Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRD_pd | Subfamily PTPRD | 1344-1674 | 2e-169 | 559.9 | In-house | 2-333 (564) | alignment | ||
Range on Protein: 1344-1674
Range on HMM: 2-333/564.0
HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLP
..|||...|.. ...||||..|||..||..|..|||||||..| ..||.||||||..|||||||.|....|..|||||||..||||||..|||||||||.
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPla
ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILA
||. |||||||||...|.||.|.||||..|||..|||..||||.| ..||| ...|||.|..||| |.|. |||.|| |||.|..||||||||..|..|.
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLd
FLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG
..|.|.|.|. ||||.||||||||||||.||||||||||.|.|||||||..|...|.|||.|||||.||.|||||.||| .||.|||...||..|.|||
lirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkLa
QVPPGESVTAMELEFKLLA-SSKAHTSRFISA
.| .....| .||||. || ... ....| .|
eveedtemtgleleFqrLatakeieleefava
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1347-1660 | 2.3e-131 | 432.6 | In-house | 2-317 (318) | alignment | ||
Range on Protein: 1347-1660
Range on HMM: 2-317/318.0
IPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPET
|.. ||.....||... |..|.||| ... ...|. .|. .||| ||||||..||||.|| |. ..|..||||||||||||||...||||.|.|||||
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
MGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFL
. ||||||||| .|..||.|..||....|...||| .|... | ..|.| ..|||..|..|.| .......|.|. ||... .|||.|||| .. .|...
ieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlv
RRVKACN-PLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQ
|.|.. . . .|||.|||||||||||| ||..|..|||.|.|..||... |. .|.||| ||||||||.||...|||| ..|.||| |..| ..|..| .
rqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelre
VPPGESVTAMELEFKL
. | | |..||.
qdpesgttemdaefqr
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1667-1919 | 8.4e-127 | 419.1 | In-house | 36-286 (564) | alignment | ||
Range on Protein: 1667-1919
Range on HMM: 36-286/564.0
HTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQ
..... .|| |.|| |||. ||..|. .||.|....|.||||||||||.||||..||||||||||||..||||||.||.||..|||||||.|.|..|||.
qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchk
YWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRTGVFIT
|||......|....|....|... .|..|.||...... .||..|||.||.||..|||.......|.| .|....| . |||.|||||||||||.||.
YWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne..pdagPivVhCSaGVGRTGtfiv
LSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH
....|||...|..||..|.||.||.||.||||||.||. ...| ||.| ...
idamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1346-1659 | 1.5e-116 | 384.0 | In-house | 4-319 (319) | alignment | ||
Range on Protein: 1346-1659
Range on HMM: 4-319/319.0
PIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPET
.|.. .|......|... .. .|.. .. ....|..... | ||.|||| |..|||..||.|...|||.|||||||..||||......||||.|| .|
eievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlent
MGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHK-SGSSEKRELRQFQFMAWPDHGVPEYPTPILAF
. ||||||||... .|||.|.| || .||. .||| |. | . |||.. ||. | .| . |.| |. | ||. .||...||||.|||. | .|..
iedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldl
LRRVKACNP-LDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG
|.|.. ..||.|||||||||||| |||.||||||.|.| ..|.. | .| ||| |||...|| ||.||||||...|.||. ..| ...|
lkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqla
QVPPGESVTAMELEFK
. .. | .| ||.
ekvadtgetglerefq
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1652-1921 | 9.1e-114 | 374.8 | In-house | 20-287 (318) | alignment | ||
Range on Protein: 1652-1921
Range on HMM: 20-287/318.0
TAMELEFKLLASSKAHTSRFISaNLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIV
. .. |.. |. |....... | . |.||.||| .||..|. ||| ||.. |.||||||||...||||..|||||.|.||.| ||||||.|| ||..||
lllseeyerlsrseetvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsaviv
MLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQdGPIT
|||...| |..|.|.||| . | |. ||. . | .. .|.||||||| .||..||...|.||..|||. | ...|...||.|.... |. |||.
mltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksga.gpiv
VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA
||||||||||||||...|.|||.. |..||.|||||.||.||..||||||||...| . ||.| |.| ..
vhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1339-1658 | 9e-112 | 368.2 | In-house | 6-330 (330) | alignment | ||
Range on Protein: 1339-1658
Range on HMM: 6-330/330.0
SSMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIA
|. . ..|.|. .| ..|.. .|.| .| .|.... | | | .. | || |||. |.. ||.|||||. ..||. |||||| .||||.... .||
sgnkkyfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfia
TQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSS----EKRELRQFQFMAWPDHG
.|||. ||. |||||.|||..||.||.| |.|. . || |||| |. | | |.|.. |...| |||| | ... . . ..| .||| | .||| |
aqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvG
VPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPAR
|| | .| .|..||..|. |||.|||||||||||| |||.||.|||.| |. ||... | .| || ||||. ||.||...||| | ||. .
vPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvs
NLYAHIQKLGQVPPGESVTAMELEF
| |.||| . .| . ...| ||
slekhlqklynkitgtdkigleeef
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1349-1661 | 1.4e-111 | 368.0 | In-house | 2-314 (317) | alignment | ||
Range on Protein: 1349-1661
Range on HMM: 2-314/317.0
ITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGD
..|| . ...|...| ....|.| .. . |.. ..|..||.|||| ... ||||||.|....|...||||||.|.||.......||||||||.|..|
vldlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntved
FWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRV
||||||||.. ..||.|.|||..|.||.|||| ..| |.| ..||||...||| .|.||. . ..|.||.|....|....|||||||..|...|.||..|
FwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleav
KACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPG
..... . ||..|||||||||||.||... |||....|..||.. | .|.||...|||..||.|...|||| ....| .|| .|. ...|| .....
realedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllklliplal
ESVTAMELEFKLL
..|. .| |.|||
ddvklkekelkll
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1347-1635 | 1.6e-111 | 368.3 | In-house | 1-299 (563) | alignment | ||
Range on Protein: 1347-1635
Range on HMM: 1-299/563.0
IPITDLADNIERLKANDGLKFSQEYESID---PGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGS-DYINANYIDGYRKQNAYIATQGPL
.|. ..| . |.|.. .||.|.|.. .... | |. . || |||| |..|||.||| |... |. .. |||||||||||.|..|.|||||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgpl
PETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHK----SGSS--EKRELRQFQFMAWPDHGVPE
..|. |||||.|||..|..||.| |.|. | |||.|||. ..||.| .|||| .. ||.|||||. ... ... .... ||... ||||||||
kdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPe
YPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNL
...| | | .. .| |. .|||.|||||||||||| .||.|..|.....|..|...| . .|.|||..||||.||.|.|.||||| . ..||. | ..
hslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqv
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1344-1645 | 7.2e-110 | 361.7 | In-house | 1-299 (314) | alignment | ||
Range on Protein: 1344-1645
Range on HMM: 1-299/314.0
HPPIPITDLADNIERLKANDGLKFSQEYESIDPGqqftWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLP
|| | . || ..| ||...| | .||||. | |. .. . |. |||. ...|||.|||.|..||| | ||||||..||.|.. .|.|.|||||.
hpairvadllqsiallkraegygfkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlq
ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTEtCGLIQVTLLDTVELATYTVRTFALHK--SGSSEKRELRQFQFMAWPDHGVPEYPTPI
||. ||||.|.....|..||.| | |..|||| .||| .. | |.|.|..| || . ||.|...| | .|.||.|||||..||||.|| . | .
etvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgl
LAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQK
|...||||. .. .||..||||||| ||||.||.|| .|. ...|..||.. | .||.. ||.||.||.||....|||. ||.| .|. .. | .
lklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalyle
LGQV
..
sirl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1344-1623 | 1.9e-108 | 357.6 | In-house | 2-286 (288) | alignment | ||
Range on Protein: 1344-1623
Range on HMM: 2-286/288.0
HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPL
. .|....|.. ...|.||. .. .|.| . . . ..|. ..|. |..|||| ....||||||.|...|||.|||||||.|||||......|||||||
dteisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPl
PETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKS----GSSEKRELRQFQFMAWPDHGVPEYP
|.|..|||||||||.. ..||.|.|.|..|.||.|||| .|..|.| |.||||....|..|||||. . . |..|.|. ..|....|||||||..|
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdsp
TPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
...|.|||.|. ... . ||.||||||||||||.||..| .||....|..||... | .|.||..||||..||.|..|||||..
ellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1345-1624 | 1.2e-107 | 354.3 | In-house | 5-286 (293) | alignment | ||
Range on Protein: 1345-1624
Range on HMM: 5-286/293.0
PPIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLP
|| ...... ....||.. |.||.|||.. |.. . . ..|.||. |||| |...|||||| |..... .||||||||||.||. .. .||||||||
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlp
ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR-GTETCGLIQVTLLDTVELATYTVRTFALHKsgSSEKRELRQFQFMAWPDHGVPEYPTPIL
||. ||||||||... ..||.|.| || .|||..|||| . . | |.|||. . || ...|.....| ..|.|..||..|..|||||||| ....|
etvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktll
AFLRRVKACN--PLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT
.|.|.|. ...|.|||||||||||| || .| .|.....| .|||.| |. .|..||..||||.||.|||...|. .
dfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1333-1627 | 1.4e-106 | 351.6 | In-house | 12-303 (308) | alignment | ||
Range on Protein: 1333-1627
Range on HMM: 12-303/308.0
PSCPNTSSMRDHPPIPITDLADNIERlkANDGLKFSQEYESIDPGQQ-FTWENSNLEVNKPKNRYANVIAYDHSRVILtsidGvPGSDYINANYIDGY--
. . .|| . . .... ||. .|. |.| ....|.| . . .... ..|. ||.|||| ....||||||.| . .|||||||.|.|||
llfrdtsilvsslklsvldllkllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyss
RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR---GTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQF
......||||||||.|..|||||||||.. ..||.|.|.|..|.||.|||| |....| ..||||.. .|..|||||. | ..|..| |....|..
klprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhy
MAWPDHGVPEYPTPILAFLRRVKACNplDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCG
..|||||||..|...|.||..|. .. . ||.||||||||||||.||..| .||....|..||... | .|.||..||||..||.|...|||| . .
tnWpdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
H
l
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1359-1630 | 3.2e-104 | 343.4 | In-house | 21-297 (298) | alignment | ||
Range on Protein: 1359-1630
Range on HMM: 21-297/298.0
LKANDGLKFSQEYESIDPGQQ----FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVW
|... ....|.. .. ... ...| .. . || |||||..||.|.|||.|...|. |||||| ....|...||.||||.||.||. ||||||.
kkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvt
EQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAcNPL
|. .|.||.| |||. ..|. .||| .|.|| | |.|.|| . | | ..||.....|. ....||.||..|. |||.||||. | .|..||.|.| ..
eedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvra.sqq
DAG--PMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEV
.|| |..|.|||||||.| ||.||..|||.|.|..||.. | .| .| .||||.|||||.|| ||| ... .|.
qagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1650-1918 | 2.9e-101 | 333.7 | In-house | 21-287 (319) | alignment | ||
Range on Protein: 1650-1918
Range on HMM: 21-287/319.0
SVTAMELEFKLLASSKAHtsRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI
. | .| ||||| ... | ||. . || ||| ||..|. ||| |... ||||||||||||.|||......||||.||.. .||||||.||..| |
getllekefkllkeavnd..tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessi
IVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQ-SRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfGQDG
.|||||| | .. |...||| | .| ..|.. | .. .|| |..|. . . .|.. .||.|.||...||... . .|......|..|. |.|
vvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrek.tqsg
PITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD
||.||||||||||| ||.|...|||.. |||.|.|.||..|||||. |||...||...| | ||.. ..|
PivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1626-1914 | 3.4e-101 | 333.7 | In-house | 1-286 (288) | alignment | ||
Range on Protein: 1626-1914
Range on HMM: 1-286/288.0
GHTEVPARNLYAHIQKLGqvppGESVTAMELEFKLLASSKAHtSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYI
|.||.....|. ...|| ..| .. ||. | | ... . .|.||.|. ||| ..|.||. .||.|... |||||||||||..|||......|
gdteisveellklvlkll....angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfI
ATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA----RDGQSRTIRQFQFTDWPEQ
|||||| ...||||||.||.|...||||||| |.|||||.|||| . | | ..| . |. .. |..|...||. ||.|||...|..|.||..
atqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdh
GVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||| . | ..||. .|.| . ..||. |||||||||||.||.| ..||....||.||....||.||.||| ||||..||...|.|.||||
gvpdspellldflrlvrkala..sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1346-1621 | 1.9e-100 | 331.2 | In-house | 1-275 (278) | alignment | ||
Range on Protein: 1346-1621
Range on HMM: 1-275/278.0
PIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPET
||.. ||.. ...|..|. ....|.|... . .|.. ..|. ||.|||| ....||||||.|....|...||||||.|.|||......||||||||||
pisvkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpet
MGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPaRGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFL
..||||||||... |.||.|.|.|..||||.|||| .|..|.| ..||||.. .|..|||||. ... |..|.|. .......|||||||| ....| ||
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldfl
RRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
..|. ... . ||..|||||||||||.||... .||....|..||.. | .|.|| .|||..||.|..|||||
kavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1367-1629 | 2.4e-100 | 330.8 | In-house | 2-280 (284) | alignment | ||
Range on Protein: 1367-1629
Range on HMM: 2-280/284.0
FSQEYESIDPGQQF---TWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGV-PGSDYINANYIDGY-----RKQNAYIATQGPLPETMGDFWRMVWEQR
. .|.| . . . ... ..|. |. |||| ....||||||.|.|.|| ..||||||.|.||| ......||||||||.|..|||||||||.
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
TATVVMMTRLEEKSRVKCDQYWPARG-TETCGLIQVTLLDTVELATYTVRTFALHKSG-SSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNP--
. ..||.|.|.|..|.||.|||| | . |.| ..||||.. . .|||||. | . | ..| |....|....|||||||..|...|.||| |. ...
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
LDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEK---TVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTE
. ||.||||||||||||.||..| .||....|. .||... | .|.||..||||..||.|..|||||.. ...|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1649-1919 | 2.9e-100 | 330.9 | In-house | 39-304 (308) | alignment | ||
Range on Protein: 1649-1919
Range on HMM: 39-304/308.0
ESVTAMELEFKLLASSKAhTSRFISANLPCNKFKNRLVNIMPYELTRVCLqpirGvEGSDYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHN
. . .| ||. | | | . .|.||.|| ||| ..|.||. .||.| . |||||||||. ||| ......||||||| ...||||||.||.|
ldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqn
STIIVMLTKLREMGREKCHQYWPAE---RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeq
...||||||| |.|||||.|||| | | .| .|.| . |.... |..|....|. .||.|||...|..|.||..||| | ..||. .|.|.
vrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl..
fgQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH
..||| |||||||||||.||.| ..||....|| ||.|..||.||.||| ||||..||...|||.|||| .. .
..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklklt
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1360-1638 | 1.4e-99 | 328.4 | In-house | 8-292 (297) | alignment | ||
Range on Protein: 1360-1638
Range on HMM: 8-292/297.0
KANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIAYDHSRVILtsidGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRT
|... ....|.|...| . ..... ..|. |..|||| ....|||.||.| . .|||||||.|.|||. ....||||||||.|..|||||||||..
kllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnv
ATVVMMTRLEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVE--LATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL
..||.|.|.|. |.||.|||| .. |.| ..||||.. . |..||.||. . . |..|.|....|... ||||||||.|...|.|...|. ...|
tvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkl
--DAGPMVVHCSAGVGRTGCFIVIDAMLERMK---HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAH
. ||..|||||||||.|.||..| ||.... .|..|||. | .|.||. .|||..||.|..||||| .. | .|...|. .
lpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllklvll
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1338-1627 | 6.4e-99 | 326.4 | In-house | 5-293 (297) | alignment | ||
Range on Protein: 1338-1627
Range on HMM: 5-293/297.0
TSSMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQfTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGV-PGSDYINANYIDGYRK-QNAY
.... ...|||.. |. . ..|||. .. .|.|.. . .. ..|..||.|||| ....||||||.|...||| ..||||||.|.|||.. ....
rdallesipiplsvldlllllekansktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkf
IATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRvKCDQYWPARGTeTCGLIQVTLLDTVELATYTVRTFALHKsgSSEKRELRQFQFMAWPDHGVP
||||||||||..|||||||||.. ..||.|.|.|..| ||.|||| .|. |.| ..||||.. .|. |||||. . . ..| |....||.. |||||||
IatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvp
EYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGH
.... .| ||. |. .. . ||..|||||||||||.||... |||....|..||.. | .|.||...|||..||.|...|||| ...
pslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1361-1621 | 3.9e-97 | 320.2 | In-house | 8-270 (273) | alignment | ||
Range on Protein: 1361-1621
Range on HMM: 8-270/273.0
ANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIAYDHSRVILtsidGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA
... .. .|.| . . . ..|.. ..|. || |||| ....||||||.| | .|||||||.|.|||......||||||||.|..|||||||||..
llgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvr
TVVMMTRLEEKSRVKCDQYWPARG---TETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL--
..||.|.|.|..|.||.|||| | ..|.| ..||||.. . ..|||||. | ..|..|.|. ..|... |||||||......| |.. |. ..
viVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealp
DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
. ||.||||||||||||.||..| .|.....|..||.. | .|||| .||||..||.|..|||||
sngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1341-1621 | 6.4e-97 | 320.2 | In-house | 3-302 (307) | alignment | ||
Range on Protein: 1341-1621
Range on HMM: 3-302/307.0
MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQF---TWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGV-PGSDYINANYI--------DG
. ...|....| . .|.... .. .|.|.. . . | ... ..|..||.|||| ....|||.||.|.|.|| ..||||||.|. ||
lplslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldg
YRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE-TCGLIQVTLLDTVELATYTVRTFALHKS-GSSEKRELRQFQF
|......||||||||||. |||||.|||.. ..||.|.|.|. |.||.|||| |.| |.| ..||||.. .|. |||||. .. . |..| |....|..
ydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhy
MAWPDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
.|||||||... ..|.|...|.... . ||..|||||||||||.||... ||.....|.| ||.. | .|.|| .||...||.|..|||||
tgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1354-1623 | 1.5e-96 | 317.8 | In-house | 10-279 (288) | alignment | ||
Range on Protein: 1354-1623
Range on HMM: 10-279/288.0
DNIERLKANDGLKFSQEYESI-DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRM
... . .|.. ||.||.|. ... . . ..| ||..|||| |...||. || |. . ..|.|||||.||||..|...||||||||..|..|||..
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWel
VWEQRTATVVMMTRLEEKSRVKCDQYWPARGT-ETCGLIQVTLLDTVELATYTVRTFALHKSgsSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC
|.|..| |.||.| | |. . ||..|||. .. . | ..|||... || ...|.. |.|. ...|. |.|..||||||||| .|.|..|| ||
vyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekk..kteleitqyqylaWpdhgvPeskapllellrqvkva
NPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
|. |.||..||||||||||| ||..||.......|...|. | |. .| ||. .|||. ||.||.|.||. .
nqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1626-1921 | 2.3e-96 | 317.6 | In-house | 1-297 (298) | alignment | ||
Range on Protein: 1626-1921
Range on HMM: 1-297/298.0
GHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKA--HTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKA
| ||. |..| |..||| .| . ...| ..|||. | | . .. |. | || ||| .|.... .|| |. . . | |||||||||..|....|
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrna
YIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV
.||||.|| |..||||||..|.... |||||.|.|... |.|.||| |....| . |. ...... ..| |..||.... ..|..||..|| ||..||
fiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgv
PKTGEGFIDFIGQVHKTKEQFGqDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA
|.. . .|.. .|.....| | . |..|.|||||||.| || .. ||||.. | |||.||.||.||..||..||||.|| .| | ||.| ||. ..
penatsvldllrkvrasqqqag.nkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1654-1917 | 5.5e-96 | 316.5 | In-house | 2-277 (284) | alignment | ||
Range on Protein: 1654-1917
Range on HMM: 2-277/284.0
MELEFKLLASSKAHTS-RFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV-EGSDYINASFLDGY-----RQQKAYIATQGPLAESTEDFWRMLWEHN
.| ||. | | . . . . |.||.|. ||| ..|.||. .||.|... | |.|||||||..||| ...|..||||||| ...||||||.||.|
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
STIIVMLTKLREMGREKCHQYWPAER-SARYQYFVVDPMAEYNMPQYILREFKVTDAR-DGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQF
...|||||.| |.|||||.|||| | . .| | | . |.... |..|....|. .|.|||...|..|.||..||| . | ...|. .|.. |..
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
GQDGPITVHCSAGVGRTGVFITLSIVLERMRYEG---VVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSF
...||| |||||||||||.||.| ..||....|| .||....|| ||.||| ||||..||...|.|.|||| ..
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1652-1914 | 2.1e-95 | 314.9 | In-house | 18-276 (317) | alignment | ||
Range on Protein: 1652-1914
Range on HMM: 18-276/317.0
TAMELEFKLLASSKAHtsRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIV
||.. ||. | | | . . |.||.|| ||| ..|.||. .||.|.|. |...|||||||. ||.......||||||| ...||||||.||...|.||
talleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtviv
MLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPIT
|||.| |.|||||.|||| . . | |.| . |. .. ..||...|.| .|..|||...|..|.||..|||.. . ..||. .|.. | ...||.
mLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvl
VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|||||||||||.||.. ..||....|| ||....||.|| ||| .|||..||. .|.|.||||
VHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1346-1642 | 8.6e-95 | 312.4 | In-house | 3-302 (305) | alignment | ||
Range on Protein: 1346-1642
Range on HMM: 3-302/305.0
PIPITDLADNIERLKANDGLKFSQEYESIDPGqQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPET
.| . ||| |. .... .. ..|.|. . . . . |.|| |||..... .|..|.||| . .. ||||||.|.|||.....||..||||..|
iialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlknt
MGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE--TCGLIQVTLLDTVELATYTVRTFALHK-SGSSEKRELRQFQFMAWPDHGVPEYPTPIL
. ||||...| .. |.||.|.| | . || |||| . || | ..|.| .. . . |. | . . . ....|.| . |.|. |||||||...| .|
vadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsll
AFLRRVKACNPLDAG-PMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQK
...||. | | |..||||||||||| ||..| .|||.|.|..||... . .||.| .|||| |||||.|.|| | |||.|.. || |...|
slikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvnk
L
|
l
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1650-1914 | 1.3e-94 | 311.9 | In-house | 10-272 (273) | alignment | ||
Range on Protein: 1650-1914
Range on HMM: 10-272/273.0
SVTAMELEFKLLASSKAhTSRFISANLPCNKFKNRLVNIMPYELTRVCLqpirGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI
..| ...||.|| | | . |.||.|| ||| .|.||. .||.| | .||||||||..|||......||||||| ...||||||.||.|...
gltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrv
IVMLTKLREMGREKCHQYWPAER---SARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQ
|||||.| |.|||||.|||| | | .| | | . |.. . |..|....|. .|.|||...|..|.||..||| . | ...|| .|.|. |.. .
iVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealps
DGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.||. |||||||||||.||.| ..|.....|| ||....|| ||.||| ||||..||...|.|.||||
ngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1657-1913 | 1.6e-94 | 311.5 | In-house | 37-294 (330) | alignment | ||
Range on Protein: 1657-1913
Range on HMM: 37-294/330.0
EFKLLASSKAHtSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKL
||. | ... . . . |. || |||.|||.||. .|| |....||| ||||||||.|||.... .||.|||..|. ||||||.||..|. |||||.|
efnalPagpiq.atlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltel
REMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA----RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQdgPITV
.| .|||.|||| | . | | | . .| .|.| |.. |. .|| .||| || ||. ||| .. | .... .|.|...| .. ||.|
kerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag..pivv
HCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
|||||||||| ||.|. ||||.. |..||.|..|| ||.||| ||||. ||...|.. |||
hcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1650-1917 | 1.4e-93 | 308.9 | In-house | 30-292 (297) | alignment | ||
Range on Protein: 1650-1917
Range on HMM: 30-292/297.0
SVTAMELEFKLLASSKAHtsrFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV-EGSDYINASFLDGYRQ-QKAYIATQGPLAESTEDFWRMLWEHNS
| | ..|||. | | | . |.||.|| ||| ..|.||. .||.|.|..|| ..|||||||..|||.. ....||||||| |..||||||.||...
sktllllefeellslkpd...ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgv
TIIVMLTKLREMGReKCHQYWPAERSaRYQYFVVDPMAEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD
|.||||||| |.|| ||.|||| | . .| |.| . .. . |..|...||. .|.|||...||.|.||. ||| . | ...|. .|.. .. ...
tvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkg
GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSF
||. |||||||||||.||.. ..||....|| ||....||.|| ||| .|||..||. .|.|.||.| .
gpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
DSPc_SM00195 | 1367-1622 | 5.3e-93 | 306.5 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 1367-1622
Range on HMM: 2-261/263.0
FSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMT
...|.|... . . . .... . || |||| |.. |||.||.|..... .||||||||||.|..|...|||||||||.|. ||||||||... ..||.|
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
RLEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVELA-TYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVH
. ||. . |||.||| |.|| | |.|.| .. . ...||. | | | .|.|...|.|. .|||||||. ....|..|| || .. ||.|||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
|||||||||.|..|| .|.....||.||| |. .|.|| ||||..|| ||.||.||.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 1367-1622 | 5.3e-93 | 306.5 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 1367-1622
Range on HMM: 2-261/263.0
FSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMT
...|.|... . . . .... . || |||| |.. |||.||.|..... .||||||||||.|..|...|||||||||.|. ||||||||... ..||.|
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
RLEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVELA-TYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVH
. ||. . |||.||| |.|| | |.|.| .. . ...||. | | | .|.|...|.|. .|||||||. ....|..|| || .. ||.|||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
|||||||||.|..|| .|.....||.||| |. .|.|| ||||..|| ||.||.||.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1650-1914 | 6.4e-93 | 306.5 | In-house | 18-277 (278) | alignment | ||
Range on Protein: 1650-1914
Range on HMM: 18-277/278.0
SVTAMELEFKLLASSKAhtSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI
. |...|||. | | | . |.||.|| ||| ..|.||. .||.|... |...|||||||..|||......||||||| |..||||||.||...|.
lktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtt
IVMLTKLREMGREKCHQYWPaERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGP
|||||.| |.||.||.|||| . | .| |.| . |. .. |..| ..||. .||.|||........||..||| . . ..||. .|.. | ..||
ivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale..dsngp
ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
. |||||||||||.||.| ..||....|| ||....||.||.||| .|||..||. .|.|.||||
vlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1652-1917 | 1e-92 | 305.9 | In-house | 13-280 (297) | alignment | ||
Range on Protein: 1652-1917
Range on HMM: 13-280/297.0
TAMELEFKLLASSKAhTSRFISANLPCNKFKNRLVNIMPYELTRVCLqpirGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIV
. .. ||. | . .. . |.||.|. ||| .|.||. |||.| . |||||||||..|||......||||||| ...||||||.||.|.|.||
alllkefeellplll.lgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIv
MLTKLREMGREKCHQYWPAE--RSARYQYFVVDPMAEYN--MPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD
|||.| |.|||||.|||| | | | |.| . .. . |.||...||| ..|.|||...|..|.||. ||| . . ..||| .|.| ... ..
mltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsg
GPITVHCSAGVGRTGVFITLSIVLERMR---YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSF
||. |||||||||.|.||.. ..|.... .|| ||....||.||.||| .|||..||. .|.| ||.| ..
gpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1646-1914 | 2.5e-92 | 305.2 | In-house | 21-304 (307) | alignment | ||
Range on Protein: 1646-1914
Range on HMM: 21-304/307.0
PPGESVTAMELEFKLLASSKAH-TSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV-EGSDYINASFL--------DGYRQQKAYIATQGPLAEST
. ...| .. ||. | | . . . .|.||.|| ||| ..|.||. |||.|... | |.|||||||. |||......||||||| |.
llldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetv
EDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA-RYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDF
|||||||||...|.|||||.| |.|||||.|||| |.. | |.| . |. .. |..| ..||| .|.|||...|..|.||..|||.. | ..||
edFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldf
IGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
| .|.| |. ...||. |||||||||||.||.. ..|.....||. ||....||.|| ||| .||...||. .|.|.||.|
ieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1389-1625 | 4.9e-92 | 302.6 | In-house | 8-244 (250) | alignment | ||
Range on Protein: 1389-1625
Range on HMM: 8-244/250.0
VNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVkCDQYWPARGTETCG
|| |||||..||.|.|||.| . .| |||||| ...||....|.|||||||..|. ||||||.|. ..|.||.| |.|. .. . ||||. ..|. |
qnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyG
LIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL-DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEK
..|.||.. | | ||.|.. | | ...| .||..|..||| ||||. | .|..|..|.| .. ...|..|.|||||||.|.||.|||.|||.|.||
dvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkek
TVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATC
.||.. . .| .| .|....||||..|..|.| ..
vvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1366-1642 | 5.2e-92 | 303.5 | In-house | 35-310 (319) | alignment | ||
Range on Protein: 1366-1642
Range on HMM: 35-310/319.0
KFSQEYESI--DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM
|. |. . . . . . .||. || |||. |..|.|...| | ..|. .|||||| ...||.... |||.||||..|. |||||.||....|.|.
klevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivl
MTrleeksRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHK-SGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD--AGPMV
.| . || |||| .. .. . .| . | | |.|| . | . . ..|...|| |. |||.|||.||.... ....|. . ..|
lt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhraniv
VHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKL
||||||||||| .||.|..|.|||.|| ||.| | .| ||| .|| || ||. |||| ||..| .. |....|
vhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleel
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1344-1638 | 8e-92 | 302.5 | In-house | 3-293 (315) | alignment | ||
Range on Protein: 1344-1638
Range on HMM: 3-293/315.0
HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLP
| |||. .| . . ||. | |.|||| || . . .. || |||| |.||||.||| | .. |.|||.|||.|||| |.. |||.|||..
hqpipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnv
ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARgTETCGLIQVTLLDTVELATYTVRTFalHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILA
....||||.|.|. ...||.| | |. . |...||| . . | | ||. . |||||. .. ||. |... .||| |||.| .|..
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdmgvpkytiplmn
FLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVpARNLYAH
. |.|| . ..|..|||||||||||| || .||.|.... |. .|.| .| .|..| |||. .|| ||..||||. || | . |..|| .
lirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsi.aqdlylq
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1381-1621 | 1.4e-90 | 298.5 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 1381-1621
Range on HMM: 2-244/249.0
TWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP
... ..|..||.|||| ....||||||.|....|...||||||.|||||. ....||||||||||..|||||.||.. ..||.|.|.|. |.||.||||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTGCFIVIDA
.|. ..| ..||||.. ... |||||. |.... .|.|. ...|. |||||||... ..|.|...|. .. . ||..|||||||||||.||...
lggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
MLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
|||....|..||.. | .||||...||...||.|..|||||
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1382-1642 | 2.2e-90 | 298.0 | In-house | 17-274 (284) | alignment | ||
Range on Protein: 1382-1642
Range on HMM: 17-274/284.0
WENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTrleeksRVKCDQYWPA
. .||. || |||. ...|.|...| | ..|. .|||||| .| ||.... ||||||||..|. |||||.||....|.|..| . || ||||
qtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywpl
RGTETCGLIQVTLLDTVELATYTVRTFALHK-SGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD--AGPMVVHCSAGVGRTGCFIVIDA
.. .. . .| . | . |.|| . | . . ..|..||| |. |||.|||.||.........|. . ..|||||||||||| .||.|.
kivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldv
MLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKL
.|.|||.|| ||.| | .| ||| .|| || ||. |||| ||..| .. |....|
lldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleel
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1672-1914 | 7.3e-90 | 296.1 | In-house | 4-246 (249) | alignment | ||
Range on Protein: 1672-1914
Range on HMM: 4-246/249.0
ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAE
|.||.|| ||| ..|.||. .||.|....|...|||||||..|||......||||||| |..|||||||||...|.|||||.| |.|||||.|||| .
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplg
RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVL
| | |.| . .. .. |..|....|. ||.|||....|.||||..|||.. | ..||| .|.| |. ...||. |||||||||||.||.. ..|
gsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylml
ERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|....|. ||....||.||.||| .||...||. .|.|.||.|
eqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
DSPc_SM00195 | 1657-1914 | 4.4e-89 | 293.7 | In-house | 5-262 (263) | alignment | |||
Range on Protein: 1657-1914
Range on HMM: 5-262/263.0
EFKLLASSKAHTsRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKL
||. | .|. .. .. .|. . || ||| ||.||. ||| |... . ||||||||....|....|.|||||||| . |||||| ||....||||||.
efekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmltee
REMGREKCHQYWPAE--RSARYQYFVVDPMAEYNMP-QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFgqDGPITVH
| |.|||..||| | .. ..... | . . ... ..|||....| . ..|...|.|...||..|||.. . ..... .|.|.|.. .||| ||
eengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpivVh
CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|||||||||.|.|..|.|.... | ||.|..|| ||.||| ||||..||. .|.|.|||.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 1657-1914 | 4.4e-89 | 293.7 | In-house | 5-262 (263) | alignment | |||
Range on Protein: 1657-1914
Range on HMM: 5-262/263.0
EFKLLASSKAHTsRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKL
||. | .|. .. .. .|. . || ||| ||.||. ||| |... . ||||||||....|....|.|||||||| . |||||| ||....||||||.
efekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmltee
REMGREKCHQYWPAE--RSARYQYFVVDPMAEYNMP-QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFgqDGPITVH
| |.|||..||| | .. ..... | . . ... ..|||....| . ..|...|.|...||..|||.. . ..... .|.|.|.. .||| ||
eengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpivVh
CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|||||||||.|.|..|.|.... | ||.|..|| ||.||| ||||..||. .|.|.|||.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1390-1621 | 6.3e-89 | 292.8 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 1390-1621
Range on HMM: 1-235/235.0
NKPKNRYANVIAYDHSRVILtsiDGVPG-SDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP--ARGTET
|| |||| ....||..|| | .| .| ||||||||..||......|||||||..|..|||||||.... ..||.|.||||.|.||.|||| ....|
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
CGLIQVTLL-DTV-ELATYTVRTFALHKSGSS-EKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM
.| |.|.| .. . . ||.|.. |.|.... ||||..|... .|||||||| |...| ..|.|. . . ||.||||||||||||.|...|..||..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
..|..||.. | .|.||. |||...||.|...|.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1390-1621 | 6.3e-89 | 292.8 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 1390-1621
Range on HMM: 1-235/235.0
NKPKNRYANVIAYDHSRVILtsiDGVPG-SDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP--ARGTET
|| |||| ....||..|| | .| .| ||||||||..||......|||||||..|..|||||||.... ..||.|.||||.|.||.|||| ....|
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
CGLIQVTLL-DTV-ELATYTVRTFALHKSGSS-EKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM
.| |.|.| .. . . ||.|.. |.|.... ||||..|... .|||||||| |...| ..|.|. . . ||.||||||||||||.|...|..||..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
..|..||.. | .|.||. |||...||.|...|.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1345-1642 | 9.3e-89 | 292.6 | In-house | 2-305 (307) | alignment | ||
Range on Protein: 1345-1642
Range on HMM: 2-305/307.0
PPIPITDLADNIERLKANDGLKFSQEYESID-PGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLP
..|.| ||..... | . . .|||.. . . ..|. . |. |||| ...|.|. ||.|. | | ||||||..| ||.... .|| |.|.
gaiaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPve
ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSG-----SSEKRELRQFQFMAWPDHGVPEYP
.|.||||||..|| ..||.. |.||.| ||..||| . | | |.| .. . |. |.. . | . ..|.. |.....|.| ||| .
atigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPeva
TPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAH
. .| ....|. . |. .|.||||||||||.| |. .| .|...| |..|||. | .||||| .|| .||||.. |||. . |.|.. ..| .
rgllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddleda
IQKL
|..|
ierl
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1353-1622 | 2.5e-88 | 290.9 | In-house | 3-275 (281) | alignment | ||
Range on Protein: 1353-1622
Range on HMM: 3-275/281.0
ADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWR
....|..|| | .|||.. |.. | . |. . |. |||| |..|||..|| .| . .||||||...||.....|||||||.|... .||.
rkhlkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWq
MVWEQRTATVVMMTRLEEKSRVKCDQYWPARG-TETCGLIQVTLLDTVELATYTVRTFALhKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKA
|||||. ..||.|| |....|| .||| . . | ..|. . . | ||| |.| | . |.|.||..|....||||||||. .. .| | . |.
mvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlk
CNPLDA-GPMVVHCSAGVGRTGCFIVIDAMLERMKHE-KTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
.. . |.|.||||||||||..| .| .......| ...|. |. .| .||.|||| || |.. |.|.|
ltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavlda
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1383-1621 | 2.6e-88 | 290.8 | In-house | 2-241 (245) | alignment | ||
Range on Protein: 1383-1621
Range on HMM: 2-241/245.0
ENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR
. ..|..||.|||| ....|||.||.|....| ..||||||.|.|||| . .|||||||||| .|||||.||.. |.||.|..||..||||.|||| .
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
GTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCSAGVGRTGCFIVIDAMLE
.. |.| ..||||.. |..|||||. ... |..|.|| ...... |||||||... .| ||..|. . . ||..|||||||||||.||... |||
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
....|..|... | .|||| .|||..||.|..|||||
qlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1369-1624 | 2.8e-88 | 291.1 | In-house | 12-273 (278) | alignment | ||
Range on Protein: 1369-1624
Range on HMM: 12-273/278.0
QEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVIltsidgvpgsDYINANYIDGYrkQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLE
. .. . .|. ........ |..|||| ....||||||. |||||.||||| ....||||||||.|. |||||.||... ..||.|.|.
efefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelv
EKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKS----GSSEKRELRQFQFMAWPDHGVPEYP--TPILAFLRRVKACNPL--------
|..|.||.|||| .|..|.| ..||||.. .| .||.||. .. . |.|........ |||||||..| ...| .|....... |
elgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllss
-----DAGPMVVHCSAGVGRTGCFIVIDAMLERMkhEKTVDIYGHVTCMRSQRNY-MVQTEDQYVFIHEALLEAAT
. ||..|||||||||||...... |||.. |..||.. |. .||||.. .||...||.|..|.|||
lllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1657-1914 | 1.9e-87 | 288.0 | In-house | 30-285 (293) | alignment | ||
Range on Protein: 1657-1914
Range on HMM: 30-285/293.0
EFKLLASSKaHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKL
|.. | . . .. .|.|..|. ||| ||.||. .|| |..... .|||||||....||.... .||||||| |...|||||.||..|.||||||.|
eyeelkavg.kdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltql
REMGREKCHQYWPAE-RSARYQYFVVDPMAEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCS
| |..||..||||. .. | |. .|| .. ....||.|.. . ..|..||..|| ||. |||.. . ..||. .|....|. ...||.||||
vekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCs
AGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|||||||.||.| .|.... | .||.| .| ||..| .||||.|| ... |..|
aGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldll
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1367-1623 | 2.2e-87 | 287.9 | In-house | 18-290 (297) | alignment | ||
Range on Protein: 1367-1623
Range on HMM: 18-290/297.0
FSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMT
|.||. | . | ..|.| .| ||||..|. ||..|| |...|. . |||||||..|||....|.|||||||..|. |||||||||.. ..||.|
lskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmtt
RLEEKSRVKCDQYWP--ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC------------
|..|. |.|| |||| .. | ..|. ....| |.||.. .... .|.|.. |||..|||.|||. . .| .|. |.
rvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdew
-NPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
... |.|||||||.|||| || .| |.|.... |||. | .|.|| ...||..||.| . |.|| |
kghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1651-1918 | 6.9e-86 | 283.1 | In-house | 21-287 (305) | alignment | ||
Range on Protein: 1651-1918
Range on HMM: 21-287/305.0
VTAMELEFKLLASSkaHTSRFISANlPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTII
...| ..|.|.. ..| .. . || ||||..|.... |. |.. .. |||||||..|||...|.||..|||| . .||||...| . |
dkgleaqykslyee..eesidvgkk.eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvsti
VMLTKLREMGREKCHQYWPAERSA--RYQYFVVDPMAEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfGQD
||||||.| |..||.|||| . . ... |.| | ....|| |..|.. | .|||. |.|.||||..|||.. ....| .|.|.... ...
vmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk.dkg
GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD
|..||||||||||||||...| |||.. |.|||.|. .|.||..|. |||| |||. .. | |.. ..|
vpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgd
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1654-1915 | 1.2e-85 | 282.5 | In-house | 11-273 (278) | alignment | ||
Range on Protein: 1654-1915
Range on HMM: 11-273/278.0
MELEFKLLASSKahtSRFISANLPCNKFKNRLVNIMPYELTRVClqpirgvegsDYINASFLDGYrqQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.| ||.|| .. |.. |....|. ||| ..|.||. .||. ||||||..||| .|..||||||| . ..||||||||...|.||||
lefefllllgip...seitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivml
TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA----RDGQSRTIRQFQFTDWPEQGVPKTG--EGFIDFIGQVHKTKE-----
|.| |.|||||.|||| . | .| |.| . |.... |.|| ..||. |..||........ ||. ||| . |.... .... .
telvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllasl
------QFGQDGPITVHCSAGVGRTGVFITLSIVLERMryEGVVDMFQTVKTLRTQRPA-MVQTEDQYQLCYRAALEYLG
.....||. |||||||||||... . ..||.. ||.||....||.||.||| .||...||. .|...||.|
llsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1674-1914 | 1.8e-84 | 278.2 | In-house | 4-243 (245) | alignment | ||
Range on Protein: 1674-1914
Range on HMM: 4-243/245.0
ANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERS
|.||.|| ||| ..|.||. |||.|.|. | ..|||||||. ||||. . .|||||||.|..|||||||||...|.|||||.. |.||.||.|||| . |
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges
ARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVLER
.| |.| . |.... |..|...||. .|..||.........||..||| . | ..||. |.| .. ...||. |||||||||||.||.. ..||.
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae.dsngpvlVHCsaGvgRtGtfiaaylmleq
MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
...|. |.....|| || ||| .|||..||. .|.|.||.|
lekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1652-1916 | 1.9e-84 | 278.9 | In-house | 19-289 (563) | alignment | ||
Range on Protein: 1652-1916
Range on HMM: 19-289/563.0
TAMELEFK-LLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGS-DYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI
. .. ||. | ..... ... |.|| ||| .||..|. .|| |.|. |.... |||||...|||...||.|||||||.. ..|||||.||.|..|
igfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvai
IVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAE-----YNMPQYILREFKVTDARD-GQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQ
|||.|.| | ||.||..|||.. | .|. . | ..| |.. . .....|. . .. . ...||...|.||..|||. . |. . .....
ivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaanka
fgQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGS
. |||.|||||||||||..| |. .|.... | .|..|...|..|.||. .||||.||. . | || . |
..eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1665-1914 | 7e-84 | 276.4 | In-house | 28-290 (297) | alignment | ||
Range on Protein: 1665-1914
Range on HMM: 28-290/297.0
KAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKC
.. . .| ..|..| ||| ... |. ||| |. . . | ||||||.|.|||.|.||.||||||| . ..|||||.||.. .||| |.. |.|| ||
epveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkc
HQYWP--AERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFG-----------QDGPIT
|||| | ||.. . | . .. .| | ..........||.. |||. ||. |||.... ..|.. .| ... .. .. ||
gqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPiv
VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||||||.|||| |||| | |.|.. .|.||...|||.||||| ..||..||..|| | |||
vhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1675-1921 | 1.3e-83 | 275.1 | In-house | 5-249 (250) | alignment | ||
Range on Protein: 1675-1921
Range on HMM: 5-249/250.0
NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREkCHQYWPAERSA
. | || ||| .|.... .|| |.. .| . |||||||||.||...||.||||||| ...||||||..|..|. |||||.|.|.... .|||||.|..
kkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekae
RYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVLERM
.| |... . .. |. |..|.. |. ..|..||..|. ||..|||.. . .... .|.....| ...|. |.|||||||.| ||... ||||.
kyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqq.agnaPvivqCsaGvgrsGafiaidavlerl
RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA
. | |||.|. .|.||..|| .|....|| .|...|..| |.. ||
kkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedya
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1365-1620 | 1.8e-83 | 275.0 | In-house | 26-294 (306) | alignment | ||
Range on Protein: 1365-1620
Range on HMM: 26-294/306.0
LKFSQEYESI---DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTsIDGVPGSDYINANYIDGY--RKQNAYIATQGPLPETMGDFWRMVWEQRTA
|..|.|.. . .... .... || |||| |.. .||.||||. ..||||||||||||.. ....|||||| |..|. |||||||.. .
agfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensr
TVVMMTRLEEKSRVKCDQYWPARGT-ETCGLIQVTLLDTVELATYTVRTFAL-HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC----NP
.||.|. |... || .|||. . |. | |.|| .. .||.|..|.. . .|. ..|.||..|..| .|||||||. | .|.||. |.. .
vivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeelee
LDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHE---KTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALL
.|||.|||||||.|||| |||||..|. .... .||. | .|.||. .||||.|| |...|.
aeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1649-1913 | 1.3e-82 | 272.7 | In-house | 31-291 (319) | alignment | ||
Range on Protein: 1649-1913
Range on HMM: 31-291/319.0
ESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNST
. .| .| ||. .. . . |||. || |||..||.... ..| |... |.|.||||||||..||.... |||.|||| .. .|||||.||.|..
ddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncs
IIVMLTklremgREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD
||.|| ..|| |||| . ... | |. . . .|..|...... .. . | |.|| | ||..|||. . .. .. .|.. ... .
tivllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhr
GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE-Y
.| ||||||||||||.|.| ..|.||. | ||....|. || ||. .|| ||...| | || .
anivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1679-1912 | 8e-82 | 269.5 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 1679-1912
Range on HMM: 1-235/235.0
NKFKNRLVNIMPYELTRVCLqpiRGVEG-SDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP--AERSAR
|| ||| .|.||. ||| | .| || ||||||....||...|..||||||| .. ||||||.|......|||||.| |.|||||.|||| |.| .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YQYFVVDPM-AEY-NMPQYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqFGQDGPITVHCSAGVGRTGVFITLSIVLE
|. . | . | .. .|.||...... . ..|...|...|.||..|||.. ....|.| .|.|.| ..||..|||||||||||.|..|.|.||
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGvgRtgtfvaldille
RMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
... |. ||..|.||.||.||| |||...||. .|.| ||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1679-1912 | 8e-82 | 269.5 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 1679-1912
Range on HMM: 1-235/235.0
NKFKNRLVNIMPYELTRVCLqpiRGVEG-SDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP--AERSAR
|| ||| .|.||. ||| | .| || ||||||....||...|..||||||| .. ||||||.|......|||||.| |.|||||.|||| |.| .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YQYFVVDPM-AEY-NMPQYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqFGQDGPITVHCSAGVGRTGVFITLSIVLE
|. . | . | .. .|.||...... . ..|...|...|.||..|||.. ....|.| .|.|.| ..||..|||||||||||.|..|.|.||
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGvgRtgtfvaldille
RMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
... |. ||..|.||.||.||| |||...||. .|.| ||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1678-1912 | 1.9e-81 | 268.3 | In-house | 42-275 (314) | alignment | ||
Range on Protein: 1678-1912
Range on HMM: 42-275/314.0
CNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSArYQ
|. ||| .|..|. .|| |..| | ||||||...|.|.. .|.|.||||| | ..||||.....|.. |||||.| | || || .||| . . |.
enreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.yg
YFVVDPMAEYNMPQYILREFKVTDARDG--QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfgQDGPITVHCSAGVGRTGVFITLSIVLERMR
. | . ... | |.|. . | . |..|||||. ||. .||. .|..... .|.|..|. ..|.| |||||| ||||.||...|||. ..
dikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..eaGrivvhCsaGaGrtGtfiaidivldmie
YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
|||||.|..|||||.... ||.||.||...| ..||
regvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1650-1911 | 2.1e-81 | 268.1 | In-house | 19-276 (288) | alignment | ||
Range on Protein: 1650-1911
Range on HMM: 19-276/288.0
SVTAMELEFKLLASSKAHTSRfISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI
. | .. |.. ||. . . | ..|. |. ||| ||.||. .|| |. ..|.||||||..||....|.|||||||||.. .|||.. .|....
nrtgfseeynsLaalektksv.tagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktst
IVMLTKLREMGREKCHQYWPAERS-ARYQYFVVDPMAEYNMPQYILREFKVTdaRDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFgqDG
|||||.| | |..||..|||.. .| . | . . .. ...||.. . .... ..| |.|.. ||..|||. . ..... ||. .... |
ivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad..tg
PITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAAL
||.|||||||||||.||.| ...... | ..|.. ||. || ||. .|||. ||. .|.. |
piivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1378-1622 | 4.9e-81 | 266.8 | In-house | 28-276 (290) | alignment | ||
Range on Protein: 1378-1622
Range on HMM: 28-276/290.0
QQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQ
.... |... |.|. |||| ... ||.||| |. |....||||||||.| | .. .|||.|||||.|. |||||.||... |||. |. | . ||..
kvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
YWPARGTETC--GLIQVTLLDTVELA-TYTVRTFALHKSgsSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFI
||| .| |.. | ..||| . . ...||...... .|.|...||...||||||||. ....|.... |. . .. |.|||||||||||| |
YWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtii
VIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
.|| . | .|.||. .|.. |. .| ||. .|||..||.....|..|
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1654-1914 | 6.5e-81 | 266.8 | In-house | 24-286 (307) | alignment | ||
Range on Protein: 1654-1914
Range on HMM: 24-286/307.0
MELEFKLLASSKAHTSRfISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.. |.. | ... . | .. |..||| .|.... ||| |..| | | ||||||||. ||...| .|| |.|. . .|||||..| ..|.||||
lakeyekLeareidkst.kvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivml
TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARD-----GQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFgqDG
..| |. |.||..||| | .|. .|... | ....|| ||..|. . .|| . |...| |.. ||.. .| ...| ||.. ... .
snlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln..rs
PITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||.|||||||||.|.|..|...|.... | ||.|.||| || ||. .|| .||. .||| |.|
PivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1382-1621 | 8e-81 | 266.4 | In-house | 2-240 (243) | alignment | ||
Range on Protein: 1382-1621
Range on HMM: 2-240/243.0
WENSNLEVNKPKNRYANVIAYDHSRVILtsidgvPGSDYINANYIDGYRKqnaYIATQGPLPETMGD----FWRMVWEQRTATVVMMTRLEEKSRVKCDQ
. ..|..|..|||| ....||||||.| .||||||||.|..... .|||||||||| | ||||.||... ..||.|.|.|..|.||.|
fsiallpenlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq
YWParGTETCGLIQVTLLDTVELATYTVRTFALHKSG-SSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC--------NPLDAGPMVVHCSAGVG
||| |..|.| ..||||.. .|. |||||. | . . ..|. .......|||||||. |...|.||. |... . . ||..||||||||
ywp..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTGCFIVIDAMLERMkhekTVDIYGHVTCMRSQRNY-MVQTEDQYVFIHEALLE
|||..|... ||... .||.. | .|.||.. .|||..||.|..|||||
RtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1346-1659 | 1.1e-80 | 265.8 | In-house | 2-313 (315) | alignment | ||
Range on Protein: 1346-1659
Range on HMM: 2-313/315.0
PIPITDLADNIErlKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPET
|||.... .. | ||.|. . . . . ..| .|||| |.. .|..||.| || | |||||| || .. ...||||.||||. .
pipvaqfpafvn..knrhtalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkas
MGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE--TCGLIQVTLLDTVELATYTVRTFALHKSgsSEKRELRQFQFMAWPDHGVPEYPTPILA
. ||||||......|.||.| ..| ..|| |||| | .. | |.|.||.. . ..| . . || |.| . |||| |||.||.. . .|
vddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrks..eesrtvtqfqftewPdkGvdkqtssllk
FLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG
... ||| | . ...||||||||||| .| || .....|....||.. |. .|..| |.||||..| ||..|.|| | .. .. |.| |
likevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqdlh
QVPPGESVTAMELEFK
|. . | ||.
tsvdgsgrskmtkefe
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1656-1913 | 2.4e-80 | 265.1 | In-house | 2-255 (284) | alignment | ||
Range on Protein: 1656-1913
Range on HMM: 2-255/284.0
LEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTk
||. .. . .. |||. || |||...|.... ..| |... |.|.||||||||. ||.... |||||||| .. .|||||.||.|.. ||.||
vefrracklgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.
lremgREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHC
..|| |||| . ... | |. . . .|..|...... .. . |.|||| | ||..|||. . .. .. .|.. ... . .| |||
.....kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhc
SAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE-Y
|||||||||.|.| ..|.||. | ||....|. || ||. .|| ||...| | || .
sagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1365-1663 | 1.3e-79 | 262.7 | In-house | 18-316 (515) | alignment | ||
Range on Protein: 1365-1663
Range on HMM: 18-316/515.0
LKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM
||.|. . . . .. |.| .|||| |.. || .||.| |. | |||.|| || .. ..||||.|||.. .. ||||.|......|..|.
tlfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamv
TRLEEKSRVKCDQYWPARGTET--CGLIQVTLLDTVELATYTVRTFALHKSGSseKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVH
|.|.| ..|| .||| . ... | |.| |. . . . |.. . |. | . ||.| |||.|||. . .| ... ||| . . |...|
tklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliih
CSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLA
||||||||| .| || .. ..| ..||.. || .| .| |.|||..|| ||..|.|| | .| . |.| | |. . | ||. |
csaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrskmtkefqtlk
S
|
s
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1652-1914 | 3.4e-79 | 261.0 | In-house | 26-297 (306) | alignment | ||
Range on Protein: 1652-1914
Range on HMM: 26-297/306.0
TAMELEFKLLASS-KAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQpIRGVEGSDYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHNST
. .| ||. | . . .. .. | || ||| ||.|.. ||| |. .| |||||||..... ..|.|||||| | . .|||||.|. ||.
agfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensr
IIVMLTKLREMGREKCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVT-DARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFG-
.|||.|| | |.||| .|||.| . . | | ..| .. .|||||..|. .....|...|..|..||..|||| . ..||. .|.. .|..
vivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeelee
-QDGPITVHCSAGVGRTGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
. ||| ||||||.|||| || . |.|. ....|. .|. ..||..|.|| .||||.||.. |.| .|.
aeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyi
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1347-1658 | 6.6e-79 | 260.4 | In-house | 5-323 (325) | alignment | ||
Range on Protein: 1347-1658
Range on HMM: 5-323/325.0
IPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETM
| . .| ...|. ||.| |..|.. . . . . . . . || |||. ||.|.|.|||.| . . | ||||||.|. ..|.. ..|.| ||..|.
iavvnlvehvekkkaqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltati
GDFWRMVWEQRtATVVMMTRLEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAF
.|.||.| . | ..||... .. .| .||| . . | | ..| | |.. | | . . . | | ..|||...|.| ||...|. ....
ndlWrlvldWr.csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisi
LRRVKAC------NPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAH
|. ||| | ..|..||||||||||| || . ..|... .| |||.| | .| .| ||.| |||..|.||| || .| |.|| .. |.
lqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeak
IQKLGQVPPGESVTAMELEF
. | . | .| ||
lsslqernpltqklniekef
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1388-1622 | 1.7e-78 | 258.1 | In-house | 5-239 (239) | alignment | ||
Range on Protein: 1388-1622
Range on HMM: 5-239/239.0
EVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTET
||| ||||||...||||||.| . | ||||||.|. | .||||||| . . ||||||.|..| . .||.| | | . || |||| ..
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsky
CGLiQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHE
| | .||| | .| | .||| . . | .|.| . |..| |||.|||.| | .| . |.. . | | |.||||||||||.|.|||||| . |..
cnl.rvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkq
KTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
|||||. .| ..| .| .|||| .|||||| |.|||
ktvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1386-1621 | 4.4e-78 | 256.7 | In-house | 4-239 (239) | alignment | ||
Range on Protein: 1386-1621
Range on HMM: 4-239/239.0
NLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT
. ||| ||||||...||||||.| . | ||||||.|. | .||||||| . . ||||||.|..| . .||.| | | . || |||| .
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts
ETCGLiQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMK
. | | .||| | .| | .||| . . | .|.| . |..| |||.|||.| | .| . |.. . | | |.||||||||||.|.|||||| . |
kycnl.rvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqak
HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
..|||||. .| ..| .| .|||| .|||||| |.||
kqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1673-1914 | 1e-77 | 255.9 | In-house | 34-277 (290) | alignment | ||
Range on Protein: 1673-1914
Range on HMM: 34-277/290.0
SANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAE-
... . |. ||| .|.||. .|| |. |...||||||||.|. | ....|||.||||.. .|||||.||.| .|.||. .. |.|. ||..||| |
agekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeeg
-RSARYQYFVVDPMAEYNMP-QYILREFKVTDArdGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRTGVFITLSI
.. ... | |. ..| .. ....| .||. ..||...||..|.||..|||.. . ...| .|....| .| |. |||||||||||. |.. .
eeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..sedaPlvvhCsaGvGrtGtiiaidy
VLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
| | .. | . .|.|. | .||.||.|.|||..||.| |.| .|..
vrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1655-1920 | 3.7e-77 | 254.0 | In-house | 23-289 (290) | alignment | ||
Range on Protein: 1655-1920
Range on HMM: 23-289/290.0
ELEFKLLASSKAHTSrFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEG--SDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVM
. .|| | |.. . . .. . || .|| ||..|. |. |.|| | . .||||....||...|.|||||||. . |||...|....|||||
rnqfkmldsgeseht.vtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivm
LTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARD-GQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqDGPIT
||. |.|..||.||||.. ...|..| . . | .. .|| |...|.. . |..... |.|.| |...| . .. . | .. ||. . | ...|
ltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrg.ntsiv
VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHY
||||..|||..||... . ..... |||.|.|| .|..|.|.| .|||..|||. .. |.|| ||. |
vHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1383-1622 | 8e-77 | 253.2 | In-house | 30-268 (273) | alignment | ||
Range on Protein: 1383-1622
Range on HMM: 30-268/273.0
ENSNLEVNKPKNRYANVIAYDHSRVILTSIDGvpgsdYINANYIDGYRKQ--NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP
| .. . || |||| ||. ||..||.| . | ||||..| . |||.|||||||. |||.|||||.. ..|.| || .|||..|||
evgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywP
ARGTETCG---LIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPlDAGPMVVHCSAGVGRTGCFIVID
. .. ..|.||....| ...||..|...| |.| ||. ...|..||||||| ....| |...|. . ||||.|||||||.||.| .|.||
esknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitid
AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
..|. ....| .|. | ..| ||. .|||.|||.|...|.||.
vvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1673-1914 | 1.9e-76 | 252.1 | In-house | 4-242 (243) | alignment | ||
Range on Protein: 1673-1914
Range on HMM: 4-242/243.0
SANLPCNKFKNRLVNIMPYELTRVCLqpirgvEGSDYINASFLDGYRQqkaYIATQGPLAESTED----FWRMLWEHNSTIIVMLTKLREMGREKCHQYW
|.||.|. ||| .|.||. .||.| ||||||||.. ..... .||||||| |..|| |||||||...|.|||||.| |.|||||.|||
iallpenlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PaeRSARYQYFVVDPMAEYNMPQYILREFKVTDAR-DGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQ------FGQDGPITVHCSAGVGRT
| . .| |.| . |.....|..|..... |...|........ ||..||| . | ..||. .|.. |. ..||. ||||||||||
p..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GVFITLSIVLERMryeGvVDMFQTVKTLRTQRPA-MVQTEDQYQLCYRAALEYL
|..|.. ..|... | ||....||.||.||| .|||..||. .|.|.||.|
Gtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1673-1914 | 2.7e-75 | 248.1 | In-house | 35-276 (281) | alignment | ||
Range on Protein: 1673-1914
Range on HMM: 35-276/281.0
SANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER
... . |. ||| .||. |. ||| ..| . .|||||.|..||...|.|||||||. .| ..||.|.||.. ..|||.|. | |. |||.||| ..
askadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddn
-SARYQYFVVDPMAEYNMPQYILREFKVtDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQdGPITVHCSAGVGRTGVFITLSIVL
. .| ..| .|| . ..|| |.||. ....|..|...|...| ||..|||.| . ...| .|.|..|. . |. .||||||||||..|.| ..
selkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktk.aplvihCsaGvGrtGtyialDrlv
ERMR-YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
... . .|. ..|. || .| |||| ||. |.| |..|
kaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1342-1633 | 8e-75 | 246.7 | In-house | 5-294 (297) | alignment | ||
Range on Protein: 1342-1633
Range on HMM: 5-294/297.0
RDHPPIPITDLADNIERLKANDglKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKqnAYIATQGP
.. |||..|.| ... . | ||.|. . . .. .. || .|.||.|.. || |||.| ... | |||.|| .. |... .|.|| |
kerrpiplsdfatlvqknrhtd..vfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmP
LPETMGDFWRMVWEQRTATVVMMTRLEEKSRvKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPE--YPT
..|. |||.||......|.||.. ..|. . || .||. .|. | | . |.|| . | . |.. . |. . .| ..|.||. |||. |.. .
mkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsas
PILAFLRRVKACNPLDAG-PMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPAR
.| .. |. | |..|||.||||||| .. || .. ..|.||.|||.| |. .| .| |.|||..|| |...|.||| . .|...|
sllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqas
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1380-1621 | 4.7e-74 | 243.9 | In-house | 18-266 (274) | alignment | ||
Range on Protein: 1380-1621
Range on HMM: 18-266/274.0
FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPG-SDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQ
|. |. .. .. |||| ... ..|||.|.| .. |.||||||| ||.. ..||.|||||||.|. |||||...... .||.|.|.|. . || .
fdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCav
YWPARG----TETCGLIQVTLLDTVELATYTVRTFALHKSGSseKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN---PLDAGPMVVHCSAGVGRT
|.| . .|. | .... ..|| |.||.. |... . .|.. . . .|||| .|. ....| ... |. . ..|.|||||||.|||
yfPdaedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrt
GCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
|||| |. . ....|..||. . |. .| .| ||||..|| .||.|| .
GcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1347-1625 | 9.4e-74 | 242.9 | In-house | 2-285 (290) | alignment | ||
Range on Protein: 1347-1625
Range on HMM: 2-285/290.0
IPITDLADNIERLKANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPG--SDYINANYIDGYRKQNAYIATQGPLP
||. .... .. .|. .| ......| |. ..| . . . ||..||.||.. || |..| | | . .|||| ||.||.....|||||||..
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS-SEKRELRQFQFMAWPDHG-VPEYPTPI
.|. |||...|..... .||.| |. .||| ||||...|.. | ....||. .| .|. |.. .... | .|... |.|. .|...| |... | .
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtil
LAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATC
|.. ...| ...|||||..|||.. |.... ....| | .|.. . .|.|. .|||..|| .|.. .|.. ..
lvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1381-1623 | 2.1e-73 | 241.7 | In-house | 32-275 (280) | alignment | ||
Range on Protein: 1381-1623
Range on HMM: 32-275/280.0
TWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGvpgsDYINANYID----GYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCD
. ..... | .|||| ....||. ||.|.. . |||||||.. . | ||||||||..|. |||.|||||.. ..||.| | |. ||||
aisaarkpenlsknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkCh
QYWPARGT-ETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIV
|||| . . | ..|.. . | .| .| . |... ..|.|.. |.|..||||||||. .. .| |..||... . |.|||||||.|||| .|.
qyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlil
IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
.. | . ... | . | || || .|||..|| |. ||.|..
letalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvy
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1351-1630 | 4e-73 | 241.3 | In-house | 6-286 (439) | alignment | ||
Range on Protein: 1351-1630
Range on HMM: 6-286/439.0
DLADNIERLKANDGLKFSQEYESIDP---GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMG
.. . .|.|. |. |....|.|. . | ...|||| .| |.||.||.| | ||| | |||||||.|| ... ||||||| ||
efqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettd
DFWRMVWEQRTATVVMMTRLEEKSRvkcdqYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSG--SSEKRELRQFQFMAWPDHGVPEYPTPILAFL
||||.|.|..|.|.||.| | | . |||. . | | | .|| |..| | . . . .| . ||...||||. || . .| ||
dfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldfl
RRVKACNP-LDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEV
| ....| . ||.|||||||||||| | .| ||..| |. ||| | |. .| ||. |||. |||||..|.|| | . |
rainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiav
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1678-1914 | 3.3e-71 | 235.0 | In-house | 42-276 (515) | alignment | ||
Range on Protein: 1678-1914
Range on HMM: 42-276/515.0
CNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSAR
| ||| ||.||. .|| |. | |||.|||.. .. .|||||.|||. |..||||.....| | |.|.|||.| . || .||| | .
infkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvk
YQYFVVDPMAEYNMPQYILREFKVTDARDgqSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqdGPITVHCSAGVGRTGVFITLSIVLERMR
. .. |. .. . | |...|. | |||. ||.||.||..|||| .. .| .| ..|. |. .|||||||||||.|.. |. ...
fGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt..hpliihcsaGvGrtGvvisidsvvahak
YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.||.|..|. .| .|| .|||..|| . | | ||.|
ttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1390-1621 | 4.4e-71 | 233.9 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 1390-1621
Range on HMM: 3-237/237.0
NKPKNRYANVIAYDHSRVILTSIDGVpgSDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARG-TETC
|| ||||.|..|||||||.| . ||||||.|..|. . |||.|||| . |||.|||... . .||.| | |. ..|| .||| ..
nkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GLIQVTLLDTVELATYTVRTFALHKSGS-SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTGCFIVIDAMLERMK
| . |.| |.. ||||.. | | .. | | . |.|| .|||.|||.. . .| | ... .| ..|| ..|||||||||| |.|||||| . |
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
.| |||| .| .. .| |..||.|||||||...||
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1658-1921 | 7.8e-71 | 233.4 | In-house | 26-285 (287) | alignment | ||
Range on Protein: 1658-1921
Range on HMM: 26-285/287.0
FKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQpirgVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLR
|..| . . . . . || |||| .|.... || |. | |||||.|.|||...||.|....|... .||......| |.||||....
ftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqek
EMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-DGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqDGPITVHCSA
| .|.|.|||| |.| . . . . | . .|| |...|. .|. ....|.|.|.|...| .. . . | . ||. . | ...| ||||.
endeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrg.ntsivvhCsd
GVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA
.|||...|. . ... . |||.|.|| .| | |.| .||| .||. . . |||| ||. |.
tvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1675-1915 | 3e-70 | 231.5 | In-house | 24-269 (274) | alignment | ||
Range on Protein: 1675-1915
Range on HMM: 24-269/274.0
NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEG-SDYINASFLDGYRQ-QKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER
... .. ||| .|.| | .||.|.. . . |.|||| .. ||.. .|||.||||||.. .|||||........|||||||.|. ..||..|.| ..
dvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdae
SA----RYQYFVVDPMAEYNMPQYILREFKVTDARDgqSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITL
.. ||. . . . .| .|.. . . . .|.. . .||||.. .|. . ..|.. .|....|. . .|. ||||||.||||.||.
dyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiai
SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
|| . ..| |.|||....| || .| ||||..||.| .|| .||
siavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1667-1907 | 3.4e-70 | 231.2 | In-house | 29-268 (280) | alignment | ||
Range on Protein: 1667-1907
Range on HMM: 29-268/280.0
HTSRFISANLPCNKFKNRLVNIMPYELTRVCLQpirGVEGsDYINASFLD----GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRE
|..| | ||| .|.||. ||| |. | |||||.... . . . |||||||||....|||.|.||..|..||||| | | ||
pglaisaarkpenlsknryrdilpydatrvklk...eset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrv
KCHQYWPAE-RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRT
||||||| . . .| | | | . .|.|||. ..|.. ..|.| |.|...||..|||. . |..|. .|.|... |.. |. ||||||.|||
kChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrs..gkeePvvvhCsaGigrt
GVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCY
||.|.| . | . . | . . |.|.| || ..|||..||..
GvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvC
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1377-1628 | 1.8e-69 | 228.7 | In-house | 19-276 (290) | alignment | ||
Range on Protein: 1377-1628
Range on HMM: 19-276/290.0
GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGvpgsDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCD
..|. ....|. |...||| .| |||||..| . | |||||. .. . . || ||||||.|.. ||.|||||.. .|||. .. ||...||
asdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikca
QYWPARGTETCG-----LIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGR
|||| | . ..|.|. . . .||||.. |.. . | ||. .| ...||| |||| |. | || .|. . | | || |.|||||.||
qywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGr
TGCFIVIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHT
.| |...|..| ...... ||| .. .|..| ..|| || | . |.|| | . ..
sGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikg
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1388-1630 | 9.3e-69 | 226.6 | In-house | 45-285 (287) | alignment | ||
Range on Protein: 1388-1630
Range on HMM: 45-285/287.0
EVNKPKNRYANVIAYDHSRVILTsidgVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETC
. ||.|||..... .| ||.| ||||| .||||....|.|....|. .|. .||....... ..||.....|. . .| |||| . .
sqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvl
GLIQVTLLDTVELATYTVRTFALHKSG-SSEKRELRQFQFMAWPDHG-VPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH
| ...||. | |..|.. ..... ...|....|.|. .|...| |.|. | .| . ...|. ...|||||..|||.. |. .. ... |
GeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckt
EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEV
| ..|.. . .| |. .||| .|| || ...|| ....| .
eGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1669-1914 | 1.6e-68 | 225.9 | In-house | 34-277 (315) | alignment | ||
Range on Protein: 1669-1914
Range on HMM: 34-277/315.0
SRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYW
.| .| . | ||| ||.|.. .|| |. | |||||||.. .. ..|||||.|||| | .|||||..... | |||.||..| . || |||
yrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqyw
PA--ERSARYQYFVVDPMAEYNMPQYILREFkVTdARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfgQDGPITVHCSAGVGRTGVFIT
| |... . |. . . . |.. || . .|||. |||||.||..||.| .. .| .| ... .. .. ||||||||||||.|.
PdrkadsvefGsikvellsleadtdgvarkl.vt.rkseesrtvtqfqftewPdkGvdkqtssllklikevkadngk..kefsllvhcsaGvGrtGvvis
LSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
. |..... . .||.|..||.||..|| .||||..| . | | ||.|
idevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1656-1915 | 3e-68 | 225.3 | In-house | 27-289 (325) | alignment | ||
Range on Protein: 1656-1915
Range on HMM: 27-289/325.0
LEFKLLASSKAHTsrFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTK
||.|| | . . . | .| || |||. |..... .||.|. . |||||||.| ..... ..|.| ||.....|.||.. . .....|.| .
hefgllpsddgia..kkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlne
LrEMGREKCHQYWPAE--RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQ----DGP
| . | ..| .||| | | .. . | .. .. |. | ..| ....|..|...|||. |.. ||.| .| .. |.. .|. .|
l.dlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastp
ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
| ||||||||||||||.| .|... | ||.|. || || .||.||.| ||| |.| | |..
ilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaym
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1667-1918 | 3.9e-67 | 221.5 | In-house | 39-288 (297) | alignment | ||
Range on Protein: 1667-1918
Range on HMM: 39-288/297.0
HTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQqkAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGReKCHQ
. |. | |.| ||.||. || |. . |||.||||. |... .|.|| | .. .|||.|..... ..||||... | . || .
niqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcar
YWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPK--TGEGFIDFIGQVHKTKEQFGQDgPITVHCSAGVGRTGVF
||. . .. . . .| .. . .| ||..|| . . | ..|.||..||.. |.. . . ....| .|.|. .| . |. |||.||||||||.
yWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaeg.PllvhclaGvGrtgvl
ITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD
.|. |. ... | ||.|..|| || .|| .|||..||.. | | ||.| | |
ltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsed
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1657-1916 | 1.3e-66 | 219.7 | In-house | 16-271 (273) | alignment | ||
Range on Protein: 1657-1916
Range on HMM: 16-271/273.0
EFKLLASSKAHTSRFiSANLPCNKFKNRLVNIMPYELTRVCLQpirgVEGSdYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLT
||| | |. . ... || ||| |..||. ||| |. ||. |||||.. .. |||.|||| |...|||.|.|| ....|.|.|
efkelrelkpldtce.vgkkkenkdknryrnvlPydetrvklg....degg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
KLREMGREKCHQYWPAERSAR---YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgQDGPIT
. .| |. |||.||| ... . .. . |. . .. .. .|...|.| . |.|| . ...|..||. |||.. . .. |. .| . .. . |||
lekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt...dagPiv
VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGS
||||||.||.|..||. .||. . . .|. ..|..|| || ..|||.||| ..|.|.|| |.|
vhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlks
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1679-1914 | 1.8e-66 | 218.9 | In-house | 20-264 (270) | alignment | ||
Range on Protein: 1679-1914
Range on HMM: 20-264/270.0
NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQ-QKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA--R
.| || .|.| |||.|.... . . |||| .. |. . .|.|||..|||. ....||||.||...| |||.|.| | ||.|| .|||||. .
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
YQYF--VVDPMAEYNMPQYILREFKVTdaRDGQSRTIRQFQFTDWPEQGVPKTGE------GFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITL
... | ..| .. |||.. ... ..|..| . |....||..|||.. . . . .|....... . .|. |||||||||||..|.|
ledgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlial
SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|... . .. ||. . .. || .|.|.||. .||.. |.| .||
DiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1387-1638 | 3.3e-66 | 218.0 | In-house | 30-281 (283) | alignment | ||
Range on Protein: 1387-1638
Range on HMM: 30-281/283.0
LEVNKPKNRYANVIAYDHSRVILTSIDGvpgsDYINANYID---GYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARG
. ||.|||. .....| || | | ||||| .| |.... ||..|.|| .|. |||.||.... ...||.|.| | |.|| |||| ||
adenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrG
TETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE-LRQFQFMAWPDHGvPEYPTPILAFLRRVKAC-NPLDAGPMVVHCSAGVGRTGCFIVIDAMLE
.| | ||| . . ..... . |....|... | .|. | . | .. . | . .|.. . ||.|||||.|.|||. || . | ..
sedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleyg.eqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvk
RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAH
.. | ||.. |. || || .||| ||| ..||. || | || |.. | .|..
daltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqst
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1346-1667 | 1.7e-65 | 216.0 | In-house | 3-280 (392) | alignment | ||
Range on Protein: 1346-1667
Range on HMM: 3-280/392.0
PIPITDLADNIERLKanDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPET
|||.... .|. . |..|. . . . .. |.|..|||| |.. || .||.| || .| |||.|| ||... ..||||.||| . .
pipvaqfpafveknr..hsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaas
MGDFWRMVWEQRTATVVMMTRLEEKSrvkcdqywpargtetcgliqvtlldtvelatytvrtfalhksGSSEKRELRQFQFMAWPDHGVPEYPTPILAFL
. ||||||......|..|.|.|.| ..| ||.| |||..||.. . .| |.
lddfwrmvfqenvttiamvtklkegd..........................................kgddartvaqfhftewPdkdvpkhtssllkfi
RRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQV
. ||| . |...|||||||||| | ||... . |. . ||.. || .| .| |||||..|| ||. |.|| | .| . |.|.|
kevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlsts
PPGESVTAMELEFKLLASSKAH
|. . . ||. | .|..
sdGdvrskqlkefrslkashtv
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1677-1914 | 5.1e-65 | 214.5 | In-house | 47-279 (315) | alignment | ||
Range on Protein: 1677-1914
Range on HMM: 47-279/315.0
PCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAErSARY
|| ||| .||..|. .|| | . ..|||.||.|.||| ... |||.|||...| .||||...|.. . |||||.| | ..|. .||| . |
ienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviy
QYFVVDPMAEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqdGPITVHCSAGVGRTGVFITLSIVLERMRY
. | . | .| | . |. . . |.. |...| ||. |||| ....| .|.. ... |.| ||||||||||| ||||. ||...
Gkitvtrkseevnteytvrtlsvvf..gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv..gaivvhcsaGvGrtGtfitldavldqaea
EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
| ..|... .. .| .| |||. .|||. | | || .
enaidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1650-1913 | 1.1e-64 | 213.0 | In-house | 13-279 (288) | alignment | ||
Range on Protein: 1650-1913
Range on HMM: 13-279/288.0
SVTAMELEFKLLASSKAHTSRFISAN-LPCNKFKNRLVNIMPYELTRVCLQpirgVEGSDYINASFLDGYRQQ-KAYIATQGPLAESTEDFWRMLWEHNS
.||.. .||.| ..... .| | .. ||| .|.||. .||.|. . |||||||. . . .||||.||... |||.|..| |
gktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqks
TIIVMLTKLREMGREKCHQYWPAERSA--RYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHK--TKEQ
.||||.. |.|..|...|||... . ... . | . ...... |..|.. . . .... |.| ||| |||.. | ...|...|.. ...|
sviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavq
FGQDGPITVHCSAGVGRTGVFI-TLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
. |. ||||||||||||| ..| | . .|..|. | |..||.|| |||...|.. .| | ||.
rksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1390-1622 | 1.4e-64 | 212.7 | In-house | 20-263 (270) | alignment | ||
Range on Protein: 1390-1622
Range on HMM: 20-263/270.0
NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQ-NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE---
.| ||||... ..||.| ... . . ||||||. |. .. ..|||..|||| |. .||||.||... ..||.| |||| | ||..||||. |
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
-TCGLIQVTLLDTVELATYTVRTFALHKSGSseKRELRQFQFMAWPDHGVPEYPT------PILAFLRRV-KACNPLDA-GPMVVHCSAGVGRTGCFIVI
. | |.|. | .. | .. |...|. .|.| |.. .|||||||. . .|. || | . .. || .|..|||||||||||..|..
ledgkikvlalseekeegyiltrlrleekge..errlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlial
DAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
| ... ....| ||. .. .| .| .||. .|| |...|..|
DiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavvey
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1657-1914 | 5.8e-64 | 211.0 | In-house | 28-296 (300) | alignment | ||
Range on Protein: 1657-1914
Range on HMM: 28-296/300.0
EFKLLASSKAhTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVeGSDYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLT
|. .. .. . . .|.|| |. ||| ...||| .|| |.| . ..||||| . ... ||..|||| .|||.|.||.. ..|||||
eyeripkkre.dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlt
KLREMGREKCHQYWPAE----RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQ----
. .| |.||...|.| . ...... | | . ...| . .|. .. ||. .|.||||..|||. .||.... .|. .... .
eeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves
---DGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
. |. |||||||||||| |. .... . . ..|. .....||.|| .||| ||. |.. ..||
keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1380-1621 | 1.3e-63 | 209.5 | In-house | 46-290 (297) | alignment | ||
Range on Protein: 1380-1621
Range on HMM: 46-290/297.0
FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYI-DGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQY
| | .. | | |||...|..|||||| |.. |||||| | | .. |||||||||..|. |||.||||| .. .|..|||||.. .|..|
stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry
WPARGTETCGLIQVTLLD-TVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVID
|| |.|. .. .| |. . | ||.| | .|| | . || |..||..||| . ..| | |.| . . |.|||||.|.||||..|.||
wpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilid
AMLERMK-HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
.|.|.. | .|| . .| ||. .|.|.||. |. |. |
lvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1679-1914 | 1.8e-63 | 208.9 | In-house | 42-290 (296) | alignment | ||
Range on Protein: 1679-1914
Range on HMM: 42-290/296.0
NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGReKCHQYWPAERSARYQY
|. ||| |...||. .|| |. . | | ||||||.. |.. ..|.|| |..| |. ..|||....... .|.||| .. . ....||| . ..|.
nreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyge
FVVDPMAEYNMPQYILREFKVTDA----------RDGQSRTIRQFQFTDWPE-QGVPKTGEGFIDFIGQVHKTKEQF---GQDGPITVHCSAGVGRTGVF
..|. . | .... |.||.| . . |....||.| |. . || ...|... .|.. .|. . ||. |..| |..|.||.
ifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvy
ITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
... . || .. |. ||.|. ||||| .|| .|.. ..|. .| ||..
laidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1377-1620 | 3.7e-62 | 204.7 | In-house | 25-274 (287) | alignment | ||
Range on Protein: 1377-1620
Range on HMM: 25-274/287.0
GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILtSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCD
. .|. ... . |||||.|. .|..||.| | .| |||||||||. .|....|.||.|||.. |..||||.|.|.|.|.|..||| |..| ||
sstatfkaaeelaavkknryadvlPiddtrvll.saegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcy
QYWPARGTE-TCGLIQVTLLDTVEL-ATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRV-----KACNPLDAGPMVVHCSAGVGR
.||| | | |.||| . |.||.. | . . | | ..|.....|||.... .. | | | . ..||.|||...|.||
kywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGr
TGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALL
.| .. . ....|.. ||. | .| .|. .||. |. .. |||
sGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1390-1627 | 8.1e-62 | 203.5 | In-house | 42-294 (296) | alignment | ||
Range on Protein: 1390-1627
Range on HMM: 42-294/296.0
NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRvKCDQYWPARGTETCGL
|. |||. .|. ||. ||.|...|| |||||| |.|.. |...|| |..| ||...|||.|... . .||..|. . .. .. .||| .. | |
nreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyge
IQVTLLDTVELATYTVRTFALHKS----------GSSEKRELRQFQFMAWPD-HGVPEYPTPILAFLRRVKACNP-L----DAGPMVVHCSAGVGRTGCF
| | .. . ..| . ||| | | . |.| ...||. |. . || . .. ..|||. . ||.||..| |..|.| .
ifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvy
IVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGH
. ||| || ...|. ||... | .| .|. .|.. ..| .| . |||| |.
laidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1677-1920 | 8.9e-61 | 200.2 | In-house | 38-299 (301) | alignment | ||
Range on Protein: 1677-1920
Range on HMM: 38-299/301.0
PCNKFKNRLVNIMPYELTRVCLQPIRG--VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA
|| || || .|. |. |.| . . .|||||..|||...|..||.|||. . ||||..|.. . |||.|.|.| ..||.|||| .
eenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseae
RY--QYFVVDPMAEYNMPQYILREFKVT--D-------------ARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqDGPITVHCSAG
.. | | . |...|....|...|. | .| .|... |.| ||||..|| . . | .| ... . | ||. ||||..
seefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkig.ggpvvVHCSdt
VGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHY
|.|.||....|| || . |||||.|| .|..| ..| .|.| .|| | . .|| . |
VsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1388-1623 | 1.9e-60 | 199.2 | In-house | 41-280 (288) | alignment | ||
Range on Protein: 1388-1623
Range on HMM: 41-280/288.0
EVNKPKNRYANVIAYDHSRVILTsidgVPGSDYINANYIDGYRKQ-NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTET
... |||. ... |||.|| | ||||| .. . . .||||.||..|..|||.||.||.. ..||.. ||. . |.|.|||.. ||
klyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkget
--CGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD----AGPMVVHCSAGVGRTGCFIVIDAM-
| ..||| .. |. |. |.. |. ......... |...||..|||. | .|.|| |... |.|||||||||||| | .. |
vkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaav
LERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
| |.. .|| | .| || .|||...|. | || ||||
relekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1368-1620 | 2e-60 | 199.4 | In-house | 26-293 (300) | alignment | ||
Range on Protein: 1368-1620
Range on HMM: 26-293/300.0
SQEYESIDPGQQ-FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVpGSDYINANYIDGY--RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM
.||| | . .. . . ..|..|..|||. .|. |...|| |.. ..|||| | |. ||..||||. |. |||.||||| .. .||.
fteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivml
TRLEEKSRVKCDQYWPARG----TETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN-----PL-
|. ||. . |. .|.| . | . | .|| . . ... ... |. |.|.|.. .|.. |||||||| ... | .|..|..
teeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseve
---DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALL
|..||||||||||| |. | ... ..|....|| .. .| || ..||| || |....|.
skeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvli
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1654-1912 | 2.9e-60 | 198.5 | In-house | 31-290 (297) | alignment | ||
Range on Protein: 1654-1912
Range on HMM: 31-290/297.0
MELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFL-DGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVM
.| |.. |.. .|. | |. . | ||| ...||. .|| |. | |||||||.. | .. ||||||||||.. |||.|.||. ...||.
lekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivn
LTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNM-PQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPIT
||.|.| | ..|..||| | |. |. . |. ..|. .|..| | . . . ..||. || | |||.||| . ...| .| |. |. ||
ltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr..Grscpiv
VHCSAGVGRTGVFITLSIVLERMRyEG--VVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
||||.|.|||||.| . .||.|. | .|. |.. || ||| .|.|.||..... | |
vhcsdGaGrtGvyilidlvlnrll.kGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1678-1913 | 8.4e-60 | 197.0 | In-house | 32-265 (283) | alignment | ||
Range on Protein: 1678-1913
Range on HMM: 32-265/283.0
CNKFKNRLVNIMPYELTRVCLQPIRGvegsDYINASFLD---GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA
|| ||| .|.|.. || |.. |||||.|. |.|.| ||..|.|| . |||.|..... | |||||||.| |.|| |||| . |
enkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGse
RYQYFVVDPMAEYNMPQYILREFKVTDARDGQSR-TIRQFQFTDWPEQGVPKTGEGFIDFiGQVhKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLER
| | | |. .| .|. . .| . .|. || | | . .. | .| ... . ..||| ||||.|.|||.|||..| ..
dyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkf.nkv.islqteskkgPivvhCstgiGrtavfiaasasvkd
MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
.. | |||.|..|| .| ||. .||| |||.| . ..||
altesvvdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1679-1914 | 1.5e-59 | 196.6 | In-house | 48-279 (439) | alignment | ||
Range on Protein: 1679-1914
Range on HMM: 48-279/439.0
NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRekchqYWPAERSARYQY
.. ||| .. ... ||| || | || | |||| ...|| ..| ||||||| |.|.||||...|.... |||||.| | . |||.. . |
dqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygd
FVVDPMAEYNMPQYILREFKVTDARDG--QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVLERMRY
.| . ..|.|..| ||| . || . ||. ||... ||.. || .||. . .... . ||. ||||||||||| |.| | ||...
iavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandk.eeygpvvvhcsagvGrtGtiialdialeqlkl
EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
| ||. || || || |||. || . | | || .
enkvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1660-1913 | 3.4e-59 | 195.0 | In-house | 19-276 (287) | alignment | ||
Range on Protein: 1660-1913
Range on HMM: 19-276/287.0
LLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQpIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREM
| |.. | | .|. . ||| ...|.. ||| | | ||||||| .. .|....|.||.|||.| . ||||...|..|. ....|. |
lkedsesstatfkaaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtrevee
GREKCHQYWPAERSA-RY-QYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQV--HK-TKEQFGQDGPITVHC
.| ||..||| . | | || . |.| | ... |. ..| ..|... .||..... | |.| |. .| | . . . ||. ||.
arlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhd
SAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
..|.||.|..... ....|. | ||. ..| || .| |.||. |..| | | |
dvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvty
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1415-1642 | 4.4e-58 | 192.3 | In-house | 1-243 (272) | alignment | ||
Range on Protein: 1415-1642
Range on HMM: 1-243/272.0
VPGSDYINANYIDGYRK---QNAYIATQGPLPETMGDFWRMvWEQRTATVVMMTRLEEKSRVKCDQYWP------------ARGTETCGLIQVTLLDTVE
.| |.||||....|| . .......|||| | ||||. .|.. |.|.....||. |.|||.||| . | . | . |||| ..
lplsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
LATYTVRTFALHKS-GSSEKRELRQFQFMAWPDHGVPEYPtpILAFLRRVKAcnpldAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVD--------
| |..|.. |.. . .| ||........|||||||. . .|..|. . . ||..||||||..|||...... .|... .| ||
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
IYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAaTCGHTEVPARNLYAHIQKL
... | .|.|| ..||||.||.|..|||||. .....|.|. | |... .
leeaveelraqrpgavqteeqylflyeallel.lrsllsvraeyllaaldai
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1363-1625 | 3e-57 | 188.6 | In-house | 13-295 (301) | alignment | ||
Range on Protein: 1363-1625
Range on HMM: 13-295/301.0
DGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDG--VPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTAT
||...|.... |.. . . . | ||. ||. |. ||. |.||. . .||||.|||||......||.|||. .|. ||||..|......
hsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
VVMMTRLEEKSRVKCDQYWPA--RGTETCGLIQVTLLDTVELATYTVRTFAL---------------HKSGSSEKRELRQFQFMAWPDHGV-PEYPTPIL
.||.| |.|... || |||| .|. | ..||| .. . ...| ... ... . . ... |.| ||..|| .|. | .
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLq
AFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATC
. ... . . ||.|||||..|.|.| .. .. || | | ||... . .| .. .|.| .||..|.... . ..
viddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylql
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1679-1912 | 5.1e-57 | 187.8 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 1679-1912
Range on HMM: 3-237/237.0
NKFKNRLVNIMPYELTRVCLQPIRGveGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA-ERSARY
|| ||| ||. |. .|| |. . |||||||..|.|. | |||.|||| | .|||.|.|. . ..||||| | | ..|||.||| .. | |
nkiknrygnivaydhsrvvlkgags..gsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
QYFVVDPMAEYNMPQYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR
. | . .. .| .| . .. . | | |.||| ||..|||. .. | .. . . . || .||||||||||.|. . .| . .
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
. |||... |... .|| ..||.||| . ... ||
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1666-1912 | 2.3e-56 | 185.6 | In-house | 19-269 (290) | alignment | ||
Range on Protein: 1666-1912
Range on HMM: 19-269/290.0
AHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGvegsDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCH
|. . .|.|| |. .|| .. ||. .|. |. ||||||... . .. || |||||.. .. ||.|.||..| .||| |. | .. ||.
asdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikca
QYWPAERS---ARYQ--YFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGR
|||| . . .. . |. ..| . .|..| ..... . ..|.| .| .| ||. |||.. |..|. .| .. . || .|||||.||
qywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGr
TGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
.| |. . .| .. .. ||. ... || .| ..|| || .. | | ||
sGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1705-1916 | 2.7e-56 | 186.5 | In-house | 2-227 (272) | alignment | ||
Range on Protein: 1705-1916
Range on HMM: 2-227/272.0
EGSDYINASFLDGYRQ---QKAYIATQGPLAESTEDFWRMlWEHNSTIIVMLTKLREMGREKCHQYWP------------AERSARYQYFVVDPMAEYNM
. |.||||....|| . .......||| . .||||. .|.. . ||.|... |.||.||..||| .. . .| ...| . |...
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
PQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGegFIDFIGQVHKtkeqfgqDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD-------
. |||||. .| |..|.......|||| |||. ..... .... .||. ||||||..|||... | ..|... .| .||
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnl
-MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGS
....|. || |||..||||.||. .|.|.||.| |
yleeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1678-1912 | 9.4e-56 | 183.6 | In-house | 6-238 (239) | alignment | ||
Range on Protein: 1678-1912
Range on HMM: 6-238/239.0
CNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSaRY
|| ||| ||. |. .|| |. . |||||||.| | |||||||| .. |. |||||.|. .||||| | | ..||||||| | .|
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.ky
QYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVhkTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRY
. | . .||.| | ... . . | . |..|| ||..|||. . . .. ||. . | .|||||||||| |. . .| . .
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki..tkdslpgarpwvihcsagvgrtgaflvidamlrqakk
EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
. ||.|. ||..| .|| |||| .|| . . | ||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1678-1912 | 1.2e-55 | 183.2 | In-house | 7-239 (239) | alignment | ||
Range on Protein: 1678-1912
Range on HMM: 7-239/239.0
CNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSaRY
|| ||| ||. |. .|| |. . |||||||.| | |||||||| .. |. |||||.|. .||||| | | ..||||||| | .|
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.ky
QYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVhkTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRY
. | . .||.| | ... . . | . |..|| ||..|||. . . .. ||. . | .|||||||||| |. . .| . .
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki..tkdslpgarpwvihcsagvgrtgaflvidamlrqakk
EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
. ||.|. ||..| .|| |||| .|| . . | ||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1673-1914 | 2.1e-55 | 182.7 | In-house | 39-236 (392) | alignment | ||
Range on Protein: 1673-1914
Range on HMM: 39-236/392.0
SANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGrekchqywpaer
.|. . |. ||| ||.||. .|| |. | . |||.|||..... ..|||||.||| | | .|||||....| | |.|.|||.|
vaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd............
saryqyfvvdpmaeynmpqyilrefkvtdaRDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVhktKEQFGQDG-PITVHCSAGVGRTGVFITLSIVL
. . ||. ||.||.||...||| .. || .| | .||| |. .||||||||||| |.. |.
..............................kgddartvaqfhftewPdkdvpkhtssllkfikev...kadfGqythpliihcsagvgrtgvvisidsvv
ERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
. . .||.|. | .| .|| ||||..|| . | | || |
ahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1390-1630 | 3.7e-55 | 181.6 | In-house | 1-178 (182) | alignment | ||
Range on Protein: 1390-1630
Range on HMM: 1-178/182.0
NKPKNRYANVIAYDHSRviltsidgvpGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTrleeksrvkCDQYWPargtetcgl
|..|||| ... ||||| ..||||||...|..... .|||||||..|. ||.||..|.. |.|..| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
iqvtlldtvelatytvrtfalhksgSSEKRELRQFQFMAWPDHGVPEyPTPILAFLRRVKAcnplDAGPMVVHCSAGVGRTGCFIVIDAMLERmkhekTV
. ..|. |.... |||||||. . .|.|...|.. . || .|||||||||||...... |... |
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gv
DIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEV
... | .||.|. ||.|..||.|.. |||| .. |..
sleeavklvrsrRpgmvitpnqyfflqlallellllkktrp
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1417-1617 | 2.4e-52 | 172.4 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 1417-1617
Range on HMM: 1-164/174.0
GSDYINANYIDGYRKQNAYIATQGPLPetmgdFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPArgtetcgliqvtlldtvelatytvrtfalhkSGSS
|||||||...|... . .||.||||. ||.|..|.. ||||.....|. ..|| .||| ..
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
EKRELRQFQFMAWPDHGVPEYPTpILAFLRRVKACNPL-DAGPMVVHCSAGVGRTGCFIVIDAMLERMKhEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
..|. |.... |||||||. .. .| |...|. . . ||..|||||||||||...... || ... |..||.. .| .|.|| .||||..|| |.
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl
HE
..
yy
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1706-1908 | 2.6e-52 | 172.3 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 1706-1908
Range on HMM: 1-164/174.0
GSDYINASFLDGYRQQKAYIATQGPLAestedFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAersaryqyfvvdpmaeynmpqyilrefkvtdARDG
||||||||.||... . .||.||||| ||.||.|...|..|||....|.|..||..||| |.
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
QSRTIRQFQFTDWPEQGVPKTGEgFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVLERMRyEGVVDMFQTVKTLRTQRPAMVQTEDQYQL
.|.. |.... || ||| . . ...|. .|.. .. ...||. |||||||||||... . ..| ... |..|| ...|..||.||| ||||..||.
lerlgiqylylpwpDhgvpdlsi.llefvkfveealse.dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
CYR
.|
lyy
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1679-1914 | 5.4e-52 | 171.3 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 1679-1914
Range on HMM: 1-171/182.0
NKFKNRLVNIMPYELTRvclqpirgveGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTklremgrekCHQYWPaersaryqy
|. ||| ..|.||. .| ..|||||....|.. .. .||||||| ....||.|||.|.. |.||.|| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
fvvdpmaeynmpqyilrefkvtdarDGQSRTIRQFQFTDWPEQGVPKtGEGFIDFIGQVHKtkeqfgQDGPITVHCSAGVGRTGVFITLSivleRMRYEG
. |.. |.... || ||| . ..||| .|.. ..||. |||||||||||... . |.. |
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle......eggpvlVHCsaGvgRtgtlvaay....lmkklg
vVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|.....||..| .|| ||.|..||.....|.||.|
.vsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1376-1622 | 3e-49 | 162.2 | In-house | 42-282 (290) | alignment | ||
Range on Protein: 1376-1622
Range on HMM: 42-282/290.0
PGQQFtwENSNLEVNK--PKNRYANVIAYDHSRVILTsiDGVPGsDYINANYIDGYRkqNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRV
|.|.. | . .. | |||| .|. | .|||| || .| ||. |||..| . .| |||.| .|. |.|||| ....|..||. | |. .
pvqyl..erkifdkntefkknrykdvvcndktrvilk..dGydG.dyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGka
KCDQYWPARGTETCGLIQVTLLD---TVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACnpldAGPMVVHCSAGVGRT
||.||.| . |. . ..|.| . . | .|... . | . |. .. ..|||. |. .| || .. .||.|||||||.|||
kceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrt
GCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
| |. |.. |. . . | .|. . | .| | || . ||. . |.||.
GtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1416-1617 | 1.6e-47 | 156.8 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 1416-1617
Range on HMM: 3-155/172.0
PGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLeeksrvkcdqywpargtetcgliqvtlldtvelatytvrtfalHKSGS
.|||||||.|.|.|.. . .|||||||..|. |||||..|. ..|..|.| . ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
SEKRELRQFQFMAWPDHGVPeYPTPILAFLRRVKA-CNPLDAGPMVVHCSAGVGRTGCFIVIDAMLermkheKTVDIYGHVTCMRSQRNYMVQTEDQYVF
..|. |.... ||||||| . .| ||. .. .. . ||..|||||||||||...... || . .... | .|..|...||...|| |
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
IHE
...
lyy
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1386-1623 | 5.2e-47 | 155.3 | In-house | 37-277 (307) | alignment | ||
Range on Protein: 1386-1623
Range on HMM: 37-277/307.0
NLEVNKPKNRYANVIAYDHSRVILTsIDGVpGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE
.. | |||| .| . |..|.... .||. |||| |||. | . .|..|||| .|. .|| |. ... .|.|. .. | ...||.||||. .
afsantdknryqdvkcqdkgrivvk.fdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegq
T------CGLIQVTLLDTVELAT--YTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFlrrVKACNpLDAGPMVVHCSAGVGRTGCFIVID
. | |. | . .|| . .|. ... | ....|. |||.|||. . . ..| . | |.||||||||||.| . |
klvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainl...leavr.ydtnpvvvhcsaGvGrsGtivais
AMLERM-KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
. ..| . . |. | .||||.| .||| ||...| |||
lvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1662-1914 | 7.5e-47 | 155.9 | In-house | 29-280 (314) | alignment | ||
Range on Protein: 1662-1914
Range on HMM: 29-280/314.0
ASSKAHTSRFISANLPCNKFKNRLVNIMPYElTRVCLqPIRGVEGSDYINASFLDGYrqqKAYIATQGPLAESTEDF----------WRML--WEHNSTI
| . |.|..|. ||| .|.|.. .||.| | .|.||||||||..||. ...||||||| . .|| ||| ...|. .
slsvlpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrd
IVM---------------------LTKLREMGrekchQYWPAERSARYQyfvvdpmaeynmpqyilrefKVTDARDGQSRTIRQFQFTDWPEQGVPkTGE
||| |..| . | ...|.. . .. .... .. .|.. .. ...| ..| . |
ivmsrdevladelsrLdaAlgKtpllildgng.....neptaadlellk....................eelydpelferlgikylripvpDgsap.lle
GFIDFIGQVHKTkeqfGQDGPITVHCSAGVGRTGVFITLSIVLERMryeGVvDMFQTVKTLRTQRP-----AMVQTEDQYQLCYRAALEYL
| .|. ... ..||. |||.||.||||.|... ... .. || .. .... .| .|| .... .||. ...| ||||
dfdeflefieea....dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleyl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1384-1623 | 1.7e-46 | 153.4 | In-house | 27-259 (267) | alignment | ||
Range on Protein: 1384-1623
Range on HMM: 27-259/267.0
NSNLEVNKPKNRYANVIAYDHSRVILTSIDgvpgSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKsrvKCDQYWPARG
| | |. .||. ... ||..|||| . .|||| |..||...||.|.||.|| |..||. .. .|. ...|..|. . . ..|| .
qsiaeknqernrlddnlpyddtrvilrtke....eeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirlfwPPkm
TETCGLIQVTLLDTVE--LATYTVRTFALHKSGSSEkRELRQFQFMAWPdhgVPEYPTPILAFLRRVKACNPLDAG--PMVVHCSAGVGRTGCFIVIDAM
.. ..|. ..| | . |. |. | ... . . | . | | | . | | |. | |.||.||.||||.| |.|||..
gqakkyqdltvehslekeendyqiitlelkfknesa.hnvtlyyykkwn...intnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsq
LERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
|||.|.| ..||. . .|||| .|.| ..|..||| | | |
leraktegvsdifdflrkirsqriglvdtkeryiyihellaeya
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1412-1620 | 1.8e-46 | 153.4 | In-house | 6-170 (176) | alignment | ||
Range on Protein: 1412-1620
Range on HMM: 6-170/176.0
IDGVPGSDYINANYIDGYRkqnaYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCgliqvtlldtvelatytvrtfalh
. ...||||||.|.|.| .||||||||.|. ||..|..|.. .||..| . |..|.||..||| .. .
lgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi........................
ksgssekrelrQFQFMAWPDHGVPEYpTPILAFLRRVKACNPLDaGPMVVHCSAGVGRTGCFIVIDamleRMKHEKTVDIYGHVTCMRSQRN-YMVQTED
|.... |||||||.. . .| .|. .. . . || .||||||.||||...... ...|| .... . .|.|| ..|||..
...........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpe
QYVFIHEALL
|| |..|..|
Qyrflyefel
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1385-1585 | 2.7e-46 | 153.2 | In-house | 42-258 (418) | alignment | ||
Range on Protein: 1385-1585
Range on HMM: 42-258/418.0
SNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGY-RKQnaYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPA--
. . | ||||.|.. .|.|| | |. |||||||||||| || .|.||||||.|. ||||||||.| .||..| |. |.|||.|||
gdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkq..fictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqi
---------RGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC----NPL--DAGPMVVHCSAG
| | | | |.. .. . | .. . | |.. |.|. |||| .|.. |. .|. . | |..||||||
ggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsag
VGRTGCFIVIDAMLERMKH
||||| | |.... |
vgrtgtfctavimmkkldh
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1705-1907 | 5.7e-46 | 151.7 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 1705-1907
Range on HMM: 3-154/172.0
EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLremgrekchqywpaersaryqyfvvdpmaeynmpqyilrefkvTDARD
|||||||||.||.|. . .||||||| . ..||||||.|.. |.||.||.| . ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
GQSRTIRQFQFTDWPEQGVPkTGEGFIDFIGQVHKTKeQFGQDGPITVHCSAGVGRTGVFITLSIVLERMryegvvDMFQTVKTLRTQRPAMVQTEDQYQ
. .|.. |.... || .||| . | ...|. .... . ..||. |||||||||||... . ..|... .....|...|..|| .||...||.
llerlgiqylylpwpDhgvp.llellleflefidell.alspggpvlVHCsaGvgRtgtlvaaylmllgl......sleeavalvrekRpgavqnpsqyr
LCY
..|
fly
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1665-1912 | 2e-45 | 149.9 | In-house | 19-293 (297) | alignment | ||
Range on Protein: 1665-1912
Range on HMM: 19-293/297.0
KAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQpiRGVEGSDYINASFLDG--YRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRE
.|.. | ||. . ||| .|. .. ||| |. |.. ..||||| .. .. || .|||| .. .|||....|.. .|||..||.| ||.
eargesfssakrnsslrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrd
KCHQYWPAERSARY--QYFVVDPMAEYN--MPQYILREFKVTDArdGQSRTIRQFQFTDWPEQGVPKTGEGFIDF-----------------IG------
|| ||| | .||. .... . || |... .|| .| || ||. ||| | | .
kcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyr..sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamv
--QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
|. . . .. .. |||||||||.|| . ..|...| . . |. .. || ||. .||| .|..|.| |.|.
flqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1698-1915 | 2.1e-45 | 150.0 | In-house | 3-174 (176) | alignment | ||
Range on Protein: 1698-1915
Range on HMM: 3-174/176.0
LQPIRGVEGSDYINASFLDGYRqqkaYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYqyfvvdpmaeynmpqyilref
|... ...|||||....|.| .||||||| ....||..||.|.. |..|.||...|.|| ||..||| .... .
lrllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.....................
kvtdardgqsrtirQFQFTDWPEQGVPKTgEGFIDFIGQVHKTKEQfgqDGPITVHCSAGVGRTGVFITLSivleRMRYEGVVDMFQTVKTLRTQRP-AM
|.....||. ||| | ..... .... .. .||. ||||||.||||... . ...| ..........| ||| .
..............qylhlpwpDhgvpdl.elllellefirealke...ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplga
VQTEDQYQLCYRAALEYLG
|||..||. .|...|..|.
vqtpeQyrflyefellllk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1380-1624 | 2.4e-44 | 147.7 | In-house | 36-281 (314) | alignment | ||
Range on Protein: 1380-1624
Range on HMM: 36-281/314.0
FTWENSNLEVNKPKNRYANVIAYDhSRVILtSIDGVPGSDYINANYIDGYrkqNAYIATQGPLPETMGDF----------WRMV--WEQRTATVVM----
.|. ..|..|. |||| ... .| .|||| . .| |||||||.|.||. ...|||||||..|. || |||| ..... ..||
ltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrde
-----------------MTRLEEKSrvkcDQYWPARGTETCgliqvtlldtvelatytvrtfalHKS--GSSEKRELRQFQFMAWPDHGVPeYPTPILAF
..| .. .....|. . . .. .|. .. . .||...| . ...|
vladelsrLdaAlgKtpllildgng....neptaadlellk.......................eelydpelferlgikylripvpDgsap.lledfdef
LRRVKACnpLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHeKTVDIYGHVTCMRSqRN---YMVQTEDQYVFIHEALLEAAT
|. .... . || .|||.||.||||.|.|.. .. ... ... .| .|. | .... .||.||.|||||.
lefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRp.inpnpgfieqleqyefilealleylk
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1425-1617 | 3.1e-44 | 145.6 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 1425-1617
Range on HMM: 1-144/152.0
YIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWpargtetcgliqvtlldtvelatytvrtfalhksgssekrelrQF
.||||......||||||.|.|. |||||..|. |.||.|.|.|. ..||.||. |.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qy
QFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLermkheKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE
... |||||||. . .| .|. .. .. . || .|||||||||||...... || . |... | .|..|...|....|. |..|
lhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1651-1914 | 2.1e-43 | 143.5 | In-house | 15-277 (307) | alignment | ||
Range on Protein: 1651-1914
Range on HMM: 15-277/307.0
VTAMELEFKLLASSKAHTsrFISANLPCNKFKNRLVNIMPYELTRVCLQpIRGVeGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTII
|.|. ||. || . .. . .| ||| .. . .|. .. . |. |||| | .| . | .|..|||| .. .|| | ... .
vqalvdefrvlakktpeg..vtveafsantdknryqdvkcqdkgrivvk.fdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesv
VMLTKLREMGREKCHQYWPAERSARYQYFVVDP-MAEYNMPQY-------ILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHktke
.|| |. |... ||.||||.|. . . .. |. .. .. ..||||...|...||..|||.. . |... |.
imlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr....
qfGQDGPITVHCSAGVGRTGVFITLSIVLERM-RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.. |. |||||||||.| ...|.| ..| . . || . |. ||.||. .||| || .| |||.
..ydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1714-1907 | 2.4e-42 | 139.5 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 1714-1907
Range on HMM: 1-143/152.0
FLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWpaersaryqyfvvdpmaeynmpqyilrefkvtdardgqsrtirQF
|.|||......||||||. ....||||||.|.. |.|||||.| |.|..||.||. |.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qy
QFTDWPEQGVPKTGEGFIDFIGQVHKTkeQFGQDGPITVHCSAGVGRTGVFITLSIVLermryeGVVDMFQTVKTLRTQRPAMVQTEDQYQLCY
... || |||. . ..... ..| . ..||. |||||||||||... . ..| |.....|. .|..|| .|....|....|
lhlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1653-1913 | 1.1e-41 | 137.6 | In-house | 7-258 (267) | alignment | ||
Range on Protein: 1653-1913
Range on HMM: 7-258/267.0
AMELEFKLLASSKAHTSRfISANLP-CNKFKNRLVNIMPYELTRVCLQpirGVEgSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIV
.| ||.|. .|. || .. |. .||| . .||. ||| |. | .|||||...||....|.|.||.|| . ||. .. ... ..||
eiekefelikkisdtsst.isqsiaeknqernrlddnlpyddtrvilr...tke.eeyinasyvegyktknafivtqdplkntitdfltvihdqkvpviv
MLTKlreMGREKCHQYWPAE--RSARYQYFVVDPMAEYNMPQY--ILREFKVtdaRDGQSRTIRQFQFTDWPEQGVPKTgeGFIDFIGQVHKTKEQFGqD
.||| . .. ...|| . .. .|| ..|. | . .| | |.|. .. .. . . . | . | . ..| . | . . | .
lltk...vftdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkf...knesahnvtlyyykkwnintnnkp..ylkplfgilaknqleng.n
GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
|. |.||.||||.| |... |||.. |||.|.|. .. .| ||...|.| ..| ... ||
rPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1369-1631 | 4.7e-41 | 135.3 | In-house | 31-297 (310) | alignment | ||
Range on Protein: 1369-1631
Range on HMM: 31-297/310.0
QEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTsIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLE
..| .| |. . . . ||||..|. | ||| |. || ||| |||. ....| .|||| |. |||||....|. ..... .
kqyrkldakqdssltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvg
EKSRVKCDQYWPARG-TETCGLIQVTLL----DTVELATYTVrTFALHKSG----SSEKRELR--QFQFMAWPDHGVPEYPTPILafLRRVKACnpLDAG
|. | || |||. | ||| | |.|| | . |. .| || . .. .||| .. ||| |||. . .|. | . |
eegrpkcvgywpslgvtetygcirvtnlsesseefeicnlav.tfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtv..pqrllaq..vrhg
PMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAtCGHTEVP
| |||||||..|... . .. ...... . ||. .| .. .| .||| ||..|. . | |.|||
pcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifa.rgeteva
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1369-1621 | 7.6e-41 | 134.7 | In-house | 34-287 (305) | alignment | ||
Range on Protein: 1369-1621
Range on HMM: 34-287/305.0
QEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILtsiDGVPGSDYINANYIDGY-RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRL
| | |. | .... ||||..| . |.| | | | . |||| |||. .. .|..|||| .|. .|| || ... .||. .
akytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkl...dkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlckt
EEKSRVKCDQYWPARGTETCGLIQVTLLDTVELAT-------YTVRTFALHKSGSsEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpldaGPMV
| ..|| ||||| | | ... | . . .. | ||. .| .|..|. ||| ||| | .| .. . |.|
velgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgd.qkmsvrhlqwtewpdrgvppckltslellsairgsk....vpiv
VHCSAGVGRTGCFIVIDAMLERMKHEKTVD-IYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
||||||.|||| . |. .||.. .| . . | ..| || . .|.. ||.||| .|.
vhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmln
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1384-1622 | 1.9e-40 | 133.3 | In-house | 31-268 (281) | alignment | ||
Range on Protein: 1384-1622
Range on HMM: 31-268/281.0
NSNLEVNKPKNRYANVIAYDHSRVILTS-IDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPaR
| ||. ||||.|. . | ||| | . .||| |||| . || |||| || |||||.|.. |...||. .. | | || .|.| |
vfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfp.r
GTETCGLIQvTLLDTVEL--ATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACnpldAGPMVVHCSAGVGRTGCFIVIDAML
. | .. | . | .. | | | | | . .. . ||| ||| .| ||...| . | |.||||||||.| .. .. |
nahcclqfd.klsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirar....stppvihcsagvgrsgtlmaveial
ERMKHEK-TVDIYGHVTCMRS-QRNYMVQTEDQYVFIHEALLEA
. .. || |. .| | ||| .||..| . ||.
qsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1706-1910 | 3.4e-39 | 129.2 | In-house | 2-149 (151) | alignment | ||
Range on Protein: 1706-1910
Range on HMM: 2-149/151.0
GSDYINASFLDGYrqqkaYIATQGPlaesTEDFWRMLWEHNSTIIVMLTKLREMGreKCHQYWPAERsaryqyfvvdpmaeynmpqyilrefkvtdardg
|||||.|...|. .....|| ..||...|.|.. . ||.|... |.| .|..|.|..
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
qsRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKtkeqfGQDGPITVHCSAGVGRTGVFITLSIVLERmryegvVDMFQTVKTLRTQRPAMVQTEDQYQL
.........|||..|.| . . ...|. .. . ..||. ||||||.||||... | ..|.. |....... .| .|| .||...|...
..ievlhipildwpdpglplsfdavleflellld.....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
CYRAA
...|
qlfal
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1654-1874 | 6.1e-39 | 128.9 | In-house | 23-256 (418) | alignment | ||
Range on Protein: 1654-1874
Range on HMM: 23-256/418.0
MELEFKLLASSKAhTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRqQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.. ||.|| | | . | ||| ||.| . ||| |. |. |||||||| ..|| | .|.||||| .. |||||.|| |||||
ikeefrlleesvg.psetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgay.pkqfictqgplpntiadfwrmvwenrcriivml
TKLREMGREKCHQYWPAERSArYQYFVVDP----MAEY-----NMPQYILREFKV---TDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTK
.. | | || .||| . |. . . | .. | || . .|..| | |.|. ||.. .| . | ... . . .
sresencrikcdrywpeqigg.eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrq
EQF----GQDGPITVHCSAGVGRTGVFITLSIVLERM
.| .. || ||||||||||| | | |.....
nqiipssdrnvpiivhcsagvgrtgtfctavimmkkl
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1690-1913 | 1.9e-38 | 127.2 | In-house | 1-170 (178) | alignment | ||
Range on Protein: 1690-1913
Range on HMM: 1-170/178.0
PYELTRVCLQPIRGVEGSDYINASFLDGYrqqkAYIATQGPlaestEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSaryqyfvvdpmaeynm
|.. |||.|....|.|.|||||||. ... |.....| .|....|.|.. | ||.||. |.|..||..||| | .
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
pqyilrefkvtdardgqsrtiRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRTGVFITLSIVLERmryeGVvDMFQTVKTL
|.... .| ||| | | .|. ... . ..||. |||||||||.|... . ..... |. .... .. .
.....................iqylhipipDhgvpdllehflefvefieeald..ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielv
RTQRPaMVQTEDQYQLCYRAALEY
| .|| .|....|.. .|. .|..
rerRp.ivpnpgqlrqLyefelrl
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1402-1619 | 2.6e-38 | 126.8 | In-house | 2-167 (178) | alignment | ||
Range on Protein: 1402-1619
Range on HMM: 2-167/178.0
YDHSRVILTSIDGVPGSDYINANYIDGYrkqnAYIATQGPlpetmGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTetcgliqvtlldtvela
.|..||.|... |...||||||..|... |.....| |......|. ..|..| | ..|||.||| .
ldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................
tytvrtfalhksgssekrelRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERmkhekTVDIYGHVTCMRSQ
|.... .||||||. . .|.|.. .... . . || .|||||||||.|...... |... .... . .|..
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RNyMVQTEDQYVFIHEAL
|. .|....|. ...|
Rp.ivpnpgqlrqLyefe
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1417-1620 | 3.8e-38 | 125.8 | In-house | 2-150 (151) | alignment | ||
Range on Protein: 1417-1620
Range on HMM: 2-150/151.0
GSDYINANYIDGYrkqnaYIATQGPLPetmgDFWRMVWEQRTATVVMMTRLEEKSrvKCDQYWPARGtetcgliqvtlldtvelatytvrtfalhksgss
|||||..|..|. .....|||. ||.....|. |.|... .|| .| .|.|. |
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
ekRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAcnpLDAGPMVVHCSAGVGRTGCFIVIDAMLERmkhektVDIYGHVTCMRSQRNYMVQTEDQYVFIH
.|....... |||.|.|... .|.||. . . . ||..||||||.||||...... ||.. |... . .|..| ..||...|..|..
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
EALL
|||
fall
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1387-1622 | 4.7e-38 | 125.8 | In-house | 32-269 (285) | alignment | ||
Range on Protein: 1387-1622
Range on HMM: 32-269/285.0
LEVNKPKNRYANVIAYDHSRVILTSIDgvpgSDYINANYIDGY-RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE
| | ||||.| . . .||.| | ||| |... . |..||.||||||||. |||.|..... | |.|. | | || |.| . |
yeanpdlnryadvrcieetrvvlknhd....rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
T--CGLIQVTLLDTVELATY----TVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAgPMVVHCSAGVGRTGCFIVIDAM
| ..|| . | | | . ||| . . | |||. || |.. . . || || . |..|||||||||| |. ||
vvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkek.picvhcsagvgrtatfvgidya
LERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
|. . ... | ||. | ||. |..|.. |.|
tirimenpniemldivremramrfqavqshmqflflyvvlmey
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1673-1913 | 1e-37 | 124.3 | In-house | 31-268 (281) | alignment | ||
Range on Protein: 1673-1913
Range on HMM: 31-268/281.0
SANLPCNKFKNRLVNIMPYELTRVCLQP-IRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAE
| | |. ||| .|| ...|| |. . . .||| | .. .. || |||| |. |||||.|. |.| |||| .. | |||| .|.| .
vfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprn
RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKtkeqfgQDGPITVHCSAGVGRTGVFITLSIVL
. |. . | . | .. . .|..| | .. . .||. ||.. | .. . ... . | .||||||||.| .... | |
ahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira......rstppvihcsagvgrsgtlmaveial
ERMRYE-GVVDMFQTVKTLR-TQRPAMVQTEDQYQLCYRAALEY
. .. . |. | | || | | | ||| .|| | .. |..
qsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1390-1621 | 1.6e-37 | 123.9 | In-house | 48-285 (305) | alignment | ||
Range on Protein: 1390-1621
Range on HMM: 48-285/305.0
NKPKNRYANVIAYDHSRVILtsiDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCG-
.. |||| .| |. || | .| .|| |||. . . .| || || .| ||| | .... .. |. | || || .|.... ..
eagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlef
-----LIQVTLLDTVEL-----ATYTVRTFALHKSGS-SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACnpldAGPMVVHCSAGVGRTGCFIVID
|.| . .|.| | .|. | |. ...| .. .. ||| ||| . || .| . .. ||.|||||||.|||| ....
eekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarps....kgpivvhcsagigrtgsvvmle
AMLERMKHEKTVDIYGH-VTCMRSQRNYMVQTEDQYVFIHEALLE
.|... . .. . . .| ||| .||..||.|.|. .|.
yildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
PTPc_DSPc_SM00012 | 1809-1912 | 8.7e-37 | 120.9 | In-house | 1-105 (105) | alignment | |||
Range on Protein: 1809-1912
Range on HMM: 1-105/105.0
TIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYE-GVVDMFQTVKTLRTQRPAMVQTEDQYQLCY
|......|.||..|||.... ..... .|.| |.. .. .|. |||||||||||.|..|.|.|.....| . ||.||.|| ||.||| |||||.||. .|
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
RAALE
|| ||
ralle
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1681-1916 | 6.7e-36 | 118.4 | In-house | 58-285 (290) | alignment | ||
Range on Protein: 1681-1916
Range on HMM: 58-285/290.0
FKNRLVNIMPYELTRVCLQpiRGVEGsDYINASFLDGYRqqKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARY--QY
||| ... . ||| |. | .| ||. | ...| . .| |||.|.... |.|||. ... . |||| .| | |. ||.||.| .
kknrykdvvcndktrvilk..dGydG.dyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
F-VVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTkeqfgqDGPITVHCSAGVGRTGVFITLSIVLERMRYE
. |. . . . . |.. . | | .|.. .. .. ||.. |... .. . . |. ||..||||||.|||| |... . |. .
itvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka......sGpvvvhcsaGiGrtGtfvaievglqilldG
GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGS
.|. ..|..|| | . || . || . .. |.. .
keldlldlvralrnsrlnsvqvdiqylalveilldlGkd
|
|||||||||
PTPc_DSPc_SM00012 | 1521-1621 | 6.8e-36 | 118.0 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 1521-1621
Range on HMM: 2-105/105.0
LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA--GPMVVHCSAGVGRTGCFIVIDAMLERMKHE-KTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE
........||||||||....|| .|| || .. . .|.||||||||||||.|...| .|.....| |.|||. | .|.||. |||||.||.|...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
ALLE
||||
alle
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1390-1551 | 2.3e-34 | 113.6 | In-house | 33-196 (297) | alignment | ||
Range on Protein: 1390-1551
Range on HMM: 33-196/297.0
NKPKNRYANVIAYDHSRVILTsiDGVPGSDYINANYIDGY--RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR--GTE
|||| ...|.| .|| | .....|||||.|. .. || .|||| .|. |||..|.|| ..||...|.| | || ||| .
slrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerl
TCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC
..| . | | .. .| |. ||.| .| ||..||||||| . | .| .|
kagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcsc
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1390-1550 | 5.8e-34 | 112.2 | In-house | 28-192 (319) | alignment | ||
Range on Protein: 1390-1550
Range on HMM: 28-192/319.0
NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR----GT
|.|.|..||. ..||.| .| . . |..|.|. ||.. .| |||.| .| .. ||||.||||.. ..| .| | |. .| .|.|.. .|
skdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnt
ETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFmAWPDHGVPEYPTPILAFLRRVKA
.. | |.||| . | . |. |.. .| ||| . . |.. .|| .....| | .|..
slyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1679-1914 | 1.7e-33 | 110.5 | In-house | 55-289 (305) | alignment | ||
Range on Protein: 1679-1914
Range on HMM: 55-289/305.0
NKFKNRLVNIMPYELTRVCLQPIRgveGSDYINASFLDGY-RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQ
.. ||| .. ... | |. |||| | .. .| .|..|||| .. ..|| |. ... |||| | |.|. || ||||| . . .
aitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
---YFVVDPMAEyNMPQYILREFKVTD----ARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHktkeqfGQDGPITVHCSAGVGRTGVFITLSIV
||. .. . | | ..| .|. ..|..|.|.||..||| .... . | || ||||||.|||| ... .
lksgivvenvsg.skpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair......gskvpivvhcsagigrtgtivaieyi
LERMRYE-GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||.. . . | . ||.|| || .|.. || .| |.|.
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1390-1637 | 8.8e-33 | 108.6 | In-house | 43-284 (288) | alignment | ||
Range on Protein: 1390-1637
Range on HMM: 43-284/288.0
NKPKNRYANVIAYDHSRVILTsidgVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGL
| ..|| |. | .|| |. ||.|| . . .. | .| || |.. .|.|. |. .||...| || . | ..|.| . |. .
nptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekari
IQV---TLLDTVELAtYTVRTFALHKSGSSEKRE-LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpldaGPMVVHCSAGVGRTGCFIVIDAMLERMKH
.. . . ... .|. |. | |.. ... . |.|.|||| . | .| ..|... |.|||.|||||||| .|.| .|| ..
grlctvvkkkradid.klvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslq....kPivvhssaGvGrtgtlililialeslrl
EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCgHTEVPARNLYA
. . | .. .| .| .||| ||...| .|| . .. |....
ddflgirsllaklreerfkaiqtemqylyvhrcvleelll.kkykvlredfv
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1710-1903 | 2.3e-32 | 106.9 | In-house | 78-270 (301) | alignment | ||
Range on Protein: 1710-1903
Range on HMM: 78-270/301.0
INASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQ--YFVVD-PMAEYNMP-QYILREFKVTDAR-D
| | ... . . .||||||| ...|||| || .. ||||.. .| |||..| | . | . . | . |. . . . |...|.|. .
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
GQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgqdgPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQY
..||. .|...|...||||. |.. | |... || ||||||.||. ||. .. .. . ... ...| || .| |||. |
fatrtvthyqysewtdrgvPkshaelfdlmelvkksek......PivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1384-1614 | 5.5e-31 | 102.4 | In-house | 44-272 (301) | alignment | ||
Range on Protein: 1384-1614
Range on HMM: 44-272/301.0
NSNLEVNKPKNRYANVIAYDHSRViLTSIDGV--PgsdyINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPA
.|. ..| |.|| .| .. | || | | ||.|. . . .|||||||..|. ||| |. ..||... || ||..| |
esyaylpkdkhryptvPckPstav.evivdGkrvP....ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpv
RGTETCGL--IQVTLLDTVELA--TYTVRTFALHK-SGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpldaGPMVVHCSAGVGRTGCFIVI
. .|. . .... .. . . ||. .. .| . | . .|.. |.|.|||. . . .. || . |.|||||||.||. .||
kisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkkse....kPivvhcsaGiGrsvafigt
DAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVF
. . ... ..|... . .| .| |||. | .
eylareveadptieltealkhlrehrwngvqtnsqlyw
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1679-1914 | 4.4e-30 | 99.6 | In-house | 35-270 (285) | alignment | ||
Range on Protein: 1679-1914
Range on HMM: 35-270/285.0
NKFKNRLVNIMPYELTRVCLQPirgvEGSDYINASFLD-GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERS----
| || .. | ||| |. ||| ||.. ..| .||.||||| |. |||.|... . . ..|| | | | ||| |.| .
npdlnryadvrcieetrvvlkn....hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvk
-ARYQYFVvDPMAEYNMPQYILREFKVTDARDGQSRTI--RQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgQDGPITVHCSAGVGRTGVFITLSIV
.|. . | . || . |... | | . . | ||.| |. .|.. |.| . .. || |||||||||| |. .
fgkyeitl.teckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnp...kekpicvhcsagvgrtatfvgidya
LERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|. . ..|.. |. .|. | ||. |. . | .||.
tirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1669-1914 | 2.6e-29 | 97.2 | In-house | 33-271 (288) | alignment | ||
Range on Protein: 1669-1914
Range on HMM: 33-271/288.0
SRFISANLPCNKFKNRLVNIMPYELTRVCLQpirgVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYW
| | . | ..| |. ..||| |. . ||.| . . .. | .| || | .|.|| | . ||||..| | |.|| .|.
sidiidsfianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyf
PAER--SARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT-IRQFQFTDWPEQGVPKTGEGFIDFIGQVhktkeqFGQDGPITVHCSAGVGRTGVFI
| . .||.. . . ... . ... . . |. . ... . .|...|||. .. .. . . || ||.|||||||| .|
PsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl......kslqkPivvhssaGvGrtgtli
TLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|.|| .| . . . . .. || .| .||| || .| ||.|
lilialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1680-1914 | 8.3e-29 | 95.3 | In-house | 49-287 (305) | alignment | ||
Range on Protein: 1680-1914
Range on HMM: 49-287/305.0
KFKNRLVNIMPYELTRVCLQPirgVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYF
. ||| .. . || |.. .|| | .. . | .| || || .. ||| | .... | || .| | | .||..|.... ..
agknrykdvgcldnnrvkleg...pwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefe
------VVDPMAEYNMP------QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqfgqdGPITVHCSAGVGRTGVFITL
.| . .. . . | . ...| . .. . |||..||| . .... . .| |||.||||||.|||| . |
ekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpsk......gpivvhcsagigrtgsvvml
SIVLERMRYEGVVDM-FQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.|... ... . .. .| || .||..|| . .. |.|.
eyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1517-1642 | 3e-28 | 93.3 | In-house | 87-213 (440) | alignment | ||
Range on Protein: 1517-1642
Range on HMM: 87-213/440.0
EKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC-NPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
| | |.|... .|||.|||.. |.| ... |. . . ||..||||||.|||| |..|..| |. .||. . .||..| |||| .||.|.
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafv
HEALLEAATCGHTEVPARNLYAHIQKL
|||.||. || | . .. .....
heavlegllcgdtliledditerveqi
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1391-1622 | 4e-28 | 93.0 | In-house | 44-275 (312) | alignment | ||
Range on Protein: 1391-1622
Range on HMM: 44-275/312.0
KPKNRYANVIAYDHSRVILTSIDGVpgsdYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR--------
| ||| |. .| | |. . || ||.. | . ...||||| .| ||... ........ . | . || .|
kdlnrypniqcwdrgrftlagdenf....yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdled
---GTETCGLIQVTLLDtVELATYTVRTFALHKSGSSEKreLRQFQFMAWPDHGVPEYPTPILAFLRRVKAcnplDAGPMVVHCSAGVGRTGCFIVIDAM
|| | |.. . |. | .. .| | | ..|. .|||||.|. | .| || | |.. |||||||||| ...|..|
hrvyteycteieiggks.kdkithrvlkvvvkatgqesk..lnhyqwaswpdhgmpdscdtalrllsavkk....dkkpviahcsagvgrtgtlaliesm
LERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
. ..| . .. .| .| |.. |||. ..||
iaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlef
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1384-1619 | 4.1e-28 | 92.9 | In-house | 34-266 (307) | alignment | ||
Range on Protein: 1384-1619
Range on HMM: 34-266/307.0
NSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKsrVKCDQYWPARG
.. . |. | | | | ||| | | |.| ||...| | .| .| || .|. ||||||.... .||.| | .|. |||
taasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkae
TETC----GLIQVTLLDTVELATYTVRTFALHKS-GSSEKRELRQFQFmAWPDHGVPEYPTPILAFLRRVkacnpldAGPMVVHCSAGVGRTGCFIVIDA
... | .... |. . | | |. | |.| | .| . . .| .| ||.. . |.||.. || ...... |.
sdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg.dvnnssdvysplrvlrklrnl.......skpvvvqdilGvskaatlvaiei
MLERMKHEKT--VDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL
| . . . | .| .|.. |.. .|.|.. .
allsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1677-1841 | 1.6e-27 | 91.1 | In-house | 26-194 (319) | alignment | ||
Range on Protein: 1677-1841
Range on HMM: 26-194/319.0
PCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQK-AYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERS--
. | |.|..|..| ||| || | . . |..||.. ||.. . |||.| .| .|. ||||..|| .| .|| ||.| | | ..| .|.|.. .
vtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
--ARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFtDWPEQGVPKTGEGFIDFIGQVHKTK
| . | .|.. . . . .|| . . . .|.| .|| . .| . .|...
ntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrssl
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1493-1620 | 3.3e-27 | 90.3 | In-house | 18-140 (145) | alignment | ||
Range on Protein: 1493-1620
Range on HMM: 18-140/145.0
TLLDTVELATYTVRT-FALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDaGPMVVHCSAGVGRTGCFIVIDAMLErmkhEKtVDI
| || .|. . ..| . | . ..|. |.... |||||||. . .|.||. .... . . ||..|||||||||||...... ||. .. |..
taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll....lg.vsl
YGHVTCMRSQRNYMVQTEDQYVFIHEALL
. . .|||| ..|....|. |..|..|
eealelvrsqrpgavpnpgqlrflyefel
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1719-1908 | 3.5e-27 | 89.9 | In-house | 2-198 (199) | alignment | ||
Range on Protein: 1719-1908
Range on HMM: 2-198/199.0
RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSAR--YQYFVVDPMAEYNMPQYILREFKVTDAR--DGQSRTIRQFQ
. |. ||||| || |. |||.|.|| | |||. . |||. |. | . | . |.| . . .|. .| | ..|
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
FTDWPEQGVPKTG--EGFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVLERM--RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYR
|| | |. |. ||. .| | || .| |. |||| | | ||||..| | . |||.|. | || | .. . ..|.. |.
ftswkekttpnvalfvgfvvasrevskkyeq.ekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1720-1908 | 4.5e-27 | 89.5 | In-house | 2-197 (198) | alignment | ||
Range on Protein: 1720-1908
Range on HMM: 2-197/198.0
QQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSAR--YQYFVVDPMAEYNMPQYILREFKVTDAR--DGQSRTIRQFQF
|. ||||| || |. |||.|.|| | |||. . |||. |. | . | . |.| . . .|. .| | ..||
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
TDWPEQGVPKTG--EGFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVLERM--RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYR
| | |. |. ||. .| | || .| |. |||| | | ||||..| | . |||.|. | || | .. . ..|.. |.
tswkekttpnvalfvgfvvasrevskkyeq.ekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1500-1617 | 1.9e-26 | 87.9 | In-house | 28-139 (144) | alignment | ||
Range on Protein: 1500-1617
Range on HMM: 28-139/144.0
LATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDaGPMVVHCSAGVGRTGCFIVIDAMLermkHEKtVDIYGHVTCMR
| .|| ... . ...|| |.... |||||||.... .|.||. .... . . ||..|||||||||||...... |. ... .... . .|
lgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvr
SQRNYMVQTEDQYVFIHE
|.| ..|....|. |..|
srrpgavpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1679-1911 | 6.6e-25 | 82.3 | In-house | 52-287 (310) | alignment | ||
Range on Protein: 1679-1911
Range on HMM: 52-287/310.0
NKFKNRLVNIMPYELTRVCLQpIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-SARYQ
. ||| ... . .|| |. | ||| | .. ....| .|||| . |||||... . |..| | | || || |||. . |
ymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetyg
YFVVDPMAEYNMpQYILREFKVTDA-----RDGQSRTIR-----QFQFTDWPEQGVPKTGegfIDFIGQVHKTkeQfGQDGPITVHCSAGVGRTGVFITL
| ..| .. . .. || | | .. .. .||..||| . | . | . || ||||||..|..| ..|
cirvtnlsesse.efeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdek...chtvpqrlla..q.vrhgpcvvhcsagkdrlyvvval
SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAAL
. ..... ||. . . |. .| .||| || . | .
klkidkldrglkvdaeevktellksraiciqtelqyliidrvri
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1392-1485 | 1.5e-24 | 81.4 | In-house | 49-156 (350) | alignment | ||
Range on Protein: 1392-1485
Range on HMM: 49-156/350.0
PKNRYANVIAYDHSRVILT----SID----GVPGSDYINANYIDGY---RKQN---AYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQ
|||| |.. |.||||.| | | . ..|||||||. ..| |||||.|||.|. ||.... . ....| . | . ||..
