Gene CG3530 in Drosophila melanogaster

Synonym: BcDNA, BcDNA:GH04637, CG18093, Dmel\CG3530, Dmel_CG3530, CG3530

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR6
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP032_AA protein Get Run
DmelP032_AA_195-574 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR6_pd Subfamily MTMR6 179-571 9.6e-216 708.6 In-house 1-396 (397) alignment 
Range on Protein: 179-571
Range on HMM: 1-396/397.0
LYCFNYQPNKDDFPKNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLH-NNKASICRCSQP
||.|.|.|.||.. |..||....|.||...| ||||.|||...|..|||||||||..||||.||. .|..||.||||||||||.||| .|.|.|||||||
lyafsykpkkdkeekvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqp

LSGFSARCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSG
||||||||||||..||||||.|.|....|||||||..||.||.|||||||||..|.||||.|.|||||||.|.||||.||..|.||...|.|...|||||
lsgfsarcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsglessg

WLKHIRSILDTSSFIANAV-DKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREVSPIFTQFLDCTWQ
|||||...||.| |||.|| ..|.||.|||||||||||||||||.|.|.|||||||||. ||||.||.||||||||||....|..||||||||||.|.||
wlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvwq

LMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVD-EAIKANLAPQCIKFWRGMYSRFE
|..|...|||||||||| |||||.|||||||.||||||| ||||.|||.|||.|.... ..|.|||||.. . |..|...||...|.||..|.||.
lleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwralynrfd
0040695 (Phosphotyrosine protein) phosphatases II 194-570 6.7e-146 479.7 In-house 5-385 (388) alignment 
Range on Protein: 194-570
Range on HMM: 5-385/388.0
NAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN-NKASICRCSQPLSGFS-ARCLEDEQM
  || ..  . |.|.. .... | ... ||.||||..||....|||...  .|....|||||||.|||.| |  |.|...|.||||.|..  |.||||..
eegwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledekl

LEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACeQKSPTMSAFINALESSGWLKHIRSILDTSSF
||||.|...|......||.||..||.||||.|.|.||| .| |....||.|.|||| |.||||.|.||  ..|... ....||.||||..|..||... .
leailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldac.lnvpdslnllslleesgwldliklilelavl

IANAVDKGVS-VVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQT--DAREVSPIFTQFLDCTWQLMSQRSEAFEFN
|.. .|.| | |.||||||||||.|..|||||.|.|||||..||| ||||.||.|||||..|.||     |  |.||.| .||||.|||. |   |||||
ivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFn

ERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMYSRF
||.|| |.||..||.||||..|.||.||.|.. |||.||| |.  . .|..||||.|. .| .. .| ......| ..| |.
erlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpsslevllpslsvldlllWleyylrw
Myotub-related Myotubularin-like phosphatase domain 178-517 4.3e-142 466.0 Pfam-A 1-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 178-517 4.3e-142 466.0 In-house 1-352 (353) alignment
subfamily_MTMR1_pd Subfamily MTMR1 194-571 4.3e-140 459.4 In-house 4-387 (389) alignment 
Range on Protein: 194-571
Range on HMM: 4-387/389.0
NAGWDYFKLEAEFKHMLVPNE-AWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHNN-KASICRCSQPLSGFSA-RCLEDEQ
. ||. .. |||.. . ..|| .|  ...|.|||||||||. ..||| ..  .|  ...||||||||||..|... .|.| |.||||.| |. |. |||.
edGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedek

MLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSpTMSAFINALESSGWLKHIRSILDTSS
.|.||...|.... ....| |...||.||.| |||||.|..|.|... || |.|||| |.||.|. |..  .    . ...||||. ||.||..||... 
ylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnv.ddkkwlsalestkWlehiklilagav

FIANAVDKG-VSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGH--IQTDAREVSPIFTQFLDCTWQLMSQRSEAFEF
 |...|..   ||.||||||||||||. |||.|.|..|||||.||. ||||.||.|||||.|| ||   ..  .| ||.| ||.|| |||. |   ||||
kivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFef

NERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNV-DEAIKANLAPQCIKFWRGMYSRFE
||.||..| ||..|| ||||. |.|| | . |. |.| ||| |. .. .|..||||.... .... .... .... |.  | |..
neefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyylrwn
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 180-570 3.3e-130 426.9 In-house 1-402 (404) alignment 
Range on Protein: 180-570
Range on HMM: 1-402/404.0
YCFNYQPNKDDFPknAGWDYFKLEAEFKHMLVPNE-AWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN-NKASICRCSQP
..|.|...|       ||  .. | |.| . ...|  | . ..| .||||.|||... ||.. .   | ... ||||||.|||.. |. ....| |.|||
fafsysekksvle..dgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqp

LSGFS-ARCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESS
| | . .|. |||.....|||...... .|..|.||..||.||.| |.|||.   ||| . .||.|||||  | ||.|. .|...     . ... ||||
lvGltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlseless

GWLKHIRSILDTSSFIANAVD-KGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGH-IQTDAREVSPIFTQFLDCT
.|| ||...| .|  |.. .. .. ||.||||||||||.|..||.||.|.||||||.||. ||||.|| ||||| .|.|.  ...  | |||| ||.|| 
rWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcv

WQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANL--------APQCIKFWRGM
.||. |  . |||||.||. . |.. ||.||||. ..||.| . .||. | ||| .. .. .||.||||  .  |  ..           .. ||.|. .
yqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWsey

YSRF
| |.
ylrw
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 212-571 4.9e-109 356.8 In-house 38-405 (405) alignment 
Range on Protein: 212-571
Range on HMM: 38-405/405.0
PNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLH-NNKASICRCSQPLSGFS-ARCLEDEQMLEAIRKtNSNTDYMYVVD
 |  | . |.| .|..| .|.  . | . |.   |     ||||||.| |..   . .||| |||||| |   ||| |||    ..    . .  .|..|
sncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarcpedelycsslal.sapsktlylid

TRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACE----QKSPTMS---AFINALESSGWLKHIRSILDTSSFIANAVDKGVSV
.||..||.|| | | |.||   | | |. |. | |||| | ||.|.  | .    .|  | |    |   .| .||. ||.|||....| |. . || |.
arpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwishiksileaatfsaelilkgnsi

VVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSC
.|||||||||| |. ||.|..|.||||||.||| ||||.||.|||||| | ||.  .  | |||| ||||| .||.||    |||   .||.. | .|||
lvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfqllsqfpllfeftpslllfisdnihsc

QFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMYSRFE
..|||. ||||||.. ..  .| |.|  .   .| ..|| |.|.  ..|| .|  .|...|.  | |.|
kygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqsikpklysrclelwkacymrve
subfamily_MTMR9_pd Subfamily MTMR9 193-570 3e-107 351.1 In-house 11-392 (393) alignment 
Range on Protein: 193-570
Range on HMM: 11-392/393.0
KNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLH-NNKASICRCSQPLSGFS-ARCLEDEQ
.. |.. |. | ||... .. ..| . |.|.....| .|| .. |||  .   |  |..||..||.|||.||| ..|| . |.||||.| |  || |||.
ledgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedek

MLEAIRKTNsntDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSS
.|... |..      ..||||    |...|. | | | |. | ..| .   .|....   ||.|.||||.... ... |.. ||.||||.... .|... 
llnlvlkkl...kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadlleaal

FIANAVDK-GVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTD---AREVSPIFTQFLDCTWQLMSQRSEAFE
 .|...|. |..|||| ..| | | || |||||.|.|..||..||.||||..|.  || |..|. ..      ... .|.|  |||| .|..||   .||
vvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFE

FNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMAN--HLNEYINPLYKPNvDEAIKANLAPQCIKFWRGMYSRF
|||..| .|. | .|.|||||....|. | .||| ..| ||| |. .  .|....||||..| .| | .. |||....|...| |.
FneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyean.aeviwpsvapqslelWselylrw
subfamily_MTMR3_pd Subfamily MTMR3 299-568 2.9e-89 292.9 In-house 169-440 (442) alignment 
Range on Protein: 299-568
Range on HMM: 169-440/442.0
NSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEqKSPTMSAFINALESSGWLKHIRSILDTSSFIANAVDK
 ...  . .|| |    |.|||| | |.|.| .|.| .  |||. |||  | |.... . .. .||  | .. |||.  ||...  .| ..  ...||||
aeekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslralls.qspdesnwlsalektkWlqnlsvllkaavkvveavdk

-GVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQ--TDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLIL
 | .|.||||||||||.|. .||.|.|.|||||..||..|.|..||.|||||..|||| .   || | .|.| |.||.  ||  |   .||||| ||. |
egrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvkl

HDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMYS
  | .|| ||||..|.||.| . |. |||.|.| .. .. .|| | |||.. .  . ..   . .|.|. .| 
vqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekteavllpavsvrelklwsevyl
subfamily_MTMR5_pd Subfamily MTMR5 312-563 4.8e-61 199.0 In-house 206-475 (483) alignment 
Range on Protein: 312-563
Range on HMM: 206-475/483.0
PRINAMANRAAGKGYENEaFYENIKFHFLGIENIHVQRASLQKVLEACEQK----SPTMSAFINALESSGWLKHIRSILDTSSFIANAVD-KGVSVVVHC
 .. .. ...  |... | .. .. |  . . .|   .||..|.| ||  .    ......|....| | ||. |.|.|. |. ... .| .| ||.|  
aaLYvlgeksqlknvkse.vdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvsl

SDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAR-EVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFG
 |||| |||| |||||.|.|||||..||..|.||.||||||.|..|. .... .   ..|.| ||||| .|...|   |||||. .| .|  |  |..| 
EdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfr

TFVGNCEKDRLDLKL----------AERTFSLWGYMANHLN---EYINPLYKPNVDEAIKANLAPQCIKFW
||. ..|..||.  |           . . |.| |. .. .    . | ||.|. .|... .     .| |
tfllDseyerlesgllyeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvW
subfamily_MTMR10_pd Subfamily MTMR10 354-522 4e-51 166.0 In-house 135-309 (380) alignment 
Range on Protein: 354-522
Range on HMM: 135-309/380.0
KVLEACEQKSPT-----MSAFINALESSGWLKHIRSILDTSSFIANAV-DKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGH
|. | |   ...        .. .||...||. .| .| |.| ....| .|. ||..  |.| |    |.||||||| |.||||.||| ||.| | | ||
klreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaagh

KFSERCGHIQTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAE
.| .|.|||. .  . ||.|  ||||..||. | ...|||.|.||. |.|..||. |.||. |.|. ||  .   
pfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvss
subfamily_pats1_pd Subfamily pats1 337-459 2.8e-22 70.9 In-house 338-463 (691) alignment 
Range on Protein: 337-459
Range on HMM: 338-463/691.0
FHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINaLESSGWLKHIRSILDTSSFIANAVDKGVSVVVH-CSDGWDRTAQV---CSLAQLMLNPYYRTIK
  || .   .  ..   ..|..  .   ..... . .| | |.  .. .|...  ..| .|.| ||...  .|. . . ..    ||||....|.|||. 
iiflslPtrekveerffdllqsilsldgsddewke.ieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrtld

GFQALIEKDWLAFGHKFSERCGHIQTD
||. ||||.|| .|. ||... | . |
GfkvliekewlsyGfPfskinyhkesd
subfamily_MTMR3_pd Subfamily MTMR3 203-300 3.7e-22 71.7 In-house 30-130 (442) alignment 
Range on Protein: 203-300
Range on HMM: 30-130/442.0
EAEFKHML-VPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN-NKASICRCSQPLSGF-SARCLEDEQMLEAIRKTN
..|.. .    .||| . ..|....|| .||... |||. |  .| ....||| .|||.. . |. |.| . |||||  |. . |. |||..|.|| |. 
keeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiakac

S
.
a
subfamily_pats1_pd Subfamily pats1 461-546 1.8e-20 64.9 In-house 550-635 (691) alignment 
Range on Protein: 461-546
Range on HMM: 550-635/691.0
REVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPN
|  |||| ||||  |||  .    ||||| .||.| ....| .||.|. .  |.. . |. .|. |.| ..      .|| |||. 
rsfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhs
FYVE FYVE zinc finger 694-757 6.3e-15 44.9 Pfam-A 2-68 (69) alignment 
Range on Protein: 694-757
Range on HMM: 2-68/69.0
DWKPMRNVTTCS-CSTPFDQFSKKTHCWRCGDIFCERCIDKNVALP--GHDSGKPVPVCRGCFRQMQ
 |.. .....|. |...|  .... ||  ||...|..|..|.|. .   ....|.| ||. |.....
kwvddaeakkCeiCakkFsltrrrhhCrlCGkvvCskCsskrvekleeesaeekevrvCkeCleels
PTPc_DSPc_SM00012 337-498 4.1e-14 48.0 In-house 5-103 (105) alignment 
Range on Protein: 337-498
Range on HMM: 5-103/105.0
FHFLGIENIHVQR--ASLQKVLEACEQKSPTMSAfinalessgwlkhirsildtssfianavdkGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTikgf
.|..|. . .| .   |. ..|.|....    .                               . .||||||.|..||.... |. |. . ...|    
yhytgwpdhgvPeesdsilellravkknknkses..............................skpvvVhCsaGvgRtgtfvaldillqqleket....

qaliekdwlafghkfsercghiqtdarevspIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDH
                                . ..... ..|..||. .....| .| ... .
...............................kevdifqivkelrkqRpgmvqteeqylflyral
subfamily_MTMR5_pd Subfamily MTMR5 213-280 3.7e-10 31.2 In-house 28-96 (483) alignment 
Range on Protein: 213-280
Range on HMM: 28-96/483.0
NEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN-NKASICRCSQPLSG
.. . . ..|.||..|..||  | ||.|     .   ..   ..|||| |. |. ||| . | ... | 
rgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfesk
subfamily_MTMR10_pd Subfamily MTMR10 210-314 6.2e-09 27.1 In-house 20-123 (380) alignment 
Range on Protein: 210-314
Range on HMM: 20-123/380.0
LVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHNNKASICRCSQPLSGFSARCLEDEQMLEAIRKTNSNTDYMyVVD
 . ..|.     ||. . . |.|....||.  .   .   ||   ..| |.... | . |.  |.|.     ||   . |.||| .||.... |   .||
ktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsalqeaesadkekeekmlelvrkchpandvk.lvd

TRPRI
.  ..
lsdel
0049772 (Phosphotyrosine protein) phosphatases II 285-424 1e-08 30.8 In-house 156-237 (314) alignment 
Range on Protein: 285-424
Range on HMM: 156-237/314.0
CLEDEQMLEAIRktnsntdymyvvdtrprinamanraaGKGYENEAFYEN-IKFHFLGIENiHVQRaSLQKvleaceqksptmsafinalessgwlkhir
.. ... || ..                          .  |..| | .. ||.. . ..  . .  .|.                              
neptaadlellk..........................eelydpelferlgikylripvpD.gsap.lled.............................

sILDTSSFIANAvDKGVSVVVHCSDGWDRTAQVCSLAQLML
 ...   || .| |||  |.|||..|..||.  . .| ||.
.fdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmk
0045098 (Phosphotyrosine protein) phosphatases II 380-449 1.9e-08 29.6 In-house 171-267 (278) alignment 
Range on Protein: 380-449
Range on HMM: 171-267/278.0
KHI--RSILDTSSFIANAVD--------------KGVSVVVHCSDGWDRTAQVCSLAQLMLN-----------PYYRTIKGFQALIEKDWLAFGHKF
 .   .|.|.   || .|..              .|  |.|||| |..||. .. .  .. .            ..|. ....|.  .... | ..|
slpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyef
0051429 (Phosphotyrosine protein) phosphatases II 332-432 1.4e-07 27.0 In-house 67-183 (272) alignment 
Range on Protein: 332-432
Range on HMM: 67-183/272.0
YENIKFHFLGIENIHVQRASLQK-----------------VLEACEQKSPTMSAFINALESSGWLKHIRS---ILDTSSFIANavdkGVSVVVHCSDGWD
 ..|....| |.. .... .. .                 .|..  . |....  .  |   .|. |      .|.  .....    |  |.|||| |.|
wpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld....ggpvlvHCsaGkd

RTAQVCSLAQLMLNPYYRTIK
||. |. |  |.|.  . || 
RTGtvvallllllgvsletiv
0048076 (Phosphotyrosine protein) phosphatases II 380-424 3.7e-07 25.5 In-house 62-105 (145) alignment 
Range on Protein: 380-424
Range on HMM: 62-105/145.0
KHIRSILDTSSFIANAVDKGVSVVVHCSDGWDRTAQVCSLAqLML
  .. .|.   || .|...|  |.|||| | .||. .. .  |||
dllellleflefieealkeggpvlVHCsaGvgRtgtlvaay.lml
0048179 (Phosphotyrosine protein) phosphatases II 378-423 3.9e-07 25.4 In-house 62-107 (144) alignment 
Range on Protein: 378-423
Range on HMM: 62-107/144.0
WLKHIRSILDTSSFIANAVDKGVSVVVHCSDGWDRTAQVCSLAQLM
   ..  .|..  || .|...|  |.|||| | .||. .. .  ..
vpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk
0043147 (Phosphotyrosine protein) phosphatases II 381-423 1e-06 24.1 In-house 80-124 (172) alignment 
Range on Protein: 381-423
Range on HMM: 80-124/172.0
HIRSILDTSSFIAN--AVDKGVSVVVHCSDGWDRTAQVCSLAQLM
... .|.. .|| .  |...|  |.|||| |..||. .. .  ..
llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml
0051082 (Phosphotyrosine protein) phosphatases II 334-425 1.1e-06 23.9 In-house 57-118 (151) alignment 
Range on Protein: 334-425
Range on HMM: 57-118/151.0
NIKFHFLGIENIHVQRaslqkvleaceqksptmsafinalessgwlkH---IRSILDTSSFIANavDKGVSVVVHCSDGWDRTAQVCSLAQLMLN
.|... . |.. ...                                    . ..|.  .....  .|.  |.|||| |..||. .. |  ..|.
gievlhipildwpdpg...............................lplsfdavleflellld..kkngpvlvHCsaGkgRTGtlvalylmllg
0046846 (Phosphotyrosine protein) phosphatases II 383-424 1.3e-06 23.8 In-house 93-134 (176) alignment 
Range on Protein: 383-424
Range on HMM: 93-134/176.0
RSILDTSSFIANAVDKGVSVVVHCSDGWDRTAQVCSLAQLML
. .|.   || .|...|  |.|||| |  ||. .. .  |.|
elllellefirealkeggpvlVHCsaGigRtgtlvaayllel
subfamily_MTMR14_pd Subfamily MTMR14 398-454 1.7e-06 19.1 In-house 267-329 (357) alignment 
Range on Protein: 398-454
Range on HMM: 267-329/357.0
KGVSVVVHCSDGWDRTAQVCSLAQLMLNPYY---RTIKGFQAL---IEKDWLAFGHKFSERCG
.   ..|||  |||||    || .| |       ....  . |   .  ||. |||....|  
edsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrlk
0037934 (Phosphotyrosine protein) phosphatases II 388-426 2e-06 23.0 In-house 158-205 (243) alignment 
Range on Protein: 388-426
Range on HMM: 158-205/243.0
T----SSFIAN-----AVDKGVSVVVHCSDGWDRTAQVCSLAQLMLNP
      .|| .     | |.|  |.|||| | .||. .. .  ..|. 
fldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll
0044763 (Phosphotyrosine protein) phosphatases II 382-421 2.2e-06 23.0 In-house 92-132 (178) alignment 
Range on Protein: 382-421
Range on HMM: 92-132/178.0
IRSILDTSSFIANAV-DKGVSVVVHCSDGWDRTAQVCSLAQ
.. .|..  || .|. .||  |.|||| |..|.. .. .  
lehflefvefieealdekggpvlVHCsaGvgRsgtlvaayl
0042113 (Phosphotyrosine protein) phosphatases II 381-422 3.4e-06 22.2 In-house 156-199 (245) alignment 
Range on Protein: 381-422
Range on HMM: 156-199/245.0
HIRSILDTSSFIANAVD--KGVSVVVHCSDGWDRTAQVCSLAQL
.....||  .|. .|.   ..  |.||||.| .||. .. .  .
llellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylm
subfamily_pats1_pd Subfamily pats1 197-278 3.5e-06 17.7 In-house 6-90 (691) alignment 
Range on Protein: 197-278
Range on HMM: 6-90/691.0
WDYFKLEAEFKHMLVPNEA-WTLCSMNeKYELCDTYPRQIYVPKEATTLMLISSSRFRSKgRLPVLTYLHNNK-AS---ICRCSQPL
.| . |  |.. . .  .  |    .  . .|.. ||..| |||  .  .| |. | ||  ..|||.. ..|. .|   ||   ||.
fdiyslliegqrlkldldkdwrvvefl.srdlseiyPkrilvPklvsdellvsyvrkrss.kiPvlswsnqnnksslfricvynqpf
subfamily_MKPLT_pd Subfamily MKPLT 386-432 5.1e-06 20.1 In-house 85-130 (164) alignment 
Range on Protein: 386-432
Range on HMM: 85-130/164.0
LD-TSSFIANAVDKGVSVVVHCSDGWDRTAqVCSLAQLMLNPYYrTIK
|. .. |.|.|.| |  |.|||  |  |..  ...| |..   . |.|
leraakfladaidsGGrvlvhcvqGksrss.svtvafLikskgw.tlk
subfamily_MKPLV_pd Subfamily MKPLV 386-432 5.1e-06 20.1 In-house 85-130 (164) alignment 
Range on Protein: 386-432
Range on HMM: 85-130/164.0
LD-TSSFIANAVDKGVSVVVHCSDGWDRTAqVCSLAQLMLNPYYrTIK
|. .. |.|.|.| |  |.|||  |  |..  ...| |..   . |.|
leraakfladaidsGGrvlvhcvqGksrss.svtvafLikskgw.tlk
0039614 (Phosphotyrosine protein) phosphatases II 381-422 6.1e-06 21.4 In-house 201-245 (297) alignment 
Range on Protein: 381-422
Range on HMM: 201-245/297.0
HIRSILDTSSFIANAVD---KGVSVVVHCSDGWDRTAQVCSLAQL
.....|.   .. .|.    ||  |.||||.| .||. .. .  .
slellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylm
0036282 (Phosphotyrosine protein) phosphatases II 385-427 7.4e-06 21.3 In-house 88-132 (174) alignment 
Range on Protein: 385-427
Range on HMM: 88-132/174.0
ILDTSSFIANAVDK--GVSVVVHCSDGWDRTAQVCSLAQLMLNPY
.|.  .|. .|. .  |  |.|||| | .||. .. .  .. . .
llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll
0040439 (Phosphotyrosine protein) phosphatases II 386-422 8.2e-06 21.1 In-house 160-202 (249) alignment 
Range on Protein: 386-422
Range on HMM: 160-202/249.0
LDTSSFIANAV------DKGVSVVVHCSDGWDRTAQVCSLAQL
 |. .||  .       .||  |.||||.| .||. .. .  .
edlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
0041856 (Phosphotyrosine protein) phosphatases II 386-420 8.9e-06 20.9 In-house 96-130 (182) alignment 
Range on Protein: 386-420
Range on HMM: 96-130/182.0
LDTSSFIANAVDKGVSVVVHCSDGWDRTAQVCSLA
 .. .||  . ..|  |.|||| | .||. .. . 
delldfieevleeggpvlVHCsaGvgRtgtlvaay