Gene MreDSP-Un-1 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP009_AA protein Get Run
MbreP009_AA_500-602 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP3_pd Subfamily DSP3 534-602 3.7e-16 53.2 In-house 92-159 (162) alignment 
Range on Protein: 534-602
Range on HMM: 92-159/162.0
MLSRHDITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVaQPNRGFMQQLRTMEAALHQ
 ||...  ..|  ..| |||.|||. ||| ..|... . .|.|...| . .||.||..||....  |..
alsqkegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeelkr
0049772 (Phosphotyrosine protein) phosphatases II 546-601 1.1e-15 53.6 In-house 219-274 (314) alignment 
Range on Protein: 546-601
Range on HMM: 219-274/314.0
VAKGKSRSTT-LVMCYLMATQKLNVDDVLREVQRRRPvAQPNRGFMQQLRTMEAALH
 . ||.|..| .|..|||  ........|..|...|| ..||.||..||. .|  |.
CkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyefile
subfamily_DSP19_pd Subfamily DSP19 541-600 1.6e-15 51.7 In-house 91-150 (152) alignment 
Range on Protein: 541-600
Range on HMM: 91-150/152.0
TLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAAL
...|    | |||...|. |||....|.. . |..|.  || ..|| ||..||...|| |
avlvHCnAGvSRsasvviaylmkkeelsleealelvrearpcikPneGFikqLkeyeael
subfamily_DSP14_pd Subfamily DSP14 544-602 7.3e-15 49.3 In-house 88-146 (157) alignment 
Range on Protein: 544-602
Range on HMM: 88-146/157.0
VTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALHQ
|  . | ||| .|.. ||| ..||.  .  . |. .||. .|| || .||.. | .|..
vhCvaGvSRSAslclaylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkg
0044763 (Phosphotyrosine protein) phosphatases II 549-602 8e-15 50.4 In-house 120-172 (178) alignment 
Range on Protein: 549-602
Range on HMM: 120-172/178.0
GKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPvAQPNRGFMQQLRTMEAALHQ
|..||.|||..||| ...|........|..||| ..||.|...||. .|  |..
GvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllk
PTEN_1 548-602 2.5e-14 48.5 In-house 139-193 (196) alignment 
Range on Protein: 548-602
Range on HMM: 139-193/196.0
KGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALHQ
 |..|| |.|..|||...||..|. |. |...||.. || .....|.  .| |..
aGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaella
subfamily_DSP15_pd Subfamily DSP15 542-598 4.6e-14 46.8 In-house 81-137 (151) alignment 
Range on Protein: 542-598
Range on HMM: 81-137/151.0
LVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
 .|  . | |||.|||. |||.  .||  |.|. .. .| ||.|| || .||.  | 
vlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaRsvanPnfGfkrqlkeyek
subfamily_DSP12_pd Subfamily DSP12 538-599 1.4e-13 45.5 In-house 81-142 (155) alignment 
Range on Protein: 538-599
Range on HMM: 81-142/155.0
HDITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAA
.. ...|  . | ||| |.|. ||| ..||.... |. |.. .| ..|| ||..||.  |. 
eegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeiepNegFleQLklfekm
0048076 (Phosphotyrosine protein) phosphatases II 543-598 5e-13 44.4 In-house 85-140 (145) alignment 
Range on Protein: 543-598
Range on HMM: 85-140/145.0
VVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
.|    |..|..|||..||| .........|..|...|| | || |....|.  | 
lVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpgavpnpgqlrflyefel
subfamily_DSP1_pd Subfamily DSP1 544-600 5.4e-13 43.3 In-house 100-156 (163) alignment 
Range on Protein: 544-600
Range on HMM: 100-156/163.0
VTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAAL
.  . | |||.||.. ||| |.......    |..||.. .|| ||..|| . |  |
ihCqaGisRsstlclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkl
0048179 (Phosphotyrosine protein) phosphatases II 541-598 5.8e-13 44.3 In-house 85-142 (144) alignment 
Range on Protein: 541-598
Range on HMM: 85-142/144.0
TLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
  .|    |..|..|||..||| ...|.....|..|..||| | ||.|....|.  | 
pvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrpgavpnpgqlrfLleyek
0041856 (Phosphotyrosine protein) phosphatases II 548-601 7.2e-13 44.0 In-house 118-173 (182) alignment 
Range on Protein: 548-601
Range on HMM: 118-173/182.0
KGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRP--VAQPNRGFMQQLRTMEAALH
 |..|. |||..||| ............|..|||  | .|| .|. ||  .|  |.
aGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll
0043147 (Phosphotyrosine protein) phosphatases II 548-598 1.4e-12 43.2 In-house 109-158 (172) alignment 
Range on Protein: 548-598
Range on HMM: 109-158/172.0
KGKSRSTTLVMCYLMAtQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
 |..|. |||..|||  ..|........|...|| | .| .....|.  | 
aGvgRtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfek
PTPc_motif_SM00404 549-597 1.8e-12 42.3 In-house 90-138 (140) alignment 
Range on Protein: 549-597
Range on HMM: 90-138/140.0
GKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
| ||| ||...||| ...|....... |..|||  .|| .|..||  .|
GvSRSatliiaYlmryrqlslaeayefvkerRpiispnlnfvrqLieye
DSPc Dual specificity phosphatase, catalytic domain 547-597 2.7e-12 41.7 Pfam-A 81-131 (133) alignment 
Range on Protein: 547-597
Range on HMM: 81-131/133.0
AKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
. | ||| ||...||| |..|.... .. |..||.   || ||..||. .|
qaGisRSatliiaYlmktknlslneAyefvkerrskispnagflrqLleye
DSPc Dual specificity phosphatase, catalytic domain 547-597 2.7e-12 41.7 In-house 81-131 (133) alignment 
Range on Protein: 547-597
Range on HMM: 81-131/133.0
AKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
. | ||| ||...||| |..|.... .. |..||.   || ||..||. .|
qaGisRSatliiaYlmktknlslneAyefvkerrskispnagflrqLleye
0045098 (Phosphotyrosine protein) phosphatases II 508-599 4.4e-12 41.5 In-house 163-270 (278) alignment 
Range on Protein: 508-599
Range on HMM: 163-270/278.0
PIPIGLVPSDAPGPLFLGGMRAVNQSML------------SRHDITLVVTVAKGKSRSTTLVMCYLMATQ---KLNVDDVLREVQRRRPV-AQPNRGFMQ
|.| . |||.     ||  .. ... .               .. . .|    |..|. |||..||| ..   .........|....||  |..| ....
pwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyr

QLRTMEAA
.|  ... 
flyeflle
0042113 (Phosphotyrosine protein) phosphatases II 521-597 4.4e-12 41.4 In-house 158-239 (245) alignment 
Range on Protein: 521-597
Range on HMM: 158-239/245.0
PLFLGGMRAVNQSMLSRHDITLVVTVAKGKSRSTTLVMCYLM-----ATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
 |.|  ...|.. . .  . ...|    |..|. |....|||     ............|....|| | .. .....|. ..
ellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
subfamily_LRR-DSP_pd Subfamily LRR-DSP 543-601 5.5e-12 39.3 In-house 201-259 (263) alignment 
Range on Protein: 543-601
Range on HMM: 201-259/263.0
VVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALH
.|    | |||.|||..|||  |.|.  . |  |...||  |||.||..||.  |. | 
lvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklf
subfamily_Slingshot_pd Subfamily Slingshot 538-601 7.7e-12 38.9 In-house 95-158 (169) alignment 
Range on Protein: 538-601
Range on HMM: 95-158/169.0
HDITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALH
..  ..|   .| |||.. |. | | . .|.... |. |..|| |..||.||..||.. |  |.
kgskvlvhckmGvsrsastviayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGile
subfamily_DSP8_pd Subfamily DSP8 540-602 1.1e-11 38.5 In-house 94-156 (159) alignment 
Range on Protein: 540-602
Range on HMM: 94-156/159.0
ITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALHQ
 . .| |  |.|||.|....|.| | ....|.  | |. .||. .||  |..||   |  |..
grvlvhvlaGisrsatvaiayimktlemsldeayrfvkekrptispnlnflgqLleyekelkl
0036282 (Phosphotyrosine protein) phosphatases II 523-597 1.2e-11 40.1 In-house 88-166 (174) alignment 
Range on Protein: 523-597
Range on HMM: 88-166/174.0
FLGGMRAVNQSMLSRHDITLVVTVAKGKSRSTTLVMCYLMATQKL-NVDDVLREVQRRR---PVAQPNRGFMQQLRTME
.|  ...|.. ... .. ...|    |..|. |||..||| ...| ...|.|. |...|   | . .. .....|. .|
llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfe
0046846 (Phosphotyrosine protein) phosphatases II 540-600 1.5e-11 39.9 In-house 110-172 (176) alignment 
Range on Protein: 540-600
Range on HMM: 110-172/176.0
ITLVVTVAKGKSRSTTLVMCYLMAT-QKLNVDDVLREVQRRRP-VAQPNRGFMQQLRTMEAAL
 . .|    |..|. |||..||. . . |.|...|..|...||  | ........|. .|  |
gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll
0049260 (Phosphotyrosine protein) phosphatases II 549-597 2.3e-11 39.1 In-house 99-146 (152) alignment 
Range on Protein: 549-597
Range on HMM: 99-146/152.0
GKSRSTTLVMCYLMAtQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
|..|. |||..|||  .......... |...||.| || |....|   |
GvgRtgtlvaaylml.lgvsleeavalvrekRpgavpnpgqlrflyefe
subfamily_DSP6_pd Subfamily DSP6 538-601 3.5e-11 36.9 In-house 92-155 (158) alignment 
Range on Protein: 538-601
Range on HMM: 92-155/158.0
HDITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALH
.. ...|    | ||| |....||| ...| ..|    |..|..   ||  ||.||   |  |.
kkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldferslr
subfamily_DSP10_pd Subfamily DSP10 541-602 3.5e-11 37.2 In-house 94-155 (159) alignment 
Range on Protein: 541-602
Range on HMM: 94-155/159.0
TLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALHQ
...|    | |||.|.|. |||. ..|.. |  . |. .||.  || .|| ||  .|  |..
rvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnk
0040439 (Phosphotyrosine protein) phosphatases II 538-597 3.8e-11 38.5 In-house 178-242 (249) alignment 
Range on Protein: 538-597
Range on HMM: 178-242/249.0
HDITLVVTVAKGKSRSTTLVMCYLM-----ATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
 .  ..|    |..|. |....|||      ................|| | .| .....|  ..
kggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeal
0045450 (Phosphotyrosine protein) phosphatases II 542-597 6e-11 38.1 In-house 237-300 (307) alignment 
Range on Protein: 542-597
Range on HMM: 237-300/307.0
LVVTVAKGKSRSTTLVMCYLMATQK--------LNVDDVLREVQRRRPVAQPNRGFMQQLRTME
 .|    |..|. |....||| .|         .............|| | .| .....|. ..
vlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeal
0039614 (Phosphotyrosine protein) phosphatases II 529-598 8.6e-11 37.3 In-house 211-286 (297) alignment 
Range on Protein: 529-598
Range on HMM: 211-286/297.0
AVNQSMLSR-HDITLVVTVAKGKSRSTTLVMCYLM-----ATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
.|.. . .   .   .|    |..|. |....|||      .....|.....|....|| | .. .....|. ...
lvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydall
0037934 (Phosphotyrosine protein) phosphatases II 537-598 9.1e-11 37.2 In-house 176-239 (243) alignment 
Range on Protein: 537-598
Range on HMM: 176-239/243.0
RHDITLVVTVAKGKSRSTTLVMCYLMATQ-KLNVDDVLREVQRRRPV-AQPNRGFMQQLRTMEA
 .. ...|    |..|. ||...||| .. ..............||  | ........|. ...
dsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeall
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 538-598 1.3e-10 34.9 In-house 90-150 (154) alignment 
Range on Protein: 538-598
Range on HMM: 90-150/154.0
HDITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
..  ..|.  || |||..|.. |||  .|...   |  ..  |.. .||.||..||  .| 
ennkvlvhsdkGvsrsaallisylmdklkislslalellkdsryiikPnqGflkqleifek
subfamily_STYXL1_pd Subfamily STYXL1 540-600 1.6e-10 34.4 In-house 93-153 (157) alignment 
Range on Protein: 540-600
Range on HMM: 93-153/157.0
ITLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAAL
 ...|   || |||......|||  .|..  . .  ... ..  .|||.|..||.  |  |
evvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCkenvkPnrafveqlseWekql
0040438 (Phosphotyrosine protein) phosphatases II 532-599 2.8e-10 35.4 In-house 203-274 (317) alignment 
Range on Protein: 532-599
Range on HMM: 203-274/317.0
QSMLsRHDITLVVTVAKGKSRSTTLVMCYLM-----ATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAA
...  ...  ..|    |..|. |....|||      .....|.....|....|| | .. .....| .... 
eale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalle
subfamily_MKPLT_pd Subfamily MKPLT 543-598 8.5e-10 32.4 In-house 103-158 (164) alignment 
Range on Protein: 543-598
Range on HMM: 103-158/164.0
VVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
.|   .|||||..  . .|.  ..  ...    .. || ...|||||..|| ..| 
lvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfee
subfamily_MKPLV_pd Subfamily MKPLV 543-598 8.5e-10 32.4 In-house 103-158 (164) alignment 
Range on Protein: 543-598
Range on HMM: 103-158/164.0
VVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
.|   .|||||..  . .|.  ..  ...    .. || ...|||||..|| ..| 
lvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfee
0051082 (Phosphotyrosine protein) phosphatases II 501-595 1e-09 33.7 In-house 53-148 (151) alignment 
Range on Protein: 501-595
Range on HMM: 53-148/151.0
WEANGAVPIPIGLVPSDAPG-PLFLGGMRAVNQSMLSRHDITLVVTVAKGKSRSTTLVMCYLMAtQKLNVDDVLREVQRRRP-VAQPNRGFMQQLRT
....|   . | ..  ..|| ||..  .... . .|.  .  ..|    ||.|. |||..|||. ........|.|....|| | ||| .|. ||. 
lpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfa
0038934 (Phosphotyrosine protein) phosphatases II 549-596 1.1e-09 33.7 In-house 125-172 (194) alignment 
Range on Protein: 549-596
Range on HMM: 125-172/194.0
GKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTM
|..|. ||| .||. ........ .. ....|| | ||......|.. 
GlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkr
subfamily_STYX_pd Subfamily STYX 542-598 2.8e-09 30.3 In-house 99-155 (166) alignment 
Range on Protein: 542-598
Range on HMM: 99-155/166.0
LVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
..|    | |||..||..|.| |  |.  .  . ||.||   .|| ||..||. .||
vlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyea
0043336 (Phosphotyrosine protein) phosphatases II 523-597 3e-09 32.2 In-house 195-273 (278) alignment 
Range on Protein: 523-597
Range on HMM: 195-273/278.0
FLGGMRAVNQSMLsRHDITLVVTVAKGKSRSTTLVMCYLM-----ATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
.|  ..||.. .    .  ..|    |..|. |....||.      ...........|....|| | ..  ....|. ..
lldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
0036941 (Phosphotyrosine protein) phosphatases II 544-599 3.2e-09 32.0 In-house 212-275 (297) alignment 
Range on Protein: 544-599
Range on HMM: 212-275/297.0
VTVAKGKSRSTTLVMCYLM--------ATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAA
|    |..|| |.....||         ...... ...... ..|| | .. .....|. ... 
VHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyealle
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 541-598 3.7e-09 30.3 In-house 88-145 (148) alignment 
Range on Protein: 541-598
Range on HMM: 88-145/148.0
TLVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEA
. .| .  | |||. |.. .|. ...  . . |  |. .|.  .|| ||..||  .| 
rvLvhlqmGvsrssalallwlidfkrvslkealalvkskrryvdpnlgfLkqLaeleq
0051429 (Phosphotyrosine protein) phosphatases II 547-598 8.7e-08 27.7 In-house 158-222 (272) alignment 
Range on Protein: 547-598
Range on HMM: 158-222/272.0
AKGKSRSTTLVMCYLMAtQKLN--------------VDDVLREVQRRRPVAQPNRGFMQQLRTMEA
. ||.|. |.|...|.. . ..              ......|....|| | .. .....|.  ..
saGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeall
subfamily_PTPMT1_pd Subfamily PTPMT1 543-597 8.9e-08 26.8 In-house 111-165 (171) alignment 
Range on Protein: 543-597
Range on HMM: 111-165/171.0
VVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTME
 |    |..||.||| |||| ..||. .. |. ....|.  . ..  ...|.  |
YvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeye
0047943 (Phosphotyrosine protein) phosphatases II 527-593 1.1e-06 23.7 In-house 192-264 (273) alignment 
Range on Protein: 527-593
Range on HMM: 192-264/273.0
MRAVNQSMLSR-HDITLVVTVAKGKSRSTTLVMCYLM-----ATQKLNVDDVLREVQRRRPVAQPNRGFMQQL
...|.. . .  .. . ||    |..|. |.....|.     ......|..... ....|| . ..  ....|
ielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 543-601 4.6e-06 19.8 In-house 84-142 (145) alignment 
Range on Protein: 543-601
Range on HMM: 84-142/145.0
VVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPVAQPNRGFMQQLRTMEAALH
 |    | ||| |. . .||   .. . .  |.|. .|  | ||  |...|  .|  |.
fvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrllaypnvtflknllnlekqlk
subfamily_DSP23_pd Subfamily DSP23 542-582 5.2e-06 21.2 In-house 87-127 (148) alignment 
Range on Protein: 542-582
Range on HMM: 87-127/148.0
LVVTVAKGKSRSTTLVMCYLMATQKLNVDDVLREVQRRRPV
. |  ..|. |. |.. |||.  .||   . . ||.|.|| 
vsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpg