Gene CG32488 in Drosophila melanogaster

Synonym: CG2077, Dmel\CG32488, Phos32488, Dmel_CG32488, CG32488

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP077_AA protein Get Run
DmelP077_AA_24-305 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 27-305 5.8e-105 341.6 In-house 2-278 (279) alignment 
Range on Protein: 27-305
Range on HMM: 2-278/279.0
VILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKAKGFGIE-IKEDNVLTSSFSCANFLAVKNFQKKVFVMGEKGVHFELEKFG
|..|.|||||. ..||.||....|.....|.|.....|||  ||.|...|.| .|.| .||...|.|. ..|..|  |.|.|||.|.||.|.. ||.. |
vlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlgeeglkeeLkeag

ICSLKMSEKLEKPMHE--FVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMVGAGATLAAMKAYTGRSPLVLGKP
|..|..... .|....  ||.||.||.|||||.|| || ...|||... .|| .|.|.||.|. ||..|. ...|..|||...||..|..||.|||||||
iellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkkevvipgaGslvaaieaasgrkplvlGKP

NPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVGSGVNTPKEVQQIIEEGdpkkkILVPDTYLPSLGHMLEF
|......|...  |.|| |||.||.|.||..|..|||.|.|.|.|||.. ..|..| .|.      ||||.||.||...||.
nelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee.....klvPdyyldsladllel
Chronophin_2 26-305 2.4e-57 185.3 In-house 2-279 (282) alignment 
Range on Protein: 26-305
Range on HMM: 2-279/282.0
SVILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKAKGFGI-EIKEDNVLTSSFSCANFLA-VKNFQKKVFVMGEKGVHFELEK
.|..| |||.|   ||. ||..  . .  .|.......|||  .|.... |   .|. .........|.. .| .|  | . . ||||.| .|.. ||..
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadvrgkvfviggeglrkelre

FGICSLKMSEKLEkpmhEFVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMVGAGATLAAMKAYTGRSPLVLGKP
 |.  .. ... |      . .  ||||| ||.|| || . . || .. .|| ..| ..| |  |  .|. . |.. |.|.  ||... .||  .|.|||
agvpvvedadeqe....asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvigkp

NPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVGSGVNTPKEVQQIIEEGDPKKKILVPDTYLPSLGHMLEF
 ..|   . .   . |  .||.|| |.||. | ||||.....  .|| . .| |.  .   .... |||| .. |.  .|| 
srfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesiadllea
Chronophin_1 25-303 1.7e-56 182.6 In-house 2-256 (261) alignment 
Range on Protein: 25-303
Range on HMM: 2-256/261.0
ESVILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKAKGFGIE-IKEDNVLTSSFSCANFLAVKNFQKKVFVMGEKGVHFELEK
..|.|| ||||..  .|..|| .. . ..  |.......|||   |.|.|.. |..|.. ........| .. |..|  .. . ||.|.||.|.  ||..
qlvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelre

FGICSLKMSEKlekpmhefvteleldpDVGAVIVGRDEGFNMAKLVRTGSYLLNPdVIFLGTCLDAAYPIGNNrVMVGAGATLAAMKAYTGRSPLVLGKP
 |.   .  |.                .| ||.|| || .. .|| .   .. ..   |. |  |   |  .  .. |.|.  ||..| .|| ||| |||
aGlrlvdeped................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeG.iaPgtGslaaaveaAsgreplvvGKP

NPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVGSGVNTPKEVQQIIeegdpkkKILVPDTYLPSLGHML
.| |  . ... ...|| |.|||| |.||.......|...|.| .|| ...|.|..        | |.||... |.  .|
epvmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk.......kdlrPdavvesiadll
Hydrolase_6 Haloacid dehalogenase-like hydrolase 27-126 8.8e-29 90.9 Pfam-A 1-100 (101) alignment 
Range on Protein: 27-126
Range on HMM: 1-100/101.0
VILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKAKGFGIEIKEDNVLTSSFSCANFLAVKNFQKKVFVMGEKGVHFELEKFGI
...| |||||...|||.||..... .. .| ......|||  |..|.|.| . .|....|..|.||. ..|..|. ....|||.|.||.|.. ||.. |.
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkeaGf
subfamily_LHPP_pd Subfamily LHPP 27-273 4.5e-25 79.9 In-house 1-223 (227) alignment 
Range on Protein: 27-273
Range on HMM: 1-223/227.0
VILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKAKGFGIEIKEDNVLTSSFSCANFLAVKNFqKKVFVMgEKGVHFELEKFGi
|.||  |||.  ..|| |||.  . .  .| |. ...|... |....... . .|....|....||    .. |  ..  ...... |..|. ..|..  
vllDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerkl.rpyllv.eddveedfedid.

CSLKmseklekpmhefvteleldpdvGAVIVGR-DEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMVGAGATLAAMKAYTGRSPLVLGKPNP
.. .                       ||..|  .| |. ..| ..   ||. .   | .   . |   .. ...|.||  .|..  || .  |.|||..
tdkp......................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevvGKPsa

WMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVGSGVNTP
 . .. ...  ..||. .|.|| .. |.. | ..|.....| .|.  |
lffekaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkfrp
Hydrolase_like HAD-hyrolase-like 220-278 1e-14 45.5 Pfam-A 2-60 (75) alignment 
Range on Protein: 220-278
Range on HMM: 2-60/75.0
LGKPNPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVGSGVNTPKEVQQ
||||||.|    ..   ..|. ..|.||.| ||. .| |.| .|. | .|| .... ..
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlkl
subfamily_CUT_pd Subfamily CUT 26-130 5.6e-08 22.6 In-house 20-127 (391) alignment 
Range on Protein: 26-130
Range on HMM: 20-127/391.0
SVILDADGVLWHFSKAIDGAVDTFNYMNTT--GRKI--FIISNNSEISRQEMADK-AKGFGIEIKEDNVLTSsFSCANFLAVKnFQKKVFVMGEKGVHFE
...|| ||||    | | .| . .. ..      |.   .. |..... .| |.| ..  ..|.. |.|| |  |    || | ..|...|.|.. |.  
givlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvlls.hsPlkllaek.ydkrllvvgqesvrev

LEKFGICSLK
 | .|   ..
aeglGfknvv
Subfamily.CECR5.protein 26-130 6.6e-08 22.4 In-house 22-129 (393) alignment 
Range on Protein: 26-130
Range on HMM: 22-129/393.0
SVILDADGVLWHFSKAIDGAVDTFNYMNTT--GRKI--FIISNNSEISRQEMADK-AKGFGIEIKEDNVLTSsFSCANFLAVKnFQKKVFVMGEKGVHFE
...|| ||||    | | .| . .. ..      |.   .. |..... .| |.| ..  ..|.. |.|| |  |    || | ..|...|.|.. |.  
givlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvlls.hsPlkllaek.ydkrllvvgqesvrev

LEKFGICSLK
 | .|   ..
aeglGfknvv
CECR5_TIGR01456 26-126 1.3e-06 18.1 In-house 40-143 (370) alignment 
Range on Protein: 26-126
Range on HMM: 40-143/370.0
SVILDADGVLWHFSKAIDGAVDTFNYMNTT-GR-K--IFIISNNSEISRQEMADK-AKGFGIEIKEDNVLTSSfSCANFLaVKNFQKKVFVMGEKGVHFE
...|| ||||   .| | || . .  ..   |. |  .... |  ..| .. |.. ..  |.|.. . |. |  |    | |....|.. . |.  |   
gfaldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglseraraeelsalLgvevsplqviqsh.sPykkl.vnkyekrilasGkgevaev

LEKFGI
 | .| 
aegyGF
Hydrolase haloacid dehalogenase-like hydrolase 27-260 1.5e-06 20.1 Pfam-A 4-215 (215) alignment 
Range on Protein: 27-260
Range on HMM: 4-215/215.0
VILDADGVLWHFSKAI--DGAVDTFNYMNTT--------GRKIFIISNNSEISrqE---MADKAKGFGIEIKEDNVltssfscanflavknfqkkvfVMg
|. | .|.|.. ....   |.    ..  ..        | .. ... ..     .      .  | |...| |..                     |  
vvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstr..ggltgfatfigrgvsgkvdgi.....................vl.

ekGVHFELEKFGICSLKMSEKLEKPMHEFVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDV-IFLGT------CLDAAYP--IgnNRVMVGAGA
  | .  ... |.  .  ... .   ..  | ...  .. |. |  ..   . ..  .  .|    . ..| |         .|    |  ....| |..
..gnpewmtalglrviapdlvaaegqskgrtvvvvavqaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqagi..edslvfaev

TlaamkaytgrsplvlGKPNPWMASTLMQSGAIKPETTLMVGDTLqTDMHFASNCG
.               |||.| .   ...   |.|. ..||||.. .|. .. ..|
v...............gkPepklfvaaieeLqidpgevamvGDgv.nDapalaaAg
Acid_phosphat_B HAD superfamily, subfamily IIIB (Acid phosphatase) 39-86 7.1e-06 13.8 Pfam-A 115-162 (230) alignment 
Range on Protein: 39-86
Range on HMM: 115-162/230.0
SKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKAKGFGIEIKE
.|||.||.. .....  | ||| .|. || ....  .. |  |.. .|
akaipgalelikkvverGvkiffvsgRseeqkaaTvenLkkagfsswe