Gene CG5567 in Drosophila melanogaster

Synonym: Dmel\CG5567, Phos5567, Dmel_CG5567, CG5567

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP078_AA protein Get Run
DmelP078_AA_39-322 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 42-320 2.3e-116 379.0 In-house 2-277 (279) alignment 
Range on Protein: 42-320
Range on HMM: 2-277/279.0
VITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVELGFH-IKENGIISTAHATAAYLKRRNFSKRVFVIGSEGITKELDAVG
|..|||||||.  .|..|.....|.|| .||...|.||||||.|.|||||  .|||. .||. |.|.|.|.|.|||...|.|.|.|.|.||...||...|
vlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlgeeglkeeLkeag

IQHTEVGPEPMKGSLAEFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLNDPECLFVATNTDERFPMPN-MIVPGSGSFVRAIQTCAERDPVVIGKP
|.... ||| .|..|.| ....||||.|.||||||.||..|..|..|||.||..||.||.|||.|. .|... ...||.||.|.||.....|.|.|.|||
iellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkkevvipgaGslvaaieaasgrkplvlGKP

NPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNCGFQTLLVGSGIHQLKDVERWKLSQdpeekKLIPDVYLPKLGDLLP
|. ..|.|.....|||.|||||||| .||||.| |||.|||||.||...|.|||..| ..     ||.||.||..|.|||.
nelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee.....klvPdyyldsladlle
Chronophin_2 41-322 7.3e-74 239.5 In-house 2-280 (282) alignment 
Range on Protein: 41-322
Range on HMM: 2-280/282.0
SVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVELGF-HIKENGIISTAHATAAYLKR-RNFSKRVFVIGSEGITKELDA
.|. |||||.|   .|. |...|...|. .|| . | |||||..| .. .|   |||  .... |.|.|. .||||.   . . .|||||.||. ||| .
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadvrgkvfviggeglrkelre

VGIQHTEVGPEPMkgslaeFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLNDPECLFVATNTDERFPMPN-MIVPGSGSFVRAIQTCAERDPVVIG
 |..  |   |.           .  || |. ||.||.||...| |. ||..|| |..||..||..|   |. .  |.|||||.  |..| . |  .|||
agvpvvedadeqe......asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvig

KPNPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNCGFQTLLVGSGIHQLKDVERWKLSQDPEEKKLIPDVYLPKLGDLLPSI
|| . . | .  . ..||.|.|||||| .||||.| |||..|.|  .|. .|.. .... || .|...|.|| ..  . |||...
kpsrfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesiadlleal
Chronophin_1 40-320 4.9e-73 236.8 In-house 2-257 (261) alignment 
Range on Protein: 40-320
Range on HMM: 2-257/261.0
DSVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVELGFH-IKENGIISTAHATAAYLKRRNFSKRVFVIGSEGITKELDA
..|..|.||||.  ..|..|  .....||  ||.. | ||||..||.|| ..  .||.. .... |.|.| |.||.|.. . . .|.|.|.||..|||..
qlvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelre

VGIQHTEvGPEPmkgslaefmaqhlkldtDIGAVVVGFDEHFSFPKMMKAASYLNDPeCLFVATNTDERFPMPNMIVPGSGSFVRAIQTCAERDPVVIGK
 |.. .. .||.                 .. |||||.||..|| |. .|. ...|. .|||||| |  .|... |.||.|| ..|... ..|.|.|.||
aGlrlvd.eped.................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeGiaPgtGslaaaveaAsgreplvvGK

PNPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNCGFQTLLVGSGIHQLKDVERWKlsqdpeeKKLIPDVYLPKLGDLLP
|.|.. |. . . ..||..|.|.||| .|||| | ..|..|||| .|. .|..... |       |.| || .. .. ||| 
PepvmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk.......kdlrPdavvesiadlle
subfamily_LHPP_pd Subfamily LHPP 42-290 2.3e-34 110.3 In-house 1-224 (227) alignment 
Range on Protein: 42-290
Range on HMM: 1-224/227.0
VITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVELGFHIKENGIISTAHATAAYLKRRNFskRVFVIGSEGITKELDAVGI
|. |  |||.. ..|. |.|.....|.  |. . |.||.. ... .|...  .|||...|. |.....|....|..|.   | ... ...  ......  
vllDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerkl..rpyllveddveedfedidt

QHTevgpepmkgslaefmaqhlkldtdiGAVVVGF-DEHFSFPKMMKAASYLND-PECLFVATNTDERFPMPNMIVPGSGSFVRAIQTCAERDPVVIGKP
..                           |||.|  .|.|.. .. .|   | . ..   .| |..  .  ..  . | |.||.|..  .. .  |.|||
dkp.........................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevvGKP

NPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNCGFQTLLVGSGIHQLK
.... |. ..| ..||.. .||||  . |.    ..|....|| .| .. .
salffekaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkfrpe
Hydrolase_6 Haloacid dehalogenase-like hydrolase 42-142 2.1e-32 102.5 Pfam-A 1-101 (101) alignment 
Range on Protein: 42-142
Range on HMM: 1-101/101.0
VITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVELGFHIKENGIISTAHATAAYLKRRNFSKRVFVIGSEGITKELDAVGI
...|.|||||   .|..|.......|. .|| ....||||.|...|..||  .||....|. ....| |.|.|||.|.. |.|.|||.||. .||...|.
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkeaGf

Q
.
k
Hydrolase_like HAD-hyrolase-like 236-295 1.6e-15 48.2 Pfam-A 2-61 (75) alignment 
Range on Protein: 236-295
Range on HMM: 2-61/75.0
IGKPNPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNCGFQTLLVGSGIHQLKDVERW
.||||| . ..   . ...||...||||. .|||. . |.| ...|| .|... .| .. 
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlkla
Hydrolase haloacid dehalogenase-like hydrolase 41-270 8.4e-10 30.7 Pfam-A 3-209 (215) alignment 
Range on Protein: 41-270
Range on HMM: 3-209/215.0
SVITDCDGVLWIYGQAL--EGSVDVMNQLKGM---------GKSIYFCTNNSTK-TrSELLKKGVELGFHIKENGIISTAHATAAYLKRRNFSKRVFVIG
 |. |..|.|.   ...  .|   . . .. .          . ......|||. .  .   .    |  .| .||. . . ... |  | ......   
tvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstrgg.ltgfatfigrgvsgkvdgivlgnpewmtalglrviapdlvaae

SEGITKELDAVGIqhtevgpepmkgslaefmaqhlkldtdigAVVVGFDEHFS---FPKMMKAASYLNDPEC-LFVAT-------NTDERFPMPnmivpg
 . . ..  .|..                             ....  . .|.    |....|  .|..  . ....|       ... ...        
gqskgrtvvvvav.............................qaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqagi......

SGSFVRAIQTcaerdpvviGKPNPAICESLVTEKKIDPSRTLMIGDRAnTDIL
 .|.| |  .         |||.| . . .. | .|||....|.||.  .|. 
edslvfaevv.........gkPepklfvaaieeLqidpgevamvGDgv.nDap