Gene Sbf in Drosophila melanogaster

Synonym: CG6939, DSbf1, Dmel\CG6939, SBF, Sbf1, dSbf1, sbf, Dmel_CG6939, Sbf

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR5
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP031_AA protein Get Run
DmelP031_AA_1152-1675 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR5_pd Subfamily MTMR5 1154-1671 4.9e-226 743.1 In-house 2-483 (483) alignment
Range on Protein: 1154-1671
Range on HMM: 2-483/483.0
VERMRERSYVQDWKRLGFDAE---SQRG-FRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHA-NGALLIRGGQPNSKSVIGM
||...||.||||.||||..|.   |.|| ||||..|..|..||||||.||.|...||..|.....||. .|.|..||||. |.|||||.|...||.|.|.
veklaerayvqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfeskgvvgl

LK--NTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNqySGMNLSMSSLMGHSSSDDRQPLTPElsrkhKNNLDISDGNKSSQGGKGGTM-KGN
||  ||.||.|..........||.||. |..|...||..||||  |....|.|.|...||||.|..|..|     ||.||||...|.||||||.|. ..|
lksantqgsstsessessksleqekylkavvnevsklsalaln..sslevslsvlasssssdkraalste.....knaldisksdkasqggkgatlkenn

PKNSLAHPFRKMRLYALGEKSQAKS-NMNVDFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLID
.|.| ....||..||.||||||.|. ...||..|.||||....|||....||||.|||.||....||. |||.|.||.|.||||||||.|||||||||.|
akeskklrarkaaLYvlgeksqlknvksevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlld

LQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTniAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLR
||.|||..|||||.|||||.||.|||.||||||.|.||.||||||||||||||..|||...|....  .|||.||||||.|||..||||.|||||||||.
lqgssvlvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqss..gfaPvFlqFLDcvhqvsrqfPlafefndfylk

FLAYHSVSCRFRTFLFDCELERSDSGIaamedkrgslnakhmfgaggmatngsddecsvypldIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNFLYS
||||||||.||||||.|.|.||..||.                                    .....|... ...|.|..|||.|||...|||||||||
flayhsvsnrfrtfllDseyerlesgl....................................lyeekaekrakkagksvwdyidrqhkrspifynflys

GDKSVTLRPQNNVAALDLWCYYTNEEL
.|.|..|||..||..|..|.||..|||
pdesevlrPssnvsslkvWdyyleeel

Myotubularin-like phosphatase domain 1137-1568 9.4e-117 382.7 Pfam-A 2-352 (353) alignment
Myotubularin-like phosphatase domain 1137-1568 9.4e-117 382.7 In-house 2-352 (353) alignment
0040695 (Phosphotyrosine protein) phosphatases II 1157-1669 6e-107 351.6 In-house 8-384 (388) alignment
Range on Protein: 1157-1669
Range on HMM: 8-384/388.0
MRERSYVQDWKRLGFDAEsqrGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHA-NGALLIRGGQPNSksvigmlknttgs
. ........||||.. .    .|||. |  |  |.||||..| |...||  ...  |.....|||  ..||. |||.|.| .|| .             
wslydilrelkrlglgld...lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplv.............

ttnaHHDVTHYPEQDKYFLALINTMPkltplalnqysgmnlsmsslmghsssddrqpltpelsrkhknnldisdgnkssqggkggtmkGNPKNSLAHPFR
    .. .. . |..|.. |.....|                                                              ...|. .    .
....glllsrsledeklleailkllp..............................................................nlskllivdlrp

KMRLYALGEKSQAKSNMNVDFCADFIPVDYPDIRQSRPAFKKLIRACmpshnTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLE
|.. .|   ..    |..  ..|..|....|.|.. | ...||..||     .|  | ... ...|.|.||..|.....|.  .|.|.||..|||..  .
klnalanralgggvenedaypnaeliflnipnihvvreslqklldac.....lnvpdslnllslleesgwldliklilelavlivklldlgnssvlvhcs

DGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTNiAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRF
|| | |.||||.|||.||||||.|.||.||.|||||.|||.||.|... .|. ...  |.|.||.|||.|.||.||||.|||||...|.|||.|..||||
dgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidsk.efsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrf

RTFLFDCELERSDSGIaamedkrgslnakhmfgaggmatngsddecsvypldirsqrapaplNRIGHSIFDYIERQHNKtpiFYNFLYSGDKSVTLRPQN
.||||..| || ....                                              .. ..|...|. .....   |.|.||. .... |.|  
gtFlfnsekerlelsv..............................................sertlslwsyllsrkse...flnplYdpsslevllpsl

NVAALDLWCYYTNE
.|  | ||..|...
svldlllWleyylr

SBF2 Myotubularin protein 582-807 6.7e-100 322.3 Pfam-A 1-225 (225) alignment
Range on Protein: 582-807
Range on HMM: 1-225/225.0
PMGPRLPEALDVRPNVQ-NSARRLEVLRICVSYIFENRITDARKLLPAVMRTLMHRDARLILCREFFGYVHGNKAVLDHQQFELVVRFMNKALQKSSGID
|.||.. .... . ... |||||||||| |.||||.|.|..|.|.||||.|.| ...|||.||.|.  .|..|.||||||||.||||.||||||..|  |
pagptvasivektkstvensarrlEvlrnCisyiFdnkileakKslpAvlralkskaaRlalceelekhvqqnravLdhqqFDlvvrlmNkaLqddsakd

EYTVAAALLPMSTIFCRKLSTGVVQFAYTEIQDHAIWKNLQFWESTFFQDVQGQIKALYLLhrRQNEHQKEANCVLDEVPLEEPTALEITAEQLRKSPNI
||.|||||||.|..||||||.||.||||| .||| .||| ||||.||.|.|| .||.|||   ...|..|....  ...  ||..||||.|.||||.|..
eygvaaallplssafcRKLsegvsqfaYtcvqdHpvWknqqFWeatfyqevqkaikelyle..kkseskkkkktesslskkeeksaleiaadqlrkwptl

EEEKKAELAKSEESTLYSQAIHFANRM
..||..||.|.||||.||||||||||.
skekqkelvkkeestvysqaihfanrl

DENN DENN (AEX-3) domain 142-324 8.4e-62 197.7 Pfam-A 1-184 (185) alignment
Range on Protein: 142-324
Range on HMM: 1-184/185.0
YAPKCLVLISRLDCAETFKNCLGTIYTVYIENLAYGLETLIGNILGCIQVPPAGGPQVRFSIGAGDKQSLQPPQSSSLPTTGSGVHFLFKQLGIKNVLIL
..||.|...|||.. |.||..| ...... ..    ||..| |.| ....|..| ... .| .. .|..|| |.||.||.... .. ||..|.|.||| |
ripkalcilsrlpffelfkkiLkalekrlksssklplesfianlllevplPapgktlklkslsvkekillqrpssselPledvdleelfrcLsienvlql

LCSVMTENKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHSSLQT-EITDLLDVIVVDLDG
...|..|..|..||. .. ||. ..|||||.||....|.|||.||| |..||..|||||.|..|||.. | ..| ||..|||| 
feavLlErriillSeklarLtsvaealvallyPlkWqhiyiPvlpaslldvleaPtPfiiGvesslleleekpledvvlvDldt

subfamily_MTMR1_pd Subfamily MTMR1 1376-1571 4e-56 183.0 In-house 146-335 (389) alignment
Range on Protein: 1376-1571
Range on HMM: 146-335/389.0
FCADFIPVDYPDIRQSRPAFKKLIRACMPShntneADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPY
  |..| .| ..|.  | ..|||  ...|.      | ... . .|.. ||..|..... . ..|. .. ...||..  .|| | |||| |.|.| ||.|
knaelifldihnihvvReslkklkelvlpn.....vddkkwlsalestkWlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsy

YRSLDGFRVLVEKEWLAFGHRFAHRSNLkPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGI
||...||.||.|||||.|||.|..|      . ...   .| ||||.| |.||.||||.|||||. .| .|. |. ||.| ||||..| || .. .
yRtieGfevliekeWlsfGHkfkeRlgh.gdknssdaersPvFlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekv

subfamily_MTMR3_pd Subfamily MTMR3 1378-1571 1.2e-52 172.1 In-house 205-392 (442) alignment
Range on Protein: 1378-1571
Range on HMM: 205-392/442.0
ADFIPVDYPDIRQSRPAFKKLIRACMpshntNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYR
.. . .. ..|   | .|..|   .      .  | . .   .|.  |||..| |.. .  ||. .| .. .|..   || | |.|. ..|.|.||||||
cevvflglanihavrksfnslralls.....qspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyr

SLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTNiAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGI
.|.||.||||.|||.|||.|| |.  ..   ..|   .| |||.||.||||||||| .||||. .|  |. |. || | |||...| ||... .
tleGfkvlvereWldfGhkfadrcghgenvddan.ercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekv

subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 1387-1571 1.6e-52 171.1 In-house 166-344 (404) alignment
Range on Protein: 1387-1571
Range on HMM: 166-344/404.0
DIRQSRPAFKKLIRACmpsHNTNEAdGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLV
.| . | ..|||  |.   ....|   . . . .|.| ||..|..|.. |  .|.||. ..|||..   || | |.||||..||.|||||| . || ||.
nihelreslkklkkav...nsiiek.eknwlselessrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivli

EKEWLAFGHRFAHRSNLkpSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGI
||||| ||| ||.|..   .. . .  ..| ||||.|.|.|| .|||  ||||. .|  . ... |||| |||.|.| ||... .
ekewlsfGhkfaqRigq..ttekssdersPiflqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnl

subfamily_MTMR9_pd Subfamily MTMR9 1394-1572 3.2e-48 156.7 In-house 168-342 (393) alignment
Range on Protein: 1394-1572
Range on HMM: 168-342/393.0
AFKKLIRACMpshnTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAF
.. ||. ||.     .. . ..|.. .|.| ||.|.  |....  |....| ....|..  |.| | | |..|.||| |||..| ..||  |.|.||.  
slaklleacs....daglstdkflsrleksgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqa

GHRFAHRSNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIA
|| ||.| .    . ...   .|.|| ||| |.|. .|||..||||. .| .|  || |..| ||| |.| ||.. .. 
GHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklk

subfamily_MTMR6_pd Subfamily MTMR6 1358-1572 3.7e-47 153.5 In-house 136-345 (397) alignment
Range on Protein: 1358-1572
Range on HMM: 136-345/397.0
RLYALGEKSQAKSNMNVDFCAD--FIPVDYPDIRQSRPAFKKLIRACmpshNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLE
.| || .|.. |   | |. ..  |  |.  .|   | . .||. ..    ...  . ..| . .|.|.||. | .... |  .   .  .. ||..   
klnalankaagkGyenednysnikfqfvgienihvmreslqkllevv....elksksvseflsglessgwlkhikavldasifiakavaeegasvlvhcs

DGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKpshANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRF
|| | |||  |.|.| ||||||...|| ||.|||||.|||.| .|. |     . .  ..| |.|||. | ||..|||.|||||. .|  |  |  ||.|
dGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGll...dedskevsPiftqflecvwqlleqfpkafefnerfllelhdhvyscqf

RTFLFDCELERSDSGIA
 ||| .|| .| |  ..
Gtflgncekdrrdlklk

subfamily_MTMR10_pd Subfamily MTMR10 1384-1569 1.3e-43 141.3 In-house 122-305 (380) alignment
Range on Protein: 1384-1569
Range on HMM: 122-305/380.0
DYPDIRQSRPAFKKLIRACMPSHNTN--EADgQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDG
. | |..   |..|| . |...  ..  ..| . .    |.. ||. .. .....  .|...  .. ||.|. ..|.|.   ..| |||.|||.||...|
elpsiqdvqkaylklreLcvidtseefvtld.dkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisG

FRVLVEKEWLAFGHRFAHRSNLKPSHAN-TNiafaPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDS
|  |..||| | || | .| .   .  .  .    |.|| |||.|.|| .||| .|||.. .|  |  .|.|. | ||||..| .|   
fqsliqkewvaaghpfldrlghikpsekses....pvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlka

subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 1379-1568 3.5e-37 120.1 In-house 163-351 (405) alignment
Range on Protein: 1379-1568
Range on HMM: 163-351/405.0
DFIPVDYPDIRQSRPAFKKLIRACMPS---HNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIdLQESSVMLSLEDGSDVTAQLSSIAQLCLDPY
 .. .. |.|   | ...||. |   |   ..  |.    |  ..|.. |. .| |... .    .|| |.  |...   || | | |..|..|. ||||
klvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwishiksileaatfsaeli.lkgnsilvhcsdgwdrtpqitsltqilldpy

YRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANtniAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSD
||.. ||.||.|||||.|||.|. |    |   .     .| | ||||.. ||  |||. |||    | |..    ||.. ||| .|| .| .
yrtivgfqvliekewlsfghkfslrlghlpgnee...erspifqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvq

uDENN uDENN domain 31-91 1.7e-21 65.4 Pfam-A 2-64 (65) alignment
Range on Protein: 31-91
Range on HMM: 2-64/65.0
GKIVQRFPEKDW-PDTPFIEGIEWFCQPLGWSLSYEK-QEPKFFVSVLTDIDANKHYCACLSF
.|| ..|||||. .|.|. . |..||.| |... ... |.|.||. ||||.| ...|..|| |
pkildqfPekdeeedeplpkaipmFCfPeglnfvtsreqkpeffsfvLTdedgsriyGfClrf

dDENN dDENN domain 383-452 1.4e-19 59.2 Pfam-A 1-68 (68) alignment
Range on Protein: 383-452
Range on HMM: 1-68/68.0
IDKELRAIFMRLFAQLLQGYRSCLTIIRIHPKpvITFHKAGFLGARDLIESEFLFRVLDSMFFTTFVNER
.|...|..|.|.||.||.|||..|...| .|.  ..|.|..|| .|.  ...|| ..|....|..|. ||
ldqqvreaFlrffasllggYrnflrkerkspe..vsFqkeaFlksrskshrsFlsqfletqmFaeFieer

subfamily_pats1_pd Subfamily pats1 1386-1508 2.4e-19 61.2 In-house 344-464 (691) alignment
Range on Protein: 1386-1508
Range on HMM: 344-464/691.0
PDIRQSRPAFKKLIRACMPSHNTNEAdgqsfAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQL---SSIAQLCLDPYYRSLDGF
|   . .  | .|... .   .....      | .|.| |.  .  |.. .  |  |.|  .| .. .  |. ... .|   ||.||. .||.||.||||
Ptrekveerffdllqsilsldgsdde.....wkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrtldGf

RVLVEKEWLAFGHRFAHRSNLKPSHA
.||.||||| .|. |....  | |. 
kvliekewlsyGfPfskinyhkesdd

GRAM GRAM domain 923-1001 5.4e-17 52.5 Pfam-A 2-68 (69) alignment
Range on Protein: 923-1001
Range on HMM: 2-68/69.0
KIQTPCLLPGEDLVTDHLRCFLMPDgredetqcLIPAEGALFLTNYRVIFKGSPCDPLFceqvIVRTFPIASLLKEKKI
|..... ||.|. . |...| |...        ..|..|.|.|||||.||.....|...    .|...|.|.. . .|.
kfrktfklppeEkllddyaCylsts........kgpvqGrlYlTnyrliFrSdklddsk....vvvvipladikrveks

PH PH domain 1892-1992 2.7e-15 46.8 Pfam-A 3-103 (104) alignment
Range on Protein: 1892-1992
Range on HMM: 3-103/104.0
HEGHLYKRGALLKGWKQRWFVLDSikHQLRYYDTSE---DTAPKGIIELAEVQSVTAAQPAQiGaKGVDEKGFFDLKTSKR-IYNFYAINANLAQEWIEK
.|| |.|.. ||| ||.|.||| |  ..| |.. |.   . ||||.| | ...  .| .. . | .  ...  | ... ..  | ..| ..  ...|...
keGyllkksellktwkkryfvLts..nyLlyfksskkksykapkgsiplndctvkkasstkf.g.aqkesnnyfeitfknvesyllsaeseeerkrWvqa

LQACL
|. .|
lknll

subfamily_MTMR3_pd Subfamily MTMR3 1155-1241 3.4e-15 48.7 In-house 22-107 (442) alignment
Range on Protein: 1155-1241
Range on HMM: 22-107/442.0
ERMRERSYVQDWKRLGFDaeSQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHA-NGALLIRGGQPN
... | .. .. .|||||   .  .|||..|...  |.|||  .. |.. .| .. .  .    .|.|   |||  |||.|.| .||.
asvaeeklkeeverlGfd..lkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPe

subfamily_pats1_pd Subfamily pats1 1510-1569 3.8e-15 47.3 In-house 548-607 (691) alignment
Range on Protein: 1510-1569
Range on HMM: 548-607/691.0
TNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDS
 | .|.| |.||||.| |||..||. ||||...|  |  .| | || .||..  ...|. 
vnrsfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdser

subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 1164-1241 3.7e-14 44.7 In-house 23-99 (404) alignment
Range on Protein: 1164-1241
Range on HMM: 23-99/404.0
QDWKRLGFDAESqrGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHA-NGALLIRGGQPN
...||||. .||   .|||..|. |  | .|| ..| | ..||  . .     . .|||  .|||  ... ..|  || 
eEykRlgikses..eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqpl

subfamily_MTMR9_pd Subfamily MTMR9 1167-1244 2.1e-12 38.8 In-house 29-100 (393) alignment
Range on Protein: 1167-1244
Range on HMM: 29-100/393.0
KrlgfdaeSQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRH-ANGALLIRGGQPNSKS
        .. ..|||. |  .. | |||. .. | . .| ..    .  .| |.|. ...| ...| |.| .|| . |
s.......asdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgs

C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) 1791-1839 4.9e-10 29.0 Pfam-A 1-51 (53) alignment
Range on Protein: 1791-1839
Range on HMM: 1-51/53.0
HRFEKHPYTTPTNCNHCTKLL--WGPVGYRCMDCGNSYHEKCTEHSMKNCT
|..... .  || |.|| |.|   | .|..| .|. ..|.|| |.  |.| 
HhwvhrnfkqptfCkhCgkflwgkgkqglkCswCqllvHkkCfekvpkecg

subfamily_MTMR1_pd Subfamily MTMR1 1164-1242 8.3e-10 30.5 In-house 14-91 (389) alignment
Range on Protein: 1164-1242
Range on HMM: 14-91/389.0
QDWKRLGFDAESqrGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHAN-GALLIRGGQPNS
.. .|||   |    .||.. |..|. | .|||..| | ..||  . . ..  . .|.|  .| . . .| ..|  ||..
aelerlgllnek..lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplv

PH_11 Pleckstrin homology domain 1893-1989 7.5e-09 25.7 Pfam-A 2-110 (112) alignment
Range on Protein: 1893-1989
Range on HMM: 2-110/112.0
EGHLYKRGAL-LKGWKQRWFVLDSiKHQLRYYDT-------------SEDTAPKGIIELAeVQSVTAAQPAQIGAKGVDEKGFFDLKTSKRIYNFYAINA
.| |.| |.  |||||.|||.|     .|.||.              ||.  .|. .. . ... . |....  | .   .  |  .. .. . ... | 
kGylkkkgskllkgWkrrwfiLrk.dnvleYyksprdksdvalitkesekvilkkdlsis.nrlskianikdkkalelshsnefsiaaeekslflkgdnn

NLAQEWIEKLQ
.  .||.|.|.
eeteeWvealk

subfamily_MTMR10_pd Subfamily MTMR10 1172-1240 8e-08 23.4 In-house 19-87 (380) alignment
Range on Protein: 1172-1240
Range on HMM: 19-87/380.0
DAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHANGALLIRGGQP
. ....... .. |   |.. ..|  .| | ..||  .  | | .|  | || .| ||.|| |.| .. 
kktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsal

PH_3 PH domain 1887-1990 8.2e-07 17.7 Pfam-A 10-97 (104) alignment
Range on Protein: 1887-1990
Range on HMM: 10-97/104.0
AENRTHEGHLYKRGALLkgWKQRWFVLDSIkHQLRYYDTSEDTApKGIIELAevqsvtaaqpAQIGAKGVDEKGFFdLKTSKRIYNFYAINANlAQEWIE
 |     | ..||  |.   ..|...| .   .| | | ....  || |.|            .. .. ...|.|| ..| ||.|...  ..| |..|..
gelilkqglvkKrkglf..arkRqlllteg.PrLiyvDpekmel.kGeIpls..........kelkvevknskkFf.ihtpkrtyyledpesn.aakWvk

KLQA
... 
aiee

PH_8 Pleckstrin homology domain 1898-1989 1.5e-06 17.9 Pfam-A 6-86 (89) alignment
Range on Protein: 1898-1989
Range on HMM: 6-86/89.0
KRGALLKGWKQRWFVLDSIKHQLRYYDTSEDTAPKGIIELAEVqsVTAAQPaqigakgvdEKGFFDLKTSKRIYNFYAINANLAQEWIEKLQ
||   |.|...|.||||  . .| || .....| .| | | .   . .|.          ||  . ...  ....  | |.. .|||.| |.
krrkklqgyakRfFvLdlksstlsYyrddnssalrgkiplsla..iisane.........ekreiiidsGaevWeLkasnekdfqeWveale