Gene RNGTT-2 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily RNGTT
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP018_AA protein Get Run
MbreP018_AA_351-481 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_RNGTT_pd Subfamily RNGTT 354-481 7.6e-45 146.9 In-house 48-176 (189) alignment
Range on Protein: 354-481
Range on HMM: 48-176/189.0
FKTKFTNVGLVIDVSREPPPYLTNAPDV--PPYVKIATVSKRE-PEAESVAKLHKVLDNFWAnpDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGARE
.||. ...|||||.... ..| ... .     |||... .|.| ||||.|....|....|..  .|... ...||..||||.||...||||... .....
lktlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk..knpeevigvhCthGfnRtGFlivsyLvekedwsvea

ALHAFRKARPPGIKHEHFRAEFLRRYASVNS
|...|.|||||||..|....|.|||||.|..
avalFakaRppGiykedylkellrrYadvee

0038934 (Phosphotyrosine protein) phosphatases II 352-479 1.7e-23 78.7 In-house 48-176 (194) alignment
Range on Protein: 352-479
Range on HMM: 48-176/194.0
KAFKTKFTNVGLVIDVSREPPPYltNAPDVP----PYVKIATVSK-REPEAESVAKLHKVLDNFWANpdNARKDVIIHCHYGFNRSGFMACSYLVKRRGF
. .|..  ..|||||.. . . |  .. ...     |.|. ....   |  | . .  ...| | ..  .. . | .||..|..|.|.....||..|.|.
rylkllnvklglvidltnteryY..dpeefekagieylklpfpddgtvPsleillrfldlvdeflne..dpggvvaVHCkaGlgRtGtlvaaYLiyrlgm

GAREALHAFRKARPPGIKHEHFRAEFLRRYASV
 |.||.. || .||..| . ..  ..|.||  .
saeeAialfrekRpgaipnqdyleallkrykel

PTEN_1 400-481 1.8e-19 65.3 In-house 113-193 (196) alignment
Range on Protein: 400-481
Range on HMM: 113-193/196.0
VAKLHKVLDNFWANPDNaRKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPPGIKHEHFRAEFLRRYASVNS
. .  |.... . . .| .. |..||. | .|||.....||...... |.|||  .|..|||| ..  .. ..|. .|. ..
lfdicksfiewllsdpn.gnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaella

subfamily_DSP11_pd Subfamily DSP11 357-471 1e-18 61.9 In-house 53-169 (178) alignment
Range on Protein: 357-471
Range on HMM: 53-169/178.0
KFTNVGLVIDVSREPPPYLTNAP-DV-PPYVKIATVSKREPEAESVAKLHKVLDNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHA
| ...|||||..     | ...  |    |.|. .. .. |. | | |.......|  . ..  | . .||  | ||.|.. | ||... |. ...|..|
knkklGLvidltntdryykkkeltdegvkylklncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaiea

FRKARPPGIKHEHFRAE
| .||   . .|..  .
feearGhslerenylkd

Abhydrolase_6 Alpha/beta hydrolase family 99-276 1.5e-18 53.8 Pfam-A 66-227 (228) alignment
Range on Protein: 99-276
Range on HMM: 66-227/228.0
ARNVLIGHSYGTSLVVQLYQSLPTsfqsQVVGLVCCNAVTQ-----DascllqasmralslvptpV---LGLIRRWQARRGSESQSVARMVAADATNETK
.. ||.|||.|....... .. |      | ||| .... .     .                        |.||. |.|    . .|.   |.. ... 
gpvvlvGHSlGgavalaaaarrpd....lvrglvlidppgplpaspl..................rpagppllrrllagraaalrdlaarafarlfdgde

VMQLHWNtwTPTHVLQAMAA-GLQVVSLADYARVTIPVLLLAGAEDTVVPPEHTYSIYDTVPRVHgPHIAPNAKHNLIEEASELVNA
...|  .  . ....... |  |.    ...||...|||..||..| |||||.   . . .|..   .. |.| |.| .|| . |..
lealvra..daaalaellraalldadlrealarldvPvlviageaDrvvppeearrlaealpgar.vvvlpgagHllfleapdevae

