Gene SCP2 in Homo sapiens

Synonym: OS4, PSR2, SCP2, CTDSP2

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily SCP
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP122_AA protein Get Run
HsapP122_AA_106-248 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_SCP_pd Subfamily SCP 109-249 6.1e-86 277.4 In-house 2-142 (142) alignment 
Range on Protein: 109-249
Range on HMM: 2-142/142.0
CVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKD
|.|||||||||||||||..||||.||.||.||.|||||||||.|||||.|.|||||.||||||||||||||.||||...|.||||||||||||.|.||||
clvidldetlvhssfkpvknadfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkd

LSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADT
||||||||.|..|.|||||||||||||||||.|||||..||
lsrlgrdlkkviivdnspasyifhpenavpveswfddkedt
NIF NLI interacting factor-like phosphatase 109-267 1.7e-52 169.5 Pfam-A 2-158 (159) alignment 
Range on Protein: 109-267
Range on HMM: 2-158/159.0
CVVIDLDETLVHSSFKPINNADFIVPieiEgTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDR-CGVFRARLFRESCVFHQGCYVK
..|.|||||||||..|. .. |.  .   | ......| |||..||||... . .| |.||||  .||.|| | ||.   .|..||.||||....| |||
tLVLDLDetLvhskekkdlkedgkkv...e.ektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvK

DLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDD-MADTELLNLIPIFEELSGAEDV
||| |||||....|.|.|| |. ..|.|..|......|   |||||.|.|..|.|. ..||
dLsllgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpflealeksddv
subfamily_CTDSPL2_pd Subfamily CTDSPL2 109-248 1.2e-49 159.9 In-house 1-141 (142) alignment 
Range on Protein: 109-248
Range on HMM: 1-141/142.0
CVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGV-FRARLFRESCVFHQGCYVK
..|.||||||||.| .....| .  |.. | .|.|||| .||.. |||.|. .||| .|||||   ||| . ||||     .. |||||.||. .| |.|
slvldldetlvhcslekleeatltfpvlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyik

DLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMAD
||| |||||.||.|.|||| .. .  || .|..|||.|  |
dlsilGrdlektiivdnspqafayqlenGipieswfedend
CPDc_SM00577 107-248 1.2e-46 150.3 In-house 2-145 (146) alignment 
Range on Protein: 107-248
Range on HMM: 2-145/146.0
RICVVIDLDETLVHS-------SFKPINNADFIVPieiegttHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRAR-LFRESC
. ..|.|||||||||       ||.. .. |....       ..|.||||||||||| .. .|||.|.||.. .||||.. ||||. . .  | |.|..|
kkvLVlDLdetLvhsanmaepksfsevsptdslae.......tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdc

VFHQGCYVKD-LSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMAD
....| ..|| || | .||.|..|.|||..|. ..||||.......... |
rlvkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_DULLARD_pd Subfamily DULLARD 110-249 4.9e-45 144.9 In-house 4-152 (153) alignment 
Range on Protein: 110-249
Range on HMM: 4-152/153.0
VVIDLDETLVHS--------SFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRC-GVFRARLFRESCVF
.|.||||||.||        . ||  . ||.| . |.... ..|| |||.||.|| .. . .. |.||||. .||..|.| ||.  |... |..|..|| 
lvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvl

HQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADT
..| |.|||| .  || ...|||||| .| ..|.||.|..||. |  ||
esgkytkdlslvssdlssviilDnspvayrknpdnaipikswlsdpsdt
subfamily_TIM50_pd Subfamily TIM50 145-248 2.7e-26 84.2 In-house 22-125 (126) alignment 
Range on Protein: 145-248
Range on HMM: 22-125/126.0
YVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFD
 . ||| || || ...|||| |.||.. . .| |. | ||  .. . ||||... . .|  ||||| | |||.| ...|  ..|. ..||||. .. |  
rfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkksvklqpenalalkkweG

DMAD
...|
nadd
subfamily_FCP1_pd Subfamily FCP1 108-229 9.2e-14 43.8 In-house 2-130 (146) alignment 
Range on Protein: 108-229
Range on HMM: 2-130/146.0
ICVVIDLDETLVHSSFKPI-----NNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCG-VFRARLFRESCVFH
...|.|||.||.|.. .|.     ..   |  ...  . .  || .||.. ||| .. .|.|  ..| .  .||. .. .||  . .|  |..    ...
lvLvvDlDqtlihttkdptievkeekkkdikkftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdelld

QGCYVKDLSRL-GRDLRKTLILDNSPASY
.   .|.|..|  .|    .|.|.  . .
assktkklkklfptddsmvviiDDredvW