subfamily_CDKN3_pd |
Subfamily CDKN3 |
2-203 |
1.4e-126 |
413.8 |
In-house |
1-202 (202) |
alignment |
Range on Protein: 2-203
Range on HMM: 1-202/202.0
KPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGI
|||||||||||||||||.||.|..||.|.||.|||||....|||.|||||||.||||.|.||.|||||.|..|.||.|||||||||||..|||||||.|.
kppssiqtsefdssdeeqievekspiqidwldlsrvniaeklglsalpgckfddvrrsvekdieelksqgvedvfvlctrgelskyrvrrlldlyqqagl
ITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKLAAHLS
|.||.|||||..||||||..|.|||...||.|||||.|||||||||.||.|||||||.|||.|..|||.||||.||.||||.||||||.||||||...||
ivhhypiadglvpdiasclkileelrinlkayrktlvhcygglgrsslviaclllylddtiepkdaidklrdlkgsraiqtvkqynylsefrdkleeyls
SR
||
sr
|
CDKN3 |
Cyclin-dependent kinase inhibitor 3 (CDKN3) |
1-168 |
2.7e-120 |
389.5 |
Pfam-A |
1-168 (168) |
alignment |
Range on Protein: 1-168
Range on HMM: 1-168/168.0
MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCG
||||.|||.||||||||||.|.|||||.|||||||||||||||||||||||||||||||||||||||||.||||.|||||||||||||||||||||||.|
mkppisiqasefdssdeepveeeqtpiqiswlslsrvncsqflglcalpgckfkdvrrnvqkdteelksygiqdvfvfctrgelskyrvpnlldlyqqyg
IITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAI
|.|||||||||||||||||.||||||.|||||||||||||||||||||||||||||||||.|||||||
ivthhhpiadggtpdiascleimeelatclknyrktlihcygglgrsclvaaclllylsdsispeqai
|
CDKN3 |
Cyclin-dependent kinase inhibitor 3 (CDKN3) |
1-168 |
2.7e-120 |
389.5 |
In-house |
1-168 (168) |
alignment |
Range on Protein: 1-168
Range on HMM: 1-168/168.0
MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCG
||||.|||.||||||||||.|.|||||.|||||||||||||||||||||||||||||||||||||||||.||||.|||||||||||||||||||||||.|
mkppisiqasefdssdeepveeeqtpiqiswlslsrvncsqflglcalpgckfkdvrrnvqkdteelksygiqdvfvfctrgelskyrvpnlldlyqqyg
IITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAI
|.|||||||||||||||||.||||||.|||||||||||||||||||||||||||||||||.|||||||
ivthhhpiadggtpdiascleimeelatclknyrktlihcygglgrsclvaaclllylsdsispeqai
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
27-196 |
3.7e-45 |
149.1 |
In-house |
3-172 (176) |
alignment |
Range on Protein: 27-196
Range on HMM: 3-172/176.0
IHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEEL
.....| |. . . . | |...|.... ...|..... |.||. ||. .. .... ||.....||. ..... || .|.|. |.|.||.. ..|..|..
lrllgldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefi
TTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKL
..||. ...|.||..|.||.....|..||.|. .|.|.|.. .|. | ||.|| .|| .|.|| .|
realkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll
|
PTEN_1 |
|
37-197 |
5.7e-31 |
102.8 |
In-house |
32-193 (196) |
alignment |
Range on Protein: 37-197
Range on HMM: 32-193/196.0
VNCSQFLGLC-ALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELskYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLK---N
. . ..|. ... .... .. |..| ..||. || .. .. . || .... |..... |.. .| || | |.|.... ..| ... .|. |
mgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeel..sgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpn
YRKTLIHCYGGLGRSCLVAACLLLYLSDtISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKLA
.. |.|| .||||| .|.|..|.|. ....|.. .|. | ||... .| .|..|.. ||
gnvVlVHCkaGlgRsGtvvaayLmykgk.ltadeAlelvrekRppgapnspsqerlleyfaella
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
27-196 |
4.5e-29 |
96.8 |
In-house |
5-169 (174) |
alignment |
Range on Protein: 27-196
Range on HMM: 5-169/174.0
IHISWLSLSRVNCSQFLGLCALPgckfkdvrrnvqkDTEELKSCGIQDIFVFCTRGELSKYRVPNLL----DLYQQCGIITHHHPIADGGTPDIASCCEI
|. |.|.||... ..| . |. . |.||. ||.... ... || .|...|. . . . || .. |. |.|.||.. .|.
