Gene SSH3 in Homo sapiens

Synonym: SSH3L, SSH3

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily Slingshot
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP043_AA protein Get Run
HsapP043_AA_335-480 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Slingshot_pd Subfamily Slingshot 320-483 2.3e-85 278.2 In-house 1-164 (169) alignment 
Range on Protein: 320-483
Range on HMM: 1-164/169.0
YRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVL
|..||||.||....|.|.||.|| |.||||||||.|||||..|.|..|||...|||||.||.|.|.|.|..|||...||..|.||..|||.|...|..||
ykefidnemlvilgqldsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvl

VHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSH
|||||||||||.||.|||||.|..|||.||..|.| | ...||.|||.||..|.|||.||.|.|
vhckmGvsrsastviayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGileaskqrh
subfamily_DSP1_pd Subfamily DSP1 338-478 6.6e-46 150.4 In-house 18-158 (163) alignment 
Range on Protein: 338-478
Range on HMM: 18-158/163.0
ASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYA
  .| ..|||||| .|.||| |.....|.|||...|.||.... |.|... | |...|..  ...|   ||....... .||.||..|.|||.. .||| 
vekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclayl

MKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTA
||. ..|||.|   |.. |.| .|| || .||  |.  |..
mktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekklll
subfamily_DSP19_pd Subfamily DSP19 338-474 4.8e-45 147.6 In-house 12-148 (152) alignment 
Range on Protein: 338-474
Range on HMM: 12-148/152.0
ASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYA
.. . |.|||||   ||. |.|.....|||||.| ...|..|. ||| .. ..|.. ..|| ..||.. ||| || .   |||||. ||||||. |.|| 
vgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviayl

MKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQG
||. | |||.||. |.| || ..|| ||..||. |. 
mkkeelsleealelvrearpcikPneGFikqLkeyea
0044763 (Phosphotyrosine protein) phosphatases II 316-477 5.7e-42 138.7 In-house 1-171 (178) alignment 
Range on Protein: 316-477
Range on HMM: 1-171/178.0
PLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPER---------FTYHNVRLWDEESAQLLPHWKETHR
||  .| ...| . |. ..   ||.|.|.||||| ..|..|| |... .|||.|.. |. .....          ..|... . |    .|| |. |...
pldrtrvllsnleglersdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefve

FIEAAR-AQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPiARPNPGFLRQLQIYQGILT
|||.|.  .|  |||||..||.||.. |.|| ||.. .|||.|...|.| || . ||||.||||. .. .| 
fieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrll
subfamily_DSP14_pd Subfamily DSP14 337-480 7.6e-39 127.2 In-house 6-148 (157) alignment 
Range on Protein: 337-480
Range on HMM: 6-148/157.0
RASRIFPHLYLGsEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAY
  |.| |.|.|.    | . |.|.....|.|.|...|. |   . . . .|.. |...|.| .|. |.   ||.....| ..||||..||||||. .|||
alsqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclay

AMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASR
 ||  . ||..| ..|.. ||| ||| || .||. |   |... 
lmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgks
0048076 (Phosphotyrosine protein) phosphatases II 338-475 3.2e-38 126.0 In-house 4-141 (145) alignment 
Range on Protein: 338-475
Range on HMM: 4-141/145.0
ASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYA
.|.|.|.||||| ..| .||.|... .|..||...|....... ..|... ..| .  .|| .. |  .|||.|...|  |||||..||.|... |.|| 
pseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl

MKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGI
|... .|||.||..|.. ||.| ||||.||.|. .. .
mlllgvsleealelvrsqrpgavpnpgqlrflyefele
subfamily_DSP12_pd Subfamily DSP12 339-477 4.8e-38 125.0 In-house 3-144 (155) alignment 
Range on Protein: 339-477
Range on HMM: 3-144/155.0
SRIFPHLYLGSEWNAANLEELQRNRVTHILNMARE-IDNFYPER--FTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLA
||| | ||||.  .... | |.   .||.| ...| .... ...   .. .. . ||... .| |  |. .||| |.... .|||||..|||||...|.|
srilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviA

YAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILT
| ||....|||.||. |.| .| ..|| |||.||.... . .
YlmkkeklslekAlklvkekkpeiepNegFleQLklfekmgc
PTPc_motif_SM00404 338-473 1.3e-37 123.7 In-house 2-138 (140) alignment 
Range on Protein: 338-473
Range on HMM: 2-138/140.0
ASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFY-PERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAY
 ||| |||||||. .| |.. |. ...||..|...|... .  ..|.. .. | |.|...|....... .|||.|...|. |||||..||||||. ..||
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

AMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQ
 |.....||..|.. |.| ||| .|| .|.|||. |.
lmryrqlslaeayefvkerRpiispnlnfvrqLieye
subfamily_DSP10_pd Subfamily DSP10 337-479 2e-37 122.5 In-house 13-156 (159) alignment 
Range on Protein: 337-479
Range on HMM: 13-156/159.0
RASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPE-RFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLA
 ||...|.|.|||| .||.|. |.| ..|..||.. .. |.. |  ..|. . . | .. .|  ...|   ||| || .|..|||||. |.||||. |.|
pasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTAS
| ||. . ||..| ..|.| |||  || .|. ||  .   |. |
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks
0048179 (Phosphotyrosine protein) phosphatases II 339-475 2.3e-37 123.2 In-house 5-143 (144) alignment 
Range on Protein: 339-475
Range on HMM: 5-143/144.0
SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERF--TYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAY
|.|.|.||||| . | .||.|... .|...|.. | .. ..||.  .|... . | .  .|| .. |. .|||.|...|  |||||..||.|... |.||
seilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaay

AMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGI
 || . .|||.||..|.. ||.| ||||.||.|. |. .
lmkklglsleealalvrsrrpgavpnpgqlrfLleyekl
0049772 (Phosphotyrosine protein) phosphatases II 339-488 4.2e-34 114.1 In-house 148-285 (314) alignment 
Range on Protein: 339-488
Range on HMM: 148-285/314.0
SRIFPHLYlgSEWNAANLEELQrnrvthilnmaREI--DNFYPER-FTYHNVRLWDeESAQLLPHWKETHRFIEAArAQGTHVLVHCKMGVSRSA-ATVL
 .|.. ..  .|..||.||.|.           .|.  ....... ..|... ..| .|| || ...|  .|||.|  .|. ||||||.|..|.. . |.
llildgng..neptaadlellk...........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvva

AYAMKQYECSLEQALRHVQELRPiARPNPGFLRQLQIYQGILTASRQSHVWEQK
|| ||.. .|||.||..|.. || ..|||||..||. |. || |...   . .|
aylmkllgvsleealedvrlkRp.inpnpgfieqleqyefilealleylkflkk
subfamily_DSP15_pd Subfamily DSP15 339-478 6e-34 111.3 In-house 3-141 (151) alignment 
Range on Protein: 339-478
Range on HMM: 3-141/151.0
SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPErFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAM
|.. | ||||   .. . | |.....||||..  .  .. .. ..|. ... |  ||.|  . ||. .|| ..| ..  ||||| .|||||.  | || |
skvlpglylgnfrdskdeelLkeknithilsvhdnakkllkd.ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlm

KQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTA
   | . ..||. ... | .| || || |||. |.   ..
tvtelnwrdalevikaaRsvanPnfGfkrqlkeyektklk
subfamily_DSP6_pd Subfamily DSP6 335-477 1.4e-33 109.7 In-house 11-155 (158) alignment 
Range on Protein: 335-477
Range on HMM: 11-155/158.0
RDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPE--RFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAAT
.    .| |.|||||. .|.||| |.. .. ..||.. ...|.. |   ..| .. . |. |..|  .. |. .||. || . ..|||||  |.||| . 
aefpveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtv

VLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILT
.||| ||....||..|   |.. ..   ||  |. ||  ..  |.
tlaylmkklalslndaydlvkkrksnisPnfnfmgqlldferslr
0041856 (Phosphotyrosine protein) phosphatases II 337-476 5.1e-33 109.6 In-house 18-172 (182) alignment 
Range on Protein: 337-476
Range on HMM: 18-172/182.0
RASRIFPHLYLGSEWN--------------AANLEELQRNRVTHILNMAREI---DNFYPERFTYHNVRLWDEESAQllphWKETHRFIEAARAQGTHVL
  ..| ..||||| ..              |..|. |.....|.|.|.. |    .... . ..|...   | .       . |...|||.....|  ||
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvl

VHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP--IARPNPGFLRQLQIYQGIL
|||..||.|... |.|| ||....|||.|...|.. ||  . .|| .|..||.... .|
VHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallelll
subfamily_LRR-DSP_pd Subfamily LRR-DSP 299-475 7e-33 107.8 In-house 87-257 (263) alignment 
Range on Protein: 299-475
Range on HMM: 87-257/263.0
SVTSKEIRQALELrLGLPLQqYRDFidNQMLLLVAQrdRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNV-RLWDEESAQL
 .   .||.  || . ||.. |..   .....||.     . | ..|.||.   | |   |. . |||||    ... ..|. | |  .  . | . |..
clkelnirdnrel.islpve.ykqv..eslitlvss..vPdeiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadi

LPHWKETHRFIEAARAQGThVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGI
  |..||  |||  | .|  |||||. |||||.. |..| ||. .  ...||  |.. ||  .|||||. ||. |.  
sqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekk
0043147 (Phosphotyrosine protein) phosphatases II 339-476 2.3e-32 107.5 In-house 20-160 (172) alignment 
Range on Protein: 339-476
Range on HMM: 20-160/172.0
SRIFPHLYLGSEWNAANLEELQRNRVTHILNMARE---IDNFYPERFTYHNVRLWDEESAqLLPHWKETHRFIEA--ARAQGTHVLVHCKMGVSRSAATV
 |..........  | ... |... .|||.|. ..    ...... ..|. .   |     || .. |. .||.   |. .|  |||||..||.|... |
drfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlv

LAYAMKqYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGIL
.|| |. . .|||.|...|.| ||.| .||...|.|. .. .|
aaylml.lglsleeavalvrekRpgavqnpsqyrflyyfekll
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 344-470 7.8e-32 103.8 In-house 14-141 (148) alignment 
Range on Protein: 344-470
Range on HMM: 14-141/148.0
HLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFT-YHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYE
.|.|||   ||.|| |.   ||.| |...| || . .|   | .|.| |..  .|   ...   |.. |...|  ||||..||||||.| .|.. ..  .
fLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkr

CSLEQALRHVQELRPIARPNPGFLRQLQ
 ||..||  |.. |.  .||.|||.||.
vslkealalvkskrryvdpnlgfLkqLa
DSPc Dual specificity phosphatase, catalytic domain 345-473 8.7e-32 104.8 Pfam-A 1-131 (133) alignment 
Range on Protein: 345-473
Range on HMM: 1-131/133.0
LYLGSEWNAAnLEELQRNRVTHILNMAREIDN---FYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQY
|||||. .|  |. |. . .|...|...|..|   . .....| .. . ||..... .. .|. .|||.|...|  |||||..|.||||. ..|| ||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

ECSLEQALRHVQELRPIARPNPGFLRQLQIYQ
..||..|...|.| |.. .|| ||||||  |.
nlslneAyefvkerrskispnagflrqLleye
DSPc Dual specificity phosphatase, catalytic domain 345-473 8.7e-32 104.8 In-house 1-131 (133) alignment 
Range on Protein: 345-473
Range on HMM: 1-131/133.0
LYLGSEWNAAnLEELQRNRVTHILNMAREIDN---FYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQY
|||||. .|  |. |. . .|...|...|..|   . .....| .. . ||..... .. .|. .|||.|...|  |||||..|.||||. ..|| ||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

ECSLEQALRHVQELRPIARPNPGFLRQLQIYQ
..||..|...|.| |.. .|| ||||||  |.
nlslneAyefvkerrskispnagflrqLleye
subfamily_DSP3_pd Subfamily DSP3 337-476 7.7e-31 100.9 In-house 10-157 (162) alignment 
Range on Protein: 337-476
Range on HMM: 10-157/162.0
RASRIFPHLYLGSEWNAANLEELQRNRVTHILNMARE----I---DNFYP-ERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQ-GTHVLVHCKMGVS
..  ..|.||.| |  | . ..|..  .||.|| |.     .   ..||    ..|. . . |  ...|  ..... .||..| .|  ..|||||..|||
evdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvs

RSAATVLAYAMKQYECSLEQALRHVQELRPIaRPNPGFLRQLQIYQGIL
|||. |||| | . . .| .|.|.|.. | | .|| |||.||. ..  |
RsatlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeel
0046846 (Phosphotyrosine protein) phosphatases II 338-473 9.3e-30 99.1 In-house 12-169 (176) alignment 
Range on Protein: 338-473
Range on HMM: 12-169/176.0
ASRIFPHLYLGSEW----------NAANLEELQRNRVTHILNMAREI-----------DNFYPERFTYHNVRLWDEESAQLlPHWKETHRFIEAARAQGT
 ..| ..|.||| .           |..||.|.....|...|.  |.           . .. . ..|...   |    .|  .. |  .||. |. .| 
ldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkegg

HVLVHCKMGVSRSAATVLAYAMKQ-YECSLEQALRHVQELRP-IARPNPGFLRQLQIYQ
 |||||..|..|... |.|| ..  .  |.|.||..|.| ||  | ..|...|.|. . 
pvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefe
0049260 (Phosphotyrosine protein) phosphatases II 339-475 3.7e-29 96.8 In-house 9-148 (152) alignment 
Range on Protein: 339-475
Range on HMM: 9-148/152.0
SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNF---YPERFTYHNVRLWDEESAQLLPHWKETHRFIEA-ARAQGTHVLVHCKMGVSRSAATVL
 .. .....|... | ... |... .|.|... .. ..     .. ..|...   |    .|  . .. ..|||  |. .|  |||||. ||.|... |.
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlva

AYAMKqYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGI
|| |. . .|||.|...|.| ||.| ||||.||.|. ....
aylml.lgvsleeavalvrekRpgavpnpgqlrflyefekl
0045098 (Phosphotyrosine protein) phosphatases II 338-473 6.5e-28 93.3 In-house 22-268 (278) alignment 
Range on Protein: 338-473
Range on HMM: 22-268/278.0
ASRIFPHLYLGSEW-----------------------------------------NAANLEELQRNRVTHILNMAREIDN--------------------
 |.|.|.||||. .                                          |.... |. ...|.|.........                    
pseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdf

-----------------------------FYPERFTYHNVRLWDEESAQLLP---HWKETHRFIEAARA--------------QGTHVLVHCKMGVSRSA
                             ...  .|...   |.. ..  ||   .. |  .||..|..              .|. |||||..||.|..
tvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtG

ATVLAYAMKQY---ECSLEQALRHVQELRPI-ARPNPGFLRQLQIYQ
. |.|| |...    ..|..|...... ||. | .|....|.|  ..
tlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefl
subfamily_DSP8_pd Subfamily DSP8 333-476 8e-28 91.0 In-house 11-154 (159) alignment 
Range on Protein: 333-476
Range on HMM: 11-154/159.0
AQrDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMARE-IDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAA
|. ..  || ..|||||. .. . | |... ....||. .. ..    .   .. | . |. . .||| ....  ||. |... ..||||.  | ||||.
ad.vgptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsat

TVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGIL
 ..|| ||. | ||..| |.|.| ||   ||  || ||  |.  |
vaiayimktlemsldeayrfvkekrptispnlnflgqLleyekel
subfamily_MKPLT_pd Subfamily MKPLT 344-475 9.8e-28 90.7 In-house 28-159 (164) alignment 
Range on Protein: 344-475
Range on HMM: 28-159/164.0
HLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYEC
.||||   .| | . |.   .|||.|...|  . .|. . | .|.. ||   || .. . .  |.  |   |  ||||| .|.|||... .|. .|    
tlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgw

SLEQALRHVQELRPIARPNPGFLRQLQIYQGI
 |..|  ...| | |..|| |||.||  .. .
tlkeayeylkerrsivapnrGflkqlakfeel
subfamily_MKPLV_pd Subfamily MKPLV 344-475 9.8e-28 90.7 In-house 28-159 (164) alignment 
Range on Protein: 344-475
Range on HMM: 28-159/164.0
HLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYEC
.||||   .| | . |.   .|||.|...|  . .|. . | .|.. ||   || .. . .  |.  |   |  ||||| .|.|||... .|. .|    
tlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgw

SLEQALRHVQELRPIARPNPGFLRQLQIYQGI
 |..|  ...| | |..|| |||.||  .. .
tlkeayeylkerrsivapnrGflkqlakfeel
0037934 (Phosphotyrosine protein) phosphatases II 339-472 1e-27 92.7 In-house 40-237 (243) alignment 
Range on Protein: 339-472
Range on HMM: 40-237/243.0
SRIFPHLYLGSE--------WNAANLEELQRNRVTHILNMAREI---------------------------------------------DNFYPERFTYH
....|.|....         . |.... |.....|.|... ...                                             |... . . ||
iyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyh

NVRLWD----EESAQLLPHWKETHRFIEA-----ARAQGTHVLVHCKMGVSRSAATVLAYAMKQY-ECSLEQALRHVQELRPI-ARPNPGFLRQLQIY
 .   |    .. ..|| ...|.. |||.     |. .|  |||||..||.|... ..|| |... ...||.|.....| ||  | ..|...|.|. .
ylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyea
0036282 (Phosphotyrosine protein) phosphatases II 339-474 8.4e-27 89.4 In-house 13-167 (174) alignment 
Range on Protein: 339-474
Range on HMM: 13-167/174.0
SRIFPHLYLGSEWNAaNLEELQRNRVTHILNMAREI---------------DNFYPERFTYHNVRLWDEESAQLLPhWKETHRFIEAARAQ--GTHVLVH
|.| |.|..|.   | ..|.|.....|..... .|.               . .... ..|. .   | .   |   . |  .|.| |...  |  ||||
syitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVH

CKMGVSRSAATVLAYAMKQYEC-SLEQALRHVQELR---PIARPNPGFLRQLQIYQG
|..||.|... |.|| |... . ||..||..|.|||   | . ..|...|.|. .. 
CsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfek
PTEN_1 340-479 6.3e-26 86.4 In-house 43-194 (196) alignment 
Range on Protein: 340-479
Range on HMM: 43-194/196.0
RIFPHLYLGSEWNA-ANLEELQRNRVTHILNMAREIDN---------FYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARA--QGTHVLVHCKMGVS
.|...||.||.  . |.|..|. . .|...|.. | ..         |. ....|...   |     |  ....  .|||....  .|  |||||| |..
eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlg

RSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTAS
||.  | || |. .  . ..||..|.| || ..||......|. |.  | |.
RsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae
0040439 (Phosphotyrosine protein) phosphatases II 344-472 2.2e-25 85.2 In-house 35-241 (249) alignment 
Range on Protein: 344-472
Range on HMM: 35-241/249.0
HLYLGSEWN------------------------AANLEELQRNRVTHILNMAREIDN-------------------------------------------
 |.|..  |                        ..... |.....|.|... ..  .                                           
glflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnl

FYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARA------QGTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGF
 ..| .|.. ..  |    .. |. ... .||||.|       .|. |||||..||.|... ..|| |     | .. .||.|...... || | .||..
ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeq

LRQLQIY
.|.|. .
yrflyea
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 337-473 2.8e-25 82.5 In-house 2-149 (154) alignment 
Range on Protein: 337-473
Range on HMM: 2-149/154.0
RASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPER---------FTYHNVRLWDEESAQLLPHWKETHRFIEAAR--AQGTHVLVHCKMG
| |.   .||..|   | |  .|| .....|||..  |.| ....         . | |..|.|.   ... . . .  ||. |    .  .||||.. |
rnskeaiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkG

VSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQ
|||||| ...| |.. . || .||  ... |.| .|| |||.||.|..
vsrsaallisylmdklkislslalellkdsryiikPnqGflkqleife
0045450 (Phosphotyrosine protein) phosphatases II 357-472 6e-25 84.0 In-house 125-299 (307) alignment 
Range on Protein: 357-472
Range on HMM: 125-299/307.0
EELQRNRVTHILNMAREIDN-------FYPER---------------------FTYHNVRLWDE-----------------ESAQLLPHWKETHRFIEAA
. |....||.|... .....       ..|.                      .|.......|                     .. |...|. .|||..
rmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev

RA------QGTHVLVHCKMGVSRSAATVLAYAMKQYE--------CSLEQALRHVQELRPIARPNPGFLRQLQIY
|.      .|. |||||..||.|... ..|| |...         ..|..|.....| || | .||...|.|. .
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyea
0051082 (Phosphotyrosine protein) phosphatases II 338-472 3.6e-24 80.5 In-house 8-149 (151) alignment 
Range on Protein: 338-472
Range on HMM: 8-149/151.0
ASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPE------RFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQ-GTHVLVHCKMGVSRSA
.|.. ..||...   |..||.|... ...|.|.  |  . |         ...... ..|    .|  ....  .|.|..... .  |||||..|..|..
fsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTG

ATVLAYAMKqYECSLEQALRHVQELRP-IARPNPGFLRQLQIY
. |..| |. . .|||.||..... || . .|| .|| ||. .
tlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal
subfamily_STYX_pd Subfamily STYX 334-481 5.9e-24 78.0 In-house 8-162 (166) alignment 
Range on Protein: 334-481
Range on HMM: 8-162/166.0
QRDRASRIFPHLYLGSEWNA--ANLEELQRNRVTHILNMAREID-----NFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGV
.|     |.| |.||    |  . || |... .|||. . ..|.       .|.|| |  . . |.   ... .  ... ||. .  .| .|||| . |.
krremqeilpglflgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagi

SRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQ
||||| |.|| |. |     .| ..||| |    || || .||. |. |  |  .
srsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylaklt
0042113 (Phosphotyrosine protein) phosphatases II 339-472 8.8e-24 79.7 In-house 43-238 (245) alignment 
Range on Protein: 339-472
Range on HMM: 43-238/245.0
S-----RIFPHLYLGSEWNAANLE----ELQRNRVTHILNMAREI----------------------------------------------DNFYPERFT
|     || |......   . ..|     |.....|.|... .|                                               |... | ..
syvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevih

YHNVRLWDEESAQLLPHWKETHRFIEAARA--QGTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGFLRQLQIY
|| .   |   . || .  . ..|.. |.|  ... |||||..||.|... ..|| |     | .. |||.|...... || |...|...|.|. .
yhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyea
0040438 (Phosphotyrosine protein) phosphatases II 357-472 1.5e-22 75.7 In-house 104-271 (317) alignment 
Range on Protein: 357-472
Range on HMM: 104-271/317.0
EELQRNRVTHILNMAREIDN---------------------------FYPERFTYHNVRLWDE----------------ESAQLLPHWKETHRFIEAARA
. .....||.|... .. ..                           .. . .|.......|                     . |....  .|.||.|.
rmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavre

Q----GTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGFLRQLQIY
.    |. |||||..||.|... ..|| |     | .....|.|.....| || | ..|...|.|  .
aledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda
subfamily_STYXL1_pd Subfamily STYXL1 341-472 5e-21 68.5 In-house 14-149 (157) alignment 
Range on Protein: 341-472
Range on HMM: 14-149/157.0
IFPH-LYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFT---YHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAY
. |. |||| . .| | .  .  .|   .|.. . |...          .... ||. |.||.. ||  .|||  . .|  |||  . |.||||| ..||
vlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiay

AMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIY
 | ... .|..|. .... ..  .|| .|. ||. .
lmyskkitlkkaykylkkCkenvkPnrafveqlseW
0036941 (Phosphotyrosine protein) phosphatases II 338-472 1.6e-20 69.1 In-house 19-272 (297) alignment 
Range on Protein: 338-472
Range on HMM: 19-272/297.0
ASRIFPHLYLGSEWNAANLEELQRNR----------------------------------------------------------VTHILNMAREIDNFY-
 ....|.|.||| . |...| |..||                                                          ||.|... .....   
feellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgre

------------------------------PERFTYHNVRLWD----------------EESAQLLPHWKETHRFIEAARA------QGTHVLVHCKMGV
                               . .|.......|                     . .....  .|||..|       .|. |||||..||
kcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGv

SRSAATVLAYAM--------KQYECSLEQALRHVQELRPIARPNPGFLRQLQIY
.||.. ..|. |        |...... .|.... | || | ......|.|  .
gRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyea
0051429 (Phosphotyrosine protein) phosphatases II 320-472 2.5e-20 68.7 In-house 6-220 (272) alignment 
Range on Protein: 320-472
Range on HMM: 6-220/272.0
YRDFIDNQMLllvaqrdrASRIFPH-LYLGSEW---NAANLEELQRNRVTHILNMAREI------DNFYPERFTYHNVRLWDEESAQLLPHW--------
|  . |  ..         ... |. ||... .   .||... |.......|... .|         .|.. ..|... ..|..  . | ..        
yiNardvggy........grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllse

----------------------------------------KETHRFIEAARAqGTHVLVHCKMGVSRSAATVLAYAMKqYECS--------------LEQ
                                        .. ....|. .. |  |||||. |..|..  |... .  .  |              ||.
ellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlylee

ALRHVQELRPIARPNPGFLRQLQIY
|...... || |.........|. .
aveelraqrpgavqteeqylflyea
0039614 (Phosphotyrosine protein) phosphatases II 357-472 9.7e-20 66.7 In-house 119-284 (297) alignment 
Range on Protein: 357-472
Range on HMM: 119-284/297.0
EELQRNRVTHILNMAREIDN-------------------------FYPERFT-----------------YHNVRLWDEESAQLLPHWKETHRFIEAARA-
. .....||.|... .....                         .. . .|                 .. .   |    ..| .  |  .... |.| 
rmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealae

--QGTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGFLRQLQIY
  .|. |||||..||.|... ..|| |     | .. ....|.....| || |...|...|.|. .
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflyda
0038934 (Phosphotyrosine protein) phosphatases II 342-475 1.9e-19 65.5 In-house 35-175 (194) alignment 
Range on Protein: 342-475
Range on HMM: 35-175/194.0
FPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQ--LLPHWKETHRFIEAA-----RAQGTHVLVHCKMGVSRSAATVL
.. ||  | ..  .. .|.  ........  .   . ||.|. ....  .         |  . ..||....     . .|  |.||||.|..|..  | 
ieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva

AYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGI
|| .. . .|.|.|.....| || | ||...|..|. . . 
aYLiyrlgmsaeeAialfrekRpgaipnqdyleallkryke
DEK_C DEK C terminal domain 281-329 6.1e-18 54.0 Pfam-A 2-50 (54) alignment 
Range on Protein: 281-329
Range on HMM: 2-50/54.0
EQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQML
...|..|....|  .|||.||.|..|..|| |||..|.....||.... 
deeikeevreiLkeaDLetvTkkqvrkeLearlgvdLserKafIkdlie
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 344-470 7.5e-18 58.0 In-house 5-135 (145) alignment 
Range on Protein: 344-470
Range on HMM: 5-135/145.0
HLYLGSEWNAANLEELQRNRVTHILNMARE----IDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMK
.|| ||  .| ..  ||   .. |.|||       .. . | ..   .   | || .|  |. |   ||.  . .|. |.|||  ||||| .  .|. ||
rlyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmk

QYECSLEQALRHVQELRPIARPNPGFLRQLQ
  . .| .| | |.  |  | ||  ||..| 
ycnmtlseaarqvrsnrllaypnvtflknll
0043336 (Phosphotyrosine protein) phosphatases II 359-471 1.4e-16 56.3 In-house 108-271 (278) alignment 
Range on Protein: 359-471
Range on HMM: 108-271/278.0
LQRNRVTHILNMAREIDN------------------------------------------FYPERFT---YHNVRLWDEESA-QLLPHWKETHRFIEAAR
.. ..||.|... .. ..                                           ..| .|   || .   | .   .| ....  ....|| .
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale

AQGTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGFLRQLQI
 ... |||||. ||.|... ...| .     | .. .||.|.....| || | ..| ..|.|  
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflye
subfamily_MSG5_pd Subfamily MSG5 343-478 3.7e-16 52.7 In-house 32-162 (165) alignment 
Range on Protein: 343-478
Range on HMM: 32-162/165.0
PHLYLGSEwnaANLEELQRNRVthILNMAREIDNFY--PERFTYHNVRlWDEESaQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQ
..||| ||    .|.||    .  ..|.|.||...        |. .. |. .| ..     .  | | ||.... ..||||. |.||||. ..|| || 
eklylyse...pklkellsfdl..vinvakeindlellvpavkyyhie.wehds.kivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimky

YECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTA
|. ||..|  ...       |. |.. ||  .. .|..
ynlslrdaydklksvaddispsiglifqlmewevalsk
subfamily_PTPMT1_pd Subfamily PTPMT1 380-474 4.5e-15 50.5 In-house 72-166 (171) alignment 
Range on Protein: 380-474
Range on HMM: 72-166/171.0
ERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQG
.  .. ... .|   |  | . ... .|||  . .|  | |||| | .|||. | .| ||....|.|.||..... |.| | .   ...|| |. 
lgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyee
0047943 (Phosphotyrosine protein) phosphatases II 364-469 8.2e-14 47.2 In-house 102-264 (273) alignment 
Range on Protein: 364-469
Range on HMM: 102-264/273.0
VTHILNMAREIDN----------------------------------------------FYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARA----
|..|  . .....                                               ..| .|.. .   .    .  |....  .|||..|     
vrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalea

--QGTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGFLRQL
  ... |.|||. ||.|... .... .     | .. ....|...... || . ..| ..|.|
lpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
0051299 (Phosphotyrosine protein) phosphatases II 364-467 9.8e-12 40.4 In-house 117-276 (288) alignment 
Range on Protein: 364-467
Range on HMM: 117-276/288.0
VTHILNMAREIDN-----------------------------------------------FYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQ--
|..|  . .....                                               .  | .|..     .    .  .....  .|....| .  
vrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala

--GTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGFLR
  |  |.|||. ||.|... .... .     |........|.... | || . ..|  .|
sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyr
0050432 (Phosphotyrosine protein) phosphatases II 393-465 1e-11 40.2 In-house 208-287 (308) alignment 
Range on Protein: 393-465
Range on HMM: 208-287/308.0
ESAQLLPHWKETHRFIEAARAQ--GTHVLVHCKMGVSRSAATVLAYAM-----KQYECSLEQALRHVQELRPIARPNPGF
.  .  |....  .|.|..| .  |  ..|||. ||.|... .... .     |........|.... | || . ..|  
pdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeq
0046845 (Phosphotyrosine protein) phosphatases II 394-464 1.9e-10 36.1 In-house 177-261 (284) alignment 
Range on Protein: 394-464
Range on HMM: 177-261/284.0
SAQLLPHWKETHRFIEAARAQ------GTHVLVHCKMGVSRSAATVLAYAMKQY--------ECSLEQALRHVQELRPIARPNPG
  .  |. .   .|....| .      |  ..|||. ||.|... .... ....        ......|.... | || .  .. 
dhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtle
0048567 (Phosphotyrosine protein) phosphatases II 401-457 1.9e-07 25.6 In-house 60-119 (157) alignment 
Range on Protein: 401-457
Range on HMM: 60-119/157.0
WKETHRFIEAARAQGTHVLVHCKMGV---SRSAATVLAYAMKQYECSLEQALRHVQELRP
..  ..|..  . .| .. ||||.|    .|.|  . .|... .  . |.|.....  ||
ilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrp
subfamily_CDC14_pd Subfamily CDC14 398-457 1.2e-06 22.6 In-house 246-305 (328) alignment 
Range on Protein: 398-457
Range on HMM: 246-305/328.0
LPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP
 |. .  ..|.|.|      . |||| |. |  . . .| ||.|. . ..|. ...  ||
tPsdaivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrP
subfamily_RNGTT_pd Subfamily RNGTT 399-457 5.3e-06 20.2 In-house 92-155 (189) alignment 
Range on Protein: 399-457
Range on HMM: 92-155/189.0
PHWKETHRFIEAA-----RAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP
|.  ....||.       .   . . |||. |  |.   . .| ... ..|.|.|..  .. ||
PeaeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRp