Gene DUSP13 in Homo sapiens

Synonym: BEDP, DUSP13A, DUSP13B, MDSP, SKRP4, TMDP, RP11-487I5.6, DUSP13

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP3
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP025_AA protein Get Run
HsapP025_AA_262-411 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP3_pd Subfamily DSP3 258-413 1.1e-72 236.9 In-house 4-160 (162) alignment
Range on Protein: 258-413
Range on HMM: 4-160/162.0
QAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKF-QVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVH
.... ...|||.|.|..||...|.||||| .||||||.|||.|.| .|||||.||......|.|.|.||.| ||||.|| ..|..|..||| ..|.||||
erllskevdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvh

CAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
|..|||||||||||.|||...|||||||.||...|.|.||.|||.||. ||..| |.
cvvGvsRsatlvlayLmirrkmtlveairtvrkkReilPneGFlkqLaeldeelkrk

0044763 (Phosphotyrosine protein) phosphatases II 259-410 5.2e-40 132.3 In-house 17-170 (178) alignment
Range on Protein: 259-410
Range on HMM: 17-170/178.0
AATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKF--QVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVH
..  ....|..| |.||....|.|.  | .|||||.|| .  .   .... ..........|. |  .|.. .||. .|| . ..|..||. ..|.||||
rsdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVH

CAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL
| .||.||.|||.|.||.. ...| |||. |...|.|.|| |.||||. .. ||
CsaGvgRsgtlvaaylmkklglsleeaielvrerRpivpnpgqlrqLyefelrl

subfamily_DSP14_pd Subfamily DSP14 262-410 4.2e-35 115.0 In-house 4-144 (157) alignment
Range on Protein: 262-410
Range on HMM: 4-144/157.0
LNHIDEVWPSLFLGdAYAARDKSKLIQLGITHVVNAAAgkfQVDTgaKFYRGMSleYYGIEADDNPFFDLSVYFLPVARYIRAAlSVPQGRVLVHCAMGV
|... .. |||||. ..||..|..| . .||...|..    .. .  . .....  .  . ..|||  .|. .| .|| .|... .  .|..||||..||
laalsqitpsLfls.gvaalskellkkkkitliinvtv...elpn..tklkdie..rvkvpveDnpeaklakhfdevadkieev.kkkggktlvhCvaGv

SRSATLVLAFLMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLDNRL
||||.|.||.||  |...| || ..|...|. |.||.|| .||. ....|
SRSAslclaylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkkl

subfamily_DSP1_pd Subfamily DSP1 263-412 9e-33 107.6 In-house 16-158 (163) alignment
Range on Protein: 263-412
Range on HMM: 16-158/163.0
NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAgkfQVDtgaKFYRGmSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVS
. . .. . |.|| .. | ... | .||||...|...   ..|   ....   .||. .. .|.|  |.|..| .|  .| .. .  .|.||.||..|.|
dPvekildfLylGsetvasnleiLkslgitailnvsk...eld...nvfed.lfeYkklkleDspkadislvfeeviefidevkkk.nGkvlihCqaGis

RSATLVLAFLMICENMTLVEAIQTVQAHRNI-CPNSGFLRQLQVLDNRLGR
||.||.||.||  ....| || . |. .|.|  || || .||   ...|..
RsstlclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekklll

0041856 (Phosphotyrosine protein) phosphatases II 264-411 3.9e-31 103.4 In-house 18-173 (182) alignment
Range on Protein: 264-411
Range on HMM: 18-173/182.0
HIDEVWPSLFLGDAYA--------------ARDKSKLIQLGITHVVNAAagkfQVDTGAKFYRGMSLEYYGIEADDNPFFDlsvyFLPVARYIRAALSvP
..|.....|.||. .|              |..   | .||||..||..     .   ....  . ..|. .  .|.. .|    .  . ..|...|. .
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt....eelywpellerlgiqylylpwpDhgvpd....ldelldfieevle.e

QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRN---ICPNSGFLRQLQVLDNRLG
.|.||||| .||.|..|||.|.||.. ...| ||...|. .|.   |.|| .|..||..|. .|.
ggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll

0048179 (Phosphotyrosine protein) phosphatases II 264-409 1.4e-30 101.3 In-house 3-143 (144) alignment
Range on Protein: 264-409
Range on HMM: 3-143/144.0
HIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKfyrgmSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSvPQGRVLVHCAMGVSR
...|..|.|.||. ..|.|   | .||||.|.| . .  . . .        ..|. .  .|.. .||. ..| . ..|..||. . |.||||| .||.|
npseilpglylgslptaldlellkklgittvinlteeyepeflere.....giqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgR

SATLVLAFLMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLDNR
..|||.|.||......| ||.. |...|  ..|| |.||.|. ....
tgtlvaaylmkklglsleealalvrsrrpgavpnpgqlrfLleyekl

0048076 (Phosphotyrosine protein) phosphatases II 265-408 1.5e-30 101.2 In-house 4-140 (145) alignment
Range on Protein: 265-408
Range on HMM: 4-140/145.0
IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAaagkfqvDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPqGRVLVHCAMGVSRS
..|..|.|.||. ..|.|   | .||||.|.|         .  ...  . ..|. .  .|.. .||. ..| . ..|..||. . |.||||| .||.|.
pseilpglylgslptaldlellkdlgittvlnl.......tselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRt

ATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVLDN
.|||.|.||......| ||.. |...| ...|| |.||.|. .. 
gtlvaaylmlllgvsleealelvrsqrpgavpnpgqlrflyefel

subfamily_DSP19_pd Subfamily DSP19 264-408 4.6e-30 99.0 In-house 11-148 (152) alignment
Range on Protein: 264-408
Range on HMM: 11-148/152.0
HIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVdtgakFYrgMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPqGRVLVHCAMGVSR
.. || |.|.||   .| ||..| . .|||..| |.|  .|     |     ..|  ||  |.|  ||. |.  .  .|. |.|   |.|||||  ||||
evgeveprlylgsqdvaadkeilkekkitHilnvatgvpnv.....fp..kdftylsieilDlpetdllsylkealdFieearskd.gavlvHCnAGvSR

SATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVLDN
||..|.|.||  |...| ||...|...| .|.||.||..||. ...
sasvviaylmkkeelsleealelvrearpcikPneGFikqLkeyea

PTPc_motif_SM00404 266-407 4.3e-29 96.2 In-house 3-138 (140) alignment
Range on Protein: 266-407
Range on HMM: 3-138/140.0
DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKF-QvdtgakfYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAAlSVPQGRVLVHCAMGVSRS
 .. | |.|| ...| .. .| .||||||.|..  .  .       .   . ..  |. |||   .|| |.  |...|..|    .|.|||||..|||||
srilphlylgskskaqnpallkklgithvinvteevslt.......kensgfqilqiplddnekdklskyldkvldfiena.ekkggkvlVHCqaGvSRS

ATLVLAFLMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLD
|||..|.||  ....| ||.. |.  |. |.|| .|.|||. . 
atliiaYlmryrqlslaeayefvkerRpiispnlnfvrqLieye

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 266-408 9.6e-29 93.8 In-house 8-145 (148) alignment
Range on Protein: 266-408
Range on HMM: 8-145/148.0
DEVWPS-LFLGDAYAARDKSKLIQLGITHVVNAAAgKFQVDTGAKfyrgmSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVSRS
 |.... ||||.   | | ..| .||.|..|||.. . .     .     ..||. .. ||.| .||| .| ... ..| | .   .|||||. ||||||
seikdafLFlGskksaadlealkalgvtrivnatk.erdnaldqr.....gieYlhvaldDkpkedlsaiFediiafvrkakde.GrrvLvhlqmGvsrs

ATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVLDN
. |.|..|.  ....| ||.. |.  |  . || |||.||. |..
salallwlidfkrvslkealalvkskrryvdpnlgfLkqLaeleq

PTEN_1 239-404 1.4e-28 95.1 In-house 14-185 (196) alignment
Range on Protein: 239-404
Range on HMM: 14-185/196.0
ASPYQPPTLASLQRLLWVRQ-AATLNHIDEVWPSLFLGDAYAA-RDKSKLIQLGITHVVNAAAGKFQ--VDTGAKFYRGMSLEYYGIEADDNPFFDLSVY
| | ....|..  . ... . | ... ..|....|..| .  . .|.  | . |||.||| . ..    ..   .... . .||. .. .| .  .||  
alptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslsel

FLPVARYIRAALSVP-QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQ
|  ... | ..|| | .. |||||. |..||.|.| |.|| ....|  ||.. |...| ...|||.....|.
fdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerll

subfamily_DSP12_pd Subfamily DSP12 265-406 1.9e-28 93.8 In-house 2-139 (155) alignment
Range on Protein: 265-406
Range on HMM: 2-139/155.0
IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAagKFQVdTGAKFYRGMSLeYYGIEADDNPFFDLSVYFLPVARYIRAALsVPQGRVLVHCAMGVSRS
.... | |.||.. |. ....| .|.||||.  .  |...    |  .|    .  |...|.|  |.  ..  . ..|  ||   .| |||||..|||||
vsrilpglylggleavqeeellkelkithvlsvi..keel.pehklkkgkvs.tkfiqilDepeediLshldeavdFieeal.eeegavlvHCqagvSRS

ATLVLAFLMICENMTLVEAIQTVQA-HRNICPNSGFLRQLQVL
.|.|.|.||  |.. | .|...|.. ...|.|| |||.||.. 
vtiviAYlmkkeklslekAlklvkekkpeiepNegFleQLklf

0045098 (Phosphotyrosine protein) phosphatases II 253-410 2e-28 95.0 In-house 10-271 (278) alignment
Range on Protein: 253-410
Range on HMM: 10-271/278.0
LLWVRQAATLNHIDEVWPSLFLGDAY-----------------------------------------AARDKSKLIQLGITHVVNAAAGKF---------
||.  .   |....|..|.|.||...                                         .| .   | .||||..|...  .          
llefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqy

------------------------------------QVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSV-------------PQGRV
                                      ... . .    | |....  . | .... .|| . ..||.||..             ..|.|
wpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv

LVHCAMGVSRSATLVLAFLMICE---NMTLVEAIQTVQAHRN--ICPNSGFLRQLQVLDNRL
|||| .||.|..|||.|.||..    ...| ||..... .|.  ...| ...|.|  .  .|
lVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel

0043147 (Phosphotyrosine protein) phosphatases II 264-410 2.7e-28 94.2 In-house 18-160 (172) alignment
Range on Protein: 264-410
Range on HMM: 18-160/172.0
HIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAagkfQVDTGAKFYRGMSLEYYGIEADDNPFFdLSVYFLPVARYIRA-ALSVPQGRVLVHCAMGVS
..|.... ..... . | .   | .|||||.||.     .  . ....  . ..|. .  .|.. . |. ..| . ..|.  ..  |.|.||||| .||.
ipdrfiatqgplrntladfwrmlkelgithivnlt....ellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvg

RSATLVLAFLMIcENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLDNRL
|..|||.|.||. ....| ||...|...|. ...| ...|.|. ....|
Rtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfekll

DSPc Dual specificity phosphatase, catalytic domain 272-407 8.9e-27 88.6 Pfam-A 1-131 (133) alignment
Range on Protein: 272-407
Range on HMM: 1-131/133.0
LFLGDAYAARdKSKLIQLGITHVVNAAAGKFQVdtgaKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAAlSVPQGRVLVHCAMGVSRSATLVLAF
|.|| ...|  ...| .||||.|.|..  . .     ...   . || .|  .|.   ..| ..  . ..|..|    ...|||||..|.||||||..|.
lylgskstas.lalleklgitlvinvtkevpnn....naikkseieylripvedetetkiskeleeavefieka.eqkgkkvlVHCqaGisRSatliiaY

LMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLD
||  .|..| ||.. |.  |. |.|| ||||||  ..
lmktknlslneAyefvkerrskispnagflrqLleye

DSPc Dual specificity phosphatase, catalytic domain 272-407 8.9e-27 88.6 In-house 1-131 (133) alignment
Range on Protein: 272-407
Range on HMM: 1-131/133.0
LFLGDAYAARdKSKLIQLGITHVVNAAAGKFQVdtgaKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAAlSVPQGRVLVHCAMGVSRSATLVLAF
|.|| ...|  ...| .||||.|.|..  . .     ...   . || .|  .|.   ..| ..  . ..|..|    ...|||||..|.||||||..|.
lylgskstas.lalleklgitlvinvtkevpnn....naikkseieylripvedetetkiskeleeavefieka.eqkgkkvlVHCqaGisRSatliiaY

LMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLD
||  .|..| ||.. |.  |. |.|| ||||||  ..
lmktknlslneAyefvkerrskispnagflrqLleye

0049772 (Phosphotyrosine protein) phosphatases II 276-410 1.1e-26 89.8 In-house 156-273 (314) alignment
Range on Protein: 276-410
Range on HMM: 156-273/314.0
DAYAARDKSKLIqlgithvvnaaagkfQVDTGAKFYRGMSLEYYGIEADDnPFFDLSVYFLPVARYIRAAlsVPQGRVLVHCAMGVSRSAT-LVLAFLMI
. . |.|   |                .. . .... .. ..|. |  .| . ..|. .|. . ..|..|   ..|.|||||..|..|..| .|.|.||.
neptaadlellk...............eelydpelferlgikylripvpD.gsaplledfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmk

CENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL
. ...| ||.. |.. | |.|| ||..||. . ..|
llgvsleealedvrlkRpinpnpgfieqleqyefil

0051082 (Phosphotyrosine protein) phosphatases II 264-406 1.3e-26 88.4 In-house 7-149 (151) alignment
Range on Protein: 264-406
Range on HMM: 7-149/151.0
HIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVdTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSR
..  |.. |.....  |..   | .|||...||    .    . ..... ...|.. |  .|.|...|...|  |.......|. ..| ||||| .|..|
nfsyvtgglyrsggpladflellkelgiktivnlrseeerg.ycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgR

SATLVLAFLMIcENMTLVEAIQTVQAHR--NICPNSGFLRQLQVL
..|||...||. ....| ||.. ....|   ..|| .|| ||..|
TGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal

0046846 (Phosphotyrosine protein) phosphatases II 255-405 2e-26 88.2 In-house 2-167 (176) alignment
Range on Protein: 255-405
Range on HMM: 2-167/176.0
WVRQAATLNHIDEVWPSLFLGDAY----------AARDKSKLIQLGITHVVNAAAG----KFQVDTGAKFYRGMSLEYYGIEADDNPFFDLsVYFLPVAR
..|.    ...|.....|.||...           | .   | .||||.|||        ......  . .......|. .  .|.   ||  ..| . .
rlrllgldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllelle

YIRAALSVPqGRVLVHCAMGVSRSATLVLAFLMIC-ENMTLVEAIQTVQAHR--NICPNSGFLRQLQV
.|| ||.   |.||||| .|..|..|||.|.|...  .... ||...|...|  .. .. ...|.|. 
firealkeg.gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflye

subfamily_DSP10_pd Subfamily DSP10 265-412 7.5e-26 84.9 In-house 14-155 (159) alignment
Range on Protein: 265-412
Range on HMM: 14-155/159.0
IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAgkfqvDTGAKFYRgMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVSRS
. .| | ||||..  |.|.. | .|.||.|.| ..     ..  .|.   .|.|  |.. |.   .|. ||     .|  | .  . ||||||  |.|||
asqvlpfLflGsekdaadldaldrlnitavlnvtt.....svPnefee.ealkYkripvsDtskqnlkqyfeealefieearkk.gsrvLvhCqaGisrs

ATLVLAFLMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLDNRLGR
||.|.|.||   |..| .| . |.  |  | || .|. ||  ....| .
atvviaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnk

0049260 (Phosphotyrosine protein) phosphatases II 267-405 1.4e-25 85.1 In-house 10-144 (152) alignment
Range on Protein: 267-405
Range on HMM: 10-144/152.0
EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRgmslEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSAT
|... ...|.  .| ..  | .||||..|.          . ..|     .|. .  .|..  ||| ..| . . |. ..  ..|.|||||  ||.|..|
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi....qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgt

LVLAFLMIcENMTLVEAIQTVQAHRN-ICPNSGFLRQLQV
||.|.||.  ...| ||.. |...|. ..|| |.||.|. 
lvaaylml.lgvsleeavalvrekRpgavpnpgqlrflye

subfamily_DSP15_pd Subfamily DSP15 265-407 2e-25 83.6 In-house 2-136 (151) alignment
Range on Protein: 265-407
Range on HMM: 2-136/151.0
IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAgkfqvdTGAKFYRGmsLEYYGIEADDNPFFDLSVYFLPVARYIRAAlSVPQGRVLVHCAMGVSRS
|..| | |.||.   ..|. .| .  |||...            |. .   .||  |.|.| |  .|| .|    ..| ..  . .. |||||..|||||
iskvlpglylgnfrdskdeelLkeknithilsvhd......nakkllkd..ieYkciaasDtpsaklskffkesvefihkc.RlkeenvlvhClaGvsRs

ATLVLAFLMICENMTLVEAIQTVQAHRNIC-PNSGFLRQLQVLD
.||| |.||   ..   .|.....|.| .  || || |||.. .
vtlvvaYlmtvtelnwrdalevikaaRsvanPnfGfkrqlkeye

0036282 (Phosphotyrosine protein) phosphatases II 264-405 3.1e-25 84.3 In-house 11-164 (174) alignment
Range on Protein: 264-405
Range on HMM: 11-164/174.0
HIDEVWPSLFLGDAYAArDKSKLIQLGITHVVNAAAGKFQV--------DTGAKFYRGMSLEYYGIEADDNPFFDLSVyFLPVARYIRAALSV-PQGRVL
.. ...| |..|.. .| .   | .||||.||.    |            .  .... . ..|. .  .|.  .|||. .| . .... |||  |.| ||
dlsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvl

VHCAMGVSRSATLVLAFLMICENM-TLVEAIQTVQAHR----NICPNSGFLRQLQV
||| .||.|..|||.|.||..  . .||.|...|.. |    ..... ...|.|. 
VHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyy

subfamily_LRR-DSP_pd Subfamily LRR-DSP 266-410 4.9e-24 78.8 In-house 121-258 (263) alignment
Range on Protein: 266-410
Range on HMM: 121-258/263.0
DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAgKFQvdtgaKFYRGmSLEYYGI-EADDNPFFDLSVYFLPVARYIRAALSvpQGRVLVHCAMGVSRS
||. . ||||   .| .|| | .||.||.. | | .|.      ..    . |. | ...| . .|.| .|  .  .|       .| |||||  |||||
deiidklflGgldsannksilkdlgvthillava.dfe.....PlfPk.lfkylsiddiedvdeadisqhfeetnafieeGrk..kGGvlvhcraGvsrs

ATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVLDNRL
.|||...||  ..... ||.  |. .| .| || ||. ||.  .. |
stlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekkl

subfamily_DSP6_pd Subfamily DSP6 267-411 8e-24 77.9 In-house 16-155 (158) alignment
Range on Protein: 267-411
Range on HMM: 16-155/158.0
EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAgkfqvDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVSRSAT
|. | |.|| | .| .   | .|.| .|.| .      .   ||    .|.|. | ..|.   .|. .|    ..|  | |  .  |||||  |.||| |
eilpllylGsakdasnlevlkklkikyvlnvts.....nlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearsk.kskvlvhClaGisrsvt

LVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVLDNRLG
..||.||  ....| .| . |.... || ||  |. ||   ...|.
vtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldferslr

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 272-411 5.7e-23 74.6 In-house 6-142 (145) alignment
Range on Protein: 272-411
Range on HMM: 6-142/145.0
LFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVdtgAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGrVLVHCAMGVSRSATLVLAF
|. | |  |.| . | .|||. .|| |||.      ..  .. |.|   | |.|   .||| .|  |. .|        | |.|||  ||||| |. .||
lyvgsalhandvptlqelgisrivnmaagslva...sqelksesieillitaedlesydlsqhfdevtdfidkgkeegag.vfvhcmagvsrsvtvsvaf

LMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLDNRLG
||   |||| || . |...|   .||  ||..|  |. .| 
lmkycnmtlseaarqvrsnrllaypnvtflknllnlekqlk

0040439 (Phosphotyrosine protein) phosphatases II 267-406 1.3e-21 72.8 In-house 31-241 (249) alignment
Range on Protein: 267-406
Range on HMM: 31-241/249.0
EVWPSLFLGDAYAA------------------------RDKSKLIQLGITHVVNAAAGKFQ--------------------------VDTGAKF------
...|.|||.| . |                         .   | .||||..|..   .                            |.. ...      
silpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtle

----YRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSV-----PQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHR-NICP
    | | |.....|   | | .... .| .. ..|.|....     ..|.||||| .||.|..|...|.||        ...| ||..... .| ....
ltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavq

NSGFLRQLQVL
| ...|.|. .
npeqyrflyea

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 271-408 1.9e-21 70.0 In-house 9-150 (154) alignment
Range on Protein: 271-408
Range on HMM: 9-150/154.0
SLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDT--GAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAAL-SVPQGRVLVHCAMGVSRSATL
 |...   || .| .| .  |....| . |   . |   .    |. .||  .|  |.. ||.   .  .  .|. |. .| ...||||.  ||||||.|
flyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaal

VLAFLMICENMTLVEAIQTVQAHRNIC-PNSGFLRQLQVLDN
....||   ...| .|.. ..  | |. || |||.||.. . 
lisylmdklkislslalellkdsryiikPnqGflkqleifek

subfamily_Slingshot_pd Subfamily Slingshot 263-407 2.2e-21 70.0 In-house 17-154 (169) alignment
Range on Protein: 263-407
Range on HMM: 17-154/169.0
NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAgkfQVDtgaKFYRGmSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSvPQGRVLVHCAMGVS
..  ...  ..||  . | .  .| . |.....| .    ..|   .|. . ..||. |   |..  ||  |.    ..|..| .  . .||||| ||||
dsaskifdhvylGsewnasnleelkengveyilnvtk...eid...nffpe.kfeylnirvydeeetdllkywnetykfiekakk.kgskvlvhckmGvs

RSATLVLAFLMICENMTLVEAIQTVQAHRNIC-PNSGFLRQLQVLD
|||. |.|. |   ...| ||.. |. .|..  ||.|||.||.. .
rsastviayamkeyglsleealeyvkerrsvikPnkgflkqleeye

subfamily_MKPLT_pd Subfamily MKPLT 271-406 9.9e-21 67.9 In-house 28-156 (164) alignment
Range on Protein: 271-406
Range on HMM: 28-156/164.0
SLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQvdtgaKFyrGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVSRSATLVLA
 |.||.|  |...  | .| |||.|| . .| .     .|   .|.||  .. .|..   || ..  .| ..  |.    ||||||| .|.|||..  .|
tlylGnakhatnekvlkdlkithivnvsqekkd.....af..pksveYlqvkvedesdeqlssfleraakfladaids.GGrvlvhcvqGksrsssvtva

FLMICENMTLVEAIQTVQAHRNI-CPNSGFLRQLQVL
||.  .  || || . ..  | |  || |||.||   
fLikskgwtlkeayeylkerrsivapnrGflkqlakf

subfamily_MKPLV_pd Subfamily MKPLV 271-406 9.9e-21 67.9 In-house 28-156 (164) alignment
Range on Protein: 271-406
Range on HMM: 28-156/164.0
SLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQvdtgaKFyrGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVSRSATLVLA
 |.||.|  |...  | .| |||.|| . .| .     .|   .|.||  .. .|..   || ..  .| ..  |.    ||||||| .|.|||..  .|
tlylGnakhatnekvlkdlkithivnvsqekkd.....af..pksveYlqvkvedesdeqlssfleraakfladaids.GGrvlvhcvqGksrsssvtva

FLMICENMTLVEAIQTVQAHRNI-CPNSGFLRQLQVL
||.  .  || || . ..  | |  || |||.||   
fLikskgwtlkeayeylkerrsivapnrGflkqlakf

0045450 (Phosphotyrosine protein) phosphatases II 279-406 1.3e-20 69.8 In-house 104-299 (307) alignment
Range on Protein: 279-406
Range on HMM: 104-299/307.0
AARDK----------------SKLIQLGITHVVNAA----------------------AGKFQVDTGAKFYrGMSLEYYGIEADDN--------------
   .|                  | ..|.|..|.                         |.|.| .  . .   .. .. .|  |.              
dlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhy

---PFFDLSVYFLPVARYIRAALSV-----PQGRVLVHCAMGVSRSATLVLAFLMICEN--------MTLVEAIQTVQAHR-NICPNSGFLRQLQVL
   | .... .| .. . |......     ..|.||||| .||.|..|...|.||..          ..| ||.......| ....| ...|.|. .
tgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyea

0037934 (Phosphotyrosine protein) phosphatases II 267-404 1.8e-20 69.0 In-house 41-235 (243) alignment
Range on Protein: 267-404
Range on HMM: 41-235/243.0
EVWPSLFLGDA--------YAARDKSKLIQLGITHVVNAAAGK----------------------------------------FQVDTGAKFYRGMSLEY
.|.| |.....        ..| .   | .||||..|.    .                                          .|..  .. .. . |
yvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhy

YGIEADDNPF-FDLSVYFLPVARYIRAA-----LSVPQGRVLVHCAMGVSRSATLVLAFLMICE-NMTLVEAIQTVQAHRN--ICPNSGFLRQLQ
...   . |  ..  . ||  .| .  .        ..|.||||| .||.|..||..|.||.   ...| ||.......|.  .... ...|.|.
lpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrfly

subfamily_STYX_pd Subfamily STYX 264-407 6.2e-19 61.7 In-house 11-154 (166) alignment
Range on Protein: 264-407
Range on HMM: 11-154/166.0
HIDEVWPSLFLGdAYAARDKSKLIQL---GITHVVNAAAGKFQVDtgAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMG
...|. | ||||  |.|  |||| .|   ||||.|             |     .. |  ..  ||.  ..  |.  |  .|  .|.   |.||||   |
emqeilpglflg.pysaamksklevlkkhgithivcirqnieanl..ikpnfpdrfrylvldvadntveniirylptvkefiddslqk.ggkvlvhgnag

VSRSATLVLAFLMICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVLD
.||||.||.|..|    .   || . || .|  | ||.|| .||.. .
isrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeye

0042113 (Phosphotyrosine protein) phosphatases II 266-404 6.4e-19 63.8 In-house 48-236 (245) alignment
Range on Protein: 266-404
Range on HMM: 48-236/245.0
DEVWPSLFLGDAYAARDKS----KLIQLGITHVVNAAAGK---------------------------------------FQVD--TGAKFYRGMSLEYYG
....| ...... .. .       | .||||..|.                                            ..|      .   .. . |..
yritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylp

IEadDNPFFDLSVYFLPVARYIRAALS-VPQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHR-NICPNSGFLRQLQ
..  |..  ||. ..| . ...| ||.  ..|.||||| .||.|..|...|.||        ...| ||.. .. .| ..... ...|.|.
wp..dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrfly

0036941 (Phosphotyrosine protein) phosphatases II 264-406 1.4e-18 62.7 In-house 18-272 (297) alignment
Range on Protein: 264-406
Range on HMM: 18-272/297.0
HIDEVWPSLFLGDAYAARDKSKLI----------------------------------------------------------QLGITHVVNAAAGK----
. .|..| |.||. ..|. .  |                                                           ....|..|.         
efeellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgr

------FQVD-TGAKFYRGMSLEYYGIEA-----------------------------DDNPFFDLSVYFLPVARYIRAALSV-----PQGRVLVHCAMG
      .  .  . . | ...... ..|                               . | ...  .. .. ..|.....|     ..|.||||| .|
ekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaG

VSRSATLVLAFLM--------ICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVL
|.||.|...|.||        . ......||....  .| ..... ...|.|  .
vgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyea

0040438 (Phosphotyrosine protein) phosphatases II 286-406 1.4e-17 59.5 In-house 106-271 (317) alignment
Range on Protein: 286-406
Range on HMM: 106-271/317.0
LIQLGITHVVNA---------------------AAGKFQVDTGAKFYrGMSLEYYGIEADDN----------------PFFDLSVYFLPVARYIRAALSV
. ..|.|..|.                        |.|.| .   ..   . ... .|  |.                | ...  .. .. . ..|. ..
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrea

---PQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHRN-ICPNSGFLRQLQVL
   |.| ||||| .||.|..|...|.||       ..... ||.......|. .... ...|.|  .
ledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda

0038934 (Phosphotyrosine protein) phosphatases II 308-406 9e-17 56.8 In-house 72-172 (194) alignment
Range on Protein: 308-406
Range on HMM: 72-172/194.0
AKFYRGMSLEYYGIEADD---NPFFDLSVYFLPVARYIRAAlsVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQL
.. . .. .||. .   |    | ...   || ..  . ..   |.| |.||| .|..|..||| |.|. . .|.. |||....  | .. || ..|..|
peefekagieylklpfpddgtvPsleillrfldlvdeflne..dpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleal

QVL
.. 
lkr

0039614 (Phosphotyrosine protein) phosphatases II 286-405 1.3e-16 56.3 In-house 121-283 (297) alignment
Range on Protein: 286-405
Range on HMM: 121-283/297.0
LIQLGITHVVNAAAGK---------FQVDTGakFYRGMSLEYYGI------------------------------EadDNPFFDLSVYFLPVARYIRAAL
. ..|.|..|.    .         .  ..|   | ... .. ..                                 |.   ... ..| . ...| ||
vweqgvtvivmLtklvelgrkcaqywpeegg..tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwp..dhgvppslellleflelvreal

SV--PQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHR-NICPNSGFLRQLQV
.   ..|.||||| .||.|..|...|.||        .... ||..... .| ..... ...|.|. 
aelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflyd

0051429 (Phosphotyrosine protein) phosphatases II 270-404 7.7e-16 54.0 In-house 21-218 (272) alignment
Range on Protein: 270-404
Range on HMM: 21-218/272.0
PS-LFLGDAY---AARDKSKLIQLGITHVVNAAAGKFQVDTG-AKFYRGMSLEYYGIEADDNPFFdlSVYF-----------------------------
|  |.....     |.|  .| .|||...|.      .   .  ..  |. . .. |. |. |.   ....                             
pgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsapti..lygalrvtllseellldyilrellltlllsage

-------------------LPVARYIRAALSvpQGRVLVHCAMGVSRSATLVLAFLMIcENMT--------------LVEAIQTVQAHR-NICPNSGFLR
                    .. . ... |.  .|.|||||. |..|..|.|...|.. ....              | ||.. ..|.| .. .. ....
arevmhlhytdwpdhgvpqeallellellld..ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqyl

QLQ
.|.
fly

subfamily_DSP8_pd Subfamily DSP8 264-410 7.6e-15 48.8 In-house 14-154 (159) alignment
Range on Protein: 264-410
Range on HMM: 14-154/159.0
HIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTgakfYRGMSleYYGIEADDNPFFDLSVYFLPVARYIRAALSVpQGRVLVHCAMGVSR
 . .. . |.||    . ... | .|||..|.||     ....     .     .  .   |.   .|. .|     .|  | |  .||||||.  | ||
gptrilknlylGsqkdvlseellsklgisyvlnasnscpklee....lkesk..flrvPvkDkydekllpwfdksvefidkakse.ngrvlvhvlaGisr

SATLVLAFLMICENMTLVEAIQTVQAHR-NICPNSGFLRQLQVLDNRL
|||...|..|   .|.| || . |. .|  | ||  || ||   ...|
satvaiayimktlemsldeayrfvkekrptispnlnflgqLleyekel

subfamily_STYXL1_pd Subfamily STYXL1 267-408 5.8e-14 45.6 In-house 13-151 (157) alignment
Range on Protein: 267-408
Range on HMM: 13-151/157.0
EVWPS-LFLGDAYAARDKSKLIQLGITHVVNAAAGKFQvdtgakFYRGMSL--EYYGIEADDNPFFDLSVYFLPVARYIRAALSvPQGRVLVHCAMGVSR
|| |. |.||.   | ...    | .  .|| .    .      .. |..   .   |. .|..  ||   .  . ..|       .  |||    |.||
evlPgklylGnykqaqnpaikkdlkvkahvnvsmdadk......liagvadvakllhiavedeneadllerlkeavqfiekhkk.egevvlvfsnkGisr

SATLVLAFLMICENMTLVEAIQTVQA-HRNICPNSGFLRQLQVLDN
||....|.||  ...|| .| . ..  . |..|| .|. ||.  ..
saaviiaylmyskkitlkkaykylkkCkenvkPnrafveqlseWek

0043336 (Phosphotyrosine protein) phosphatases II 309-403 1.1e-13 46.7 In-house 171-269 (278) alignment
Range on Protein: 309-403
Range on HMM: 171-269/278.0
KFYRGMSLEYYGIEADDNPFfdLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHR-NICPNSGFLRQ
. . .. . |.|.  .. |       .|   ...| ||. ..| |||||  ||.|..|.....|.        ...| ||..... .| .....  ..|.
esrtvthyhylgwpdhgvpe..slsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrf

L
|
l

subfamily_MSG5_pd Subfamily MSG5 337-410 2.8e-11 36.8 In-house 87-160 (165) alignment
Range on Protein: 337-410
Range on HMM: 87-160/165.0
PVARYIRAALSVpQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAH-RNICPNSGFLRQLQVLDNRL
 ..| | || |  . ..||||  |.||||.|..|..|   |..| .| . ...   .| |. |.. ||   .  |
rltriihaatsk.rkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmeweval

0051299 (Phosphotyrosine protein) phosphatases II 325-394 3.5e-11 38.5 In-house 194-268 (288) alignment
Range on Protein: 325-394
Range on HMM: 194-268/288.0
DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHRNIC
|. . |    .|   |..| ||. ..| |.|||  ||.|..|.....|.       . ... ||....  .|. .
dhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgm

subfamily_PTPMT1_pd Subfamily PTPMT1 249-394 6.6e-11 37.0 In-house 4-151 (171) alignment
Range on Protein: 249-394
Range on HMM: 4-151/171.0
SLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLI-QLGITHVVNAaAGKFQVDT---GAKFYRGMSLEYYGIEADDNP-FFDLSvYFLPVARYIR
.| . . |..|.. |..| .   ..||      ....|| .  .  ||.     ... .     . .. . .|.. ..  |     ||    .   ..|.
tllynvlvekaskrnwydriDdtvilGalPfrslikeLiekenvkavvsl.neeyelkalansteewkklgveqlqlatvDfteapdle.klekgvefie

AALSVpQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNIC
   |  . || |||  | .|||||| ..||  |.... ||...... |.| 
kvask.gkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkii

0047943 (Phosphotyrosine protein) phosphatases II 327-394 1.3e-10 36.7 In-house 180-254 (273) alignment
Range on Protein: 327-394
Range on HMM: 180-254/273.0
PFFDLSVYFLPVARYIRAALSV--PQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHRNIC
   .   ..|   ...| ||.    .| |.|||  ||.|..|.....|.        .... ||.. .. .|  .
gvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgm

0046845 (Phosphotyrosine protein) phosphatases II 333-394 3.5e-10 35.2 In-house 185-256 (284) alignment
Range on Protein: 333-394
Range on HMM: 185-256/284.0
VYFLPVARYIRAALS--VPQGRVLVHCAMGVSRSATLVLAFLMICE--------NMTLVEAIQTVQAHRNIC
  .|   |..| .|.   ..| ..|||  ||.|..|.... |...         .... ||.. .  .|. .
edlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgm

0050432 (Phosphotyrosine protein) phosphatases II 333-394 2.6e-09 32.3 In-house 217-281 (308) alignment
Range on Protein: 333-394
Range on HMM: 217-281/308.0
VYFLPVARYIRAALsvPQGRVLVHCAMGVSRSATLVLAFLM-----ICENMTLVEAIQTVQAHRNIC
  .|   ...|  |  |.| ..|||  ||.|..|.... |.        .... ||....  .|. .
eilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgm

0048567 (Phosphotyrosine protein) phosphatases II 309-397 6.7e-09 30.3 In-house 32-121 (157) alignment
Range on Protein: 309-397
Range on HMM: 32-121/157.0
KFYRGMSLEYYGIEADDNPF-FDLSVYFLPVARYIRAALSVPQGRVLVHCAMGV---SRSATLVLAFLMICENMTLVEAIQTVqahRNICPNS
 |     | |.   .|. |.  .. . |  ..  .   |.   ... ||| .|    .|.|||. ..|... ..|  |||. .   | . |.|
yFsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiapl...rivrpgs

PTPc_DSPc_SM00012 340-388 1.4e-06 23.8 In-house 24-80 (105) alignment
Range on Protein: 340-388
Range on HMM: 24-80/105.0
RYIRAALSVPQ-----GRVLVHCAMGVSRSATLVLAFLMICENMTL---VEAIQTVQ
...||  .. .     . |.|||  ||.|..|.|.. .... ...    |.  |.|.
ellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivk

subfamily_PTPDC1_pd Subfamily PTPDC1 345-392 1.8e-06 22.5 In-house 109-156 (182) alignment
Range on Protein: 345-392
Range on HMM: 109-156/182.0
ALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRN
| .. .|.| |||  |  |   |. ..|.  ...|  .||..|...| 
afalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrp

subfamily_Laforin_pd Subfamily Laforin 305-391 2e-06 20.8 In-house 66-151 (183) alignment
Range on Protein: 305-391
Range on HMM: 66-151/183.0
DTGAKFYRGMSLEYYGIEADDNPfFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHR
.|  |.|.   | |  .  .|    .  |  || | |.  ||     .| |||  || ||...|  ||.   . .|      . |.|
itlkklykeeglayiwlptedls.tesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakr

subfamily_CDC14_pd Subfamily CDC14 308-391 3.4e-06 21.1 In-house 221-304 (328) alignment
Range on Protein: 308-391
Range on HMM: 221-304/328.0
AKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHR
.| |   . .  |..  |  | | |.    . .   ...   .| . |||  |. |  ||. ..||   ..|  |||  ..  |
kklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricr

Y_phosphatase Protein-tyrosine phosphatase 339-392 5.3e-06 21.4 Pfam-A 159-214 (235) alignment
Range on Protein: 339-392
Range on HMM: 159-214/235.0
ARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMT--LVEAIQTVQAHRN
 | ..   .  .| |.|||  ||.|..|.|.. .....  .   |.  |.|.  |.
irkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRk

Y_phosphatase Protein-tyrosine phosphatase 339-392 5.3e-06 21.4 In-house 159-214 (235) alignment
Range on Protein: 339-392
Range on HMM: 159-214/235.0
ARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMT--LVEAIQTVQAHRN
 | ..   .  .| |.|||  ||.|..|.|.. .....  .   |.  |.|.  |.
irkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRk