Gene CG10352 in Drosophila melanogaster

Synonym: Dmel\CG10352, Phos10352, Dmel_CG10352, CG10352

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP072_AA protein Get Run
DmelP072_AA_19-297 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 25-299 1e-94 308.0 In-house 2-276 (279) alignment 
Range on Protein: 25-299
Range on HMM: 2-276/279.0
VFCDCDGVVWYPLRdFIPGSAEALAHLAHLGKDVTFVTNNSISSVKEHIEKFEKQGHLKIDEHQIVHPAQTICDHLRSIKFEGLIYCLATSPFKEILVNA
|..|||||.|.  . .|||.||||..|..|||.|.||||||..| .|...||.| |. |..|..|...|..|.|.|.. |||. .|.|... .|| | .|
vlfDcDGVlWlget.aipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlgeeglkeeLkea

GFRLAQENGSGIITRLK-DLHEAIFSGESVDAVIIDVDFNLSAAKLMRAHFQLQNPKCLFLAGAADALIPFGK-GEIIGPGAFIDVVTQAVGRQPITLGK
|..|.... . . ..|. |..|...  ..|.||...|| .||.|||..|. .|..|..||||...|||.|. |   | |.|........|.||.|..|||
giellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkkevvipgaGslvaaieaasgrkplvlGK

PGEDLRKLLLERHREiPPSRVLFVGDSLASDIGFARASGYQTLLVLTGGTKLEDVQRLPIDHSQMPDYLADCLGQIA
| | | .||||...   |.|.|..||.|..|| |....|.||||||.| ||||||...  .....|||..|.|....
Pnelllelllekeei.dpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkeeklvPdyyldsladll
Chronophin_1 23-297 1.3e-45 146.9 In-house 2-254 (261) alignment 
Range on Protein: 23-297
Range on HMM: 2-254/261.0
DLVFCDCDGVVWYPlRDFIPGSAEALAHLAHLGKDVTFVTNNSISSVKEHIEKFEKQGHLKIDEHQIVHPAQTICDHLRSIKFEGLIYCLATSPFKEILV
.|| .|.|||..    . .|| ||... |.. || |.||||||..  .|  ..... |  .. . .|.  | .    ||. . .. .| | ..  .. | 
qlvLlDldGVlikg.eeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelr

NAGFRLAQENGSgiitrlkdlheaifsgeSVDAVIIDVDFNLSAAKLMRAHFQLQNPkCLFLAGAADALIPFGKGEIIGPGAFIDVVTQAVGRQPITLGK
.||.||..|.                   .|.||.. .| .|| .|| .|   .... .||.|  .|  .|  .| . | |. . .|. | ||.|.  ||
eaGlrlvdeped.................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeGiaPgtGslaaaveaAsgreplvvGK

PGEDLRKLLLErHREIPPSRVLFVGDSLASDIGFARASGYQTLLVLTGGTKLEDVQRLPidHSQMPDYLADCLGQ
|   . .  || .... |.... ||| |  || ... .|..||||||| ..||..|. .  ..  ||.... . .
Pepvmfeeale.kigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk..kdlrPdavvesiad
Chronophin_2 24-294 1.1e-40 130.7 In-house 2-272 (282) alignment 
Range on Protein: 24-294
Range on HMM: 2-272/282.0
LVFCDCDGVVWYPLRdFIPGSAEALAHLAHLGKDVTFVTNNSISSVKEHIEKFEKQGHLKIDEHQIVHPAQTICDHLRS-IKFEGLIYCLATSPFKEILV
 |. |||||.|   .  ..|..| . .||..||.| ||||||  . .....|| . |  .. . ||   |     .||   . .| .. . .  ... | 
nvlfdcdgviwngek.avagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadvrgkvfviggeglrkelr

NAGFRLAQENGSGIiTRLKDLHEAifsgESVDAVIIDVDFNLSAAKLMRAHFQLQNPKCLFLAGAADALIPFGKGEII-GPGAFIDVVTQAVGRQPITLG
.|| .....      . . |  ..      | ||..  | .|.  || .|   |....||.||   |   |. .|.|. | |..   .  | ||. . .|
eagvpvvedadeqe.asiydcald....pdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvig

KPGEDLRKLLLERHReIPPSRVLFVGDSLASDIGFARASGYQTLLVLTGGTKLEDVQRLPI-----DHSQMPDYLADC
|| . . . . .    . |.| |..|| | .|| |    | .|.| ||| ..||. |.        ... .|||. ..
kpsrfmfecissqfs.vdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvves
Hydrolase_6 Haloacid dehalogenase-like hydrolase 25-126 3.7e-24 76.0 Pfam-A 1-100 (101) alignment 
Range on Protein: 25-126
Range on HMM: 1-100/101.0
VFCDCDGVVWYpLRDFIPGSAEALAHLAHLGKDVTFVTNNSISSVKEHIEKFEKQGhLKIDEHQIVHPAQTICDHLRSIKFEGLIYCLATSPFKEILVNA
...|.|||.|   .. |||.||||  |   || | ..|||| .| .|...|.|| | ....|.|.|..|. . ..|...|........ . ...|.| .|
flfDvdGvLwr.gdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklg.vdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkea

GF
||
Gf
subfamily_LHPP_pd Subfamily LHPP 25-272 1.6e-21 68.3 In-house 1-221 (227) alignment 
Range on Protein: 25-272
Range on HMM: 1-221/227.0
VFCDCDGVVWYpLRDFIPGSAEALAHLAHLGKDVTFVTNNSISSVKEHIEKFEKQGhLKIDEHQIVHPAQTICDHLRSIKFEG--LIYCLATSPFKEILV
|. |  ||..      |||..|||..| . |. |.||||.. .| ..  |.  . | ....|..|. ... ... ||. | .   |.   . . |..|  
vllDlsGvlhn.edaaipgavealkrLrqagvkvrfvtNttkeskralverLirlg.fdveeeeiftsleaarqllrerklrpyllveddveedfedidt

NAGfrlaqengsgiitrlkdlheaifsgesvDAVII-DVDFNLSAAKLMRAHFQLQN-PKCLFLAGAADALIPFGKGEIIGPGAFIDVVTQAVGRQPITL
.                              .||.| ... ... ..| .|.  | . .|   .|   .      .| ..|||||.  .  |.| .   .
dkp............................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevv

GKPGEDLRKLLLERHrEIPPSRVLFVGDSLASDIGFARASGYQTLLVLTGGT
||| . . .  ||.  ...|.... .||.. .|.. | . | ...|| ||  
GKPsalffekaleel.gvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkf
Hydrolase_like HAD-hyrolase-like 220-293 3.3e-15 47.1 Pfam-A 2-70 (75) alignment 
Range on Protein: 220-293
Range on HMM: 2-70/75.0
LGKPGEDLRKLLLERHrEIPPSRVLFVGDSLASDIGFARASGYQTLLVLTGGTKLEDVQRLPIdhsqMPDYLAD
|||| . . .  ||.. ..|||.|. .|||||.|| .|.. | ...||||| .. || .. ..     ||| .|
lgKPnpgmydkalevl.gappsevvmiGDslatDieaAnnaGirsilVltGvsreedlklaka....kpdyvvd
HAD_2 Haloacid dehalogenase-like hydrolase 216-267 4.3e-06 18.4 Pfam-A 127-176 (176) alignment 
Range on Protein: 216-267
Range on HMM: 127-176/176.0
QPITLGKPGEDLRKLLLERHrEIPPSRVLFVGDSLaSDIGFARASGYQTLLV
. .   || ... . .|||. ...| ..||..||| .|.  ||| | .| .|
ddvgapKpdpeayekvlerl.gvkpeeilfidDsl.edveaAraaGirtvhv