Gene MTMR6 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR6
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP023_AA protein Get Run
MbreP023_AA_118-502 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR6_pd Subfamily MTMR6 107-499 2.5e-197 647.9 In-house 6-396 (397) alignment 
Range on Protein: 107-499
Range on HMM: 6-396/397.0
FRPQRKIDSDVDGWALYSPMAEYGRMGVPNPQWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQ
..|... ...|.||.|.. .|||.|||||| .|...|.|..|.|| ||.|.||.|.|.|.|. ..|.|||||.||||||||...|.||||||.|||.|..
ykpkkdkeekvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqplsgfs

AkRSEDDEALLEFIRLCNPHSELpLIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCH-DHQIGIQECAWLK
| |...||.|||.|| .||.||| |..|||||..||.||||||||.||.. |.|....|.||||||.|| ||..|.......|... ... |.....|||
a.rcledeklleairkanpnsel.lyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsglessgwlk

HIQAVLKTTMVITRYI-QDGHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGFLKGSGREVSPIFLQLLECTWCLQR
||.|||.....|.... ..|.|||||||||||||||.|||| |.||||||||.|..|||||||||||||| .|.|.|.....||||||.|.|||.|.|..
hikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvwqlle

QFPLAFEFNESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDASQDPegGVLNPSLAPQHFELWSAMYCRWE
||| ||||||.||...||...||.|||||||||..|||.||.|||.|.|.||..||....||.|.|...   .||.|..||....||.|.|.|..
qfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetek..evlkpdtapaalklwralynrfd
subfamily_MTMR1_pd Subfamily MTMR1 117-500 4.7e-135 442.8 In-house 4-388 (389) alignment 
Range on Protein: 117-500
Range on HMM: 4-388/389.0
VDGWALYSPMAEYGRMGVPNP-QWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQAKRSEDDEA
 |||..|.|.||. |.|..|  .|.... |..|.||.|| ..|..|..|. |.   .|.||||.||||||.| ..|||.| |..|||.|...|||..||.
edGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedek

LLEFIRLCNPHSElPLIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQIGIQECAWLKHIQAVLKTTM
.|..|. .| .||  |.|.| |...||.|||| ||| |. | |.|..| |  |.|||..| ||. | ..   |   ....  ...  ||.||...|....
ylqaileanaqse.kllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWlehiklilagav

VITRYIQDG-HSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGF--LKGSGREVSPIFLQLLECTWCLQRQFPLAFEF
 | . ..   .|||||||||||||||  ||| |.||.|||||||..|||||||||||||| .| |    . | .| ||.||| ..| | |.|||| ||||
kivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFef

NESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDASQDpeGGVLNPSLAPQHFELWSAMYCRWES
||.||| . | |.|| ||||| |.|..|...|..|.| | |||. |.|.||.||.|. ...    ||.| .. .. |||.  |.||..
neefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeele..kkvlypkaslrrlelWkeyylrwnp
0040695 (Phosphotyrosine protein) phosphatases II 117-499 5.7e-134 440.5 In-house 5-386 (388) alignment 
Range on Protein: 117-499
Range on HMM: 5-386/388.0
VDGWALYSPMAEYGRMGVPNPQWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQAKRSEDDEAL
..|| ||... |. |.|...  |. ...|. | |||.| . |..|.|.. |.   .|.||||.|.|||||  ..|.|...|..|||.|.. .|| .|| |
eegwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledekl

LEFIRLCNPHSElPLIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQIGIQECAWLKHIQAVLKTTMV
|| |. ..| ..  |.|||.||..||.||.|.|.|.||.. |.|..| | .|.|||..| ||. |..|   . . ... . ..|. ||..|. .|.....
leailkllpnls.kllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldaclnvpdslnllslleesgwldliklilelavl

ITRYIQDGHS-VLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGFLKG--SGREVSPIFLQLLECTWCLQRQFPLAFEFN
|......|.| ||||||||||||.| .||| |.|||||||.||..||||||||||||||.|| |.| .  .  |.||.||. |.|.|.|.||||.|||||
ivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFn

ESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDASQDPeggVLNPSLAPQHFELWSAMYCRWE
| .|. ..| |.|| |||||.|.|. |......|||.| ||||.||||||.||.|| |..    || ||| .... ||. .|.|| 
erlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpssle...vllpslsvldlllWleyylrwl
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 111-499 3.6e-130 426.8 In-house 7-403 (404) alignment 
Range on Protein: 111-499
Range on HMM: 7-403/404.0
RKIDSDVDGWALYSPMAEYGRMGVPNP-QWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQAKR
.|   . ||| .|... || |.|...  .|.  ..|. |.||.|| ..| .|.|.. |.   .|.||||.|.||||.  . ... | |..||| |.. .|
ekksvledgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksr

SEDDEALLEFIRLCNPHSElPLIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQ-IGIQECAWLKHIQ
||.|| |.. ||. ....| .|.|.|.||..||.||.| |.|.|... |.|| .|| .|||||..| ||. | || . .   ...    ...  || ||.
seedEklinsirkaktqle.tlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlselessrWldhik

AVLKTTMVITRYIQ-DGHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGF-LKGSGREVSPIFLQLLECTWCLQRQF
 .|.... | . |. ...|||||||||||||.| .||. |.||||||||||.||||||||||||||| .|.|   . |  | |||||| ..| . | .||
lllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyqltkqf

PLAFEFNESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDASQDPEGGVLNPSL-----APQHFELWSAMYCRWE
|  |||||.||| . | | ||.||||| ..|. | ...|.. |.| |..| . |||..||.| ...  .    . |       .....||| .|.||.
ptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWseyylrwr
Myotub-related Myotubularin-like phosphatase domain 112-442 3.5e-119 390.7 Pfam-A 13-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 112-442 3.5e-119 390.7 In-house 13-352 (353) alignment
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 114-499 6.2e-100 326.8 In-house 10-405 (405) alignment 
Range on Protein: 114-499
Range on HMM: 10-405/405.0
DSDVDGWALYSPMAEYGRMGVP-------NPQWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQ
.| .||| .|    || |. .        |  |.  . |. |..| .|  .| . |  .  .      |||| |.| ||.     .|.| ||.||| |..
tssidgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgie

AKRSEDDEALLEFIRLCNPHSELplIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQI--------GI
  |  .||     . |  |   |   ..|.||..||.|| | | ||||.  | ||.| |  | ||| .| ||. || | |  .  .||           |
rarcpedelycsslalsapsktl..ylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyi

QECAWLKHIQAVLKTTMVITRYIQDGHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGFLKGSGREVSPIFLQLLEC
.|  |. ||...|... . .  |  | |.||||||||||| |  ||. ..|||||||| |. ||||||||||||||  | | | |   | |||| |.|.|
eetgwishiksileaatfsaelilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldc

TWCLQRQFPLAFEFNESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDAsQDPEggVLNPSLAPQHFELWSAMYCRW
 . |  |||| |||  |.|. . | .||||.|||| |||. | . ... .| | || .      |.||.|.  || .   ..| |  . .||| | | | 
cfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynp.qdiq..sikpklysrclelwkacymrv

E
|
e
subfamily_MTMR9_pd Subfamily MTMR9 115-498 5.3e-96 314.1 In-house 10-392 (393) alignment 
Range on Protein: 115-498
Range on HMM: 10-392/393.0
SDVDGWALYSPMAEYGRMGVPNPQWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQAKRSEDDE
   ||.  .... |.... .. ..|   . |. ...|..|. .. .| ... |.. |||.||.. |.|||||| ....|.. |..|||.| . || ..||
iledgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckede

ALLEFIRLCNphseLPLIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKR-NSPCHDHQIGIQECAWLKHIQAVLKT
.||. .   .       .|||||    |..... | |.|  . |.. . . . .|.....  ||  |..| .  .   . .   .... ||......|..
kllnlvlkkl....kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadllea

TMVITRYIQD-GHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGFLKGS---GREVSPIFLQLLECTWCLQRQFPLA
..|..  ... | .|.|| ..| | | |  ||| |.|||..||..|.  |||.||.  || |  |.  .  .    .. .|.||  |.| . . .|||..
alvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpas

FEFNESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSR--KSEFINPFYDAsqdpEGGVLNPSLAPQHFELWSAMYCRW
|||||..||...   .|..|||||...|. |...||...|.| |||. .    ..|.||.|.|    .  |. || ||| .|||| .|.||
FEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea....naeviwpsvapqslelWselylrw
subfamily_MTMR3_pd Subfamily MTMR3 231-496 3.7e-87 285.9 In-house 175-440 (442) alignment 
Range on Protein: 231-496
Range on HMM: 175-440/442.0
LIIVDTRPRMNAMANKAAGKGFENMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQIGIQECAWLKHIQAVLKTTMVITRYIQD-GHSVLV
|.||| |    |.||.| | |.|. | |.|| ..| |. |||..| |.|.| .  ..     ..   ...  ||...  .||... ..  ..  |..|||
llivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpvlv

HCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGFLKGSGR--EVSPIFLQLLECTWCLQRQFPLAFEFNESFLIAMHDCLHSC
|||||||||.|  .|| |.|||||||.||. ||.|.|||.||||| || |. . ..   | .|.||| |..   |||||| .|||||.||. .    .||
hCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysc

KFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDASqdpEGGVLNPSLAPQHFELWSAMYC
 |||||.|.|..|.. |..||| | ||.| ... |. |  |. .   .  || |.   ....|||..| 
lfGtflansekereeekvkertlsvWsllrakekeyrnllykek...teavllpavsvrelklwsevyl
subfamily_MTMR5_pd Subfamily MTMR5 239-491 8.2e-50 162.0 In-house 207-475 (483) alignment 
Range on Protein: 239-491
Range on HMM: 207-475/483.0
RMNAMANKAAGKGFeNMEGYTNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQIG-----IQECAWLKHIQAVLKTTMVITRYIQ-DGHSVLVHCS
.. .. .|.  |.. ..| .... .    . .|  .. |.. |..|   . . ....       ...  ||. |...|. . ...  .. .| ||||   
aLYvlgeksqlknv.ksevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslE

DGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNG-FLKGSGREVSPIFLQLLECTWCLQRQFPLAFEFNESFLIAMHDCLHSCKFGT
|||| |||  ||| |.|||||||.||. ||.|||||.|||.| .|    |  ..  ..|.||| |.| . ..||||||||||. .|  .     |..| |
dGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrt

FLGNCEQARRDAKL--H--------ERTQSAWSYLYSrKSEFINPFYDASQDP-EGGVLNPSLAPQHFELW
|| ..|. | .. |  .        . ..| | |.   ...    ||.   .| |  || ||    ....|
fllDseyerlesgllyeekaekrakkagksvwdyidr.qhkrspifynflyspdesevlrPssnvsslkvW
subfamily_MTMR10_pd Subfamily MTMR10 300-498 5.3e-40 129.3 In-house 161-377 (380) alignment 
Range on Protein: 300-498
Range on HMM: 161-377/380.0
ECAWLKHIQAVLKTTMVITRYI-QDGHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTIEGYIVLIEKEWLSFGHKFLDRNGFLKGSGREVSPIFLQLLEC
.  ||. ....|.|.. ... . ....||..  |.| |     .||| |||||.||||.|.  ||.||| . ||.|||| | .| |  . ||.||  |.|
ktrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespvfllFldc

TWCLQRQFPLAFEFNESFLIAMHDCLHSCKFGTFLGNCEQARRDA----KLHERTQSAWSYLYSRKSE--FINPFYD-----------ASQDPEGGVLNP
.. | .||| .|||.|.||||..|. ||. |.||| |.|..|  |    ..  ...| . .  . |.|  . .. |            |..  .  .. |
vdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvsssplliakselkendllkdeldyrqglyaeiiksirrlaaaksylrseiirP

SLAPQHFELWSAMYCRW
 |     .||.  | ||
llqipdiqlWdeCYlRW
subfamily_pats1_pd Subfamily pats1 386-472 2e-23 74.7 In-house 550-636 (691) alignment 
Range on Protein: 386-472
Range on HMM: 550-636/691.0
REVSPIFLQLLECTWCLQRQFPLAFEFNESFLIAMHDCLHSCKFGTFLGNCEQARRDAKLHERTQSAWSYLYSRKSEFINPFYDASQ
|  ||||.|.|.  | ||..||. ||||||.|. . .  .| .||.|| .  . . . |. .|..| ||.    || ||| .|  | 
rsfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhsa
subfamily_pats1_pd Subfamily pats1 259-378 6.9e-21 66.3 In-house 334-457 (691) alignment 
Range on Protein: 259-378
Range on HMM: 334-457/691.0
TNCRLEFHGIENIHTMRGSLNALVKASKRNSPCHDHQIGIQECAWLKHIQAVLKTTMVITRYIQDGHSVLVH-CSDGWDRTAQT---CSLAGLMLDPYYR
  ....|  .   . ..   . |...        |    |.|  |.  .. .|.... .. .. .|.|||..  .|. . . .     ||| ...||.||
issniiflslPtrekveerffdllqsilsldgsddewkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyr

TIEGYIVLIEKEWLSFGHKFLDRN
|..|. |||||||||.|. | ..|
tldGfkvliekewlsyGfPfskin
subfamily_MTMR3_pd Subfamily MTMR3 126-220 1.7e-20 66.2 In-house 30-125 (442) alignment 
Range on Protein: 126-220
Range on HMM: 30-125/442.0
MAEYGRMGV-PNPQWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQPLTGVQAKRSEDDEALLEFI
 .|. |.|   . .|.  | |. ..||..| ..| .|.|.| ..   .|.||| .|||.. .  ..|.|.. ||.||  |. . |...|| ||. |
keeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkai
PTPc_DSPc_SM00012 304-424 1.6e-10 36.5 In-house 23-104 (105) alignment 
Range on Protein: 304-424
Range on HMM: 23-104/105.0
LKHIQAVLKTTMVITRyiqdGHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRTiegyivliekewlsfghkfldrngflkgsgrevspIFLQLLECTWCLQ
|....|| | .  ...    ...|.||||.|..||.. . |. |. . ...|                                    ....... . | 
lellravkknknkses....skpvvVhCsaGvgRtgtfvaldillqqleket...................................kevdifqivkelr

RQFPLAFEFNESFLIAMHDCL
.| | .....| .|. .. .|
kqRpgmvqteeqylflyrall
DUF1943 Domain of unknown function (DUF1943) 536-630 6.6e-08 18.0 Pfam-A 205-299 (302) alignment 
Range on Protein: 536-630
Range on HMM: 205-299/302.0
AAASTETNPSTEDPIPSpLEVVEVEVEVEVEVEVEVEVEVEVEVEvEVEVEVEVEVEVEVEVEVEVEVEVEVE-VEVEVEVE-VEVEVEVVELEVEV
|... |.. ......|. .. ...||.... | ||| ....| ..  ... |||. .. ........|... .  ....|.| .. ..|... ..|.
aglkvevkldvspslpe.fsniqlevkikpsvsvevvavmgvdtp.faqagvevksnlhsstplkikvkldakknkfklelelpqekkeiisvsset
subfamily_pats1_pd Subfamily pats1 118-202 2.1e-07 21.7 In-house 4-90 (691) alignment 
Range on Protein: 118-202
Range on HMM: 4-90/691.0
DGWALYSPMAEYGRMGVPNPQ-WQQVDYNNtYNLCPTYGRTLYLPSSVTMEQAFASAKFRSkQRLPVLSYLFQRNQAA---ICRCAQPL
. .  ||.. |. |...   . |. |.. .  .|.  | ..  .| .|. |   .... || ...||||.  | |...   ||   ||.
eifdiyslliegqrlkldldkdwrvvefls.rdlseiyPkrilvPklvsdellvsyvrkrs.skiPvlswsnqnnksslfricvynqpf
0045098 (Phosphotyrosine protein) phosphatases II 295-345 4.6e-07 25.0 In-house 161-227 (278) alignment 
Range on Protein: 295-345
Range on HMM: 161-227/278.0
QIGIQECAWLKHI--QAVLKTTMVITRYIQ--------------DGHSVLVHCSDGWDRTAQTCSLA
 ... .  .  .   . .|. .  | ....              .|. |||||| |..||.  . . 
ylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaay
0044763 (Phosphotyrosine protein) phosphatases II 291-344 6e-07 24.8 In-house 76-130 (178) alignment 
Range on Protein: 291-344
Range on HMM: 76-130/178.0
CHDHQIGIQECAWLKHIQAVLKTTMVITRYI-QDGHSVLVHCSDGWDRTAQTCSL
.. ..|.|        .. .|...  | ... ..|. |||||| |..|..  . .
iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaa
DUF1943 Domain of unknown function (DUF1943) 715-794 6.5e-07 14.8 Pfam-A 196-274 (302) alignment 
Range on Protein: 715-794
Range on HMM: 196-274/302.0
ELELEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEVEvEVEVEVEVLLELELELELEVEVEVEV
|| |.  . . ..|||...|. ...   ....||.... | ||| ....| ..  ... |||  .| ....|...|... 
elslkgaavaglkvevkldvspslpefsniqlevkikpsvsvevvavmgvdtp.faqagvevksnlhsstplkikvklda
0048179 (Phosphotyrosine protein) phosphatases II 290-345 9.4e-07 24.2 In-house 49-104 (144) alignment 
Range on Protein: 290-345
Range on HMM: 49-104/144.0
PCHDHQIGIQECAWLKHIQAVLKTTMVITRYIQDGHSVLVHCSDGWDRTAQTCSLA
 .. .....       ... .|..   | .....|. |||||| | .||.  . . 
giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaay
0048076 (Phosphotyrosine protein) phosphatases II 291-344 1e-06 24.0 In-house 48-101 (145) alignment 
Range on Protein: 291-344
Range on HMM: 48-101/145.0
CHDHQIGIQECAWLKHIQAVLKTTMVITRYIQDGHSVLVHCSDGWDRTAQTCSL
.. .....  .     .. .|.    | .....|. |||||| | .||.  . .
iqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa
0049772 (Phosphotyrosine protein) phosphatases II 261-344 1.8e-06 23.4 In-house 156-232 (314) alignment 
Range on Protein: 261-344
Range on HMM: 156-232/314.0
CRLEFHGIENIHtmrgslnalvkaS------KRNSP-CHDHQIGIQECAWLkHIQAVLKTTMVITRYiQDGHSVLVHCSDGWDRTAQTCSL
. . .. .|...            .      .   .  . ..| .    .   .. ...   .| .. ..|. |||||..|..||.  . .
neptaadlellk............eelydpelferlgikylripvpDgsap.lledfdeflefieea.dkggpvlvHCkaGkgRtgtfvva
0051429 (Phosphotyrosine protein) phosphatases II 314-422 1.9e-06 23.3 In-house 140-241 (272) alignment 
Range on Protein: 314-422
Range on HMM: 140-241/272.0
TMVITRYIQDGHSVLVHCSDGWDRTAQTCSLAGLMLDPYYRtiegyivLIEKEWLSFGHKFLDRNGFLKGSGREVSPIFLQLLECTWCLQRQFPLAFEFN
   . ....||. |||||| |.|||.  . |  |.|.  .         | ...| . .  ..    |.   . . .   |.| .  .|.  .   .. .
llellellldggpvlvHCsaGkdRTGtvvallllllgvsle.......tivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvr

ESFLIAMHD
...|.|..|
aeyllaald
subfamily_MTMR14_pd Subfamily MTMR14 307-377 2.7e-06 18.4 In-house 252-327 (357) alignment 
Range on Protein: 307-377
Range on HMM: 252-327/357.0
IQAVLKTTMvitRYIQ-DG-HSVLVHCSDGWDRTAQTCSLAGLMLD------PYYRTIEGYIVLIEKEWLSFGHKFLDR
 |  || ..   .|.. |.   .||||  |||||    ||  | |          ...|   . .  .|. |||.. ||
tqnylklll...kyvkededsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdr
subfamily_MTMR5_pd Subfamily MTMR5 128-201 3.2e-06 18.2 In-house 13-93 (483) alignment 
Range on Protein: 128-201
Range on HMM: 13-93/483.0
EYGRMGVP-------NPQWQQVDYNNTYNLCPTYGRTLYLPSSVTMEQAFASAKFRSKQRLPVLSYLFQRNQAAICRCAQP
.| |.|.        . ...    |..|..| .|   . .||.|  ..    ||   ..||||  .  .||.| . | ...
dykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
0046846 (Phosphotyrosine protein) phosphatases II 291-358 4.5e-06 22.1 In-house 77-142 (176) alignment 
Range on Protein: 291-358
Range on HMM: 77-142/176.0
CHDHQIGIQECAWLKHiQAVLKTTMVITRYIQDGHSVLVHCSDGWDRTAQTCSLAgLMLDPYYRTIEG
.. ..... .     . ...|.    | .....|. |||||| |  ||.  . .  |.   .  ..| 
iqylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay.llelekglsvee
0049260 (Phosphotyrosine protein) phosphatases II 292-345 5.2e-06 21.7 In-house 56-110 (152) alignment 
Range on Protein: 292-345
Range on HMM: 56-110/152.0
HDHQIGIQECAWLKHIQAVLKTTMVITR-YIQDGHSVLVHCSDGWDRTAQTCSLA
. ... .    . ...| .|    .| . ....|. |||||| | .||.  . . 
qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaay
0042113 (Phosphotyrosine protein) phosphatases II 288-344 6.7e-06 21.2 In-house 138-196 (245) alignment 
Range on Protein: 288-344
Range on HMM: 138-196/245.0
NSPCHDHQIGIQECAWLKHIQAVLKTTMVITRYIQ--DGHSVLVHCSDGWDRTAQTCSL
   .| |.... .     ... .|.    . ....  ... ||||||.| .||.  . .
revihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaa