Gene cdc14 in Drosophila melanogaster

Synonym: CDC-14, CDC14, CG7134, Dmel\CG7134, Dmel_CG7134, cdc14

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily CDC14
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP014_AA protein Get Run
DmelP014_AA_10-162 phosphatase_domain Get Run
DmelP014_AA_181-340 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CDC14_pd Subfamily CDC14 12-340 1.7e-168 554.6 In-house 2-327 (328) alignment 
Range on Protein: 12-340
Range on HMM: 2-327/328.0
CASEMQEDRLYFVAFKKniKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTKLNAKCHANKKIVHYTSMNPAKRLNAAYLIGSYAIIYL
.|.|. ||||||....|  |||.| ..||||||.|..|||||.||||||...|||||.|||.||.....|.||||.|||..  || |||.|||.||.|||
nalelledrlyfatlrk..kPkstselhyfsvddelkyenfyadfGPlnlavlyrycvklnkkLkseekaskkivlytsadskkranaalligayaviyl

NKTPQEAYRPLVAGEIPAYTRFCDASYGPSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPHQKSKtLPNGYPC
.||..||||.| |.| |....|.|||||....|..|||.|..|.|.||.||....||| ||||..|||||||||||||.||.|..|||.||| | .|||.
kktaeeayraleaaetppfvpfrdasygsasykltlldvlkgvekalqkgfldledfdleeYekyervenGDfnwivPdkflalagPhnksk.ledgypl

HAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIA
||||....|||.||||||.|||.|.|.|..|..||||||||||||||||||||.||||.|.|...|||||||||||||||.||..|.||||.||| ||||
haPeklleyfrknnvttvvrLnkklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaia

WLRLCRPGSVIGHQQQWMEDKQSWLWSEG
|||.||||||||.||...|.||..||.||
wlricrPGsvigpqqkfleekqaalwleg
DSPn Dual specificity protein phosphatase, N-terminal half 15-156 1.2e-56 181.3 Pfam-A 2-140 (141) alignment 
Range on Protein: 15-156
Range on HMM: 2-140/141.0
EMQEDRLYFVAFKKniKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTKLNAKCHANKKIVHYTSMNPAKRLNAAYLIGSYAIIYLNKT
|. |||||||..||  |||.| ||||||.|||..||.||.||||||....||.|.|||.||... ...||||.|||... || |||.|||.||.|.|...
eliedrLyfvslkk..kpkktenthyfsiDeelvYepfyadFGPlnlaqiyrfcvklnkkLkeaelkkkkivlytsldekkranaalLigaYavivlkls

PQEAYRPLVAGEiPAYTRFCDASYGPSNFKISLLDCLNAVHK
|.||..|| ..| |... |.|||||.|......||||....|
peealkplesve.psllpFrDAsygestyeltildclkglek
0048567 (Phosphotyrosine protein) phosphatases II 10-166 1.7e-48 158.8 In-house 4-157 (157) alignment 
Range on Protein: 10-166
Range on HMM: 4-157/157.0
LVCASEMQEDRLYFVAFkkNIKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTKLNAKCHANKKIVHYTSMNPAKRLNAAYLIGSYAII
.. ..|. .|||||...   ..||...|..|||.|....||.|. ||||||. .|||...||| .|.   .|.|.|........ || ..|.|||.|.|.
ngdlieiipdrlyfall..prlpkslynalyFsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlil

YLNKTPQEAYRPLvAGEIPAYTRFCDASYGPSNFKISLLDCLNAVHKGLQAGFFNFN
.|..||.||..|| .   | .  |.||||..|.....|||.|....|.|. ||....
hlgftpeeaiapl.rivrpgsvpfrdasyllslynltlldvlyGllkAlelgfldle
0049772 (Phosphotyrosine protein) phosphatases II 132-336 1.4e-40 135.4 In-house 68-270 (314) alignment 
Range on Protein: 132-336
Range on HMM: 68-270/314.0
RFCDASYGPSNFKISLLDCLNAVHKgLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQK---------------------FIAFCGPHqksktlpngyp
 . . .|  ...  . |... . .. |. ....|....  .|.....|..||.|.... .                     .. ..|..           
pvsgsdyinasyvdgflkfIatqgp.leitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng...........

CHAPERYFSYFRdnnvttvirlnAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSICET--TKGAIAVHCKAGLGRTGS-LIGAYIMKHYGFTAL
.. ..... ...             .| .. ||..|. .... . |||.|.......|| ..|.  ..|...|||||| ||||. .. ||.||..|... 
neptaadlellk...........eelydpelferlgikylripvpDgsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsle

EAIAWLRLCRPgsvIGHQQQWMEDKQSWL
||....||.||   |. .. ..|  . ..
ealedvrlkRp...inpnpgfieqleqye
0038934 (Phosphotyrosine protein) phosphatases II 172-331 5.2e-40 132.5 In-house 5-168 (194) alignment 
Range on Protein: 172-331
Range on HMM: 5-168/194.0
EYEYFERVENgdfnwIVPQKFIAFCGPHQKSKT-LPNGYPCHAPERYFSYFRDNN--VTTVIRLN--AKVYHASSFENAGFDHKDLFFID-GSTPSDAIM
.....|||..     |.. .||||..|...| .   ... ...|| ...|....|  ...||.|.   ..|... ||.||... .|.|.| |..||..|.
rwlkyervgd.....iitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleil

KKFLSIC-----ETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVigHQQQWMED
..||...     | ..|..|||||||||||| |..||.....|..| ||||..| .|||..   .|...|.
lrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgai..pnqdylea
0041856 (Phosphotyrosine protein) phosphatases II 168-340 2.3e-38 126.9 In-house 2-173 (182) alignment 
Range on Protein: 168-340
Range on HMM: 2-173/182.0
FDAEEYEYFERVENGDFNWIVPQKFIAFCGPHQKsKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKK
.| ..|. . ..... ... .  ...... |...   . .|.. . ..... .......||...|.   | .. .|..|. ...|.. |...|.  .. .
ldknrysdilpydhsrdldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpdldelld

FLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWMEDKQSWLWSEG
|. ...  .|...|||.||.||||.|..||.||..|... ||....| .|||.||  .| ...  . ... ..
fieevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll
0048567 (Phosphotyrosine protein) phosphatases II 179-337 1.5e-37 123.2 In-house 2-138 (157) alignment 
Range on Protein: 179-337
Range on HMM: 2-138/157.0
VENGDFNWIVPQKFIAFCGPHQKSktlpngypchaperyfsyfrdnnvttvirlnaKVYHASSF-ENAGFDHKDLFFIDGstPSD--------AIMKKFL
.||||...|.|........|. ..                                ..|.|  |  ..|. . |.|| .|  | .         ...|||
kengdlieiipdrlyfallprlpk................................slynalyFsiddglvyedfffdfG..PlnlailyrFilklnkfl

SICETTKGAIAVHCKAGL---GRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWMEDKQSWLW
.|.| ...||||||||||   |||. |||.|...|.|||. ||||.||..|||||......... ......
kilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslynltl
0045098 (Phosphotyrosine protein) phosphatases II 150-339 5.3e-37 123.1 In-house 2-274 (278) alignment 
Range on Protein: 150-339
Range on HMM: 2-274/278.0
CLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIV----------------------PQKFIAFCGPHQksktlpngypcHAPERYFSYFRDNNVT
. .|. . |. ..|..  ..  |.... ...|.|.|...                      |.||||. ||..           .  . .. .......|
ealasldlllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlp...........stvadfwrmlwelgit

TVIRLNAKVYHA----------------------------------------------SSFENAGFDHKDL-FFIDGSTPSDAIMKKFLSICE-------
....|.  |. .                                              ...|..|. | .. .. |...||. |.| ||...|       
vivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealk

-------------TTKGAIAVHCKAGLGRTGSLIGAYIMKHY---GFTALEAIAWLRLCRPG-SV-IGHQQQWMEDKQSWLWSE
               .| ..|||.||.|||| |..||.|...   |...|||...|| .||| .| . .|...... . .|.. 
llaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelllr
0040438 (Phosphotyrosine protein) phosphatases II 140-326 6.1e-37 123.0 In-house 2-264 (317) alignment 
Range on Protein: 140-326
Range on HMM: 2-264/317.0
PSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIV----------------------------------PQKFIAFCGPHQKsktl
. ...  |||.|.  ...|. .|... ... ..|...|..||.|.|...                                  ..||||. ||...    
vldlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpn....

pngypchAPERYFSYFRDNNVTTVIRLNAKVYH------------------------ASSFENAGFDHKDLFF-------------------IDGSTP-S
         | .. .. ...||....|.  ..                          | .|.||. .  | .                    |...| |
.......tvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvpps

DAIMKKFLSICETT----KGAIAVHCKAGLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQ
  .. .||.....     .| ..|||.||.||||..|.||.|     |..|... ||...|| .|||.|   .|
pdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeq
0044763 (Phosphotyrosine protein) phosphatases II 165-340 3.2e-36 120.0 In-house 4-174 (178) alignment 
Range on Protein: 165-340
Range on HMM: 4-174/178.0
FNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPhqksktlpngypchapERYFSYFRDNNVTTVIRLNAKVY------HASSFENAGFDHKDLFFIDGS
.. .. ...|..||... ....|.|  ... ..|                .... .......|....|.  ..      ..  .|.||. .. . . |..
rtrvllsnleglersdyinaseilpglylgslpp................addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhg

TPS-DAIMKKFLSICE----TTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWMEDKQSWLWSEG
.|. .... .|. ..|    . .|...|||.||.||.|.|. ||.||..|... |||...| .||..   .|...... ...|..|.
vpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRpivpnpgqlrqLyefelrllkes
0050432 (Phosphotyrosine protein) phosphatases II 124-327 5e-36 120.0 In-house 5-288 (308) alignment 
Range on Protein: 124-327
Range on HMM: 5-288/308.0
AGEIPAYTRFCDASYGPSNFKISLLDCLNAVHKGLQAGFFN------FNDFDAEEYEYFERVENGDFNW-------------------------------
.. .. .. |.|.|. .|..|.|.||.|... | |. |...      .. .. .||......||.|.|.                               
ldallelllfrdtsilvsslklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkldegsdYInAsyvdgyss

IVPQKFIAFCGPHqksktlpngypCHAPERYFSYFRDNNVTTVIRLNAKVYH-----ASSFENA---GFDHKDLFFI-----------------------
..|.||||. ||.            .  | .. .. ..||.....|.  |.      |  . .    |. . . |..                       
klprkfIatqgPl...........pntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgd

---------------DGSTPSD-AIMKKFLSICETT--KGAIAVHCKAGLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQQ
               |...|.. .|. .|| .....  .| |.|||.||.|||| .| ....     |..|....||...|| .|||.|.. .| 
gesrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqy
0043336 (Phosphotyrosine protein) phosphatases II 139-326 4.4e-35 116.9 In-house 3-265 (278) alignment 
Range on Protein: 139-326
Range on HMM: 3-265/278.0
GPSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIV----------------------------------PQKFIAFCGPHQKskt
. ...   ||..| .....|...|.....|. ..|......||.|.|...                                  |.||||. ||...   
svkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe...

lpngypchAPERYFSYFRDNNVTTVIRLNAKV--------------------------------------------YHASSFENAGFDHKDLFfiDGSTP
         .| .. ......|||...|.  |                                            ..  |..  .. ...    |...|
........tvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp..dhgvp

-SD----AIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQ
 |      ..|......|. .|...|||.||.|||| .|..|..     |..|....||...|| .|||.|   .|
eslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsq
0045450 (Phosphotyrosine protein) phosphatases II 130-326 7.6e-35 116.5 In-house 5-292 (307) alignment 
Range on Protein: 130-326
Range on HMM: 5-292/307.0
YTRFCDASYGPSNFKISLLDCLNAVHKGLQaGFFNFNDFDAEEYEYFERVENGDFNWI------------------------------------------
. .|.|| .. . ... |||.|. ..|  .  ......|.  ||......||.|.|..                                          
lslfidalkllllvllllldfltgllkefe.kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgy

-VPQKFIAFCGPHQKsktlpngypchAPERYFSYFRDNNVTTVIRLNAKVYHASS------------------------------------------FEN
 ...||||. ||...            .| .. ......||....|.  |....                                           ...
dlkrkfIatqgPlpe...........tvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtg

AGFDHKDLFF---IDGSTPSD-AIMKKFLSICET------TKGAIAVHCKAGLGRTGSLIGAYIMKHYG--------FTALEAIAWLRLCRPGSVIGHQQ
 .. .. ...    |...|.. ... .|. ....       .| ..|||.||.||||..|.||.|....        ...|||...|| .|||.|   .|
esrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeq
0039614 (Phosphotyrosine protein) phosphatases II 131-327 1.2e-34 115.6 In-house 2-278 (297) alignment 
Range on Protein: 131-327
Range on HMM: 2-278/297.0
TRFCDASYGPSNFKISLLDCLNAVHKGLQAGFFNFNDFDA----EEYEYFERVENGDFNWIV------------------------------------PQ
. . ||..... ...| ||.|. ..| .. ...  . ..     ..|......||.|.|...                                    ..
lplrdallesipiplsvldlllllekansktllllefeellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltr

KFIAFCGPHQKsktlpngypchAPERYFSYFRDNNVTTVIRLNAKVYHASSF----------------ENAGFDHKDLFF--------------------
||||. ||...            .| .. ......||....|.  |..   .                .. ...|.| ..                    
kfIatqgPlpe...........tvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqy

---IDGSTP-SDAIMKKFLSICET------TKGAIAVHCKAGLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQQ
    |...| | ... .|| ....       .| ..|||.||.||||..|.||.|     |..|...|||...|| .|||.|   .| 
tgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqy
0043147 (Phosphotyrosine protein) phosphatases II 171-329 4.9e-34 112.9 In-house 2-152 (172) alignment 
Range on Protein: 171-329
Range on HMM: 2-152/172.0
EEYEYFERVENGDFNWiVPQKFIAFCGPhqksktlpngyPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLS
.|......... |... .|..|||..||            ..  . .. .......|....|.  .| .. .|  |. .  | . |...|. ... .||.
degsdyinasyldlyy.ipdrfiatqgp...........lrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvpllelllefle

ICET-----TKGAIAVHCKAGLGRTGSLIGAYIMKhYGFTALEAIAWLRLCRPGSVIGHQQQWM
....      .|...|||.||.|||| |. ||.|. .|....||.|..| .|||.|   .|.. 
fidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrf
0040439 (Phosphotyrosine protein) phosphatases II 172-326 8.7e-30 99.5 In-house 2-234 (249) alignment 
Range on Protein: 172-326
Range on HMM: 2-234/249.0
EYEYFERVENGDFNWIV----------------------------------PQKFIAFCGPHQKsktlpngypchAPERYFSYFRDNNVTTVIRLNAKV-
||......||.| |...                                  ...|||. || ..           . | .. .......|....|.  | 
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe...........tvedfwrmlwelgitvivmLtslve

--------------------------------------------YHASSFENAGFDHKDLFfiDGSTP-SDAIMKKFLSICET------TKGAIAVHCKA
                                            |. .|..  .. . |.   | ..| | ... .|. ....      ..| ..|||.|
lgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp..dhgvppsfedlldfieavrkaleelpkggpvlVHCsa

GLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQ
|.|||| .|.||.|     |..|....||...|| .|||.|   .|
GvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeq
0049260 (Phosphotyrosine protein) phosphatases II 208-328 1.1e-29 98.5 In-house 16-140 (152) alignment 
Range on Protein: 208-328
Range on HMM: 16-140/152.0
GYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSI-----CETTKGAIAVHCKAGLGRTGSLIGAYIMKhY
|. ..  . .. .......||...|.  .. .  ... .. .. |.. |...|..... .|| .     ..  .| ..|||.||.|||| |. ||.|. .
gpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.l

GFTALEAIAWLRLCRPGSVIGHQQQW
|....||.|..| .|||.|. ..| .
gvsleeavalvrekRpgavpnpgqlr
0051082 (Phosphotyrosine protein) phosphatases II 183-330 1.3e-29 98.1 In-house 7-145 (151) alignment 
Range on Protein: 183-330
Range on HMM: 7-145/151.0
DFNWIVPQkFIAFCGPHQksktlpngypchapeRYFSYFRDNNVTTVIRLNAKV---YHASSFENAGFDHKDLFFIDGSTPSD----AIMKKFLSICETT
.|... .  .... ||..               ... ........|.. |. ..   |... ....|...... ..| ..|.     .....||.... .
nfsyvtgg.lyrsggpla...............dflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldk

-KGAIAVHCKAGLGRTGSLIGAYIMKhYGFTALEAIAWLRLCRPGSVIGHQQQWME
 .| ..|||.||.|||| |...|.|. .|... ||....||.|||.|. .||....
kngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfq
0042113 (Phosphotyrosine protein) phosphatases II 173-326 2.8e-29 97.7 In-house 1-231 (245) alignment 
Range on Protein: 173-326
Range on HMM: 1-231/245.0
YEYFERVENGDFNWI----------------------------------VPQKFIAFCGPHQKsktlpngypchAPERYFSYFRDNNVTTVIRLNAKVYH
|......||.|.|..                                  ...||||. ||...            .| .. .......||...|.  ...
ysvallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe...........tvedfwrmlwelgittivmLteeeel

-------------------------------------------ASSFENAGFDHKDLFFIDGSTPS-DAIMKKFLSICET-----TKGAIAVHCKAGLGR
                                            ....  .. .  | . |...|. .... .||.....      .| ..|||.||.||
grvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgR

TGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQ
|| .|.||.|     |..|... ||...|| .|||.|   .|
tGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsq
0037934 (Phosphotyrosine protein) phosphatases II 180-327 3.7e-29 97.4 In-house 35-231 (243) alignment 
Range on Protein: 180-327
Range on HMM: 35-231/243.0
ENGDFNWIVPqKFIAFCGPHQKsktlpngYPCHAPERYFSYFRDNNVTTVIRLNAKV------------------------------------------Y
 |... ...| ..||..||...         ..... .. .. ....|... |.  |                                          .
inanliyvtp.rliatqgPlpe.......tveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenl

HASSFENAGFDHKDLFFIDGSTPS-DAIMKKFLSI------------CETTKGAIAVHCKAGLGRTGSLIGAYIMKHY-GFTALEAIAWLRLCRPG-SVI
 .. ..  .. .  | . |...|.  ... .||..            .. ..| ..|||.||.|||| || ||.|... |....||...|| .||| .| 
dlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavq

GHQQQ
  .| 
tpsqy
0036282 (Phosphotyrosine protein) phosphatases II 180-326 2.5e-28 94.4 In-house 8-158 (174) alignment 
Range on Protein: 180-326
Range on HMM: 8-158/174.0
ENGDFNWIVPqKFIAFCGPHQksktlpngypchaperYFSYFRDNNVTTVIRLNAKVYHA------------SSFENAGFDHKDLFFIDGSTPSDAIMKK
 . |...| | ..||..||..                .. .......|||..|.  ..              ...|. |. ...| . |...|...|. .
spldlsyitp.rliagqgpla................fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsille

FLSICETT-----KGAIAVHCKAGLGRTGSLIGAYIMKHYGF-TALEAIAWLRLCR---PGSVIGHQQ
|....|.      .| ..|||.||.|||| |..||.|..... .. .|....| .|   ||.|.  .|
fvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQ
0046846 (Phosphotyrosine protein) phosphatases II 177-327 4.4e-27 90.4 In-house 5-162 (176) alignment 
Range on Protein: 177-327
Range on HMM: 5-162/176.0
ERVENGDFNWIVPQKFIAFCgPHQKSKTLPNgypchAPERYFSYFRDNNVTTVIRLNAK--------VYHASSFENAGFDHKDLFFIDGSTPSDAIMKKF
......|...|... ..  . |  .   ||.       . .. .......|.|..|.           .. . .|..|. .. | . |...|..... ..
llgldldldyinanlilgsr.piatqgplpr.....tladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllel

LSICETTK---GAIAVHCKAGLGRTGSLIGAYIMKH-YGFTALEAIAWLRLCRP-GSVIGHQQQ
| ....     | ..|||.||.|||| |. ||.... .|....||.|..| .|| |.|   .| 
lefirealkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQy
PTEN_1 173-332 2.1e-26 87.9 In-house 14-188 (196) alignment 
Range on Protein: 173-332
Range on HMM: 14-188/196.0
YEYFERVENGDFNWIVPQKFIAFCGPHQKsKTLPNGYPCHAPE--RYFSYFRDNNVTTVIRLNAKV------YHASSFENAGFDHKDLFFIDGSTPSDAI
..  | .... ... .  .. |.. | .. .. .. | .....  ...  .  ...|.|..|. .       |. ..|.. |. .... . |  .|| . 
alptelldltyitsriiamgkapsrpllq.eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslse

MKKFLSICETT------KGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCR-PGSVI-GHQQQWMEDK
. ...  ..        .....|||||||||.| .. || |.....|| ||....| .| ||..  ..|....|  
lfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyf
0048179 (Phosphotyrosine protein) phosphatases II 216-327 6e-26 86.3 In-house 20-134 (144) alignment 
Range on Protein: 216-327
Range on HMM: 20-134/144.0
RYFSYFRDNNVTTVIRLNAKvYHASSFENAGFDHKDLFFIDGSTPSD-AIMKKFLSICETT---KGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIA
. . .......||||.|. . |.  ..|. |. .  | . | ..|.. ... .|| ..|.    .| ..|||.||.||||.|. ||.||..|... ||.|
ldlellkklgittvinltee.yepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkklglsleeala

WLRLCRPGSVIGHQQQ
..| .|||.|.  .| 
lvrsrrpgavpnpgql
0048076 (Phosphotyrosine protein) phosphatases II 217-327 3.8e-25 83.6 In-house 21-132 (145) alignment 
Range on Protein: 217-327
Range on HMM: 21-132/145.0
YFSYFRDNNVTTVIRLnakVYHASSFENAGFDHKDLFFIDGSTPSD-AIMKKFLSICETT---KGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAW
 . ...|...|||..|    .  . .|. |. .  | . | ..|.. ... .|| ..|.    .| ..|||.||.||||.|..||.|...|... ||...
dlellkdlgittvlnl...tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealel

LRLCRPGSVIGHQQQ
.| .|||.|.  .|.
vrsqrpgavpnpgql
0047943 (Phosphotyrosine protein) phosphatases II 166-326 5.2e-25 83.9 In-house 23-260 (273) alignment 
Range on Protein: 166-326
Range on HMM: 23-260/273.0
NDFDAEEYEYFERVENGDFNWI------------------------------VPQKFIAFCGPHqksktlpngypCHAPERYFSYFRDNNVTTVIRLNAK
. ..  .|......||.|.|..                              ...||||. ||             .  | .. .. ..||.....|.  
slkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPl...........pntvedfwrmvweqnvrviVmLtel

VYHAS---------------------------SFENAGFDHKDLF-------------------FIDGSTP-SDAIMKKFLSICET------TKGAIAVH
|.                               ...... .  |                    . | ..| | ... .|. ....       .| ..||
velgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVH

CKAGLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQ
|.||.||||..| ....     |..|...|||...|| .|||.|.  .|
CsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeq
0046845 (Phosphotyrosine protein) phosphatases II 186-326 7.1e-20 67.0 In-house 73-262 (284) alignment 
Range on Protein: 186-326
Range on HMM: 73-262/284.0
WIVPQKFIAFCGPHQK------------------------SKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAG-------FDHKDLFF
.....||||. || ..                        ..     ..   .|  . .. |  ||.. . . . |    .|          . .. . .
tyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhy

---IDGSTP-SDAIMKKFLSICETT------KGAIAVHCKAGLGRTGSLIGAYIMKHY--------GFTALEAIAWLRLCRPGSVIGHQQ
    | ..| | ... .|| ....       .| |.|||.||.|||| .| .......        |...|||...|| .|||.|   .|
tswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleq
0051429 (Phosphotyrosine protein) phosphatases II 163-327 1.1e-18 63.4 In-house 7-214 (272) alignment 
Range on Protein: 163-327
Range on HMM: 7-214/272.0
FNFNDFDAEeyeyfervengdFNWIVPQKFIAFCGPHQKSktlpngypchapERYFSYFRDNNVTTVIRLNAKVYHAS---SFENAGFDHKDLFFIDGST
.|..| .              .....| ....  ||.. .            .. | ........|.. |   .....   ... .|...  | ..| |.
iNardvggy............grvvkpgrlyrsggplplt............aadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsa

PSD----------------------------------------------------AIMKKFLSICETtKGAIAVHCKAGLGRTGSLIGAYIMKhYGFT--
|.                                                       ....|... . .|.. |||.|| .||| .. ....  .|..  
ptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsle

------------ALEAIAWLRLCRPGSVIGHQQQ
            ..||...|| .|||.|   .| 
tivddYlltnlyleeaveelraqrpgavqteeqy
0051299 (Phosphotyrosine protein) phosphatases II 187-326 1.5e-18 62.8 In-house 89-274 (288) alignment 
Range on Protein: 187-326
Range on HMM: 89-274/288.0
IVPQKFIAFCGPHQksktlpngypcHAPERYFSYFRDNNVTTVIRLNAKV-------------------------------------------------Y
  ..||||. || .           .  | .. .  ..||.....|.  |                                                 .
nlkrkfIatqgPlp...........ntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldg

HASSFENAGFDHKDLFfiDGSTPS-----DAIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIM-----KHYGFTALEAIAWLRLCRPGSVIGHQQ
.  |..   | ...    | ..|.      ...... . .. ..| ..|||.||.|||| .| ....     |..|...|||...|| .|||.|.  .|
dgesrtvthfhytnwp..dhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeq
subfamily_PRL_pd Subfamily PRL 215-332 3.1e-18 60.3 In-house 24-145 (151) alignment 
Range on Protein: 215-332
Range on HMM: 24-145/151.0
ERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSICE-----TTKGAIAVHCKAGLGRTGSLIGAYIMkHYGFTALEA
|.. . .. ..|.||.|     |.....|..| . .|| | ||..|........|....     ..| ..|||| |||||.  |.   ..   |..  .|
ekfieelkkeevktvvrvceptydteklekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalali.eaGmkyeda

IAWLRLCRPGSVIGHQQQWMEDK
. ..|  | |..  .| ...|. 
vefirekrrgainskqlkfleky
0036941 (Phosphotyrosine protein) phosphatases II 190-326 3.1e-17 58.3 In-house 78-265 (297) alignment 
Range on Protein: 190-326
Range on HMM: 78-265/297.0
QKFIAFCGPHQksktlpngypcHAPERYFSYFRDNNVTTVIRLNAKVYH---------------------------------ASSFENAGFDHKD-----
.||||  || .           .  | ..    ..|||... |.  |                                    ...    .  .|     
rkfIatqgPlp...........ntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgnge

---------LFFIDGSTPS-DAIMKKFLSICET------TKGAIAVHCKAGLGRTGSLIGAYIM--------KHYGFTALEAIAWLRLCRPGSVIGHQQ
         .   | ..|.  |.. .|.  ...       .| . |||.||.||.|..|.|..|        |..|.. |||. .|| .|||.|   .|
srtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleq
DSPc Dual specificity phosphatase, catalytic domain 263-321 1.6e-14 48.9 Pfam-A 60-118 (133) alignment 
Range on Protein: 263-321
Range on HMM: 60-118/133.0
AIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSV
  ...|.. .|. .. ..|||.||. |...|| ||.|| ..... ||.. ..  |.  .
eeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskis
DSPc Dual specificity phosphatase, catalytic domain 263-321 1.6e-14 48.9 In-house 60-118 (133) alignment 
Range on Protein: 263-321
Range on HMM: 60-118/133.0
AIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSV
  ...|.. .|. .. ..|||.||. |...|| ||.|| ..... ||.. ..  |.  .
eeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskis
PTPc_motif_SM00404 263-322 9.1e-14 46.5 In-house 67-124 (140) alignment 
Range on Protein: 263-322
Range on HMM: 67-124/140.0
AIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRpgSVI
  ...|.. .|...|.. |||.||. |...|| ||.|. ..... ||.  ..  |  . |
dkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerR..pii
subfamily_DSP23_pd Subfamily DSP23 214-327 1e-13 46.2 In-house 21-135 (148) alignment 
Range on Protein: 214-327
Range on HMM: 21-135/148.0
PERYfSYFRDNNVTTVIRLNAKVYHASSfENAGFDHKDLFFIDGSTPSDAIMKKFLSICET---TKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAI
|..|  |. |. |  .. |  .    .     .   . |   |   |.   ...|. . |     . |..|||  | ||||...  |..|. ...| |||
pdqy.rylldlgvrylvslteegrphve.atpnltlvrlriddyhppaleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeai

AWLRLCRPGSVIGHQQQ
| .|  |||||   .|.
aevrrlrpgsvetveqe
subfamily_PTPDC1_pd Subfamily PTPDC1 274-326 2.1e-13 45.1 In-house 112-164 (182) alignment 
Range on Protein: 274-326
Range on HMM: 112-164/182.0
TTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQ
 ..|..|||| ||||||| || .|.. .  .|| .||  .|  || |.  ..|
lqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreq
subfamily_RNGTT_pd Subfamily RNGTT 190-321 4.4e-11 36.8 In-house 16-158 (189) alignment 
Range on Protein: 190-321
Range on HMM: 16-158/189.0
QKFIAFCGPH--QKSKTLPNGYpCHAPERYFSYFR--DNNVTTVIRLN--AKVYHASSFENAGFDHKDLFFI-DGSTPSDAIMKKFLSICET-----TKG
.||..|  |   . .. |..    . |.  .||..  ....  || |    . |... .|. |  .. |     | .|.   .|.| ...|.     .. 
ekflpfktplskrydddlaeen.rfepsmllsylktlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffkknpee

AIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSV
 |.|||. |  ||| || .|....  . . .|.|  . .||  .
vigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGi
subfamily_DSP11_pd Subfamily DSP11 217-319 5.2e-10 33.5 In-house 46-158 (178) alignment 
Range on Protein: 217-319
Range on HMM: 46-158/178.0
YFSYFRD--NNVTTVIRLN--AKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLS-------ICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFT
 ..  ..  ...  || |    . |. ..... |  .. |.    ..|.. ..||| .        .. ..  |.|||  |. ||| ||  |.... |. 
LleklqeknkklGLvidltntdryykkkeltdegvkylklncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegye

ALEAIAWLRLCRpG
. .||  .  .| |
pedaieafeear.G
subfamily_PTPMT1_pd Subfamily PTPMT1 239-328 1.2e-09 32.8 In-house 66-158 (171) alignment 
Range on Protein: 239-328
Range on HMM: 66-158/171.0
ASSFENAGFDHKDLFFIDGS-TPSDAIMKK---FLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIgHQQQW
  .... | ..  |  .|   .|. . ..|   |..   ...  . |||||| ||...|...|.||.. ..  ||.  |. .|.   . ...||
teewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirl.akkqw
subfamily_DSP3_pd Subfamily DSP3 231-316 1.2e-08 28.8 In-house 52-137 (162) alignment 
Range on Protein: 231-316
Range on HMM: 52-137/162.0
RLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLC
  .|. |. ....  |.. .| . .| |.  .  .|   .  ....| . |||..|. |   |. ||.| .  .|. |||   |  
dtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkk
subfamily_DSP12_pd Subfamily DSP12 267-316 1.2e-08 29.4 In-house 73-122 (155) alignment 
Range on Protein: 267-316
Range on HMM: 73-122/155.0
KFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLC
.|.. .  ..||. |||.||. |  ... ||.||....   .|.  ..  
dFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkek
subfamily_PTEN_pd Subfamily PTEN 266-307 7.7e-08 27.5 In-house 106-145 (184) alignment 
Range on Protein: 266-307
Range on HMM: 106-145/184.0
KKFLSicETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTAL
.|.|.  | .|  ..|||||| |||| || ||..|.  ..  
ekwle..edkknvvvvHCkaGkGRtGvlivayllksllleka
PTPc_DSPc_SM00012 265-301 1.6e-07 26.8 In-house 29-64 (105) alignment 
Range on Protein: 265-301
Range on HMM: 29-64/105.0
MKKFLSICETtKGAIAVHCKAGLGRTGSLIGAYIMKH
.||. . .|. .. . |||.|| |||| .. ..|. .
vkknknkses.skpvvVhCsaGvgRtgtfvaldillq
subfamily_DSP19_pd Subfamily DSP19 266-319 1.7e-07 25.7 In-house 79-132 (152) alignment 
Range on Protein: 266-319
Range on HMM: 79-132/152.0
KKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPG
 .|.    ...||. |||.||  |. |.. ||.||.   .  ||.  .|  || 
ldFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpc
subfamily_DSP14_pd Subfamily DSP14 272-318 1.7e-07 25.4 In-house 79-125 (157) alignment 
Range on Protein: 272-318
Range on HMM: 79-125/157.0
CETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRP
 ....|.. |||.||  |  ||  ||.||.   .  ||  ... .||
vkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRp
subfamily_DSP1_pd Subfamily DSP1 266-318 2.1e-07 25.2 In-house 85-137 (163) alignment 
Range on Protein: 266-318
Range on HMM: 85-137/163.0
KKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRP
 .|.  .....| . .||.||. |  .|. ||.||.  ..  ||  . .  |.
iefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRs
subfamily_DSP10_pd Subfamily DSP10 272-318 4.1e-07 24.0 In-house 88-134 (159) alignment 
Range on Protein: 272-318
Range on HMM: 88-134/159.0
CETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRP
   .   . |||.||. |  ... ||.||| . .  .|  . . .||
arkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrp
subfamily_Slingshot_pd Subfamily Slingshot 267-317 4.8e-07 23.3 In-house 87-137 (169) alignment 
Range on Protein: 267-317
Range on HMM: 87-137/169.0
KFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCR
||.. . ...  . |||| |. |. | . || ||.||..  ||.....  |
kfiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerr
subfamily_MSG5_pd Subfamily MSG5 272-309 6.4e-07 22.6 In-house 95-132 (165) alignment 
Range on Protein: 272-309
Range on HMM: 95-132/165.0
CETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEA
 .. .  | |||. || |. ||| |||||.|...  .|
atskrkkilvhcqcglsrsaslivayimkyynlslrda
subfamily_STYX_pd Subfamily STYX 265-314 1.1e-06 21.8 In-house 85-134 (166) alignment 
Range on Protein: 265-314
Range on HMM: 85-134/166.0
MKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLR
.|.|.  .  . | . || .||. |. .|. ||||. ||.   || |...
vkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvq
subfamily_Dicty-DSP-Subfam1_pd Subfamily Dicty-DSP-Subfam1 279-313 2.4e-06 20.3 In-house 69-103 (128) alignment 
Range on Protein: 279-313
Range on HMM: 69-103/128.0
IAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWL
. |||. |  ||| .. .|.||. |.   .|. | 
lyvhcecgcdrtgevlasyvmkykgydlkkalewd
subfamily_Dicty-DSP19-1_pd Subfamily Dicty-DSP19-1 279-313 2.4e-06 20.3 In-house 68-102 (128) alignment 
Range on Protein: 279-313
Range on HMM: 68-102/128.0
IAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWL
. |||. |  ||| .. .|.||. |.   .|. | 
lyvhcecgcdrtgevlasyvmkykgydlkkalewd
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 267-326 3.5e-06 20.7 In-house 212-276 (302) alignment 
Range on Protein: 267-326
Range on HMM: 212-276/302.0
KFLSICETTKGAIAVHCKAGLGRTGSLIGA----YI-MKHYGFTALEAIAWLRLCRPGSVIGHQQ
. |  ||. | .. ||| ||.||||.|.       . .|.     |. .  .| || |.|  .||
dilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqq
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 258-299 4.6e-06 20.6 In-house 201-243 (305) alignment 
Range on Protein: 258-299
Range on HMM: 201-243/305.0
STPSDAIMKKFLSICETTKGAIAVHCKAGLGRTGSLIG-AYIM
  ..|  . ..|  . ..|| |.||| ||.|||||..   ||.
vpaadlailellekarpskgpivvhcsagigrtgsvvmleyil
subfamily_DSP8_pd Subfamily DSP8 267-317 4.7e-06 20.2 In-house 84-134 (159) alignment 
Range on Protein: 267-317
Range on HMM: 84-134/159.0
KFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCR
.|.  . ...| . ||. ||  |  ... |||||.  ..  ||  ...  |
efidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekr
Y_phosphatase Protein-tyrosine phosphatase 267-321 4.9e-06 21.5 Pfam-A 157-220 (235) alignment 
Range on Protein: 267-321
Range on HMM: 157-220/235.0
KFLSICETTK----GAIAVHCKAGLGRTGSLIGAYIMKHY-----GFTALEAIAWLRLCRPGSV
...  .|..|    | . |||.|| ||||... . |. .       .  |...  || .|||.|
dlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv
Y_phosphatase Protein-tyrosine phosphatase 267-321 4.9e-06 21.5 In-house 157-220 (235) alignment 
Range on Protein: 267-321
Range on HMM: 157-220/235.0
KFLSICETTK----GAIAVHCKAGLGRTGSLIGAYIMKHY-----GFTALEAIAWLRLCRPGSV
...  .|..|    | . |||.|| ||||... . |. .       .  |...  || .|||.|
dlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv