Gene DUSP21 in Homo sapiens

Synonym: LMWDSP21, DUSP21

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP14
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP018_AA protein Get Run
HsapP018_AA_19-164 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP14_pd Subfamily DSP14 17-172 3.7e-72 235.4 In-house 2-156 (157) alignment
Range on Protein: 17-172
Range on HMM: 2-156/157.0
PSIYSFSQITRSLFLSnGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASL
|.....||||.||||| ||||..| ||....||.|.|..||..|  ...|...||||.|.....|...||..|| |.......|.||.||.|||||||||
pelaalsqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAsl

CLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSP
||||||||...|| .|....||.|||||||.|||.|||.|| ||.....|.|..||
claylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgkssvkmvdsp

subfamily_DSP1_pd Subfamily DSP1 18-162 1.8e-41 135.9 In-house 13-158 (163) alignment
Range on Protein: 18-162
Range on HMM: 13-158/163.0
SIYSF-SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASL
..|    .|.  |.|     | .. .|.|..||||.|.| |. ||| .  .| |... | ..  ..  |... . |...   .|. |.|| ||.|||..|
klydPvekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstl

CLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFN
||||||| . .|| .|....|.||.||.|| ||  ||.||| || .
claylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekklll

0044763 (Phosphotyrosine protein) phosphatases II 11-165 5e-38 125.8 In-house 12-175 (178) alignment
Range on Protein: 11-165
Range on HMM: 12-175/178.0
SQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEG---------IQYIKVPVTDARDSRLYDFFDPIADLIHTID-MRQG
 .|..    . .|.|.  |.|..  .|.|. ||  . ||.||| . |. . |..          |||...|. |  .  |...|. . ..|...   ..|
leglersdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekgg

RTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPiIRPNNGFWEQLINYEFKLFNNNT
..| ||.|||.||..|..|||||....|| .|  . ..||| | || |...||. .| .|.....
pvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkesd

subfamily_DSP19_pd Subfamily DSP19 22-160 1.6e-37 123.2 In-house 12-150 (152) alignment
Range on Protein: 22-160
Range on HMM: 12-150/152.0
FSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYL
 .... .|.|.   .|.||  |....|| |.| ...|.||| . ..| .... |  . .| .... . | |.     .|. |.|| ||||||||. .|||
vgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviayl

MKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL
|| ...|| .| .  .. || |.||.||..|| .|| .|
mkkeelsleealelvrearpcikPneGFikqLkeyeael

subfamily_DSP10_pd Subfamily DSP10 21-165 1.7e-37 122.7 In-house 13-158 (159) alignment
Range on Protein: 21-165
Range on HMM: 13-158/159.0
SFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFE-GIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLA
  ||.   ||| ... |.|. .|   .|||..|   .| | | | ...| ..||.|.    |   |.   . |. .  .. | |.||.||.||||.. .|
pasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNT
||||. ..|| ||. . |..|||| || .|  ||...| .| ....
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnkska

PTPc_motif_SM00404 22-158 3.6e-37 122.4 In-house 2-139 (140) alignment
Range on Protein: 22-158
Range on HMM: 2-139/140.0
FSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN-VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
 |.|.. |.|..  .|... ||....||...|.. ||..    .|.|....|. | . . | ...| ..| |...  ..|. | ||.|||||||.|..||
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
||.|...|| .|    |.|||||.|| .|..|||.|| 
lmryrqlslaeayefvkerRpiispnlnfvrqLieyek

0048076 (Phosphotyrosine protein) phosphatases II 20-161 9.8e-34 111.4 In-house 2-143 (145) alignment
Range on Protein: 20-161
Range on HMM: 2-143/145.0
YSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLA
| .|.|. .|.|..  .|.|  || .. ||...| . |  ... .||||. .|. |     |..... . ..|...  . |..| ||.|||.|...|..|
ywpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa

YLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLF
|||.....|| .|  . .|.||.. || |....|. .| .|.
ylmlllgvsleealelvrsqrpgavpnpgqlrflyefelell

DSPc Dual specificity phosphatase, catalytic domain 29-158 1.6e-33 110.4 Pfam-A 1-132 (133) alignment
Range on Protein: 29-158
Range on HMM: 1-132/133.0
LFLSNGVAANdKLLLSSNRITAIVNASVEVVNVFF---EGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYH
|.|..  .|. . ||. . ||...|.. || | ..   . |.|...|| | ... . .... . . |.... .... | ||.||.||||.|..|||||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

SMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
..|| .|    |.||..|.|| ||. ||..|| 
nlslneAyefvkerrskispnagflrqLleyer

DSPc Dual specificity phosphatase, catalytic domain 29-158 1.6e-33 110.4 In-house 1-132 (133) alignment
Range on Protein: 29-158
Range on HMM: 1-132/133.0
LFLSNGVAANdKLLLSSNRITAIVNASVEVVNVFF---EGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYH
|.|..  .|. . ||. . ||...|.. || | ..   . |.|...|| | ... . .... . . |.... .... | ||.||.||||.|..|||||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

SMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
..|| .|    |.||..|.|| ||. ||..|| 
nlslneAyefvkerrskispnagflrqLleyer

0041856 (Phosphotyrosine protein) phosphatases II 22-166 6.2e-33 109.3 In-house 19-178 (182) alignment
Range on Protein: 22-166
Range on HMM: 19-178/182.0
FSQITRSLFLSNGVA--------------ANDKLLLSSNRITAIVNASvEVV----NVFFEGIQYIKVPVTDARDSRlydfFDPIADLIHTIDMRQGRTL
...|. .|.|..  |              |..  .| ...||.|||.. |.     ..  .||||...|. |         .| . |.|...  ..|..|
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvl

LHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRP--IIRPNNGFWEQLINYEFKLFNNNTV
 ||.|||.|...|..|||||....|| .|  . .||||  .|.|| .|..||. .|..|......
VHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllkktrp

0045098 (Phosphotyrosine protein) phosphatases II 4-163 1.9e-32 108.2 In-house 4-274 (278) alignment
Range on Protein: 4-163
Range on HMM: 4-274/278.0
SASSFSSSQGVQQPSIYSFSQITRSLFLSNGV-----------------------------------------AANDKLLLSSNRITAIVNAS-------
 ||. ..... .... ...|.|| .|.|.|.                                          .|..  .| ...||.||..        
lasldlllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgr

---------------------------------------------VEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDM-------------
                                              .  . ... ..|. .|  .. .. ....|. . . |.                 
ekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssllll

-RQGRTLLHCMAGVSRSASLCLAYLMKYH---SMSLLDAHTWTKSRRPI-IRPNNGFWEQLINYEFKLFNN
 ..|..| ||.|||.|.. |..||||...    ..||.| .. .|.||. . .| .....|. .. .|...
dsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelllr

subfamily_Slingshot_pd Subfamily Slingshot 22-160 2.5e-32 105.6 In-house 19-157 (169) alignment
Range on Protein: 22-160
Range on HMM: 19-157/169.0
FSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYL
 |.|   ..|     | .   |..|... |.| . |. | | | ..|... | |  .. |.....   . |..   .. . |.||  |||||||  .|| 
askifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviaya

MKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL
|| ...|| .|... |.|| .|.||.||..|| .||  |
mkeyglsleealeyvkerrsvikPnkgflkqleeyeGil

subfamily_DSP8_pd Subfamily DSP8 22-163 3.5e-32 105.2 In-house 15-157 (159) alignment
Range on Protein: 22-163
Range on HMM: 15-157/159.0
FSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN-VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
  .|.. |.|   . . .. ||| . |. ..||| . ..  ...  ....||| |  | .| ..||   . |  .   .|| |.|..|| ||||.. .||
ptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiay

LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNN
.||. .||| .|... |..|| | ||  | .||..|| .| ..
imktlemsldeayrfvkekrptispnlnflgqLleyekelkll

0048179 (Phosphotyrosine protein) phosphatases II 21-158 4e-32 106.3 In-house 3-142 (144) alignment
Range on Protein: 21-158
Range on HMM: 3-142/144.0
SFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFE--GIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCL
 .|.|. .|.|..  .|.|  || .. ||...| . |  . |.|  ||||...|. |     |..... . ..|...  . |..| ||.|||.|...|..
npseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlva

AYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
|||||.. .|| .|  . .||||.. || |....|..|| 
aylmkklglsleealalvrsrrpgavpnpgqlrfLleyek

subfamily_DSP15_pd Subfamily DSP15 22-163 4.1e-31 102.1 In-house 2-142 (151) alignment
Range on Protein: 22-163
Range on HMM: 2-142/151.0
FSQITRSLFLSNGVAANDKLLLSSNRITAIVNASvEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYL
 |.. . |.|.|   ..|. ||. ..|| |.. . .  . ... |.|  ....|. .  |  ||.   ..||.  ....  |.||.||||||. |. |||
iskvlpglylgnfrdskdeelLkeknithilsvh.dnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYl

MKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNN
|   ...  || .  | .| .  || || .|| .|| .  ..
mtvtelnwrdalevikaaRsvanPnfGfkrqlkeyektklke

0049772 (Phosphotyrosine protein) phosphatases II 61-188 1.6e-30 102.4 In-house 174-302 (314) alignment
Range on Protein: 61-188
Range on HMM: 174-302/314.0
VFFE--GIQYIKVPVTDaRDSRLYDFFDPIADLIHTIdMRQGRTLLHCMAGVSRSAS-LCLAYLMKYHSMSLLDAHTWTKSRRPiIRPNNGFWEQLINYE
 .||  ||.|. .||.|  .  | ..|| . ..|..   ..|..| ||.||..|... ...|||||.. .|| .|  . ...|| |.|| ||.|||..||
elferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqye

FKL-FNNNTVRMINSPVGNIPDIYEKDLRMMI
|.| . .. .... .  . ........|...|
filealleylkflkkfyeyleenlldglqlli

subfamily_DSP3_pd Subfamily DSP3 21-162 2.9e-30 99.0 In-house 10-159 (162) alignment
Range on Protein: 21-162
Range on HMM: 10-159/162.0
SFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVE-V-----VNVFFE--GIQYIKVPVTDARDSRLYDFFDPIADLIH-TIDMRQGRTLLHCMAGVS
.. ... .|....  .|.||  |    || ..||.   .      . |..  .|.|. ..|.|.  . |  .|.. |. |. ... ..|. |.||..|||
evdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvs

RSASLCLAYLMKYHSMSLLDAHTWTKSRRPIiRPNNGFWEQLINYEFKLFN
||| | ||||| ...|.| .| .  ...| | .||.|| .||.... .| .
RsatlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeelkr

subfamily_DSP6_pd Subfamily DSP6 22-160 9.9e-30 97.1 In-house 14-154 (158) alignment
Range on Protein: 22-160
Range on HMM: 14-154/158.0
FSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFE--GIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLA
  .|.  |.| .  .|..  .|.  .|  ..|   .. |.| |   ..| ..|..|     |  ||    ..|     ..   |.||.||.|||  ..||
pveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtla

YLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL
||||.. .|| ||. . |.|.. | ||  | .||...| .|
ylmkklalslndaydlvkkrksnisPnfnfmgqlldfersl

0037934 (Phosphotyrosine protein) phosphatases II 21-161 4.5e-29 97.1 In-house 38-242 (243) alignment
Range on Protein: 21-161
Range on HMM: 38-242/243.0
SFSQITRSLFLSNG--------VAANDKLLLSSNRITAIVNASVEV---------------------------------------------VNVFFEGIQ
.....|. |....|        ..|..  .| ...||.||.   .|                                              ......|.
nliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvih

YIKVPVTD----ARDSRLYDFFDPIADLIHT-----IDMRQGRTLLHCMAGVSRSASLCLAYLMKYH-SMSLLDAHTWTKSRRPI-IRPNNGFWEQLINY
|  .|. |       . |.||.| . . |.       . ..|..|.||.|||.|.. |..||||... ...|..|  . ...||  . .. .....|. .
yhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyea

EFKLF
. .|.
llell

subfamily_MKPLT_pd Subfamily MKPLT 18-158 1.1e-28 93.8 In-house 18-158 (164) alignment
Range on Protein: 18-158
Range on HMM: 18-158/164.0
SIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLC
 ||    .   |.| |.  |... .|    || ||| | |  . | . ..| .| | |  |..| .|.. .|...       || |.||  |.|||.|  
kiypsvvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvt

LAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
.|.|.|..   | .|. . | || |..|| ||  || ..| 
vafLikskgwtlkeayeylkerrsivapnrGflkqlakfee

subfamily_MKPLV_pd Subfamily MKPLV 18-158 1.1e-28 93.8 In-house 18-158 (164) alignment
Range on Protein: 18-158
Range on HMM: 18-158/164.0
SIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLC
 ||    .   |.| |.  |... .|    || ||| | |  . | . ..| .| | |  |..| .|.. .|...       || |.||  |.|||.|  
kiypsvvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvt

LAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
.|.|.|..   | .|. . | || |..|| ||  || ..| 
vafLikskgwtlkeayeylkerrsivapnrGflkqlakfee

0043147 (Phosphotyrosine protein) phosphatases II 25-161 1.7e-28 94.9 In-house 22-161 (172) alignment
Range on Protein: 25-161
Range on HMM: 22-161/172.0
ITRSLFLSNGVAANDKLLLSSNRITAIVNASvE----VVNVFFEGIQYIKVPVTDARDSrLYDFFDPIADLIHT--IDMRQGRTLLHCMAGVSRSASLCL
.   ... .   | .  .| .. ||.|||.  |      ... .||||. .|. |     | .... . ..|..  .  ..|..| ||.|||.|.. |..
fiatqgplrntladfwrmlkelgithivnlt.ellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlva

AYLMKyHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLF
||||. ...||..|  . ...||.. .| ... .|  .| .|.
aylml.lglsleeavalvrekRpgavqnpsqyrflyyfeklll

subfamily_LRR-DSP_pd Subfamily LRR-DSP 23-164 1.8e-28 93.4 In-house 121-262 (263) alignment
Range on Protein: 23-164
Range on HMM: 121-262/263.0
SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKV-PVTDARDSRLYDFFDPIADLIHTiDMRQGRTLLHCMAGVSRSASLCLAYL
..|   |||    .||.| .| .. .| |. |  ..  .| .  .|. .  . |. .  .. .|. .  .|.    ..|  |.|| ||||||..| ..||
deiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafiee.GrkkGGvlvhcraGvsrsstlvisyl

MKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNN
||.... . .|   ....|| |.||.|| .||  || |||  |
mkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklfctn

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 28-157 5.6e-28 91.3 In-house 14-144 (148) alignment
Range on Protein: 28-157
Range on HMM: 14-144/148.0
SLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFF-EGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHS
 ||| .   | |   |    .|.||||. |  |..   ||.|..|.. |  .  |  .|..|.. ..    . .| |.|.  |||||. | |..|.... 
fLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkr

MSLLDAHTWTKSRRPIIRPNNGFWEQLINYE
.|| .|    ||.|. ..||.|| .|| ..|
vslkealalvkskrryvdpnlgfLkqLaele

PTEN_1 16-163 8.6e-28 92.5 In-house 42-194 (196) alignment
Range on Protein: 16-163
Range on HMM: 42-194/196.0
QpsiysfsQITRSLFLSNGVAA-NDKLLLSSNRITAIVNASVEVVN---------VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDM--RQGRTL
|       .|  .|.. .   . .|.  | .. ||..|| | |  .          | .|..|...|..|   . |  .|| ....|. .    ...  |
q.......eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVl

LHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNN
 || ||..||. .. ||||... ..  .|  . ...|| ..||....|.|..|. .|...
VHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae

subfamily_DSP12_pd Subfamily DSP12 23-158 2.5e-27 90.2 In-house 3-141 (155) alignment
Range on Protein: 23-158
Range on HMM: 3-141/155.0
SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIK---VPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLA
|.|.  |.|..  |.... ||..  ||...    | .. . . .....   ....|  .  . ...| . | |.    ..|  | ||.||||||.....|
srilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviA

YLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEF
||||.. .|| .|.   |. .| |.||.|| |||  .| 
YlmkkeklslekAlklvkekkpeiepNegFleQLklfek

0049260 (Phosphotyrosine protein) phosphatases II 23-157 5.9e-26 86.4 In-house 9-146 (152) alignment
Range on Protein: 23-157
Range on HMM: 9-146/152.0
SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN---VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHT-IDMRQGRTLLHCMAGVSRSASLCL
 ...  ... .  .|... .| .. ||.||.   .. .    . ..|||. .|. |     | .... . ..|.  .  ..|..| ||.|||.|.. |..
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlva

AYLMKyHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYE
||||. . .||..|  . ...||.. || |....| ..|
aylml.lgvsleeavalvrekRpgavpnpgqlrflyefe

0040439 (Phosphotyrosine protein) phosphatases II 36-163 8.1e-26 86.6 In-house 67-248 (249) alignment
Range on Protein: 36-163
Range on HMM: 67-248/249.0
AANDKLLLSSNRITAIVNASVEVVN-------------------------------------------VFFEGIQYIKVPVTDARDSRLYDFFDPIADLI
 ...  .|  ..||.||... .| .                                            . | ...  ...||  |  . ..|... |.|
vedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfi

HTIDM------RQGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNN
. ..       ..|..| ||.|||.|.. ...||||     |.. ..|..|  . .|.|| . .| .....|......|...
eavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelllk

0046846 (Phosphotyrosine protein) phosphatases II 20-163 8.3e-26 86.2 In-house 10-175 (176) alignment
Range on Protein: 20-163
Range on HMM: 10-175/176.0
YSFSQITRSLFLSNGV----------AANDKLLLSSNRITAIVNASVEV-------VNVF----FEGIQYIKVPVTDARDSRLyDFFDPIADLIHTIDMR
.....|. .|.|..             |..  .| ...|||.||   ||        | .     .||||. .|. |     | . .. . ..|..   .
ldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealke

QGRTLLHCMAGVSRSASLCLAYLMKY-HSMSLLDAHTWTKSRRP-IIRPNNGFWEQLINYEFKLFNN
 |..| ||.||..|.. |..|||... . .|...|  . ...||  . .. .....|  .| .|...
ggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefellllkk

0051082 (Phosphotyrosine protein) phosphatases II 18-156 4.9e-25 83.3 In-house 4-149 (151) alignment
Range on Protein: 18-156
Range on HMM: 4-149/151.0
SIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEV-----VN-VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMR-QGRTLLHCMAGV
... ||..|  |..|.|  | .  || .. |..|||   |.      . .  .||... .|..|  |  | ..|| ...... ..   .| .| ||.||.
dyinfsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGk

SRSASLCLAYLMKyHSMSLLDAHTWTKSRRP-IIRPNNGFWEQLINY
.|.. |...|||. . .|| .|  . ...|| ...||..|. ||. .
gRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal

0036282 (Phosphotyrosine protein) phosphatases II 20-160 1.1e-24 82.5 In-house 10-169 (174) alignment
Range on Protein: 20-160
Range on HMM: 10-169/174.0
YSFSQITRSLFLSNGVAAnDKLLLSSNRITAIVNASVEVVNV---------------FFEGIQYIKVPVTDARDSRLYDfFDPIADLIHTIDMR--QGRT
 ..| ||. |....| .| .  .| ...||..|.   |. .                  .||||...|. |     |   .. . ......  .  .| .
ldlsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpv

LLHCMAGVSRSASLCLAYLMKYHSM-SLLDAHTWTKSRR---PIIRPNNGFWEQLINYEFKL
| ||.|||.|.. |..||||... . || ||  . ...|   | . .. .....|  .| .|
lVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll

0045450 (Phosphotyrosine protein) phosphatases II 43-163 2.7e-24 81.9 In-house 127-306 (307) alignment
Range on Protein: 43-163
Range on HMM: 127-306/307.0
LSSNRITAIVNASVEVVN-----------------------------VfFEGIQYIKVPVTDA-----------------RDSRLYDFFDPIADLIHTID
|  ...|.||. . .| .                             .  .|... ...|||                   |  . ..|... |.|. ..
lweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevr

M------RQGRTLLHCMAGVSRSASLCLAYLMKYHS--------MSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNN
       ..|..| ||.|||.|......||||...         ..||.|  . ...|| . .| .....|......|...
kaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelllk

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 26-160 4e-24 78.7 In-house 7-152 (154) alignment
Range on Protein: 26-160
Range on HMM: 7-152/154.0
TRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEG---------IQYIKVPVTDARDSRLYDFFDPIADLIHT-I-DMRQGRTLLHCMAGVSRSA
.  |..|   || .||.|  ..|. |.| .. . |.| .          |.|... . |  .  . . .|   ..|.  |  ..... |.|. .||||||
aiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsa

SLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL
.| ..|||.  ..||  |    |. |.||.||.|| .||  .| .|
allisylmdklkislslalellkdsryiikPnqGflkqleifekel

0042113 (Phosphotyrosine protein) phosphatases II 22-162 1.2e-23 79.2 In-house 47-244 (245) alignment
Range on Protein: 22-162
Range on HMM: 47-244/245.0
FSQITRSLFLSNGVAANDKL----LLSSNRITAIVNASVEV----------------------------------------------VNVFFEGIQYIKV
...||. .....| ....      .| ...||.||. . |.                                               .  .|.|.|  .
gyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhyl

PVTDARDSRLYDFFDPIADLIHTIDM--RQGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFN
|. |     | . .. . ......    ..|..| ||.|||.|.. ...||||     |.. .|| .|  . .|.|| .... .....|. ....|..
pwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallellk

0036941 (Phosphotyrosine protein) phosphatases II 48-171 1e-22 76.3 In-house 103-287 (297) alignment
Range on Protein: 48-171
Range on HMM: 103-287/297.0
ITAIVNASVEVVNVFFEG----------------------------------------------------IQYIKVPvtdarDSRLYDFFDPIADLIHTI
.| ||. . .| . .                                                       ..|.. |     |  . . .... |.|. .
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwp.....dhgvpespaslldfielv

DM------RQGRTLLHCMAGVSRSASLCLAYLM--------KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINS
.       ..|..| ||.|||.||.....|.||        |.. ...|.|  . ...|| . .. .....|. ....|........  .
rkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepll

0040438 (Phosphotyrosine protein) phosphatases II 45-166 3.1e-22 74.7 In-house 108-281 (317) alignment
Range on Protein: 45-166
Range on HMM: 108-281/317.0
SNRITAIVNASVEVVN----------------------------VfFEGIQYIKVPVTDA----------------RDSRLYDFFDPIADLIHTIDMR--
 ...| ||.   .. .                            .  .||.. ...|.|                  |  . . .|.. |... ..    
eqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale

--QGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTV
  .| .| ||.|||.|......||||     |.. ... .|  . ...|| . .. .....|. ......... .
dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrklt

0039614 (Phosphotyrosine protein) phosphatases II 47-163 4.4e-20 67.8 In-house 125-291 (297) alignment
Range on Protein: 47-163
Range on HMM: 125-291/297.0
RITAIVNASVEVVN--------------------------------------------VFFEGIQYIKVPvtdarDSRLYDFFDPIADLIHTIDM-----
..|.||.   .| .                                             .   .||.. |     |    . .. . .... ..      
gvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwp.....dhgvppslellleflelvrealael

-RQGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNN
 ..|..| ||.|||.|......||||     |.. ...|.|  . ...|| .... .....|......|...
pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr

subfamily_MSG5_pd Subfamily MSG5 62-163 2.9e-19 62.8 In-house 64-163 (165) alignment
Range on Protein: 62-163
Range on HMM: 64-163/165.0
FFEGIQYIKVPVTdaRDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLF
    ..| ..  .   ||..   .  .. .||.   .. . |.||  |.|||||| .||.|||...|| ||.   ||.   | |. |.  ||...|  | 
lvpavkyyhiewe..hdskivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewevals

NN
..
kk

0051429 (Phosphotyrosine protein) phosphatases II 26-163 5.5e-19 64.3 In-house 20-227 (272) alignment
Range on Protein: 26-163
Range on HMM: 20-227/272.0
T-RSLFLSNGV---AANDKLLLSSNRITAIVNASVEVV------NVFFEGIQYIKVPVTDARDSRLYDFF------------------------------
  . |..|.|     |.|   | ...|..||.   |.         . .||.|. .|. |  . .   ..                              
kpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagea

------------------DPIADLIHTIDMrQGRTLLHCMAGVSRSASLCLAYLMKyHSMS--------------LLDAHTWTKSRRPIIRPNNGFWEQL
                  ... .|.. .   .|. | ||.||..|.. .....|.  . .|              |..|  . ...|| .... .....|
revmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylfl

INYEFKLFNN
 ... .|...
yeallellrs

0038934 (Phosphotyrosine protein) phosphatases II 64-162 9.7e-19 63.2 In-house 78-178 (194) alignment
Range on Protein: 64-162
Range on HMM: 78-178/194.0
EGIQYIKVPVTDARDSRLYDFFDPIADLIHTID--MRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLF
 ||.|.| |. |   .  ..  . . ||....     .|  . ||.||..|.. |. |||.... ||. .|  . ...|| . || ...|.|  .   |.
agieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykelr

N
.
k

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 29-160 1.4e-18 60.4 In-house 6-141 (145) alignment
Range on Protein: 29-160
Range on HMM: 6-141/145.0
LFLSNGVAANDKLLLSSNRITAIVNAS----VEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKY
|.   .. |||  .|    |. ||| .    |   ..  | |. . .   | .   | . || ..|.|          ..||||||||| .. .|.||||
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

HSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL
 .|.| .|    .|.|    ||  |  .|.| | .|
cnmtlseaarqvrsnrllaypnvtflknllnlekql

subfamily_STYX_pd Subfamily STYX 43-168 2.4e-18 59.8 In-house 35-165 (166) alignment
Range on Protein: 43-168
Range on HMM: 35-165/166.0
LSSNRITAIVN----ASVEVV-NVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTK
| .. || ||        ...   | . ..|. . |.|.    .  ..  . ..| .   . |. |.|  ||.||||.| .||.|. . .   .|... .
lkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvq

SRRPIIRPNNGFWEQLINYEFKLFNNNTVRM
 ||  | ||.|| .|| .||   . . |...
errfcinpnegfvsqlkeyeaiylakltikl

subfamily_STYXL1_pd Subfamily STYXL1 24-162 8.2e-18 58.1 In-house 14-155 (157) alignment
Range on Protein: 24-162
Range on HMM: 14-155/157.0
QITRSLFLSNGVAANDKLLLSSNRITAIVNASVE---VVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
 .   |.| |   | .. .    .. | || | .   ...   .  . ....| |  .. | .... . ..|..   ..   |.    |.||||.. .||
vlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiay

LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFN
|| .. ..| .|..  |  .. ..|| .| ||| ..| .|..
lmyskkitlkkaykylkkCkenvkPnrafveqlseWekqllg

0043336 (Phosphotyrosine protein) phosphatases II 61-159 5.9e-17 57.5 In-house 173-275 (278) alignment
Range on Protein: 61-159
Range on HMM: 173-275/278.0
VFFEGIQYIKVPVTDARDsRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLIN
 .  ...|...|  .. .  | ...| . .... .. ..| .| ||.|||.|.. ....||.     |.. ..|..|  . ...|| . ..  ....|..
rtvthyhylgwpdhgvpe.slsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflye

YEFK
... 
alle

subfamily_PTPMT1_pd Subfamily PTPMT1 64-160 4.6e-14 47.2 In-house 72-168 (171) alignment
Range on Protein: 64-160
Range on HMM: 72-168/171.0
EGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL
.|.........|  ..   .      ..|. .  .. |  .|| || .|||.|  .|||| . .|. .|..  |..|.||| ..  |..| .|| ||
lgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekl

0047943 (Phosphotyrosine protein) phosphatases II 76-155 5.6e-14 47.7 In-house 176-266 (273) alignment
Range on Protein: 76-155
Range on HMM: 176-266/273.0
ARDSRLYDFFDPIADLIHTIDM------RQGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLIN
  |    . .... ..|. ..       ..| .. ||.|||.|........|.     |.. ...|.|  . .|.|| . ..  ....|..
wpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflye

0051299 (Phosphotyrosine protein) phosphatases II 73-146 4.4e-12 41.5 In-house 189-271 (288) alignment
Range on Protein: 73-146
Range on HMM: 189-271/288.0
VTDARDSRLYDFFDPIADLIHTIDMR----QGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPN
.|.  |    | .... |... ..      .| .. ||.|||.|.. .....|.     | . ...|.|  . ...|| . ..
ytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqt

0046845 (Phosphotyrosine protein) phosphatases II 66-143 4.9e-11 38.0 In-house 170-256 (284) alignment
Range on Protein: 66-143
Range on HMM: 170-256/284.0
IQYIKVPvtdarDSRLYDFFDPIADLIHTIDMR------QGRTLLHCMAGVSRSASLCLAYLMKYH--------SMSLLDAHTWTKSRRPII
..|.. |     |    . .... .......        .| .. ||.|||.|.. .....|....         ...|.|  . ...||  
fhytswp.....dhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgm

0050432 (Phosphotyrosine protein) phosphatases II 80-146 5.3e-11 37.9 In-house 211-284 (308) alignment
Range on Protein: 80-146
Range on HMM: 211-284/308.0
RLYDFFDPIADLIHTIDMR--QGRTLLHCMAGVSRSASLCLAYLM-----KYHSMSLLDAHTWTKSRRPIIRPN
   . .... |... .. .  .| .. ||.|||.|.. .....|.     | . .....|  . ...||   ..
gvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqt

0048567 (Phosphotyrosine protein) phosphatases II 77-157 1.7e-10 35.5 In-house 52-135 (157) alignment
Range on Protein: 77-157
Range on HMM: 52-135/157.0
RDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGV---SRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYE
  ..||.|.  . .... .... ..  .|| ||    .|.| |. .||.......  .|  . .  || . |    .  | .|.
nlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslyn

subfamily_Laforin_pd Subfamily Laforin 64-143 1.5e-07 24.5 In-house 75-154 (183) alignment
Range on Protein: 64-143
Range on HMM: 75-154/183.0
EGIQYIKVPVTDA-RDSRLYDFFDPIaDLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII
||. || .|. |   .||.  . . .  |.|..  .  .  .|| ||| ||...   .|.     ||        ..||..
eglayiwlptedlstesrvenlpqav.yllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv

PTPc_DSPc_SM00012 69-125 9.4e-07 24.4 In-house 13-65 (105) alignment
Range on Protein: 69-125
Range on HMM: 13-65/105.0
IKVPVTDardsrlydffDPIADLIHTIDMR------QGRTLLHCMAGVSRSASLCLAYLMKYH
 .|| .           |.| .|.. ..        .. ...|| |||.|.. .......  .
hgvPees..........dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqq

subfamily_CDC14_pd Subfamily CDC14 91-141 1.1e-06 22.8 In-house 255-305 (328) alignment
Range on Protein: 91-141
Range on HMM: 255-305/328.0
LIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRP
... ..  .|   .|| ||. |  .|  .|||| . ..  .| .| .  ||
fleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrP