Gene SYNJ2 in Homo sapiens

Synonym: INPP5H, RP11-266C7.2, SYNJ2

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP111_AA protein Get Run
HsapP111_AA_183-485 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Synaptojanin_pd Subfamily Synaptojanin 56-811 0.0 1286.1 In-house 2-754 (754) alignment 
Range on Protein: 56-811
Range on HMM: 2-754/754.0
KLTDAYGCLGELRLKSGGTSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAKEEERLIALKKILSSGVFYFSWPNDGS-RFDLTVRTQKQGDDSS
|..||||.||.|||..|...||||||||||.|||.|.||||.|||.|....|..||..|.|.|.|||.|.||.||||. .|.. |.||....|.. ...|
kivdaygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrseasdedriielkkllasgtfyfsssadsasrldlslsaqrrkqees

EwGNSFFWNQLLHVPLRQHQVSCCDWLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMDDGVSSFVQIRGS
| .|.||||..||. |....|.|.|||||..||.|.||||||..|||||.|.||.||||.||||..|||||.|.|.|||||||.|..|| |.||||||||
e.dnrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirGs

VPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLLR
|||||||||||||||...|.||.||.|.|||||.  |||.||..|.||||||..|||||..|||| |.||.|| |.|...||.|| .|||| ||||.||.
vPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnllGskegeevlskafkkhlkasehakdvpfvkfdyhqkvkggkkeklekllk

PQLKLHWEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKP-IVDRFVESFKAMWSLNGHSLSKVFTGSRALEGKAK
.||||..|....|.. ..   . |.|.||.||||||||||.||....||||. ||..|.||||. .|.|| |.||..|| ||...||...|..|||||||
kqlklflesasfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealklsskesvvsrfeevfkslWsknGdeiskiyaGtgalegkak

VGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALLVTPRILKAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTA
|.||||||||..||||.||.|..|||||.|||.|..| ||.|||. .||.|..| ....|||...||..|.|..|..||..||||||||||.||..|...
vsklkdgarsvartiqnnfldsskqeaidllllgntyveeladkarallkssllrasakilkelvereqelteakklricvgtwnvnggkqlrsvalkne

ELTDWLLDSPQLSGATdsqdDSSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDT
.|||||||.|.||||.    ||.||||.|.||||.|.|.|.|.|.|||||.|.|.|.|||..||...|.||||.|||||||..||||..||||||||..|
sltdwlldlpelsgae....dskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvlsrdakyvlltseqlvGvclfvfvrpklvpfirdvavst

VKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEF
||||.||.|||||||.||...||||.|||||||.||||.||||||||.||..|..|||||...|||||||.|||||||||...|| ..||..|..||.|.
vktGlgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkkkdydklven

DQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKH
|||. ||..||.||.|.||...| ||||||. |..||||.|.|.|||||||||.|||.
dqltkqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwrrkkk
subfamily_INPP5F_pd Subfamily INPP5F 109-811 3e-186 612.3 In-house 117-806 (951) alignment 
Range on Protein: 109-811
Range on HMM: 117-806/951.0
EEAKEEER-LIALKKILSSGVFYFSWpndgsRFDLTVRTQKQGDDS-----SEWGNSFFWNQLLHVPLRQHQVSC-CDWLLKIICGVVTIRTVYASHKQA
|| |.|.| |  |||.||.| ||.|       ||||   ||.| ..      .| ..||||. |  .| . . .    .|. .| | | .....  ....
eeeklekrlleelkkllsdgsFYysl.....dfDltntlqkrgleeksestddwderFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkv

KACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMDDGVSSFVQIRGSVPLFWEQPGLQVGShHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVV
.  |.|| | .| ||||..||..|||.|.||||||..... . | ||.|||||||.||||.| .. . .... |  |.. ||||.|.  . ..||..|.|
sltlisrrSrkragtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvfweqsgkkykp.kikitrseeetqpaFdehfkeqlkkygkvviv

NLLGSRGGEEVLNRAFKKLLWASChAGDTPMINFDFHQFAKGGKLEKLETLLrPQLKLHWEDFDVFTKGENV-SPRFQKGTLRMNCLDCLDRTNTVQSFI
|||  .. |. | .|.|. | ..    |. .|.||||.  .| | |....|. ...| .  .. .| . ..      ||| .|.||||||||||.||. |
nllsqkssekklskaykeqllkle.skdvflikfdfheetsgekfenvskli.elikneikevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqai

ALEVLHLQLKTLGLSS--KPIV-DRFVESFKAMWSLNGHSLSKVFTGSRALEGKA-K------VGKLKDGARSMSRTIQSNFFDGVKQEAIKLllvgdVY
...||.|||. ||| .  ..|  ..... .|..|. ||  .|. ..|. || |.  .       | ||||  |.||  ..|| |  .|..| |     . 
skavlelqleklglfepessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidl.....ll

GEEVADKGGMLLDSTALLVTPRIlkamTERQSEFTNFKRIRIAMGTWNVNGGKQFrsnvlrtAELTDWLLDSpqlsgAtdsqdDSSPADIFAVGFEEMVE
|.  ...   | | .   .  ..     |.. .||... | . .|. ||||  ..       |.|  .| .      .     .   .|.. .| .|.||
Gklpkqevvelidpkkeekeeel....rekeekftetsninllvgsvnvngsskk.......adlskllfpi.....g.....ekfkpDlvvlGLqEvvE

LSAGNIVNASTTNKKMWGEQLQKAISRS---HRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLT
|.||.|..| .. .|.| ....... .    ..|..| | ||... | .|||  ..  ...| .||.|||.|| |||||||..||..  |||||. |||.
LtaGsiLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfeysatsFcfvnsHla

AGQSQVKERNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSA
||.| | || .|||||.... |. ....  ||..|| ||.||||||. |||   .  |...||||.|||. .  .|..|. |.| ...| ||||||.|. 
AGasnveeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqeidkLleyDqLtkeieaGevFegfkEetlkFrPtYkyDlgtk

AYDTSDKCRTPAWTDRVLWWRKKH
 ||||.| ||||||||...  . .
nYDtsekeRtPaWtDRiiykgevl
Sac_COG5329 41-810 7.6e-121 396.1 In-house 43-818 (1070) alignment 
Range on Protein: 41-810
Range on HMM: 43-818/1070.0
TLAPEEKEVIKGQYGKlTDAYGCLGELrlksGGTSLSFLVLVTGCTSV-GRIPDAEIYKITATDFYPLQEEAKEEERL----------------IALKKI
. . . ||... . ..    ||.|| .      . ..|| ..|| ..| ..||  .|||| | ||..|... ...|.                   ||| 
avselkkegfrslssa.heiygvlGli....elegslflivitgkskvaqvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkL

LSSGVFYFSWPndgsrFDLTVRTQKQ--GDDSSEWG---NSFFWNQLLHVPLR-----QHQVSC-----CDWLLKIICGVVTIRTVYASHKQAKACLVSR
|| | |||| .     ||.| . ||.  .  .. .    ..|.||. |   |       .. .      ...|  .|.| ..   .. . |..   |.||
lsngsFYfStd.....fditntLqkrlkeelelsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISR

VSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRG
.| .| |||| .|||.|||.|.||||||| .|  . . ||.|.|||.|.|||| . .  .  ..  | .||  .|||.|   | |.||....||||.  .
rSskragtRflarGvDddGnvanFVETEqIvyssqycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKs

GEEVLNRAFKKLLWAScHAGDTPMINFDFHQFAK---GGKLEKLETLLRPQLklhwEDFDVFT--KGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALE
 |  | ....| | .|    ..  . ||||. ..    ....||..|.. .|    ..|. |.    |  .  .|.| .| ||||||||||..|. |...
sEieLseryekhlkls.ekpkihlteFdfhketsqdgfddvkkLlplieqdl....lefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskr

VLHLQLKTLGLSSKPIVDRFVESFKAMWSLNGHSLSKVFTGSRALEGKA-------KVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVAd
||  |.. .. .|.   . |.......|. || ..|. .||. || ...        .|.|.|   |.|| .. ||.|. ||.||.|||    . | |  
vlleqfrsikvisaiddedflqklneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllLgklpdqeave.

kggmLLDSTALLVTPRilkaMTERQSEFTNFKRIRIAMGTWNVNGgkqfrsnVLRTAELTDWLLDSpqlsgaTDSQDDSSPADIFAVGFEEMVELSAGNI
    |.|.    |. |     ....|||| .| . |. .| |.||       ......|...||..      ..   ..   .. .. ...  ||.. ..
....lydpineyvnlr....lrkseseftaaknvsiftltfnsng.......essstkllklllkv......lekkisklvvgvvglqkqiwlelillss

VNASTTNKKMWGEQLQKAISRS-HRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKE
...| . ....   ..|  ...   ...  | || .. .  ...         .   . ||| ||...||||| |...   ..|.|  ... ... ...|
ltksefkeeeeenlvrkyenklkkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaeseglvfifvdasaaledenese

RNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLefDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKC
|| .|. ||... ....     |.  .. ...|..||.  |||   .. .. ..|   .... |.. .|.| .. .  ... ...... .   .||... 
rnskyesitkrvskeipkmikdhqlilldiainltidydeeevraekekeidrelk..kydtkqeltekvfvekvleptevpellekksyeddndtdted

RTPAWTDRVLWWRKK
. .....|.|  ...
ayrklrtrkliqkee
subfamily_SAC1_pd Subfamily SAC1 57-486 4.3e-91 296.8 In-house 4-451 (458) alignment 
Range on Protein: 57-486
Range on HMM: 4-451/458.0
LTDAYGCLGELRLKSGgtslSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAK--------EEER-LIALKKILSSGVFYFSWPNDGS-RFDLTVR-
 .. .|.|| ..|.||    ..|...|  ..||||    ||... ..  |.... .        ||.. |  |...|.|  ||||   | .  .. . . 
vvkiagilGiikLlsg....kylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekv

---TQKQGDDSSEWGNSFFWNQLLHVPLRQhQVSCCDWLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMD
   . |. .      . ||||. |   ||. . .  ...| .| | ..|...  ..|. |  |.|| |. |.|||...|||. .|.|.|||||||.. ..
tsaalkerslleradeRffwnkhlledlrk.epelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveae

DGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHrGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKlLWASCHAGDTPMINFDFHQFAK
  ..||||.|||.||.|.| .      ...|.   | .  ||..|.  ..|.||..|.|||.  .| |. |. |... .  . .. ..  . ||||.  .
kaltsFvqvRGsiPllWsqkpnLkykPkvkls.esedsldafkkhldeqielygenvlvnLvdqkGsEkklgeayes.vvralnkkkikyvafDFHkeCr

GGKLEKLETLLrPQLKLHWEDFDVFTKG-ENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGL--SSKPI--VDRFVESFKAMWSLNGHS
  . ..|..|.  ||. . .....|.|  |.   . ||| .| ||.||||||| ||| .| |||. ||..||.  . . .   ... .||| .|. |.  
kmrwdrlklLi.dqlekelsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnada

LSKVFTGSRALE------G-KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLV
.|. ..|  ||       | ....| |.||  |.|| .. || || .|..|.|.| 
vsvqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflg
Syja_N SacI homology domain 60-347 3.5e-78 253.9 Pfam-A 1-318 (319) alignment 
Range on Protein: 60-347
Range on HMM: 1-318/319.0
AYGCLGELRLKSggtsLSFLVLVTGCTSVGRIP-DAEIYKITATDFYPLQEEAKE---------------EERLIALKKILSSGVFYFSwPnDgsrFDLT
|||.|| .||.|     |.|...|....|..|  . .||||. ..|.||..|..|               |. |  |||.|||| ||||   |   .|||
aygilGlirlls....esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfS.y.d...yDlt

VRTQKQGDDSS--------------EWGNSFFWNQLLHVPLRQHQVSCCDWLLKIICGVVTIRTVYAS-HKQAKACLVSRVSCERTGTRFHTRGVNDDGH
 . |..  ...              |  . |.||. |. || . .... .||| .|.|.|..|... . .|... .|.|| |..| |||. .||..|||.
rslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGn

VSNFVETEQMIY-M-D--DGVSSFVQIRGSVPLFWEQ-PGLQvGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWA
|.|||||||...   .  . | ||||||||||||||| ..|.  ... ...|  ||. .||..|.  |...||..||||||...|.|. |..|...|. .
vANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelink

S----CHAGDTPMINFDFHQFAKGGKLE
      .  .  .|.||||.  || | |
lnkklkekkklkyiefDfhkeckgkkfe
Syja_N SacI homology domain 60-347 3.5e-78 253.9 In-house 1-318 (319) alignment 
Range on Protein: 60-347
Range on HMM: 1-318/319.0
AYGCLGELRLKSggtsLSFLVLVTGCTSVGRIP-DAEIYKITATDFYPLQEEAKE---------------EERLIALKKILSSGVFYFSwPnDgsrFDLT
|||.|| .||.|     |.|...|....|..|  . .||||. ..|.||..|..|               |. |  |||.|||| ||||   |   .|||
aygilGlirlls....esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfS.y.d...yDlt

VRTQKQGDDSS--------------EWGNSFFWNQLLHVPLRQHQVSCCDWLLKIICGVVTIRTVYAS-HKQAKACLVSRVSCERTGTRFHTRGVNDDGH
 . |..  ...              |  . |.||. |. || . .... .||| .|.|.|..|... . .|... .|.|| |..| |||. .||..|||.
rslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGn

VSNFVETEQMIY-M-D--DGVSSFVQIRGSVPLFWEQ-PGLQvGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWA
|.|||||||...   .  . | ||||||||||||||| ..|.  ... ...|  ||. .||..|.  |...||..||||||...|.|. |..|...|. .
vANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelink

S----CHAGDTPMINFDFHQFAKGGKLE
      .  .  .|.||||.  || | |
lnkklkekkklkyiefDfhkeckgkkfe
DUF1866 Domain of unknown function (DUF1866) 863-1008 1.7e-62 198.4 Pfam-A 1-146 (146) alignment 
Range on Protein: 863-1008
Range on HMM: 1-146/146.0
EVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVK
.||..|||..||..||.||...|||.|||.||.|.|....||..|.|.|..||.|.|.|.|...|||.....|||||.|..|||.||...|.||.|||.|
dveilevdpearravfkeviaaqGPpDativvslksgdedekeifdealieeLlqelaslGeviLvRfvedkmlvtFrdgesALevlslkgikvlgralk

IRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDY
||.|.||||| |.|||.........||.||||.||||.....| ||
irlKskdWlksleeEivlsttetisvsltanstlleedaslasady
subfamily_FIG4_pd Subfamily FIG4 46-485 1.4e-51 166.6 In-house 56-538 (569) alignment 
Range on Protein: 46-485
Range on HMM: 56-538/569.0
EKEVIKGQYGKLTDAYGCLGELRLKSGgtslSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAK------EEERLIAL-KKILSSGVFYFSWPNDGS
 .|  .  . | . ||| || .|. .|     .|.|||   .|. |    ||||  ... ...|. |      .|.|.  | |..  .  ||||.  | .
leeanrdglekkvsayGilGfvrfleg....yylilvtkrkkvaviGghaiykiedialikitedskksekssdearylklfkdvdltknfyfsysydlt

RF---DLT----VRTQKQGDD---------SSEWGNSFFWNQLLHVPLRQhQVSCCDWLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRG
|    .|.     |.... .|          ..  . | ||. |  ||.. .|.  ||||.|| | |.  ..    |. . .|..| | . .|.||  ||
rtlqtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkd.tvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrG

VNDDGHVSNFVETEQMI-------YMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQV-VVNLLGSR---GGEE
|| .|.|.| |||||..       . .| .|||||.||||||.|.|   .. .         .  | |  .|.  | ..||. . ..||. ..     |.
vnnkGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpikidvvdPfasaaalhfddlfqryGspiiilnlvkkkekrkres

VLNRAFKKLLWAS----CHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKlHWEDFDVFTKGENVSPR-FQKGTLRMNCLDCLDRTNTVQSFIALEVLH
.|...|.. .        .      |..|... .|  . . ||.| .   |   .   .|........   |.| .| ||.|||||||. |  |.   | 
illeefeaaieylneflPeekklkyiswdmaraskskeenvlevlekyaek.svkktGiflsapdlestkiqeGivrtnCvdcldrtnaaqfvigkvalg

LQLKTLGLSSKPIVD---RFVESFKAMWSLNGHSLSKVFTGSR---ALEGKAKVGKLKDGARSM----SRTIQSNFFDGVKQEAIKLLL
 |||.||.  .. ..     |. .. ..   |  |.  ..||.    ..   |. .... .| .    .| .   | |  ||.|| |.|
yqlkslGiidesklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlfl
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 535-855 7.5e-33 104.3 Pfam-A 1-249 (249) alignment 
Range on Protein: 535-855
Range on HMM: 1-249/249.0
GTWNVNGgKQFRSNV-LRTAELTDWLLDSPqlsgatdsqddsspADIFAvgFEEMVELsagN---IVNastTNKKMWG--EQLQKAISRSHRYIlltsaq
.||||.| .. ||.   ....| |.| .                .|. .  . |..|    .     .   |. ....      |. .. ...       
ltwNvlg.wnarsdrakkldqladllqsed..............pDvll..LQEvded...plsella...tglaselgldgdgksggggggda......

lVGVCLYIFVRPYHVPFIRDVAIDTVKTGMG---GKAGNKGAVGIRFQfhSTSFCFICSHLTAGQSQVK--ERnEDYKEItQ-KLCFPMGRnvfshdYVF
 .| .| ....  ..  ||..  ...|.| .   .  ||||.|..||.  .........|||.|... .  || ....|| .    .. |.      .|.
.gggglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaei.dkladdsrgs......pvi

WCGDFNYRIDLTYeevfyfvkrqdwkkllefdqlqlqkssgkifKDFHEGAINFGPTYKYDVGSAAY-------------DTSDKCRTPAWTDRVLWwrk
..||||.|.|...                               |.|.|.|..|.|....| |..|.             ||. |.|.||..|..|.   
laGDfNsrpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilv...

khpfdktagelnlldsdldvdtkvRHTWSPGALQYYGRAELQA-SDH
                        . .|.   . .... . .  |||
........................ssgwpalvvsgasllsdrggSDH
subfamily_INPP5F_pd Subfamily INPP5F 841-875 2.8e-06 16.7 In-house 808-842 (951) alignment 
Range on Protein: 841-875
Range on HMM: 808-842/951.0
ALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARE
 |.|| .||. .|||||| |.  ..|. ||   . 
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