0044763 (Phosphotyrosine protein) phosphatases II 360-471 1.9e-16 55.7 In-house 48-162 (178) alignment
Range on Protein: 360-471
Range on HMM: 48-162/178.0
NVGLVIDVSREPPPY----LTNAPDV--PPYVKIATVSKREPE-AESVAKLHKVLDNFWANPDnarKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREAL
......... | ...    .  .|.     |..| ..   .|.  | . .... .... ....   . |..||..|..||| ... ||.|..|. . ||.
githivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekg...gpvlVHCsaGvgRsgtlvaaylmkklglsleeai

HAFRKARPpGIKHEHFRAE
. .|..|| .. .....  
elvrerRp.ivpnpgqlrq

0049772 (Phosphotyrosine protein) phosphatases II 384-477 2.9e-16 55.5 In-house 183-270 (314) alignment
Range on Protein: 384-477
Range on HMM: 183-270/314.0
YVKIATVSKREPEAESVAKLHKVLDNFwanpdNARKDVIIHCHYGFNRSG-FMACSYLVKRRGFGAREALHAFRKARPPGIKHeHFRaEFLRRYA
|. | .    .|  | . .. ......     .. . |..||. | .|.| |... ||.|..|. ..|||. .|..|| .... .|. |.|..| 
ylripvpDgsaplledfdeflefieea.....dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRpinpnp.gfi.eqleqye

0048179 (Phosphotyrosine protein) phosphatases II 359-470 4.1e-16 54.5 In-house 28-135 (144) alignment
Range on Protein: 359-470
Range on HMM: 28-135/144.0
TNVGLVIDVSREPPPYLTNAPdVPPYVKIATVSKREPEA-ESVAKLHKVLDNFWANPdnarKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRK
 ....||... | .|.    . .  |... .     |.  | . .. . .... ...    . |..||..|..|.|.... ||.|..|. . |||. .|.
lgittvinlteeyepeflere.giqylhlpwpDhgvpdllellleflefieealeeg....gpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrs

ARPPGIKHEHFRA
.|| .. ..... 
rrpgavpnpgqlr

0048076 (Phosphotyrosine protein) phosphatases II 359-470 5.7e-16 54.0 In-house 28-133 (145) alignment
Range on Protein: 359-470
Range on HMM: 28-133/145.0
TNVGLVIDVSREPPPYLtnaPDVPPYVKIATVSKREPEA-ESVAKLHKVLDNFWANPdnarKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRK
 ....|.....|.. .    . .  |. . .    .|.  | . .. . .... ...    . |..||. | .|.|.... ||....|. . |||. .|.
lgittvlnltselelle...rlgiqylylpwpDhgvpdllellleflefieealkeg....gpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrs

ARPPGIKHEHFRA
.|| .. ..... 
qrpgavpnpgqlr

0036282 (Phosphotyrosine protein) phosphatases II 377-469 1.6e-15 52.7 In-house 65-159 (174) alignment
Range on Protein: 377-469
Range on HMM: 65-159/174.0
NAPDVPPYVKIATVSKREPEAESVAKLHKVLDNFWANpdNARKDVIIHCHYGFNRSGFMACSYLVKRRGF-GAREALHAFRKAR---PPGIKHEHFR
  . .  |... ..   .|. . . .. | .... ..  .  . |..||. |..|.|.... ||..|... ....||. .|..|   |... .....
lerlgiqylylpwpDhgvpdlsillefvkfveealse..dpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQy

0043147 (Phosphotyrosine protein) phosphatases II 360-470 5.7e-15 50.9 In-house 44-151 (172) alignment
Range on Protein: 360-470
Range on HMM: 44-151/172.0
NVGLVIDVSREPPPYLTNAPDVPPYVKIATVSKREPEAESVAKLHKVLDNFWANPDNarKDVIIHCHYGFNRSGFMACSYLVKrRGFGAREALHAFRKAR
........ ..  ..    . .  |  .       | .| . .. . .|.. |. ..  . |..||..|..|.|.... ||.. .|. . ||.. .|..|
githivnltellydpellerlgiqylylpwpDhgvpllellleflefidellalspg..gpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekR

PPGIKHEHFRA
| .. ..... 
pgavqnpsqyr

0041856 (Phosphotyrosine protein) phosphatases II 360-466 9.9e-15 50.0 In-house 58-157 (182) alignment
Range on Protein: 360-466
Range on HMM: 58-157/182.0
NVGLVIDVSrePPPYLTNAP--DVPPYVKIATVSKREPEAESVAKLHKVLDNfwanpdnARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRK
.........  ...|  .     .  |...       |. ... .. .   .         . |..||..| .|.|.... ||.|..|....||.. .|.
gittivnlt..eelywpellerlgiqylylpwpDhgvpdldelldfieevle.......eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrs

ARPPGIKHE
.|| .. ..
rRpgmvitp

0049260 (Phosphotyrosine protein) phosphatases II 362-470 1e-14 49.9 In-house 35-140 (152) alignment
Range on Protein: 362-470
Range on HMM: 35-140/152.0
GLVIDVSREPPPYLTNAPDVPPYVKIATVSKREPEAESVAKLHKVLDNFWanPDNARKDVIIHCHYGFNRSGFMACSYLVKrRGFGAREALHAFRKARPP
. .. . .. . .    .  . |  . .     |. . . .    .....    .  . |..||..|..|.|.... ||.. .|. . ||.  .|..|| 
ttivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekRpg

GIKHEHFRA
.. ..... 
avpnpgqlr

DSPc Dual specificity phosphatase, catalytic domain 357-471 2.6e-14 48.2 Pfam-A 15-126 (133) alignment
Range on Protein: 357-471
Range on HMM: 15-126/133.0
KFTNVGLVIDVSREPPPYLTNAPDVPPYVKIAtVSKrEPEAESVAKLHKVLdNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFR
.  .. |||.|..| |   . ..    |..|  |   | |.. ...| ..  .| .. .. .| |..||  | .||. ... || |.... ..||.....
eklgitlvinvtkevpnnnaikkseieylrip.ved.etetkiskeleeav.efiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvk

KARpPGIKHE-HFRAE
. | . | .  .| ..
err.skispnagflrq

DSPc Dual specificity phosphatase, catalytic domain 357-471 2.6e-14 48.2 In-house 15-126 (133) alignment
Range on Protein: 357-471
Range on HMM: 15-126/133.0
KFTNVGLVIDVSREPPPYLTNAPDVPPYVKIAtVSKrEPEAESVAKLHKVLdNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFR
.  .. |||.|..| |   . ..    |..|  |   | |.. ...| ..  .| .. .. .| |..||  | .||. ... || |.... ..||.....
eklgitlvinvtkevpnnnaikkseieylrip.ved.etetkiskeleeav.efiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvk

KARpPGIKHE-HFRAE
. | . | .  .| ..
err.skispnagflrq

0037934 (Phosphotyrosine protein) phosphatases II 379-468 1.3e-13 46.6 In-house 133-230 (243) alignment
Range on Protein: 379-468
Range on HMM: 133-230/243.0
PDVPPYVKIATVSKREPE-AESVAKLHKVLDNFWAN-----PDNARKDVIIHCHYGFNRSGFMACSYLVKRR-GFGAREALHAFRKARPP-GIKHEHF
  |  |  ..      |.  |.. .... . .|  .      ..  . |..||. | .|.| ... ||.... |... ||.. .|. ||  ..  ...
rlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsq

Abhydrolase_5 Alpha/beta hydrolase family 98-265 2.1e-13 36.7 Pfam-A 60-145 (145) alignment
Range on Protein: 98-265
Range on HMM: 60-145/145.0
TARNVLIGHSYGTSLVVQLYQslptsfqsqvvglvccnavtqdascllqasmralslvptpvlglirrwqarrgsESQSVARMVAADAtnetkvmqlHwn
. | .|.|||.|......| .                                                      . ..|. .|. ..         .  
lervilvGhSlGGgvalelag......................................................rddrvkglvllap.........f..

twtpthvlqamaaglqvVSLADYARVTIPVLLLAGAEDTVVPPEHTYSIYDTVPRVHGPHIAPNAKHN
                  . .| |..|.||||. |..|.|||||.   ... .|  .  .. ..| |.
.................pdgedlakltlpvllihGtrDgvvppeeaeklakalpgdaelvviegasHf

0046846 (Phosphotyrosine protein) phosphatases II 392-468 4.5e-13 44.8 In-house 87-161 (176) alignment
Range on Protein: 392-468
Range on HMM: 87-161/176.0
KREPEAESVAKLHKVLDNFWANPdnarKDVIIHCHYGFNRSGFMACSYLVKR-RGFGAREALHAFRKARP-PGIKHEHF
   |. | . .| . ....  .     . |..||. | .|.| ... ||... .|. . |||. .|. ||   . ....
hgvpdlelllellefirealkeg....gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQ

PTPc_motif_SM00404 359-470 6.4e-13 43.8 In-house 26-132 (140) alignment
Range on Protein: 359-470
Range on HMM: 26-132/140.0
TNVGLVIDVSREPP-PyltnapDVPPYVKIATVSKREPEAESVAKLHKVLDNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRK
 .. .||.|..| . .      .  . ..|  .  .. | . ..|  . . .|  |  . .. |..||  | .||. ... || ..|.. ..||......
lgithvinvteevslt......kensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvke

ARpPGIKHE-HFRA
 | | |..  .| .
rR.piispnlnfvr

0042113 (Phosphotyrosine protein) phosphatases II 360-468 6.6e-13 44.1 In-house 76-231 (245) alignment
Range on Protein: 360-468
Range on HMM: 76-231/245.0
NVGLVIDVSREPPP-------------------------------------------YLTNAPDVPPYVKIATVSKREPE-AESVAKLHKVLDNFWANpd
..  ......| .                                            .      |  |  .      .|.  |.. .... .... |.  
gittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae..

NARKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGIKHEHF
.. . |..||. | .|.| ... ||.     |..|. . ||.. .|. ||  .  ...
dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsq

0040439 (Phosphotyrosine protein) phosphatases II 396-468 3.3e-12 42.0 In-house 158-234 (249) alignment
Range on Protein: 396-468
Range on HMM: 158-234/249.0
EAESVAKLHKVLDNFWANPdNARKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGIKHEHF
  |.. .. . .... ..  .  . |..||. | .|.|.... ||.     |..|. . ||.. .|..|| ..  ...
sfedlldfieavrkaleel.pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeq

Abhydrolase_1 alpha/beta hydrolase fold 102-279 5.5e-12 33.0 Pfam-A 47-229 (230) alignment
Range on Protein: 102-279
Range on HMM: 47-229/230.0
VLIGHSYGTSLVVQLYQSLPTsfqsQVVGLVCCNAV----TQDASCLLQAsMRALSLVPTPVLG-LIRRWQARRGSES---QSVARMVAADATNETKVMQ
.|.|||.|. .. ....  |.     | ..|....|    .   | .|.. .  | |.  .| | | .. .. .|  |   ||. |    |  .. .  .
tlvGhSmGGmialayaaeypd....rvkamvllgtvavlsdglssdvlnr.gstltlladnvagrlskgikplqgdasvqaqsllrpqvtdflkrfdans

LHW---NTWTPTHVLQAMAAGLQVVSLADYARVTIPVLLLAGAEDTVVPPEHTYSIYDTVPRvHGPHIAPNAKHNLIEEASELVNALLT
. .   ....... |.|..  |.    ..  ....|.|.. | .| .||... ... ...|. .  .  ... | . ... ...|.|..
yaregetraldgkllaalgrdlvwdvtetlktilvptlvisgtdDplvpykaseklaelipk.sqlvvidgpgHlafldkpdeinkliv

0045450 (Phosphotyrosine protein) phosphatases II 399-468 1.1e-11 40.5 In-house 216-292 (307) alignment
Range on Protein: 399-468
Range on HMM: 216-292/307.0
SVAKLHKVLDNFWANPdNARKDVIIHCHYGFNRSGFMACSYLVKRRG--------FGAREALHAFRKARPPGIKHEHF
.. .. . .... ..  .  . |..||. | .|.| ... ||..|..        . ..||.. .|. || ..  ...
elldfieevrkaleel.pkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeq

0048567 (Phosphotyrosine protein) phosphatases II 400-463 1.1e-11 39.3 In-house 56-122 (157) alignment
Range on Protein: 400-463
Range on HMM: 56-122/157.0
VAKLHKVLDNFWANPDNARKDVIIHCHYGF---NRSGFMACSYLVKRRGFGAREALHAFRKARPPGI
. .. ..|..|.  ...|.| ...||..|     |.......||... || ..||.. .| .||. .
lyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsv

0040438 (Phosphotyrosine protein) phosphatases II 398-465 1.2e-11 39.9 In-house 192-261 (317) alignment
Range on Protein: 398-465
Range on HMM: 192-261/317.0
ESVAKLHKVLDNFWAnpdNARKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGIKH
... .. . .... .   .  . |..||. | .|.|.... ||.     |..|. . ||.. .|..|| ..  
dllldfleavreale...dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqt

0039614 (Phosphotyrosine protein) phosphatases II 399-468 1.4e-11 39.9 In-house 204-277 (297) alignment
Range on Protein: 399-468
Range on HMM: 204-277/297.0
SVAKLHKVLDNFWANPdNARKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGIKHEHF
.. .. . .... |.  .  . |..||. | .|.| ... ||.     |..|. . ||.. .|..|| ..  ...
llleflelvrealael.pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsq

0051082 (Phosphotyrosine protein) phosphatases II 360-463 3.2e-11 38.5 In-house 33-136 (151) alignment
Range on Protein: 360-463
Range on HMM: 33-136/151.0
NVGLVIDVSREPPPYlTNAPDVPP----YVKIATVSKREPEA----ESVAKLHKVLDNfwanpdNARKDVIIHCHYGFNRSGFMACSYLVKrRGFGAREA
..  ....  |.... ...  .|     .. |  ..  .|      ..|......|..      .  . |..||. | .|.|.... ||.. .|. . ||
giktivnlrseeerg.ycpeylpelgievlhipildwpdpglplsfdavleflellld......kkngpvlvHCsaGkgRTGtlvalylml.lgvsleea

LHAFRKARPPGI
|. .|. ||  .
leeyrlkrpgvv

subfamily_DSP23_pd Subfamily DSP23 363-464 5.3e-11 37.4 In-house 34-130 (148) alignment
Range on Protein: 363-464
Range on HMM: 34-130/148.0
LVIDVSREPPPYLTNAPDVPpYVKIATVSKREPEAESVAKLHKVLDNfwAnpDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPPG
 .. .. | .|    .|..  .|..       |  | | .. .|...  |  ..  . | .||  |. |.| |   |||| |.. | ||.   |. ||  
ylvslteegrphveatpnlt.lvrlriddyhppaleqvvefvrvvee..a..eekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgs

IK
..
ve

0045098 (Phosphotyrosine protein) phosphatases II 412-468 9.8e-11 37.0 In-house 194-260 (278) alignment
Range on Protein: 412-468
Range on HMM: 194-260/278.0
AN------PDNARKDVIIHCHYGFNRSGFMACSYLVKRR---GFGAREALHAFRKARPP-GIKHEHF
         ..  . |..||..| .|.| ... ||....   |. . ||.. .|. ||   . ....
slllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleq

0051429 (Phosphotyrosine protein) phosphatases II 360-479 1.1e-10 37.2 In-house 45-231 (272) alignment
Range on Protein: 360-479
Range on HMM: 45-231/272.0
NVGLVIDVSREPPPYLTNAPDVPP---YVKIATVSKREPEA----------------------------------------------------ESVAKLH
..  ..|. .|      . . ..|   |. . ...  .|.                                                     |.. .| 
giktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallell

KVLDNfwanpdnaRKDVIIHCHYGFNRSGFMACSYLVKrRGFG--------------AREALHAFRKARPPGIKHEH-------FRAEFLRRYASV
..| .         . |..||. | .|.|.... .|.  .|..              ..||..  |..||  . .|.       . .|.||...||
ellld........ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsv

0043336 (Phosphotyrosine protein) phosphatases II 402-464 1.1e-09 33.6 In-house 197-261 (278) alignment
Range on Protein: 402-464
Range on HMM: 197-261/278.0
KLHKVLDNFWAnpdNARKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGIK
.. |..... .   .  . |..||. | .|.| ... ||.     |..|. . ||.. .|. ||  . 
dflkavreale...dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavq

0047943 (Phosphotyrosine protein) phosphatases II 409-465 2.4e-09 32.5 In-house 197-257 (273) alignment
Range on Protein: 409-465
Range on HMM: 197-257/273.0
NFWAN-PDNarKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGIKH
.. .. |.|  . |..||. | .|.| ... .|.     |..|. . ||.. .|. || ..  
kalealpsn..gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqt

0036941 (Phosphotyrosine protein) phosphatases II 400-465 6.6e-09 30.9 In-house 190-262 (297) alignment
Range on Protein: 400-465
Range on HMM: 190-262/297.0
VAKLHKVLDNFWANPdNARKDVIIHCHYGFNRSGFMACSYLV--------KRRGFGAREALHAFRKARPPGIKH
. .. . .... ..  .  . |..||. | .||| ... .|.        |..|.   ||.. .|. ||  .  
lldfielvrkvlkll.psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqt

0046845 (Phosphotyrosine protein) phosphatases II 397-464 1.2e-08 30.2 In-house 184-258 (284) alignment
Range on Protein: 397-464
Range on HMM: 184-258/284.0
AESVAKLHKVLDNFWANpDNARKDVIIHCHYGFNRSGFMACSYLVKRR--------GFGAREALHAFRKARPPGIK
.|.. .. . ....  |  .  . ...||. | .|.| ... .|....        |. . ||.. .|. ||  . 
pedlleflrlvrellen.lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvq

0050432 (Phosphotyrosine protein) phosphatases II 399-463 3e-08 28.8 In-house 218-282 (308) alignment
Range on Protein: 399-463
Range on HMM: 218-282/308.0
SVAKLHKVLDNFWanPDnarKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGI
.. .. . ....   |.   . ...||. | .|.| ... .|.     | .|. . ||.. .|. ||  .
illdflelvrksl..pg...gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmv

subfamily_PTPDC1_pd Subfamily PTPDC1 419-465 3.9e-08 28.0 In-house 115-161 (182) alignment
Range on Protein: 419-465
Range on HMM: 115-161/182.0
KDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPPGIKH
. | .||| |  | | . ..|||  . . | .|..  |. ||  |. 
gkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqt

0051299 (Phosphotyrosine protein) phosphatases II 406-463 8.7e-08 27.4 In-house 210-269 (288) alignment
Range on Protein: 406-463
Range on HMM: 210-269/288.0
VLDNFWAnpdNARKDVIIHCHYGFNRSGFMACSYLV-----KRRGFGAREALHAFRKARPPGI
 .... |   .  . |..||. | .|.| ... .|.     |..|. . ||.. .|. ||  .
lvrkala...sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmv

subfamily_PTPMT1_pd Subfamily PTPMT1 399-479 1.1e-07 26.5 In-house 89-167 (171) alignment
Range on Protein: 399-479
Range on HMM: 89-167/171.0
SVAKLHKVLdNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPpGIKHEHFRAEFLRRYASV
...||.| . .|  .  .  | | .||. |  ||. .. .||.|.. .   |||.| .| |.  |. .... . |..| . 
dleklekgv.efiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRk.iirlakkqwkalqeyeek

subfamily_DSP19_pd Subfamily DSP19 395-461 2e-07 25.5 In-house 67-132 (152) alignment
Range on Protein: 395-461
Range on HMM: 67-132/152.0
PEAESVAKLHKVLDnFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPP
||.. .. |...|| |  .  ..   |..||. |  ||  .. .||.|..    .|||.  |.|||.
petdllsylkeald.FieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpc

subfamily_CDC14_pd Subfamily CDC14 405-462 5.2e-07 23.8 In-house 250-307 (328) alignment
Range on Protein: 405-462
Range on HMM: 250-307/328.0
KVLDNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPPG
... .| .  ..|.  ...||. |. | | .  .||.|. .| | ||.  .| .||  
aivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGs

subfamily_PTEN_pd Subfamily PTEN 400-459 6.1e-07 24.6 In-house 98-156 (184) alignment
Range on Protein: 400-459
Range on HMM: 98-156/184.0
VAKLHKVLDNfWANPDNaRKDVIIHCHYGFNRSGFMACSYLVKRRGFGAR-EALHAFRKAR
.... . ... | . |. .. |..||. |  |.| . ..||.|.. .    |||. | .||
leeivediek.wleedk.knvvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaR

Peptidase_S9 Prolyl oligopeptidase family 177-253 8.6e-07 14.7 Pfam-A 98-173 (213) alignment
Range on Protein: 177-253
Range on HMM: 98-173/213.0
VARMVAADATNETkVMQLHWNTWTPTHVLQAMAAGLQVVSLADYARVTIPVLLLAGAEDTVVPPEHTYSIYDTVPRV
|. ... . ...   .. ... ..     ...   |. .| ||  ... |.||. | ||. |||.... ....  . 
vvdwltymsdtsl.lteaeymeygnpeeneegyeelspyspadnvkaypplllihGeeDdrvppaealklvaaLqka

subfamily_DSP12_pd Subfamily DSP12 410-468 9.8e-07 23.3 In-house 74-132 (155) alignment
Range on Protein: 410-468
Range on HMM: 74-132/155.0
FWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARPPGIKHEHF
|  .  . .. |..||..|  ||  .   ||.|. ..   .||.. ....|     | |
FieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeiepNegF

subfamily_DSP3_pd Subfamily DSP3 419-459 1e-06 22.5 In-house 98-138 (162) alignment
Range on Protein: 419-459
Range on HMM: 98-138/162.0
KDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKAR
  |..||. |. ||  ..  ||. || . . ||... || |
gkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkkR

subfamily_DSP14_pd Subfamily DSP14 360-460 2.5e-06 21.5 In-house 31-125 (157) alignment
Range on Protein: 360-460
Range on HMM: 31-125/157.0
NVGLVIDVSREPPPylTNAPDVPpYVKIATvsKREPEAESVAKLHKVLDNFwANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKAR
.. |.|.|..| |   |...|.  .||..   . .|||. .. . .| |.   . ...   ...||  |  ||  ..  ||.| .    ||| .. ..||
kitliinvtvelpn..tklkdie.rvkvpv..eDnpeaklakhfdevadki.eevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaR

P
|
p

AXE1 Acetyl xylan esterase (AXE1) 213-269 4.5e-06 11.6 Pfam-A 253-307 (320) alignment
Range on Protein: 213-269
Range on HMM: 253-307/320.0
QVVSLADyaRVTIPVLLLAGAEDTVVPPEHTYSIYDTVPRVHGPHIAPNAKHNLIEE
 |. ||.  |.  |||| .| ||.| ||   ...|  .      .. .. .|. ...
DvknlAk..rikapvllavgLeDkvcpPstvfaaynkleteKelkvyeeyahealka

PhoPQ-activated pathogenicity-related protein 220-278 6.7e-06 11.1 Pfam-A 257-314 (367) alignment
subfamily_DSP10_pd Subfamily DSP10 398-460 7.6e-06 19.9 In-house 72-134 (159) alignment
Range on Protein: 398-460
Range on HMM: 72-134/159.0
ESVAKLHKVLDNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARP
. . .  ..  .|  .  .  . |..||. |  ||  .. .||.|...   ..| .  ...||
qnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrp

FSH1 Serine hydrolase (FSH1) 220-263 8.5e-06 11.7 Pfam-A 157-206 (212) alignment
Range on Protein: 220-263
Range on HMM: 157-206/212.0
YARVTIPVLLLAGAEDTVVPPEHTYSIYDTVPR------VHGPHIAPNAK
  ....|.|   | .||||..| . ...... .       .| |  || |
edkiqtpsLhvlGelDtvvdeerseaLaeafknsskvlkHpggHfvPnkk

subfamily_DSP1_pd Subfamily DSP1 397-460 9.3e-06 19.8 In-house 74-137 (163) alignment
Range on Protein: 397-460
Range on HMM: 74-137/163.0
AESVAKLHKVLDNFWANPDNARKDVIIHCHYGFNRSGFMACSYLVKRRGFGAREALHAFRKARP
 . . .. .   .|  .  ...  |.|||. |  ||  .   ||.|.. .   || .  .. |.
kadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRs