Gene CTDSPL2 in Homo sapiens

Synonym: HSPC129, HSPC058, CTDSPL2

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily CTDSPL2
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP118_AA protein Get Run
HsapP118_AA_287-429 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CTDSPL2_pd Subfamily CTDSPL2 289-430 1.4e-83 270.0 In-house 1-142 (142) alignment 
Range on Protein: 289-430
Range on HMM: 1-142/142.0
SLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIK
|||||||||||||||..||.|.|||||||....||||||||||.||||||.|...|.|||||||||||||||..|||.|.|..|||||||||||.|||||
slvldldetlvhcslekleeatltfpvlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyik

DLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDN
||.||||||.||||.|||||||||||.|||||||||.|.||.
dlsilGrdlektiivdnspqafayqlenGipieswfedendk
NIF NLI interacting factor-like phosphatase 289-450 5.3e-57 184.1 Pfam-A 2-159 (159) alignment 
Range on Protein: 289-450
Range on HMM: 2-159/159.0
SLVLDLDETLVHCSLNELEdaALTF--PvlfqDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNY
 |||||||||||.. .. .     .  .    .  ....| .||. .|||...|..||...||||.| ||...|..|||||.|...||.||.|.. .|.|
tLVLDLDetLvhskekkdl..kedgkkv....eektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngky

IKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMD-KNDNELLKLIPFLEKLVELnEDVR
.|||..||||||...|.|.||..|. | .||||||....| ..|.|||||.||||.| .  .|||
vKdLsllgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpflealeks.ddvr
subfamily_SCP_pd Subfamily SCP 289-430 8.2e-52 166.8 In-house 2-142 (142) alignment 
Range on Protein: 289-430
Range on HMM: 2-142/142.0
SLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDpKKQLVRHRLFREHCVCVQGNYIK
.||.|||||||| |.. ...| .  ||  .....||||  ||.  |||.|.....|..|||||   ||| ....|| ||...|.|||||.||  .|||.|
clvidldetlvhssfkpvknadfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlld.kkkvlrarlfrescvfhkgnyvk

DLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDN
||. |||||.|.||.||||... .   | .|.|||| ||.|.
dlsrlgrdlkkviivdnspasyifhpenavpveswfddkedt
CPDc_SM00577 288-429 1.1e-45 147.2 In-house 3-145 (146) alignment 
Range on Protein: 288-429
Range on HMM: 3-145/146.0
FSLVLDLDETLVHCslN---------ELEDAALTFPvlfqdviYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREH
  |||||||||||.  .         | .. . ...        .|.| .||. .|||.......|...||...| |||..|..||||. | ...|.|..
kvLVlDLdetLvhs..anmaepksfsevsptdslae.......tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqd

CVCVQGNYIKD-LNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKND
|..|.|...|| |..| .||||..|||||....... .| ..|.... ...|
crlvkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_DULLARD_pd Subfamily DULLARD 290-430 5.6e-41 131.8 In-house 4-152 (153) alignment 
Range on Protein: 290-430
Range on HMM: 4-152/153.0
LVLDLDETLVHCSL--------NELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVC
|||||||||.|           ..     ..  || ...  ..||  ||.  .||...|. |....|||| ..||..... || .. ....|..|.||| 
lvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvl

VQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDN
 .|.|.||| ..  |||..||.||||.|.. .. |.|||.||. | .| 
esgkytkdlslvssdlssviilDnspvayrknpdnaipikswlsdpsdt
subfamily_TIM50_pd Subfamily TIM50 327-429 1.1e-26 85.5 In-house 24-125 (126) alignment 
Range on Protein: 327-429
Range on HMM: 24-125/126.0
RLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPkKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMD
. ||.   |||......||..||... ..| .|.. ||| |||...||||...  |.|. .|||. | ||||| |..|  ....  | .| . .. |  .
kkrPgvdafleqlaelfeivvftseqgltaaplidkldP.kqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkksvklqpenalalkkweGn

KND
..|
add
subfamily_FCP1_pd Subfamily FCP1 289-413 2.5e-21 68.3 In-house 3-133 (146) alignment 
Range on Protein: 289-413
Range on HMM: 3-133/146.0
SLVLDLDETLVHCSLN-ELEDAA------LTFPVlfQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLF-REHCV
 ||.|||.||.|.. . ..|  .       .| .  .      ||.|||  .||||..|..||. ..| ... ||... .||||.|.|  .|.. |. ..
vLvvDlDqtlihttkdptievkeekkkdikkftl..peekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdell

CVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ
  . .  |  ... .| |  .|||.  . . ..
dassktkklkklfptddsmvviiDDredvWnfa