Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 13-267 | 1.8e-110 | 363.2 | In-house | 5-263 (270) | alignment | ||
Range on Protein: 13-267
Range on HMM: 5-263/270.0
DMALVSKKRIPP--GTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGRE
| .|.. .| ...||||..|||.|.|||||..|..|..|.|||||||.|.||.. .|||..||.|||. .||||.||.....|||.|||.||||.
dkeetsesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrk
KCARYWPTvlfnEREGLGDMQAGFVNVAVLAGVRSNGYIATKLRIKhDKSDTERIVmHYWFNSWPDHGVPSETG------NVVKMLQAVREWSDDPER--
||.||||. |.. ....|...|..|. ....|||.|.||.. .|....|.| |.|.|.|||||||.|.. ...|||.|||..... ..
kCerYWpa....epkekvkledgkikvlalseekeegyiltrlrle.ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkae
PWIVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|..||||||||||||.|..||..|||.|.....|..||..|||||.|.||||||.||.||...||
PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavvey
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 8-267 | 1.1e-87 | 290.0 | In-house | 28-280 (564) | alignment | ||
Range on Protein: 8-267
Range on HMM: 28-280/564.0
EYNAIDMALVSKKRIPPGTSN--LNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQ
||. |.. .... | |||.||.. ..||.|||.. |. . ||||....||. .. .|||||||...|. |||||||| | ..|||.| |.
eykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqgPlaetiedFWRmvweqnsstiVmltkle
EKGREKCARYWPTVlfNeREglgdmQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWI
|||..||..|||. . .| . | . | . . .. . |. .....|. ||. | | .. | |||||||| .. ....... ||... . . |..
EkgkvkchkYWPek..g.te.....tygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPiv
VHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
||||||||||||||.||. .. ..| . .. .....|||.| |||| .|| | .... |.
VhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailea
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 24-267 | 1.4e-83 | 276.0 | In-house | 47-285 (288) | alignment | ||
Range on Protein: 24-267
Range on HMM: 47-285/288.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNE
| . ||| .|||. ..||.|| |.... ..||||.|..||. . .||||||.|.|. |||||||| | . |||.|.|.|.||||||.|||. ..
penleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl...gg
REGLGDMQAGFVNVAVlagvrSNGYIATKLRIKHD----KSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFI
. .||.. .... | ..|. ..|.... .....|.|.|... .|||||||. . ....|..||.. ... | .||||||||||||||
sltygditvtllseev.....lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfi
TIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
..|. ...|...|...| |...|||. |. ||| ||| .| |..| ||
aldllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 25-267 | 5.5e-83 | 274.1 | In-house | 67-298 (308) | alignment | ||
Range on Protein: 25-267
Range on HMM: 67-298/308.0
GTSNLNRYNNILPNPRTRVRLsklndDDITTYINANYVHGYD-GAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNE
..||| .|||. ..||.| |. ..||||.||.||. . ..||||||.|.|. |||||||| | . |||.| |.|.||||||.|||. | ..
enkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelggg
REGLGDMQAGFVNVAVlagvrSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSddPERPWIVHCSAGVGRTGTFITIDI
. |... .... | ..|. ..|.... ... .|.|.|... .|||||||... ....|..||.. |. | .||||||||||||||..|.
sleygkftvtllseev.....lddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdl
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
...|.. |...| |....||. |. ||| ||| .| |..| ||
lleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralley
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 24-267 | 8.6e-83 | 273.3 | In-house | 26-273 (284) | alignment | ||
Range on Protein: 24-267
Range on HMM: 26-273/284.0
PGTSNLNRYNNILPNPRTRVRLSKLNDD-DITTYINANYVHGYD----GAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPT
| ..||| .|||. ..||.|. |..| . ..||||.||.||| . ..||||||.|.|. |||||||| |.. |||.|.| |.||||||.|||.
penlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwpl
VlfNEREGLGDMQAGFVNVAVlagvrSNGYIATKLRIKHDK-SDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSD--DPERPWIVHCSAGVGRT
.| .||.. .... | ..|. ..|.... . .. .|.|.|... ||||||||... .....|..|||. . ... | .||||||||||
e..gevltygdftvtllseev.....kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRt
GTFITIDIGMRLLQERG---RCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
||||..|. ...|...| ...| |...|||. |. ||| .|| .| |..| ||
GtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealley
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 26-267 | 3.6e-79 | 261.6 | In-house | 43-275 (317) | alignment | ||
Range on Protein: 26-267
Range on HMM: 43-275/317.0
TSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNERE
..||| .|||....||.|| |. | ..||||.||.|.. . .||||||.| |. |||||||| . ..|||.| | |.||||||.|||. .|
nkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrk.fIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwpl...getl
GLGDMQAGFVNVAVlagvrSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGM
||.. .... . .|.. ..|..........|.|.|... .|||||||. . ....|.||||. .||. | .||||||||||||||.... .
tygdftvtllseee.....lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylml
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
..|...|...| |....||. |. .|| ||| .| |..| ||
eqlekeggvdveeavkelreqRpgavqtpeqyrflydalley
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 7-267 | 7e-79 | 259.8 | In-house | 9-267 (274) | alignment | ||
Range on Protein: 7-267
Range on HMM: 9-267/274.0
EEYNAIDMALVSKKRIPPGTSNLNRYNNILPNPRTRVRL-SKLNDDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQ
.|. . . .. .|... |||..||||...|| | |. ..|. ..||||||..|||. . .|.||||| |.| |||||....... |||.| |.
keflelPlnfdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklk
EKGREKCARYWPtvlfnE-REGLGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSdtERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPER--
|. ..|||.|.| . .. . . | |.. | |. |.| .|| .|. .. || |.|||. .|||| .| .. ....... |.| .. .
eaneqkCavyfP.....daedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenakl
-PWIVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
| .||||||.|||| ||.|.|..| |.|.. .| .|. || || ||| || |. ...|..|
apvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly
|
|||||||||
| DSPc_SM00195 | 25-267 | 3.5e-77 | 254.6 | In-house | 25-261 (263) | alignment | |||
Range on Protein: 25-267
Range on HMM: 25-261/263.0
GTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYdGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNER
.. |||.||||. .|||.|.| .... ..||||||. |. .|||||||.|.| ||||||||.. . |||.| .|.|.|||.|||| ..
knksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpees.ggk
EGLGDMQAGFVNVAVLAgvrsNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIG
| |... .|.| . .| ..|...... ...| | .|....|||||||..| .|...|.||..... . | .|||||||||||||.||||
etfgkisvklvevekkk....deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.. |.| . .. ||...||| |. ||| || |.|... ||
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| PTPc_SM00194 | 25-267 | 3.5e-77 | 254.6 | In-house | 25-261 (263) | alignment | |||
Range on Protein: 25-267
Range on HMM: 25-261/263.0
GTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYdGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNER
.. |||.||||. .|||.|.| .... ..||||||. |. .|||||||.|.| ||||||||.. . |||.| .|.|.|||.|||| ..
knksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpees.ggk
EGLGDMQAGFVNVAVLAgvrsNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIG
| |... .|.| . .| ..|...... ...| | .|....|||||||..| .|...|.||..... . | .|||||||||||||.||||
etfgkisvklvevekkk....deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.. |.| . .. ||...||| |. ||| || |.|... ||
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 24-267 | 1.4e-76 | 252.8 | In-house | 36-271 (273) | alignment | ||
Range on Protein: 24-267
Range on HMM: 36-271/273.0
PGTSNLNRYNNILPNPRTRVRLsklnDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNE
| ..||| .|||. ..||.| .|. . ||||.|| ||. . .||||||.| |. |||||||| |.. |||.| |.|.||||||.|||. .
penkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrk.fiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggel
REGLGDMQAGFVNVAVlagvrSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVGRTGTFITI
. |... .... . ..|. ..|.... ... .|.|.|... .|||||||. . .......||.. . | .||||||||||||||..
sltygkftvtllseet.....kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfial
DIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|. ...|...|. .| |....||. |. ||| ||| .| |..| ||
dllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 9-267 | 2.1e-76 | 252.0 | In-house | 26-279 (318) | alignment | ||
Range on Protein: 9-267
Range on HMM: 26-279/318.0
YNAI---DMALVSKKRIPPGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQ
|... . | | . | . |||.|||. .|||.|..|... . ||||||. || .. .|||.|.| | | .|||||||| |. |||.| ..
yerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyr.rkkayiaaqaPlpetieDfWrmvWeqnsavivmltqee
EKGREKCARYWPTvlfneReglGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWS-DDPERPW
|.|..|..|||| . | .. | . | . |... |. .......... .|.| | . ||||.|||........... |... . ..|
ergkakvhryWPs.....k...gsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpi
IVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.|||||||||||.||..|| .. ... . .| .....||. | .||| .| || |.|| |.
vvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllea
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 24-267 | 6.4e-76 | 250.8 | In-house | 37-276 (297) | alignment | ||
Range on Protein: 24-267
Range on HMM: 37-276/297.0
PGTSNLNRYNNILPNPRTRVRLsklnDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNE
|.. ..||| .|||...|||.| ||. . ||||.|| ||| . .||||||.|.|. |||||||| | ..|||.| | |.||||||.|||. ..
penleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrk.fIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleeges
REgLGDMQAGFVNVAVLagvRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVGRTGTFITI
. ||.. ...| | ...|. ..|.... ... .|.|.|... .|||||||. . .......||.. . .. | .|||||||||.||||..
lt.ygdftvtllsvevv...llddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaa
DIGMRLLQ---ERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|. ...|. ..|.... |... ||. |. .|| .|| .| | .| |.
dlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 26-262 | 2e-75 | 248.6 | In-house | 51-279 (293) | alignment | ||
Range on Protein: 26-262
Range on HMM: 51-279/293.0
TSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfnere
.. |||.|||| .||.|..|.|.. . ||||||..|| . .|||||| |.|. ||||||||.... |||.| | |||..|| .|||.
nraknrytnilpydhsrvkLaalkdesgsDYinanyipgynspr.efiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPad......
gLGDMQAGFVNVAVLAGVRSNGYIATKLRIKHdkSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWS--DDPERPWIVHCSAGVGRTGTFITIDI
... | ..| ..| . . .. .|.|.. ...|| |..| | ||||||||..| ........|||. . .|| .||||||||||||||..|
.eepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdr
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYK
.. ..|. .. |. .||..|. .|| .| | ..
llqaieeedyvdifgivaelReeRnllvqtekqYifihq
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 24-267 | 3e-75 | 248.6 | In-house | 43-276 (278) | alignment | ||
Range on Protein: 24-267
Range on HMM: 43-276/278.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfNE
| ..||| .|||....||.|| |. | ..||||.|| ||. .. .||||||.| |. |||||||| . ..|||.|.| |.||.|||.||| ..
penkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprk.fiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp....gg
REGLGDMQAGFVNVAVlagvrSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
. ||.. .... . ..|. ..|.... ... .|.|.||.. .|||||||. . ....|.||||. .|.. | .||||||||||||||....
sltygdftvtllkeeh.....lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyl
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
...|. .|. .. |....||. |. .|| |.| .| |..| ||
lleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 27-267 | 2.7e-74 | 245.6 | In-house | 57-288 (297) | alignment | ||
Range on Protein: 27-267
Range on HMM: 57-288/297.0
SNLNRYNNILPNPRTRVRLSKLND-DDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGReKCARYWPTVLFnere
..||| .|||....||.|. ... | ..||||.|| ||| ..||||||.| |. |||||||| . ..|||.| | |.|| |||.|||.
kdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg....
glgdmQAGFVNVAVLAGVRSNGYIATKLRIKHdkSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVGRTGTFITIDI
. | . | .| .||. ..|.... .. .|.|.|... .|||||||. . . ..|..|||. ...| .||||||||||||||....
.....tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaayl
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
...|...|. .| |....||. |. .|| |.| .| |..| |.
mleqlekeggvdvleavkelreqRpgavqtpsqyrflydallel
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 26-267 | 6.5e-74 | 244.7 | In-house | 55-303 (307) | alignment | ||
Range on Protein: 26-267
Range on HMM: 55-303/307.0
TSNLNRYNNILPNPRTRVRLSKLNDD-DITTYINANYV--------HGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYW
..||| .|||...|||.|| |... . . ||||.|| .||| ..||||||.| | |||||.|| . . |||.|.| |.||||||.||
nkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydl.krkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqyw
PTVlfNEREGLGDMQAGFVNVAVlagvrSNGYIATKLRIKHD-KSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVG
|. .| |... .... . .||. ..|.... ... .|.|.|... .|||||||. . .......||.. .. .. | .||||||||
Pde..geeltygnftvtllseeh.....ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvg
RTGTFITIDIGMRLLQERGR---CNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
||||||.... .|.|...| ... |....||. |. .|| ||| .| |..| |.
RtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 28-265 | 2e-73 | 242.0 | Pfam-A | 3-234 (235) | alignment | ||
Range on Protein: 28-265
Range on HMM: 3-234/235.0
NLNRYNNILPNPRTRVRLSKLND-DDittYINANYVHGYDgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfNEREG
. |||..||| .|||.|.. .. | |||||||.||. . ..||||||.. | |||||||. . ..|||.| |.||||||||.||| .|.|.
kknRykdilpydktrvklkgsegpsd...YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwp....eeeee
LGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDT-ERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGM
. .|.. . ...|. .||..|..|... .|.|.......|||||||... ........|...... . | .|||||||||||||...|| .
sltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLS
. |.... .| .|...||| |. ||| || .| ||..
eqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 28-265 | 2e-73 | 242.0 | In-house | 3-234 (235) | alignment | ||
Range on Protein: 28-265
Range on HMM: 3-234/235.0
NLNRYNNILPNPRTRVRLSKLND-DDittYINANYVHGYDgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfNEREG
. |||..||| .|||.|.. .. | |||||||.||. . ..||||||.. | |||||||. . ..|||.| |.||||||||.||| .|.|.
kknRykdilpydktrvklkgsegpsd...YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwp....eeeee
LGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDT-ERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGM
. .|.. . ...|. .||..|..|... .|.|.......|||||||... ........|...... . | .|||||||||||||...|| .
sltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLS
. |.... .| .|...||| |. ||| || .| ||..
eqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 24-267 | 3e-72 | 238.2 | In-house | 40-289 (297) | alignment | ||
Range on Protein: 24-267
Range on HMM: 40-289/297.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfnE
.. .. |||...| .||| |.|...|. . |||||.| || . ..|||||| . |. |||||||| .. |||.| . |.|| ||..|||. |
ranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykq.kkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpl....e
REGlgDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVRE------------WSDDPE-RPWIVHCSA
.| .. |...|... . .. | ..| ||. | . .| |.|. | ||||.||||.. .....|..||| | .|. | .|||||
ees..saefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsa
GVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|.||||||||.|| . |.| | ..| | ...||. | ..| ||| || |. . ||
GiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 27-267 | 9.6e-72 | 236.8 | In-house | 12-245 (249) | alignment | ||
Range on Protein: 27-267
Range on HMM: 12-245/249.0
SNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNEREG
..||| .|||....||.|| |.. . ||||.|..||. . .||||||.| |..|||||.|| . ..|||.| |.|.||||||.|||. ..
kdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl...ggsle
LGDMQAGFVNVAVlagvrSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVGRTGTFITIDIG
||.. ...| | ...|. ..|.... . ...| |.|... .|||||||. . ......|||.. .. .. | .||||||||||||||....
ygdftvtllsvev.....kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
...|..... .. |... ||. |. .|| ||| .| |..| |.
leqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 27-267 | 1.4e-71 | 236.1 | In-house | 10-242 (245) | alignment | ||
Range on Protein: 27-267
Range on HMM: 10-242/245.0
SNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNEREG
..||| .|||...|||.|| . | ..||||.||.||. .. .||||||.| |..|||||.|| . ..|||.| . |.||.|||.|||. .|
kdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl...geslt
LGDMQAGFVNVAVlagvrSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSD-DPERPWIVHCSAGVGRTGTFITIDIGM
||.. .... . ..|. ..|.......| .| |.||.. .|||||||. . ....|..||.. |.. | .||||||||||||||.... .
ygdftvtllseeh.....lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
..|..... .. |....||. |. .|| |.| .| |..| |.
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 24-267 | 2.1e-71 | 235.6 | In-house | 46-282 (319) | alignment | ||
Range on Protein: 24-267
Range on HMM: 46-282/319.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFne
. .. |||.|||. |||| ||.|.. . ..||||... ||. . .||||.| .|. |||||||| .. .||.|.|.||.. |. .|||. |
eenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqe.rekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenf..
reglgdMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDT-ERIVMHYWFNSWPDHGVPSETGNVVKMLQAVRE-WSDDPERPWIVHCSAGVGRTGTFITI
.. | . | .. . ..|| || ... .|. | |.|. ...||||.|| .. ....|. .|. .. ..| .||||||||||||||..
......eeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivl
DIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|. . ..| | .| ....||| | |||.||| .| |..| |.
damlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyeallea
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 24-267 | 3.2e-71 | 235.2 | In-house | 31-271 (278) | alignment | ||
Range on Protein: 24-267
Range on HMM: 31-271/278.0
PGTSNLNRYNNILPNPRTRVRlsklnddDittYINANYVHGYdgaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNE
.| ..||| .|||....||. | ||||.|..|| . ..||||||.|.|. |||||.|| . ..|||.|.|.|.||||||.||| ..
lgnldknRykdilpydhsrVk.......d...YINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe...gg
REGLGDMQAGFVNVAVLagvrsNGYIATKLRIKHD----KSDTERIVMHYWFNSWPDHGVPSET--GNVVKMLQAVREWSD-------------DPERPW
. ||.. .... || . |. ..|.. . .....| | |... .||||||||.. . ..|. .||. . |.. |
sltygdftvtllseevl.....ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv
IVHCSAGVGRTGTFITIDIGMRLLqErGRCNVNEIIRRLRKDRCA-MVQHPEQAEFAYKVLSEY
.||||||||||||.. ... ..|| | |.... |... ||. |. .||..|| .| |..| |.
lVHCsaGvgRtGtlvaaylmlell.e.ggvdlleavkelrsqRpglavqnleqyrflyefllel
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 27-267 | 8.4e-69 | 227.1 | In-house | 11-241 (243) | alignment | ||
Range on Protein: 27-267
Range on HMM: 11-241/243.0
SNLNRYNNILPNPRTRVRLsklndDDiTTYINANYVHGYDgahgTYIATQGPTPTTTPD----FWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfn
. ||| .|||....||.| .. . |||||.. ... ..||||||.| |. | ||||.|| . ..|||.| |.|.||||||.|||
lsknrysdilpydhsrvkl.....eg.sdyinanliyvtp....rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp.....
ereglGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDK-SDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREW--------SDDPERPWIVHCSAGVG
|... | . | .| ..|. ..|.... . .| .| |.||.. .|||||||... .....|..|||. .|...| .||||||||
.....gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTGTFITIDIGMRLLqergRCNVNEIIRRLRKDRCA-MVQHPEQAEFAYKVLSEY
||||.|.... ..|| .... |....||. |. .|| |.| .| |..| |.
RtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 26-267 | 1.4e-68 | 226.1 | In-house | 54-296 (306) | alignment | ||
Range on Protein: 26-267
Range on HMM: 54-296/306.0
TSNLNRYNNILPNPRTRVRLSklNDDDI-TTYINANYVH-GYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNE
. |||.|||| ||| |. ... . ..||||||.. | . .|||||| .|| .|||||||. |.. |||.| |.|.||||||||.. .|
nkeknryknilPfDhtrvilk..epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeeke
RegLGDmqagfVNVAVLAGVRSNGYIATKLRIKH-DKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPE----RPWIVHCSAGVGRTGTF
. |. ..| .. . . || .|.... .|...|| |..| |.||||||||...| |...|. |.. ... | .| .||||||.||||||
e..yGk.....isvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtf
ITIDIGMRLLQERG---RCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
| ||| ..|....| ........ .|. | .|| .| | ||....|
iviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikky
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 27-267 | 3.2e-68 | 225.1 | In-house | 47-282 (305) | alignment | ||
Range on Protein: 27-267
Range on HMM: 47-282/305.0
SNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAhGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNEREg
. ||...| . . |..|.. ...| . ||||.||.||.. .||..||| ..| ||||...|. ..|||.|.|.| |..|| .|||. ...|
kaknrlkeitlldddriiltekeslddsdyinasyvdgykrk.kkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekke.
LgdmqaGFVNVAVLAGVRSNGYIATKLRIKH-DKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVR-EWSDDPERPWIVHCSAGVGRTGTFITIDIG
. | ..| . ..|| ||.| |... .| |..| . .||||||| ... ...... |. ... | . | .|||||||||||.||..||
f.....gefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdia
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. |.. . .| |....||. | ||| .| | . .| |.
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldel
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 11-266 | 6.9e-68 | 223.8 | In-house | 26-274 (281) | alignment | ||
Range on Protein: 11-266
Range on HMM: 26-274/281.0
AIDMALVSKKRIPPGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGRE
||.. ... . . |||.|| |||.... ... | |||||.| ||.| . ||||||| |.. .||.||||.... ||||| |.|.
aigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgek.eyiatqgPvPaslvafWqmvweqkvsaivmvtreieagkl
KCARYWPTVLFnereglgDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDtERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSD-DPERPWIVHCS
|| |||| ... | | | .| ... || |......... .| | . . .|||||||..| .... ..|.. .. . . | ..|||
kChrYWPddns.......elkygdvtvkstaeeekatyierkfkleresge.treveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCs
AGVGRTGTFITIDIGMRLL-QERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
||||||||.|..| .. . .|. . .|..... |||.| ||| | || ||.. .
aGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavld
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 28-267 | 2.9e-67 | 221.9 | In-house | 60-294 (330) | alignment | ||
Range on Protein: 28-267
Range on HMM: 60-294/330.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNEREGL
. ||. ||||. .|| ||... . . |||| ...|| ..||.||| | |||||.|| .. .|||.| |.|. .||||.|||. .
eknrvvnilPydfsrvilsvkeGveesdyinasfidGyke.kdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPd...eGlvty
GDMQAGFVNVAVLAGVRSNGYIATKLRiKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRL
|... .. || . .. ..| .. . ...|.| . |.|||| |||.|. ..|.|..|.. . | .||||||||||||||..| .
Gnirvevedetvlvdytvrkflvqqlp.datrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavler
LQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.. .. .| |...|||. |. ||| || || |||| ||
vkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 26-266 | 2.5e-66 | 218.5 | In-house | 40-275 (290) | alignment | ||
Range on Protein: 26-266
Range on HMM: 40-275/290.0
TSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNERE
. . ||| .||| .|| ||| .... |||||...| .| . .|||.||| |.| |||||.||.| . .||. . | |. ||.|||| .|.
nvkknrykDilPydksrvelskieeeegsdYinanfikgvegkl.eyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeeg.eeel
GLGDMQAGFVNvavlAGVRSNGYIATKLRIKHDksDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGM
|... . ..... |..... ...|.| . ...|||||||| . ........||| .. . | .|||||||||||| |.||.
efgefevtlee....ekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvr
RLLQERGR---CNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
.||... .| .....|||.| |.|| || |. || . |
ellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 26-264 | 5.5e-66 | 217.6 | In-house | 37-265 (273) | alignment | ||
Range on Protein: 26-264
Range on HMM: 37-265/273.0
TSNLNRYNNILPNPRTRVRLSKLNDddittYINANYVHGYDG-AHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNER
. ||| |.|| .|||.|.. ||||.... | . .|||.||| |.|. |||.|||| .|. |.||| .|||. || |||| ..
nkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkkl
eglgdMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDdPERPWIVHCSAGVGRTGTFITIDIG
. . ..|..| .. .|. .| .|. .| | |.| | .||||||||.. ....... ||. . . | .||||||.||.||.||||.
.....kvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidvv
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVL
. |.. .|.||.|.||. | ..|| .| | ||..
lglierdkefdvkeivrklreqrqgvvqtkdqyifvykai
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 24-264 | 7.5e-66 | 217.1 | In-house | 45-275 (288) | alignment | ||
Range on Protein: 24-264
Range on HMM: 45-275/288.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfNE
. . |||.|||| .||.| ||.. . . ||||.|..|... . .||||||| . | |||..|.|.... |||.|.| |.|..|| .|||. ..
avnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekk.kkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPda..dk
reglgDMQAGFVNVAVLAGVRSNGYIATKLRIKhdKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
. | |.| .. . .. || .. |. ||. . .| . .||||||| . .....|. | ... | |||||||||||||||..|
.....pknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialda
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVL
. ..| .| ... .||| | .|| .| || |.||
lidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 26-266 | 2.8e-65 | 215.6 | In-house | 47-285 (563) | alignment | ||
Range on Protein: 26-266
Range on HMM: 47-285/563.0
TSNLNRYNNILPNPRTRVRLSKLNDDDIT-TYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNER
. ||| ||.. |.||.||.| . . . ||||||..|| .. .|||||| ..|. |||||.|| |.. |||.| |.|.||.|| .|||. .|
nkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqksk.afiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk...des
EGLGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKS-DTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
| .| .| .. ||| .. . .|..|. |. |||. |..| . .|||||||. . |... . . | .||||||||||||.| .|
etygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldt
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
.. .|.. || ......| | .|| || | ...| |
llkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalle
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 27-267 | 3.1e-65 | 215.4 | In-house | 57-289 (298) | alignment | ||
Range on Protein: 27-267
Range on HMM: 57-289/298.0
SNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfnereg
. ||| .|.. .||.|.| ..|....|||| ..|.|.| . ..||||.| ..|. ||||||.| ....|||.| |.|... |. .|||..
kkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn.afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPde.......
lGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPE-RPWIVHCSAGVGRTGTFITIDIGM
| . | ..| .|. . .| .|| ... |...|| | . | ||||.|||... |...|. || . . .| ||.|||||||.|||| || .
.gketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvl
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
... | .....|||.|...|| || | |.. |.
ervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlea
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 26-266 | 1.5e-62 | 206.2 | In-house | 43-275 (314) | alignment | ||
Range on Protein: 26-266
Range on HMM: 43-275/314.0
TSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfNERE
. ||...||. |.||.| ...| . ||||... .| .. .|.|||| . |. ||||.|.. |. ||||.| |.|.|| || .||| .. |
nreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpa.afivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWP....edte
GLGDMQAGFVNVAVLAGvrsngYIATKLRIKH--DKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
||.. .|.. .|| ... .|... . . |.| .. | .||||.|| . ..|... | ..... . . .|||||| |||||||.|||
vygdikvelvetellae.....lvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidi
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
. .....| .| .... ||. . ||. || | | |. |
vldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 26-267 | 1.4e-61 | 202.9 | In-house | 9-241 (250) | alignment | ||
Range on Protein: 26-267
Range on HMM: 9-241/250.0
TSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAhGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREkCARYWPTvlfNERE
. ||| .|.. .|| | | . |... |||| ..||||. ..|||||| ..|. ||||||.| ....|||.| |.|.... . .|||. .. |
nkeknryadiialdssrvvLekekgdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv...ekae
glgdmQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD-PERPWIVHCSAGVGRTGTFITIDIG
. | | | .| |. .|| . . | |||| .. | .||| ||| .. |...|. |. . ..| ||.|||||||.|.||.||
.....kyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidav
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. |.. .| ..|..||||| .|. || | |... ..
lerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 27-260 | 1e-60 | 200.0 | In-house | 42-267 (280) | alignment | ||
Range on Protein: 27-260
Range on HMM: 42-267/280.0
SNLNRYNNILPNPRTRVRLSKLNDDdittYINANYVHGY-DG--AHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlFNE
. ||| .||| |||.|.. . | ||||||| .. . ||||||| ..|. |||.|||| ... |||.| | |.|| || .|||. ..
lsknryrdilpydatrvklkesetd....yinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe..ted
ReglgdMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
. .. | .| . ... |. .| .|. ... || ... . .|||||||... ....... ||. |.| .||||||.|||| .|....
e.....leygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlillet
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFA
. |.... .. .|.|..| | ..|| ..| .|
alalieaaepvypldivrtmrdqramlvqtasqykfv
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 30-267 | 1.2e-60 | 200.2 | In-house | 52-285 (307) | alignment | ||
Range on Protein: 30-267
Range on HMM: 52-285/307.0
NRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAhGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfnereglGD
|||..| . .|||.|.|.| .. ..||||....||. ..|| |.| .| |||||..| . . |||.. |.|| |.|||.|||
nRyedikafDktRvkLkkingkedsdYinasfikgykek.kkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie........de
MQAGFVNVAVLAGVRSNGYIATKLRIKHDK-----SDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIG
.| | ..| . . . || .| . . | . .| |. | ...|.| || . ..|... ||| . | .|||||||||.|.|...|.
vqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsl
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. |.. . .. |... ||..| .|| || .| |. | .|
lqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldy
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 28-267 | 2e-59 | 196.0 | In-house | 46-276 (315) | alignment | ||
Range on Protein: 28-267
Range on HMM: 46-276/315.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfnEREGl
. |||.|||| ..||.| ..|. |||| |....| .|||.||| ... ||||||..... .||||| .|| . ||..||| .|..
kknryknilPldsarvkleviddsPdsdyinasyiksvdd.dkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywP.....drka.
GDMQAGFVNVAVLAGVRSNGYIATKLriKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRL
.. | ..|..| . .| || ||.. | | . |. |||.||. .|. ..|....|. . | . .||||||||||| .|.|| .
dsvefGsikvellsleadtdgvarkl..vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaq
LQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.... .| .... ||..| .|| |. | | .. |.
ikrtrsvdvfnfvknlrakrpylvqteeeyafiydavled
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 29-267 | 4.2e-59 | 195.0 | In-house | 46-275 (515) | alignment | ||
Range on Protein: 29-267
Range on HMM: 46-275/515.0
LNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNereglg
|||.|||| ..||.| .||. |.|| |....| .|||.||| .... ||||.|.. | |.||| |.| . ||..||| . .
knryknilPydsvrvklevindnPhsdyfnasyipsfdn.dkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgd......
DMQAGFVNVAVLAGVRSNGYIATKLRIKhdKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRLL
.. | ..| ... | | ||.. |.| | | . |. |||.||| .| ..|....|. . . | |.|||||||||| .|.|| .
svkfGsikvelvsleactggikrkltvl..kgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvaha
QERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.. .| .... .|..| .|| || | | .. |.
kttrmvdvfnfvtnirqkrpylvqtqeqyafiygavled
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 16-267 | 6.7e-57 | 187.9 | In-house | 44-283 (297) | alignment | ||
Range on Protein: 16-267
Range on HMM: 44-283/297.0
LVSKKRIppgTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGahgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGReKCARY
|..|.. . .||.|||| . ||.| .||| |.|| .|.|. .|.|| | ..| |||.||.. ... |||.. ..|. . |||||
tvaekkv...nfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh...rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcary
WPTVLFNEreglgdmqAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPS--ETGNVVKMLQAVRE-WSDDPERPWIVHCSAGV
|. .. | | | .|. . .|.| .| ....|. ..|.| | | .|||. |. .. ..|... ||. .|. | | .|||.|||
Wsdkgvtt........fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGv
GRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|||| ..||| . .. .. .....||..| .|| || .| |... |.
Grtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlea
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 28-266 | 8.5e-57 | 187.9 | In-house | 63-289 (319) | alignment | ||
Range on Protein: 28-266
Range on HMM: 63-289/319.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTglqekgREKCARYWPTVLfNEREGL
. ||. |||. ...|.| .|. . . |||| .| || . |||.||| . | |||||.|| |. .||..| ..||..||| ...|.
dknriinilafdknvvklerliGeefsdyinasfvtGyqr.kdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplki.vikeer
GDMQAGFVNVAVLagvrsngYIATKLRIKH-DKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSD--DPERPWIVHCSAGVGRTGTFITIDIG
.... |. . |. .... . | | . . | |||.||| . ....... || . . ... .|||||||||||..|..|.
fkvkvdsveetae.......yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvl
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
. ..| . .| ...| ||..| .||. | | | | |
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 28-266 | 2.5e-56 | 186.3 | In-house | 27-253 (284) | alignment | ||
Range on Protein: 28-266
Range on HMM: 27-253/284.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTglqekgREKCARYWPTVLfNEREGL
. ||. .||. ...|.| .| . . |||| .. || . ||||||| . | |||||.|| |. .||..| ..||..||| ...|.
dknrighilafdknvvklerliGeefsdyinasfitGyqr.kdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplki.vikeer
GDMQAGFVNVAVLagvrsngYIATKLRIKH-DKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVGRTGTFITIDIG
.... |. . |. .... . | | . . | |||.||| . ....... || .. ... .|||||||||||..|..|.
fkvkvdsveesee.......yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvl
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
. ..| . .| ...| ||..| .||. | | | | |
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 26-267 | 2.2e-55 | 182.8 | In-house | 49-295 (300) | alignment | ||
Range on Protein: 26-267
Range on HMM: 49-295/300.0
TSNLNRYNNILPNPRTRVRLSKLNDDdITTYINANYVHG-YDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNER
. ||....|| .||.|| ... | |||| .. |.. .||..||| ..| |||.||||.. . |||.| .|.|.||. .|.| ...
naeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkk
eglgDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVK---MLQAVREWSDDPE------RPWIVHCSAGVGRT
.. | .| |. .|.|.|..|| | || |.| .. |||||||.. . .. ..|.||. ... | .||||||||||
....tvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrt
GTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
| |. |. . |. . .......|||. | .|| | .| |||| .|
GvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvliky
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 27-264 | 1e-54 | 180.3 | In-house | 44-276 (288) | alignment | ||
Range on Protein: 27-264
Range on HMM: 44-276/288.0
SNLNRYNNILPNPRTRVRLSKLNDDdittYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNEREG
|. ||...||| ..|| | . .|| |||| .|.. ..||||.| ..| |||.||.| .. |||.. .|.|..|..||||. .| .
seknrsrdilPyDhnRvklrgskDD....YinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedk.getvk
LGDmqagfVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVRE----WSDDPERPWIVHCSAGVGRTGTFITID
|| ..|.. ... .. .|.... ..|. . |.| ..|||..|||. ......|..|.. . | .|||||||||||.| .
fgd.....lsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvy
IGMRLL-QERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVL
.| | .. | .. ....|||..| |||. || .|.|..
aavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 24-263 | 6.5e-53 | 174.3 | In-house | 30-266 (290) | alignment | ||
Range on Protein: 24-263
Range on HMM: 30-266/290.0
PGTSNLNRYNNILPNPRTRVRLSKLNDdditTYINANYVHgYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfNE
| ||||| .. | .|..| . . ||||. |. . |. || |||| | |. ||.|||| .. ..||. . ||.. |||.|||. .|
penrnlnryrdvspydhsrikleradn....dyinaslve.leeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqg..ee
REGLgDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWS--DDPERPWIVHCSAGVGRTGTFITI
. | .. ..| ... |.. |. .|... |.. | ..|. . .||| |||. .. .|.|. ||| . | ..|||||.||.|||. .
ekel.lledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclv
DIGMRLLQERGR---CNVNEIIRRLRKDRCAMVQHPEQAEFAYKV
| . |..... ..... . ||| | ..| ..| .|.|
dtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsyla
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 24-267 | 3.3e-52 | 172.2 | In-house | 44-282 (290) | alignment | ||
Range on Protein: 24-267
Range on HMM: 44-282/290.0
PGTSNLNRYNNILPNPRTRVRLSKLNDD-D-ITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlf
. ..|||..||... |. | ..... | |||| |..|| .. |||||||.. | |||...|. . |||.| .|.|..|| |||.
ssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekk.qyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..
NEReglgDmqAGFVNVAVLAGVRSNGYIATKLRIKHDKS-DTERIVMHYWFNSWPDHG-VPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFI
. . . | ... .| |.|| .||..|...| .....|..| . .|...| |. ... .. . . .. . ... .||||..|||...|.
dtk....a..ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfc
TIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
...... . | .| ......| . .|| .| .. .... .|
aaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlty
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 28-266 | 7.5e-52 | 171.2 | In-house | 51-277 (315) | alignment | ||
Range on Protein: 28-266
Range on HMM: 51-277/315.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfneregl
. ||| ||.. ..||.| |. |. . |.|||.. ||. . |||.||| ... ||||.|.| . |||.|.| |. ..|. .|||
qknryiniiaydksrvqlpllendphsdyvnanfidGynk.krryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk........
gDMQAGFVNVAVLAGVRSNGYIATKLRIKhdKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRL
.. | . |. . | | . | | |. . . |||| ||| | ..... . |. . .. . .|||||||||||||||.| .
.kviyGkitvtrkseevnteytvrtlsvv..fgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldq
LQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
.. .| ..|...|. | ||| || .| |..| |
aeaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 28-261 | 1e-49 | 163.8 | In-house | 9-233 (239) | alignment | ||
Range on Protein: 28-261
Range on HMM: 9-233/239.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfnerEGL
||| ||. ..|| | ||..| . ||||.|.. |||. .|||||| ... |||||.|. |||.||| | ..|| .|||
aknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst....sky
GDMQAGFVNVAVLAgvrsnGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRL
... . . |.| || . . . || | .| | |||.||| . |. . . . . | |||..||||||||||.|. || .|
cnlrvtlrktevfa.....dyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq
LQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAY
... .. . .. .|.|| ||| || | .
akkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 28-261 | 1.1e-49 | 163.8 | In-house | 10-234 (239) | alignment | ||
Range on Protein: 28-261
Range on HMM: 10-234/239.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfnerEGL
||| ||. ..|| | ||..| . ||||.|.. |||. .|||||| ... |||||.|. |||.||| | ..|| .|||
aknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst....sky
GDMQAGFVNVAVLAgvrsnGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRL
... . . |.| || . . . || | .| | |||.||| . |. . . . . | |||..||||||||||.|. || .|
cnlrvtlrktevfa.....dyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq
LQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAY
... .. . .. .|.|| ||| || | .
akkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 53-267 | 1.3e-49 | 164.5 | In-house | 3-224 (272) | alignment | ||
Range on Protein: 53-267
Range on HMM: 3-224/272.0
ITTYINANYVHGYdGA---HGTYIATQGPTPTTTPDFWRMvWETNANSIVMVTGLQEKGREKCARYWP----TVLFNEREGLGDMQAGFVNVAVLAGVRS
...||||..| || | |......||.| | ||||. .| . ..||..... |.||.|| |||| .| . .. .. |.. | .| .
lsgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
NGYIATKLRIKHD-KSDTERIVMHYWFNSWPDHGVPSETgnVVKMLQAVREwsddpERPWIVHCSAGVGRTGTFITIDIGMRLLQERGRCN--------V
. || ..|.... . .. | |||... .|||||||.|. ....|..... ..| .||||||..||||.. ... .. . . .. .
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
NEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|....||. | ..||..|| .| |..| |.
eeaveelraqrpgavqteeqylflyeallel
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 26-266 | 5e-49 | 161.8 | In-house | 47-276 (287) | alignment | ||
Range on Protein: 26-266
Range on HMM: 47-276/287.0
TSNLNRYNNILPNPRTRVRLSklndDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfneRE
..||...||. || | . |||| .. || .. .|....| | .||..... | . |||.. ..|. .|.| .|||. .
nkdknRltqilvpdnyrvllk....gehpdyinavfidgykekk.afiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpe.....ek
GlgdMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSD-TERIVMHYWFNSWPDHG-VPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
. | |...| ...||| ||..|..... ... |. | . .|...| |.. .. . . ... . . .||||..|||...|. ...
s...vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaat
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
... .. | .| ..... | . .|| || .| .... |
tinkckteGviDvfqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 27-266 | 1.4e-47 | 156.9 | In-house | 39-275 (287) | alignment | ||
Range on Protein: 27-266
Range on HMM: 39-275/287.0
SNLNRYNNILPNPRTRVRLSKLNDdDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfnEREG
. ||| ..|| ||| ||. . . ||||||| .| . ..||.||| ..| ||||.|.||.. |....| |..| || .||| |||
vkknryadvlPiddtrvllsaege.lGsdyinanyvasytd.deafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywP.....erev
lgDMQA-GFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAV-----REWSDDPERPWIVHCSAGVGRTGTFIT
|. |. |.. ... | ||. . .. |.| . . ||||.... . .... | . . . | .||...|.||.|....
..PmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGilla
IDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
. . .. |.. || .| .. |||. | |.|| . | . |. |
tlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvt
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 29-263 | 1.7e-47 | 156.6 | In-house | 6-234 (237) | alignment | ||
Range on Protein: 29-263
Range on HMM: 6-234/237.0
LNRYNNILPNPRTRVRLSKLNDDdiTTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfNEREGLG
||| || .|| | . . ||||.|..|.||. .|||.||| .. |||.|||. . |||.||| |. ..|| .||| .. . |
knrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst..dqpaayg
DMQAGFVNVAVLAGVRSNGYIATKlrikHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD--PERPWIVHCSAGVGRTGTFITIDIGMR
. . .. .. .| . . |.. | | ||||.||| .| .... . . . | |||.|||||||||| |. || .|
vltvslkkkeefsdytvrslllsk....rltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlr
LLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKV
.|. .. . . . .|| ..| .| | ...
qakekkvvdiynyvysieedrpyiiqtkdqyvfihqt
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 24-267 | 2.2e-47 | 156.8 | In-house | 46-287 (325) | alignment | ||
Range on Protein: 24-267
Range on HMM: 46-287/325.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMV--WEtnaNSIVMVTGLQEKGREKCARYWPTVLF
| . ||..|... ..|| | ..|| . ||||.|.. . . ...|.| | ..|. |.||.| |. |.|.|. ..| ..|| ||| .
penkaknrfknvvaldksrvvletkkddpssdyinasylrddkk.kdvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcavywpkemg
NereglgDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD------PERPWIVHCSAGVGRT
. . | ..| . . |. .| .| | | | . . ||.| ||. .. .|| | . |. | .||||||||||
k......sktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrt
GTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|.||.. . . | | .. . ...||||| .||. .| . |. | |.
Gvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 28-266 | 6.1e-47 | 154.9 | In-house | 3-169 (182) | alignment | ||
Range on Protein: 28-266
Range on HMM: 3-169/182.0
NLNRYNNILPNPRTRvrlsklndddITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTglqekgrekCARYWPtvlfneregl
..||| .|||....| .|||||.. |. | .||||||.. |..||.||..| . ..||..| . .|||
dknrysdilpydhsr..........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywp..........
gdmqagfvnvavlagvrsngyiatklrikhdkSDTERIVMHYWFNSWPDHGVPSeTGNVVKMLQAVREwsddPERPWIVHCSAGVGRTGTFITIDIGMRL
.. || ...|.. .|||||||. . .......|.| ...| .||||||||||||.. ... ..|
................................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl
lqergRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
.... |... .|. |. ||..|.| | . .| |
.....gvsleeavklvrsrRpgmvitpnqyfflqlalle
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 27-267 | 2e-46 | 154.5 | In-house | 47-279 (314) | alignment | ||
Range on Protein: 27-267
Range on HMM: 47-279/314.0
SNLNRYNNILPNPrTRVRLSKLNDDDiTTYINANYVHGYdgahGTYIATQGPTPTTTPDF----------WRMV--WETNANSIVM--------------
. ||| .||| . .||.|..|. .. . ||||.||.|. ..||||||.. | || |||| .. | |||
rdknryldilpad.nrvilpglpvsg.sdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLd
-------VTGLQEKGREKCARYWPTVLfnereglgdmqagfvnvavlagvrsngyiatklRIKHDKSDTERIVMHYWFNSWPDHGVPsETGNVVKMLQAV
..| ..| | .|..... .. .|... || ...|. .||...| . . ..|...
aAlgKtpllildgngneptaadlellk.................................eelydpelferlgikylripvpDgsap.lledfdeflefi
REWsdDPERPWIVHCSAGVGRTGTFITIDIGMRLLqergRCNVNEIIRRLRKDRC-----AMVQHPEQAEFAYKVLSEY
.|. |...| .|||.||.||||||..... |.|| .....|.....|. | ... .|| || ...| ||
eea..dkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealley
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 29-267 | 6.5e-45 | 148.0 | In-house | 45-289 (296) | alignment | ||
Range on Protein: 29-267
Range on HMM: 45-289/296.0
LNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGReKCARYWPTVLfneREGLG
||. ...| .|| |.||. .. . |||| || .. . || |..|. | .|||.|.. .....|..| . . .. ||| .| |
knrdvkvvPyDynRvvLekldGeeksdYinavyvdsflk.kkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks...keqyg
DMQAGFVNVAVLAGVRSNGYIATKL-----RIKHDKSDTERIVMHYWFNSWPD-HGVPSETGNVVKMLQAVREWSDDP-----ERPWIVHCSAGVGRTGT
.. |.. .| ... . || ... . .|||... . |. . ||. | ...... || | . | | .|..| |..|.|
eifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGv
FITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
...||. . |... .. .| | ...||..| .|. |. . | ||.|.
ylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 28-264 | 9.7e-45 | 147.6 | In-house | 47-232 (392) | alignment | ||
Range on Protein: 28-264
Range on HMM: 47-232/392.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGrekcarywptvlfneregl
. |||.|||| ..||.| ..| . |.|| |....| . .|||.||| ... ||||||.. |. .|.||| |.|
kknryknilpydsarvkleviddipdsdylnasyipsfdn.ekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...................
gdmqagfvnvavlagvrsngyiatklrikhdKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRL
| | | | . | |||..|| | ...|... |. . .| |.|||||||||| |.|| .
...............................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvah
LQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVL
.. .| ... .|. | ||| || | | .
akktrmvdvfnfvtnirrkrpymvqtkeqyafiygav
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 6-195 | 2.2e-44 | 146.4 | In-house | 8-192 (319) | alignment | ||
Range on Protein: 6-195
Range on HMM: 8-192/319.0
AEEYNAIDMALVSKKRIPPGTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQ
|||.. . . . .|... . .|. |..| | ||| | . ||| . |..|.|| ||| |. |||.| . .. ||||.||| .. || .| |.
aeefrdlPqliaradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdls
EKGREKCARYWPTvlfnEREGLGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFnSWPDHGVPSETGNVVKMLQAVRE
|.| ..||.|.|| . . . | . |.. . . |. . | .|. . . | . |||. |.. .||.| .. || ||.
elGikvcaeylPt....ketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 29-256 | 2.3e-44 | 146.2 | In-house | 59-271 (290) | alignment | ||
Range on Protein: 29-256
Range on HMM: 59-271/290.0
LNRYNNILPNPRTRVRLSKLNDDDittYINANYVHGydgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfnEREGLG
||| .. | .||| |. | | |. ||||.| . ..| |||.. |. |.|||| .... |||. | |.|. ||..|.| |.||
knrykdvvcndktrvilkdGydGd...yvhanyvkG...lkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyyp.....ekeGev
dMQAGFVNVA-VLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDdperPWIVHCSAGVGRTGTFITIDIGMRL
. | . | . . . | | ... .| | .. |. ||||. |. | ....|...|. | | .||||||.||||||..|..|...
.ltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkasG....pvvvhcsaGiGrtGtfvaievglqi
LQERGRCNVNEIIRRLRKDRCAMVQHPEQ
| . .. ...| ||. | . || |
lldGkeldlldlvralrnsrlnsvqvdiq
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 27-267 | 5.7e-44 | 145.0 | In-house | 41-292 (301) | alignment | ||
Range on Protein: 27-267
Range on HMM: 41-292/301.0
SNLNRYNNILPNPRTRVRLSKLND--DDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNER
..|||..|| . . |. |.. .. ..||||.|..|| .. .||.||| | ||||..|. ||||||.|.|. ..|| .|||. .|.
kalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekk.kfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnse.aes
EGLGDMQAGFVNVAV------------LAGVRSNGYIATKLRIKHDKsdTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDP-ERPWIVHCSAG
| | .. .|| .| . . .|||| |...|.|| . . |. . .||..|| | |.. .. | . | .||||..
eefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdt
VGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
|.|.|......||. . | .| ......|. . .|. || . |.|...|
VsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmy
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 29-264 | 3.3e-43 | 142.8 | In-house | 51-275 (439) | alignment | ||
Range on Protein: 29-264
Range on HMM: 51-275/439.0
LNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGRekcarYWPTvlfNEREGLG
|||... . ||| | .. . ||||||..|| |||||||. || ||||.|.| .. |||.| | | . |||. .. |
knrykdvgafdhtrvtlqeipgvphshyinanyikGyyd.dklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywps...daevcyg
DMqagfvNVAVLAGVRSNGYIAT--KLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPER-PWIVHCSAGVGRTGTFITIDIGM
|. | | . |. |. ..|... || |... . .|||. ||... |...|.|. |. | | .|||||||||||| |..|| .
di.....avrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdial
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVL
|. . ... |.. |||.| |||. | | |. .
eqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynav
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 55-262 | 3.9e-43 | 142.5 | In-house | 3-164 (174) | alignment | ||
Range on Protein: 55-262
Range on HMM: 3-164/174.0
TYINANYVHGYDGAHgTYIATQGPTPtttpdFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfnereglgdmqagfvnvavlagvrsngyiatklr
.||||...... .||.|||.. ||.|..| . ...||.. ..|.|..|| .|||.
dyinaspldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................
ikhDKSDTERIVMHYWFNSWPDHGVPSETGnVVKMLQAVREWSDD-PERPWIVHCSAGVGRTGTFITIDIGMRLLQeRGRCNVNEIIRRLRKDRCAMVQH
...| || ...|.. |||||||. . . .....|.|. . |..| .||||||||||||.. ... .|.| . .. ...|.||. |. |||.
...lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqt
PEQAEFAYK
|.| .| |.
psQyrflyy
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 46-266 | 8.1e-43 | 141.5 | In-house | 4-171 (176) | alignment | ||
Range on Protein: 46-266
Range on HMM: 4-171/176.0
SKLNDDDITTYINANYVHGYdgahgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNEREGLgdmqagfvnvavlagvrs
.| .| .|||||.. |. .||||||.| |..||..|..| . . .|..| ..|.|| ||..||| |..|.
rllgldldldyinanlilgs.....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgi..................
ngyiatklrikhdksdterivmHYWFNSWPDHGVPSEtGNVVKMLQAVREWSDDPeRPWIVHCSAGVGRTGTFITIDigmrLLQERGRCNVNEIIRRLRK
.|.. |||||||. . ..|...||. .. .| .||||||.|||||.. .. ||. . .|.|.....|.
......................qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvre
DRC-AMVQHPEQAEFAYKVLSE
|. .||.||| .| |... .
qRplgavqtpeQyrflyefell
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 25-265 | 1.5e-42 | 140.3 | In-house | 55-289 (297) | alignment | ||
Range on Protein: 25-265
Range on HMM: 55-289/297.0
GTSNLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfner
. . ||....|| .||.|.. .... . |||| . | . .||||||| ..| |||.|||| . ||..| |.|.| ..|.||||
knvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpd......
EGLGdmQAGFVNV-AVLAGVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
|| .. .| | . .. |. . .| ... | | . | |||..|||... ..... . | | .||||.|.||||..| ||.
eGse..vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidl
GM-RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLS
. |||. . .. . || .| .|. .| |||.....
vlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltava
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 28-229 | 1.7e-41 | 137.4 | In-house | 49-257 (418) | alignment | ||
Range on Protein: 28-229
Range on HMM: 49-257/418.0
NLNRYNNILPNPRTRVRLSKLNDDDITTYINANYVHGYDgaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNERE--
. ||| |||| .|||.| |..| . . ||||||. | .|.|||| | | |||||||| . |||.. |. | || |||| . |.
sknrytnilpvnhtrvqlkkiqdkegsdyinanyidgay..pkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsi
-GLGDMQAGFVNVAVLAGVRSN--GYIATKLRIKHDksDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVRE------WSDDPERPWIVHCSAGVGRTG
| |. | .| .. .. |. ..|. . | . .| .. |||| .| | . ..|... . | | . | ||||||||||||
ygngnevfgtysvelveviqdpereiitrnirltfe..getrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtg
TFITIDIGMRLLQ
|| | | |. |.
tfctavimmkkld
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 27-259 | 3.7e-41 | 135.9 | In-house | 34-257 (283) | alignment | ||
Range on Protein: 27-259
Range on HMM: 34-257/283.0
SNLNRYNNILPNPRTRVRLSKLNDdditTYINANYVH--GYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfner
. ||...|.| . ||.| .. .|||| .. . ||..|.| | |||.||.. .. .|||.| ||| |.||..|||
krknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPk......
EglGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKS-DTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDI
. | .. | |.. . || .| .| .... | .. .. || .. | . | . .||. . . . .. | .||||.|.|||..||..
r..GsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasa
GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEF
. .. .| .... .|..| .|| .| .
svkdaltesvvdvfavvkimreqrmmavqtldqykl
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 52-261 | 7.2e-41 | 135.1 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 52-261
Range on HMM: 3-154/172.0
DITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLqekgrekcarywptvlfnereglgdmqagfvnvavlagvrsngyiat
. ..||||.|...| . .||||||.. |..|||||..| . . ||..|.|
egsdyinasyldlyyipdr.fiatqgplrntladfwrmlkelgithivnltel...............................................
klriKHDKSDTERIVMHYWFNSWPDHGVPsETGNVVKMLQAVRE-WSDDPERPWIVHCSAGVGRTGTFITIDIGMrllqerGRCNVNEIIRRLRKDRCAM
.|... || ...|.. .||||||| . . ..|. ..| .|. | .||||||||||||.. ... . .... |... .|. |. .
....lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpga
VQHPEQAEFAY
||.|.| | |
vqnpsqyrfly
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 71-262 | 1.9e-38 | 126.9 | In-house | 10-144 (152) | alignment | ||
Range on Protein: 71-262
Range on HMM: 10-144/152.0
TYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWptvlfnereglgdmqagfvnvavlagvrsngyiatklrikhdksdterivmHYW
.||||||.| |..|||||..| ... |||.| |.|.|..||..|. .|
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...................................................qyl
FNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMrllqerGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYK
. |||||||. . . .|...... |.. | .||||||||||||.. ... . .... |.....|. | .|..|.| .| |.
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 24-189 | 6.1e-38 | 125.4 | In-house | 31-189 (297) | alignment | ||
Range on Protein: 24-189
Range on HMM: 31-189/297.0
PGTSNLNRYNNILPNPRTRVRLSKLNDDdiTTYINANYVHGYDGAHG-TYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfN
... |||..|| |||.| . . . ||||.|| | . || .|||. .| |||..|.| . . ||||. ||| ||.||| ||| | .
nsslrknryrdilatddtrvkllrvite..rdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvv.q
EREGLGDMQAGFVNVAVLAgvrSNGYIATKLRIKHDksDTERIVMHYWFNSWPDHGVPSETGNVVKM
|| ||. |. . | |.|.. . . .| | | | |||||||||. ..|..
erlkagdvvveflsstsde...fdrviltelqliyr..sesrvvrhvqflswpdhGvpsdledlvrf
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 27-266 | 1.5e-37 | 123.8 | In-house | 38-267 (281) | alignment | ||
Range on Protein: 27-266
Range on HMM: 38-267/281.0
SNLNRYNNILPNPRTRVRLSK-LNDDDITTYINANYVHGYDGAHGtYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPtvlfneRE
. ||| || .||.| . . . | || |||.. .| || |||| | |||||.|. |. .|||. . | ||||| |.| |.
nkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrg.yiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfp......rn
GLGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKsdTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPerpwIVHCSAGVGRTGTFITIDIGM
.| . |. . ..|.| . .. |.. |. .. ||| || . ..|.|. .| | | ..||||||||.||.....| .
ahcclqfdklsvsyedstvnkslvttrlnlsyeg..etrlithwlwkewpdwqvpessevmlkilrkirarstpp....vihcsagvgrsgtlmaveial
RLLQER-GRCNVNEIIRRLRK-DRCAMVQHPEQAEFAYKVLSE
. .. . ....|. .|| |.| || .| . .||| .
qsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 27-267 | 4.8e-36 | 119.3 | In-house | 42-276 (307) | alignment | ||
Range on Protein: 27-267
Range on HMM: 42-276/307.0
SNLNRYNNILPNPRTRVRLSklNDDDITTYINANYVhGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNErEG
.. |||... ..|. . | . || |||. | .|..||| .| .|| |. . . .|..|. . | .. || .||| . ..
tdknryqdvkcqdkgrivvk..fdglasdyihanyl.giaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqk.lv
LGDMQAgFVNVAVL---AGVRSNGYIaTKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREwsddPERPWIVHCSAGVGRTGTFITIDI
|. ..|| | . .| .| | .. | . |. .. |||.||| . . .|.||| . | .|||||||||.|| ..| .
fgeapn.tisvanlgakklapdedli.nvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry....dtnpvvvhcsaGvGrsGtivaisl
GM-RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. .... ....... ||..| .| | . ..|| ||
vqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 53-264 | 3.3e-35 | 116.2 | In-house | 2-149 (151) | alignment | ||
Range on Protein: 53-264
Range on HMM: 2-149/151.0
ITTYINANYVHGYdgahgtYIATQGPtpttTPDFWRMVWETNANSIVMVTGLQEKGreKCARYWPTVLfnereglgdmqagfvnvavlagvrsngyiatk
...|||..|| |. .....|| ..||.....| . ..||......| | .|..|.|
lsdyinfsyvtgg......lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg................................
lrikhdksdteRIVMHYWFNSWPDHGVPSETGNVVKMLQAVREwsdDPERPWIVHCSAGVGRTGTFITIDIGMrlLQergrCNVNEIIRRLRKDRCAMVQ
. |.|... .|||.|.| . |...|..... ... | .||||||.|||||.. ... . |. ....|... .|. |. .||
...........ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylml..lg....vsleealeeyrlkrpgvvq
HPEQAEFAYKVL
...| | ...|
pnqqflfqlfal
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 28-266 | 1.1e-34 | 114.5 | In-house | 45-274 (312) | alignment | ||
Range on Protein: 28-266
Range on HMM: 45-274/312.0
NLNRYNNILPNPRTRVRLSklndDDITTYINANYVHGYDgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTV-LFNEREG
.|||| || | | |. | || ||.|. ...|||| |. ||... . ||....|. | | ||||.| . | . |
dlnrypniqcwdrgrftla....gdenfyihanfvkict.kperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdled
LGDMQAGFVnvAVLAGVRSNGYIATK-LRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREwsdDpERPWIVHCSAGVGRTGTFITIDIGM
. | .|. |. . |.. . | . || . ||||||.| ..| ||. | .| | |||||||||||.. |. .
hrvyteyct..eieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkk...d.kkpviahcsagvgrtgtlaliesmi
RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
|. . || .. |||||. |. | .| ... |
aalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvle
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 37-264 | 1.1e-34 | 115.0 | In-house | 1-167 (178) | alignment | ||
Range on Protein: 37-264
Range on HMM: 1-167/178.0
PNPRTRVRLSKLNDDDITTYINANYVHGYdgahgTYIATQGPtptttPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFnereglgdmqagfvn
| .|||| ||.| . . ||||... .. |.....| .|......| . ..||..|. .| |..|| .|||.
pldrtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag...............
vavlagvrsngyiatklrikhdksdterivMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRLlqergRCNV
..| . .||||||. . . .......|. |....| .|||||||||.||.. ... ..| ....
..............................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsl
NEIIRRLRKDRCaMVQHPEQAEFAYKVL
.|.|...|. |. .|..|.| .. |..
eeaielvrerRp.ivpnpgqlrqLyefe
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 29-266 | 7.1e-34 | 112.1 | In-house | 50-342 (350) | alignment | ||
Range on Protein: 29-266
Range on HMM: 50-342/350.0
LNRYNNILPNPRTRVRLSKL--------NDDDITTYINANYVHGY----DGAHGT-YIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARY
|||.|||| ..||.| | ||||||.. . . |||||.|.| | ||.... . . . |...| ..| ..||| ||
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrY
WPTVLFNE--------REGLGDMQAGFVNVAVLAGVRS-NGYIATKLRIKHDKSDTE--------RIVMHYWFNSWPDHGVPSETGNVVKMLQ-------
|. ... .| .... .| . . | | |. . .|. .| |. .|.. .. |.| .. . .....|.
WqegsydditvklaskwenimgindsslysadvkkeasdndnisddndlkdnnsltaitlaasdPyvvyqlqvknWkDlslllnPesilqalevkndlid
---AVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMR------LLQERGR---------CNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
| .. | .||||||||||||..|.| . |... | .. |. .||| | ||| .| | |. |
dlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallf
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 27-267 | 1e-33 | 111.6 | In-house | 36-269 (285) | alignment | ||
Range on Protein: 27-267
Range on HMM: 36-269/285.0
SNLNRYNNILPNPRTRVRLSKlNDDDittYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNEREG
.|||| .. ||| | . | | || |.... . |||.|||| | | |||.|... . ..|. | | | |||| |.| | |
pdlnryadvrcieetrvvlkn.hdrd...yihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypekl.gevvk
LGDMQAGFVNV--AVLAGVRSNGYIATKlriKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWsDDPERPWIVHCSAGVGRTGTFITIDIG
.| . . .. .|| | .. | | . | |||. | .. .... . |.. . |.| |||||||||| ||. ||
fgkyeitlteckeeaiagtilnaltvin...tedasseplymnhvqvpwwpdqlapedarpmielykwvkkv.npkekpicvhcsagvgrtatfvgidya
MRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. | .. .|.| .| | || | | | || ||
tirimenpniemldivremramrfqavqshmqflflyvvlmey
|
|||||||||
| PTPc_DSPc_SM00012 | 166-265 | 2.8e-33 | 109.6 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 166-265
Range on HMM: 2-104/105.0
VMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPE--RPWIVHCSAGVGRTGTFITIDIGMRLLQER-GRCNVNEIIRRLRKDRCAMVQHPEQAEFAYK
|.||....|||||||.|. .....|.||... . | | .|||||||||||||...|| .. |... .. .. .|...||| | ||| || | |.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
VLS
.|
all
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 29-267 | 3.3e-33 | 110.0 | In-house | 46-270 (288) | alignment | ||
Range on Protein: 29-267
Range on HMM: 46-270/288.0
LNRYNNILPNPRTRVRLSklndDDITTYINANYVHgYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNEREGLG
.||.|. |||.|| || ||.|| | . | .| | .| .|.|. |.. . |||.. | |||.|| | |.|..| |. .|
rdryenlprcditrvkls....ddpdfyiaanvvs.sakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPskl.Gekarig
DMqAGFVNVAVlAGVrsNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVrewsDDPERPWIVHCSAGVGRTGTFITIDIGMRLL
. | . |.. . . | . . ... || . .. |.|.||| . ...|. . . ..| .||.|||||||||.| | | .. |
rl.ctvvkkkr.adi..dklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl....kslqkPivvhssaGvGrtgtlililialesl
QERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. ..... .||..| .| | ...... |.
rlddflgirsllaklreerfkaiqtemqylyvhrcvlee
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 28-256 | 5.9e-33 | 108.9 | In-house | 52-269 (301) | alignment | ||
Range on Protein: 28-256
Range on HMM: 52-269/301.0
NLNRYNNILPNPRTRVRLsklNDDDITTYINANYVHGYdGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFnEREGL
. .||... .| | |.. .| | ||.. | .|||||| . |. ||| |. . . |||.. || |||. | |. |. .
dkhryptvPckPstavev...ivdGkrvPihanwipts.GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis.ekldi
GDMQAGFVNVAVLagvRSNGYIATKLRIKHDKSD-TERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREwsddPERPWIVHCSAGVGRTGTFITIDIGMR
| . .| .. .. . .|... . . | |.|| ...|.|.||| .. .... |.. |.| .||||||.||. .||. .. |
grfkikiknkeli...lnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkk....sekPivvhcsaGiGrsvafigteylar
LLQERGRCNVNEIIRRLRKDRCAMVQHPEQ
.. . ...| ...||..| ||. .|
eveadptieltealkhlrehrwngvqtnsq
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 28-267 | 1.3e-32 | 107.6 | In-house | 57-288 (305) | alignment | ||
Range on Protein: 28-267
Range on HMM: 57-288/305.0
NLNRYNNILPNPRTRVRLSKlndDDITTYINANYVHGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNEREgl
|||... . .. |.|.| . || |||| . .|..||| | .|| || . . . |||. | |. |||.|||. . .|
tknryqdvpcqdqsavkldk...pspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle..
gdMQAGFV--NVAVLAGV-RSNGYIATKLRIKHDKsDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREwsddPERPWIVHCSAGVGRTGTFITIDIG
...| | ||. . | . | |.. . | . | | .. ||| ||| ...| |.| . | .||||||.||||| ..|.
..lksgivvenvsgskpmerdaeiqitllnltysg.dqkmsvrhlqwtewpdrgvppckltslellsairg....skvpivvhcsagigrtgtivaieyi
MRLLQERGRCN-VNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
. . | .| . |... || .|. .| | | ..|. .|
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 21-267 | 7.7e-31 | 102.1 | In-house | 28-258 (267) | alignment | ||
Range on Protein: 21-267
Range on HMM: 28-258/267.0
RIPPGTSNLNRYNNILPNPRTRVRLSKLNDDdittYINANYVHGYDGaHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTglqEKGREKCARYWPTVL
|. . ||... || ||| |.. ... |||| ||.|| ..|.||.| | ||. .. . . ||..| . .. ..|| .
siaeknqernrlddnlpyddtrvilrtkeee....yinasyvegykt.knafivtqdplkntitdfltvihdqkvpvivllt...kvftdnirlfwPPkm
FNEREglgdMQAGFVNVAVlaGVRSNGYIATKLRIKHDKSDTeRIVMHYWFNSWPdhgVPSETGNVVKMLQAV--REWSDDPERPWIVHCSAGVGRTGTF
. .. | |. .. | | | .| . . . | |... | . .. .| | .. .. .. .|| .|.||.||||.|||
gqakk....yqdltvehsl..ekeendyqiitlelkfknesa.hnvtlyyykkwn...intnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtf
ITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
..|| .. ... | .. . .|..|. | ..|. |. . ...|.||
lvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 29-267 | 2e-30 | 100.6 | In-house | 51-286 (305) | alignment | ||
Range on Protein: 29-267
Range on HMM: 51-286/305.0
LNRYNNILPNPRTRVRLsklNDDDITTYINANYVHGYDGAHgTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVL-----FNE
||| .. . ||.| . || |||| .. .| || | | ||| | .. . ..| |. |.||| .||. |... |.|
knrykdvgcldnnrvkl...egpwpheyihanyvstptnpk.rfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefee
REGlgDMQAGFVNVaVLAGVRSN---GYIATKLRIKHDKSDTeRIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWsddpERPWIVHCSAGVGRTGTFIT
.. .. | | |.. .|.| |. ... | | || .. ||| |||. ....|. | | .||||||.||||. .
kgq..kisvkfess.vtlkfrkdakakvtetvlviegpgeka.rkvthyhwidwpdrgvpaadlailellekarps....kgpivvhcsagigrtgsvvm
IDIGM-RLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
.. . .||. . . . |....|..| .| .| | ..|. .|
leyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilny
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 30-257 | 6.1e-30 | 98.8 | In-house | 56-279 (310) | alignment | ||
Range on Protein: 30-257
Range on HMM: 56-279/310.0
NRYNNILPNPRTRVRLsKLNDDDITTYINANYVHGyDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNEREGLGD
||| ... .||.| |.. || ||||. . |.| .||| | |||||... |.||... |.|| || |||.. | |
nrysdvvcldtsrvkl.kidksryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcir
---MQAGFVNVAvlAGVRSNGYIATKLRIKHDKSDTE--RIVMHYWFNsWPDHGVPSETGNVVK--MLQAVRewsddpERPWIVHCSAGVGRTGTFITID
. . . .. .. . . .. . |. . | | ||| ||| | | .| || | .||||||..|... ....
vtnlsesseefe..icnlavtfvpdnvpvdeqpanlkelrvslikwpn.wpdrgvpdekchtvpqrllaqvr......hgpcvvhcsagkdrlyvvvalk
IGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQA
. . |.. . ...|.. |.|.| .| . |
lkidkldrglkvdaeevktellksraiciqtelqy
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 71-263 | 5.4e-29 | 95.8 | In-house | 6-199 (199) | alignment | ||
Range on Protein: 71-263
Range on HMM: 6-199/199.0
TYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfneREGLGDMQAGFVNVAVLAgvRSNGYIATKLRI--KHDKSDTERIVMH
||||| | | |||.||||| . |||| | . . ||||. | | . . | . ... | | | . . . | . |
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywptt....esgtgkygslsvttktit..tkpdytitaliltnnttappstreish
YWFNSWPDHGVPSET---GNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRLLQERGRCN--VNEIIRRLRKDRCAMVQHPEQAEFAYKV
| | || .. | . | || . . . .. . | ||||| | | || |...|||.| .| . |. .|||. || .. .. .| |.|
yqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 71-263 | 5.4e-29 | 95.8 | In-house | 5-198 (198) | alignment | ||
Range on Protein: 71-263
Range on HMM: 5-198/198.0
TYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVlfneREGLGDMQAGFVNVAVLAgvRSNGYIATKLRI--KHDKSDTERIVMH
||||| | | |||.||||| . |||| | . . ||||. | | . . | . ... | | | . . . | . |
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywptt....esgtgkygslsvttktit..tkpdytitaliltnnttappstreish
YWFNSWPDHGVPSET---GNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRLLQERGRCN--VNEIIRRLRKDRCAMVQHPEQAEFAYKV
| | || .. | . | || . . . .. . | ||||| | | || |...|||.| .| . |. .|||. || .. .. .| |.|
yqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 149-265 | 9.1e-25 | 82.4 | In-house | 30-140 (145) | alignment | ||
Range on Protein: 149-265
Range on HMM: 30-140/145.0
IATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPeRPWIVHCSAGVGRTGTFITIDIGMRllqeRGrCNVNEIIRRLRKDRC
| | |.. ..... || ...|.. .|||||||. . . ..|....|. ... .| .||||||||||||.. ... .. .| ... |.....|. |
ittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrp
AMVQHPEQAEFAYKVLS
.|..|.| .| |...
gavpnpgqlrflyefel
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 153-262 | 5.8e-24 | 79.9 | In-house | 36-139 (144) | alignment | ||
Range on Protein: 153-262
Range on HMM: 36-139/144.0
LRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDdPERPWIVHCSAGVGRTGTFITIDigmrLLQERGrCNVNEIIRRLRKDRCAMVQ
|. .... . || ...|.. .|||||||. . . ..|....|. . ...| .||||||||||||..... |. ..| ....|.....|. |. .|.
lteeyepefleregiqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavp
HPEQAEFAYK
.|.| .| ..
npgqlrfLle
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 40-264 | 2e-22 | 74.3 | In-house | 54-266 (307) | alignment | ||
Range on Protein: 40-264
Range on HMM: 54-266/307.0
RTRVRLSKLNDDDITTYINANYVHGYdGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKgrEKCARYWPTVLFNEREG-LGDMQAGFVNVA
.||.| . . .| ||.|.| ..| .| | | ||||||.. . . |||.| .| |.| ||| . | .. ..|
ssrvklelrrGqylddfihanrvkGk.pllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvd
VLAgvrSNGYIATKLRIkHDKSDTERIVMHyWFNSWpdhGVPSETGNVVKMLQAVREWSddpeRPWIVHCSAGVGRTGTFITIDIGMRLLQeRG---RCN
| . |||.. | || . | | . |. ...|. .|. | .| .|.. || ...|...|.| . | || .
ska...dplfrvtklkl.vGgddeerfleh.wqgdv...nnssdvysplrvlrklrnls....kpvvvqdilGvskaatlvaieiallsll.rGpitksl
VNEIIRRLRKDRCAMVQHPEQAEFAYKVL
| . . ||. | |. . . | |...
vlravvflrlrrrlsvesvllylfvyrlv
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 40-261 | 3.4e-22 | 73.9 | In-house | 32-252 (290) | alignment | ||
Range on Protein: 40-261
Range on HMM: 32-252/290.0
RTRVRLSKLNDDDITTYINANYVHGYDGAhgTYIATQGPTPTT-------TPDFWRMVWETNANSIVMVTGLQEKGRE----KCARYWPTVLfnereGlG
||| | || ||.| .| |.|| | . .|| |. . .....||. .|| .. ||.| |. | .
atrvvLkgygkrfnddyiHAnrvtcpngl..rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesv.....g.e
DMQAGFVNVAVLAGVRSNGYIATKLRIKHDKSdTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVRewsdDPERPWIVHCSAGVGRTGTFITIDIGMRLL
... . ..| . .. . .| .|.|. | | |.....| . |. .| .....| |. . | |||| |. | .. .|..|. ..
elkfkgltvkCkskekeddvetRelvvkfdde.eeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQki
Q-ERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAY
.| ...... ||| | ....... |.
aetsgsvkledvlkalrkqralaitsalelafvd
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 77-257 | 1.9e-20 | 67.5 | In-house | 98-277 (302) | alignment | ||
Range on Protein: 77-257
Range on HMM: 98-277/302.0
GPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLFNE-REGLGDMQAGFVNVAVLAGVRSNGYIATKLRIKHDKS--DTERIVMHYWFNS
| |. .| .. . | .| .... |.. .||| |. . . .| . | ... |. . ... .. || .| .... | | .
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDHGVPSETGNVVKMLQAVREWsddpERPWIVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQA
||||| | |. . ...|. . . .||||||||||||...| |. | ... ... .|. .|. | ||. .|
wpdhGapkeaytaldilkfcesy....kknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqql
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 82-262 | 3.1e-20 | 67.3 | In-house | 40-215 (255) | alignment | ||
Range on Protein: 82-262
Range on HMM: 40-215/255.0
TTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNEREGLGDMQAGFVNvavlagvRSNGYIATKLRIKHDKS--DTERIVMHYWFNSWPDHGV
| |.... |... .||.. ..|.|.||| .|.|. . .|. | |.. . |. . |.| . . | || .. |...
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplek.deklkladvnvtttk.......ssadvvlrtleitstlgekkkthtvkhysykGWiekna
PSETGNVVKMLQAVREwSddpeRPWIVHCSAGVGRTGTFITIDIGMR----LLQE--RGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYK
| .. .. ..|..||. | .. .||||.|.||. .|. ... . |.. . . .... ||. | . .. | | |.
Pelareilnilkvvrd.s....ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsil
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 139-264 | 5.1e-20 | 66.2 | In-house | 68-190 (440) | alignment | ||
Range on Protein: 139-264
Range on HMM: 68-190/440.0
VLAGVRSNGYIATKLrIKHDKSdteRIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDD-PERPWIVHCSAGVGRTGTFITIDIGMRLLQERGRCNVN
. || .. || . |. .| | . .| ...|||.||| .| |.||.| | | . . | .||||||.|||| |..| .| . . ..
evkgvpdsdyinasy.ingies...rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidif
EIIRRLRKDRCAMVQHPEQAEFAYKVL
.| .|..| ||| ||| | ....
sfinsmrnnrpqmvqtpeqyafvheav
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 82-262 | 2e-17 | 57.9 | In-house | 46-221 (263) | alignment | ||
Range on Protein: 82-262
Range on HMM: 46-221/263.0
TTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTVLfNEREGLGDMQAGFVNVAVLAGVRSNgYIATKLriKHdKSDTERiVMHYWFNSWPDHGVPS
| . |.... |... .||.. .|.|.||| .|.|. . .|. | ... .| .... . | .. | |. | || .. |... |
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlek.dekqklanvnvcttkvqsdvllktl.ellstl..ge.Kkktht.vkhysykgWiekndpe
ETGNVVKMLQAVREWsddpeRPWIVHCSAGVGRTGTFITIDIGMR----LLQE--RGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYK
.. .....|...|. .. .||||.|.||. | ... . |.. . . .... ||. | . .. | | |.
lareilnilkvarns.....kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsil
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 56-265 | 1.8e-16 | 54.5 | In-house | 77-282 (302) | alignment | ||
Range on Protein: 56-265
Range on HMM: 77-282/302.0
YINANYVHGYDGAhGTYIATQGPTPTTT---PDFWRMVWETNANSIVMVTGLQEKGReKCARYWPTvlfnEREGLGDMQAGFVNVAVLAGVRSNGyIATK
|.|| |. . . | .| |. ... .|||||.. . |.|.. | .| . ..|. . . .... |||. . . .
yvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpk....ksgdykeygkmfvNnrkVekaeeek.tryv
LRI-KHDKSDTeRIVMHYWFNSWPDHGVPSETGNVVKMLQAVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMV
. . .. |.. ... | .. |... || . ....| . | . . . . . .. |.|| |.|.| . . ||. |..||.. .|..|...|
iEvlPegcsns.vlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRprav
QHPEQAEFAYKVLS
. .| . | .|
dslkQyvslyiall
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 202-267 | 5.6e-16 | 53.1 | In-house | 248-314 (319) | alignment | ||
Range on Protein: 202-267
Range on HMM: 248-314/319.0
RPWIVHCSAGVGRTGTFITIDIGMRLLQER-GRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
| .|||| ||||||. |. || .| |.| .. ... .|.||. |. || || |||||||
GPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 29-266 | 3.1e-14 | 47.3 | In-house | 50-277 (303) | alignment | ||
Range on Protein: 29-266
Range on HMM: 50-277/303.0
LNRYNNILPNPRTRVRLSklnDddiTTYINANYVHgYDgAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEkgrekCARYWPTVLFNEREGLG
||. ... ..|.|| | ..|| |.|.. | .. | || | . |. |||.|. | . . .... | .. ..| . . .
knrfvdvicldhskvkls...d...ssyihasyle.ld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdse.....ydklggdsvfprnqdfl
DMQAGFVNVAVLAGVR-SNGYIATKLRIKHDKSDTERIVMHYwfNSWPDHGVPSE-TGNVVKMLQA----VREWSDdpERPWIVHCSAGVGRTGTFITID
... .. | . | ..|. | . . . | || ..|| .||. . ..|| . .| .|| .| . .|.||.||| ..
kfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhy..kawphnsipsdgspkfvkqiwqlqsvlrkysd..stptvymslsgcgragtfalfe
I-GMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSE
. | .|. .. . .|. | || | . | .|.|
tahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllae
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 157-264 | 3.1e-13 | 45.3 | In-house | 70-173 (194) | alignment | ||
Range on Protein: 157-264
Range on HMM: 70-173/194.0
HDKSDTERIVMHYWFNSWPDHGVPSETGNVVKMLQAVREW-SDDPERPWIVHCSAGVGRTGTFITidigmRLLQERGRCNVNEIIRRLRKDRCAMVQHPE
|... |. ..| .||.|.. . .. . |..| |. ..||. ||| ||.|||||.. . | .| .....| |...| | ......
YdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva.....aYLiyrlgmsaeeAialfrekRpgaipnqd
QAEFAYKVL
. | .|
yleallkry
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 30-146 | 2e-12 | 41.1 | In-house | 52-181 (349) | alignment | ||
Range on Protein: 30-146
Range on HMM: 52-181/349.0
NRYNNILPNPRTRVRLSKLND--------------DDITTYINANYVHGYD-GAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCAR
|||..||| .||.| | . ||||||.. .. ||||| | |.| ||.... . . .. .. .|.. ||| .
nrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdi
YWPTVLFNEREglGDMQAGFVNVAVLAGVRSN
|| ... . .| . ..| . | ..
ywqelsysnit..vklqnsslyianvqGnslr
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 17-118 | 8e-12 | 39.3 | In-house | 87-180 (244) | alignment | ||
Range on Protein: 17-118
Range on HMM: 87-180/244.0
VSKKRIPPGTSNLNRYNNILPNPRTRVRLSKLNDDdiTTYINANYVhGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKgrekcARYW
| | . | | || || || ||| . ||||| .| | | || || | |. |||.|. | | .|.. ..|. ||
vmkdafnpnnswknregaglpfdfnrvplskgsmg..ntyinasfv.gclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deyw
PT
|
pd
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 29-181 | 1.9e-11 | 37.9 | In-house | 53-196 (332) | alignment | ||
Range on Protein: 29-181
Range on HMM: 53-196/332.0
LNR-YNNILPNPRTRVRLSKLNDDdITTYINANYVhGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKGREKCARYWPTvlfNEREgl
.|| .|.|. | |||. . |||| . . || | . . . ||.|| | .. .||.. |.. || .|.| . ||
vnrnvvkivpydrylvrltssqln.rlGyinasla.efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpd...ktre..
gDMQAGFVNVAVLAGVRSNGYIATKLRIKHdKSDTERiVMHYWFNSWPDHGVPS
.. |...| |. | . .| .. .| | |.|| . | . .|
.elkfGildverkefvkrniletrllelsk.Gnethr.vlhykvfGwtettlpk
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 203-263 | 4.2e-10 | 34.0 | In-house | 230-290 (297) | alignment | ||
Range on Protein: 203-263
Range on HMM: 230-290/297.0
PWIVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKV
. .|||||||||.| . |. . |. . .|. |.. ||. | .|| || |. |..
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 41-101 | 7.5e-10 | 32.8 | In-house | 52-116 (347) | alignment | ||
Range on Protein: 41-101
Range on HMM: 52-116/347.0
TRVRLSK-----LNDDDITTYINANYVHgYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMV
||| || . ||. ||||| ... .| |. || || | | | |||.|| |. .| .
trvvlspeksknsraddvetyinashik.fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
| PTEN_1 | 173-260 | 9e-10 | 33.7 | In-house | 101-185 (196) | alignment | |||
Range on Protein: 173-260
Range on HMM: 101-185/196.0
SWPDHGVPSETgNVVKMLQAVREW-SDDP-ERPWIVHCSAGVGRTGTFItidigMRLLQERGRCNVNEIIRRLRKDR-CAMVQHPEQAEFA
...|||.|| . ... . || . || .. .||| ||.||.|| . . .| ..|. ...| ....|. | ..... |.| ..
pieDhgapsls.elfdicksfiewllsdpngnvVlVHCkaGlgRsGtvv.....aayLmykgkltadeAlelvrekRppgapnspsqerll
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 192-265 | 5e-09 | 29.9 | In-house | 256-341 (349) | alignment | ||
Range on Protein: 192-265
Range on HMM: 256-341/349.0
AVREWSDDPERPWIVHCSAGVGRTGTFITIDIGMRLLQERG----R--------CNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLS
| . .| . .|||||| ||||...|.|. . .|. . . |. ||| | .||| | . |. |
arlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealL
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 205-264 | 1.4e-08 | 29.0 | In-house | 1-60 (69) | alignment | ||
Range on Protein: 205-264
Range on HMM: 1-60/69.0
IVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPEQAEFAYKVL
.||||.| |||||||.| . | .. .. . .. .|| | || .. | . |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdal
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 205-255 | 2.2e-08 | 28.4 | In-house | 2-52 (69) | alignment | ||
Range on Protein: 205-255
Range on HMM: 2-52/69.0
IVHCSAGVGRTGTFITIDIGMRLLQERGRCNVNEIIRRLRKDRCAMVQHPE
.||||.| |||||||.| . | .. .. . .. .|| | ||
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmnei
|
|||||||||
| subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 30-188 | 2.5e-08 | 27.0 | In-house | 31-163 (169) | alignment | ||
Range on Protein: 30-188
Range on HMM: 31-163/169.0
NRYNNILPNPRTRVRLSKLNDDDITTYINAnyvhgydgahgtyiatqgptptttpdfwRMVWETNANSIVMVTGLQEKGR---EK-CARYWPTVLFNERE
|| | .|||.| .. .| . |||| ||.||||| ||.. . ..| || . |.|.. |
nrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlgdtddknnfwpekedyqlhpavilgewy
GlGDMQAGFVNVAVL-AGVrsNGYIATKLRIK-HDKSDTERIVMhYWFNSWPDHGVPSETGNVVK
. | .. .|| .| . . |. .|.. ||.. . . ...||. ||| .| .
t.dslyvrtdkvhantsgv..eglfevsmvihsydddvteklsl.lhystwpqngvpqspvhvgh
|
|||||||||
| subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 30-186 | 8.3e-08 | 25.2 | In-house | 30-160 (169) | alignment | ||
Range on Protein: 30-186
Range on HMM: 30-160/169.0
NRYNNILPNPRTRVRLSKLNDDDITTYINAnyvhgydgahgtyiatqgptptttpdfwRMVWETNANSIVMVTGLQEKGR---EKC-ARYWPTVLFNERE
|| | .|||.| .. .| . |||| ||.||||| ||.. . ..| || . |.|.. |
nrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlGdtddknnfwpekedyqlhpavilGewy
GlgDmqAGFVNVAVLA--GVRSNGYIATKLRIKHDKSDTERIVMHYWFNSWPDHGVPSETGNV
| . .| . .| . | |.. ..| . . . ...||. ||| .|
t..d..slyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqspvhv
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 165-259 | 1.6e-07 | 25.9 | In-house | 82-167 (182) | alignment | ||
Range on Protein: 165-259
Range on HMM: 82-167/182.0
IVMHYWFnSWPDHGVPSETgNVVKMLQAVREWSDDPerPWIVHCSAGVGRTGTFITIdigmRLLQeRGRCNVNEIIRRLRKDRCAMVQHPEQAEF
...| | .|.|.||.| . ... . . | .. ||| || |||| |. |. | . .. |. .|. | .| || |.
giyvynf.gwkDygvasle.riLdivkvvafalqeg..kvavhChaGlGrtGvliac....ylvy.akrltaekaiklvrskrpksiqtreqvel
|
|||||||||
| subfamily_PTEN_pd | Subfamily PTEN | 156-258 | 2.7e-07 | 25.8 | In-house | 72-170 (184) | alignment | ||
Range on Protein: 156-258
Range on HMM: 72-170/184.0
KHDKSDTERIVMHYWFNswpDHGVPsETGNVVKMLQAVREW-SDDPERPWIVHCSAGVGRTGTFITIDIGMRLLQERgRCNVNEIIRRLRKDRCAMVQHP
|.|... . |..| |. || | . . .... ...| . |... .||| || ||||. |. . .|| |. .. |. . | |. |
kydskkfdgrvavypfd...Dhnpp.plelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllkslllek.aeealelfaeaRtknkkgvtiP
EQAE
|
sqrR
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 70-118 | 3e-07 | 24.1 | In-house | 236-281 (440) | alignment | ||
Range on Protein: 70-118
Range on HMM: 236-281/440.0
GTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKgreKCARYWPT
..|||| | .| ||||.| . . .|.|. |..| |. |||
nafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpv
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 54-118 | 4e-07 | 24.4 | In-house | 13-71 (130) | alignment | ||
Range on Protein: 54-118
Range on HMM: 13-71/130.0
TTYINANYVhGYDGAHGTYIATQGPTPTTTPDFWRMVWETNANSIVMVTGLQEKgrekcARYWPT
|||||..| | | |. || | |. |||.|. | | .|.. ..|. |||
ntyinasfv.Gllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpd
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 26-77 | 1.2e-06 | 22.6 | In-house | 46-95 (95) | alignment | ||
Range on Protein: 26-77
Range on HMM: 46-95/95.0
TSN--LNRYNNILPNPRTRVRLSKLNDDDittYINANYVHGYDgAHGTYIATQG
.| ||. ||.| ||| |. | | |||| .| || . |||.||
eanipknrflnifpydatrvvlttkrdsd...yinacfvdgya.rkncyiaaqg
|
|||||||||
| subfamily_VSP_pd | Subfamily VSP | 176-220 | 2.2e-06 | 21.8 | In-house | 103-147 (212) | alignment | ||
Range on Protein: 176-220
Range on HMM: 103-147/212.0
DHGVPSeTGNVVKMLQAVREWS-DDPERPWIVHCSAGVGRTGTFIT
|| ||. ..... . |.|| .|... ..|| | ||||| .
dhnvpk.leellvftkevkewlekdlknvlaihckGGkgrtGtivc
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 29-112 | 3.2e-06 | 20.9 | In-house | 37-118 (332) | alignment | ||
Range on Protein: 29-112
Range on HMM: 37-118/332.0
LNRYNNILPNPRTRVRLSKlnDDDITTYINANYVHGYDgAHGTYIATQGPTPTTT-PDFWRMVWETNANSIVMVTGLQEKGREKC
.|| . ..|| |. .| . ||..| || . .|| .| | | ||||| | . . |... ..|| . |.
mnriphlycfdhsrvelap..qdgkddfynaswvdgys.kksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
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| subfamily_eak_pd | Subfamily eak | 200-267 | 3.5e-06 | 20.6 | In-house | 235-304 (332) | alignment | ||
Range on Protein: 200-267
Range on HMM: 235-304/332.0
PERPWIVHCSAGVGRTGTFITIDIGMRLLQERGR--CNVNEIIRRLRKDRCAMVQHPEQAEFAYKVLSEY
| |. .. | |.|.|. ||. .||.... . |...| . .. | | | | |... .|
psfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy
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| subfamily_CDC14_pd | Subfamily CDC14 | 198-257 | 6.8e-06 | 20.1 | In-house | 260-314 (328) | alignment | ||
Range on Protein: 198-257
Range on HMM: 260-314/328.0
DDPERPWIVHCSAGVGRTGTFITIdigmRLLQeRGRCNVNEIIRRLRKDRCAMVQHPEQA
.. | .||| ||.|||||.|. |.. . | . .|.| || | .| | |
ekaeGaiavhCkaGLGrtGtLiac....ylmk.hyrftaaeaiawlricrPGsvigpqqk
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| subfamily_DSP23_pd | Subfamily DSP23 | 179-259 | 9.3e-06 | 20.4 | In-house | 63-137 (148) | alignment | ||
Range on Protein: 179-259
Range on HMM: 63-137/148.0
VPSETGNVVKMLQAVREWSDDPErPWIVHCSAGVGRTGTFITIdigmRLLQERGRCnVNEIIRRLRKDRCAMVQHPEQAEF
| .||.... | | . | ||| | |||||... |..||. . | | .|. | |. || .
hppaleqvvefvrvveeaeekne.avsvhcllgrgrtgtmlac....ylvkerkla.aaeaiaevrrlrpgsvetveqekl
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