Gene CG15528 in Drosophila melanogaster

Synonym: Dmel\CG15528, Dmel_CG15528, CG15528

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP14
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP018_AA protein Get Run
DmelP018_AA_41-188 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP14_pd Subfamily DSP14 39-194 1.5e-66 217.2 In-house 2-154 (157) alignment 
Range on Protein: 39-194
Range on HMM: 2-154/157.0
TPFPGLSRITPSLILCGAAAVVPAYMDKLGVSCVINVAPELPDTPLPSQKnplYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSA
.....||.|||||.|.|.||. .....| .....|||..|||.|.|....   .......|..|..|||||||.|| ||||. .||.||.||||||||||
pelaalsqitpsLflsgvaalskellkkkkitliinvtvelpntklkdie...rvkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSA

SLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRGSSSVAMVY
|||||||||.. .|||||||.|...||..|||.||..||..||..|.|.|||.||.
slclaylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgkssvkmvd
0044763 (Phosphotyrosine protein) phosphatases II 38-188 6.5e-41 135.3 In-house 17-174 (178) alignment 
Range on Protein: 38-188
Range on HMM: 17-174/178.0
HTPFPGLSRITPSLILCGAAAVV-PAYMDKLGVSCVINVAPELP------DTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVH-LSGGCTLIH
 ......|.|.| |.|... ..  .... .||.....|...||.      |   |.. .  ||.|   | .. || .||.|. ..|||..  .||..|.|
rsdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVH

CVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPqVRPNSGFFQQLRRYEQQLRGSS
| |||.||..|..|||||. |.|| ||...|.. || . || |. .||...|..|.. |
CsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkes
subfamily_DSP10_pd Subfamily DSP10 45-187 3.3e-38 125.1 In-house 15-156 (159) alignment 
Range on Protein: 45-187
Range on HMM: 15-156/159.0
SRITPSLILCG-AAAVVPAYMDKLGVSCVINVAPELPDTPLPsqKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
|.. | |.|     |   . .|.|....|.||....| .     ..  | || ..| |. .| ..|.|| . |||.. .|   |.|| ||.||||.. .|
sqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefee..ealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRGS
||||| ..||..|||.|.  || . || .|  || ..|..|. |
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks
PTPc_motif_SM00404 44-182 2e-36 120.0 In-house 2-139 (140) alignment 
Range on Protein: 44-182
Range on HMM: 2-139/140.0
LSRITPSLILCGAAAVV-PAYMDKLGVSCVINVAPELPDTplPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCL
 |||.| |.|... . . || ..|||.. ||||. | . |   ....  .|.|  .|  . .|.|..|...| ||... .||  |.|| |||||||.|..
psrilphlylgskskaqnpallkklgithvinvteevslt..kensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatlii

AYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
||||.  ..||.|||. |.  ||...|| .|..||  ||.
aYlmryrqlslaeayefvkerRpiispnlnfvrqLieyek
subfamily_DSP19_pd Subfamily DSP19 44-184 6.5e-35 114.7 In-house 12-150 (152) alignment 
Range on Protein: 44-184
Range on HMM: 12-150/152.0
LSRITPSLILCGA-AAVVPAYMDKLGVSCVINVAPELPDTpLPsqKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCL
.. ..|.| |    .|     ... ..  ..||| ..|..  |  |.  || |   | .| || ....|| | |||.. . |. |.|| ||||||||. .
vgeveprlylgsqdvaadkeilkekkitHilnvatgvpnv.fp..kdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvvi

AYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
|||||.  .||.||.. |...|| ..||.||..||..||..|
aylmkkeelsleealelvrearpcikPneGFikqLkeyeael
DSPc Dual specificity phosphatase, catalytic domain 52-183 1.2e-34 114.0 Pfam-A 2-133 (133) alignment 
Range on Protein: 52-183
Range on HMM: 2-133/133.0
ILCGAAAVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGM
.|... .  .| ..|||.. ||||. | | . . ....  ||||  .| .| ...|...|| . ||... .|.  |.|| ||.||||.|..|||||  ..
ylgskstaslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknl

SLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
||.|||..|.  |....|| || .||. ||..
slneAyefvkerrskispnagflrqLleyerk
DSPc Dual specificity phosphatase, catalytic domain 52-183 1.2e-34 114.0 In-house 2-133 (133) alignment 
Range on Protein: 52-183
Range on HMM: 2-133/133.0
ILCGAAAVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGM
.|... .  .| ..|||.. ||||. | | . . ....  ||||  .| .| ...|...|| . ||... .|.  |.|| ||.||||.|..|||||  ..
ylgskstaslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknl

SLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
||.|||..|.  |....|| || .||. ||..
slneAyefvkerrskispnagflrqLleyerk
subfamily_DSP6_pd Subfamily DSP6 46-186 2.6e-34 112.0 In-house 16-156 (158) alignment 
Range on Protein: 46-186
Range on HMM: 16-156/158.0
RITPSLILCGA-AAVVPAYMDKLGVSCVINVAPELPDTpLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAY
.|.| | |  | .|     ..||... |.||...||..   ....  ||.| ..|. . .|||.| || ..|.| . .    |.|| ||.|||  ..|||
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnk.feesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlay

LMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRG
|||.  .|| .||. |.. .... ||  |..||  .|..|| 
lmkklalslndaydlvkkrksnisPnfnfmgqlldferslrl
subfamily_DSP12_pd Subfamily DSP12 45-183 5e-34 111.9 In-house 3-142 (155) alignment 
Range on Protein: 45-183
Range on HMM: 3-142/155.0
SRITPSLILCGAAAVVP-AYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
|||.| | | |..||.  . ...|... |. |. |  ..  .....  .. | . |. |.|. .|.||| | |||    .|  |.|| ||||||.....|
srilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviA

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
||||. ..|| .|.| |....|...|| || .||. .|. 
YlmkkeklslekAlklvkekkpeiepNegFleQLklfekm
subfamily_DSP1_pd Subfamily DSP1 42-185 1.1e-33 110.7 In-house 17-157 (163) alignment 
Range on Protein: 42-185
Range on HMM: 17-157/163.0
PGLsRITPSLILCGAA-AVVPAYMDKLGVSCVINVAPELPDTplpSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASL
|   .|.. | | ..  |     ...||.. ..||. ||...    ..   | ..  .|... |. ..|.|. . |.||. ..|  |||| ||.|||..|
Pve.kildfLylGsetvasnleiLkslgitailnvskeldnv...fedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstl

CLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
|||||||.  .|| ||.. |.  |. ..|| || .|| .||..| 
claylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll
0049772 (Phosphotyrosine protein) phosphatases II 39-184 2.6e-33 111.5 In-house 167-273 (314) alignment 
Range on Protein: 39-184
Range on HMM: 167-273/314.0
TpfpglsritpslilcgaaavvpaymdklgvscvinvaPELPDTPLPSQKNPLYLRIMAQDrSEVDLAKHFDEAADLIEEVhLSGGCTLIHCVAGVSRSA
                                      .|| | .|... .  ||||   |  ...| ..|||. ..|||.   ||..|.|| ||..|..
k.....................................eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtg

S-LCLAYLMKHAGMSLREAYKHVQAIRPqVRPNSGFFQQLRRYEQQL
. ...|||||. |.||.||...|...|| ..|| ||..||..||..|
tfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyefil
0048076 (Phosphotyrosine protein) phosphatases II 45-185 2.7e-32 106.8 In-house 5-143 (145) alignment 
Range on Protein: 45-185
Range on HMM: 5-143/145.0
SRITPSLILCGAAAVV-PAYMDKLGVSCVINVapeLPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
|.|.|.| | .  ...  ... .||. .|.|.    ....|.....  ||..   |... ||.....|. ..|||.. .||..|.|| |||.|...|..|
seilpglylgslptaldlellkdlgittvlnl...tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
|||.. |.|| ||...|.. ||.. || |....|...|..|.
ylmlllgvsleealelvrsqrpgavpnpgqlrflyefelell
0041856 (Phosphotyrosine protein) phosphatases II 37-185 3.7e-32 106.8 In-house 14-173 (182) alignment 
Range on Protein: 37-185
Range on HMM: 14-173/182.0
DHTPfpGLSRITPSLILCGAA---------------AVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDlakhFDEAADLIEEVHL
||..  .|..|...|.|..                 |    .. .||.....|...|| .  |  . .  ||..   | .  |    .||. |.||||. 
dhsr..dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevle

SGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRP--QVRPNSGFFQQLRRYEQQLR
.||..|.|| |||.|...|..|||||. |.||.||.|.|.  ||   ..|| .|| ||  .| .|.
eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll
0043147 (Phosphotyrosine protein) phosphatases II 56-185 5.1e-32 106.3 In-house 32-161 (172) alignment 
Range on Protein: 56-185
Range on HMM: 32-161/172.0
AAAVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVdLAKHFDEAADLIEE--VHLSGGCTLIHCVAGVSRSASLCLAYLMKhAGMSL
  | . ... .||.....|. ..| |..| .. .  ||..   | .   |.....|. ..|.|  .  .||..|.||.|||.|.. |..||||.  |.||
tladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsl

REAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
 ||...|.. ||.. .| .. ..|. .|..|.
eeavalvrekRpgavqnpsqyrflyyfeklll
0048179 (Phosphotyrosine protein) phosphatases II 45-184 5.3e-32 105.9 In-house 5-144 (144) alignment 
Range on Protein: 45-184
Range on HMM: 5-144/144.0
SRITPSLILCGAAAVV-PAYMDKLGVSCVINVAPElPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
|.|.|.| |..  ...  ... |||...|||...|  . . . . .  ||..   |..  ||.....|. ..|||.. .||..|.|| |||.|...|..|
seilpglylgslptaldlellkklgittvinltee.yepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaa

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
||||. |.|| ||...|...||.. || |....|..||..|
ylmkklglsleealalvrsrrpgavpnpgqlrfLleyekll
0046846 (Phosphotyrosine protein) phosphatases II 39-186 7.4e-31 102.6 In-house 7-174 (176) alignment 
Range on Protein: 39-186
Range on HMM: 7-174/176.0
TPFPGLSRITPSLILCGA-----------AAVVPAYMDKLGVSCVINVAPE--------LPDTPLPSQKNPLYLRIMAQDRSEVDLaKHFDEAADLIEEV
.....|..|...|||...            |   ... .||...|.|.  |          . |.  . .  ||..   | .  || ....|. ..|.|.
gldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirea

HLSGGCTLIHCVAGVSRSASLCLAYLMKH-AGMSLREAYKHVQAIRP-QVRPNSGFFQQLRRYEQQLRG
  .||..|.||.||..|.. |..|||...  |.|. ||...|...|| .. .. .. ..|...|..|..
lkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefellllk
0036282 (Phosphotyrosine protein) phosphatases II 39-186 8.1e-31 102.4 In-house 7-171 (174) alignment 
Range on Protein: 39-186
Range on HMM: 7-171/174.0
TPFPGLSRITPSLILCGAAAVVPAYMDKLGVSCVINVAPELPDT------------PLPSQKNPLYLRIMAQDRSEVDLAKhFDEAADLIEEVHLS--GG
 .. .||.||| ||.... .   ... .||...|... .| ..               ... .  ||...  |... ||.. ..|. ...||....  ||
aspldlsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpgg

CTLIHCVAGVSRSASLCLAYLMKHAGM-SLREAYKHVQAIR---PQVRPNSGFFQQLRRYEQQLRG
..|.|| |||.|.. |..||||.. .. ||..|...|...|   |.. .. .....|. .|..|.|
pvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekllsg
subfamily_DSP8_pd Subfamily DSP8 43-185 8.7e-31 100.6 In-house 14-155 (159) alignment 
Range on Protein: 43-185
Range on HMM: 14-155/159.0
GLSRITPSLILCGAAAVV-PAYMDKLGVSCVINVAPELPDTPLPSQKNplYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLC
|. ||.. | |     |.    ..|||.| |.|.  . |..   ....  .||.  .|. . .|   ||.. . |. .. . |. |.|. || ||||.. 
gptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkesk..flrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatva

LAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
.||.||.  ||| |||..|.  || . ||  | .||  ||..|.
iayimktlemsldeayrfvkekrptispnlnflgqLleyekelk
PTEN_1 33-185 3.7e-30 100.2 In-house 27-192 (196) alignment 
Range on Protein: 33-185
Range on HMM: 27-192/196.0
STLEDHTPFPGLS---RITPSLILCGAAAVV--PAYMDKLGVSCVINVAPELPDtP------LP-SQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVH
| . ... .|...   .| ..|... .  |.     ... |. .|.|...| .. .          ...  ||... .|    .|...||.....|| . 
sriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeel.sgrsydleeffksgveylhfpieDhgapslselfdicksfiewll

L--SGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
.  .|.. |.|| ||..||. .. ||||.. ... .|| ..|.. ||...|||.. ..|..|...|.
sdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaell
0049260 (Phosphotyrosine protein) phosphatases II 60-185 9.1e-30 98.7 In-house 25-150 (152) alignment 
Range on Protein: 60-185
Range on HMM: 25-150/152.0
VPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEE-VHLSGGCTLIHCVAGVSRSASLCLAYLMKhAGMSLREAYK
.  .. .||.......  .|... |   . . ||..   | .  ||. ..... ..||.  . .||..|.||.|||.|.. |..||||.  |.|| ||..
fwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeava

HVQAIRPQVRPNSGFFQQLRRYEQQLR
.|.. ||.. || |. ..|  .|..|.
lvrekRpgavpnpgqlrflyefekllk
0045098 (Phosphotyrosine protein) phosphatases II 39-185 1.4e-29 98.8 In-house 17-272 (278) alignment 
Range on Protein: 39-185
Range on HMM: 17-272/278.0
TPFPGLSRITPSLILCGAA------------------------------------------AVVPAYMDKLGVSCVINVAPELPD---------------
 . .  |.|||.| |....                                          |    .. .||.............               
lllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsl

--------------------------------TPLPSQKNPLYLRIMAQDRSEVDLA--KHFDEAADLIEEVHL--------------SGGCTLIHCVAG
                                . |.| .   .  .   | .  .|   |.|.|. . |.|..               |||..|.|| ||
tygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaG

VSRSASLCLAYLMKHA---GMSLREAYKHVQAIRPQ-VRPNSGFFQQLRRYEQQLR
|.|.. |..||||..    |..| ||.|...  ||. . .| .....| .....|.
vgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllell
0037934 (Phosphotyrosine protein) phosphatases II 43-184 2.8e-29 97.8 In-house 38-241 (243) alignment 
Range on Protein: 43-184
Range on HMM: 38-241/243.0
GLSRITPSLILCGA---------AAVVPAYMDKLGVSCVINVAPEL------------------------------------------PDTPLPSQKNPL
.|...|| ||....         .|    .. .||....... ..                                           .|.. ... .  
nliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvih

YLRIMAQD----RSEVDLAKHFDEAADLIEE-----VHLSGGCTLIHCVAGVSRSASLCLAYLMKHA-GMSLREAYKHVQAIRPQ-VRPNSGFFQQLRRY
|...   |     |  || ...||. . |||     .  ||| .|.||.|||.|.. |..||||..  |..| ||.|.... ||. . .. .....|...
yhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyea

EQQL
...|
llel
subfamily_DSP3_pd Subfamily DSP3 58-185 2.7e-28 92.7 In-house 26-158 (162) alignment 
Range on Protein: 58-185
Range on HMM: 26-158/162.0
AVVPAYMDKLGVSCVINVAPELP---D--TPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVH-LSGGCTLIHCVAGVSRSASLCLAYLMKHAGM
|    .. |||.  |.| |       |  .   .. .  || . ..|  |.|| |.|..||. |.|    . |  |.|||.|||||| | ||||| .  |
akdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlvlayLmirrkm

SLREAYKHVQAIRpQVRPNSGFFQQLRRYEQQLR
.| || ..|.. | ...||.||..||. ....|.
tlveairtvrkkR.eilPneGFlkqLaeldeelk
subfamily_DSP15_pd Subfamily DSP15 62-183 3.1e-28 92.8 In-house 21-138 (151) alignment 
Range on Protein: 62-183
Range on HMM: 21-138/151.0
AYMDKLGVSCVINVAPelpdTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQ
. ...  .. ...|       . .  |.  |. |.|.| ....| |.|.|. ..| .  | ..  |.||.||||||. |. ||||    .. |.| . ..
elLkeknithilsvhd....nakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevik

AIRPQVRPNSGFFQQLRRYEQQ
| |    || || .||. ||..
aaRsvanPnfGfkrqlkeyekt
0042113 (Phosphotyrosine protein) phosphatases II 40-184 2.9e-27 91.1 In-house 38-242 (245) alignment 
Range on Protein: 40-184
Range on HMM: 38-242/245.0
PFP-----GLSRITPSLILCGAAAVVPA-----YMDKLGVSCVINVAPELPD-------------------------------------------TPLPS
..      ...|||| .|.... .         .. .||....... .| ..                                              .|
dyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddes

QKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHL--SGGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRR
...  |...   | .. || ...... ......    |.| .|.|| |||.|.. ...||||     |. |.|| ||.|...  ||..... .....|..
revihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflye

YEQQL
....|
allel
subfamily_LRR-DSP_pd Subfamily LRR-DSP 89-184 9.6e-27 87.7 In-house 163-258 (263) alignment 
Range on Protein: 89-184
Range on HMM: 163-258/263.0
NPLYLRI-MAQDRSEVDLAKHFDEAADLIEEVHLSGGCtLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
   || |  ..|  | |. .||.|   .|||   .||  |.|| ||||||..| ..||||.  . ..||.  |.  ||...|| || .||..||..|
lfkylsiddiedvdeadisqhfeetnafieeGrkkGGv.lvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekkl
subfamily_Slingshot_pd Subfamily Slingshot 65-187 1.3e-26 87.0 In-house 41-160 (169) alignment 
Range on Protein: 65-187
Range on HMM: 41-160/169.0
DKLGVSCVINVAPELPDTpLPSQKNplYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIR
.. ||. ..||. |. .   | . .  ||.|   | .| || |...|. . ||... .|   |.||  |||||||  .|| ||. |.|| ||...|.  |
kengveyilnvtkeidnf.fpekfe..ylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerr

PQVRPNSGFFQQLRRYEQQLRGS
  ..||.||..||. ||  |. |
svikPnkgflkqleeyeGileas
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 63-183 8.9e-26 84.2 In-house 28-146 (148) alignment 
Range on Protein: 63-183
Range on HMM: 28-146/148.0
YMDKLGVSCVINVAPELpDTPLPSQkNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQA
 . .|||. ..| . |  | .|  .    || .  .|  . || . |..... .....  |.  |.|.  |||||. | |..|...  .||.||.  |. 
alkalgvtrivnatker.dnaldqr.gieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrvslkealalvks

IRPQVRPNSGFFQQLRRYEQQ
 |. |.|| || .||  .||.
krryvdpnlgfLkqLaeleqa
0040439 (Phosphotyrosine protein) phosphatases II 63-184 4.5e-25 84.1 In-house 73-245 (249) alignment 
Range on Protein: 63-184
Range on HMM: 73-245/249.0
YMDKLGVSCVINVAPELPD----------------------------------------TPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHL-
.. .||....... .. .                                         |.|  ..   .| |   |  . .. ..|... |.||.|.  
mlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrka

-----SGGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
     .||..|.|| |||.|.. ...||||     |. |..| ||.|...  ||.. .| .....| .....|
leelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
0045450 (Phosphotyrosine protein) phosphatases II 65-184 1.2e-24 83.1 In-house 128-303 (307) alignment 
Range on Protein: 65-184
Range on HMM: 128-303/307.0
DKLGVSCVINVAPELPDTPL--------------------------PsQKNPLYLRIMAQDR-----------------SEVDLAKHFDEAADLIEEVHL
 ..||...... .. ...                              ...  ....  .|                   . .. ..|.|. |.||||. 
weqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrk

------SGGCTLIHCVAGVSRSASLCLAYLMKHAG--------MSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
      .||..|.|| |||.|......||||.. .        ..|.||.|.... ||.. .| .....|......|
aleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 63-185 1.3e-24 80.0 In-house 19-142 (145) alignment 
Range on Protein: 63-185
Range on HMM: 19-142/145.0
YMDKLGVSCVINVAPELPDTPLPSQ-KNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQ
 ...||.| ..|.|     .   .. ..   | | |.|    ||..|||| .|.|.  .  |   ..||.|||||| .. .|.|||. .|.| || . |.
tlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvr

AIRPQVRPNSGFFQQLRRYEQQLR
. | .  ||  |...| . |.||.
snrllaypnvtflknllnlekqlk
subfamily_MKPLT_pd Subfamily MKPLT 88-185 2e-24 80.0 In-house 64-161 (164) alignment 
Range on Protein: 88-185
Range on HMM: 64-161/164.0
KNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
|   ||..  .| |.  |..... ||... .   |||. |.||| |.|||.|  .|.|.|  |  |.|||....  |  |.|| ||..|| ..|. . 
ksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfeelil
subfamily_MKPLV_pd Subfamily MKPLV 88-185 2e-24 80.0 In-house 64-161 (164) alignment 
Range on Protein: 88-185
Range on HMM: 64-161/164.0
KNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
|   ||..  .| |.  |..... ||... .   |||. |.||| |.|||.|  .|.|.|  |  |.|||....  |  |.|| ||..|| ..|. . 
ksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfeelil
0040438 (Phosphotyrosine protein) phosphatases II 64-222 2.3e-24 81.7 In-house 106-312 (317) alignment 
Range on Protein: 64-222
Range on HMM: 106-312/317.0
MDKLGVSCVINVAPELPD------------------------T---PlpsQKNPLYLRIMAQDR----------------SEVDLAKHFDEAADLIEEVH
. ..||...... .. ..                        .        ..  ..... .|                  . .. ...|.  |..|.|.
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee...lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavr

LS----GGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRgSSSVAMVYFASLDKEIPDILEPEYR
 .    ||..|.||.|||.|......||||     |. |... ||.|.... ||.. .. .....| ......     . .... .| .... .|.| . 
ealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl.krkltlepaselklkllklliplal

AMEDFYQRYRS
 . ........
ddvklkekelk
0051082 (Phosphotyrosine protein) phosphatases II 39-180 7.1e-24 79.5 In-house 3-149 (151) alignment 
Range on Protein: 39-180
Range on HMM: 3-149/151.0
TPFPGLSRITPSLILCGA-AAVVPAYMDKLGVSCVINVAPELPDT---PLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLS-GGCTLIHCVAG
.... .|..|. |...|.  | . ... .||.....|. .| .      .  . .  .|.|   | .. .|  .||......|..    .|..|.|| ||
sdyinfsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaG

VSRSASLCLAYLMKhAGMSLREAYKHVQAIRP-QVRPNSGFFQQLRRY
..|.. |...|||.  |.|| ||.......||  |.|| .|. ||. .
kgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal
0039614 (Phosphotyrosine protein) phosphatases II 64-185 1.5e-23 79.1 In-house 121-289 (297) alignment 
Range on Protein: 64-185
Range on HMM: 121-289/297.0
MDKLGVSCVINVAPELPD--------------------TPLPSQKNPLYL-------------------RIMAQDRSEVDLAKHFDEAADLIEEVHL---
. ..||...... .. ..                    | |  .... |                     .   | .  .......|. .|..|..    
vweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelp

SGGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
.||..|.||.|||.|......||||     |. |... ||.|...  ||..... .....|......|.
kggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell
subfamily_STYXL1_pd Subfamily STYXL1 46-186 1.7e-23 76.6 In-house 13-155 (157) alignment 
Range on Protein: 46-186
Range on HMM: 13-155/157.0
RITPSLILCGA--AAVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
 . |. .  |    |. ||    | |  ..||. .  .     ..    |.|  .|  | || ....|| ..||. . .| . |.    |.||||.. .|
evlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviia

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRG
||| .  ..|..|||...  .. |.|| .| .||...|.|| |
ylmyskkitlkkaykylkkCkenvkPnrafveqlseWekqllg
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 92-185 1.6e-21 70.3 In-house 58-153 (154) alignment 
Range on Protein: 92-185
Range on HMM: 58-153/154.0
YLRIMAQDRSEVDLAKHFDEAADLIEEVH--LSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
||..   |  . |. ...| | ..|..    .  .  |.|. .||||||.| ..|||..  .|| .|.. ..  |....|| || .|| ..|..|.
ylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdklkislslalellkdsryiikPnqGflkqleifekell
0036941 (Phosphotyrosine protein) phosphatases II 102-184 3.3e-21 71.3 In-house 180-276 (297) alignment 
Range on Protein: 102-184
Range on HMM: 180-276/297.0
EVDLAKHFDEAADLIEEVHL------SGGCTLIHCVAGVSRSASLCLAYLM--------KHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
. ..  ....  |.||.|.       ||| .|.||.|||.||.....|.||        |. |... ||.|..   ||.. .. .....|......|
dhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel
0038934 (Phosphotyrosine protein) phosphatases II 89-186 1e-20 69.6 In-house 79-178 (194) alignment 
Range on Protein: 89-186
Range on HMM: 79-178/194.0
NPLYLRIMAQDRSE---VDLAKHFDEAADLIEEVhLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLR
.  ||...  |. .    .. ..| ...| . .   .||. ..||.||..|.. |. |||... |||..||..... .|| . || .....|... ..||
gieylklpfpddgtvPsleillrfldlvdeflne.dpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykelr

G
 
k
subfamily_STYX_pd Subfamily STYX 88-182 2.4e-20 66.3 In-house 61-155 (166) alignment 
Range on Protein: 88-182
Range on HMM: 61-155/166.0
KNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
.. .|| .   | .  .. ... .  ..|..   .||  |.|  ||.||||.| .||.|.  |.  |||...||  |  . ||.|| .||. || 
drfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyea
0043336 (Phosphotyrosine protein) phosphatases II 64-183 2.4e-19 65.3 In-house 108-275 (278) alignment 
Range on Protein: 64-183
Range on HMM: 108-275/278.0
MDKLGVSCVINVAPELPD------------------------------------------TPLPSQKNPLYLRIMAQDRSEV-DLAKHFDEAADLIEEVH
. .|||...... ..  .                                             .|..   |  .   | .   .|. ..|   ...| ..
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale

LSGGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
 |.|..|.||.|||.|.. ....||.     |. |..| ||.|...  ||.  ..  ....|......
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
subfamily_MSG5_pd Subfamily MSG5 61-185 9e-19 61.2 In-house 40-161 (165) alignment 
Range on Protein: 61-185
Range on HMM: 40-161/165.0
PAYMDKLGVSCVINVAPELPDTPLPSQKnPLYLRIMAQDRSEvdLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHV
|   . |    ||||| |..|  |       |  |  .  |.  ..| . . . .|   .  .   |.||  |.|||||| .||.||. ..|||.||...
pklkellsfdlvinvakeindlellvpa.vkyyhiewehdsk..ivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydkl

QAIRPQVRPNSGFFQQLRRYEQQLR
..   .. |. |.  ||  .|  | 
ksvaddispsiglifqlmewevals
0051429 (Phosphotyrosine protein) phosphatases II 62-184 1.1e-18 63.3 In-house 39-224 (272) alignment 
Range on Protein: 62-184
Range on HMM: 39-224/272.0
AYMDKLGVSCVINVAPELPDTPLPSQ---KNPLYLRIMAQDRSEVDLAKHF------------------------------------------------D
... .||....... .|     |.      .  ||..   |.|. .   ..                                                .
wrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqe

EAADLIEEVHLsGGCTLIHCVAGVSRSASLCLAYLMKhAGMS--------------LREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
.  .|.|...  ||  |.|| ||..|.. .....|.  .|.|              |.||.....|.||..... .....|......|
allellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallel
subfamily_PTPMT1_pd Subfamily PTPMT1 93-184 7.9e-17 56.2 In-house 77-168 (171) alignment 
Range on Protein: 93-184
Range on HMM: 77-168/171.0
LRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
|..  .|  |    ..  .. ..||.|. .| .  .|| || .|||.|  .||||.  .|. || |.....|...| ..  ...|..||..|
lqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekl
0047943 (Phosphotyrosine protein) phosphatases II 107-177 1.3e-15 53.1 In-house 183-264 (273) alignment 
Range on Protein: 107-177
Range on HMM: 183-264/273.0
KHFDEAADLIEEVHL------SGGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGFFQQL
 ....  ..||.|.       |.| ...||.|||.|........|.     |. |... ||.|...  || . ..  ....|
pslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
0051299 (Phosphotyrosine protein) phosphatases II 106-172 3.4e-13 45.2 In-house 198-273 (288) alignment 
Range on Protein: 106-172
Range on HMM: 198-273/288.0
AKHFDEAADLIEEVHLS----GGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSG
  ....  |....|. .    ||....|| |||.|.. .....|.     |. |... ||.|..   ||.. ..  
pdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpe
0050432 (Phosphotyrosine protein) phosphatases II 108-173 4.7e-13 44.6 In-house 215-287 (308) alignment 
Range on Protein: 108-173
Range on HMM: 215-287/308.0
HFDEAADLIEEVHLS--GGCTLIHCVAGVSRSASLCLAYLM-----KHAGMSLREAYKHVQAIRPQVRPNSGF
....  |..|.|. |  || ...|| |||.|.. .....|.     |. |... ||.|..   ||.. ..   
speilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeq
0046845 (Phosphotyrosine protein) phosphatases II 109-171 4.3e-12 41.5 In-house 184-260 (284) alignment 
Range on Protein: 109-171
Range on HMM: 184-260/284.0
FDEAADLIEEVHLS------GGCTLIHCVAGVSRSASLCLAYLMKHA--------GMSLREAYKHVQAIRPQVRPNS
..   .....|. .      || ...|| |||.|.. .....|...         |... ||.|..   ||.   . 
pedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtl
0048567 (Phosphotyrosine protein) phosphatases II 113-173 4.8e-10 34.0 In-house 64-127 (157) alignment 
Range on Protein: 113-173
Range on HMM: 64-127/157.0
ADLIEEVHLSGGCTLIHCVAGV---SRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGF
 .... . | |.   .|| ||    .|.| |. .||..| |.. .||..... .||   |    
nkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrda
subfamily_CDC14_pd Subfamily CDC14 120-166 2.4e-07 24.9 In-house 260-306 (328) alignment 
Range on Protein: 120-166
Range on HMM: 260-306/328.0
HLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQ
  . |   .|| ||. |  .|  .||||| ...  ||  ... .|| 
ekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPG
PTPc_DSPc_SM00012 107-164 7.2e-07 24.7 In-house 27-83 (105) alignment 
Range on Protein: 107-164
Range on HMM: 27-83/105.0
KHFDEAADLIEEvhlsGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLR---EAYKHVQAIR
.....    .|.    .. ...|| |||.|.. ....... .  .. .   . .. |...|
ravkknknkses....skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelr
subfamily_DSP23_pd Subfamily DSP23 89-166 2.9e-06 22.0 In-house 51-127 (148) alignment 
Range on Protein: 89-166
Range on HMM: 51-127/148.0
NPLYLRIMAQDRSEVDlAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQ
|  . |.  .|       .  .|   ..|| .  .    .||. |  |. ..   ||.|. ...  ||   |.  || 
nltlvrlriddyhppa.leqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpg
subfamily_RNGTT_pd Subfamily RNGTT 91-183 3.1e-06 21.0 In-house 79-174 (189) alignment 
Range on Protein: 91-183
Range on HMM: 79-174/189.0
LYLRIMAQDRSEVDLAKHFDEAADLIEEVH--LSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQL-RRYEQQ
 | ..  . . |   | . .|   |.|| .   .     .||  |  |.  |  .||...  .|...| .  .  ||.   .  . ..| |||.. 
kyvklqcagkgeaPeaeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiykedylkellrrYadv