Synonym: CG1228, Dmel\CG1228, MEG1, Meg, PTP-meg, anon-WO0118547.211, dMEG1, dPtpmeg, ptmpeg, ptpmeg, scc, Dmel_CG1228, Ptpmeg
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPN3_pd | Subfamily PTPN3 | 627-962 | 8.5e-143 | 469.3 | In-house | 2-278 (280) | alignment | ||
Range on Protein: 627-962
Range on HMM: 2-278/280.0
TQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTgDYINANYVNMEIPG-GAVNRYIATQGPLASTTTDF
..|||||..||.|||.|||.| .|||.|.|||..||||.|..|||||||.|||.|||.|..| | |||||||||||||. |.||||||||||||.|.|||
resllllkeglesGavlaqfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset.dyinanyvnmeipstglvnryiatqGPlaktatdf
WRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAeGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFT
|.||....|.|.|||||..|.||.||||||| |..||... .|||.| .| ||| |.|.||.|||||. |.|.|...||||||||.||.|.. ||||.
WqmvweqksslivmlttlverGrvkChqyWPetedeleyg.efsvkceke..detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefv
ERVRAARnrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEARE
||||..| |... ||.|||||||||||||||..|||||.||.|
ervrklr..........................................................sgkeePvvvhCsaGigrtGvlilletalalieaae
PVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKI
||||||||||||||||..||..|||.||||.|...|..|
pvypldivrtmrdqramlvqtasqykfvCeailkvyeei
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 630-961 | 6.9e-86 | 283.7 | In-house | 32-301 (308) | alignment | ||
Range on Protein: 630-961
Range on HMM: 32-301/308.0
LLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLvnSLTGDYINANYVNMEIpGGAVNRYIATQGPLASTTTDFWRMV
| || . | .| | ...| .... |.| .. |..|.| .||||.|| ||| .|| | . . |||||.||.. . . ...||||||| .|. ||||||
lkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl..degsdYInAsyvdgys.sklprkfIatqgPlpntvedFwrmv
QQESSHLLVMLTTVMESGRQKCHQYWPVTGE-ELQLAEGFSVRCLSEKPdeTGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERV
.. ... ||||. .| ||.||.|||| . . . . ..|.|..|||. .... |.. |.. . | |...|..|..||||.||..|. .|.| |.|
weqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev..lddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelv
RaarnrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhQCIsaANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVY
| ... ..|..||||||.||||..|..|..| ..|. |
r..........................................................ksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvd
PLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
....|...| ||..|||...||.|...... ...
vfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 641-958 | 1.8e-82 | 272.3 | In-house | 24-285 (288) | alignment | ||
Range on Protein: 641-958
Range on HMM: 24-285/288.0
ALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSL---TGDYINANYVNMeipGGAVNRYIATQGPLASTTTDFWRMVQQESSHLL
||...| .....||| .. |..|.| .||||.|| ||| .|| | . ..|||||.|... ...||||||| .|. |||||| .. ...
glleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidg...ynlkrkfIatqgPlpntvedFWrmvweqnvrvI
VMLTTVMESGRQKCHQYWPVtgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLK------DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRaarn
||||...| ||.||.|||| .. . . ..|..|||. .... |.. .. ..| |...|..|..||||.||..|.|.|.| ..||
vmltklvelgrekcaqYwpl..ggsltygditvtllseev..lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvr....
rtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIV
..... ..||.||||||.||||..|..|..| ..|... | .|..|
......................................................kalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleav
RTMRDQRACMVQNVSQYRFVCECICAA
...| || .|||...|||||.|... .
krlreqRpgmvqtpeqyrfvyealley
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 633-961 | 2.1e-82 | 272.0 | In-house | 6-279 (297) | alignment | ||
Range on Protein: 633-961
Range on HMM: 6-279/297.0
LSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLvNSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQE
| . | . || ..| ... .. .. |..|.| .||||.|| ||| ||| | .. |||||.||.. . ...||||||| .|. |||||| ..
lekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl.ddegsdYinAsyvdgy...dlkrkfIatqgPlpntvedFWrmvweq
SSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
.. .||||...| ||.||.|||| . .| . ..|.|..||.. .. .... |.. ..| . |.|...|..|. ||||.||..|. .|.| |.|| ..
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvl
NRTllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisAANPPVIVHCSAGIGRTGVLILMDTALALME---AREPVYP
. . ..||.||||||.||.|..|..|..| ..| .. | .
kll........................................................psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdi
LDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
|..|...|.||...||...||||..|.. ..|
leavkklReqRpgavqtleqyrflyeallellkk
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 632-956 | 5.2e-81 | 267.4 | In-house | 4-269 (273) | alignment | ||
Range on Protein: 632-956
Range on HMM: 4-269/273.0
LLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLvNSLTGDYINANYVNMeipGGAVNRYIATQGPLASTTTDFWRMVQQ
|| . | .. ||...||... |.| .. |..|.| ||||.|| ||| .|| | .. . |||||.||.. ...||||||| .|. |||||| .
llekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl.gdggsdyinAsyvdg...ynlkrkfiatqgPlpntvedfwrmvwe
ESSHLLVMLTTVMESGRQKCHQYWPVTGEE-LQLAEGFSVRCLSEKPdeTGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
. ....||||...| ||.||.|||| .|.| . . |.|..|||. .... |.. |.. .| |...|..|. ||||.||.... .||| | ||
qnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet..kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrk
ARNrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPL
|.. . |.||.||||||.||||..|..|..| ..|.. | .|
ale........................................................alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvl
DIVRTMRDQRACMVQNVSQYRFVCECIC
..|. .|.|| .|||...||||..|...
eavkllrsqRpgmvqtpeqyrflyeall
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 640-961 | 2.1e-80 | 265.6 | In-house | 18-278 (317) | alignment | ||
Range on Protein: 640-961
Range on HMM: 18-278/317.0
GALLAQYELMYRKNPDlAITEARKPANAPKNRYRDISPYDCTRVSLVNSLT---GDYINANYVNMeipGGAVNRYIATQGPLASTTTDFWRMVQQESSHL
.||| ..| ... ..| ...|..|.| .||||.|| ||| .|| | . |||||.||.. ...||||||| .|. ||||||... ...
talleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdg...pnlkrkfIatqgPlpntvedFwrmvweqgvtv
LVMLTTVMESGRQKCHQYWPVtgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARnrtl
.||||. .| ||.||.|||| .| . ..|.|..|||. .... |.. ..| . |.|...|..|..||||.||..|.|.|.| |.||.|.
ivmLteleelgrekcaqYwpl..getltygdftvtllseee..lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreal....
lqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTM
. . ||.||||||.||||..|.....| ..| .. | . ..|...
......................................................edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkel
RDQRACMVQNVSQYRFVCECICAAYMK
| ||...||. .||||...... ...
reqRpgavqtpeqyrflydalleylkr
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 642-961 | 2.2e-80 | 265.4 | In-house | 2-276 (284) | alignment | ||
Range on Protein: 642-961
Range on HMM: 2-276/284.0
LLAQYELMYRKNPDL--AITEARKPANAPKNRYRDISPYDCTRVSLVNSLT----GDYINANYVNMEIPG--GAVNRYIATQGPLASTTTDFWRMVQQES
| ...| ... ...| .. |..|.| ||||.|| ||| .|| | . .|||||.||.. . ...||||||| .|. |||||| ..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
SHLLVMLTTVMESGRQKCHQYWPVTgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLKD---KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
....||||. .| ||.||.|||| . .| . ..|.|..|||. .... |.. |.. . | |...|..|..||||.||..|. .||| . || ..
vrvIVmltelvengrekcaqYwple.gevltygdftvtllseev..kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrell
NRTLLQeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisaanPPVIVHCSAGIGRTGVLILMDTALALMEARE---PVYP
... . .|..||||||.||||..|..|..| ..|... | .
enlpgg........................................................gpivVHCsaGvgRtGtfialdllleqlekeglllgvdv
LDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
|..|. .|.|| .|||...|||||.|... ....
leavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 636-958 | 2e-79 | 262.4 | In-house | 28-288 (297) | alignment | ||
Range on Protein: 636-958
Range on HMM: 28-288/297.0
GLASGALLAQYELMYRKNPDlaITEARKPANAPKNRYRDISPYDCTRVSLVNS----LTGDYINANYVnmEIPGGAVNRYIATQGPLASTTTDFWRMVQQ
. .. ||...| ... .|| ...|..|.| .||||.|| ||| .|| | | |||||.|| . . ...||||||| .|. ||||||..
ansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyv..dgydlltrkfIatqgPlpetvedFwrmvwe
ESSHLLVMLTTVMESGRqKCHQYWPVTGEelqLAEGFSVRCLSEKPdeTGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
. .. .||||. .| || ||.|||| .|. ..|.|..|... . .. |.. .... | |...|.||. ||||.||....|.||| | || |..
qgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh..ldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvreala
RtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIV
. . . ||.||||||.||||..|.....| ..| . | .|..|
e........................................................lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleav
RTMRDQRACMVQNVSQYRFVCECICAA
...| || ..||. |||||......
kelreqRpgavqtpsqyrflydallel
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 641-957 | 7.4e-78 | 257.7 | In-house | 28-302 (307) | alignment | ||
Range on Protein: 641-957
Range on HMM: 28-302/307.0
ALLAQYELMYRKNP--DLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLT----GDYINANYVNMEIP-----GGAVNRYIATQGPLASTTTDFWRMV
||...| ... .. ...|..|.| .||||.|| ||| ||| | . .|||||.||.. .. ...||||||| .| |||||.
gllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrml
QQESSHLLVMLTTVMESGRQKCHQYWPVTgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLK---DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERV
... ....||||. .| ||.||.|||| . .| . . | |..|||. .... | . .. ..| |...|..|..||||.||.... .|.| |.|
weqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh..ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev
RAARNRtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREP--
|.|... . . ||.||||||.||||..|.....| ..|...
rkalee........................................................lpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtll
-VYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
| .|..|...|.|| ..||| .||||..|...
dvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 640-956 | 2.7e-76 | 252.0 | In-house | 20-274 (278) | alignment | ||
Range on Protein: 640-956
Range on HMM: 20-274/278.0
GALLAQYELMYRKNPdLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMeipGGAVNRYIATQGPLASTTTDFWRMVQQESSHL
.||...| ... .. .. |..|.| .||||.|| ||| .|| | . | |||||.||.. ...||||||| .|. ||||||... ..
tllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdg...ynvprkfiatqgPlpetvedFwrmvwelgvtt
LVMLTTVMESGRQKCHQYWPvtgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARnrtl
.||||. .| ||.||.|||| .. . ..|.|..|.|. . .. | . .. ..| |...|..||.||||.||....|.|.| ..|| |.
ivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh..lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreal....
lqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTM
. | ||.||||||.||||..|.....| ..| . | ....|...
......................................................edsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkel
RDQRACMVQNVSQYRFVCECIC
| ||...||. |||||..|...
reqRpgavqtpsqyrflyeall
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 642-959 | 5.5e-75 | 247.6 | In-house | 9-272 (278) | alignment | ||
Range on Protein: 642-959
Range on HMM: 9-272/278.0
LLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSlvnsltgDYINANYVNMEiPggavNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
|| ..| .. .. ||.| .. |..||||.|| ||| .|| |||||.|... | ...||||||| ||. |||||.... .. .||||
lllefefllllgipseitpalylgnldknRykdilpydhsrVk.......dYINAsyidgy.p....kkfIatqgPlpstvadfwrmlwelgitvivmlt
TVMESGRQKCHQYWPvTgEELQLAEGFSVRCLSEKPDetGSFVFREFVLK------DKHEQRHIHHMQYLAWPDHCVPSDP--NLFLEFTERVRAARNRT
...| ||.||.|||| .. . ..|.|..|||. . .. | . . |.|...|..|| ||||.|||.| . |||..|..|.|...
elvelgrekcaqywp.e.ggsltygdftvtllseevl..ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkll
LLQEIEESlkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqCISAANPPVIVHCSAGIGRTGVLILMDTALALMeaREPVYPLDIVRT
. . . . . . ||.||||||.||||.|..... | |. . | .|..|..
aslllssl.............................................llldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavke
MRDQRAC-MVQNVSQYRFVCECICAAY
.| || . .||| .||||..|... .
lrsqRpglavqnleqyrflyefllell
|
|||||||||
DSPc_SM00195 | 644-959 | 1.2e-74 | 246.3 | In-house | 4-262 (263) | alignment | |||
Range on Protein: 644-959
Range on HMM: 4-262/263.0
AQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSL---TGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVML
...| . ..... .|||.|..| ||||..| ||| ||| | .. . |||||||.... ..|||||||| || |||||| .| ... |||
eefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga...nkkkkyIatQgPlpstvedFWrmvweekvkiivml
TTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDEtGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTllqei
| .|.|..||..||| . .. . . .|| . ... .. ... |.. |. . |.| ....|| .|||| ||.... .||. . |. ....
teeeengkekcdrywpeesggketfgkisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.....
eeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisaaNPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQR
..|..||||||.||||.....|..| .|. . | .||. .|.||
.....................................................sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqR
ACMVQNVSQYRFVCECICAAY
. |||. ||.|..|.| ...
pgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 644-959 | 1.2e-74 | 246.3 | In-house | 4-262 (263) | alignment | |||
Range on Protein: 644-959
Range on HMM: 4-262/263.0
AQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSL---TGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVML
...| . ..... .|||.|..| ||||..| ||| ||| | .. . |||||||.... ..|||||||| || |||||| .| ... |||
eefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga...nkkkkyIatQgPlpstvedFWrmvweekvkiivml
TTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDEtGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTllqei
| .|.|..||..||| . .. . . .|| . ... .. ... |.. |. . |.| ....|| .|||| ||.... .||. . |. ....
teeeengkekcdrywpeesggketfgkisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.....
eeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisaaNPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQR
..|..||||||.||||.....|..| .|. . | .||. .|.||
.....................................................sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqR
ACMVQNVSQYRFVCECICAAY
. |||. ||.|..|.| ...
pgmvqtleqYlfiyeaileyi
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 666-955 | 2.3e-71 | 235.3 | Pfam-A | 1-233 (235) | alignment | ||
Range on Protein: 666-955
Range on HMM: 1-233/235.0
NAPKNRYRDISPYDCTRVSLVNSL-TGDYINANYVNMEIPggaVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQL
| ||||.|| ||| ||| | .| . ||||||||.. ...||||||| || |||||| || ....||||...|.||.||.|||| . || .
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgyke...kkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
AEGFSVRCLSEKPDETGSFVFREFVLKDKHEQ---RHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARnrtllqeieeslkqvrlmdadadadengglm
. ..|.. ... ... ....|.. ||.| |. |......| .||||.||..|. .|.. ..|. .
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk...............................
rerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
.| . ||.||||||.||||.....|..| .||.| | |.||...| ||. |||...|| |....|
...........................eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 666-955 | 2.3e-71 | 235.3 | In-house | 1-233 (235) | alignment | ||
Range on Protein: 666-955
Range on HMM: 1-233/235.0
NAPKNRYRDISPYDCTRVSLVNSL-TGDYINANYVNMEIPggaVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQL
| ||||.|| ||| ||| | .| . ||||||||.. ...||||||| || |||||| || ....||||...|.||.||.|||| . || .
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgyke...kkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
AEGFSVRCLSEKPDETGSFVFREFVLKDKHEQ---RHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARnrtllqeieeslkqvrlmdadadadengglm
. ..|.. ... ... ....|.. ||.| |. |......| .||||.||..|. .|.. ..|. .
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk...............................
rerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
.| . ||.||||||.||||.....|..| .||.| | |.||...| ||. |||...|| |....|
...........................eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 659-956 | 1.7e-70 | 232.5 | In-house | 2-240 (245) | alignment | ||
Range on Protein: 659-956
Range on HMM: 2-240/245.0
TEARKPANAPKNRYRDISPYDCTRVSLVNS---LTGDYINANYVnmeiP-GGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQY
. |..|.| .||||.|| ||| ||| | . | |||||.|| . ...|||||||..|. |||||.... .. .||||. .| ||.||.||
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyv....dgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqy
WPVtgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRaarnrtllqeieeslkqvrlmdada
|| .| . ..|.|..|||. .... |.. .. ..|.|...|..|| ||||.||....|.|.| |.||
wpl..gesltygdftvtllseeh..lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvr.........................
dadengglmrerkcaasngatpedetpvstsvhQCIS-AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFV
.... .| ||.||||||.||||..|.....| ..|.. | . ..|. .|.|| ..||. |||||.
.................................kalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrfl
CECIC
|...
yeall
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 659-957 | 5.4e-70 | 231.1 | In-house | 4-244 (249) | alignment | ||
Range on Protein: 659-957
Range on HMM: 4-244/249.0
TEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEIPGGAvnrYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
..|..|.| .||||.|| ||| .|| | .|||||.|... . . .||||||| .|. |||||.... .. .||||. .| ||.||.|||
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrr...fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw
PVtgEELQLAEGFSVRCLSEKPdeTGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRaarnrtllqeieeslkqvrlmdadad
| .. . ..|.|..||.. .... |.. |. . | |...|.||. |||| ||.... .|.| |.||
pl..ggsleygdftvtllsvev..kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavr..........................
adengglmrerkcaasngatpedetpvstsvhQCIS--AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFV
.... . ||.||||||.||||..|.....| ..| . | ....|...|.|| ..||| .||||.
................................kaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrfl
CECICA
.|...
yealle
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 660-956 | 2.3e-69 | 228.9 | In-house | 4-239 (243) | alignment | ||
Range on Protein: 660-956
Range on HMM: 4-239/243.0
EARKPANAPKNRYRDISPYDCTRVSLvNSltGDYINANYVNMEiPggavnRYIATQGPLASTTTD----FWRMVQQESSHLLVMLTTVMESGRQKCHQYW
|..|.| .||||.|| |||..|| | .. .||||||.... | |.||||||| .|. | ||||.... .. .||||. .| ||.||.|||
iallpenlsknrysdilpydhsrvkl.eg..sdyinanliyvt.p.....rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PvtGEElqLAEGFSVRCLSEKPdeTGSFVFREFVLKD---KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEieeslkqvrlmdada
| ||. ..|.|..|||. ..... |...|. ....|...| .||.||||.||..|. .|.| . ||. ...|.
p..gev..tygdftvtllseeh..lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsll...............
dadengglmrerkcaasngatpedetpvstsvhqcISAANPPVIVHCSAGIGRTGVLILMDTALALMearePVYPLDIVRTMRDQRAC-MVQNVSQYRFV
. ||.||||||.||||.||.... | |. | ....|...|.|| . .||. |||||.
...................................aldsggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrfl
CECIC
|...
yeall
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 662-959 | 5.2e-58 | 191.3 | In-house | 24-268 (274) | alignment | ||
Range on Protein: 662-959
Range on HMM: 24-268/274.0
RKPANAPKNRYRDISPYDCTRVSL----VNSLTGDYINANYVNMeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV
. . .. ||||..| | . .||.| ... .||||||. ... . |.||||||..| .|||||. ||.....|||| . |. .|||..|.|
dvfgsqtknryktilPnensrvllesessededssyinanyikG..ydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPd
TGeELQLAEGF-SVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVraarnrtllqeieeslkqvrlM--------
. .....| . | || |. . |..||| ...|...|. | .|||| .| |.| .|.. . |
ae.dyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvlev.....................eesreeena
----DadadadengglmrerkcaasngatpedetpvstsvhqcisaanppvIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQN
.|||||||||||. | .. |. ..... | | || .| .| |||.
klapv..............................................vvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqt
VSQYRFVCECICAAY
.||... . .|
seqyelihralclyl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 658-832 | 2.2e-54 | 179.6 | In-house | 46-221 (306) | alignment | ||
Range on Protein: 658-832
Range on HMM: 46-221/306.0
ITEARKPANAPKNRYRDISPYDCTRVSL-VNSLTG-DYINANYVNMEIPGGAvNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
.|..|| |. ||||. | |.| |||.| .|..| |||||||.. |..| ..|||||| | .| .|||||| ||.|...||.|. .| |..|| .||
rkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsd.ksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYW
PVTGEELQlAEGFSVRCLSEkpDETGSFVFREFVL---KDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
| . |. . ||...|| ... ....||... |.|.|.|....... .|||| ||.||. .|.| | |.. ...
Pdeeekee.yGkisvtnvse..ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqee
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 651-831 | 7.4e-54 | 178.3 | In-house | 33-211 (564) | alignment | ||
Range on Protein: 651-831
Range on HMM: 33-211/564.0
RKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESG
.... ...|.|||| .|||| .| .|| .|| | . |||||.... . . |||||||||.|. |||||| .. |. |||| . |.|
eegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr...krkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkg
RQKCHQYWPVTGeELQLaEGFSVRCLSEKpdETGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
..|||.||| .| . . ... | .|. | ...|.| || ...|.| ... .. .||||.|| .. .|.. ..|||...
kvkchkYWPekg.tety.geltVtleeee..eladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 644-833 | 9.2e-52 | 170.9 | In-house | 29-215 (293) | alignment | ||
Range on Protein: 644-833
Range on HMM: 29-215/293.0
AQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYvnmeIPGGA-VNRYIATQGPLASTTTDFWRMVQQESSHLLVM
.|| . . | |.. |....|. ||||..| ||| .|| | .. . ||||||| ||| . .||||||| .|. |||||| .. |. .||
eeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinany....ipgynsprefiatqGPlpetvddfWrmvwekkssiivm
LTTVMESGRQKCHQYWPVTGEELQLAeGFSVRCLSEKpdETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRT
|| ..| |..||..||| . |. . .| ..|. |. .| ||. .. ..|.|.........|||| ||.... .|.|...|| | ..|
ltqlvekgkvkCeeYWPadeepvlyG.dikvtlvaee..eledwvirelkiekekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiekt
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 650-829 | 1.3e-47 | 157.0 | In-house | 16-194 (290) | alignment | ||
Range on Protein: 650-829
Range on HMM: 16-194/290.0
YRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTgDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQ
.. |. ..||..|.| ..|||||.|||| .|. | .. . |||||. |..| | .|| |||||..|.. ||.|| .. |. .||| |.| ...
rkeasdfptreaklpenrnlnryrdvspydhsrikleradn.dyinaslvelee...akrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqi
KCHQYWPVTGE--ELQLA-EGFSVRCLSEkpDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
||.|||| | ||.| ..|. .|| ... .. | . |.. .| |.| |. |..||| ||. |. ||.| .|| .
kcaqywPqgeeekellledtklkvklise..erksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvres
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 645-831 | 1.4e-46 | 153.8 | In-house | 26-209 (288) | alignment | ||
Range on Protein: 645-831
Range on HMM: 26-209/288.0
QYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
.|. . . . . | .|.. ||.|||||.| ||| .|| | . . |||||.|.. | . ..|||||||||.| |||..| .. .. .||||
eynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidge...kkkkkyiatqgPladtvndfWelvyenktstivmlt
TVMESGRQKCHQYWPVTGEElQLAEGFSVRCLSEKpdETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
..| |..||..||| .... .. . | ...| |...|| |.. |. |.....|...|||||||| || . . .||. . | | .
elveggktkCeeYWPdadkp.knyGsvtvtlvesk..eledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 644-832 | 7.5e-46 | 151.5 | In-house | 19-205 (281) | alignment | ||
Range on Protein: 644-832
Range on HMM: 19-205/281.0
AQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVML
.|| .. . | . | .....| ||||..|. || ||| . .. . ||||||.|. ..|||||||. .. ..||.|| ... ...||.
eeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgy...kgekeyiatqgPvPaslvafWqmvweqkvsaivmv
TTVMESGRQKCHQYWPVTGEELQLAEgFSVRCLSEkpDETGSFVFREFVL-KDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
| .|.|. |||.||| .||.... . |. ..| |. ... |.| | ... |.|......|.||||| ||.... .||| . |. ....
treieagklkChrYWPddnselkygd.vtvkstae..eekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltek
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 647-831 | 1e-45 | 150.9 | In-house | 21-204 (290) | alignment | ||
Range on Protein: 647-831
Range on HMM: 21-204/290.0
ELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLT---GDYINANYVNMeiPGGaVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTV
. |... ....|. | ||||.|| ||| .|| | . ||||||... . | .|||.||||. | .|||||... . ...||. .
sekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikg..veg.kleyiaaqgPLpktlddfWrmiweknveivvmaCre
MESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGsFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
.| |..||..||| .||| . |.| . .|| . . |. | . .. ..|.|... ..| ||||| ||| .. ||..| || ..
velgkkkCerYWpeegeeelefgefevtleeekavddd.flirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 666-959 | 1.9e-45 | 150.0 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 666-959
Range on HMM: 1-171/182.0
NAPKNRYRDISPYDCTRvslvnslTGDYINANYVNMEIPGGAvnrYIATQGPLASTTTDFWRMVQQESSHLLVMLTtvmesgrqkCHQYWPvtgeelqla
| .||||.|| ||| .| ||||||.. . |. .||||||| ||. ||.||.... ...|.|| ...|||
nldknrysdilpydhsr.......dldyInanlylgslpatr...fiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
egfsvrclsekpdetgsfvfrefvlkdKHEQRHIHHMQYLAWPDHCVPSdPNLFLEFTERVRAarNrtllqeieeslkqvrlmdadadadengglmrerk
....|.... .|| ||||.||. .. .|.| |.|.. .
...........................ellerlgiqylylpwpDhgvpd.ldelldfieevle..e..................................
caasngatpedetpvstsvhqcisaaNPPVIVHCSAGIGRTGVLILMDtalaLMEAREpVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAY
. ||.||||||.||||.|.... ||. .. | . ..|...| .| .||.. .||.|. ... .
..........................ggpvlVHCsaGvgRtgtlvaay....lmkklg.vsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 633-833 | 5.4e-45 | 148.7 | In-house | 16-219 (300) | alignment | ||
Range on Protein: 633-833
Range on HMM: 16-219/300.0
LSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSL--TGDYINANYVNMEIpGGAVNRYIATQGPLASTTTDFWRMVQ
| | .| . ..|| . .|. | .. |. | ||.|||..|. ||. .|| |. . . .|||| ... . ||. ||..|||| | .|||.||
lekkleegkvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsv.ggkersyivaqgPleltvqdfWqmvW
QESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
.. .|.|||| |.|..|...|.| .... . .| . .. ....|.. . . || .|.| ..|.|| |||| ||.|.. ||.. |.|..
eqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqs
ARNRT
|..|
vrrkt
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 649-829 | 1.2e-44 | 147.6 | In-house | 20-198 (273) | alignment | ||
Range on Protein: 649-829
Range on HMM: 20-198/273.0
MYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTgdYINANYVNMEIpGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGR
. | . ....| .| |||||.. ||| ||| | .. . ||||....... | .|||.|||| |..|||.|| . ......|.|. |.|.
lrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg..yinaslikvpv.gkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgk
QKCHQYWPVTG-EELQLAEGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
|||.|||.. ..|.. . . |. | . .|| |.. .||.. | |.. |... .|||| ||| .. .|.| .||
vkchrywPesknkklkvsnrlevellkv..qkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrl
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 642-832 | 1.7e-43 | 143.7 | In-house | 18-208 (297) | alignment | ||
Range on Protein: 642-832
Range on HMM: 18-208/297.0
LLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLV
| .|. . .... .. ....|| |||| |. || ||| | . . ||||||.|. . .||||||| |..|||||| ... .|
lskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGy...kqkkafiatqGplkktvsdfWrmvWeqevlviv
MLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKpdETGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
| | |.| || || |||| . |. . .||. .. . |. ...| ...| ...|.|.. | |.|.|||. |||. . .|.. | || ..
mttrvvergrlkcgqyWpleeessaefgdlsvsnveve..eeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqal
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 643-830 | 1.9e-43 | 143.7 | In-house | 23-208 (318) | alignment | ||
Range on Protein: 643-830
Range on HMM: 23-208/318.0
LAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLV---NSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
..|| . |.. . ... .|.|. |||| .| .|| ||| | .. . |||||||.. . . |||.|.||. | .|||||| . | ..||
seeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyr...rkkayiaaqaPlpetieDfWrmvWeqnsavivm
LTTVMESGRQKCHQYWPVTGEelQLAEGFSVRCLSEKpdETGSFVFREFVLKDK--HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
|| ..|.|..|.|.||| | . . | .|. |....| ||| .. . .|.|... .| .|||. ||... .|.. .|..|
ltqeeergkakvhryWPskgs..rsygklvvelkeev..elsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaq
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 691-952 | 4.2e-43 | 142.4 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 691-952
Range on HMM: 2-163/174.0
GDYINANYVNMEIPGGavnRYIATQGPLAstttdFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVtgeelqlaegfsvrclsekpdetgsfvfrefvl
|||||..... . . |.||.||||| ||.|....... .|||.. .| |. ||..|||
sdyinaspldlsyitp...rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.................................
KDKHEQRHIHHMQYLAWPDHCVPSDPNlFLEFTERVRAARnrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisA
. ... |.... .|| ||||.||... .||| ..|. |. .
lredlerlgiqylylpwpDhgvpdlsi.llefvkfveeal...........................................................s
--ANPPVIVHCSAGIGRTGVLILMDTALALMEaREPVYPLDIVRTMRDQRACMVQNVSQYRFVC
. ||.||||||.||||.|.... | ... .| ||.||..| || .|||. |||||.
edpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 642-824 | 2e-42 | 140.1 | In-house | 9-191 (297) | alignment | ||
Range on Protein: 642-824
Range on HMM: 9-191/297.0
LLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTG-DYINANYVNMEIpGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVML
| |...|..... . . |.... ||||||| .| ||| | .. |. |||||.|| . | .|| .|||| .| |||..| .. .||.
leaekdllldeargesfssakrnsslrknryrdilatddtrvkllrviterdyinadyvvfpd.eeadlkyilaqGplsatvddfwtlvaeqdvrvivmv
TTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTE
. . | ||.|| ||| . .| . | . | ||. || .. |. | . |.|...|.|.|.|||| |||| . |
aklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqa
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 657-831 | 5.2e-42 | 139.1 | In-house | 47-219 (298) | alignment | ||
Range on Protein: 657-831
Range on HMM: 47-219/298.0
AITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNmeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQ
. ||||.| |||| || ..| .|| | . .||||| ... | .||||.|| .|..|||||| .| . .||||.. |... |.|.
ekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflh...aykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhk
YWPVTGEELqlAEGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
||| .|.| . ..|. ||. .| . .. |.. ...|. ..|....... |||..||. . |.. ..||| ..
ywPdegket..ygeitvsllsk..eefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqq
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 654-830 | 2e-41 | 136.7 | In-house | 33-204 (288) | alignment | ||
Range on Protein: 654-830
Range on HMM: 33-204/288.0
PDLAITEARKpaNAPKNRYRDISPYDCTRVSLVnSLTGDYINANYVNMEIPGGavNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQ
. .|. |.. .. |||.||| ||| .|| | . . ||||| .|. || .||||.||.|| |||.|| .. | ..|||.. | |..|...
rkrsiaiakl..yseknrsrdilPyDhnRvklr.gskDDYinAsfvkdlspgc..PdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdr
YWPVTGEELQLAEGFSVRCLSEKpdETGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
||| .| . . .|| . |.. ||. .| |.. |. |... ... |.|. .||.. ||. |. .|.| . |..|
YwPedkgetvkfgdlsvtlksvr..etethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesay
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 646-833 | 8.7e-41 | 135.0 | In-house | 29-214 (319) | alignment | ||
Range on Protein: 646-833
Range on HMM: 29-214/319.0
YELMYRKNPDlAITEARKPANAPKNRYRDISPYDCTRVSLV---NSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTT
..|. ..| ...| |. | .||||..| .|| ||| | .. |||||.... ...||||.||. |. |||||| .| |. .||||
fkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgy...qerekfiatqaPlentiedfWrmvWeeessivvmltk
VMESGRQKCHQYWPVTgeElQLAEGFSVRCLsEKPDETGSFVFREFVLKDKHE---QRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRT
. | .. |...||| . . | . | |. .|. .. |.. |. | . |.. | ||..|||| || . . |.. .|.| .|..|
lveklkvklkkywpee..n.feeyGrlivtl.eeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrekt
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 661-832 | 1.3e-39 | 130.9 | In-house | 4-172 (250) | alignment | ||
Range on Protein: 661-832
Range on HMM: 4-172/250.0
ARKPANAPKNRYRDISPYDCTRVSLVNSL---TGDYINANYVNMEIpgGAvNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQkCHQYWPV
|.||.| |||| || ..| .|| | .. ||||| ... . . .||||||| .|. |||||| .| | .||||.. ||... .||||||
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyd..er.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
TGEElqLAEGFSVRCLSEkpDETGSFVFREFVLKDKHEQR--HIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
. | . | ||. .| . .. |...| .... .. ......||| .|| . ||. ..|.| ...
ekae..kyGdvtvsllsk..eefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqq
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 691-952 | 2.2e-39 | 130.3 | In-house | 5-154 (172) | alignment | ||
Range on Protein: 691-952
Range on HMM: 5-154/172.0
GDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVmesgrqkchqywpvtgeelqlaegfsvrclsekpdetgsfvfrefVL
|||||.|... . .|.||||||| .|. |||||.... ...|.||. ..
sdyinasyldlyy...ipdrfiatqgplrntladfwrmlkelgithivnltel.............................................ly
KDKHEQRHIHHMQYLAWPDHCVPsDPNLFLEFTERVRA--ARNRtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqci
....|.. . .|| ||||.|| ...|.||| | .. |...
dpellerlgiqylylpwpDhgvp.llellleflefidellalsp........................................................
saaNPPVIVHCSAGIGRTGVLILMDTALalmearEPVYPLDIVRTMRDQRACMVQNVSQYRFVC
. ||.||||||.||||.|.... | . . ....|...|..| ..||| |||||..
...ggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrfly
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 642-832 | 1.3e-38 | 127.6 | In-house | 21-218 (563) | alignment | ||
Range on Protein: 642-832
Range on HMM: 21-218/563.0
LLAQYE-LMYRKN-PDLAITEARKPANAPKNRYRDISPYDCTRVSLVnSLTG-----DYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESS
. ...| |. . . || .. ..|| | |||| .| .|| .||.| .|.| |||||||.. . .|||||||..|. |||||. .. .
fseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvkls.plpgkkkklDYinAnyidGy...qkskafiatqgplkdtfddFWrmiWeqnv
HLLVMLTTVMESGRQKCHQYWPVtgEELQLAEGFSVRCLSEKPDET---GSFVFREFVLKDKHE---QRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
...||.| . |.||.||..||| .| . . ..|. .|. . ..| ... ||.|.. .... . .| ||||.||. . | | .. |
aiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssa
ARNR
|...
anka
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 659-955 | 2.2e-38 | 126.7 | In-house | 21-311 (319) | alignment | ||
Range on Protein: 659-955
Range on HMM: 21-311/319.0
TEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
... .. .|.|. .. | ||| | . |..|.|| . | | |||.| .| ....||||.| . | .| || . | | ..| .|.
adevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrG..yddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeyl
PV--TGEELQLAEGFSVRClseKPDET-GSFVFREFVLK--DKHEQRHIHHMQYlAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDA
| |... .| . | | |. .. ..|| ||.| |.. | | |.. ||.... .. .||.. . |.. .| .. ...
PtketldntslyGdilvtl...kgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrsslksysleqanelreksatlet
DADADENgglmrerkcAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAR-EPVYPLDIVRTMRDQRACMVQNVSQYR
||| . | |.| | | . . |..|||| |.||||..| | |. .| . | ..| .| .|| |... ||
smdadgs.........kaeagstssheingnissrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqye
FVCECI
|. .
fiykvl
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 666-817 | 5e-37 | 122.3 | In-house | 20-172 (270) | alignment | ||
Range on Protein: 666-817
Range on HMM: 20-172/270.0
NAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNmeIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEEL
.. |||.|| | ||| | . . |||||||. |. ..|||..|||..|...||||. .| .. .||.| ..| ||.|| .||| .|
gkklnRyadiLPsPatRvrleeleedsataYinAnyvr..GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
QLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPN
| .. |... . ..... |..| |.|.. | .| .|||| ||....
vkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreed
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 659-830 | 1.2e-36 | 121.2 | In-house | 36-206 (314) | alignment | ||
Range on Protein: 659-830
Range on HMM: 36-206/314.0
TEARKPANAPKNRYRDISPYDCTRVSLVNsLTG----DYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQY
|.| | |||. || .|| .|| |. . | |||||.... . .|.||||| .|..||||.| .| . .|||| ..| || || .|
daakkdenreknrsgdilaydrsrvflit.idgdpssdyinaalidsy...krpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClky
WPVTGEElqlAEGFSVRCLSEKPDEtgSFVFREFVLKD----KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
|| .| . . | ... .... .| | | .. ..|.| ....|.|.|||| || . .|.. || . .
WPedtev...ygdikvelvetella..elvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksq
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 653-955 | 3.5e-36 | 120.9 | In-house | 33-276 (314) | alignment | ||
Range on Protein: 653-955
Range on HMM: 33-276/314.0
NPDLAITEARKPANAPKNRYRDISPYDcTRVSLvN---SLTGDYINANYVNMEipggavNRYIATQGPLASTTTDF----------WRMV--QQESSHLL
|.| |. |....| |||| || |.| .|| | . . |||||.||. ...||||||| | || |||| .. .. .
lpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf......lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdi
VM---------------------LTTVMESGrqkcHQYWPVTGEELQlaegfsvrclsekpdetgsfvfrEFVLKDKHEQRHIHHMQYLAWPDHCVPsDP
|| |..... | .... . |.|. | . ... .|.. . .. .||...| ..
vmsrdevladelsrLdaAlgKtpllildgng....neptaadlellk.......................eelydpelferlgikylripvpDgsap.ll
NLFLEFTERVRAArNrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisaANPPVIVHCSAGIGRTGVLILMDTAL
. |.|| | ...| . .. ||.|||.||.||||...... .
edfdeflefieea.d...........................................................kggpvlvHCkaGkgRtgtfvvaaylm
ALMearePVYPLDIVRTMRDQRA-----CMVQNVSQYRFVCECI
|. | . .... .| .| .... || |. |..
kll....gvsleealedvrlkRpinpnpgfieqleqyefileal
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 641-832 | 7.5e-36 | 118.8 | In-house | 23-213 (305) | alignment | ||
Range on Protein: 641-832
Range on HMM: 23-213/305.0
ALLAQYELMYRKNPDLAITeaRKPANAPKNRYRDISPYDCTRVSLVNSLTG---DYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLL
.| |||...|... . .. .| ||. |||...| ..| |. | .. . |||||.||. ..||..|||| .| .||||.. .| . .
gleaqykslyeeeesidvg..kkeankaknrlkeitlldddriiltekeslddsdyinasyvdgy...krkkkyivaqgPlkntvadfWrliveekvsti
VMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKpdETGSFVFREFVLKD---KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
|||| ..| |..||.|||| . | . . ||| ||| .. .. |.. . ..|.| . ..| |||| || . .|.. .||. ....
vmltklveggkdkCrqYWpesktekkefgefsvelksek..tasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 643-829 | 1.3e-35 | 118.1 | In-house | 25-214 (307) | alignment | ||
Range on Protein: 643-829
Range on HMM: 25-214/307.0
LAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNmeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
. || . ... |. . . | || |||| || ..| ||| | . . . |||||.... ...|| |.|. .| |||||. . ...|.||
akeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfik...gykekkkfiaaqdPveatigDfWRmiaeqevtlivm
LTTVMESGRQKCHQYWPVTgEELQLAeGFSVRCLSEKpdETGSFVFREFVLKDKH-------EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
|. . | |.||..|||. .| | |.. ||. ... .. ||. . |. ..|.. .|..|.| || .. |.. |.||
lsnlteknrkkcakYWpie.devqyg.dilvklvsee..khsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrel
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 659-823 | 8.3e-34 | 111.7 | In-house | 31-194 (287) | alignment | ||
Range on Protein: 659-823
Range on HMM: 31-194/287.0
TEARKPANAPKNRYRDISPYDCTRVSLVN--SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWP
.| . |.. |||| |. |.| ||| |.. | |||||||| ...||.|||.|.| ||||.| .. | ....| .| .|.||..|||
kaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasy...tddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywP
VTGEELQLAeGFSVRCLSEKPDETGsFVFREFVLKDK--HEQRHIHHMQYLAWPDHCVPSDPNLFLEFT
... |.|| |. . | . | . | | .| | .. ...|.|||. .. .. |.
erevPmrvG.GysvvlldydikePe.ygvralrlidletrearvvkqldllswPdkvlaPtavglirfv
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 653-832 | 1.1e-33 | 111.5 | In-house | 30-208 (315) | alignment | ||
Range on Protein: 653-832
Range on HMM: 30-208/315.0
NPDL-AITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNmeipGGAV-NRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESG
.|| . ||.. | .||||..| |.| .|| | .| ||||| |.. . . |||.|||| .. |||||| || .||.| |.
dPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyik....svdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegd
RQKCHQYWPV-TGEELQLaEGFSVRCLSEKPDetGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
. || |||| .. .. ..| || ..| . | |..|... .|.| . |. |||. |. . .|.. |.| ...
kikcrqywPdrkadsvef.Gsikvellslead..tdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 659-831 | 1.6e-33 | 111.0 | In-house | 51-225 (330) | alignment | ||
Range on Protein: 659-831
Range on HMM: 51-225/330.0
TEARKPANAPKNRYRDISPYDCTRVSLVNS---LTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
| | | |||. .| ||| .|| | . . ||||| ... ...||.|||.. | |||||. . |. .|||| . | ..||.|||
elaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGy...kekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqyw
PVTGeelQLAEGfSVRCLSEKPDETGSFVFREFVLK------DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
| | .. | .| |. .. .. |.|... .....| .. . . .||| ||..| |.. ..|.. ..
PdeG...lvtyG.nirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnq
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 667-826 | 4.2e-33 | 109.2 | In-house | 57-212 (290) | alignment | ||
Range on Protein: 667-826
Range on HMM: 57-212/290.0
APKNRYRDISPYDCTRVSLVNSLTGDYINANYVNmeipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAE
||||.|. | ||| | . |||. ||||. | .| |||.|..|. |.|||| || .||| ..| |. ||.||.| . |
fkknrykdvvcndktrvilkdGydGdyvhanyvk.....GlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfG
GFSVRCLSEKpDETGSFVFREFVLKDKHE--QRHIHHMQYLAWPDHCVPSDPNLFLEFTERV
..| | |. |. . . . ..||.. . ..|.. .|||..|. .| .
eitvlcseed.dkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlril
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 650-827 | 3.7e-32 | 106.2 | In-house | 41-217 (297) | alignment | ||
Range on Protein: 650-827
Range on HMM: 41-217/297.0
YRKNPDlAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEIPGGAVnrYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMES
|. .| . . |... |. |||.... ||| .||.| . . . ||||| . . | .. ||||||||||| .|||.|| .. . ..|.||.. |.
yeaeps.tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapa..yiatqgplastvadfwqmvweqGvvvivnltrleee
GRQKCHQYWPVTGEELQlaEGFSVRCLSEKPdETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVR
| ..|..||| .|.|. . . |. .||. . .. | | ||. ..| | . . .|.||.. ||. .. .||| .|
gvkqckrywpdeGsevy..hiyevhlvsehi.wcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvn
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 666-826 | 4.9e-32 | 106.0 | In-house | 3-162 (237) | alignment | ||
Range on Protein: 666-826
Range on HMM: 3-162/237.0
NAPKNRYRDISPYDCTRVSLVNSL-TGDYINANYVNMeIpGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELql
| |||| .| || .|| | . . |||||.|.. . |. ..|||.|||| |. |||.|| || ..|||| ..|. ..|||.||| | .
nkiknrygnivaydhsrvvlkgagsgsdyinatylkg.f.dgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpa..
AEGFSVRCLSeKPDETGSFVFREFVLKDKH---EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERV
| | | | .| . | ..| .. | | || |. .|||. || .| | ..
aygvltvslk.kkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkni
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 658-829 | 1.9e-31 | 104.6 | In-house | 53-217 (319) | alignment | ||
Range on Protein: 658-829
Range on HMM: 53-217/319.0
ITEARKPANAPKNRYRDISPYDCTRVSLVNS---LTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTtvmesgRQKCHQY
| | . | |||. .| ..| ..| | . ||||| .|. ..|||.|||| | |||||. . . .|.|| ..|| ||
qtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGy...qrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqy
WPVTGEELQLAEGFSVRCLsekpDETGSFVFREFVLKD---KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
|| ... . .| . .|| .| |.. | . ....|.|. .| |||. || | .. . ..||
wplkivikeerfkvkvdsv....eetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhl
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 677-954 | 3.3e-31 | 103.7 | In-house | 1-166 (178) | alignment | ||
Range on Protein: 677-954
Range on HMM: 1-166/178.0
PYDCTRVSLVNSLT---GDYINANYVNmeiPGgavnRYIATQGPlasttTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEelqlaegfsvrcl
|.| |||.| | .|||||... || |.....| |........ ...|.||. .| |..||..||| .
pldrtrvllsnleglersdyinaseil...pg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.............
sekpdetgsfvfrefvlkdkheqrhiHHMQYLAWPDHCVPSDPNLFLEFTERVRAARnrtllqeieeslkqvrlmdadadadengglmrerkcaasngat
..... .|||.||. . ||||.| ...|.
..........................iqylhipipDhgvpdllehflefvefieeal...........................................
pedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLIlmdtALALMEARePVYPLDIVRTMRDQRAcMVQNVSQYRFVCEC
. . ||.||||||.||.|.|. |. || . . . .... .| .| .|.| .|.|...|.
...............dekggpvlVHCsaGvgRsgtlv....aaylmkkl.glsleeaielvrerRp.ivpnpgqlrqLyef
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 645-833 | 6.4e-31 | 102.4 | In-house | 25-210 (287) | alignment | ||
Range on Protein: 645-833
Range on HMM: 25-210/287.0
QYELMYR-KNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVnSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTV
|. .. . .. . .| . . | .|||...| ..| || | ||||| ... ...|....|...| .||...... . .|||.
qftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk.gehpdyinavfidgy...kekkafiiaesPmfntarnfWkliddrnvtaivmlcqe
MESGRQKCHQYWPVTGEeLQLAEgFSVRCLSEKpdETGSFVFREFVLKDKH---EQRHIHHMQYLAWPDHC-VPSDPNLFLEFTERVRAARNRT
.|. ...|.|||| . . | | .... |.|. . ... |.. .| |. ...... |. .|... |.. .| . |.... | |.
kendeevcyqyWpeeks.vvlGe.yniellnee..vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrg
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 659-829 | 6.8e-31 | 102.8 | In-house | 18-181 (284) | alignment | ||
Range on Protein: 659-829
Range on HMM: 18-181/284.0
TEARKPANAPKNRYRDISPYDCTRVSLVNS---LTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTtvmesgRQKCHQYW
| | . | |||. .| ..| ..| | . ||||| ... ..|||||||| | |||||. . . .|.|| ..|| |||
tfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGy...qrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqyw
PVTGEELQLAEGFSVRCLsekpDETGSFVFREFVLKD---KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
| ... . .| . .|. .| |.. | . ....|.|. . .| |||. || | .. . ..||
plkivikeerfkvkvdsv....eeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhl
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 659-832 | 1.6e-30 | 100.7 | In-house | 36-207 (515) | alignment | ||
Range on Protein: 659-832
Range on HMM: 36-207/515.0
TEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNmeipGGA-VNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQY
| |.. | .||||..| ||| .|| | .. ||.|| |.. . . |||.|||. ... ||||.| || ..|.| |. . || .|
tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyip....sfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgky
WPV-TGEELQLAEgFSVRCLSEKPDeTGSfVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
|| |. ... . ..| .| . . || . |.. . . | . .. |||. || . . .| . |.| ...
WPdkpgdsvkfGs.ikvelvsleac.tgg.ikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgq
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 654-811 | 3.3e-30 | 99.9 | In-house | 21-175 (283) | alignment | ||
Range on Protein: 654-811
Range on HMM: 21-175/283.0
PDLAITEARKPANAPKNRYRDISPYDCTRVSLvNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQ
||| . | | .|||...| |.| || | .|.. ||||| .. .. ..||..|.|| | |||.|| .| .|||| ..| |.|| |
pdldadiasadenkrknrnqeivpadqwrvel.ksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsq
YWPVTGEElQLAEgFSVRCLSEKpdETGSFVFREFVLKDK---HEQRHIHHMQYLAWpDHC
||| | | . | | | | ||. .|..|. . ... . | |. | ..
yWPkrGse.dyGe.ftvtlrket..tsnsfiikelllrvnssakstlllahyqvidW.ley
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 641-828 | 3.6e-30 | 100.0 | In-house | 17-207 (307) | alignment | ||
Range on Protein: 641-828
Range on HMM: 17-207/307.0
ALLAQYELMYRKNPDLAITEARKpANAPKNRYRDISPYDCTRVSL-VNSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
|| ... . .|.|. .|| . ||. ||||.|. | .|. . .. |. ||| |||. . | ...|..|||| .| .|| |. || ..|
alvdefrvlakktpegvtveafs.antdknryqdvkcqdkgrivvkfdglasdyihanylgiai...kpkkficaqgplentqysfwamaiqekvesvim
LTTVMESGRQKCHQYWPVT-GEELQLAE---GFSVRCLSEK---PDETGSFVfREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
| |.| .. ||.||||. |..| .| || | | ||| | .. .. .. | |.|.|. |||. || ... | ||
lckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinv.ttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 645-833 | 1e-29 | 98.3 | In-house | 25-215 (290) | alignment | ||
Range on Protein: 645-833
Range on HMM: 25-215/290.0
QYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLV-----NSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
|.. . . . ..| . . | ..||...| .|| |. | . | .|||| |.. ..|||||||. .| |||....||.. .||
qfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgy...kekkqyiatqgpvsntlvdFWkliwqekvtiivm
LTTVMESGRQKCHQYWPVTGEELqlAEGFSVRCLSEKPDEtgSFVFREFVLKDKHE---QRHIHHMQYLAWPDHC-VPSDPNLFLEFTERVRAARNRT
||...|.|..||.|||| .. . . ||.. |.|. . ... |.. .|.|.. ...... | .|... |. | ..|... | |.
ltniieegkvkCqqYWpdsdtka..ygefsikllneetln..eyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrg
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 655-832 | 3.8e-29 | 96.8 | In-house | 37-213 (325) | alignment | ||
Range on Protein: 655-832
Range on HMM: 37-213/325.0
DLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHlLVMLTTVMESGRQKC
| . | ||.| |||.... ..| .|| |. . |||||.|.. .. . ..|.| ||..|. |.||.| . . .|... ... | ..|
giakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddk...kkdvflaaqaPltatindlWrlvldWrcs.vvvvlneldlgkdrc
HQYWPVT-GEELQLaEGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
.||| |. .. |. |. . .| .| | . .|. . | | .. .|. .|.| |. | .. ... | | .|
avywpkemgksktf.Gglevklrti..eeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavser
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 692-953 | 7.5e-29 | 95.7 | In-house | 4-147 (151) | alignment | ||
Range on Protein: 692-953
Range on HMM: 4-147/151.0
DYINANYVNmeipGGavnrYIATQGPLAstttDFWRMVQQESSHLLVMLTTVMESGrqKCHQYWPVTGeelqlaegfsvrclsekpdetgsfvfrefvlk
||||..|| || .....|||| ||....... |.|.. .| | .|..|.| .|
dyinfsyvt....gg....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg................................
dkheqRHIHHMQYLAWPDHCvpsdpnlfleftervraarnrtllqeieeslkqvrlmdadadadengglmrerkcaasngaTPEDETPVSTSVHQCISAA
....|...| |||. .|. | ......
.....ievlhipildwpdpg.............................................................lplsfdavleflellldkk
NPPVIVHCSAGIGRTGVLILMDTALaLMearepVYPLDIVRTMRDQRACMVQNVSQYRFVCE
| ||.||||||.||||.|.... | |. | . .... .| .| .|| |..|.
ngpvlvHCsaGkgRTGtlvalylml.lg.....vsleealeeyrlkrpgvvqpnqqflfqlf
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 659-829 | 1.8e-28 | 94.4 | In-house | 42-207 (315) | alignment | ||
Range on Protein: 659-829
Range on HMM: 42-207/315.0
TEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
|.| | |||| .| .|| .|| | | ||.|||... .||||.|||.... ||||.| .| .|||| ..| ..|. .||
dvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGy...nkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekyw
PVTgeELQLAeGFSVRCLSEKPDEtgSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
| .. ..| ||. . . | . . . |.. ..| .||| || .... .|.
pdk..kviyG.kitvtrkseevnt..eytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqh
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 658-827 | 6.2e-28 | 92.8 | In-house | 43-209 (297) | alignment | ||
Range on Protein: 658-827
Range on HMM: 43-209/297.0
ITEARKPANAPKNRYRDISPYDCTRVSLV--NSL-TGDYINANYVNmeipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRqKCHQY
| |.| | .|.||..| ||| || | |. ||.|| .|. | .|.|.|| | .| |||.|| .| .|||. |. . || .|
qtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvk.....gnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcary
WPVTGEELqlAEGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPS--DPNLFLEFTERVR
|. .| || || .| |. ||.... . .| .. |.. |||. |. . . .|.. . ||
Wsdkgvtt..fGdvsvvllsv..sereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevr
|
|||||||||
PTPc_DSPc_SM00012 | 799-955 | 8.4e-28 | 92.0 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 799-955
Range on HMM: 2-103/105.0
IHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisaaNPPVIVH
..|..|..||||.||.... .||. . |. .| ..||.||
vkhyhytgwpdhgvPeesdsilellravkknknkses........................................................skpvvVh
CSAGIGRTGVLILMDTALALMEAR-EPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
||||.||||.....|..| .|.. . | ..||. .|.||. |||. || |.....
CsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyral
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 661-815 | 3.7e-27 | 90.0 | In-house | 3-155 (239) | alignment | ||
Range on Protein: 661-815
Range on HMM: 3-155/239.0
ARKPANAPKNRYRDISPYDCTRVS---LVNSLTGDYINANYVNMEipGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV
|.| | |||| .| || .|| | | |||||.|. |. . |||||| .. .. |||||. || ..|||| ..| ..|||||||
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdy..dgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
TGEELqlaegFSVRCLSEKPDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSD
. . .| | . .. | ||. . . |.|.... .. |||. ||
stsky.....cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqy
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 661-815 | 4.6e-27 | 89.7 | In-house | 2-154 (239) | alignment | ||
Range on Protein: 661-815
Range on HMM: 2-154/239.0
ARKPANAPKNRYRDISPYDCTRVS---LVNSLTGDYINANYVNMEipGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV
|.| | |||| .| || .|| | | |||||.|. |. . |||||| .. .. |||||. || ..|||| ..| ..|||||||
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdy..dgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
TGEELqlaegFSVRCLSEKPDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSD
. . .| | . .. | ||. . . |.|.... .. |||. ||
stsky.....cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqy
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 666-830 | 6.4e-26 | 85.7 | In-house | 55-221 (305) | alignment | ||
Range on Protein: 666-830
Range on HMM: 55-221/305.0
NAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV-TGEELQL
. ||||.|. | . | | . ||| |||| | .|.|..|||| | .|| || |. .||| .| |. || ||||. || |.|
aitknryqdvpcqdqsavkldkpspsdyihanyvgc..pmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklel
AEGFSVRCLS-EKPDETGSFVFR-EFVLKD-KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
| | .| || | . . . | .. . |.|. ||| || ||. .| ..
ksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk
|
|||||||||
FERM_C | FERM C-terminal PH-like domain | 236-324 | 9.3e-26 | 80.2 | Pfam-A | 1-88 (90) | alignment | ||
Range on Protein: 236-324
Range on HMM: 1-88/90.0
DSNGKELQLGVSAVGLLVFQHSLRV--NTFSWSKMVKVSFKRKDFFIQLRRepsENYDTLLGFGMSSHKHAKALWKSCVEHHSFFRLKRPH
...|..| |||.| |||.... .. ..|.||.. |.|||.| |.|.|| |.....| | .|... .| |.|.|.|.|..|| .|..
nkkgtdllLGvdakGlliyeknsklsnksFpWseirklsfkekkftiklrd...ekkkdvlkFyssqlrvnklllklcienhdlfrrrrkv
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 659-830 | 9.6e-26 | 85.4 | In-house | 40-219 (418) | alignment | ||
Range on Protein: 659-830
Range on HMM: 40-219/418.0
TEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEIPggavNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
.| | |. |||| .| | . ||| | . |||||||.. | ...|.||||| | .|||||| .. ...|||. | | || .||
segdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp....kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdryw
P--VTGEELQL-------AEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
| . ||.. . .|| . | . |. | . | | | . || |||| .| . | .. . .
peqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrq
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 667-758 | 2.5e-25 | 83.9 | In-house | 48-153 (350) | alignment | ||
Range on Protein: 667-758
Range on HMM: 48-153/350.0
APKNRYRDISPYDCTRVSLVN-----------SLTGDYINANYVNMEIPGGAVN---RYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCH
||||..| ||. .|| | . | |||||||.... .. .| .|||||.|| || ||.... . .....||. .| ...||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
QYWPVT
.||.
rYWqeg
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 658-830 | 4.6e-25 | 82.8 | In-house | 29-200 (281) | alignment | ||
Range on Protein: 658-830
Range on HMM: 29-200/281.0
ITEARKPANAPKNRYRDISPYDCTRVSLV----NSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQ
| .| | |||| .| | .|| | | . ||| |||. . || |||| | .|||||. || . .||| ..|. |.|| .
ctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspf...lkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcae
YWPVTGEELQLAEGFSVRClsEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
|.| . .|| | |.| . | . | | | | . ||| || ...|. ..||
yfprnahcclqfdklsvsy..edstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirars
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 645-833 | 1.5e-24 | 81.2 | In-house | 18-217 (296) | alignment | ||
Range on Protein: 645-833
Range on HMM: 18-217/296.0
QYELMYRKNPDLAITEA---RKPANAPKNRYRDISPYDCTRVSLvNSLTG----DYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLL
.|.|.... | | | . . | |||. .. ||| .|| | ..| | ||||| ||. . . || |..| .| .|||.| .| .. .
eyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvL.ekldGeeksdYinavyvdsfl...kkkeyivteapkketvdefWrlvydeeisav
VMLTTVMESGRqKCHQYWPVTGeELQLAEGFsVRCLSEKpdETGSFVFREFVLKDK------------HEQRHIHHMQYLAWPD-HCVPSDPNLFLEFTE
|.|| ... . ....||| .. . | | | | ..|| . .. |.| |. | |.| ....|. |. . ||. | ..|. .
vvLtktfdfak.mypsywpnks.keqygeif.veiveek..qyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrr
RVRAARNRT
||| |...
rvrlwrekv
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 643-830 | 1.6e-24 | 81.2 | In-house | 25-219 (305) | alignment | ||
Range on Protein: 643-830
Range on HMM: 25-219/305.0
LAQYELMYRKNpDLAITEA-RKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMeiPGgAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
|.. | | | |. .| .. .| ||||.|. | || | .. .|| |||| | .|.| || || | .||| | |. . . ||
raefvamkrfn.dfekmkafkeaqeagknrykdvgcldnnrvklegpwpheyihanyvst..pt.npkrfictqaplektcadfwymclqdkveaifmlc
TVMESGRQKCHQYWPVT-GEELQLAEG---FSVRCLSEKP----DETGS-FVFREFVLKDK-HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
..| | .||..|.. ...|.. |. ||.. | . ... . ..|.. ...|.. | . ||| ||. . ||. |. |...
nllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpsk
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 691-833 | 4.4e-24 | 81.0 | In-house | 4-152 (272) | alignment | ||
Range on Protein: 691-833
Range on HMM: 4-152/272.0
GDYINANYVNMEipgG---AVNRYIATQGPLASTTTDFWRMvQQESSHLLVMLTTVMESGRQKCHQYWP--------VTGEELQLAEGFSVRCLSEKPDE
..||||..|.. | .|.....||| | ||||. ... . |.|....| ||.||..||| . ... . . . .| .
sgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
TGSFVFREFVLK---DKHEQRHIHHMQYLAWPDHCVPSDPnlFLEFTERVRAarNRT
. .. ||..|. . .| |...|..|..||||.||... .||. | ... ..
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld..ggp
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 661-831 | 8e-24 | 78.9 | In-house | 43-208 (439) | alignment | ||
Range on Protein: 661-831
Range on HMM: 43-208/439.0
ARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRqkchqYWPV
| . . .||||.|....| ||| | ||||||.. . ||||||| || ||||.| .. . .|||| ..|| . |||
aaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyy...ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywps
TGEELQlaEGFSVRClsEKPDETGSFVFREFV---LKDKH-EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
.| .||. .. | .| | | .|. .| . ...|.||||. ||.. |.| . .| .
daevcy..gdiavrv..drnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsand
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 642-822 | 1.2e-23 | 78.3 | In-house | 17-213 (301) | alignment | ||
Range on Protein: 642-822
Range on HMM: 17-213/301.0
LLAQYELMYRKNPDLAITEArKPANAPKNRYRDISPYDCTRVSLVNSLT-----GDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHL
. .||. ....... .. . . .|.. ||...|..|| |. | . . .||||.|.. ...||.|||. .| .||||.. ||
feeqykelkegedksctvgl.seenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgy...sekkkfiaaqgpmkktlvdfWrliwqekpvs
LVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEK--PD------------ETG-SFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLE
.||.| |. ..||.|||| . .| . |.| .|. || .. ... |.| | ... ... .| ||.. | .|. |.
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLq
F
v
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 794-955 | 3.9e-23 | 77.1 | In-house | 42-139 (145) | alignment | ||
Range on Protein: 794-955
Range on HMM: 42-139/145.0
HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqcisaaNP
. |.. . .|| ||||.||....|.||| | ...|... .
llerlgiqylylpwpDhgvpdllellleflefieealke...........................................................gg
PVIVHCSAGIGRTGVLILMDtalaLMEAREpVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
||.||||||.||||.|.... || . | . .... .| || ..|.|..|.||..|..
pvlVHCsaGvgRtgtlvaay....lmlllg.vsleealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 640-760 | 1.7e-22 | 74.4 | In-house | 27-145 (310) | alignment | ||
Range on Protein: 640-760
Range on HMM: 27-145/310.0
GALLAQYELMYRKNpDLAITEARKPANAPKNRYRDISPYDCTRVSLV--NSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLL
| || . |. | ..| . |||| |. | .|| | .| .||| ||||. . . .| .|||| | |||||. || . .
eglvkqyrkldakq.dssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktny...lrstficsqgplqhtiidfwrmifqeraesi
VMLTTVMESGRQKCHQYWPVTGE
..| |.| || || ||| |
lllckvgeegrpkcvgywpslgv
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 665-824 | 5.6e-22 | 72.8 | In-house | 49-208 (301) | alignment | ||
Range on Protein: 665-824
Range on HMM: 49-208/301.0
ANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQL
. |.|| . | | ... . | ||... . | .|.||||||| .|. ||| |..| . .|||. .| .||..| ||. .|
lpkdkhryptvPckPstavevivdGkrvPihanwipts...GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekld
AEGFSVRCLSEKPDETGSFVFREFVLKD---KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTE
. |... ... . . |.. ..| | . | . | || |.|. || .. |
igrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlme
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 653-828 | 7.2e-22 | 72.3 | In-house | 31-163 (392) | alignment | ||
Range on Protein: 653-828
Range on HMM: 31-163/392.0
NPDLA-ITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGr
.||. | |.|. | .||||..| ||| .|| | .. ||.|| |.. . . |||.||| |.. |||||| || ..|.| . |
gpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsf...dnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.
qkchqywpvtgeelqlaegfsvrclsekpdetgsfvfrefvlkDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
...| . .. |||. || . .|.| . |.|
...........................................kgddartvaqfhftewPdkdvpkhtssllkfikevka
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 795-953 | 1.3e-21 | 72.2 | In-house | 45-139 (144) | alignment | ||
Range on Protein: 795-953
Range on HMM: 45-139/144.0
EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAArnrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPP
. |.... ..| ||||.||....|.||| | ...| . . |
leregiqylhlpwpDhgvpdllellleflefieea...........................................................leeggp
VIVHCSAGIGRTGVLILMDtalaLMEAREpVYPLDIVRTMRDQRACMVQNVSQYRFVCE
|.||||||.||||.|.... || . . . .... .| .| ..|.| .|.||..|
vlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 662-827 | 2.1e-21 | 71.1 | In-house | 31-197 (285) | alignment | ||
Range on Protein: 662-827
Range on HMM: 31-197/285.0
RKPANAPKNRYRDISPYDCTRVSLVNSlTGDYINANYvnMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEE
|| ||| |. . ||| | | ||| |.. | .|| . ||.||||| | .|||.|. || ..|| |..| | .|| |.| |
ayeanpdlnryadvrcieetrvvlknh.drdyihasw..mrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
LQLAEGFSVRCLSEKPDETGSFVFREFVLKD----KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVR
. . . | . .. . . . | .. |.| |||. | | ..|. . |.
vvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvk
|
|||||||||
FERM_M | FERM central domain | 123-232 | 2.5e-21 | 66.3 | Pfam-A | 1-126 (126) | alignment | ||
Range on Protein: 123-232
Range on HMM: 1-126/126.0
DPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFN-ALEHQPGY-LSGMQL------LC--------DQTTEAERKVGELHKLHR
||.....| .....|.|.|...|...|.|. .. |||.. .| |.||.. . ... .. .. .. | .. . |... | || ..
dpnpkydevrinllYeQakwdlleerldcteeeallLAALqlqiekgdseeeekasssdlekeeeeaeseqllpvsprllkkekskqleqrileahknva
GQLPADAEYNYLEHAKRLELYGIDLH
|. .|.|...||. |..|. ||..|.
glslaeaklkylqaaqslpdyGvslF
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 690-832 | 3.8e-21 | 71.1 | In-house | 11-108 (176) | alignment | ||
Range on Protein: 690-832
Range on HMM: 11-108/176.0
TGDYINANYVNMEipggavnRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVtG-EELQlaegfsvrclsekpdetgsfvfref
||||||.. . |.||||||| .|. ||..|.... ...|.||. .| || ||..|||. ..
dldyinanlilgs.......rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe.leklgi.........................
vlkdkheqrhihHMQYLAWPDHCVPSDpNLFLEFTERVRAARNR
. ..| ||||.||.. .|.||. | .| |...
............qylhlpwpDhgvpdl.elllellefirealke
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 884-961 | 6.7e-21 | 69.6 | In-house | 208-287 (293) | alignment | ||
Range on Protein: 884-961
Range on HMM: 208-287/293.0
VHQCI--SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
|.. | .|.. |..||||||.||||..| .|. | .| .. | . || .| .|...||...|| |. .|. . .|
vreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
FERM_N | FERM N-terminal domain | 38-121 | 1.6e-20 | 63.2 | Pfam-A | 1-80 (80) | alignment | ||
Range on Protein: 38-121
Range on HMM: 1-80/80.0
VLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWVDAQKQFKKQCSSvsldNDAVPLLEFRVKFFV
| .||. .... ......|..||..|.. |.|.| .|||| | .. . .|.|..|. ..|... ... .| .||||.|
VrlLDgtvkevtvddsktgavlletVckrlglteteyFgLafkedkknesnwLdhdktlreqgve....egkpttlllrvkfyv
|
|||||||||
subfamily_egg_pd | Subfamily egg | 656-804 | 4.9e-20 | 66.4 | In-house | 30-179 (307) | alignment | ||
Range on Protein: 656-804
Range on HMM: 30-179/307.0
LAITEARKPANAPKNRYRDISPYDCTRVSLV---NSLTGDYINANYVNmeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESgrQKCH
..|.| . | | | . . | .|| | ..|.| ||.|. . .| .| .| || | |||||| || . .||||. || ..|.
islttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvk...Gkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erce
QYWPVTGEELQLA--EGFSVRCLSEKPDETGSFVF-REFVLKDKHEQRHIHHMQY
||| . .. .. . .| . | . .. ..|.|.. | |.
yywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg
|
|||||||||
FA | FERM adjacent (FA) | 327-371 | 6.1e-20 | 59.8 | Pfam-A | 1-43 (47) | alignment | ||
Range on Protein: 327-371
Range on HMM: 1-43/47.0
SRFLniSLGSKFYYSGRTELQAVQESKQRGRIHKVFVRSPSKRLL
|.|. |||||| ||||||.|...||...|| .. | |||||| |
skff..slGSkFRYSGRTekQvieesreigrkppsfeRspskryl
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 889-963 | 1.4e-19 | 65.2 | In-house | 226-299 (300) | alignment | ||
Range on Protein: 889-963
Range on HMM: 226-299/300.0
SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICaAYMKIS
..|||.||||||.|||||||| | .| .| | . .....| || .||...||.|| . . |.| |
keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvli.kylkns
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 890-956 | 1.4e-19 | 65.1 | In-house | 196-261 (270) | alignment | ||
Range on Protein: 890-956
Range on HMM: 196-261/270.0
AANpPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
|. |..||||||.||||.||..|.|. |.| .. | .| |.. .| .| .|| . ||.|. . .
kae.PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 881-962 | 1.7e-19 | 66.0 | In-house | 140-228 (272) | alignment | ||
Range on Protein: 881-962
Range on HMM: 140-228/272.0
STSVHQCISAaNPPVIVHCSAGIGRTGVLILMDTALALMEAREPVY--------PLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKI
.. . . . . ||.||||||..|||...... |. ... | ....|. .|.||...||. ||.|..|.. ......
llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 888-957 | 2.2e-19 | 64.8 | In-house | 198-267 (273) | alignment | ||
Range on Protein: 888-957
Range on HMM: 198-267/273.0
ISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
. . |..|||||||||.|.|| .|..| |.| ... .|||..|.|| .|| || || . |
lqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 665-830 | 4e-19 | 63.7 | In-house | 42-204 (288) | alignment | ||
Range on Protein: 665-830
Range on HMM: 42-204/288.0
ANAPKNRYRDISPYDCTRVSLVNSlTGDYINANYVNmeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV-TGEELQ
||. ..||... | ||| | . . ||.|| | . .| | .| || .| .|.|. .. . .|||. ..| |..| .|.|. ||. .
anptrdryenlprcditrvklsdd.pdfyiaanvvs...sakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
LAEGfsVRCLSEKPDETGSFVFREFVLKDKHEQRH--IHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
. .| .. | . |. . . . .. .| |.|..|| . .| . |.... .
igrl..ctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslq
|
|||||||||
PDZ | PDZ domain (Also known as DHR or GLGF) | 505-588 | 5.5e-19 | 58.3 | Pfam-A | 2-80 (81) | alignment | ||
Range on Protein: 505-588
Range on HMM: 2-80/81.0
IRLQADEQGRYGFNVKGGVDLS-LPVQVSKVVPHtPADRCTPrVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHqasgELLLTV
..|.....|. ||..||| | . .. ||.||| .|. . . ..||| .| .||.|| ...|...|..|.... |. ||.
vslekekrgglGfslkggsdkrdkgifvsevvpg.gaaeadg.lkeGDkIlsvNgvdvenvshdeavqaikgkkg....evtLti
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 883-956 | 2.4e-18 | 62.0 | In-house | 101-170 (176) | alignment | ||
Range on Protein: 883-956
Range on HMM: 101-170/176.0
SVHQCISAaNPPVIVHCSAGIGRTGVLILMDtalaLMEAREPVYPLDIVRTMRDQRA-CMVQNVSQYRFVCECIC
....... . ||.|||||||||||.|.... |.| . . ........|.|| ..||. .||||. |...
firealke.ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefel
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 883-958 | 3.7e-18 | 60.5 | In-house | 205-280 (564) | alignment | ||
Range on Protein: 883-958
Range on HMM: 205-280/564.0
SVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
|... . . |..||||||.||||. | .| | ... . | .|...| || |||. .|| |. | | |
kvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailea
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 885-958 | 1.4e-17 | 58.5 | In-house | 200-276 (290) | alignment | ||
Range on Protein: 885-958
Range on HMM: 200-276/290.0
HQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREP---VYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
.. .. . |..||||||.||||..| .| . |..|. . |.|...| |||..|| ||..| ...
relqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 884-957 | 1.7e-17 | 58.4 | In-house | 204-277 (288) | alignment | ||
Range on Protein: 884-957
Range on HMM: 204-277/288.0
VHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
|.. .| |.|||||||.||||. | .|... .|. . . ...| .| ||| .||...|| |. |..
vkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 889-959 | 2e-17 | 58.3 | In-house | 204-276 (281) | alignment | ||
Range on Protein: 889-959
Range on HMM: 204-276/281.0
S-AANPPVIVHCSAGIGRTGVLILMDTALALMEA-REPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAY
. . |...|||||.||||. | .|... .|| .|.. . ..|. .| .| ||| | ||.|| . |
ekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 884-952 | 2.7e-17 | 58.3 | In-house | 81-143 (152) | alignment | ||
Range on Protein: 884-952
Range on HMM: 81-143/152.0
VHQCISAANPPVIVHCSAGIGRTGVLILMDTALalmearEPVYPLDIVRTMRDQRACMVQNVSQYRFVC
..... . ||.||||||.||||.|.... | | ....|. .| .| ..|.| .|.||.
ieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 709-828 | 3.1e-17 | 58.1 | In-house | 9-83 (152) | alignment | ||
Range on Protein: 709-828
Range on HMM: 9-83/152.0
NRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWpvtgeelqlaegfsvrclsekpdetgsfvfrefvlkdkheqrhihHMQYLAWP
...||||||. |. |||||... . .||||. .| |. ||.||. . ..| ||
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................qylhlpwp
DHCVPSDPNLFLEFTERVRA
||.||... |.|.. . ..
Dhgvpdlsqlllflllfiek
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 883-965 | 3.4e-17 | 57.4 | In-house | 218-302 (306) | alignment | ||
Range on Protein: 883-965
Range on HMM: 218-302/306.0
SVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDI---VRTMRDQRACMVQNVSQYRFVCECIcAAYMKISRS
... .| . |..||||||||||| .|..|. | |.| . ...|| |...|.|| .|| .||.|| . | ..|.. ...
kqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykai.kkyietkkk
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 687-828 | 4e-17 | 57.3 | In-house | 42-189 (290) | alignment | ||
Range on Protein: 687-828
Range on HMM: 42-189/290.0
NSLTGDYINANYVNMeiPGGavNRYIATQGPLA-------STTTDFWRMVQQESSHLLVMLTTVMESGRQ----KCHQYWPVT-GEELQLaEGFSVRCLS
. .. ||| ||.| . | | | |.|| |.. || .|| |..|| .. .||| ..| .. | .| | . ||||.. .|..|.| |
krfnddyiHAnrvtc..png..lrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkf.kgltvkCks
EKPDEtgSFVFREFVLK-DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
.. . || |.| |..|. . | .. | . |. |. ..|. . |.|
keked..dvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvka
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 886-959 | 5.2e-17 | 56.7 | In-house | 222-295 (330) | alignment | ||
Range on Protein: 886-959
Range on HMM: 222-295/330.0
QCISA-ANpPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAY
.. |. |..||||||.|||| .| .|. |. ..| . | ..|. .| ||. ||| || |. . . |
klnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 889-958 | 8e-17 | 56.3 | In-house | 210-279 (318) | alignment | ||
Range on Protein: 889-958
Range on HMM: 210-279/318.0
SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
.. . |..||||||.||||| | .|. | ..| . | ...|...|.|| ||| .|| |. . . |
ksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllea
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 889-955 | 1.3e-16 | 55.5 | In-house | 220-286 (297) | alignment | ||
Range on Protein: 889-955
Range on HMM: 220-286/297.0
SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
. .||..||||||||||| .| .| .|. .| . | . |...| ||| ..| || | ..
hpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 891-958 | 1.4e-16 | 55.5 | In-house | 215-282 (319) | alignment | ||
Range on Protein: 891-958
Range on HMM: 215-282/319.0
ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
. |..||||||.|||| | .| .| .. . . .|...| || .|||. .||.|. | . .|
qsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyeallea
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 888-958 | 3.5e-16 | 54.2 | In-house | 212-283 (297) | alignment | ||
Range on Protein: 888-958
Range on HMM: 212-283/297.0
ISAANP-PVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
| . |..|||.||.||||||. .| .| .. . | ...|. .|..| .|| ||.|| . . |
fsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlea
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 892-957 | 2.3e-15 | 51.7 | In-house | 224-289 (319) | alignment | ||
Range on Protein: 892-957
Range on HMM: 224-289/319.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
. ...||||||.||||| | .|. | |. . | ..|| .|.|| .||.. || |. .
ranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 892-955 | 3.1e-15 | 51.1 | In-house | 216-279 (305) | alignment | ||
Range on Protein: 892-955
Range on HMM: 216-279/305.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
. |..||||||.||||| | .| || ... | | ......| .| |||. || |. . .
gvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdal
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 892-958 | 3.6e-15 | 51.2 | In-house | 188-254 (284) | alignment | ||
Range on Protein: 892-958
Range on HMM: 188-254/284.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
. ...||||||.||||| | .|. | |. . | ..|| .|.|| .||.. || |. .
ranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysallee
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 882-961 | 5.2e-15 | 50.4 | In-house | 208-290 (325) | alignment | ||
Range on Protein: 882-961
Range on HMM: 208-290/325.0
TSVHQCISA---ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
|.... | | |..||||||.|||||.| . .||| . | .. |. .| .| ||. | || .. |.. |||
kavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 871-957 | 7.8e-15 | 49.1 | In-house | 196-285 (563) | alignment | ||
Range on Protein: 871-957
Range on HMM: 196-285/563.0
GATPEDETPVSTSVHQCISAANP---PVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
..|| ..|| . |.. | . |..||||||.||||..| .|| | ..... | .......| || .||. || |. . .
hgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalle
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 885-960 | 1.9e-14 | 48.5 | In-house | 212-287 (307) | alignment | ||
Range on Protein: 885-960
Range on HMM: 212-287/307.0
HQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYM
.. . . |..|||||| ||.|... .| | ..| . | ..|. .| || .||. || |. . .
relyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 665-798 | 2e-14 | 48.3 | In-house | 32-156 (267) | alignment | ||
Range on Protein: 665-798
Range on HMM: 32-156/267.0
ANAPKNRYRDISPYDCTRVSLVNSlTGDYINANYVNMEIPGgavNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVmesGRQKCHQYWPVTGEELQL
|. .||. | ||| ||| | .. . .|||| ||. . | .|.||.|| | |||. ..... |.||.| . .. ...|| . .
knqernrlddnlpyddtrvilrtk.eeeyinasyvegyktk...nafivtqdplkntitdfltvihdqkvpvivlltkv...ftdnirlfwPPkmgqakk
AEGFSVRCLSEKPDETGSFVFREfvLKDKHEQRH
. ..| || .. . | || | | |
yqdltvehslekeendyqiitle..lkfknesah
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 893-960 | 2.2e-14 | 47.9 | In-house | 211-278 (287) | alignment | ||
Range on Protein: 893-960
Range on HMM: 211-278/287.0
PPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYM
|..||...||||.|.|. . . . .| | . .| .| .||..|| | |.|...| . . |
GPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 890-958 | 3.5e-14 | 47.3 | In-house | 208-276 (314) | alignment | ||
Range on Protein: 890-958
Range on HMM: 208-276/314.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
. ...|||||| ||||. | .|. | ..| .. | .|.|.|... ||. ||.|. . | |
eeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvilea
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 887-966 | 5.9e-14 | 46.5 | In-house | 196-278 (290) | alignment | ||
Range on Protein: 887-966
Range on HMM: 196-278/290.0
CISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVR---TMRDQRACMVQNVSQYRFVCECICAAYMKISRSS
..| |...||||||||.| ..|.|| |.|.|... . .|| . .| .| ..| | || | .| ..|
slssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgds
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 667-755 | 7.5e-14 | 45.8 | In-house | 49-153 (349) | alignment | ||
Range on Protein: 667-755
Range on HMM: 49-153/349.0
APKNRYRDISPYDCTRVSLVNSL-----------------TGDYINANYVNMEIPgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQ
||||.|| ||. .|| | .|| |||||||... . ..||||| || || ||.... . .|.. |. | . .
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltri.svekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
KCHQYW
||..||
kcdiyw
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 890-960 | 8.3e-14 | 46.1 | In-house | 214-284 (290) | alignment | ||
Range on Protein: 890-960
Range on HMM: 214-284/290.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYM
| ...||||...||..|.. ..|.. .. . .......| |. .|| | ||..... . .
rgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 653-757 | 8.4e-14 | 45.8 | In-house | 84-180 (244) | alignment | ||
Range on Protein: 653-757
Range on HMM: 84-180/244.0
NPDlAITEARKPANAPKNRYRDISPYDCTRVSLVN-SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESgrqkc
.| . .| .| |. ||| |.| || | . |. |||| .| | || || ||| |. |||.|. . .||.| .| |
dps.vmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfvgcl...grtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....
HQYWPV
.|||
deywpd
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 890-957 | 1e-13 | 45.8 | In-house | 210-278 (288) | alignment | ||
Range on Protein: 890-957
Range on HMM: 210-278/288.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYP-LDIVRTMRDQRACMVQNVSQYRFVCECICA
.. |..||||||.|||||. |. .|.. .|... . ...|...| || |||...|..|. | .
ksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavle
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 670-815 | 1.2e-13 | 45.4 | In-house | 47-194 (312) | alignment | ||
Range on Protein: 670-815
Range on HMM: 47-194/312.0
NRYRDISPYDCTRVSLVNSlTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQL--AEG
||| .| .| | .| || ||.|.. .|...||||| .|.| ||... .| ...|....| | .|| .| ..|
nrypniqcwdrgrftlagd.enfyihanfvkict...kperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrv
FSVRCL----SEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSD
.. | | . . |.| .. .. | |. .|||| .|
yteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpds
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 892-956 | 1.7e-13 | 45.1 | In-house | 210-274 (315) | alignment | ||
Range on Protein: 892-956
Range on HMM: 210-274/315.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
. ...||||||.|||||.| .| .| .. .. | ...|...|..| .|| .| |. . .
efsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavl
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 893-956 | 2.4e-13 | 44.3 | In-house | 213-276 (439) | alignment | ||
Range on Protein: 893-956
Range on HMM: 213-276/439.0
PPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
||.||||||.|||| .| .| || . . . | ||. .|.|| |||.. || |. ...
gpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavl
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 889-958 | 3.1e-13 | 44.6 | In-house | 220-289 (298) | alignment | ||
Range on Protein: 889-958
Range on HMM: 220-289/298.0
SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
| | ||||.||||.||.| | .|. | ... . | ...|...| .|. .|| .|| |. | . |
qagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlea
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 892-955 | 3.2e-13 | 43.6 | In-house | 209-272 (515) | alignment | ||
Range on Protein: 892-955
Range on HMM: 209-272/515.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
. |.|.|||||.|||||.| .| .| .. . | ...|. .|..| .|| || |. . .
thpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygav
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 885-959 | 3.8e-13 | 44.0 | In-house | 205-279 (315) | alignment | ||
Range on Protein: 885-959
Range on HMM: 205-279/315.0
HQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAY
.| .. ...||||||.|||| .| .|. | .|| . . .... .|..| ||| . ||.|. . . ..
kqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 891-955 | 4.7e-13 | 43.7 | In-house | 198-262 (283) | alignment | ||
Range on Protein: 891-955
Range on HMM: 198-262/283.0
ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
. |..||||.|||||.|.| . ... . . | .|. || || .||. ||..| | .
kkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 892-961 | 5.4e-13 | 43.2 | In-house | 223-292 (296) | alignment | ||
Range on Protein: 892-961
Range on HMM: 223-292/296.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
. ||.|..| | .|.|| . .| .| |.| | | . |.|.| .| .|.|| .|... . . |..
egPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlc
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 890-958 | 9.5e-13 | 42.9 | In-house | 173-241 (250) | alignment | ||
Range on Protein: 890-958
Range on HMM: 173-241/250.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
| | ||||.||||.||.| | .|. | .. . | ......| .| .|. .|| || | | |
agnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 885-959 | 1.3e-12 | 42.0 | In-house | 214-289 (305) | alignment | ||
Range on Protein: 885-959
Range on HMM: 214-289/305.0
HQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPL-DIVRTMRDQRACMVQNVSQYRFVCECICAAY
.| .. |..||||||||||| .. .. | . |. |. ..|...||||| .|| || |. . .
lsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 659-816 | 1.5e-12 | 41.7 | In-house | 40-190 (303) | alignment | ||
Range on Protein: 659-816
Range on HMM: 40-190/303.0
TEARKPANAPKNRYRDISPYDCTRVSLVNSltgDYINANYVNMEipggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVT
. . | |||. |. | ..| | .| || |.|.... . .. | || ||. |..|||.|. .. . ...| | | . . .|
sknqfvknmdknrfvdvicldhskvklsds...syihasyleld....sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn
GEELQLAEGfSVRCLSEKPDET-GSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDP
. |.. | |.| | | .|.. . . . . .| .| ||| .|||
qdflkfeer.sirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdg
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 890-957 | 1.5e-12 | 42.1 | In-house | 209-276 (287) | alignment | ||
Range on Protein: 890-957
Range on HMM: 209-276/287.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
.| ...||||...||..... ..|.. . . ..... .| |. .|| |.||.|... . .
rgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 884-956 | 1.7e-12 | 41.6 | In-house | 216-289 (297) | alignment | ||
Range on Protein: 884-956
Range on HMM: 216-289/297.0
VHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEarEPVYPLDIVRT---MRDQRACMVQNVSQYRFVCECIC
| .. |..||||.| ||||| ||.| |. . | .||. | .||||. .|. .|..|. ...
vnksyrGrscpivvhcsdGaGrtGvyilidlvlnrll..kGvkeidiaatlehlrdqrpglvktkdqfefaltava
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 887-957 | 2.7e-12 | 41.3 | In-house | 187-257 (267) | alignment | ||
Range on Protein: 887-957
Range on HMM: 187-257/267.0
CISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
. .|.|..|.||.|.||.| .. .|. | . . . | .| .|.|| .|. .| .. | ..
qlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 891-955 | 3.1e-12 | 41.0 | In-house | 227-291 (297) | alignment | ||
Range on Protein: 891-955
Range on HMM: 227-291/297.0
ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
| ...||||||.||.||..| |. || . . |.. .|.||| .|| . |. .. . .
rnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydav
|
|||||||||
subfamily_eak_pd | Subfamily eak | 652-816 | 7.2e-12 | 39.3 | In-house | 38-198 (332) | alignment | ||
Range on Protein: 652-816
Range on HMM: 38-198/332.0
KNPDLAITEARKPANAPKNrYRDISPYDCTRVSLVNSLTG--DYINANYvnMEIPGgAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQ
... |.|.|... . .| .| ||| | | .| |||| .| . ..|| | . . ||.|| .. | .|.| .| . .
yqrllsisetarleavnrn.vvkivpydrylvrltssqlnrlGyinasl..aefse.vGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkle
KCHQYWPVTG-EELQLAeGFSVRCLSEkpDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDP
| .|.| . |||. . | . . . . . .| ..|. | ...| .. | . .|
ksdkyfpdktreelkfG.ildverkef..vkrniletrllelskGnethrvlhykvfGwtettlpkye
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 888-955 | 7.7e-12 | 39.4 | In-house | 212-279 (290) | alignment | ||
Range on Protein: 888-955
Range on HMM: 212-279/290.0
ISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
. |. ||.||||||||||| .. ....| .. . .||.||..|. |. || || . | .
lrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveil
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 889-958 | 2.2e-11 | 37.8 | In-house | 124-193 (440) | alignment | ||
Range on Protein: 889-958
Range on HMM: 124-193/440.0
SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
|.| |..|||||| |||||.| .|. | . . . . .. .||..| ||| || || |.. .
kagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavleg
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 889-956 | 2.9e-11 | 37.7 | In-house | 259-341 (350) | alignment | ||
Range on Protein: 889-956
Range on HMM: 259-341/350.0
SAANPPVIVHCSAGIGRTGVLILMDTALA----LMEAREPVYPL-----------DIVRTMRDQRACMVQNVSQYRFVCECIC
.| .|..||||||.||||.|. .| | | . .. | || .| || ||||. |. |. |..
narsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 721-829 | 3.4e-11 | 37.7 | In-house | 40-148 (255) | alignment | ||
Range on Protein: 721-829
Range on HMM: 40-148/255.0
TTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFL
| |.....| .. .|||. | |..||..|.|. .| . . .| . | . | .| . . ..| .| |... | ... |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
EFTERVRAA
. || .
nilkvvrds
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 894-955 | 2.1e-10 | 34.6 | In-house | 171-232 (392) | alignment | ||
Range on Protein: 894-955
Range on HMM: 171-232/392.0
PVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
|.|.|||||.|||||.| .|. .| . | ...| .| .| ||| || |. ..
pliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygav
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 709-823 | 2.2e-10 | 35.1 | In-house | 4-119 (198) | alignment | ||
Range on Protein: 709-823
Range on HMM: 4-119/198.0
NRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSV--RCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLA
|||||| || | .|||.|| . | .||. |||.| .|| .... ||| | . . | | | |. .
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHCVPSdPNLFLEFT
| .. | ||. |
wkekttpn.valfvgfv
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 709-823 | 2.4e-10 | 34.9 | In-house | 5-120 (199) | alignment | ||
Range on Protein: 709-823
Range on HMM: 5-120/199.0
NRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSV--RCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLA
|||||| || | .|||.|| . | .||. |||.| .|| .... ||| | . . | | | |. .
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHCVPSdPNLFLEFT
| .. | ||. |
wkekttpn.valfvgfv
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 713-829 | 2.5e-10 | 34.7 | In-house | 42-154 (263) | alignment | ||
Range on Protein: 713-829
Range on HMM: 42-154/263.0
AtqgpLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDET-GSFVFREFVLKdKHEQRHIHHMQYLAWPDHC
| | |.....| .. .|||. | |..|| .|.|. .| | . .| . . | . .. . . . | . . ..| .| |...
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.KkkthtvkhysykgWiekn
VPSDPNLFLEFTERVRAA
| ... |. . .|
dpelareilnilkvarns
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 891-952 | 3.2e-10 | 34.6 | In-house | 173-233 (239) | alignment | ||
Range on Protein: 891-952
Range on HMM: 173-233/239.0
ANpPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVC
| | ..|||||.|||| ....|. | . .. | .. |...|..| ||| || |.
ar.pwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 884-961 | 3.3e-10 | 33.9 | In-house | 210-286 (302) | alignment | ||
Range on Protein: 884-961
Range on HMM: 210-286/302.0
VHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIcAAYMK
|.. . |. .... |.|| |... . .|. ... . . .||...| ||...|....|| .. .. . |.|
vfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyial.llyik
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 891-952 | 4.3e-10 | 34.2 | In-house | 174-234 (239) | alignment | ||
Range on Protein: 891-952
Range on HMM: 174-234/239.0
ANpPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVC
| | ..|||||.|||| ....|. | . .. | .. |...|..| ||| || |.
ar.pwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 890-957 | 5.7e-10 | 33.4 | In-house | 207-274 (312) | alignment | ||
Range on Protein: 890-957
Range on HMM: 207-274/312.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
. ||| |||||.|||| |.|... .| . |. .| .|| |. . || .. |.
kdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvle
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 883-963 | 7e-10 | 33.1 | In-house | 217-296 (301) | alignment | ||
Range on Protein: 883-963
Range on HMM: 217-296/301.0
SVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIcAAYMKIS
.|. . ||.||||....|.|| . .. .| | | ......| .. .|. || .. . | |...
vihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvi.dmylqln
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 661-716 | 1.4e-09 | 32.0 | In-house | 43-95 (95) | alignment | ||
Range on Protein: 661-716
Range on HMM: 43-95/95.0
ARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEipgGAVNRYIATQG
|| ||||. .| |||.||| | ||||| .|. | |||.||
gsseanipknrflnifpydatrvvlttkrdsdyinacfvdgy...arkncyiaaqg
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 874-952 | 1.5e-09 | 32.2 | In-house | 183-263 (285) | alignment | ||
Range on Protein: 874-952
Range on HMM: 183-263/285.0
PEDETPVSTsVHQCI---SAANPPVIVHCSAGIGRTGVLILMDTALA-LMEaREPVYPLDIVRTMRDQRACMVQNVSQYRFVC
||| |. ... . . |. ||||||.||| .. .| | .|| . ||||| || | ||. |. |.
pedarpmie.lykwvkkvnpkekpicvhcsagvgrtatfvgidyatirime.npniemldivremramrfqavqshmqflfly
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 884-961 | 1.6e-09 | 31.7 | In-house | 214-290 (302) | alignment | ||
Range on Protein: 884-961
Range on HMM: 214-290/302.0
VHQCISAaNPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMK
.. | | |.||||||.|||| |. . . | .. |.|| .|. | ||. .| .. |. . |.
lkfcesy.kknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkglme
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 890-956 | 1.9e-09 | 31.3 | In-house | 263-341 (349) | alignment | ||
Range on Protein: 890-956
Range on HMM: 263-341/349.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEARE-PVY-------PLD----IVRTMRDQRACMVQNVSQYRFVCECIC
. ....|||||| ||||||. .| |...| . | || ..| || ||||..|. .. |..
dqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealL
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 891-957 | 2.2e-09 | 31.5 | In-house | 218-285 (305) | alignment | ||
Range on Protein: 891-957
Range on HMM: 218-285/305.0
ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPL-DIVRTMRDQRACMVQNVSQYRFVCECICA
. |..||||||||||| ..... | . | . . |.. .|.|| .| || || . |
skgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 892-955 | 2.5e-09 | 31.7 | In-house | 172-235 (237) | alignment | ||
Range on Protein: 892-955
Range on HMM: 172-235/237.0
NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
| |.|||||.||||.....|. | . .. | . | .. ..| ..| || |. . |
sgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 709-810 | 5.9e-09 | 29.7 | In-house | 236-331 (440) | alignment | ||
Range on Protein: 709-810
Range on HMM: 236-331/440.0
NRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMEsgrQKCHQYWPVTGEELQLAeGFSVrclSEKPDE-TGSFVFREFVLKDKHEQRHIHHMQYLAW
| .|||| || || ||||.|.. ..|| . . . | |||| . . |.| | | | . || | | | .. .|
nafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfg.pftv...ghkgsenmnrvkvrtlelkykeevheirqfevqtw
PDH
|
ptw
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 879-962 | 8.7e-09 | 29.9 | In-house | 178-262 (290) | alignment | ||
Range on Protein: 879-962
Range on HMM: 178-262/290.0
PVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALME-AREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKI
. .|. | . | . |||||| || | .| .. . .. .. | |.. ..| ||| .... .. || | ...
ktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaiev
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 890-955 | 1e-08 | 29.5 | In-house | 207-273 (307) | alignment | ||
Range on Protein: 890-955
Range on HMM: 207-273/307.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYP-LDIVRTMRDQRACMVQNVSQYRFVCECI
. ||.||||||.||.| .. . | | . ..|. .|.|| .|. || .. .
ydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvl
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 677-757 | 2.1e-08 | 28.5 | In-house | 4-71 (130) | alignment | ||
Range on Protein: 677-757
Range on HMM: 4-71/130.0
PYDCTRVSlvnslTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESgrqkcHQYWPV
... .|. .||||..| . | . |. || ||| |..|||.|. . .||.| .| | .|||
efevsrlq.....gntyinasfvGll...grtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpd
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 889-952 | 4.2e-08 | 28.6 | In-house | 111-170 (194) | alignment | ||
Range on Protein: 889-952
Range on HMM: 111-170/194.0
SA-ANPPVIVHCSAGIGRTGVLIlmdtALALMEARePVYPLDIVRTMRDQRACMVQNVSQYRFVC
.. .. | ||| ||.||||.|. | .|.. . . . ....|. | ...|..... ..
nedpggvvaVHCkaGlgRtGtlv....aaYLiyrl.gmsaeeAialfrekRpgaipnqdyleall
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 886-956 | 4.5e-08 | 27.5 | In-house | 198-268 (288) | alignment | ||
Range on Protein: 886-956
Range on HMM: 198-268/288.0
QCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
. . . . |..||.|||.|||| |||. || . . . .. .|..| .| || .| |.
evlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvl
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 896-958 | 9.4e-08 | 26.4 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 896-958
Range on HMM: 2-64/69.0
IVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
.||||.| |||| .| . .| . . | .. |. || | || | .| |. . . |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 896-958 | 1.1e-07 | 26.1 | In-house | 1-63 (69) | alignment | ||
Range on Protein: 896-958
Range on HMM: 1-63/69.0
IVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
.||||.| |||| .| . .| . . | .. |. || | || | .| |. . . |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 890-951 | 1.6e-07 | 25.4 | In-house | 212-273 (301) | alignment | ||
Range on Protein: 890-951
Range on HMM: 212-273/301.0
AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFV
.. |..|||||||||. .| . .|| . . .. .|..| . ||..|| ..
ksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywm
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 716-822 | 6.3e-07 | 23.1 | In-house | 98-213 (302) | alignment | ||
Range on Protein: 716-822
Range on HMM: 98-213/302.0
GPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV-TGEELQLAEgFSVRCLSEKP------DETGSFVFrEFVLKD----KHEQRHIHHMQY
| ||. .| ...| . . | |....|.. .|| .|. |.||.. . ..|. .| | | . .. .|. |. .. .. ...
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgr.ytvktvsvktdleeftdkksfkly.tveiknekkkkkvkktvdilaf
LAWPDHCVPSDPNLFLEF
||||| | ... |.
sawpdhGapkeaytaldi
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 884-954 | 1.9e-06 | 21.7 | In-house | 192-264 (281) | alignment | ||
Range on Protein: 884-954
Range on HMM: 192-264/281.0
VHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPL-DIVRTMR-DQRACMVQNVSQYRFVCEC
. . | | | ..|||||.||.| |. .. || . .. . . .|| .| ||. || . || .. .
ilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkv
|
|||||||||
PTEN_1 | 873-938 | 2e-06 | 22.7 | In-house | 109-171 (196) | alignment | |||
Range on Protein: 873-938
Range on HMM: 109-171/196.0
TPEDETPVSTSVHQCISAANP--PVIVHCSAGIGRTGVLILMdtalALMEAREpVYPLDIVRTMRDQR
. . . |.......... |.||| ||.||.|... . ||... . . .. .|..|
slselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaa....yLmykgk.ltadeAlelvrekR
|
|||||||||
subfamily_egg_pd | Subfamily egg | 889-966 | 2.6e-06 | 21.3 | In-house | 198-277 (307) | alignment | ||
Range on Protein: 889-966
Range on HMM: 198-277/307.0
SAANPPVIVHCSAGIGRTGVLILMDTALALMeAREPVYPLDIVRT---MRDQRACMVQNVSQYRFVCECICAAYMKISRSS
. ||.|.. |. ....|. ...|| . | |.. . |. .| .| |. | .| || . . . |.
rnlskpvvvqdilGvskaatlvaieiallsl.lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigsa
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 894-953 | 3.3e-06 | 21.7 | In-house | 116-170 (182) | alignment | ||
Range on Protein: 894-953
Range on HMM: 116-170/182.0
PVIVHCSAGIGRTGVLIlmdtALALMEArEPVYPLDIVRTMRDQRACMVQNVSQYRFVCE
| ||| || ||||||| | |. | . . . . ....|..|. .| .| ..| |
kvavhChaGlGrtGvli....acylvya.krltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 666-731 | 3.8e-06 | 20.6 | In-house | 37-107 (347) | alignment | ||
Range on Protein: 666-731
Range on HMM: 37-107/347.0
NAPKNRYRDISPYDCTRVSLVNS-----LT---GDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQ
. ||| .| | ||| | . |||| ..... | . || || || .| |||.||.
slsknrskdvklidatrvvlspeksknsraddvetyinashikfd...naskeyiltqyplpdtvrdfwkmvsv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 665-764 | 6.3e-06 | 19.8 | In-house | 50-147 (302) | alignment | ||
Range on Protein: 665-764
Range on HMM: 50-147/302.0
ANAPKNRYRDISPYDCTRVSLVNsLTGDYINANYVnmEIPGGAvNRYIATQGPLASTT---TDFWRMVQQESSHLLVMLTTVMESGRqKCHQYWPVTGEE
.| ||. |. .| ..| | . .|.|| | |.| . | .| | ... .||||| ||. .|.| | . ....| . ..
knlkknqsedvpildsnlvklea.epdsyvnaskv..evPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgd
LQL
.
yke
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 883-953 | 8.1e-06 | 20.7 | Pfam-A | 65-129 (133) | alignment | ||
Range on Protein: 883-953
Range on HMM: 65-129/133.0
SVHQCiSAANPPVIVHCSAGIGRTGVLIL---MDT-ALALMEAREPVypldivrtmRDQRACMVQNVSQYRFVCE
.... . . |.||| ||| |.. ||. |.| | | || | | ...| ....|... | ..|
fieka.eqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefv.........kerrskispnagflrqLle
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 883-953 | 8.1e-06 | 20.7 | In-house | 65-129 (133) | alignment | ||
Range on Protein: 883-953
Range on HMM: 65-129/133.0
SVHQCiSAANPPVIVHCSAGIGRTGVLIL---MDT-ALALMEAREPVypldivrtmRDQRACMVQNVSQYRFVCE
.... . . |.||| ||| |.. ||. |.| | | || | | ...| ....|... | ..|
fieka.eqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefv.........kerrskispnagflrqLle
|