Gene MTMR7 in Homo sapiens

Synonym: MTMR7

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR6
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP058_AA protein Get Run
HsapP058_AA_125-511 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR6_pd Subfamily MTMR6 109-509 5.6e-222 729.1 In-house 1-397 (397) alignment 
Range on Protein: 109-509
Range on HMM: 1-397/397.0
LYCFSFNPMLDKEEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQP
||.||..|. ||||...|| |.||..||||||.||..|.|.|.|.||..||.||.|||||||||....||||||||..|.|||||..|.|.|.|||.|||
lyafsykpkkdkeekvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqp

LSGFSARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSG
||||||||||||..|.||||||| |...|||||||||||.||.|||||||||||||||||||.|||||||||.||||.|||.||||.|.|.||.|||.||
lsgfsarcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsglessg

WLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQ
||.||||..||.|||||||.||||||||||||||||||||||.|||||||.|||.|||.|||||.|.||||||..|.|.||.|.||.||...||.|||||
wlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvwq

LMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQtqGTLHLPTTPCNFmyKFWSGMYNRFE
|.||||.|||||||||.....|.||||||.||.|..|.||.||..|||.||||.|.....||||||..|....  ..|.. |.|...  |.|...||||.
lleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetek..evlkpdtapaal..klwralynrfd

K
|
k
0040695 (Phosphotyrosine protein) phosphatases II 124-507 6.2e-148 486.4 In-house 5-385 (388) alignment 
Range on Protein: 124-507
Range on HMM: 5-385/388.0
EQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFS-ARCLEDEQM
| ||.|.|  .|..|.||....|..|.||..| .|.|||  |.||||..  ... ...|||..|.|||||....|.|...||||||.|..  |.||||..
eegwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledekl

LQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCeLKSPSMSDFLWGLENSGWLRHIKAIMDAGIF
|.||.|..|.......||.||||||.||||.|.|.||||.|.|....|..|.||||.|.||||.|..| |..|.....|. ||.|||| .|| |... ..
leailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldac.lnvpdslnllslleesgwldliklilelavl

IAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDG--DPKEISPVIDQFIECVWQLMEQFPCAFEFN
|.| .. .. |||||||||||||.|..| | |||||.||||.||.|||||.|.|||||| .|.| |..  |.||.|||. .|..|||||. |||.|||||
ivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFn

ERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQtqgtlHLPTTPCNFMYKFWSGMYNRF
||.|... .|.|||.||.||.||.|||.||...|||.||| .|. .. ..||||.  ....      |   .... ...|...|.|.
erlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpssle.....vllpslsvldlllWleyylrw
Myotub-related Myotubularin-like phosphatase domain 108-449 1.9e-145 477.1 Pfam-A 1-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 108-449 1.9e-145 477.1 In-house 1-352 (353) alignment
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 110-507 7.1e-138 452.1 In-house 1-402 (404) alignment 
Range on Protein: 110-507
Range on HMM: 1-402/404.0
YCFSFNPMLDKEEreQGWVLIDLSEEYTRMGLPNH-YWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQP
..||...   . |  .||.. |  |||.|.|....  |..|..| ||..|..||  | ||.| . . .. ...|||. |.||||.  ......| |||||
fafsysekksvle..dgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqp

LSGFS-ARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENS
| | . .|. |||.....||||.. .. .|..|.|||.||.||.| |.|||. ..|.| . .| .||||| .|.||.|. ....    . ...|  ||.|
lvGltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlseless

GWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGN-LDGDPKEISPVIDQFIECV
.|| ||| .. .   |.. . .|. |||||||||||||.|..|.. |||||.|||..||.|||||.|.||||||..| |.    . .| ||.. |||.||
rWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcv

WQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTPCNF---MYKFWSGM
.||..|||  |||||.|||.| ...|||.||.||..|.||| . .... | |||| | .|. .|||||. ....... . .  ..  .    . |.|| .
yqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWsey

YNRF
| |.
ylrw
subfamily_MTMR1_pd Subfamily MTMR1 123-508 9.2e-138 451.7 In-house 3-387 (389) alignment 
Range on Protein: 123-508
Range on HMM: 3-387/389.0
REQGWVLIDLSEEYTRMGLPNH-YWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSA-RCLEDE
.|.|| . | ..|. |.||.|.  |. ...|..| .||.||. |.|||... . . ....|||. |.||||.. | |.|.| |.||||.| |. |. |||
kedGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskede

QMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCElKSPSMSDFLWGLENSGWLRHIKAIMDAG
..||||..||  |. ....| |.. ||.||.| |||||.|..| |... |. |.||||.|.||.|. |..   . . ...|  ||.. || |||.|... 
kylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvl.pnvddkkwlsalestkWlehiklilaga

IFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLD--GDPKEISPVIDQFIECVWQLMEQFPCAFE
. |...|..| .|||||||||||||||. |.| ||||..|||..|| |||||.|.||||||..|.|. |    ..| |||  |||.|||||..|||.|||
vkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFe

FNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSqtQGTLhLPTTPCnFMYKFWSGMYNRFE
|||.||| .  |.||| ||.||.||.|||.. |..|.| |||... ... .. |||.. . .  .  |  |..    . . |.  | |..
fneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeele..kkvl.ypkasl.rrlelWkeyylrwn
subfamily_MTMR9_pd Subfamily MTMR9 114-506 2.8e-106 347.9 In-house 4-391 (393) alignment 
Range on Protein: 114-506
Range on HMM: 4-391/393.0
FNPMLDKEerEQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFS
.... ..   |.|.   |  .|....  . . | .|.||....|| |||... |||. .   .. |..||.  |||||||. |...| . ||||||.| |
yrsvatil..edgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgss

-ARCLEDEQMLQAIRKANpgsDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRH
  || |||..|... |..      ..|||| |  |...|. | | | |..||..| .   .|..... .||.|.||.|. .. |.. ||  ||.|||| .
gkrckedekllnlvlkkl...kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsq

IKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDP---KEISPVIDQFIECVWQL
......|   .|....||||.|.|| ..| | | || |.| |.|||..||..||. |||..||  || |..|  ..   .   |. .||   |..||.|.
vadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqi

MEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWK--NRADYLNPLFRAdhsqTQGTLHLPTTPCnfMYKFWSGMYNR
..|||..|||||..|| . .| ||.|||.|||....||.|||....| |||... .  .. ..||||. |    .. ..     |.  . ..||..| |
lsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea....naeviwpsvapq..slelWselylr
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 126-482 6.7e-100 326.7 In-house 15-384 (405) alignment 
Range on Protein: 126-482
Range on HMM: 15-384/405.0
GWVLIDLSEEYTRMGL-------PNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFS-ARCL
|| . .  .|| |. .        | ||.....|..|..| ||.. | | . |. . .     |||. | | ||.   .  ||| | |||| |   ||| 
gwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarcp

EDEQMLQAIRKANPgSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELK------SPSMSDFLWG-LENSGWL
|||    ..  . | |  .|..|.||||||.|| | | |.||  || | |. |. | ||||.|.||.|.    .        . |    .|| .|..||.
edelycsslalsap.sktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwi

RHIKAIMDAGIFIAKAVSeEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLM
 |||.|..|  | |. .   | |.||||||||||| |. |.. .||||.|||..|| |||||.|.||||||  | | | |. .| ||...||..|..||.
shiksileaatfsaelil.kgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfqll

EQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQT
.|||  |||   .|. |   |.||..| || | .|.| . ... .| |.|. .  |   .||| .  .  |.
sqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqs
subfamily_MTMR3_pd Subfamily MTMR3 236-480 9.6e-90 294.5 In-house 175-420 (442) alignment 
Range on Protein: 236-480
Range on HMM: 175-420/442.0
VYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCElKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVL
. .|| |    |.|||| | |.|.|. |.| . .|.|. ||| .|.|.... .... .||  |..|  ||.  ||...  .. | . ...||..|| .||
llivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslralls.qspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpvl

VHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDG--DPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYS
||||||||||.|. ..| |||||.||||.|| ||.|..|..|||||. | |. .   | .| .||  |....| || .|||..||||| ||. . .| ||
vhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtys

CQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHS
| || ||.||.|||.| |..||| |.|. | ..  .| | |.. . .
clfGtflansekereeekvkertlsvWsllrakekeyrnllykekte
subfamily_MTMR5_pd Subfamily MTMR5 242-456 6.9e-56 182.0 In-house 205-425 (483) alignment 
Range on Protein: 242-456
Range on HMM: 205-425/483.0
RPKLNAMANRAAGKGYEnEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCEL----KSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVH
. .| .. ...  |...  . .|.. |  . . .|  ...|..|.| .|      ...... ||  .|.| ||. |.....    ... .  .|.|||| 
kaaLYvlgeksqlknvk.sevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvs

CSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPK-EISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQF
  |||| |||| |.| |||||.||||.|| ||.||.|..|||.|..|  .     .  ..||  ||..||.|...||| |||||. .|  . .|  |..|
lEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrf

GNFLCNSQKERRELKI--QERT
  || .|..|| |  .  .|..
rtfllDseyerlesgllyeeka
subfamily_MTMR10_pd Subfamily MTMR10 145-466 1.6e-49 160.7 In-house 25-321 (380) alignment 
Range on Protein: 145-466
Range on HMM: 25-321/380.0
YWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQpLSGFSARCLEDEQMLQAIRKANPGSdfvyvvdtrpk
 .  . .|    .. ..|. ..||.| .   .   |.     |||.... . . .| .  | .     ||   . |.||. .||..|.            
aivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsal.qeaesadkekeekmlelvrkchpan...........

lnamanraagkgyenednysNIKF--QFIGIENIHVMRNSLQKMLEVCELKSPS-----MSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVH
                    ..|.  .   ...|. . .. .|. |.| . ..         .|  ||...||  .....   . ..|.| |.. ||.. 
....................dvklvdlsdelpsiqdvqkaylklreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilq

CSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFG
 |.| |    |.| |.|.|||||||..||  ||.| |.. ||.| .| |... ..|. |||.  | .||.||.|||| .|||.|.||| .  . .|. |.
esegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifl

NFLCNSQKERRELKIQERTYSLWAHLWKN
.||.||...| . . .     .  . .|.
tflfnseeqrlkavvsssplliakselke
subfamily_MTMR3_pd Subfamily MTMR3 129-230 7.7e-25 80.5 In-house 26-129 (442) alignment 
Range on Protein: 129-230
Range on HMM: 26-129/442.0
LIDLSEEYTRMGL-PNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGF-SARCLEDEQMLQAI
  .|.||..|.|.  .. |..|||| |...| |||..| |||| | . .  ...||| .|.|.. . .| | | . |.|||  |. . |. |||..|.||
eeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkai

RKAN
 || 
akac
subfamily_pats1_pd Subfamily pats1 394-479 1.3e-23 75.3 In-house 551-636 (691) alignment 
Range on Protein: 394-479
Range on HMM: 551-636/691.0
EISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADH
  ||.  ||.. ||||  .||  ||||| .|. . .. .| .|||||..  |.. | |. .|. |.|.   .|.. ..| |..   
sfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhsa
subfamily_pats1_pd Subfamily pats1 269-384 4.2e-21 67.0 In-house 339-456 (691) alignment 
Range on Protein: 269-384
Range on HMM: 339-456/691.0
QFIGIENIHVMRNSLQKMLE-VCELKSpSMSDFlWGLENSGWLRHIKAIMDAGIFIAKAVsEEGASVLVH-CSDGWDRTAQV---CSVASLLLDPHYRTL
.|. .   . ...   ..|. . .| . |....   .|.| |.  .| ...| . ... . .|| |||..  .|. . . ..    |.| .|.||.||||
iflslPtrekveerffdllqsilsldg.sddew.keieeskwvdsvkllleaavkvsnll.deGssvllknsidsPlieldlasisslaqvlsdPfyrtl

KGFMVLIEKDWISFGHKFNHR
 ||.|||||.|.|.|. |...
dGfkvliekewlsyGfPfski
subfamily_MTMR5_pd Subfamily MTMR5 134-208 2e-11 35.4 In-house 12-93 (483) alignment 
Range on Protein: 134-208
Range on HMM: 12-93/483.0
EEYTRMGLPN-------HYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQP
 .|.|.|| .        ....| ||..| ||.|||  . ||..   . |   .|   . |.||  .  . | | . ||...
qdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
PTPc_DSPc_SM00012 299-431 2.1e-11 39.3 In-house 38-104 (105) alignment 
Range on Protein: 299-431
Range on HMM: 38-104/105.0
DflwglensgwlrhikaimdagifiakavseeGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTlkgfmvliekdwisfghkfnhrygnldgdpkeispV
.                               ...|.||||.|..||.... .. || . ...|                                    
s...............................skpvvVhCsaGvgRtgtfvaldillqqleket...................................k

IDQFIECVWQLMEQFPCAFEFNERFLIHIQHHI
 ... ..|..|..| | .....| .|. .. ..
evdifqivkelrkqRpgmvqteeqylflyrall
0045098 (Phosphotyrosine protein) phosphatases II 257-385 3.9e-09 31.8 In-house 125-271 (278) alignment 
Range on Protein: 257-385
Range on HMM: 125-271/278.0
YENEDNYSNIKFQFIGIENIHVMRNSLQkMLEVCELKSPSMSDFLWGLEN--SGWLRHIKAIMDAGIFIAKAVSE------EGASVLVHCSDGWDRTAQV
...|......   .. ..|..|.|..|.  ..|. |. ... |. .  ..  . .|.... | .|  ..|. ..       .|  |||||| |..||. .
llseevlddytlrtllvtnltveredle.srgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtl

CSVASLLLD-----------PHYRTLKGFMVLIEKDWISFGHKFNHRY
. .  .|              ..|. ......  .... | ..|  ..
vaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel
0051429 (Phosphotyrosine protein) phosphatases II 286-359 2.5e-07 26.1 In-house 107-178 (272) alignment 
Range on Protein: 286-359
Range on HMM: 107-178/272.0
MLEVCELKSPSMSDFLWGLENSGWLRHIKAImDAGIFIAKAVSEeGASVLVHCSDGWDRTAQVCSVASLLLDPH
.|..  | |....  .. |   .|. |  .  .| . . ... . |  |||||| |.|||. |. .  |||. .
ellltlllsagearevmhlhytdwpdhgvpq.eallellellld.ggpvlvHCsaGkdRTGtvvallllllgvs
Mcm10 Mcm10 replication factor 507-609 4.1e-07 15.9 Pfam-A 21-123 (344) alignment 
Range on Protein: 507-609
Range on HMM: 21-123/344.0
FEKGMQPRQSVTDYLMAVKEETQQLeEELEALEERLEKIQKVQLNCTKVKSKQSEPSKH-SGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALIL
 ||. || .|..   .  ... ..| | |||...| |.|||  |. .. ..|.|..|   ..  .| .. ...|.     ...  .   |.| . |  ||
aekagqpkksisasellkqqkkkdl.erlearkkraeeiqkrvLqssekeeksskasssakstlqspkaaselpkarkfsleaaatPklsrgfsesedil

TQDN
  |.
ladk
subfamily_pats1_pd Subfamily pats1 133-209 7.7e-07 19.8 In-house 12-90 (691) alignment 
Range on Protein: 133-209
Range on HMM: 12-90/691.0
SEEYTRMGLPNHY-WQLSD-VNRDyrVCDSYPTELYVPKSATAHIIVGSSKFRSrRRFPVLSYYYKDNHAS---ICRSSQPL
  |. |..|     |.  . ..||  ... ||    |||. . ...| . . ||  ..||||.  ..| .|   ||   ||.
liegqrlkldldkdwrvveflsrd..lseiyPkrilvPklvsdellvsyvrkrs.skiPvlswsnqnnksslfricvynqpf
0044763 (Phosphotyrosine protein) phosphatases II 322-351 8.3e-07 24.3 In-house 101-130 (178) alignment 
Range on Protein: 322-351
Range on HMM: 101-130/178.0
FIAKAVSEEGASVLVHCSDGWDRTAQVCSV
|| .|..|.|  |||||| |..|.. ..  
fieealdekggpvlVHCsaGvgRsgtlvaa
subfamily_MTMR14_pd Subfamily MTMR14 325-385 1e-06 19.8 In-house 261-328 (357) alignment 
Range on Protein: 325-385
Range on HMM: 261-328/357.0
KAVSEEG-ASVLVHCSDGWDRTAQVCSVA--SLLLDPH-YRTLKGFMV---LIEKDWISFGHKFNHRY
| |.|.. . .||||  |||||    |.   ||  | . ...|.   .    .  ||  |||.. .| 
kyvkededsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrl
0049772 (Phosphotyrosine protein) phosphatases II 316-356 1.1e-06 24.2 In-house 199-237 (314) alignment 
Range on Protein: 316-356
Range on HMM: 199-237/314.0
IMDAGIFIAKAvsEEGASVLVHCSDGWDRTAQVCSVASLLL
. ..  || .|  ..|  |||||..|..||.  . .| |..
fdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmk
0051082 (Phosphotyrosine protein) phosphatases II 322-356 3.9e-06 22.1 In-house 83-117 (151) alignment 
Range on Protein: 322-356
Range on HMM: 83-117/151.0
FIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLL
|. .. . ..  |||||| |..||. .. .  .||
flellldkkngpvlvHCsaGkgRTGtlvalylmll
DUF972 Protein of unknown function (DUF972) 506-562 5.5e-06 13.2 Pfam-A 16-66 (107) alignment 
Range on Protein: 506-562
Range on HMM: 16-66/107.0
RFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKvqlnctKVKSKQSEP
. |. ..  ... . | .. || ..|. | |.|.||||....      . |.|... 
qleellkeleelkkelaelleenaelkleneklrerleelee......eekkkekkk
DUF342 Protein of unknown function (DUF342) 523-576 7.5e-06 10.8 Pfam-A 331-381 (451) alignment 
Range on Protein: 523-576
Range on HMM: 331-381/451.0
AVKEETQQLEEELEALEERLEKIQKVqlnCTKVKSKQSEPSKHSGFSTSDNSIA
..||....||||||.|||.|||..|     .|..... |.   | .. . ... 
elkeklkeleeeleeleeeleklkkk...lkklpklkaegqlesekkeqlekll
GRAM GRAM domain 24-60 8.7e-06 16.6 Pfam-A 30-67 (69) alignment 
Range on Protein: 24-60
Range on HMM: 30-67/69.0
ALGTLYLTATHVIFVENSPDPRK-ETWILHSQISTIEK
. |.|||| ...||  ...|. |    |  ..|. .||
vqGrlYlTnyrliFrSdklddskvvvvipladikrvek