Gene CG15739 in Drosophila melanogaster

Synonym: Dmel\CG15739, Phos15739, Dmel_CG15739, CG15739

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP074_AA protein Get Run
DmelP074_AA_22-301 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 25-300 4.9e-100 325.4 In-house 2-279 (279) alignment 
Range on Protein: 25-300
Range on HMM: 2-279/279.0
VVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGMQ-VHPEQIWHPAKSIVSYLQSIKFEGLIYIIASQSFKTVLREAG
|..|.|||||. |. ||.||. ..||...||...|.||||....|...| |.|.|.. |. |.|...|..|..||.. |||. .|.......|. |.|||
vlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlgeeglkeeLkeag

FQLLDGPNEFIEESYA-SLAEHIFGKEPVRAVIIDVDFNLTSPKILRAHLYLRHPECMLIEGATDRLLPVAKEVNIVGPGAFASILVEASGKQPITLGKP
..||....| ...... ...|... .. |.||...|| .|. .|.|.|. |||.||........|.|||..|||.|.|.|...... .|||..|..||||
iellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkkevvipgaGslvaaieaasgrkplvlGKP

GRELGDLLVEHYQIvQPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSGGCSKEELLAETDP-QRIPDYYADSVADVAQML
 ..| .||.|...| .|.|.|||||.|..|..||..||.|||||||| ...|.. ....  ...||||.||.||....|
nelllelllekeei.dpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkeeklvPdyyldsladllell
Chronophin_1 23-299 1.7e-51 166.2 In-house 2-258 (261) alignment 
Range on Protein: 23-299
Range on HMM: 2-258/261.0
DRVVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGMQ-VHPEQIWHPAKSIVSYLQSIKFEGLIYIIASQSFKTVLRE
. | .|.||||.  |. .| ||.  .||.| ||...|.||||.|| |. .. ....|.. |  |.|.  | .  ..|.. . .. .|.. ..  .. |||
qlvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelre

AGFQLLDGPNEfieesyaslaehifgkePVRAVIIDVDFNLTSPKILRAHLYLRHPeCMLIEGATDRLLPVAKEvNIVGPGAFASILVEASGKQPITLGK
||..| |.|..                  |.||.. .| .|.  |. .|  ..|.. ....    |.  | ..   . | |. | ..  |||..|.  ||
aGlrlvdeped.................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeG.iaPgtGslaaaveaAsgreplvvGK

PGRELGDLLVEHYQiVQPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSGGCSKEELLAETdPQRIPDYYADSVADVAQM
| . . .  .|. . ..|....|.|| |  |. .|...|..|||||.|  ..||. | .  .  ||....|.||... 
Pepvmfeealekig.adpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk.kdlrPdavvesiadllee
Chronophin_2 24-301 1e-50 163.6 In-house 2-281 (282) alignment 
Range on Protein: 24-301
Range on HMM: 2-281/282.0
RVVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGM-QVHPEQIWHPAKSIVSYLQ-SIKFEGLIYIIASQSFKTVLRE
 |. | |||.|  |. .. |..    | ..||.  |.|||| |. |. |. ||..|. .|. |||.  |     ||.   . .| ...| .. ..  |||
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadvrgkvfviggeglrkelre

AGFQLLDGPNEFIeesyASLAEHiFGKEPVRAVIIDVDFNLTSPKILRAHLYLRHPECMLIEGATDRLLPVAKEVNIVGPGAFASILVEASGKQPITLGK
|| .... ..|      ||. .    .  ||||..  | .||  |. .|  ||| ..|.|.   .|   |...   . | |.... |  |||.. . .||
agvpvvedadeqe....asiydc.aldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvigk

PGRELGDLLVEHYQiVQPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSGGCSKEELLAETD------PQRIPDYYADSVADVAQMLG
| | . . . .... |.|.| ||||| |  |. || .||..|.| |.|  | ||  . .|       . .|||. .|.||. . | 
psrfmfecissqfs.vdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesiadlleale
Hydrolase_6 Haloacid dehalogenase-like hydrolase 25-125 1.6e-29 93.2 Pfam-A 1-101 (101) alignment 
Range on Protein: 25-125
Range on HMM: 1-101/101.0
VVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGMQVHPEQIWHPAKSIVSYLQSIKFEGLIYIIASQSFKTVLREAGF
...|.||||| ... || ||.   ||...||.. .||||| ...|. .| . |.|..|..||....|.....||...|.......| .. .. .|.||||
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkeaGf

Q
.
k
subfamily_LHPP_pd Subfamily LHPP 25-271 7.5e-23 72.6 In-house 1-221 (227) alignment 
Range on Protein: 25-271
Range on HMM: 1-221/227.0
VVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGMQVHPEQIWHPAKSIVSYLQSIKFegLIYIIASQSFKTVLreAGF
|. |. |||.. ...||.|..  . | | |....|.||.. .. .. |.   ..|..|. |.|  ... ....|.. |     |.. ... .. .  ...
vllDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerkl..rpyllveddveedf..edi

QlLDGPnefieesyaslaehifgkepVRAVIIDVDFNLTSPKILRAHLYLRH-PECMLIEGATDRLLPVAKEvNIVGPGAFASILVEASGKQPITLGKPG
.  | |                       || ... ...  .. .|.  | . ..  ||   ...    ..   ..|||||.. | .| | .   .||| 
d.tdkp....................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdG.lalgpGafvkaleyatgvkaevvGKPs

RELGDLLVEHYqIVQPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSGGC
... .  .|.   |.|....|||| . .||    ..|....|| .|  
alffekaleel.gvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkf
Hydrolase_like HAD-hyrolase-like 220-295 1.9e-13 41.4 Pfam-A 3-74 (75) alignment 
Range on Protein: 220-295
Range on HMM: 3-74/75.0
GKPGRELGDLLVEHY--QivqPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSGGCSKEELLAetdPQRIPDYYADSVAD
||| ... |   | .      ||.|.|||| || |. .....| ...|||.|  ..|.| .   ... |||..|....
gKPnpgmydkalevlgap...psevvmiGDslatDieaAnnaGirsilVltGvsreedlkl...akakpdyvvddlee
Hydrolase haloacid dehalogenase-like hydrolase 25-260 1.1e-08 27.1 Pfam-A 4-215 (215) alignment 
Range on Protein: 25-260
Range on HMM: 4-215/215.0
VVSDIDGVLWTFEQSI--PRAADGYAALEQM--------GKHLTFLTNNSVRT-SeqCV--KLFAKIGMQVHPEQIwhpaksivsylqsikfegliyiIA
||.|..|.|.. |.|.  . ..   |.....        || ... . ..    .  .     |.. | . . . |                      ..
vvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstrgg..ltgfatfigrgvsgkvdgi......................vl

sqSFKTV-----------------LreagfqlldgpnefIE---------EsyaslaehifgkepvrAVIIDVDFNLT---SPKILRAHLYLRHP--ECM
  .                                     .                          ....  ..  .    |..  |  .|.    |  
..gnpewmtalglrviapdlvaaeg..............qskgrtvvvvav................qaralgviafadpvkpeaaeavasLkeaGievv

LIEGA-TDRLLPVAKEVNIVGPGAFASILveasgkqpitlGKPGRELGDLLVEHYQIvQPSRVLMIGDMLaQDVSFGRQCG
|. |   .    .||.. | .   ||              |||  .|  ...| .|| .|..|.|.|| .  |. .....|
lltgdnpetaeaiakqagiedslvfaevv...........gkPepklfvaaieeLqi.dpgevamvGDgv.nDapalaaAg
subfamily_CUT_pd Subfamily CUT 25-126 4.2e-07 19.8 In-house 21-125 (391) alignment 
Range on Protein: 25-126
Range on HMM: 21-125/391.0
VVSDIDGVLWTFEQSIPRAADGYAALEQMGK----HLTFLTNNSVRT-SEQCVKLFAKIGMQVHPEQIWH---PAKSIVSYlqsikFEGLIYIIASQSFK
.| ||||||   .. ||.| . .  ||.          ||||..  |  |.  || .|....| ..|.     | |... .     ..  .   . .| .
ivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkllaek.....ydkrllvvgqesvr

TVLREAGFQL
 |    ||. 
evaeglGfkn
Subfamily.CECR5.protein 25-126 4.5e-07 19.6 In-house 23-127 (393) alignment 
Range on Protein: 25-126
Range on HMM: 23-127/393.0
VVSDIDGVLWTFEQSIPRAADGYAALEQMGK----HLTFLTNNSVRT-SEQCVKLFAKIGMQVHPEQIWH---PAKSIVSYlqsikFEGLIYIIASQSFK
.| ||||||   .. ||.| . .  ||.          ||||..  |  |.  || .|....| ..|.     | |... .     ..  .   . .| .
ivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkllaek.....ydkrllvvgqesvr

TVLREAGFQL
 |    ||. 
evaeglGfkn
CECR5_TIGR01456 26-125 8.8e-06 15.3 In-house 42-144 (370) alignment 
Range on Protein: 26-125
Range on HMM: 42-144/370.0
VSDIDGVLWTFEQSIPRAADGYAALEQM-GK---HLTFLTNN-SVRTSEQCVKLFAKIGMQVHPEQIWH---PAKSIVSylqsiKFEGLIYIIASQSFKT
. ||||||   .. |. |.. .  | .  |.    . .|||   .  ...  .| |..|..| |.|.     | |..|      |.| .| .    . . 
aldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglseraraeelsalLgvevsplqviqshsPykklvn.....kyekrilasGkgevae

VLREAGFQ
| .. ||.
vaegyGFk