inaspldlsyitprliagqgpla.............fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillef
MEELTTCLKN--YRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLR--GSGAIQTIKQYNYLHEFRDKL
.... ..|.. ...|.|| .|.||. ...|..|.. |...|.| .| || .|..|| || .|..|...|
vkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
23-198 |
8.2e-28 |
92.7 |
In-house |
4-162 (172) |
alignment |
Range on Protein: 23-198
Range on HMM: 4-162/172.0
EQTPIHISWLSLSRVNCSQFLGLCAlpgckfkdVRRNVQKDTEELKSCGIQDIFVFCTRgelskyrvPNLLDLYQQCGIITHHHPIADGGTPDIASCCEI
. |. |.|.|... .. . .. |... .. . ||. ||. |. ... .. .|... || ...|. |.|.|... |.
gsdyinasyldlyyipdrfiatqgp........lrntladfwrmlkelgithivnltel........lydpellerlgiqylylpwpDhgvpllelllef
MEELTT--CLKNYRKTLIHCYGGLGRSCLVAACLLLYlsDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFRDKLAA
.| . . .|.. ..|.||..|.||.....|..|.. .|.|.|.. .|. | .||.|. ||..|..| ..|
lefidellalspggpvlVHCsaGvgRtgtlvaaylml..lglsleeavalvrekR.pgavqnpsqyrflyyfekllll
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
23-192 |
1.1e-27 |
92.4 |
In-house |
36-238 (245) |
alignment |
Range on Protein: 23-192
Range on HMM: 36-238/245.0
EQTPIHISWLSLSRVNCSQFLGLCALPGckfkdvrrNVQKDTEELKSCGIQDIFVFCTRGELSK-----------------------------------Y
..|. |. ...|.. ... . ||. .|.. . |.. ||. |. ... ||.. .
dsdyinasyvdgyritpkfiatqgPlpe........tvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtl
RVPNLLDLYQQCGIITHHHPIADGGTPD-IASCCEIMEELTTCLK--NYRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRgSGAI
.| || | ... .| |..|. |.|.|| ... ....|.. ..|. . ..|.|| .|.||.....|..|.. ..|.|.|.. ||. | .||.
evtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR.pgav
QTIKQYNYLHEF
|| || .|.|.
qtpsqyrflyea
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
35-192 |
2.3e-27 |
91.6 |
In-house |
38-237 (243) |
alignment |
Range on Protein: 35-192
Range on HMM: 38-237/243.0
SRVNCSQFLGLCALPGCKfkdvrrNVQK----DTEELKSCGIQDIFVFCTRGELSKYRVPNL----------------------------------LDLY
. ... | .. .| . .|. . . |.. ||. | ... ||... .. . || .
nliyvtprliatqgPlpe......tveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddl
QQCGIITHHHPIADGGTPD-IASCCEIMEELTT---------CLKNYRKTLIHCYGGLGRSCLVAACLLLYLS-DtISPEQAIDSLRDLRGSGAIQTIKQ
.. .| |..|. |.|.|| .... ....|... .|.. ...|.||..|.||. ...|..|..| . ...|.|.. ||. |. |.|| |
trlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllg.vdleeavkllreqRpgkavqtpsq
YNYLHEF
| .|.|.
yrflyea
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
32-196 |
7e-25 |
83.1 |
In-house |
21-170 (178) |
alignment |
Range on Protein: 32-196
Range on HMM: 21-170/178.0
LSLSRVNcsQFLGLCALPGckfkdvrrnvQKDTEELKSCGIQDIFVFCTRGElsKYRVPNLLDLYQQCGIITHHHPIADGGTPD-IASCCEIMEELTTCL
. .|.. .| |..|| ..| | || ||. | ... | ...... ... || .| || |.|.|| .. . |..| . ..|
inaseil..pglylgslpp..........addlellkelgithivnlteele..lgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeal
-KNYRKTLIHCYGGLGRSCLVAACLLLYLSdTISPEQAIDSLRDLRGsgAIQTIKQYNYLHEFRDKL
.. ...|.||. |.|||....|. |.. .|.|.||. .| | .... |...|.|| .|
dekggpvlVHCsaGvgRsgtlvaaylmkkl.glsleeaielvrerRp..ivpnpgqlrqLyefelrl
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
59-195 |
9e-25 |
82.6 |
In-house |
21-148 (152) |
alignment |
Range on Protein: 59-195
Range on HMM: 21-148/152.0
NVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLdlyqqcgiITHHHPIADGGTPDIASCCEIMEELTTC--LKNYRKTLIHCYGGLGRSCLVAACLLL
.. .. . ||. ||. | . ... || |. .... .|.|. |.|.||.. . ... .. . |.. ..|.||..|.||. ...|..|.
tladfwrmlkelgittivmltellelgklkceqyi........qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylm
YlsDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFRDK
. .|.|.|.. .| | .||... |. .|.|| ..
l..lgvsleeavalvrekR.pgavpnpgqlrflyefekl
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
37-196 |
3.1e-24 |
81.3 |
In-house |
23-271 (278) |
alignment |
Range on Protein: 37-196
Range on HMM: 23-271/278.0
VNCSQFLGLCALPGCKFKDVRRN-------------------------------VQKDTEELKSCGIQDIFVFCTRGELS--------------------
.. .| |. |. ...||. . |... . |.. ||. | .. ||.
seitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdft
---------------KYRVPNL---LDLYQQCGIITHHH-PIADGGTPDIA---SCCEIMEELTTCLK--------------NYRKTLIHCYGGLGRSCL
...| || ... |. .| |. |.|.|. | |..|.. .|| . ..|.||. |.||..
vtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGt
VAACLLLYLS--DTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKL
..|. |.. .......|.. || |. |.|. ||..|.|| .|
lvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
60-195 |
3.2e-24 |
80.7 |
In-house |
18-143 (144) |
alignment |
Range on Protein: 60-195
Range on HMM: 18-143/144.0
VQKDTEELKSCGIQDIFVFCTRGELSKYRVPnlldlyqqcGIITHHHPIADGGTPDI-ASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYL
. .| |.||. || .. ... | . .. || .| |. | |.||. . ..|..| . ..|.. ...|.||..|.||.....|. |...
taldlellkklgittvinlteeyepeflere.........giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkk
SDtISPEQAIDSLRDLRGsGAIQTIKQYNYLHEFRDK
. .|.|.|.. .| | ||... |...|.|....
lg.lsleealalvrsrrp.gavpnpgqlrfLleyekl
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
60-195 |
2.3e-23 |
77.9 |
In-house |
18-141 (145) |
alignment |
Range on Protein: 60-195
Range on HMM: 18-141/145.0
VQKDTEELKSCGIQDIFVFctrgelskyrvPNLLDLYQQCGIITHHHPIADGGTPDI-ASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYL
. .| |.||. || .. . . |.|. . || .. |. | |.||. . .|..| . ..||. ...|.||. |.||.....|. |..|
taldlellkdlgittvlnl...........tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll
SDtISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFRDK
. .|.|.|.. .| | .||... |...|.|| .
lg.vsleealelvrsqr.pgavpnpgqlrflyefele
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
65-193 |
1.8e-22 |
75.6 |
In-house |
119-285 (297) |
alignment |
Range on Protein: 65-193
Range on HMM: 119-285/297.0
EELKSCGIQDIFVFCTRGELSKYRVP--------------NLLDLYQQCGII-----------------THHHPIADGGTP-DIASCCEIMEELTTCLK-
. .. |.. | .. ||... .. .||. .. |.. ..... |.|.| ......|..|.. ..|.
rmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealae
--NYRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFR
. ...|.|| .|.||.. ..|..|.. ......|.. || | .||.|| || .|...
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqR.pgavqtpsqyrflydal
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
58-192 |
1.9e-22 |
75.1 |
In-house |
45-166 (182) |
alignment |
Range on Protein: 58-192
Range on HMM: 45-166/182.0
RNVQKDTEELKSCGIQDIFVFCtrgelskyRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTclkNYRKTLIHCYGGLGRSCLVAACLLLY
..| .. . ||. ||. | . .. .|... || ...|. |.|.||. ......|| . ...|.|| .|.||.. ..|. |..
stvadflrmlkelgittivnlt........eelywpellerlgiqylylpwpDhgvpdldelldfieevle...eggpvlVHCsaGvgRtgtlvaaylmk
LSDtISPEQAIDSLRDLRgSGAIQTIKQYNYLHEF
. .|.|.|.. .| | .|...| || .|. .
klg.vsleeavklvrsrR.pgmvitpnqyfflqla
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
24-193 |
7.1e-22 |
74.0 |
In-house |
90-276 (314) |
alignment |
Range on Protein: 24-193
Range on HMM: 90-276/314.0
QTPIHISWLSL----------------SRVNCSQFLG---------------------LCALPGCKfkdvRRNVQKDTEELKscgiqdifvfctrgelsk
|.| | . .. . |. . |. |.| . .| |.||
qgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng....neptaadlellk..................
yRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTClKNYRKTLIHCYGGLGRSC--LVAACLLLYLsDTiSPEQAIDSLRDLRG----SGAI
.. . .|... || ...|. ||..|... |..| . .. .. ...|.|| .| ||.. .|||.|...| . |.|.|.. .| | |.|
.eelydpelferlgikylripvpDgsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkll.gv.sleealedvrlkRpinpnpgfi
QTIKQYNYLHEFR
.. .|| . .|..
eqleqyefileal
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
66-192 |
1.6e-21 |
72.5 |
In-house |
107-272 (278) |
alignment |
Range on Protein: 66-192
Range on HMM: 107-272/278.0
ELKSCGIQDIFVFCTRGELSK----------------------------------YRVPNLLDLYQQCGIITHHHPIADGGTP-DIASCCEIMEELTTCL
.. |.. | . .. ||.. .| || | . . . . |.... |.|.| .... ....... ..|
mvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreal
K-NYRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEF
. . ..|.|| .|.||.....|..||. ....|.|.. || | ||.|| || .|.|.
edsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqR.pgavqtpsqyrflyea
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
65-192 |
1.5e-20 |
69.6 |
In-house |
125-299 (307) |
alignment |
Range on Protein: 65-192
Range on HMM: 125-299/307.0
EELKSCGIQDIFVFCTRGEL---------------------------------SKYRVPNLLDL-YQQCGIITHHHPI---ADGGTP-DIASCCEIMEEL
. |. |.. | .. || ..|. .. || . . ... .|.. |.|.| .........||.
rmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev
TTCLK---NYRKTLIHCYGGLGRSCLVAACLLLYLSDT-------ISPEQAIDSLRDLRgSGAIQTIKQYNYLHEF
..|. . ..|.|| .|.||.. ..|..|.. .....|.. ||. | .||.|. || .|.|.
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR.pgavqnpeqyrflyea
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
61-202 |
6.6e-20 |
67.3 |
In-house |
35-230 (272) |
alignment |
Range on Protein: 61-202
Range on HMM: 35-230/272.0
QKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLdlyqqCGIITHHHPIADGGTPDIA-------------------------------------------
..| . ||. || |. ... |. .. .. .. || .|.|| | ..|.|
aadfwrlkelgiktivdLrseeErgrlkcdryw.....pgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytd
---------SCCEIMEELTTclknYRKTLIHCYGGLGRSCLVAACLLLYlsDTIS--------------PEQAIDSLRDLRgSGAIQTIKQYNYLHEFRD
...|..|.| . .. |.||..| .|. .|.|.|||. .| .|.|.. ||. | ||.|| || .|.|.
wpdhgvpqeallellellld....ggpvlvHCsaGkdRTGtvvalllll..lgvsletivddYlltnlyleeaveelraqr.pgavqteeqylflyeall
KLAAHLSS
.|. | |
ellrslls
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
60-191 |
6.9e-20 |
66.6 |
In-house |
22-147 (151) |
alignment |
Range on Protein: 60-191
Range on HMM: 22-147/151.0
VQKDTEELKSCGIQDIFVFCTRGELSkyrvpNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKN--YRKTLIHCYGGLGRSCLVAACLLLY
. . |.||. ||. |. ... | .. ..... || .| || | .|.. . ... |. | . ..|.|| .|.||. ...|..|..
ladflellkelgiktivnlrseeerg.....ycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml
LSdtISPEQAIDSLRDLRGsGAIQTIKQYNYLHE
| .|.|.|.. .| |. |..|. |. ...
lg..vsleealeeyrlkrp.gvvqpnqqflfqlf
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
69-192 |
4.9e-19 |
64.2 |
In-house |
108-271 (317) |
alignment |
Range on Protein: 69-192
Range on HMM: 108-271/317.0
SCGIQDIFVFCTRGELSKYRVP----------------NLLDLYQQCGIITHHHPI-------------------ADGGTP-DIASCCEIMEELTTCLKN
|.. | ... ||.. .||. .. ||. .. .. |.|.| .. .. ...|.. ..|..
eqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealed
-YRKTLIHCYGGLGRSCLVAACLLL-----YLSdTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEF
..|.|| .|.||.. ..|..|. . ....|.|.. || | .||.|| || .|...
pggpvlVHCsaGvgRtGtfiaaylmleqlekeg.gvdveeavkelreqR.pgavqtpeqyrflyda
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
59-192 |
7.6e-19 |
63.8 |
In-house |
66-241 (249) |
alignment |
Range on Protein: 59-192
Range on HMM: 66-241/249.0
NVQKDTEELKSCGIQDIFVFCTRGELSKYRVP-----------------------------------NLLDLYQQCGIITHHHPIADGGTP-DIASCCEI
| .. . |. ||. | ... || . || | ..... | |.| ........
tvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldf
MEELTTCLK---NYRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEF
.|.. ..|. . ..|.|| .|.||.....|..|.. ....|.|.. ||. | .||.|. || .|.|.
ieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqR.pgavqnpeqyrflyea
|
0038934 |
(Phosphotyrosine protein) phosphatases II |
64-196 |
4.8e-17 |
57.7 |
In-house |
35-176 (194) |
alignment |
Range on Protein: 64-196
Range on HMM: 35-176/194.0
TEELKSCGIQDIFVFCTRGELSKYRVPNLL--------DLYQQCGIITHHHPIAD-GGTPDIASCCEIMEELTTCLKNY--RKTLIHCYGGLGRSCLVAA
.|||. .. |.. ... . | .| ..... || .. |. | | .|... ..... . . |.. . ..||..||||. ...|
ieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva
CLLLYLSDTiSPEQAIDSLRDLRgSGAIQTIKQYNYLHEFRDKL
. |.| . |.|.||. .|. | |||........|... . |
aYLiyrlgm.saeeAialfrekR.pgaipnqdyleallkrykel
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
101-191 |
5.7e-17 |
57.5 |
In-house |
169-266 (273) |
alignment |
Range on Protein: 101-191
Range on HMM: 169-266/273.0
IITHHHPIADGGTP-DIASCCEIMEELTTCLK---NYRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHE
.. |.... | |.| ...|. |..|.. ..|. . ....|| .|.||.. ..|..||. ......|. ||. | |..|| || .|.|
thfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqR.pgmvqtpeqyrflye
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
101-193 |
2e-16 |
55.6 |
In-house |
171-273 (297) |
alignment |
Range on Protein: 101-193
Range on HMM: 171-273/297.0
IITHHHPIADGGTPD-IASCCEIMEELTTCLK---NYRKTLIHCYGGLGRSCLVAACLLL----Y---LSDTISPEQAIDSLRDLRGSgAIQTIKQYNYL
. |.. . | |.|. .||. ...|.. ..|| . ..|.|| .|.|||. ..|. |. .... .|. .||. | |.|| || .|
thfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpg.avqtleqyrfl
HEFR
.|.
yeal
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
101-192 |
1.2e-15 |
53.2 |
In-house |
168-269 (284) |
alignment |
Range on Protein: 101-192
Range on HMM: 168-269/284.0
IITHHHPIADGGTP-DIASCCEIMEELTTCLKN---YRKTLIHCYGGLGRSCLVAACLLLYLS----D---TISPEQAIDSLRDLRgSGAIQTIKQYNYL
.. |.... | |.| .... |..... ..|.| ....|| .|.||.. ..|. ||. . ......|. ||. | |..|| || ..
thfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqR.pgmvqtleqyrfv
HEF
.|.
yea
|
subfamily_PTPDC1_pd |
Subfamily PTPDC1 |
93-197 |
2e-15 |
51.7 |
In-house |
75-176 (182) |
alignment |
Range on Protein: 93-197
Range on HMM: 75-176/182.0
LDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYrKTLIHCYGGLGRSCLVAACLLLYlSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEF
|. ... ||. . ...| |.. . . .|. .. .|.. |. .||. |||| .. || |.| .. ...|.||. .|. | . .||| .| . ..||
lealmeqgiyvynfgwkDygvasleriLdivkvvafalqeg.kvavhChaGlGrtGvliacylvy.akrltaekaiklvrskr.pksiqtreqvelvkef
RDKLA
. |.
alfli
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
102-192 |
1.4e-14 |
49.6 |
In-house |
199-294 (308) |
alignment |
Range on Protein: 102-192
Range on HMM: 199-294/308.0
I--THHHPIADGGTPD-IASCCEIMEELTTCLKNyRKTLIHCYGGLGRSCLVAACLLL----YLSDTISPEQAIDSLRDLRGSgAIQTIKQYNYLHEF
. |.. |.|.|. .... ...|.. ..|.. ....|| |.||.. ..|..|| ......|. || | ..|| || .|..
vthfhytnWpdhgvPpspeilldflelvrkslpg.gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpg.mvqtpeqylflyra
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
100-191 |
1.4e-13 |
46.4 |
In-house |
184-280 (288) |
alignment |
Range on Protein: 100-191
Range on HMM: 184-280/288.0
GIITHHHPIADGGTPD-IASCCEIMEELTTCLKN-YRKTLIHCYGGLGRSCLVAACLLL----YLSDTISPEQAIDSLRDLRGSgAIQTIKQYNYLHE
.. |.. . | |.|| . .. ...... ..|.. ...|| |.||.. ..|..|| ......|. || | ..|| || ...|
vthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpg.mvqtpeqyrfvye
|
subfamily_PTPMT1_pd |
Subfamily PTPMT1 |
88-197 |
1.7e-10 |
35.6 |
In-house |
61-169 (171) |
alignment |
Range on Protein: 88-197
Range on HMM: 61-169/171.0
RVPNLLDLYQQCGIITHHHPIADGG-TPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYlSDTISPEQAIDSLRDLRGSGAIQTiKQY
.. | . ... |. . .. | .||... . .| .. .. .. .|| .| ||| ..|| |.. .. .|||.|.. |.. | ... ||.
alansteewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmk.keklspeeAlkalkkkRkiirlak.kqw
NYLHEFRDKLA
. |.|...||
kalqeyeekll
|
subfamily_PRL_pd |
Subfamily PRL |
61-195 |
1.6e-09 |
32.0 |
In-house |
24-148 (151) |
alignment |
Range on Protein: 61-195
Range on HMM: 24-148/151.0
QKDTEELKSCGIQDIFVFCTrgelSKYRVPNLldlyQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKT--LIHCYGGLGRSCLVAACLLlyL
.| .|||| ... . | .| . .| .. || . . .||..| . | .| | . |. |. .|| ||||. .. | | .
ekfieelkkeevktvvrvce....ptydtekl....ekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalal..i
SDTISPEQAIDSLRDLRgSGAIQtIKQYNYLHEFRDK
. ...|.|.. .|. | ||| || ..|.... |
eaGmkyedavefirekr.rgain.skqlkflekykak
|
PTPc_DSPc_SM00012 |
|
104-191 |
2.8e-09 |
32.5 |
In-house |
6-101 (105) |
alignment |
Range on Protein: 104-191
Range on HMM: 6-101/105.0
HHHPIADGGTPD-IASCCEIMEELTTCLKNY---RKTLIHCYGGLGRSCLVAACLLLYLS-----DTISPEQAIDSLRDLRgSGAIQTIKQYNYLHE
|.. . | |.|. | .|..... .. .. ...|| | ||.. ..| .|. . .... .| . .||. | .|..|| || .|..
hytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqR.pgmvqteeqylflyr
|
Y_phosphatase |
Protein-tyrosine phosphatase |
101-191 |
2.7e-08 |
28.9 |
Pfam-A |
136-231 (235) |
alignment |
Range on Protein: 101-191
Range on HMM: 136-231/235.0
IITHHHPIADGGTP-DIASCCEIMEELTTCL-KNYRKTLIHCYGGLGRSCL-VAACLLLYLSD---TISPEQAIDSLRDLRgSGAIQTIKQYNYLHE
|.. | |.| . | ...... . .. ....|| | ||.. ||. .|| . ... |.. .|| | |..|...|| .|..
kqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqR.pgmvqsleqYiflyk
|
Y_phosphatase |
Protein-tyrosine phosphatase |
101-191 |
2.7e-08 |
28.9 |
In-house |
136-231 (235) |
alignment |
Range on Protein: 101-191
Range on HMM: 136-231/235.0
IITHHHPIADGGTP-DIASCCEIMEELTTCL-KNYRKTLIHCYGGLGRSCL-VAACLLLYLSD---TISPEQAIDSLRDLRgSGAIQTIKQYNYLHE
|.. | |.| . | ...... . .. ....|| | ||.. ||. .|| . ... |.. .|| | |..|...|| .|..
kqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqR.pgmvqsleqYiflyk
|
subfamily_PTEN_pd |
Subfamily PTEN |
72-177 |
1.3e-07 |
26.8 |
In-house |
47-158 (184) |
alignment |
Range on Protein: 72-177
Range on HMM: 47-158/184.0
IQDIFVFCTRGELSKYRVPNL--LDLYQQCG--IITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKT--LIHCYGGLGRSCLVAACLLLYLSDTISPE
..|.. | .. .|.. || |.. .. |. | .| . ||.|.... |.. .| .|| | ||. .. ...||. . ..|
ledvvkflekkhkdhykiynlrserkydskkfdgrvavypfdDhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekae
QAIDSLRDLRGS
.|.. | .
ealelfaeaRtk
|
DSPc |
Dual specificity phosphatase, catalytic domain |
122-193 |
2.6e-07 |
25.6 |
Pfam-A |
62-131 (133) |
alignment |
Range on Protein: 122-193
Range on HMM: 62-131/133.0
IMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYlSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFR
..| . .. .. .| |.||. |. || .... |.. .. .| ..|.. ... | | ..... | |..
avefiekaeqkgkkvlVHCqaGisRSatliiaYlmk.tknlslneAyefvkerr.skispnagflrqLleye
|
DSPc |
Dual specificity phosphatase, catalytic domain |
122-193 |
2.6e-07 |
25.6 |
In-house |
62-131 (133) |
alignment |
Range on Protein: 122-193
Range on HMM: 62-131/133.0
IMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYlSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFR
..| . .. .. .| |.||. |. || .... |.. .. .| ..|.. ... | | ..... | |..
avefiekaeqkgkkvlVHCqaGisRSatliiaYlmk.tknlslneAyefvkerr.skispnagflrqLleye
|
PTPc_motif_SM00404 |
|
117-194 |
2.9e-07 |
25.5 |
In-house |
64-139 (140) |
alignment |
Range on Protein: 117-194
Range on HMM: 64-139/140.0
ASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYlSDTISPEQAIDSLRDLRgSGAIQTIKQYNYLHEFRD
. .... . .. |. .| |.||. |. || .... |.. .. .| ..|.. ... | . .... . |.|...
kyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmr.yrqlslaeayefvkerR.piispnlnfvrqLieyek
|
subfamily_DSP23_pd |
Subfamily DSP23 |
69-192 |
8.9e-07 |
23.7 |
In-house |
29-141 (148) |
alignment |
Range on Protein: 69-192
Range on HMM: 29-141/148.0
SCGIQDIFVFCTRGELSKYRVPNLLdlYQQCGIITHHHPIADggtpDIASCCEIMEELTTclKNyRKTLIHCYGGLGRSCLVAACLLLYLsDTISPEQAI
|.. . . ..|. .||| ... .| .| | . .. ...|| || .|| | ||. . || |. .. .||
dlgvrylvslteegrphveatpnlt..lvrlriddyhppale....qvvefvrvveeaee..kn.eavsvhcllgrgrtgtmlacylvke.rklaaaeai
DSLRDLRgSGAIQTIKQYNYLHEF
.| || |...|..| . ....
aevrrlr.pgsvetveqeklvrdy
|
0048567 |
(Phosphotyrosine protein) phosphatases II |
102-177 |
2.1e-06 |
22.2 |
In-house |
39-120 (157) |
alignment |
Range on Protein: 102-177
Range on HMM: 39-120/157.0
ITHHHPIADGGTPDIASCCEIMEELTTCLK----NYRKTLIHCYGGL---GRSCLVAACLLLYLSDtISPEQAIDSLRDLRGS
. ......| | ...| . . . | || . .. .||. || ||. ....| |.. . ..||.||. || | .
lvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlg.ftpeeaiaplrivrpg
|
DSPc_SM00195 |
|
109-192 |
2.9e-06 |
22.2 |
In-house |
169-257 (263) |
alignment |
Range on Protein: 109-192
Range on HMM: 169-257/263.0
ADGGTP-DIASCCEIMEELTTCLKN-YRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRGSgAIQTIKQYNYLHEF
| |.| . |. |........ .. ...|| |.||.. ... ... .... .. . .||. | . ..|| .|| ...|
pdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpg.mvqtleqYlfiyea
|
PTPc_SM00194 |
|
109-192 |
2.9e-06 |
22.2 |
In-house |
169-257 (263) |
alignment |
Range on Protein: 109-192
Range on HMM: 169-257/263.0
ADGGTP-DIASCCEIMEELTTCLKN-YRKTLIHCYGGLGRSCLVAACLLLY----LSDTISPEQAIDSLRDLRGSgAIQTIKQYNYLHEF
| |.| . |. |........ .. ...|| |.||.. ... ... .... .. . .||. | . ..|| .|| ...|
pdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpg.mvqtleqYlfiyea
|