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPARGTE
||. . .
YWqegsyd
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1794-1913 | 2.4e-24 | 81.0 | In-house | 36-142 (145) | alignment | ||
Range on Protein: 1794-1913
Range on HMM: 36-142/145.0
LrefkvTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfgqDGPITVHCSAGVGRTGVFItlsiVLERMRYEGvVDMFQTVKTLRTQR
| |. ... .|.. |.....|| ||| | ...|. .... .. .||. |||||||||||... .. |...| |....... .|.||
l.....tselellerlgiqylylpwpDhgvpdllellleflefieealke...ggpvlVHCsaGvgRtgtlv....aaylmlllg.vsleealelvrsqr
PAMVQTEDQYQLCYRAALEY
| .|....|.. .|.. ||.
pgavpnpgqlrflyefelel
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1681-1770 | 1e-22 | 75.3 | In-house | 49-152 (350) | alignment | ||
Range on Protein: 1681-1770
Range on HMM: 49-152/350.0
FKNRLVNIMPYELTRVCLQ----P----IRGVEGSDYINASFLDGY----RQQKA--YIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQ
||| .||.||| .|| |. . ....|||||..| ... |||||.|| . .||.... . . ..|..||.. |...|||..
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPA
||.
YWqe
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1651-1911 | 1.2e-22 | 75.0 | In-house | 13-267 (307) | alignment | ||
Range on Protein: 1651-1911
Range on HMM: 13-267/307.0
VTAMELEFKLLASSKAHTSRFISANlPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTII
| .| ...| | . | .|. |. | | . . .|| |. || |.| | ..| .| .| || .. .|||||... . |
vqelerrlevleesvdeislttaas.dnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyi
VMLTKLREMgrEKCHQYWPAERSARYQY----FVVDPMAEYNMPQYIlreFKVTDARD-GQSrtiRQFQFTDWPEQGVPKTGEGFIDFigQVHKTKEQFg
|||| .| |.|. ||| | .. . .. . .. .. . |.|| . | .. .| . . | .... . . .| . .
vmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadpl...frvtklklvGgd...deerflehwqgdvnnssdvyspl..rvlrklrnl.
qDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVV--DMFQTVKTLRTQRPAMVQTEDQYQLCYRAAL
|. |.. || ........ | | . .. . ..|. || .|. |.. .| . || |
.skpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1806-1915 | 1.7e-22 | 74.4 | In-house | 87-195 (440) | alignment | ||
Range on Protein: 1806-1915
Range on HMM: 87-195/440.0
QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQL
.|||..|... ||..|||| . .| .| ...|. | .||. ||||||.||||| |.. .| . .|.| ....| .|| |||| .|| .
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekag.ngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
CYRAALEYLG
. | || |
vheavlegll
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1796-1908 | 2e-22 | 74.9 | In-house | 48-139 (144) | alignment | ||
Range on Protein: 1796-1908
Range on HMM: 48-139/144.0
EfkvtdardgqsrtIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgQDGPITVHCSAGVGRTGVFITLSivleRMRYEGvVDMFQTVKTLRTQRPA
| . |.....|| ||| | ...|. ... | ..||. |||||||||||..... .|...| ........ .|..||
e.............giqylhlpwpDhgvpdllellleflefieeale...eggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpg
MVQTEDQYQLCYR
.|....|.. ...
avpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1431-1616 | 2.7e-22 | 74.1 | In-house | 33-214 (255) | alignment | ||
Range on Protein: 1431-1616
Range on HMM: 33-214/255.0
KQNAYIAtqgplpeTMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS--SEKRELRQFQFMA
..| |. |. |.... ..| .|||.. ..|....||..|.| | | .|.. | | .|| . . . .... ...
rknlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykG
WPDHGVPEYPTPILAFLRRVKacnplDAGPMVVHCSAGVGRTGCFIVIDAMLE----RMKHEKTVDI--YGHVTCMRSQRNYMVQTEDQYVFIH
|... || . || |. |. |. ..|||||.|.||. |.... . .. .||.. .. .||.|. ..| | |
WieknaPelareilnilkvvr.....dsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsi
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1431-1616 | 5.9e-22 | 72.8 | In-house | 3-197 (199) | alignment | ||
Range on Protein: 1431-1616
Range on HMM: 3-197/199.0
KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVELATYTVRTFALHKSG--SSEKRELRQFQF
| ||||| || ||| |||.|||| . .||. . . . |||. || | . || . . ||. .. | .. ||. ..||
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
MAWPDHGVPEYPT---PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKT--VDIYGHVTCMRSQRNYMVQTEDQYVFIH
.| .. |. ..| | . |..|||| | | || |. .| . . || ||.. .| | .. . ..| ||.
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1432-1616 | 1.3e-21 | 71.7 | In-house | 3-196 (198) | alignment | ||
Range on Protein: 1432-1616
Range on HMM: 3-196/198.0
QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVELATYTVRTFALHKSG--SSEKRELRQFQFM
| ||||| || ||. |||.|||| . .||. . . . |||. || | . || . . ||. .. | .. ||. ..||
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
AWPDHGVPEYPT---PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKT--VDIYGHVTCMRSQRNYMVQTEDQYVFIH
.| .. |. ..| | . |..|||| | | || |. .| . . || ||.. .| | .. . ..| ||.
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1559-1626 | 2.1e-21 | 70.1 | In-house | 1-68 (69) | alignment | ||
Range on Protein: 1559-1626
Range on HMM: 1-68/69.0
MVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCG
||||||.| |||| || | . |.| || |||. | || | || | .|.|||.|| || |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1682-1920 | 2.1e-21 | 70.9 | In-house | 46-282 (312) | alignment | ||
Range on Protein: 1682-1920
Range on HMM: 46-282/312.0
KNRLVNIMPYELTRVCLQpirGVEgSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA-------ERSA
|| || .. | | | | || | |. . . ...||||| ... ||.. || |..|. . | | ||| .| |
lnrypniqcwdrgrftla...gde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhr
RYQYFVVD-PMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgqdgPITVHCSAGVGRTGVFITLSIVLER
| .. . . . | .|| || . ..|.. ||..|.| . . .. |.| | |. |||||||||| .. . ..
vyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk......pviahcsagvgrtgtlaliesmiaa
MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHY
.|. .. .. || .| |.. || . |. ||.| | |
lrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1560-1626 | 2.2e-20 | 66.8 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 1560-1626
Range on HMM: 1-67/69.0
VVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCG
|||||.| |||| || | . |.| || |||. | || | || |..|.|||.|| || |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1389-1621 | 4.3e-19 | 63.2 | In-house | 46-277 (303) | alignment | ||
Range on Protein: 1389-1621
Range on HMM: 46-277/303.0
VNKPKNRYANVIAYDHSRVILTSidgvpgSDYINANYIDGYRKQNAyIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE---
| |||...|| |||.| |. | || |.|.. ...| | || ||. | |||.|. ||. |... | .. | .|
knmdknrfvdvicldhskvklsd......ssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkf
TCGLIQVTLLDTVELATYTVRTfALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPI-LAFLRRVKAC--NPLDAGPMVVHCSAGVGRTGCFIVIDAM-LE
|.| . |||. | | | . | | .. ||| .| .| . . .... . |. | | .|.||.| | .... |
eersirvgefkrvelgdgwvlk.vlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahls
RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
. . ..|. . .| | . || |. ... | |
lhseqasldlvkclenvrngrlhavqnlsqfsvvytllae
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1438-1615 | 5.7e-19 | 62.7 | In-house | 96-280 (302) | alignment | ||
Range on Protein: 1438-1615
Range on HMM: 96-280/302.0
TQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTL--LDT-VELATYT------VRTFAL--HKSGSSEKRELRQFQF
| .|. .| .. . ..| || .. . |. || .|. . .. . . |. .. .|. .| . | . .| . |. . ..|
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
MAWPDHGVPEYPTPILAFLrrvKACNPLDAGpMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
|||||| |. . . | | | |. ..||||||||||| .. | .. ...|. |. |. .|. | ||.|.| ...
sawpdhGapkeaytaldil...kfcesykkn.vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
I-set | Immunoglobulin I-set domain | 33-124 | 6.4e-19 | 59.5 | Pfam-A | 1-90 (90) | alignment | ||
Range on Protein: 33-124
Range on HMM: 1-90/90.0
PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDgAGSVLRIQPLRVqRDEAIYECTATNSLGEINTSAKLSV
|.| . ..|.. | ... |...|||.|...|.|.|....|.. ..... | . |.|. .| .|| .|.|.||||.|. ...|.|.|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtvee.aeytLtIsnvev.sDeGkYtckatnsagkaeakaeLkV
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1431-1616 | 5e-18 | 60.0 | In-house | 36-220 (263) | alignment | ||
Range on Protein: 1431-1616
Range on HMM: 36-220/263.0
KQNAYIAtqgpLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS--SEKRELRQFQFMA
..| |. | .|. |.... ..| .|||.. .|....||..|.| | | .|.. | ..| | . . . ........
rknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykg
WPDHGVPEYPTPILAFLRRVKACNpldagPMVVHCSAGVGRTGCFIVIDAM----LERMKHEKTVDI--YGHVTCMRSQRNYMVQTEDQYVFIH
|... || . || |. .. ..|||||.|.||. | |.. . . .. .||.. .. .||.|. ..| | |
Wiekndpelareilnilkvarnsk.....slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsi
|
|||||||||
fn3 | Fibronectin type III domain | 325-405 | 1.3e-17 | 56.9 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 325-405
Range on HMM: 2-85/85.0
PPIDLVVTETTATSVTLTWDSG--NSEPVTYYGIQYRAAGTEGPFQEVDGVATT-RYSIGGLSPFSEYAFRVLAVNSIGRGPPS
.| .| |.|.|.||.||.|. ...|.|.| ..|| .|.... .|.. .|| .. . || | .|| ||| ||| | ||.|
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1682-1913 | 1.6e-17 | 57.9 | In-house | 54-284 (302) | alignment | ||
Range on Protein: 1682-1913
Range on HMM: 54-284/302.0
KNRLVNIMPYELTRVCLQpirgVEGSDYINASFLDGYRQQKAYIATQGPLAEST---EDFWRMLWEHNSTIIVMLTKLREMGReKCHQYWP--AERSARY
||. .. .. ..| |. | .|.||| .. .. | .| | .|. |.|||| .... . .|.| . |. . ....| .. |
knqsedvpildsnlvkle....aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykey
QYFVVDPMA-EYNMPQYilREFKVTDARDGQSRTI--RQFQFTDWPEQGVPKTGEGFIDFIGQVhkTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLER
. . | |. . .. . .| | .. .| |... ||. | . .| ... | .. . |.|| |.|.|| ...|.
gkmfvNnrkVekaeeek..tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv..fakkikadentvivSknGaGRagafltlavavek
MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
. . . . ..||..|.|||..|.. .|| |.|.| |
lqkgkepnikeivksiRsqRpravdslkQyvslyiallly
|
|||||||||
fn3 | Fibronectin type III domain | 923-1004 | 2.4e-17 | 56.0 | Pfam-A | 3-85 (85) | alignment | ||
Range on Protein: 923-1004
Range on HMM: 3-85/85.0
PQNLHVTGLTTSTTELAWDPPVlaERNGRIISYTVVFRDINSQQ-ELQN-ITTDT-RFTLTGLKPDTTYDIKVRAWTSKGSGPLS
|.||.|.. |... .| |.|| ...| | .|.| .|. .... . . .. .| ..|||||||.|.| ..|.| . .| || |
PenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
fn3 | Fibronectin type III domain | 613-700 | 4.4e-17 | 55.2 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 613-700
Range on HMM: 2-85/85.0
PPQKVMCVSMGSTTVRVSWVPPPadSRNGVITQYSVAYEAVDGEDrgRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPES
.|. . . ...||....|| ||. ...| || |.| |. ..|.. .. ..| ..| | ||. |||...|.|....| ||||
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge..ewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1716-1903 | 5.9e-17 | 56.1 | In-house | 84-277 (302) | alignment | ||
Range on Protein: 1716-1903
Range on HMM: 84-277/302.0
DGYRQQKAYI-ATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA--RYQYFVV-DPMAEYNMPQYI--------LREFKVTDAR
|| ... | ...| .| .. ..| .|.| |... | . .|| .|. . ... . | . .. .. |.| . .
dGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkk
DGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIgqvhKTKEQFGQDgpITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQY
. . .|. ..|. ||. | || . .| . | | . .. . ||||||||||| .... .. . | |. . |. .|. | ||.|.|
kkvkktvdilafsawpdhGapkeaytaldil....kfcesykkn..vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqql
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1734-1900 | 9.3e-17 | 55.9 | In-house | 40-207 (255) | alignment | ||
Range on Protein: 1734-1900
Range on HMM: 40-207/255.0
STEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARD--GQSRTIRQFQFTDWPEQGVPKTGEGFI
. . |.... ... .|||. . | |.|||..|.| |. . .. |. . .. . .|| ..| . .|.. .... |.|. |. .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
DFIGQVHKTKeqfgqdgPITVHCSAGVGRTGVFITLSIVLERMR------YEGVVDMFQTVKTLRTQRPAMVQTE
. |...| .. ||||.|.||. |. .| .| . .| . .. || .|.. ..|
nilkvvrdsk.......svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtP
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1387-1620 | 1.3e-16 | 55.0 | In-house | 48-282 (302) | alignment | ||
Range on Protein: 1387-1620
Range on HMM: 48-282/302.0
LEVNKPKNRYANVIAYDHSRVILTSIDgvpgSDYINANYIDGYRKQNAYIATQGPLPETM---GDFWRMVWEQRTATVVMMTRLEEKSRvKCDQYWP--A
| ||. .| ..|. .|.|. .|.|| .. .. | .| | .. .|||||.... ..||.. . || .. ....| .
fkknlkknqsedvpildsnlvkleaep....dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks
RGTETCGLIQVTLLDtVELATYTVRTFAL--HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAM
.. | . | || | .. ... | |. . |... ||. . . . | | . ..|. |.|| | |.. .
gdykeygkmfvNnrk.VekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlava
LERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALL
.|.....| . | |. .|||| .|.. .|||... |||
veklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
fn3 | Fibronectin type III domain | 518-596 | 2.6e-16 | 52.7 | Pfam-A | 2-83 (85) | alignment | ||
Range on Protein: 518-596
Range on HMM: 2-83/85.0
QPADFQAEVESDTRIQLSWLLPP--QERIIMYELVYWAAEDED-QQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGV
.| ..... ..| ..||| |. .. | ||. |. ..... ... . .|.|.||..|||.| |.|...|... | |
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegp
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1346-1440 | 3.4e-16 | 53.2 | In-house | 4-95 (95) | alignment | ||
Range on Protein: 1346-1440
Range on HMM: 4-95/95.0
PIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDgvpGSDYINANYIDGYRKQNAYIATQG
|| .. . . ...| .| .|. || .. | | ||||. |.. || .||.||. |||||| ..||| ..|.|||.||
pihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlttkr...dsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1388-1618 | 5.4e-16 | 53.6 | In-house | 17-254 (290) | alignment | ||
Range on Protein: 1388-1618
Range on HMM: 17-254/290.0
EVNKPKNRYANVIAyDHSRVILTSIDGVPGSDYINANYIDgYRKQNAYIATQGPLPET-------MGDFWRMVWEQRTATVVMMTRLEEKSRV----KCD
. .. ..|... .. ..||.| .||| ||.. . . . |.|| |. .. . .|| |. . . |||. ||||. |
kkhemdqRlevpLv.eatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCa
QYWPARGTET--CGLIQVTLLDTVELATYTVRTFALhKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKaCNpldAGPMVVHCSAGVGRTGCFI
.| | . | . ..| . .. .|. . | . |. . .. | . |.| . .|. .. || .. |..||| |. | ..
kYvpesvgeelkfkgltvkCkskekeddvetRelvv.kfddeeeftvtHsllkgWnklnvqedtktllsliqkvk.as...ktpvivHcvdGiSrsAala
VIDAMLERMK-HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEA
|. . .. | . . .|.||. ..... .. |. .
aiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdag
|
|||||||||
fn3 | Fibronectin type III domain | 715-813 | 8e-16 | 51.1 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 715-813
Range on HMM: 2-85/85.0
PPRKVEVEPLNSTAVHVYWKLPVpsKQHGQIRGYQVTYVRLENGEprglpiiqdvmlaEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARS
.|. . |.. .|| ... |. | ...|.| ||.|.| ..|| | ... .. .. |..||.| |.|...|.|....| | .|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge.............ewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1846-1913 | 8.1e-16 | 52.6 | In-house | 246-314 (319) | alignment | ||
Range on Protein: 1846-1913
Range on HMM: 246-314/319.0
QDGPITVHCSAGVGRTGVFITLSIVLERMRYE-GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
. ||..|||| ||||||. |. | .... ||. |.| .| .| |.| .||.. |. . ||
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1555-1621 | 9.3e-16 | 52.4 | In-house | 246-313 (319) | alignment | ||
Range on Protein: 1555-1621
Range on HMM: 246-313/319.0
DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHE-KTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
. ||.||||| |||||| | | ...... ..||| | .| .| |.| .|| ||. | |
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlse
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1392-1480 | 2e-15 | 50.9 | In-house | 50-154 (349) | alignment | ||
Range on Protein: 1392-1480
Range on HMM: 50-154/349.0
PKNRYANVIAYDHSRVILT--------------SIDGVPGSDYINANYIDGY--RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKC
|||| ... |.||||.| |. |||||||. .. ||||| ||| |. ||.... .. |. .. .|.| ||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
DQYWP
|.||
diywq
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1516-1620 | 3.5e-15 | 50.6 | In-house | 212-341 (350) | alignment | ||
Range on Protein: 1516-1620
Range on HMM: 212-341/350.0
SEKRELRQFQFMAWPDHGVPEYPTPILAFLR-------RVKACNPL---DAGPMVVHCSAGVGRTGCFIVIDAMLE----------RMKH----EKTVD-
|. .. |.|. |.| .. | || | | . | . |..||||||||||| .. .| .|. .... || |
sdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl
IYGHVTCMRSQRNYMVQTEDQYVFIHEALL
| | .|.|| |||. ||..||.||||
isiivnelrkqrismvqnldqfifiYeall
|
|||||||||
fn3 | Fibronectin type III domain | 419-504 | 3.6e-15 | 49.0 | Pfam-A | 1-85 (85) | alignment | ||
Range on Protein: 419-504
Range on HMM: 1-85/85.0
SPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPpnAWHKHNTDAGL-LTTVGSLLPGITYSLRVLAFTAVGDGPPS
|.|...... ..... ..|.||....| . ||.| | ... .|. .... |. | || .|..|| | ...| ||.|
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekggge..ewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1810-1913 | 3.9e-15 | 50.4 | In-house | 217-343 (350) | alignment | ||
Range on Protein: 1810-1913
Range on HMM: 217-343/350.0
IRQFQFTDWPEQGVPKTGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLE----------RMR----YEGVVD-MFQTV
. |.|. |.. .. | .. . . .. . . || |||||||||||...|| .|. ..| . | ....|
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv
KTLRTQRPAMVQTEDQYQLCYRAALEY
. || || |||. ||. .| |.| |
nelrkqrismvqnldqfifiYeallfy
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1672-1771 | 5.5e-15 | 49.6 | In-house | 89-181 (244) | alignment | ||
Range on Protein: 1672-1771
Range on HMM: 89-181/244.0
ISANLPCNKFKNRLVNIMPYELTRVCLQpiRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREmgrekCHQYWPAE
| | | .||| .|... || | .| | ||||||. . || || |||... |||.|. | ..|.| . | .|||
kdafnpnnswknregaglpfdfnrvpls..kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee.....edeywpds
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1390-1513 | 7.3e-15 | 49.3 | In-house | 34-158 (332) | alignment | ||
Range on Protein: 1390-1513
Range on HMM: 34-158/332.0
NKPKNRYANVIAYDHSRVILTSIDGVpgSDYINANYIDGYRKQNAYIATQGPLPE-TMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCG
| || . ..||||| |. || |. ||...||| |..||| .| |. . | ||||| |.. . .... ..|| . |. || |
nmdmnriphlycfdhsrvelapqdgk..ddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrkapydisdrgfeksf
LIQV--TLLDTVELATYTVRTFALHKS
| .. |. .|| . .| | |.
lhefgaksleecelkakicrkfwpekr
|
|||||||||
I-set | Immunoglobulin I-set domain | 135-216 | 7.9e-15 | 46.4 | Pfam-A | 1-82 (90) | alignment | ||
Range on Protein: 135-216
Range on HMM: 1-82/90.0
PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPatsNGRIKQLRSG---ALQIESSEESDQGKYECVATNSAGTR
|... .. .|.. .... | . |.|.|..||.|| .. . . |.| .. | |.. |.||.|||.|.||||||..
pkftqklkdvevseGesvelectveGepepsvsWakdgselks...sqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagka
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1394-1549 | 3.7e-14 | 46.9 | In-house | 56-208 (332) | alignment | ||
Range on Protein: 1394-1549
Range on HMM: 56-208/332.0
NrYANVIAYDHSRVILTSIDGVPgSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCGLIQ
| ... ||. | ||| . |||| .. . || | . . . ||.|| ||.. ..|.. |. | |.|.| .. | ..
n.vvkivpydrylvrltssqlnr.lGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGild
VTLLDTVELATYTVRTFALHKSgsSEKRELRQFQFMAWPDHGVPEYPtPILAFLRRVK
|. . |. . . .| . |.| | .. ... | . .| | ||. . .|
verkefvkrniletrllelskG..nethrvlhykvfGwtettlpkye.dflalrkvmk
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1682-1904 | 3.9e-14 | 47.5 | In-house | 22-249 (290) | alignment | ||
Range on Protein: 1682-1904
Range on HMM: 22-249/290.0
KNRLVNIMpYELTRVCLQPIRGVEGSDYINASFLDgYRQQKAYIATQGPLAES-------TEDFWRMLWEHNSTIIVMLTKLREMGRE----KCHQYWPA
..|| . . | ||| |. .||| |... . . . |.|| |... |.|| | . ... .||| . | .. | .| |
dqRlevpL.veatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpe
ERS--ARYQYFVVDPMAEYNMPQYILREFKVTdARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqfgqdGPITVHCSAGVGRTGVFITLS
. ... . | . . . || |. |.. |. .. .| . |... ... | .|.. | |. ||| |. | .. ..
svgeelkfkgltvkCkskekeddvetRelvvk.fddeeeftvtHsllkgWnklnvqedtktllsliqkvkask......tpvivHcvdGiSrsAalaaii
IVLERMR-YEGVVDMFQTVKTLRTQRPAMVQTEDQYQ
. . .| | . . .|.|| || ..... ..
lgyQkiaetsgsvkledvlkalrkqralaitsalela
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1547-1621 | 4.9e-14 | 46.9 | In-house | 220-293 (297) | alignment | ||
Range on Protein: 1547-1621
Range on HMM: 220-293/297.0
RVKACNPLDAgPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
..| | .| ...|||||||||.| . |..|....... |. .. .|.|| .||| .|. ....| |.
slraemprna.yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
fn3 | Fibronectin type III domain | 836-906 | 6.2e-14 | 45.1 | Pfam-A | 12-83 (85) | alignment | ||
Range on Protein: 836-906
Range on HMM: 12-83/85.0
AMNTALLQWHPPKELPGELLGYRLQYCRADEAR-PNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGE
... |.| |||. |.. ||...|. ... . ..... .. ...|.||| ||.| ||..| |.|| |.
tstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegp
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1852-1913 | 8.7e-14 | 45.6 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 1852-1913
Range on HMM: 2-63/69.0
VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
||||.| |||| ||.. . . |.. | .||.| |. .| || || |..| . . | |
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1851-1912 | 9.4e-14 | 45.6 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 1851-1912
Range on HMM: 2-63/69.0
TVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
||||.| |||| ||.. . . |.. | .||.| |. .| || || | .| . . | |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalve
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1731-1899 | 1e-13 | 45.8 | In-house | 43-212 (263) | alignment | ||
Range on Protein: 1731-1899
Range on HMM: 43-212/263.0
LAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARD--GQSRTIRQFQFTDWPEQGVPKTGE
| . . |.... ... .|||. | |.||| .|.| |. . .. |. . . . .|. ... . . .|....... |.|. |. .
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelar
GFIDFIGQVHKTKEqfgqdgpITVHCSAGVGRTGVFITLSIVLERMR------YEGVVDMFQTVKTLRTQRPAMVQT
. . . . |. . ||||.|.||. | .| .| . .| . .. || .|.. ..|
eilnilkvarnsks.......lvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraiht
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1346-1428 | 2.1e-13 | 44.4 | In-house | 5-85 (440) | alignment | ||
Range on Protein: 1346-1428
Range on HMM: 5-85/440.0
PIPITDLADNIERLKAndGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDG
|| ..|.|| .. . | .|. . | . . ..| || |||| |..|||||||.| . ||| |||||| ||.|
piivadfadyvqnnrr..srafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1427-1508 | 6.2e-13 | 42.9 | In-house | 230-309 (440) | alignment | ||
Range on Protein: 1427-1508
Range on HMM: 230-309/440.0
DGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSrvkCDQYWPARGT-ETCGLIQVTLLDTVELATYTVRTF
.|| |.||.|||| || |. ||||.| . | .|..|. .|..|. | ||| | | . | . .. |||.
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndkt...csiywpvntrsvtfgpftvghkgsenmnrvkvrtl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1657-1729 | 6.3e-13 | 42.7 | In-house | 28-95 (95) | alignment | ||
Range on Protein: 1657-1729
Range on HMM: 28-95/95.0
EFKLL--ASSKAHTSRFISANLPcnkfKNRLVNIMPYELTRVCLQPIRgveGSDYINASFLDGYRQQKAYIATQG
||| . .| ..| ||.| |||..||.||. |||.| | |||||| |.||| ....|||.||
efksismtsgapytvgsseanip....knrflnifpydatrvvlttkr...dsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1682-1833 | 9.1e-13 | 42.3 | In-house | 55-203 (332) | alignment | ||
Range on Protein: 1682-1833
Range on HMM: 55-203/332.0
KNrLVNIMPYELTRVCLQPIRgVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVV
.| .|.|.||. | | . . . ||||| .. . || | . . ||.|. | .| ||.| . |.. || .|.| . ... ..
rn.vvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGil
DPMA-EYnMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTgEGFIDF
| |. . . ||. .. . .. . ... | | .|| | |. .
dverkef.vkrniletrllelskGnethrvlhykvfGwtettlpky.edflal
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1679-1910 | 1.7e-12 | 41.6 | In-house | 47-275 (303) | alignment | ||
Range on Protein: 1679-1910
Range on HMM: 47-275/303.0
NKFKNRLVNIMPYELTRVCLQpirgveGSDYINASFLDGYRQQKAyIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA-RYQ
| |||.|... . ..| | | || ||.|. ..|| | || ||. .. |||.|. | . ...| |. . . .| .. ...
nmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkfe
--YFVVDPMAEYNMPQyiLREFKVTDARDGQSRT-IRQFQFTDWPEQGVPKTG-EGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLER
. | . . .. . .|| .|. .. . .. .|| . .| | |. | |. .. . | .|.||.| | .
ersirvgefkrvelgd..gwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahls
MR-YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAA
. . .|. . ....| | || |. . |
lhseqasldlvkclenvrngrlhavqnlsqfsvvytll
|
|||||||||
I-set | Immunoglobulin I-set domain | 236-319 | 2.1e-11 | 35.4 | Pfam-A | 1-90 (90) | alignment | ||
Range on Protein: 236-319
Range on HMM: 1-90/90.0
PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNV----LELSNVVRS--ANYTCVAISSLGMIEATAQVTV
|.|.......||. | ||.|.| . | | | |.|. . .||...... | . |..||| .| .|||.| |.| ||.|...|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1682-1769 | 4.3e-11 | 36.7 | In-house | 51-154 (349) | alignment | ||
Range on Protein: 1682-1769
Range on HMM: 51-154/349.0
KNRLVNIMPYELTRVCL----QPIRGVEGS----------DYINASFLDG--YRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCH
||| .|.||| .|| | .. .... | ||||| .| . .| ||||| || . .||.... . ... |.. | . |||.
knrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcd
QYWP
.||
iywq
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1385-1464 | 7.1e-11 | 36.2 | In-house | 32-116 (347) | alignment | ||
Range on Protein: 1385-1464
Range on HMM: 32-116/347.0
SNLEVNKPKNRYANVIAYDHSRVILTSIDG-----VPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM
.. | . ||| .| | .||.|. . . |||| .| .. || || |||.|. |||.|| . . || .
vewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1690-1822 | 1.6e-10 | 35.4 | In-house | 4-125 (130) | alignment | ||
Range on Protein: 1690-1822
Range on HMM: 4-125/130.0
PYELTRVClqpirgveGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREmgrekCHQYWPAERSAR-YQYFVVDPMAEYN
..|..|. | .||||||. . . |. || |||... |||.|. | ..|.| . | .||| |. .. ... .
efevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsvee.....edeywpdsePlewyeediivtltdrd
MPQYILREF-KVTDARDGQSRTIRQFQFTDWPEQG
..| .. .. . ... || ..|| .|
efknikasnleiesdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1679-1763 | 1.9e-10 | 34.7 | In-house | 34-117 (332) | alignment | ||
Range on Protein: 1679-1763
Range on HMM: 34-117/332.0
NKFKNRLVNIMPYELTRVCLQPIRGVEgsDYINASFLDGYRQQKAYIATQGPLAESTED-FWRMLWEHNSTIIVMLTKLREMGREK
| ||. . .. .|| | | | . |. |||..||| .. ||| .| |. . || ||||. |.. ..|... . | . |
nmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1843-1914 | 2.7e-10 | 34.1 | In-house | 261-344 (349) | alignment | ||
Range on Protein: 1843-1914
Range on HMM: 261-344/349.0
QFGQDGPITVHCSAGVGRTGVFITLSIVLE--R--------MRYEGVV-D-MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
. | .. |||||| |||||..|| ..|. . .. . | .. .| .|| || .||| |. .| | |.|.
dtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyf
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1653-1718 | 3.8e-10 | 33.7 | In-house | 23-86 (440) | alignment | ||
Range on Protein: 1653-1718
Range on HMM: 23-86/440.0
AMELEFKLLASSKAHTSRFisANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGY
|.| |. || |. .. | |.|| || ||| ||. |. .|| |. ..|| |||||||...|
afedewsllpsglsqpsdi..aslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1716-1795 | 5.7e-10 | 33.1 | In-house | 230-307 (440) | alignment | ||
Range on Protein: 1716-1795
Range on HMM: 230-307/440.0
DGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREmgrEKCHQYWPAE-RSARYQYFVVDPMAEYNMPQYILR
.|| ...|.|||| || . ||||.. ... . |.|| .| . | ||| . || . | | || . .|
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfgpftvghkgsenmnrvkvr
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1375-1430 | 1.6e-09 | 31.8 | In-house | 24-78 (244) | alignment | ||
Range on Protein: 1375-1430
Range on HMM: 24-78/244.0
DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDgVPGSDYINANYIDGYR
| ..| |. | .| |||| |.. .|..||||.| ||||||||||.| .
dhtreflqtnavlsanatknryinilpfdetrvilsssk.kegsdyinanyiqgsq
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1838-1907 | 2e-09 | 32.1 | In-house | 105-169 (182) | alignment | ||
Range on Protein: 1838-1907
Range on HMM: 105-169/182.0
HKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVlermrYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCY
| .. |.| ..||| || ||||| |. .| | .. ...|..| .|| .|| .| .|.
vkvvafalqegkvavhChaGlGrtGvliacylv.....yakrltaekaiklvrskrpksiqtreqvelvk
|
|||||||||
Ig_2 | Immunoglobulin domain | 142-223 | 2.1e-09 | 29.3 | Pfam-A | 8-78 (80) | alignment | ||
Range on Protein: 142-223
Range on HMM: 8-78/80.0
QlKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNgrikqlrsgaLQIESSEESDQGKYECVATNSAGTRYSAPANL
. ||.. . |. |.| |||.|...| || .... ... | | . ...|.|.|.|.|.|| | | . ..
p.tvvtegenvtLtCqapgnptpkvqwykdgeelsqsqna..........lfipnvsaedsGtYtCrasnsegskqsnsvev
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1518-1621 | 2.2e-09 | 31.1 | In-house | 217-342 (349) | alignment | ||
Range on Protein: 1518-1621
Range on HMM: 217-342/349.0
KRELRQFQFMAWPDHGVPEYPTPILAFLRrVK--------ACNPL---DAGPMVVHCSAGVGRTGCFIVIDAMLE--RMKHE---------KTVD-IYGH
|| |.|. |.| .. | || | || | . | . ...|||||| |||| .. .| .|. . .. .. | |.
PyellqlqvknwldlslllnPisilqale.vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisii
VTCMRSQRNYMVQTEDQYVFIHEALLE
| .| || ||| |...|.||||.
vnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1412-1533 | 2.8e-09 | 31.4 | In-house | 7-125 (130) | alignment | ||
Range on Protein: 1412-1533
Range on HMM: 7-125/130.0
IDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKsrvkcDQYWPARGTET--CGLIQVTLLDTVELATYTVRTFA
.. ..| .||||... . . |. || || .| |||.|. |. .|.. .||. |.||| | ||| | | .
vsrlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdrdefknikasnle
LHKSGSSEKRELRQFQFMAWPDHG
.. .. | || || |
iesdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1673-1772 | 5.6e-09 | 29.1 | In-house | 21-88 (169) | alignment | ||
Range on Protein: 1673-1772
Range on HMM: 21-88/169.0
SANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINAsfldgyrqqkayiatqgplaestedfwRMLWEHNSTIIVMLTKLremgrEKCHQYWPAER
|.| ||. ||| . ||| || . ||||||| ||.|| |...||.| . ..||
maeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdt.....ddknnfwpeke
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1818-1909 | 5.9e-09 | 31.3 | In-house | 85-172 (194) | alignment | ||
Range on Protein: 1818-1909
Range on HMM: 85-172/194.0
W--PEQGVPKTGEGFIDFIGQVHKTKEQfGQDGPITVHCSAGVGRTGVFITLSIVL-ERMryegvvDMFQTVKTLRTQRPAMVQTEDQYQLCYRA
. |..|.. . | .|. |.. .. ..| . ||| ||.||||... .. .| .. . ....| || .... |... ..
lpfpddgtvPsleillrfldlvdeflne.dpggvvaVHCkaGlgRtGtlvaaYLiyrlgm......saeeAialfrekRpgaipnqdyleallkr
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1672-1771 | 6.4e-09 | 28.9 | In-house | 19-86 (169) | alignment | ||
Range on Protein: 1672-1771
Range on HMM: 19-86/169.0
ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINAsfldgyrqqkayiatqgplaestedfwRMLWEHNSTIIVMLTKLremgrEKCHQYWPAE
. |.| ||. ||| . ||| || . ||||||| ||.|| |...||.| . ..||
fmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdt.....ddknnfwpek
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1524-1617 | 4.5e-08 | 27.7 | In-house | 85-170 (182) | alignment | ||
Range on Protein: 1524-1617
Range on HMM: 85-170/182.0
FQFMAWPDHGVPEYpTPILAFLRRVKacNPLDAGPMVVHCSAGVGRTGCFIVIDAMlermkHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE
. ..|.|.||. . || . |. |. | . ||| || |||| | . . | .. .. .||.| .|| .| ...|
vynfgwkDygvasl.eriLdivkvva..falqegkvavhChaGlGrtGvliacylv.....yakrltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1527-1610 | 7.1e-08 | 27.8 | In-house | 85-164 (194) | alignment | ||
Range on Protein: 1527-1610
Range on HMM: 85-164/194.0
MAWPDHGVPEYPTPILAFLRRVKACNPLDA-GPMVVHCSAGVGRTGCFIVIDAMLeRMKHeKTVDIYGHVTCMRsqrNYMVQTED
. .||.|.. .| ||. |. . |. | .||| ||.||||.... . |.. . . ..... .| . .... |
lpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiy.rlgm.saeeAialfrekR...pgaipnqd
|
|||||||||
Ig_2 | Immunoglobulin domain | 49-124 | 7.5e-08 | 24.3 | Pfam-A | 16-80 (80) | alignment | ||
Range on Protein: 49-124
Range on HMM: 16-80/80.0
VASFVCQATGEPKPRITWMKKGKKVSSQRFEviefddgagsvlRIQPLRVQRDEAIYECTATN-SLGEINTSAKLSV
. |||.| |.|...| |.|...|... . ..|. | .|.|.|.| .... ..| .. |
nvtLtCqapgnptpkvqwykdgeelsqsqna............lfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
|||||||||
Ig_2 | Immunoglobulin domain | 240-319 | 8.9e-08 | 24.1 | Pfam-A | 4-80 (80) | alignment | ||
Range on Protein: 240-319
Range on HMM: 4-80/80.0
IPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTkedempVGRN--VLELSNVVRSANYTCVAIS-SLGMIEATAQVTV
. .....| | .|.||| | | | | |.| . |||. ..| . . .. | .|||.| .... . .|||
lsapptvvtegenvtLtCqapgnptpkvqwykdgeels......qsqnalfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1433-1534 | 1.1e-07 | 25.7 | In-house | 137-235 (244) | alignment | ||
Range on Protein: 1433-1534
Range on HMM: 137-235/244.0
NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKsrvkcDQYWPARGT-ET-CGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWP
|| || || .| |||.|. |. .|.. .||. |.||| | | ||| | |. . . .. | || ||
aeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdseplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwp
DHGV
|
sdgt
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1385-1481 | 1.6e-07 | 24.4 | In-house | 22-86 (169) | alignment | ||
Range on Protein: 1385-1481
Range on HMM: 22-86/169.0
SNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINAnyidgyrkqnayiatqgplpetmgdfwRMVWEQRTATVVMMTRLEEKSrvkcdQYWPA
..| .|. ||| | .| | || | . ||||||| ||.|| .. .|.. ..| ..||
aeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddkn.....nfwpe
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1669-1753 | 2.5e-07 | 24.5 | In-house | 27-116 (347) | alignment | ||
Range on Protein: 1669-1753
Range on HMM: 27-116/347.0
SRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEG-----SDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
|.| |.. . ||| . . ||| | | . . ||||| . .| || || || .. |||.|. . | .| .
skftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1385-1481 | 2.6e-07 | 23.6 | In-house | 21-85 (169) | alignment | ||
Range on Protein: 1385-1481
Range on HMM: 21-85/169.0
SNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINAnyidgyrkqnayiatqgplpetmgdfwRMVWEQRTATVVMMTRLEEKSrvkcdQYWPA
..| .|. ||| | .| | || | . ||||||| ||.|| .. .|.. ..| ..||
aeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddkn.....nfwpe
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1544-1622 | 3.5e-07 | 23.9 | In-house | 226-304 (332) | alignment | ||
Range on Protein: 1544-1622
Range on HMM: 226-304/332.0
FLRRVKACNPLDAgPmVVHCSAGVGRTGCFIVIDAMLeRMKHEKTVDIY---GHVTCMRSQRNYMVQTEDQYVFIHEALLEA
.|.. . | | | .. .. | |.| |.||| .. |. .| . | . ..|.|.. | .. |. ||.|..|.
tlkkyihtppsfa.p.iiqsarGsaraGvfvvidlli.rlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy
|
|||||||||
Ig_3 | Immunoglobulin domain | 148-211 | 1.5e-06 | 20.4 | Pfam-A | 17-75 (75) | alignment | ||
Range on Protein: 148-211
Range on HMM: 17-75/75.0
KartATMLCAAGGNP-DPEISWFkdfLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATN
. | | | |.| | ||| .| .. ... .. | |.| ..| | |.|||.|
n...vtLtCsaeggpppptisWy...ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
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subfamily_PRL_pd | Subfamily PRL | 1839-1885 | 2.5e-06 | 21.6 | In-house | 82-128 (151) | alignment | ||
Range on Protein: 1839-1885
Range on HMM: 82-128/151.0
KTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
|.| . . ..||| ||.||. |...|... . |.|| |.. ..
kekfkeepkstvavhcvaGlGraPvlvalalieaGmkyedavefire
|
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Ig_3 | Immunoglobulin domain | 38-111 | 4.6e-06 | 18.8 | Pfam-A | 6-75 (75) | alignment | ||
Range on Protein: 38-111
Range on HMM: 6-75/75.0
VPEDQTGLSGGVASFVCQATGEP-KPRITWMkkgkKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAiYECTATN
|. .| ||| .. |.|.| | .|.|.|. . .. .. | .. .|.| | . . . |.|.|.|
vspsptvtsggnvtLtCsaeggpppptisWy....ietppelqgsegssssestLtissvtsedsGt.YtCvasN
|
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PTPc_motif_SM00404 | 1803-1899 | 5.6e-06 | 21.3 | In-house | 42-127 (140) | alignment | |||
Range on Protein: 1803-1899
Range on HMM: 42-127/140.0
RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVhktkeqFGQDGPITVHCSAGVGRTGVFItlsiVLERMRYEGVvDMFQTVKTLRTQRPAMVQT
. ....| | . | .. . | . .||| .. . | . ||| ||| |.. .| . . |||... .. . .. .. .||.. ..
kensgfqilqiplddnekdklskyldkvldfiena......ekkggkvlVHCqaGvSRSatli....iaYlmryrql.slaeayefvkerRpiispn
|
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Ig_3 | Immunoglobulin domain | 236-304 | 5.9e-06 | 18.4 | Pfam-A | 2-73 (75) | alignment | ||
Range on Protein: 236-304
Range on HMM: 2-73/75.0
PRFSIPPSSQEVMPGGsVNLTCVAVGAP-MPYVKWM-MGAEELTKEDEMPVGRNVLELSNVV--RSANYTCVA
| |..||. .. |. |.||| |.| | | . |. . || . . . ..| .|.| | .|||||
Pvisvspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtissvtsedsGtYtCva
|
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subfamily_CDC14_pd | Subfamily CDC14 | 1847-1905 | 6.9e-06 | 20.1 | In-house | 263-316 (328) | alignment | ||
Range on Protein: 1847-1905
Range on HMM: 263-316/328.0
DGPITVHCSAGVGRTGVFITLSIVlERMRyegvVDMFQTVKTLRTQRPAMVQTEDQYQL
.| |.||| ||.|||| .|. .. .. | . ... || || .| . | |
eGaiavhCkaGLGrtGtLiacylm.khyr....ftaaeaiawlricrPGsvigpqqkfl
|