Gene DNAJC6 in Homo sapiens

Synonym: DJC6, PARK19, DNAJC6

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTEN
Subfamily Auxilin
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP062_AA protein Get Run
HsapP062_AA_104-280 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Auxilin_pd Subfamily Auxilin 113-278 2.7e-84 273.9 In-house 1-166 (166) alignment
Range on Protein: 113-278
Range on HMM: 1-166/166.0
VTSYTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQN
|.||.|.|||..|.||||||||||...|.....|..||.||||.||| ..|.|||||...|||||..|||.|..||.|.||.|..|..||||.|.|| ..
vasyakndlDisyitsriivmsfPaegvestyknniddvrsfLesrhpekylvynlsqrtyrtaklssrvveagwparraPnLeslvevcrnlyswlkkd

PKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLAD
||||.|||| ||||||..||.|...||.|.|.|  |.||...|| .||||||..||| |..||||.
pknvvvvhckDGraasavlvsallvfcrllsepesavrlfsvkrlpiglspsekryleyladllae

PTEN_1 107-278 5.9e-39 128.9 In-house 6-194 (196) alignment
Range on Protein: 107-278
Range on HMM: 6-194/196.0
SRVIQSVTSYTKGDLDFTYVTSRIIVMS-FPLDN-----VDIGFRNQVDDIRSFLDSRHLDH-YTVYNLSPKS------YRTAK-FHSRVS--ECSWPIR
 |. ..  .... .||.||.|||||.|. .| ..      .  .|....|....||... |. ..|.|||...      |.  . |.|.|.  .....  
krsskknlalptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDh

QAPSLHNLFAVCRNMYNWLLQNP-KNVCVVHCLDGRAASSILVGAMFIFCNLySTPGPAIRLLYAKR-PGIGLSPSHRRYLGYMCDLLAD
.||||. ||..|... .|||..| .||..|||  |.  |  .| |  ....  .|.  |..|...|| ||   |||..|.| |  .||| 
gapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk.ltadeAlelvrekRppgapnspsqerlleyfaellae

subfamily_Tensin_pd Subfamily Tensin 118-279 8.5e-39 126.0 In-house 8-174 (189) alignment
Range on Protein: 118-279
Range on HMM: 8-174/189.0
KGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVC
| ||| ||.|.|||..||| . ..  .|... |.  .|.|.| |.| |.||| |.|   |....| .  ||  .||||  | ..|... .|| ..|.|| 
kvdldltyiteriialsfpaegleekyrenlkdvakllkskhndkylvfnlsekrydisklnkkvldfGWPdllaPsleklcsicksldsWlkadpqnvv

VVHCLDGRAASSILVGAMFIFCNLYSTPGPAI-----RLLYAKRPGIGLSPSHRRYLGYMCDLLADK
||||  |.   ...| |   . .. ..   |.     . .. ..    . ||.|||. |. .||..|
vvhckGgkgrigvvvsaymkyskisasadaaldrfamkrflddklsgetqPsqrryveyfsglLsgk

subfamily_PTEN_pd Subfamily PTEN 116-277 4.3e-36 119.6 In-house 15-180 (184) alignment
Range on Protein: 116-277
Range on HMM: 15-180/184.0
YTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPK
. . ||| .|.|..||.|..| ....  .||...|.  ||...| ||| .||| | ..| ..||..||...     ..|.|. | ...... .|| ...|
edgldLDlsyiteniiamgyPaeklealyRnsledvvkflekkhkdhykiynlrserkydskkfdgrvavypfdDhnppplelleeivediekwleedkk

NVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGI--GL-SPSHRRYLGYMCDLLA
|| ||||  |.  . .|. | .. ..|....  |..|  ..|     |.  || |||. |. .|| 
nvvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaRtknkkgvtiPsqrRYveYyeklle

PTEN_C2 C2 domain of PTEN tumour-suppressor protein 284-420 4.3e-30 95.6 Pfam-A 2-132 (134) alignment
Range on Protein: 284-420
Range on HMM: 2-132/134.0
HFKPLTIKSITVSPIPFFnKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSMYHLRSTigsrlqaKVTNTQIFQLQFH
. |.|..|||....||.| |.|.||.|.. |  |..|. ....... ..|.| ..  . .| ...|.|||.| ..| .|.       .... .||...|.
npkrlelksiilegiPnf.ktrggckpkvkvyngkkkvfkelasykdsterraktfivkepnrlpveGDvlveflhkdsk.......lpkkekifrvwFN

TGFIPLDTTVLKFTKPELDACDVP--EKYPQLFQVTLDV
| ||. ...||...| ||| ..    .|... |.|.| .
TsFieknqnvltlpkneLDkalkdkdkkfsknfkvelvf

subfamily_VSP_pd Subfamily VSP 110-272 3.7e-29 96.2 In-house 21-194 (212) alignment
Range on Protein: 110-272
Range on HMM: 21-194/212.0
IQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMY
 .    ||.   |||.|||| ||| ||||    .  .|| ....  ||| .| ||| |.|| | ..|  . |. ||...     . |.|..|. ..... 
senkrrytqdGfdldltyvteriiamsfpssGkqslyrnpisevarfldtkhrdhykvvnlcseraydekyfnnrvkriliddhnvpkleellvftkevk

NWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGL--------SPSHRRYLGYM
.|| ...||| ..||  |.  .  .| |...  ....|   ..  .  .|   .         .|| .||.||.
ewlekdlknvlaihckGGkgrtGtivcalllaseifetakesldyfgerrtdktegekfqGvqtpsqkryvgyl

0036282 (Phosphotyrosine protein) phosphatases II 120-276 9e-28 92.5 In-house 9-169 (174) alignment
Range on Protein: 120-276
Range on HMM: 9-169/174.0
DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPK-SYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCV
.||..|.|.|.|....||....  ..... .. ..|....|..| ..|. |  ..   ... ..  . || ...|.|. |. ... ....|...|.....
pldlsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvl

VHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKR---PGIGLSPSHRRYLGYMCDLL
|||  |.  . .||.|. . ..|....  |..|....|   ||.  .||..|.| |...||
VHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll

0038934 (Phosphotyrosine protein) phosphatases II 125-280 1e-18 63.2 In-house 15-180 (194) alignment
Range on Protein: 125-280
Range on HMM: 15-180/194.0
YVTSRIIVMSFPLDN-----VDIGFRNQVDDIRSFLDSRHLDHYTVYNLS--PKSYRTAKFHSR-VSECSWPI---RQAPSLHNLFAVCRNMYNWLLQNP
..| |.|....||..     ..   |. ..|. ..|.... ....|..|.   . | . .|... .   ..|.     .||| .|.  .. .. .| ..|
iitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedp

KNVCVVHCLDGRAASSILVGAMFIFCNLYsTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKP
..|..|||  |.  . .||.|  | .. . ..  ||.|.  ||||.  ...  ..|    . | ...
ggvvaVHCkaGlgRtGtlvaaYLiyrlgm.saeeAialfrekRpgaipnqdyleallkrykelrkav

0046846 (Phosphotyrosine protein) phosphatases II 118-276 9.1e-17 56.8 In-house 7-172 (176) alignment
Range on Protein: 118-276
Range on HMM: 7-172/176.0
KGDLDFTYVTSRIIVMSFP-----------LDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKsyrTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMY
  |||..|.. ..|..|.|            |...  ...... . .... ..|... ..|. |      |.. ..  . ||  ..|.|  |. ... ..
gldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgiqylhlpwpDhgvpdlelllellefir

NWLLQNpkNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRP-GIGLSPSHRRYLGYMCDLL
..| ..  .. .|||  |.  .  || |  . ..   ..  |..|. ..|| |.  .|...|.| ..  ||
ealkeg..gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll

0039614 (Phosphotyrosine protein) phosphatases II 116-272 1.6e-16 56.1 In-house 78-284 (297) alignment
Range on Protein: 116-272
Range on HMM: 78-284/297.0
YTKGDLDFTYV-----------TSRIIVMSFPLDNVDIGFRNQVDDIR---------------------------------SFLDSRHLDHYTVYNLSPK
. . ||| .|.           | ..|....||..    | . | . .                                  .|.  |||.|||..|. .
edgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevt

SYRTAKFHSRVSECSWPIRQAP-SLHNLFAVCRNMYNWLLQN-PKNVCVVHCLDGRAASSILVGAMFIF----CNLYSTPGPAIRLLYAKRPGIGLSPSH
 .   ... ..   .||  ..| ||  |. ... . ..| .. ......||| .|   .  ...|  ..    ..   ..  |.. |  .|||.  .||.
nngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsq

RRYLGYM
 |.| ..
yrflyda

0043147 (Phosphotyrosine protein) phosphatases II 120-271 1.9e-15 52.5 In-house 12-155 (172) alignment
Range on Protein: 120-271
Range on HMM: 12-155/172.0
DLDFTYVTSRIIVMSFPldnvdigFRNQVDDIRSFLDSRHLDHytVYNLSPK---SYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNV
.||..|.. |.|.. .|       .|| ..| . .| ... .|  ..|| .     .   ..  ..  ..||   .|.|  |  ... ....|...|...
yldlyyipdrfiatqgp.......lrntladfwrmlkelgith..ivnltellydpellerlgiqylylpwpDhgvpllellleflefidellalspggp

CVVHCLDGRAASSILVGAMFIFCNLysTPGPAIRLLYAKRPGIGLSPSHRRYLGY
..|||  |   .  || |  . ..|  ..  |..|. .||||.  .||..|.| |
vlVHCsaGvgRtgtlvaaylmllgl..sleeavalvrekRpgavqnpsqyrflyy

0037934 (Phosphotyrosine protein) phosphatases II 107-272 4.4e-15 51.4 In-house 25-237 (243) alignment
Range on Protein: 107-272
Range on HMM: 25-237/243.0
SRVIQsvTSYTKGDLDFTYVTSRIIVMSFPLDN----VDIGFRNQVDDIR---------------------------------SFLDSRHLDHYTVYNLS
|||.    .    .....||| |.|....||..    ..  | . . . .                                  .|...|||.|||..|.
srvkl..egsdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtll

PKS---YRTAKFHSRVSECSWPIRQAPS-LHNLFAVCRNMYNWLLQ-------NPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPG
 .    .   ... ..   .||  ..|.   .| . .. ..... .       .......|||  |.  .  |. |  .  .|  ..  |..|| ..|||
lenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpg

-IGLSPSHRRYLGYM
 .  .||..|.| ..
kavqtpsqyrflyea

0051082 (Phosphotyrosine protein) phosphatases II 119-267 1.7e-14 49.2 In-house 4-143 (151) alignment
Range on Protein: 119-267
Range on HMM: 4-143/151.0
GDLDFTYVTSRIIVMSFPLDnvdigfrnqvdDIRSFLdsRHLDHYTVYNLSPKS---YRTAKFHS---RVSECSWPIRQAPSLHNLFAVCRNMYNWLLQN
. ..|.|||........||.           |   .|  ..|...|..|| ..    | .  ...   .|  . ..  ..|.|  .|. .... ..||..
dyinfsyvtgglyrsggpla...........dflell..kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldk

PKNVCVVHCLDGRAASSILVGAMFIFCNlySTPGPAIRLLYAKRPGIGLSPSHRR
......|||  |.  . .||... . ..   ..  |.. . .||||.  .. ...
kngpvlvHCsaGkgRTGtlvalylmllg..vsleealeeyrlkrpgvvqpnqqfl

0043336 (Phosphotyrosine protein) phosphatases II 106-271 3.1e-14 48.6 In-house 59-271 (278) alignment
Range on Protein: 106-271
Range on HMM: 59-271/278.0
SSRVIQSVtsyTKGDLDFTYV----------TSRIIVMSFPLDNVDIGFRNQVDDIR----------------------------------SFLDSRHLD
.|||. |.   ..|||| .|.          . ..|....||..    |.. | . .                                   .|.  |||
hsrvklsl...lggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehld

HYTVYNLSPK--SYRTAKFHSRVSECSWPIRQAP-SLHNLFAVCRNMYNWLLqNPKNVCVVHCLDGRAASSILVGAMFIF----CNLYSTPGPAIRLLYA
.|||..|  .   .   ... ..   .||  ..| ||  |.  .. . ..|  ..... .||| .|   .  ....  ..     ..  ..  |.. |  
dytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelre

KRPGIGLSPSHRRYLGY
.|||.  .||. |.| .
qRpgavqtpsqyrflye

0042113 (Phosphotyrosine protein) phosphatases II 116-271 2.1e-13 45.7 In-house 30-237 (245) alignment
Range on Protein: 116-271
Range on HMM: 30-237/245.0
YTKGDLDFTYV----------TSRIIVMSFPLDNvdigfrnqvdDIR---------------------------------------------SFLDSRHL
 ..|||| .|.          | ..|....||..          ..                                               .|.  ||
pdggdldsdyinasyvdgyritpkfiatqgPlpe..........tvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehl

DHYTVYNLSPK--SYRTAKFHSRVSECSWPIRQAPS-LHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIF----CNLYSTPGPAIRLLY
|.|||..|. .   .   ... ..   .||  ..|. |  |. ... . ..| ........||| .|.  .  ...|  ..     .|  ..  |.. | 
ddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelr

AKRPGIGLSPSHRRYLGY
 .|||.  .||. |.| .
sqRpgavqtpsqyrflye

0040439 (Phosphotyrosine protein) phosphatases II 105-271 5.3e-13 44.6 In-house 24-240 (249) alignment
Range on Protein: 105-271
Range on HMM: 24-240/249.0
TSSRVIQSVTSYTKGD-------LDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIR-----------------------------------SFLDSRHLDH
 .|||. |...   ..       .|..|.. |.|....||..    |.... . .                                    .|.  ..|.
dhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkdd

YTVYNLSPKS-YRTAKFHSRVSEC-SWPIRQAP-SLHNLFAVCRNMYNWLLQN-PKNVCVVHCLDGRAASSILVGAMFIF----CNLYSTPGPAIRLLYA
|||..|  .  |   ... ..  . .||  ..| |.  |.. .. . ..| .. ......||| .|   . ....|  ..     .|  ..  |..||  
ytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrs

KRPGIGLSPSHRRYLGY
.|||.  .|.. |.| .
qRpgavqnpeqyrflye

0046845 (Phosphotyrosine protein) phosphatases II 106-272 1.4e-12 43.0 In-house 42-269 (284) alignment
Range on Protein: 106-272
Range on HMM: 42-269/284.0
SSRVIQSVTSY------------TKG-DLDFTYVTSRIIVMSFPLDN-----------------------------VDIGFRNQVDDIRSF-------LD
.|||. ....              .| |||.||.. ..|....||.|                                 .... ..   .       |.
hsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtlls

SRHLDHYTVYNLSPKS---YRTAKFHSRVSECSWPIRQAP-SLHNLFAVCRNMYNWLLQ-NPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTP------
  . |.|||..|. .        ...      ||| ...| |. .|.. .| . ..| . ..... |||| .|   .  .. .. ... |  .       
eevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvd

-GPAIRLLYAKRPGIGLSPSHRRYLGYM
   |.. |  .|||   .... |.. ..
vleavkrlreqRpgmvqtleqyrfvyea

0041856 (Phosphotyrosine protein) phosphatases II 120-271 3.6e-12 41.7 In-house 16-165 (182) alignment
Range on Protein: 120-271
Range on HMM: 16-165/182.0
DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHY-TVYNLSPKSYRTAKFHS---RVSECSWPIRQAPSLHNLFAVCRNMYNwllqnPKN
..|..|.. .....|.| ..  .  ..  ... .||.  .  .. |. ||..  |   ...    ..   .||   .|.|. |.. .. ...     ...
srdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpdldelldfieevle.....egg

VCVVHCLDGRAASSILVGAMFIFCNlYSTPGPAIRLLYAKRPGIGLSPSHRRYLGY
...|||  |.  .  ||.| .. ..   ..  |..|.  .|||.  .|.. ..| .
pvlVHCsaGvgRtgtlvaaylmkkl.gvsleeavklvrsrRpgmvitpnqyfflql

0049260 (Phosphotyrosine protein) phosphatases II 144-271 5.8e-12 41.0 In-house 18-144 (152) alignment
Range on Protein: 144-271
Range on HMM: 18-144/152.0
FRNQVDDIRSFLDSRHLDHYTVYN-LSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFcnLY
 .| ..|   .| . . ... ... |... .   ... ..  . ||   .|.|. |.  .  . ..|.........|||  |   .  || |  .   | 
gpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml..lg

STPGPAIRLLYAKRPGIGLSPSHRRYLGY
 ..  |..|. .||||.  .|...|.| .
vsleeavalvrekRpgavpnpgqlrflye

0040438 (Phosphotyrosine protein) phosphatases II 116-273 2.4e-11 38.9 In-house 64-272 (317) alignment
Range on Protein: 116-273
Range on HMM: 64-272/317.0
YTKGDLDFTYV----------TSRIIVMSFPLDNVDIGFRNQVDD-----IRSF------------------------------LDSRHLDHYTVYNLSP
 ..|||| .|.          . ..|....||.|    | . | .     | ..                              |.  .|...|...|  
plggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlev

KS-YRTAKFHS-RVSECSWPIRQAP-SLHNLFAVCRNMYNWLLqNPKNVCVVHCLDGRAASSILVGAMFIF----CNLYSTPGPAIRLLYAKRPGIGLSP
.  .   ...       .||   .| |.  |.. .. . ..|  .|.....||| .|   .  ...|  ..     .   ..  |.. | ..|||.  .|
edlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtp

SHRRYLGYMC
.. |.| .. 
eqyrflydal

0048076 (Phosphotyrosine protein) phosphatases II 144-272 3.6e-11 38.4 In-house 12-138 (145) alignment
Range on Protein: 144-272
Range on HMM: 12-138/145.0
FRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSL-HNLFAVCRNMYNWLLQNpkNVCVVHCLDGRAASSILVGAMFIFCnLY
... . . ...   ..|...||.||..  .   ... ..  ..|| ...|.|   | .... . ..| ..  ....|||  |.  .  ||.|. ... | 
ylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlvaaylmll.lg

STPGPAIRLLYAKRPGIGLSPSHRRYLGYM
 ..  |..|. ..|||.  .|...|.| . 
vsleealelvrsqrpgavpnpgqlrflyef

0048179 (Phosphotyrosine protein) phosphatases II 144-271 1.1e-10 37.0 In-house 12-139 (144) alignment
Range on Protein: 144-271
Range on HMM: 12-139/144.0
FRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHS--RVSECSWPIRQAPSL-HNLFAVCRNMYNWLLQNpkNVCVVHCLDGRAASSILVGAMFIFCN
... . . ...   ..|...||.||... . .   .   ..  ..|| ...|.| . | .... . ..| ..  ....|||  |.  .  || |  ....
ylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg..gpvlVHCsaGvgRtgtlvaaylmkkl

LySTPGPAIRLLYAKRPGIGLSPSHRRYLGY
   ..  |..|. ..|||.  .|...|.| .
g.lsleealalvrsrrpgavpnpgqlrfLle

0045450 (Phosphotyrosine protein) phosphatases II 124-271 1.5e-10 36.8 In-house 142-298 (307) alignment
Range on Protein: 124-271
Range on HMM: 142-298/307.0
TYVTSRIIVMSFPLDNVDIGFRNqvdDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSEC---SWPIRQAP-SLHNLFAVCRNMYNWLLQN-PKNVCV
.. ....... .|...  . ..|   .   .|.  |||.|||..|  . ..  ... .|      .||  ..| |.  |.. .. . ..| .. ......
velgrekcaqywPdegeeltygn...ftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvl

VHCLDGRAASSILVGAMFIFCNLY-------STPGPAIRLLYAKRPGIGLSPSHRRYLGY
||| .|   .  ...|  . ..|         ..  |..|| ..|||.  .|.. |.| .
VHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflye

DnaJ DnaJ domain 918-965 5e-10 28.3 Pfam-A 13-58 (64) alignment
Range on Protein: 918-965
Range on HMM: 13-58/64.0
TPEQVKKVYRKAVLVVHPDKATGQPyeQYAKMIFMELNDAWSEFENQG
. |..|| ||| .| .||||. ...  . |.  | |.|.|..  ... 
sdeeIkkaYrklalkyHPDknkdde..eeaeekfkeineAyevLsdpe

0047943 (Phosphotyrosine protein) phosphatases II 154-270 6.6e-10 34.4 In-house 141-265 (273) alignment
Range on Protein: 154-270
Range on HMM: 141-265/273.0
FLDSRHLDHYTVYNLSPKS--YRTAKFHSRVSECSWPIRQAP-SLHNLFAVCRNMYNWLLQN-PKNVCVVHCLDGRAASSILVGAMFIF----CNLYSTP
.|.  . |.|||..|  ..  .   ..   .   .||  ..| ||  |.  .. . ..| ..  ... |||| .|   .  .. .  ..    ..   ..
llseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdv

GPAIRLLYAKRPGIGLSPSHRRYLG
  |..||  .|||.  .|...|.| 
leavkllrsqRpgmvqtpeqyrfly

0045098 (Phosphotyrosine protein) phosphatases II 150-271 8.3e-10 34.0 In-house 127-266 (278) alignment
Range on Protein: 150-271
Range on HMM: 127-266/278.0
DIRSFlDSRHLDHYTVYNLSPKSYRTAKFHSRVSEC-SWPIRQAPSLH---NLFAVCRNMYNWLL------------QNPKNVCVVHCLDGRAASSILVG
..  . |  .| ...|.||. . .   ... ..  . .||   .|||.    .. ... . ..|             ........|||  |   .  ||.
seevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlva

AMFIFCNL--YSTPGPAIRLLYAKRPG-IGLSPSHRRYLGY
|. . ..|    ..  |.. |  .||| .  .... |.| .
aylmlelleggvdlleavkelrsqRpglavqnleqyrflye

0051299 (Phosphotyrosine protein) phosphatases II 154-269 3.2e-09 32.1 In-house 153-278 (288) alignment
Range on Protein: 154-269
Range on HMM: 153-278/288.0
FLDSRHLDHYTVYNLSPK------SYRTAKFHSRVSECSWPIRQAPS-LHNLFAVCRNMYNWLLqNPKNVCVVHCLDGRAASSILVGAMFIFC----NLY
.|.  .||.|||..|  .         . ..       .||  ..|. .  |.. .| ....|  ......|||| .|   .  .. .  ...    .  
llseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekegg

STPGPAIRLLYAKRPGIGLSPSHRRYL
 ..  |.. |  .|||.  .|.. |..
vdvleavkrlreqRpgmvqtpeqyrfv

0044763 (Phosphotyrosine protein) phosphatases II 120-273 1.1e-08 30.5 In-house 20-167 (178) alignment
Range on Protein: 120-273
Range on HMM: 20-167/178.0
DLDFTYVTSRIIVMSFPLdnvdigfrnqvDDIRSFLDSRHLDHytVYNLSP---------KSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLL
 ....... .....|.|             | . .|   ...|  . ||..           |   ... ..  . .|   .|.|   |  . .. . .|
yinaseilpglylgslpp...........addlellkelgith..ivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeal

QNPKNVCVVHCLDGRAASSILVGAMFIFCNLYsTPGPAIRLLYAKRPgIGLSPSHRRYLGYMC
........|||  |.  |  || |  . .. . ..  ||.|. ..|| |  .|...|.| .. 
dekggpvlVHCsaGvgRsgtlvaaylmkklgl.sleeaielvrerRp.ivpnpgqlrqLyefe

0049772 (Phosphotyrosine protein) phosphatases II 127-267 1.7e-07 26.8 In-house 120-264 (314) alignment
Range on Protein: 127-267
Range on HMM: 120-264/314.0
TSRIIVM---------------------SFPLDNVDigfrnqvddirSFLDSRHLDHYTvynlsPKSYRTAKFHSRVSEC---SWPIRQAPSLHNLFAVC
 .|.|||                       .||              .... ..|...      .  |   .|  .. .     .|  .||.|  . ...
nvrdivmsrdevladelsrLdaAlgKtpllildgng...........neptaadlellk.....eelydpelferlgikylripvpDgsaplledfdefl

RNMYNWllqNPKNVCVVHCLDGRAASSI-LVGAMFIFCNLYsTPGPAIRLLYAKRPgIGLSPSHRR
. . ..   ..... .||| .|.  .   .| |. . .. . ..  |.. . .||| |. .|. ..
efieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRp.inpnpgfie

0050432 (Phosphotyrosine protein) phosphatases II 156-269 4.4e-07 25.0 In-house 161-291 (308) alignment
Range on Protein: 156-269
Range on HMM: 161-291/308.0
DSRHLDHYTVYNLSPKSYRTAKFHSRVSEC---------------SWPIRQAPS-LHNLFAVCRNMYNWLlqnPKNVCVVHCLDGRAASSILVGAMFI--
.|.. ...||..|| ... . .      ..               .||  ..|. .  |.. .. . ..|   |....|||| .|   .  .. .  .  
gsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllle

--FCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYL
   ..   ..  |.. |  .|||   .|.. ..|
qlekeggvdvfeavkklReqRpgmvqtpeqylfl

0036941 (Phosphotyrosine protein) phosphatases II 158-275 2.6e-06 22.4 In-house 145-274 (297) alignment
Range on Protein: 158-275
Range on HMM: 145-274/297.0
RH--LDHYTVYNLSPKS--YRTAKFHSRVSECSWPIRQAPS-LHNLFAVCRNMYNWLLQN-PKNVCVVHCLDGRAASSILVGAMFIFCNLY-------ST
 .  ||.||...|  .   .   ..       .||   .|.    |.. .. . ..| .  .... .||| .|   |  ...|  ... |         .
evvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvd

PGPAIRLLYAKRPGIGLSPSHRRYLgYMCDL
.  |.. |  .|||.  .... |.| |.. |
ileavkklReqRpgavqtleqyrfl.yeall