | 29.9 | In-house | 17-128 (157) | alignment | ||
Range on Protein: 228-337
Range on HMM: 17-128/157.0
FTLENLKDNKTRKIYHF------QYTT-WPDHGtPVSTTGFLKFVSFVDH-----EKRSGPIVVHCSAGI---GRSGTFVAIHSIVAKFAkhydekkqap
|.| ..... . ..| .| . . |.| | . . . .|. ... |.....|.|||.|| ||..|... . |
fallprlpkslynalyFsiddglvyedfffdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgf..........
siNLPKLVVEMRNERPGMVQTRDQY
. . . .| |||.| ||..
..tpeeaiaplrivrpgsvpfrdas
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 18-86 | 1.1e-08 | 29.5 | In-house | 10-81 (293) | alignment | ||
Range on Protein: 18-86
Range on HMM: 10-81/293.0
EHFNNHP--TCIDKEFNFILQKTELRALETDK-FRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDD
|.|..| .. | ...| . ||.|...|. .| .|.|. ||||.|.||....|||.. .|....|
ekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDY
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 19-85 | 1.8e-08 | 28.8 | In-house | 17-77 (319) | alignment | ||
Range on Protein: 19-85
Range on HMM: 17-77/319.0
HFNNHPTCIDKEFNFILQKTELraletdKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
. .. | ..|||. . . .. .|.|| . .|| ||||.|.|... |||.. |. .. |
lastgetllekefkllkeavnd......tfdsaskeenkkknryqnilaydrtrvvlseldgvegsd
|
|||||||||
| PTEN_1 | 244-293 | 2.8e-08 | 28.8 | In-house | 97-149 (196) | alignment | |||
Range on Protein: 244-293
Range on HMM: 97-149/196.0
FQYTTWPDHGTPVSTTGFLKFVSFVDHEKR---SGPIVVHCSAGIGRSGTFVA
. ..|||.| | .|| . .. . ..||| ||.||||| ||
ylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
| subfamily_CDC14_pd | Subfamily CDC14 | 253-336 | 5.3e-08 | 27.1 | In-house | 245-313 (328) | alignment | ||
Range on Protein: 253-336
Range on HMM: 245-313/328.0
GTPvSTTGFLKFVSFVDHEkrSGPIVVHCSAGIGRSGTFVAIHSIvakfaKHYDekkqapsINLPKLVVEMRNERPGMVQTRDQ
.|| | . ||.. ... .| |.||| ||.|| ||..| . . ||| .. . . .| |||.| . |
stP.sdaivkkfleiaeka..eGaiavhCkaGLGrtGtLiacylm.....khyr.......ftaaeaiawlricrPGsvigpqq
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 26-85 | 1e-07 | 26.4 | In-house | 21-75 (318) | alignment | ||
Range on Protein: 26-85
Range on HMM: 21-75/318.0
CIDKEFNFILQKTElralETDKFRSaLEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
...|.. . ...| .. ...| || || |||| |.|....||||.. ... . |
llseeyerlsrsee....tvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsD
|
|||||||||
| PTPc_motif_SM00404 | 258-296 | 1.5e-07 | 26.4 | In-house | 63-102 (140) | alignment | |||
Range on Protein: 258-296
Range on HMM: 63-102/140.0
TTGFLKFVSFVDH-EKRSGPIVVHCSAGIGRSGTFVAIHS
. . | ..|.. ||. | ..||| ||. ||.|... .
skyldkvldfienaekkggkvlVHCqaGvSRSatliiaYl
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 24-85 | 1.6e-07 | 25.4 | In-house | 309-367 (564) | alignment | ||
Range on Protein: 24-85
Range on HMM: 309-367/564.0
PTCIDKEFNFILqktELRALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
| ...||. . . |...| .| . ||| |||.||.|..|..||... .... |
mtgleleFqrLa...takeieleefavatkpknkkknrfsnilalescrvvlsairakeesd
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 238-295 | 1.9e-07 | 26.0 | Pfam-A | 37-94 (133) | alignment | ||
Range on Protein: 238-295
Range on HMM: 37-94/133.0
TRKIYHFQYTtWPD-HGTPVStTGFLKFVSFVDH-EKRSGPIVVHCSAGIGRSGTFVAIH
. .| .... | . | .| . . |.|.. |.. . ..||| ||| ||.|... .
kseieylrip.vedetetkis.keleeavefiekaeqkgkkvlVHCqaGisRSatliiaY
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 238-295 | 1.9e-07 | 26.0 | In-house | 37-94 (133) | alignment | ||
Range on Protein: 238-295
Range on HMM: 37-94/133.0
TRKIYHFQYTtWPD-HGTPVStTGFLKFVSFVDH-EKRSGPIVVHCSAGIGRSGTFVAIH
. .| .... | . | .| . . |.|.. |.. . ..||| ||| ||.|... .
kseieylrip.vedetetkis.keleeavefiekaeqkgkkvlVHCqaGisRSatliiaY
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 28-85 | 2.1e-07 | 26.1 | In-house | 3-57 (284) | alignment | ||
Range on Protein: 28-85
Range on HMM: 3-57/284.0
DKEFNFILQKTELRAletDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
..|| .|. | . ... || .|. ||||...||.. .|||.. |.|....
eeefeellsltvkll...lslsvallpenlsknRykdilpydhsRVklksldgdleds
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 43-87 | 2.8e-07 | 24.7 | In-house | 31-75 (315) | alignment | ||
Range on Protein: 43-87
Range on HMM: 31-75/315.0
LETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDN
.. . |.| | | |||| |.||....|||... ||. |.|
PdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyi
|
|||||||||
| subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 141-258 | 3e-07 | 23.5 | In-house | 55-158 (169) | alignment | ||
Range on Protein: 141-258
Range on HMM: 55-158/169.0
SDYINAsfinngtyictqgpllntivdfwKMIWEQNSNIIVMLTRE--EENFKTKCDKYWPDK---DEERYGNF-IVK---FDNNITIPDILIRREFTLE
|||||| .|||| |. .||.| .|| . . | | | . |. .. |.. . |. . .
sdyina.......................rmiwetnasvivvlgdtddknnfwpekedyqlhpavilgewytdslyvrtdkvhantsgveglfevsmvih
NLKDNKTRKIYHFQYTTWPDHGTPVST
. .|. | |. ..|.|||. | | |
sydddvteklsllhystwpqngvpqsp
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 25-98 | 3.4e-07 | 24.6 | In-house | 26-95 (306) | alignment | ||
Range on Protein: 25-98
Range on HMM: 26-95/306.0
TCIDKEFNFiLQKTELRALETDkfRSALEAKNKLKNRYSNVLPFEETRVKINiDDDDDDEDDNEDDIIVSNNNN
. . .||. ||..| . | . . . ..|| |||| |.|||..|||... ... ..| . ..| .. ..
agfeeefee.lqqeeakkllsr..kegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkg
|
|||||||||
| subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 141-258 | 5e-07 | 22.7 | In-house | 54-157 (169) | alignment | ||
Range on Protein: 141-258
Range on HMM: 54-157/169.0
SDYINAsfinngtyictqgpllntivdfwKMIWEQNSNIIVMLTRE--EENFKTKCDKYWPDK---DEERYGNF-IV---KFDNNITIPDILIRREFTLE
|||||| .|||| |. .||.| .|| . . | | | . | |.. | . . |. . ..
sdyina.......................rmiwetnasvivvlGdtddknnfwpekedyqlhpavilGewytdslyvrtdkvhpntsgveglfevslvih
NLKDNKTRKIYHFQYTTWPDHGTPVST
. .|. |... ..|.|||. | | |
sydddvteqlsllhystwpqngvpqsp
|
|||||||||
| subfamily_PTPMT1_pd | Subfamily PTPMT1 | 231-297 | 6.6e-07 | 23.9 | In-house | 64-130 (171) | alignment | ||
Range on Protein: 231-297
Range on HMM: 64-130/171.0
ENLKDNKTRKIYHFQYTTWpDHGTPVSTTGFLKFVSFVDHEKRSGPIV-VHCSAGIGRSGTFVAIHSI
.. .. | . ..|..|. |. ... .| | |..... .| | ||| || |||.| || . .
nsteewkklgveqlqlatv.DfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylm
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 151-211 | 7.6e-07 | 22.8 | In-house | 235-293 (440) | alignment | ||
Range on Protein: 151-211
Range on HMM: 235-293/440.0
NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREeeNFKTkCDKYWPDKD-EERYGNFIV
. ..|.|| || |..|||... . . |.|| . | || | ||| . .| | |
knafiatqmpldstvldfwrlvhdyristiimlnql..ndkt.csiywpvntrsvtfgpftv
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 22-85 | 7.8e-07 | 23.5 | In-house | 14-80 (297) | alignment | ||
Range on Protein: 22-85
Range on HMM: 14-80/297.0
NHPTCIDKEFNFILQKTELRALETDKFRSALEAKNK---LKNRYSNVLPFEETRVKINIDDDDDDED
. .| ..|. . . . |.. | . . ... |..| |.||.|.||.. |||..| .|| | |
dfatlvqknrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsD
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 16-80 | 9.8e-07 | 22.3 | In-house | 10-71 (563) | alignment | ||
Range on Protein: 16-80
Range on HMM: 10-71/563.0
IIEHFNNHPTCIDKEFNFILQKTELRALETDkfrSALEAKNKLKNRYSNVLPFEETRVKINIDDD
... . . . ...||. . ..| . |... .. . .|| ||||.|.......|||.. .
vaslhadgdigfseefealqsetiskdldae...hsqkpenkrKnRylnivaydrsRvklsplpg
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 29-92 | 1.1e-06 | 22.7 | In-house | 12-76 (290) | alignment | ||
Range on Protein: 29-92
Range on HMM: 12-76/290.0
KEFNFILQK-TELRALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDDII
|||. . . ....| .. . .. . .|. |||| ..||....||... .......| ..|
kefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfi
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 25-85 | 1.3e-06 | 22.9 | In-house | 27-85 (298) | alignment | ||
Range on Protein: 25-85
Range on HMM: 27-85/298.0
TCIDKEFNFILQKTElrALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
| ..||. . . .. .|... . | . .|| ||||....... .|| .. .|.|.. |
tgyalefqrlnsvss..eieeeekevarkpenkkkNRyadiialdssRvvLekedadeesd
|
|||||||||
| subfamily_DSP23_pd | Subfamily DSP23 | 257-338 | 1.3e-06 | 23.1 | In-house | 66-136 (148) | alignment | ||
Range on Protein: 257-338
Range on HMM: 66-136/148.0
STTGFLKFVSFVDH-EKRSGPIVVHCSAGIGRSGTFVAIHSIvakfaKhydEKKqapsINLPKLVVEMRNERPGMVQTRDQYR
. .|| |. |... . ||| | ||.||..| . . | |.| . . . |.|. ||| |.| .| .
aleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylv.....k...erk....laaaeaiaevrrlrpgsvetveqek
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 44-98 | 1.6e-06 | 21.8 | In-house | 33-87 (392) | alignment | ||
Range on Protein: 44-98
Range on HMM: 33-87/392.0
ETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDDIIVSNNNN
. . ..| . |. |||| |.||....|||... || |.| . | | .|.
diypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdne
|
|||||||||
| Spore_III_AF | Stage III sporulation protein AF (Spore_III_AF) | 53-127 | 2.1e-06 | 14.1 | Pfam-A | 87-163 (188) | alignment | ||
Range on Protein: 53-127
Range on HMM: 87-163/188.0
EAKNKLKNRYSNVLPFEETRVKINIDDDDDDED--DNEDDIIVSNNNNNNNNNEKRIKRNSIGSSGQSDVMSNSSDE
. ....... .. . .. .|....... ... .| .. |...........|..|. .||.. .|. ......
rlekqieellkleygiktvdvevevaeeqesrkfaikevvvtvkeaetgktktgkkvkpvaigqeaeskpgaeeats
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 40-76 | 2.6e-06 | 21.9 | In-house | 20-57 (273) | alignment | ||
Range on Protein: 40-76
Range on HMM: 20-57/273.0
LRAL-ETDKFRSALEAKNKLKNRYSNVLPFEETRVKIN
|| | .|. ... ...|| |||| ||||..|||||..
lrelkpldtcevgkkkenkdknryrnvlPydetrvklg
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 126-181 | 2.7e-06 | 21.1 | In-house | 58-114 (347) | alignment | ||
Range on Protein: 126-181
Range on HMM: 58-114/347.0
DEEDHGGSGDEgttLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIV
|. . . |. ||||| |. . || || || .|. |||||. . .|
peksknsradd...vetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
|
|||||||||
| PTPlike_phytase | Inositol hexakisphosphate | 196-298 | 3.1e-06 | 21.9 | Pfam-A | 80-148 (149) | alignment | ||
Range on Protein: 196-298
Range on HMM: 80-148/149.0
KywpdkdeerygnfivkfdnnitipdilirreftleNLKDNKTRKIYHFQYT--TWPDHGTPVStTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVA
. .. .... . ....| . .|. | . .||... .|. .|..|.|| ||. |...
e...................................evyeeelaegfgvkYvRipitdeqapee.edvDafvrlikslprdtalvfnCqaGrgRTTtamv
IHSIV
| ...
iadLl
|
|||||||||
| PTPlike_phytase | Inositol hexakisphosphate | 196-298 | 3.1e-06 | 21.9 | In-house | 80-148 (149) | alignment | ||
Range on Protein: 196-298
Range on HMM: 80-148/149.0
KywpdkdeerygnfivkfdnnitipdilirreftleNLKDNKTRKIYHFQYT--TWPDHGTPVStTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVA
. .. .... . ....| . .|. | . .||... .|. .|..|.|| ||. |...
e...................................evyeeelaegfgvkYvRipitdeqapee.edvDafvrlikslprdtalvfnCqaGrgRTTtamv
IHSIV
| ...
iadLl
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 314-348 | 3.2e-06 | 21.1 | In-house | 364-398 (418) | alignment | ||
Range on Protein: 314-348
Range on HMM: 364-398/418.0
INLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAM
.|| .|...|..|||||| .|| ||| .| . .
fnlfsivlklreqrpgmvqqleqylfcyktildei
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 27-77 | 3.5e-06 | 21.0 | In-house | 12-59 (287) | alignment | ||
Range on Protein: 27-77
Range on HMM: 12-59/287.0
IDKEFNFILQKTelrALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINI
.|||.. . . . | |..| | . ||||..|||...||| .
vdkevdalkeds...esstatfkaaeelaavkknryadvlPiddtrvllsa
|
|||||||||
| subfamily_DSP19_pd | Subfamily DSP19 | 261-300 | 3.7e-06 | 21.3 | In-house | 75-114 (152) | alignment | ||
Range on Protein: 261-300
Range on HMM: 75-114/152.0
FLKFVSFVDHEKRS-GPIVVHCSAGIGRSGTFVaIHSIVAK
. . . |... ... | ..|||.||. || ..| | ...|
lkealdFieearskdgavlvHCnAGvSRsasvv.iaylmkk
|
|||||||||
| DUF2457 | Protein of unknown function (DUF2457) | 69-143 | 4.5e-06 | 12.9 | Pfam-A | 47-122 (458) | alignment | ||
Range on Protein: 69-143
Range on HMM: 47-122/458.0
EETRVKINIDDDDDDEDDNEDDIIVSNNNNNNNNNEKRIKRNSIGSSGQSDVMSNSSDEEDH-GGSGDEGTTLSDY
|| . . |.||...||..|. ............ .| .|. | .|.| . | || . |||
eealeeedededdeedddddDeddddedddeddeddelddddstladassaddGnetdneagfaeSdDesddgsdy
|
|||||||||
| subfamily_DSP1_pd | Subfamily DSP1 | 235-295 | 5.2e-06 | 20.6 | In-house | 55-116 (163) | alignment | ||
Range on Protein: 235-295
Range on HMM: 55-116/163.0
DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE-KRSGPIVVHCSAGIGRSGTFVAIH
|| ....... . |. . .. | . . |.|. | | . .|| ||| || |.. ..
dnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclay
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 20-81 | 7.3e-06 | 20.0 | In-house | 10-68 (288) | alignment | ||
Range on Protein: 20-81
Range on HMM: 10-68/288.0
FNNHPTCIDKEFNFILQKTELRaleTDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDD
. | .||.|. . || . . |. |. .. |||. ..||....|||.. ||
mldgktaldkkfkeleqkqdke...arkrsiaiaklyseknrsrdilPyDhnRvklrgskDD
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 40-86 | 7.9e-06 | 20.1 | In-house | 30-77 (288) | alignment | ||
Range on Protein: 40-86
Range on HMM: 30-77/288.0
LRALE-TDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDD
| ||| |.. . .|.|. |||| |.||..|.|||.. .. ...|
LaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDY
|
|||||||||