Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0050432 | (Phosphotyrosine protein) phosphatases II | 878-1155 | 1.6e-76 | 252.9 | In-house | 25-296 (308) | alignment | ||
Range on Protein: 878-1155
Range on HMM: 25-296/308.0
EADYQHVTAEVMHLAHASRLEEVYMRLRQEDEdlgYARQTVKAARANPAKNRYSDILPYDASRVPLkqigAAEGDYINANYMPNI---GHRPYIAAQGPL
. .... .... ..||| ...|.. . . .| . .| ||||.|||||| ||| | . |||||.|.. | .||.||||
klsvldllkllekaldlglleeefeellsvkp...lleysvallpenkdkNrykdilpydhsRVkl....degsdYInAsyvdgyssklprkfIatqgPl
PHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQDPG-ASKTFENFTVTCQSLVDAQVYERRRLMVVPRSnvrgvKYEPLVTEHIWMKSWPDHGT
|.| .||||||. .......||... || .|.| ..| |.....||||. | . | .| |.... . . | .. |.....|||||.
pntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlg.....dgesrtvthfhytnWpdhgv
PE-VESFLRCMQAVRRDFeePSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
|. .|..|. ...||. . |.| .||||||||||.||||| |.| . . .. .|| .| .||..| |||| .||.|.|.||
Ppspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyrall
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 887-1155 | 2.6e-75 | 248.9 | In-house | 15-283 (288) | alignment | ||
Range on Protein: 887-1155
Range on HMM: 15-283/288.0
EVMHLAHASRLEEVYMRLRQEDEDlgyARQTVKAARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPN-IGHRPYIAAQGPLPHTEDDFWRM
. ... . ..|.| . .|.. .| ... . .| ||||||||||| ||| |. .. ..|||||.|.. | .||.|||||.| .|||||
lkllangltglleefeellsllpd...ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrm
VYGEHSPLVIMLCSINP---RKCSPYFPQdpGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRgVKYEPLVTEHIWMKSWPDHGTPE-VESFLRCM
|. .......||... .|| .|.|. | |.|....|||. | . . | | |.|.. . .. . |.. |.....|||||.|. .|..|. .
vweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlld.gdgesrtvthfhytnwpdhgvpdspellldfl
QAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
..||. .. ..| |||||||||||.||||| |.| . . .. .|| .| .||..| |||| .||.|.||||
rlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyeall
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 901-1155 | 3e-74 | 245.3 | In-house | 6-271 (284) | alignment | ||
Range on Protein: 901-1155
Range on HMM: 6-271/284.0
YMRLRQEDEDlGYARQTVKAARANPAKNRYSDILPYDASRVPLKQIGA--AEGDYINANYMPN------IGHRPYIAAQGPLPHTEDDFWRMVYGEHSPL
...|.. . . .| .. .| ||||.|||||| ||| || .. ..|||||.|.. . .. .||.|||||.| .||||||. .....
feellsltvk.lllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrv
VIMLCSINPR---KCSPYFPQDpGASKTFENFTVTCQSLVDAQVYERRRLMVVPRsnvrGVKYEPLVTEHIWMKSWPDHGTPE-VESFLRCMQAVRRDFE
..||... . ||..|.|.. | ..|...||||. | . | .|.|.... |.. |.. |....||||||.|. .|..|. ...||. .|
IVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnl....gytgesrtvthfhytswpdhgvppspedlleflrlvrelle
--EPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGH---SMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
...| .||||||||||.||||| |.| . . .. .|| .| .||..| |||| .||.|.||||
nlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyeall
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 911-1155 | 6.1e-73 | 241.0 | In-house | 26-274 (297) | alignment | ||
Range on Protein: 911-1155
Range on HMM: 26-274/297.0
LGYARQTVKAARANPAKNRYSDILPYDASRVPLkqiGAAEGDYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSP
| . .| . .| ||||.|||||| .|| | . . |||||.|.. . | .||.|||||.| .||||||. .... ..||.. . || .
lllgslsvallpenleknRykdilpydhtRVkl...ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq
YFPQDPGASKTFENFTVTCQSLVD--AQVYERRRLMVVPRSNVrgvkyEPLVTEHIWMKSWPDHGTPE-VESFLRCMQAVRRDFEE--PSGRVVVHCSAG
|.| . | |.|...||||..| . | .| | |.. | |... |.....|||||.|| ..|.|. ...||. .. ..|.|.||||||
ywpleegesltygdftvtllsvevvllddytlrtlevtdtgng.....esrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaG
VGRSGTFIAFDMLADAIA---DGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
||||||||| |.. . . . .|. .|..||..| .||| .||.|.||||
vgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeall
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 894-1156 | 1e-72 | 240.4 | In-house | 17-274 (317) | alignment | ||
Range on Protein: 894-1156
Range on HMM: 17-274/317.0
ASRLEEVYMRLRQEDEDlgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSP
. .|.| ...|.. . | .| . .|. ||||.||||||.||| |. .| . |||||.|.. | .||.|||||.| .||||||. ...
ftalleefedllslkld....tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvt
LVIMLCSINPR---KCSPYFPQdpGASKTFENFTVTCQSLVDAQVYERRRLMVVPRsnvrgVKYEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDF
...||.. .. || .|.|. | ..|...||||..| . . .. |.|.|.. . |.. |.....|||||.| ...|. ..|||. .
vivmLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedl.....gdsesrtvthfhytgWpdhgvppspdllldfleavreal
EEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
|.|.| |.|||||||||.||||| ... . . .. .||. .| .||..|. .||| .||.|.|.|| .
edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalle
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 893-1155 | 1.2e-71 | 236.7 | In-house | 10-269 (273) | alignment | ||
Range on Protein: 893-1155
Range on HMM: 10-269/273.0
HASRLEEVYMRLRQEDEdlgYARQTVKAARANPAKNRYSDILPYDASRVPLkqiGAAEGDYINANYMPN-IGHRPYIAAQGPLPHTEDDFWRMVYGEHSP
. ..|.| . .|.. . . .| . .| ||||.|||||| ||| | | . |||||.|.. | .||.|||||.| .||||||. ....
gltllleefelllslkp...lltysvallpenkdknrykdilpydhsrvkl...gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvr
LVIMLCSINPR---KCSPYFPQDPGA-SKTFENFTVTCQSLVDAQVYERRRLMVVPRSnvrgvKYEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRD
...||... . || .|.|.. | |.|...||||. | . | | |.... . |... |.....|||||.| .||.|.....||.
viVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlg.....tgesrtvthfhytgwpdhgvppslesllefielvrka
FEE--PSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
.|. .| |||||||||||.||||| |.| | . .. .||. .| .||..| |||| .||.|.||||
lealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyeall
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 888-1155 | 1.5e-71 | 237.0 | In-house | 20-301 (307) | alignment | ||
Range on Protein: 888-1155
Range on HMM: 20-301/307.0
VMHLAHASRLEEVYMRLRQEDEDLgYARQTVKAARANPAKNRYSDILPYDASRVPLKQIGA--AEGDYINANYMPNI---------GHRPYIAAQGPLPH
...| . ..|.. . .|... .| . .. . .| ||||.|||||| .|| |. .. ..|||||.|. | .||.|||||.
lllldfltgllkefekllsvtvfl.lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe
TEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQDpGASKTFENFTVTCQSLVDAQVYERRRLMVVPRsnvrGVKYEPLVTEHIWMKSWPDHGTPE-
| .|||||.. ... ...||.. .|| .|.|.. | ..|..|||||. | . | .|.| | . . . |.. |.....|||||.|.
tvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtdl....dgtgesrtvthfhytgwpdhgvpps
VESFLRCMQAVRRDFEE--PSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHS---MDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
.|..|. ...||. .|| ..|.|.|||||||||.||||| ... . . ... .|.. .| .||..| .||. .||.|.||||.
feelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeall
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 880-1154 | 3.2e-71 | 235.5 | In-house | 17-285 (297) | alignment | ||
Range on Protein: 880-1154
Range on HMM: 17-285/297.0
DYQHVTAEVMHLAHASRLEEVYMRLRQEDEDlgyarQTVKAARANPAKNRYSDILPYDASRVPLKQIGA--AEGDYINANYMPNIG--HRPYIAAQGPLP
..... .... ..|.. ...| . .| ... . .| ||||.|||||| ||| || .. . |||||.|.. | .||.|||||
svldlllllekansktllllefeellslkpd.....ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlp
HTEDDFWRMVYGEHSPLVIMLCSINPR--KCSPYFPQDPGaskTFENFTVTCQSLVDAQVYERRRLMVVPrsnvrgvKYEPLVTEHIWMKSWPDHGTPE-
.| .||||||. .... ..||.. ... || .|.|.. | |...||||. . . | .| | |.. . |.. |.. .|||||.|.
etvedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg...tygdftvtllkvehldgytvrtlevtn.......ngesrtvthfqytgwpdhgvpps
VESFLRCMQAVRRDFEE--PSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.|..|. ...||. ..| ..|.|.|||||||||.||||| ... . . .. .||. .| .||..|. .||| |||.|.|.||
lellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydal
|
|||||||||
DSPc_SM00195 | 900-1155 | 2.3e-70 | 232.3 | In-house | 5-259 (263) | alignment | |||
Range on Protein: 900-1155
Range on HMM: 5-259/263.0
VYMRLRQEDEDLgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLC
. .|...... . | .. .| .||||..||||| .|| ||.. . |||||||. . |||.|||||.| .||||||. |......||.
efekleestspk...etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
SINP---RKCSPYFPQDPGASKTFENFTVTCQSLVDAQ-VYERRRLMVVPRSNvrgvkYEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDFEEPSG
. . .||. |.|.. | ..||....|.... . ...| | . . |. ......|.|||||.| . .|.|. ..||. . .. ||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.....eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssg
RVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
.||||||||||.|||.. |.. . ..... .|....| .|||.| |||| ||.|||||.
pivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
PTPc_SM00194 | 900-1155 | 2.3e-70 | 232.3 | In-house | 5-259 (263) | alignment | |||
Range on Protein: 900-1155
Range on HMM: 5-259/263.0
VYMRLRQEDEDLgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLC
. .|...... . | .. .| .||||..||||| .|| ||.. . |||||||. . |||.|||||.| .||||||. |......||.
efekleestspk...etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
SINP---RKCSPYFPQDPGASKTFENFTVTCQSLVDAQ-VYERRRLMVVPRSNvrgvkYEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDFEEPSG
. . .||. |.|.. | ..||....|.... . ...| | . . |. ......|.|||||.| . .|.|. ..||. . .. ||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.....eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssg
RVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
.||||||||||.|||.. |.. . ..... .|....| .|||.| |||| ||.|||||.
pivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 895-1154 | 5.6e-69 | 228.0 | In-house | 20-273 (278) | alignment | ||
Range on Protein: 895-1154
Range on HMM: 20-273/278.0
SRLEEVYMRLRQEDEdlgyARQTVKAARANPAKNRYSDILPYDASRVPLKQIGAAE-GDYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSPL
..|.. . .|.. . ... . .| ||||.|||||| ||| |. .| . |||||.|.. | .||.|||||.|..||||||. ....
tllllefeellsfkl....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtt
VIMLCSINPR---KCSPYFPqdpGASKTFENFTVTCQSLVDAQVYERRRLMVVPrsnvrGVKYEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDFE
..||.. . || .|.| | |.|...||||... . | .| | |.. . |.. |.. ..|||||.| ....|. ..|||. .|
ivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtn.....lgdgesrtvthyhylgwpdhgvpeslsllldflkavreale
EPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
..| |.|||||||||.||||| ..| . . ... .|.. .| .||..| .||| |||.|.||||
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 887-1156 | 2.1e-68 | 226.4 | In-house | 15-279 (564) | alignment | ||
Range on Protein: 887-1156
Range on HMM: 15-279/564.0
EVMHLAHASRLEEVYMRLRQEdEDlgyARQTVKAARANPAKNRYSDILPYDASRVPLKQIGAA-EGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRM
. .. . ..|| | ..... . . .. .. || |||||..|..||.||| |... . . |||||... .. |||.||||..| .|||||
aklkansdlkfeeeykkieeg.qq...ftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRm
VYGEHSPLVIMLCSIN---PRKCSPYFPQDpGaSKTFENFTVTCQSLVDAQVYERRRLMVvPRSNVRGVkyepLVTEHIWMKSWPDHGTPEV-ESFLRCM
|. ..| ..|| ... ||. |.|.. | ..|....||| .. .. . || | . . ... . . .. |||||| || .|.|. .
vweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfkl.kkkksses....reVrqFhFtsWPdhgvpesatslLdli
QAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. ||. |. .| .||||||||||.||||. |.. . | . . .|. .| .|||.| .|||| .||.||.||. .
rkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheaile
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 917-1154 | 2.7e-68 | 225.7 | In-house | 26-268 (278) | alignment | ||
Range on Protein: 917-1154
Range on HMM: 26-268/278.0
TVKAARANPAKNRYSDILPYDASRVPlkqigaaegDYINANYMPNIgHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPR---KCSPYFPQdpG
|. . | .||||.|||||| ||| |||||.|.. .. .||.|||||.| .|||||.. .... ..||.. .. || .|.| |
tpalylgnldknRykdilpydhsrVk.........dYINAsyidgy.pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe..g
ASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRgVKYEPLVTEHIWMKSWPDHGTPEVE---SFLRCMQAVRRDFEE-------------PSGRVVVH
|.|...||||..| . | |.|.|. .. | .|.. .|.....|||||.|. . |||.... .|. .. ..|.|.||
gsltygdftvtllseevlddytlrtllvtnltver.edlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVH
CSAGVGRSGTFIAFDMLADAIadGHSMDVDAVVLQLRKHRRI-MVQTASQYQFIYEAL
|||||||.||..| ... . . .. .|.. .| .||..|.. .||. .||.|.||.|
CsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefl
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 924-1154 | 8.7e-68 | 223.6 | Pfam-A | 1-233 (235) | alignment | ||
Range on Protein: 924-1154
Range on HMM: 1-233/235.0
NPAKNRYSDILPYDASRVPLKQIGAAEGdYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQDPGASKTFE
| ||||.|||||| .|| ||. . .. ||||||. . .. .||.||||..| .||||||. |.. ...||.| . .||..|.|.. . |.|..
nkkknRykdilpydktrvklkgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltyg
NFTVTCQ-SLV-DAQVYERRRLMVVPRSNVRgvkyEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLAD
...|... . | . | | | . . . . |. ........|||||.| ...|.|.....|... |. || |||||||||||.|||.| |.| .
dikvelkekekedekeytlrklelkkkkees....ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldille
AIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
. .....|| .| .|||.|. |||...||.|.|.|.
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 924-1154 | 8.7e-68 | 223.6 | In-house | 1-233 (235) | alignment | ||
Range on Protein: 924-1154
Range on HMM: 1-233/235.0
NPAKNRYSDILPYDASRVPLKQIGAAEGdYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQDPGASKTFE
| ||||.|||||| .|| ||. . .. ||||||. . .. .||.||||..| .||||||. |.. ...||.| . .||..|.|.. . |.|..
nkkknRykdilpydktrvklkgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltyg
NFTVTCQ-SLV-DAQVYERRRLMVVPRSNVRgvkyEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLAD
...|... . | . | | | . . . . |. ........|||||.| ...|.|.....|... |. || |||||||||||.|||.| |.| .
dikvelkekekedekeytlrklelkkkkees....ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldille
AIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
. .....|| .| .|||.|. |||...||.|.|.|.
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 920-1155 | 1.8e-65 | 216.3 | In-house | 7-243 (249) | alignment | ||
Range on Protein: 920-1155
Range on HMM: 7-243/249.0
AARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPR---KCSPYFPQdpGA
.|. ||||.|||||| ||| |. .. .|||||.|.. | .||.|||||.| .|||||.. ... ..||.| .. || .|.|. |
llpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl..gg
SKTFENFTVTCQSLVDAQVYERRRLMVVPRsnvrgVKYEPLVTEHIWMKSWPDHGTP-EVESFLRCMQAVRRDFEE--PSGRVVVHCSAGVGRSGTFIAF
|.....||||. | . | .| |.... . |.. ||.. .|||||.| .|..|. ..||| .|| ..|.|.|||||||||.|||||
sleygdftvtllsvevkddytvrtleltnl.....ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
DMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
... . . . .|.. .| .||..|. .||. .||.|.||||.
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeall
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 922-1155 | 2.5e-65 | 215.6 | In-house | 7-240 (245) | alignment | ||
Range on Protein: 922-1155
Range on HMM: 7-240/245.0
RANPAKNRYSDILPYDASRVPLKQIGAAE-GDYINANYM--PNIGHRpYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQdpGAS
.|. ||||||||||| .|| |. .| . |||||.|. ..| .. .||.|||||.| .|||||.. ... ..||.. . || .|.|. | |
penkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..ges
KTFENFTVTCQSLVDAQVYERRRLMVVPRsnvrgVKYEPLVTEHIWMKSWPDHGTPE-VESFLRCMQAVRRDFE-EPSGRVVVHCSAGVGRSGTFIAFDM
.|...||||. | . | .| |.|.. ..|.. |.. .|||||.|. .|..|.....||. . ..|.|.|||||||||.||||| ..
ltygdftvtllseehlddytvrtlevtnl.....gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaayl
LADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
... . . .... .| .||..|. .||| |||.|.||||.
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeall
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 893-1156 | 5.6e-64 | 211.0 | In-house | 23-283 (293) | alignment | ||
Range on Protein: 893-1156
Range on HMM: 23-283/293.0
HASRLEEVYMRLRQEDEDLgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHS
|. | | .|.. ..| ... . .| |||||..|||||.||| |... .. |||||||.|. .| .||.|||||.| |||||||. ..|
sdlrfseeyeelkavgkdq...avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekks
PLVIMLCSINP---RKCSPYFPQDPGASkTFENFTVTCQSLVDAQVYERRRLMVVPrsnvrgvKYEPLVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRD
..|| . || |.|.| . .. . .|| .. . . . | |.. . | ... .|||||| || ...|. ...||.
siivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvaeeeledwvirelkiek.......ekeerkvrqyhftsWpdhgvPektktlldfvrtvrea
F--EEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
.. .. .||||||||||.||||| |.| .|| . .|. ..| .||..| ..||| .|| ||.... .
iektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 922-1155 | 9.3e-61 | 200.8 | In-house | 8-239 (243) | alignment | ||
Range on Protein: 922-1155
Range on HMM: 8-239/243.0
RANPAKNRYSDILPYDASRVPLkqigaAEGDYINANYMPNIGHrpYIAAQGPLPHTEDD----FWRMVYGEHSPLVIMLCSIN---PRKCSPYFPqdpgA
.| ||||||||||| ||| | .||||||... .. .|| |||||.| .| ||||.. ... ..||.. || .|.|
penlsknrysdilpydhsrvkl.....egsdyinanliyvtpr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp....g
SKTFENFTVTCQSLVDAQVYERRRLMVVPrsnvRGVKYEPLVTEHIWMKSWPDHGTPE-VESFLRCMQAVRRD--------FEEPSGRVVVHCSAGVGRS
..|...||||. | . | | |.... . ..... |.. .|||||.|. .|..|. ...|| . ..|.|.|||||||||.
evtygdftvtllseehlddytvrtlllen....ldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GTFIAFDMLADAIadghSMDVDAVVLQLRKHRRI-MVQTASQYQFIYEALK
||.|| ... . . ..|.. .| .||..| .||| |||.|.||||.
Gtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 915-1156 | 3.3e-60 | 198.6 | In-house | 30-274 (281) | alignment | ||
Range on Protein: 915-1156
Range on HMM: 30-274/281.0
RQTVKAAR--ANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPN-IGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS---INPRKCSPY
..| .|.. .| |||||.| |||.|| ... . . ||||||..| |.. |||.|||.|.. ..||.||. .. ...|. . || |
dntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrY
FPqDPGASKTFENFTVTCQSLVDAQVYERRRLMVvPRSNVrgvkyEPLVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEEPS-GRVVVHCSAGVGRS
.| |. .. .. ..||. .. . . | .|.... |.. |. |.. ..||||| |. . .| ..|.. |. . .|.||||||||.
WP.ddnselkygdvtvkstaeeekatyierkfkl.eresg.....etreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrt
GTFIAFDMLADAIADG-HSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
||.||.| |..|... ...||.||| .|||.| .|||| ||.|.| |...
GtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavld
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 895-1158 | 1.5e-59 | 196.6 | In-house | 20-280 (318) | alignment | ||
Range on Protein: 895-1158
Range on HMM: 20-280/318.0
SRLEEVYMRLRQEDEDLGYARQtvkAARANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPN-IGHRPYIAAQGPLPHTEDDFWRMVYGEHSPL
|.| | || ...| . .| ||||| .||.|| .|| |... | . |||||||.. .. |||||.|||.| .||||||. .| .
lllseeyerlsrseetvtslks...lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsav
VIMLCSINP---RKCSPYFPQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVpRsnvRGVKYEPLVTEHiWMKSWPDHGTPEV-ESFLRCMQAVRR-DF
..|| .. .|. |.|.. |..... .|. .. |. . | |.. | | .... . | . . ||||.|.|| |.| .. |.. .
ivmltqeeergkakvhryWPsk..gsrsygklvvelkeevelsdyvlrefkvt.r...teeeesrqvrqy.hytsWpdegvpesgaslldlvrqvskaqq
EEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPL
.. | .|||||||||| |.||| |.| . |.. .|| .| |||..| .|||| .||.|||..|.. |
ksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvlleal
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 885-1156 | 1.9e-58 | 193.1 | In-house | 17-288 (298) | alignment | ||
Range on Protein: 885-1156
Range on HMM: 17-288/298.0
TAEVMHLAHASRLEEVYMRLRQEDEDLGYARQTVKAARANPAKNRYSDILPYDASRVPLKQ-IGAAEGDYINANYMPNIG-HRPYIAAQGPLPHTEDDFW
.|.|.. . ....... ||.. ... . ..| ...| ||||.||...| ||| |.. . |.||||| .. . . ..||.|.||..| |||
laavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFW
RMVYGEHSPLVIMLCSINPR---KCSPYFPQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVrgvkyEPLVTEHIWMKSWPDHGTPEV-ESFLR
||| |.. ..|| ... |.. |.|.. ..|....||. .| . .. |.|.| ... . .. . ||||.|.||. .| |
rmvteedigtiVmltnleeldktkyhkywPde..gketygeitvsllskeefadlivrklkvskkkee.....kerevrqlhftsWpdkgvpenatsvld
CMQAVRRdFEEPSG--RVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
.. ||. .. .| |.|.||||||||||||| | . . . ...|| || |||.| .||| .|| ||||| .
llrkvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavle
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 915-1154 | 1.9e-58 | 192.8 | In-house | 37-275 (288) | alignment | ||
Range on Protein: 915-1154
Range on HMM: 37-275/288.0
RQTVKA-ARANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYF
... .. | |||| .||||| || ||. |. |||||.|. . ... |||.||||..| .|||..|| ... ..|| .. . .|| |.
ksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYW
PQDpGASKTFENFTVTCQSLVDAQVYERRRLMVVprsnvrgVKYEPLVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGT
|.. . | . ..||| .. . . . |.|... | . | . . ..||||| || . .| .. | .. .|...|||||||||.||
Pda.dkpknyGsvtvtlveskeledfvlrkllle.......kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgt
FIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
||| |.| ||. .|| ..| .|||.| .||| .||.||||.|
FialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 894-1155 | 2.9e-58 | 192.3 | In-house | 25-294 (306) | alignment | ||
Range on Protein: 894-1155
Range on HMM: 25-294/306.0
ASRLEEVYMRLRQEDEDLGYARQTVKAaRANPAKNRYSDILPYDASRVPLKQIGAAEGDYINANYMP---NIGHRPYIAAQGPLPHTEDDFWRMVYGEHS
. .|| . .|.||.. . |. . | |||| |||.| .|| ||. . .. |||||||. . .. |||.|| |..| ||||||. |.|
kagfeeefeelqqeeakkllsrkegak.penkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqens
PLVIMLCSINPR---KCSPYFPQDPGASKtFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYeplvTEHIWMKSWPDHGTPEVES-FLRCMQAVRRD
...|. . | ||..|.|. .. . . .||. | ... |. |.|.| ... . .. . |||||||.|. . .| .. |.|
rvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsvskkkkkkeere....vfqyhfksWPdhgvpkdpgavLdfledvnrk
FEEPS----GRVVVHCSAGVGRSGTFIAFDMLADAIADG---HSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
|| . | .|||||||.|| |||| |.| . | .|. .| ..|..| .|||..||.|.|.|.|
qeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 903-1156 | 5.6e-58 | 191.1 | In-house | 16-275 (290) | alignment | ||
Range on Protein: 903-1156
Range on HMM: 16-275/290.0
RLRQEDEDLGYA---RQTVKAARANPAKNRYSDILPYDASRVPLKQIGAAE-GDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLC
.|... | . .... . | .|||| |||||| ||| |..| | ||||||.. . |. |||||||||.| ||||||.. . .|.|.|
klkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaC
SI---NPRKCSPYFPQDPGASKTFENFTVTCQSLVDAQ-VYERRRLMVVPRSNVRGVKyeplvteHIWMKSWPDHGTPE-VESFLRCMQAVRRDFEEPSG
. . || |.|. . . .|..|.||... . . | | | ... | |. . ..|||||.|. ..| |. ...||. |. .
revelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvy.......qfhYtaWPDhgvPssaksllelielvrelqeseda
RVVVHCSAGVGRSGTFIAFDMLADAIADGHS---MDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
.|||||||||| || || |. ... ... .|| .||.|||.| .||| ||...|.|. .
PlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 923-1155 | 9.3e-57 | 187.2 | In-house | 27-265 (274) | alignment | ||
Range on Protein: 923-1155
Range on HMM: 27-265/274.0
ANPAKNRYSDILPYDASRVPLK-QIGAAE-GDYINANYM--PNIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDPGA-
. |||| .||| . ||| |. . . .| .||||||. .. .. |.|.|||||.| .|||||.| |......|| . | .||. |||.. ..
gsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedye
-SKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGvkyeplvTEHIWMKSWPDHGTPE-VESFLRCMQAVRRDFEE---PSGRVVVHCSAGVGRSGTFI
|...... .. .. |. . |. |.|.. .. | |.| .|||| .|. ....|. .. |... || . . ||||||||.|| | ||
iserygdveikvekiverndysvrklvlkylerers.......vkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfi
AFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
| .. . . . .|| .| .|| .| ||||..||..|..||
aisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 887-1154 | 5.5e-56 | 184.5 | In-house | 7-276 (288) | alignment | ||
Range on Protein: 887-1154
Range on HMM: 7-276/288.0
EVMHLAHASRLEEVYMRLRQEDEDLgYARQTVKAARANPAKNRYSDILPYDASRVPLKqigAAEGDYINANYMPNIGH--RPYIAAQGPLPHTEDDFWRM
.. | . |.... |.|... ... .|. .. |||. |||||| .|| |. . ||||| .. .. ..||.|.||. | |||.|
qrkmldgktaldkkfkeleqkqdke.arkrsiaiaklyseknrsrdilPyDhnRvklr...gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlm
VYGEHSPLVIMLCSIN---PRKCSPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMVVPRsNVRGVKyeplVTEHIWMKSWPDHGTPE-VESFLRCM
|| ..|....|| | . |.. |.|.| |....|....||..| ... . .| | . . ... || |. ..|||..| |. |..|. .
vyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletl.dadavk....svshlqltsWpelGvPasPetllqfl
QAVRRDFEEPSGR----VVVHCSAGVGRSGTFIAFDMLADAIADGHSM-DVDAVVLQLRKHRRIMVQTASQYQFIYEAL
..|. .|. . .||||||||||.|.| . .. |. . |. || .||. || |||. .|..| |||
devesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 888-1156 | 2.7e-54 | 179.4 | In-house | 15-281 (305) | alignment | ||
Range on Protein: 888-1156
Range on HMM: 15-281/305.0
VMHLAHASRLEEVYMRLRQEdEDlgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQIGAAE-GDYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMV
.. ... ||. | | .| |. |. || ||||...| ..| .|. |.. . |||||.|. . ||.|||||..| .||||..
earvysdkgleaqykslyee.ee....sidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrli
YGEHSPLVIMLC---SINPRKCSPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNvrgvKYEPLVTEHIWMKSWPDHGTPEV-ESFLRCMQ
. |. ..||. . || |.|. . .| |..|.|. .| |. | |.| . ... . | . . . .||||| |. |.|. ..
veekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiede....dkesrtvlqyqltdWPdhGvpqfatsllslik
AVRRDFEEPSG-RVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
|..| .. | ..|||||||||.|.||| |. . . ..|| |. |||..| |||| ||.|...||..
rvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdalde
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 888-1156 | 7.7e-54 | 177.9 | In-house | 16-281 (319) | alignment | ||
Range on Protein: 888-1156
Range on HMM: 16-281/319.0
VMHLAHASRLEEVYMRLRQEDEDlgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNIGHR-PYIAAQGPLPHTEDDFWRMV
.. . ||. .. |.. ..| . | ||||..||.|| .|| |... . |||||... .| .||.|.|| .| .||||||
alastgetllekefkllkeavnd....tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmv
YGEHSPLVIMLCSINPR---KCSPYFPQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNvrgvKYEPLVTEHIWMKSWPDHGTPEV-ESFLRCMQ
. |.| |.||. .. . |.. |.|. ... ...|| .. . |. |.|.. ..|. . | | ..||||. || | | ..
Weeessivvmltklveklkvklkkywpee..nfeeyGrlivtleeeeeledyiirklklnkkss....evetRevkhfqyteWpdhdvPekatslldllk
AVRRDFEE-PSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
.|. |. || .|||||||||| ||||. |. . . .|| .| .|| | ||||. .||.|||||| .
rirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealle
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 913-1156 | 9.6e-54 | 177.6 | In-house | 36-284 (307) | alignment | ||
Range on Protein: 913-1156
Range on HMM: 36-284/307.0
YARQTVKAA-RANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN--PR-KCSP
..|. .. | |||| || ..| || ||.| | .. |||||... .. .||||.|. | .|||||. .. |..|| .. .| ||.
idkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcak
YFPQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVPRS-NVRGVKYEPLVTEHIWmKSWPDHGTPEV-ESFLRCMQAVRRDFEEPSGRVVVHCSAGVGR
|.|.. . ... |.. | .. | .| | | .. |. . |. . . ..|.| ||| .. |. .. || . . .||||||||||
YWpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhy.tgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgr
SGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
||.|.|.|.| . . ...|. ..| .||..| ..|| ||.|.| || .
sgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralld
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 890-1156 | 9.9e-54 | 177.5 | In-house | 14-285 (563) | alignment | ||
Range on Protein: 890-1156
Range on HMM: 14-285/563.0
HLAHASRLEEVYMRLRQEDEDLGYARQtVKAARANPAKNRYSDILPYDASRVPLKQIGAAEG--DYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMVY
| ...| . | .| . . .. | ||||..|..|| ||| |... .. |||||||. .. .||.||||..| ||||||..
hadgdigfseefealqsetiskdldae.hsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiW
GEHSPLVIMLCS---INPRKCSPYFPQdpGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVK--YEPLVtEHIWMKSWPDHGTPEVESF-LRCM
... ...|. . ||| |.|. |.|.....|| .. .| |.|.. . .. . .| || . . .|||||.|| . . | .
eqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklv.rqyhytkWPdhgvPehslpvLifv
QAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. . .. | .||||||||||.||.|..| | | . ....| .. ..| .| .||| ||.|...|| .
kkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalle
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 905-1169 | 6.5e-53 | 174.6 | In-house | 25-287 (314) | alignment | ||
Range on Protein: 905-1169
Range on HMM: 25-287/314.0
RQEDEDLGYARQTVKAaRANPAKNRYSDILPYDASRVPLKQIGAA-EGDYINANYMPNIgHR--PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP
..| | | .. | | .|||. |||.|| ||| |..| . |||||... .| .|..||||..| ||||.|| |.. ..|| .
keeyeslfegwdaakk.denreknrsgdilaydrsrvflitidgdpssdyinaalidsy.krpaafivtqgPlqetvkdfWrlvydencasivmltelve
RK---CSPYFPQDpgaSKTFENFTVTCQSLVDAQVYERRrLMVVPRsNVRGVKYEPLVtEHIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEEPSGRVVVH
|. |.|.| ....... |.. . . . | .. | . ||.. .| .. .||||..| ...|. .. | || ||.|||
vgrvkClkyWPed...tevygdikvelvetellaelvvr.ifrvek.largqeeirev.rqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvh
CSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNpLCVCVCVCVCVC
|||| ||.||||| |.. | | . .|| .| .||... ||.| ||.|||... . |.| .. |.
CsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile.aclcgetaipvs
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 915-1159 | 1.6e-52 | 173.3 | In-house | 34-277 (515) | alignment | ||
Range on Protein: 915-1159
Range on HMM: 34-277/515.0
RQTVKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFP
||| | |||| .||||| .|| |. | . . ||.|| |.| . . |||.|||.. . |||||.|. |. ..|. . ||. |.|
pqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWP
QDPGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGvkyeplVTEHIwMKSWPDHGTPE-VESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTF
. || | | .. | || .|.| |. ...| || . .. |||.|.|. |.|. ...|. | .. . ...|||||||| | .
dkpgdsvkfGsikvelvsleactggikrkltvlkgddsrt......vtqfh.fteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvv
IAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPLC
|. | .......|| .| ..|..| .||| || |||.|... |
isidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 916-1156 | 1.7e-52 | 173.3 | In-house | 48-293 (330) | alignment | ||
Range on Protein: 916-1156
Range on HMM: 48-293/330.0
QTVKAA--RANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNIGHR-PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPR---KCSPYF
|...| | |||. .||||| ||| | .. | | ||||| .. .. .||||||. .| .|||||.. .| ..|| .. | || |.
atlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqyw
PQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYEPLVTeHIWMKSWPDHGTPE-VESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGT
|.. . |. | .|. . . .. | | ..| .. . | . ||. . ..|||| | | |. ...|.. . .| .||||||||||.||
Pde..GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvr.qfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGt
FIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
||..| . . . . .|| .| .||. | |||| ||.|||..|..
fivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlle
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 917-1155 | 1.9e-52 | 172.9 | In-house | 13-261 (270) | alignment | ||
Range on Protein: 917-1155
Range on HMM: 13-261/270.0
TVKAARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMP--NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQ
.. .| ... ||| |||| |.|| |... . ||||||.. . .. ||||.|||| | .||||.. |... ..|. .. .||. |.|.
dlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa
DPGASKTFENFTVTCQSL--VDAQVYERRRLMVVPRSNVRGvkyepLVteHIWMKSWPDHGTPEVES-------FLRCMQAVRRDFEEPSG--RVVVHCS
.|. . ..|. ... .| . .. | ..|| . ... | || | |...||||| |. | |....|||| .| . ..||||
epkekvkledgkikvlalseekeegyiltrlrleekgeerr.....lv..HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcs
AGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
|||||.||.|| |. .. ...|| |.. .|||.| .||. ||.|.|.|.
aGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 921-1154 | 2.9e-51 | 169.0 | In-house | 38-271 (280) | alignment | ||
Range on Protein: 921-1154
Range on HMM: 38-271/280.0
ARANPAKNRYSDILPYDASRVPLKQigaAEGDYINANYM----PNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQdP
.| .|||| ||||||| || ||. .| |||||||. | | |||.||||..| |||.||. ..| |..|| .. || |.|. .
kpenlsknryrdilpydatrvklke...setdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe.t
GASKTFENFTVTCQSLVDAQVYERRRLMVVPRSnVRgvkyEPLVTEHIWMKSWPDHGTPEVE-SFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAF
. . .. .|.|.|.. . | | |.. .. . | .. .||||| |. . .||. .. ||. . . ||||||||.||.| .|..
edeleygefsvkcekedetksyvlrelvlkdke.tk....eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlill
DMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.. | ... . ..| ..| | ..|||||||.|. ||.
etalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 920-1154 | 6.1e-51 | 168.3 | In-house | 33-265 (273) | alignment | ||
Range on Protein: 920-1154
Range on HMM: 33-265/273.0
AARANPAKNRYSDILPYDASRVPLKQIGAaegdYINANYMP-NIGHR--PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQDPG
..| .|||| ..||||..||.|.. |. ||||... ..|. |||.|||||.| .|||.||. .. ...|. . || |.|. .
kkkenkdknryrnvlPydetrvklgdegg....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPeskn
ASKTFEN-FTVTCQSLVDAQVYERRRLMVVPrSNVRGVKYeplvTEHIWMKSWPDHGTPEVESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFD
. . .| ..|. ... . . |.|.| |. . .. |. . .|||||.| | . | | ... .| .|||||||.|||||.|. |
kklkvsnrlevellkvqkldgfvvralavkd.sesgesre....vahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitid
MLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.. . |. ...|| .| .||. |. .||| || |.|.|.
vvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykai
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 913-1159 | 7.4e-51 | 167.9 | In-house | 33-278 (315) | alignment | ||
Range on Protein: 913-1159
Range on HMM: 33-278/315.0
YARQTVKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI--NPR-KCSPY
||.| . | |||| .|||.| .|| |. | . ||||| |.. . . . |||.||||. . |||||||..|. ..|. . . || |
iyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqy
FPQDPGASKTFENFTVTCQSLVDAQVYERRRLmVVPRSNvrgvkYEPLVTEHIwMKSWPDHGTPE-VESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSG
.|. . | | .. |. || |.| |. .|. || . .. |||.|... . |.|. ...|. | .. ..|||||||||.|
wPdrkadsvefGsikvellsleadtdgvarkl.vtrkse.....esrtvtqfq.ftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtG
TFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPLC
.|. | . |....|.|| .| .||..| .||| .| |||.|... |
vvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 915-1158 | 1.4e-49 | 163.9 | In-house | 42-284 (297) | alignment | ||
Range on Protein: 915-1158
Range on HMM: 42-284/297.0
RQTVKAARANPAKNRYSDILPYDASRVPLKQIGAA-EGDYINANYMPNIGHRpYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP--RKCSPYFPQD
||| . | |.||..||||| ||| |. .. . ||.|| ... . || .|. | | . | .|||.||. |. ..|| | .|| |....
pqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkhr.littqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdk
pgASKTFENFTVTCQSLVDAQVYERRRLMVvPRSNVrgvKYEPLVTEHIWMkSWPDHGTPE---VESFLRCMQAVRRDFEEPSG-RVVVHCSAGVGRSGT
...|| . .|. .|. . . . .| | | ... | . .| . .. .|||. .. ..|.| .. || ||.. . ..|||.||||| |
..gvttfGdvsvvllsvsereGfikrelev.tkgka...karrvvkqyqfv.eWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgv
FIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPL
... | . . ...|. .| .||..| .||| ||.|.|.|. . |
lltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 920-1157 | 1.4e-49 | 163.5 | In-house | 5-241 (250) | alignment | ||
Range on Protein: 920-1157
Range on HMM: 5-241/250.0
AARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN--PRKCSPYFPQDpgAS
.| ||||.||...| ||| |.. | ||||| .. ... .||.||||..| ||||||. |.| ..|| ... .... |.| . .
kkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPve..ka
KTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVkyeplVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEE-PSGRVVVHCSAGVGRSGTFIAFDM
... . ||. | |. |.|.. ... . . .. .||| | ||| .. | .. |.. .. .. |.|.|||||||||.||| |
ekyGdvtvsllskeefadytkrklklskakkader.....ivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaida
LADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNP
. . . . .|| |. .|||.| .|.. .|| |.||....
vlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 874-1155 | 1.7e-48 | 160.6 | In-house | 13-288 (319) | alignment | ||
Range on Protein: 874-1155
Range on HMM: 13-288/319.0
VASFEADYQHVTAEVMHLAHASRLEEVYMRLRQEDEDLgyARQTVKAARANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNIGH-RPYIAAQ
| |.| ||... . ..|| . |. . .| | || | |||. .||..| ..| |... | ||||| .. . |||||
vpdfpayyqqlsnksdfdddltklevefrracklgvnl..adqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaq
GPLPHTEDDFWRMVYGEHSPLVIMLCsinPRKCSPYFPQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYeplVTeHIWMKSWPDHGTP
|||. | .|||||.. .. ...| ||| |.|.. . .. |.| | .|. ... | | . . .. .... .| .. |||.| |
GPldntladfWrmiweyncstivllt...kdkcsqywplk..ivikeerfkvkvdsveetaeyvvrdielsedgkekdirk...it.qfhflGwpdvGvp
EVESFLRCM-QAVRR--DFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
. | | .. . || . |. .||||||||||.|..|..|.| | . . . .|| .| .||. | .|| ||.||| ||
dypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysall
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 922-1158 | 3.7e-48 | 159.1 | In-house | 47-279 (315) | alignment | ||
Range on Protein: 922-1158
Range on HMM: 47-279/315.0
RANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDpgaSK
| |||| .|..|| ||| | . . ||.|||... .| |||||||.. . .||||.|. |. ..|| .. . ||. |.| .
ienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kv
TFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKyeplvteHIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLA
.. ..||| .| . | | | || ..|.| | . . |||| | |. ... .. |.. .. | .||||||||||.||||..| .
iyGkitvtrkseevnteytvrtlsvvfgdnirevv.......qlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavl
DAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPL
| . . .|| .. ..|. |. |||.| ||||||.|| . .
dqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 895-1154 | 3.8e-48 | 159.0 | In-house | 16-286 (297) | alignment | ||
Range on Protein: 895-1154
Range on HMM: 16-286/297.0
SRLEEVYMRLRQEDEDlGYARQtvKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPL
. | . |. .|.| | . . ||| ||||.|.| || .|| |... . ||||||.. .. .||.||||..| .||||||. ..
rGlskeyaeirnepve.Gtfla..sklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlv
VIMLCSIN---PRKCSPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMVvprSNVRGVKYEplVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRD--
..| . .||. |.|.. ..|. | ...|. . . . |. | | . .||. . | . ||||.|.|. .|.| ...||.
ivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvlei...knvkteesr..kvthfqflsWPdyGvPssaaslldvlekvrekqa
-----------FEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.. .|||||||.||.||||..|. . . . .|| .| .||. | ..|| ||.| | |.
lavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 895-1154 | 3.1e-47 | 155.7 | In-house | 6-267 (290) | alignment | ||
Range on Protein: 895-1154
Range on HMM: 6-267/290.0
SRLEEVYMRLRQEDEDLGYarqTVKAARANPAKNRYSDILPYDASRVPLKQigaAEGDYINANYMP-NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLV
. .|.|. .|.| .|. .. .| ..||| |. ||| ||. |.. |. |||||. . . .| || .|||||.| | ||.||. ..| |
rlykeiyldirkeasdfpt...reaklpenrnlnryrdvspydhsrikler...adndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskav
IMLCSI---NPRKCSPYFPQDPG-ASKTFE--NFTVTCQSLVDAQVYERRRLMVVPrsnVRGVkyEPLVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRD
.|| . . || |.||. . ..| ...|. | . . | .| | . .. | . | .||| | || .||. .. ||.
vmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelen...lktq..etreilhfhyttwpdfgvpespaaflkflfkvres
--FEEPSGRVVVHCSAGVGRSGTFIAFDMLA---DAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
. . | .|.|||||.||||||. | . .. | |.|. |.|.|||.| ..||| | .| | |.
GslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylai
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 914-1155 | 5.7e-47 | 155.6 | In-house | 15-252 (284) | alignment | ||
Range on Protein: 914-1155
Range on HMM: 15-252/284.0
ARQTVKAARANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCsinPRKCSPYFPQD
. || | |||. .||..| ..| |... | ||||| .. . |||.||||. | .|||||.. .. ...| ||| |.|..
tdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt...kdkcsqywplk
pgASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYeplVTeHIWMKSWPDHGTPEVESFLRCM-QAVRR--DFEEPSGRVVVHCSAGVGRSGTF
. .. |.| | .|. ... | | . . .. .... .. .. |||.| |. | | .. . || . |. .||||||||||.|..
..ivikeerfkvkvdsveeseeyvvrdielsedgkekdirk...ir.qfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvy
IAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
|..|.| | . . . .|| .| .||. | .|| ||.||| ||
ivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysall
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 913-1154 | 8e-47 | 154.7 | In-house | 38-292 (300) | alignment | ||
Range on Protein: 913-1154
Range on HMM: 38-292/300.0
YARQTVKAARANPAKNRYSDILPYDASRVPLKQIGAAEGDYINANYMP---NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSP
| .. . | |||. |.|||. .|| |. .. .|||| . .| ||.|||||..| |||.||. .. |..|| .. |.
dallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfk
YFPQD--PGASKTFENFTVTCQSLVDAQVYERRRLMV--VPRSNVRGVKyeplvteHIWMKSWPDHGTPE-VE---SFLRCMQAVRRDFEEPS------G
|||.. . .|..| || . |.. . . | . .| .. | | |. . ||||| || |. |.|. .|.||| ... .
yfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvw.......hlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskP
RVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
|.|||||||||.| | |.| .. ....|.. |. .||. | ..||| .||.|.|..|
PvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 916-1156 | 5.6e-45 | 148.9 | In-house | 40-286 (325) | alignment | ||
Range on Protein: 916-1156
Range on HMM: 40-286/325.0
QTVKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMP-NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP--RKCSPYFPQD
..| . .| ||||. .....| ||| |. . ... |||||.|. ... ..||| ||..| .|.||.|. ....|..| .. .|. |.|..
kkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdrcavywpke
PGASKTFENFTVTCQSLVDAQVYERRRLMVvprsnvRGVKY-EPLVTEHIWMKSWPDHGTPEV----ESFLRCMQAVRRDFEE---PSGRVVVHCSAGVG
| |||| . | ... . | |.| | ..|| | . . ..||.| |... |.|. ..|| |. ..||||||||
mgksktfGglevklrtieeisdyvhrvldv......kqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvG
RSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
|.|.||.. ... . . ..|. .| .|||.| ||.|. || .||||| .
rtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealve
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 923-1154 | 5.8e-44 | 144.9 | In-house | 53-279 (290) | alignment | ||
Range on Protein: 923-1154
Range on HMM: 53-279/290.0
ANP--AKNRYSDILPYDASRVPLKQigAAEGDYINANYMPNIgHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQDPGASKT
.|. |||| |. | .|| ||. .|||. |||. . . ..| .||.| | |.|||| |. ..||| . ||..|.|. | |
kntefkknrykdvvcndktrvilkd..GydGdyvhanyvkGl.kamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevlt
FENFTVTCQSLVDAQVYERRRLMVVprSNVRGVKYEPLvtEHIWMKSWPDHGTPEVE-SFLRCMQAVRRDfeepSGRVVVHCSAGVGRSGTFIAFDMLAD
| ..||.| | . .... | .. | | |. .|||||. . . ..|| ....|. || ||||||||.||.|||.| .. ..
fGeitvlcseeddkdaniikktlsv..rdkdsGkehkl..khlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrtGtfvaievglq
AIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
. ||...|. .| ||. | || || . |.|
illdGkeldlldlvralrnsrlnsvqvdiqylalveil
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 924-1154 | 6.7e-44 | 145.0 | In-house | 1-167 (182) | alignment | ||
Range on Protein: 924-1154
Range on HMM: 1-167/182.0
NPAKNRYSDILPYDASRvplkqigaaEGDYINANYMPNIGHR-PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCsinprkCSPYFPqdpgasktfenft
| ||||||||||| || ||||||.. . .||.||||..| ||.||..... ....|. . .|.|
nldknrysdilpydhsr.........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt......eelywp.............
vtcqslvdaqvyerrrlmvvprsnvrgvKYEPLVTEHIWMKSWPDHGTPEVESFLRCMQAVRRdfeePSGRVVVHCSAGVGRSGTFIAFDMLADAiadgh
.... ... .|||||.|.....|. ...|.. ..|.|.|||||||||.||..| ...
............................ellerlgiqylylpwpDhgvpdldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....
SMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
..... .| ..|..| ||.| .||.|.. ||
gvsleeavklvrsrRpgmvitpnqyfflqlal
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 916-1165 | 4.3e-43 | 142.2 | In-house | 25-274 (283) | alignment | ||
Range on Protein: 916-1165
Range on HMM: 25-274/283.0
QTVKAARANPAKNRYSDILPYDASRVPLKQIGAaegDYINANYMP----NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYF
....|. |. |||. .|.|.| || || ||||| ..| . . ||.||.|| .| |||.||. |. ..|| . ||| |.
adiasadenkrknrnqeivpadqwrvelksesr...dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyW
PQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVPRsnvrGVKYEPLVTEHIWMKSWPDHG-TPEVESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGT
|.. |. . .|||| . . . . .. |.. . . |. | . | . | . ..|... . . |.. | .|||||.|.||...
Pkr..GsedyGeftvtlrkettsnsfiikelllrvn....ssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtav
FIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL-KNPLCVCVCVC
||| . . .|| ||| .|..| .||| ||....|. .. || .
fiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqia
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 892-1154 | 1.7e-42 | 140.3 | In-house | 17-279 (290) | alignment | ||
Range on Protein: 892-1154
Range on HMM: 17-279/290.0
AHASRLEEVYMRLRQEDEDlgyARQTVKAARANPAKNRYSDILPYDASRVPLKQIGAAEG---DYINANYMPN-IGHRPYIAAQGPLPHTEDDFWRMVYG
.. .. ...| . ... ||. . | .||...|..|| |..|..|. . .|||| |. . .. |||.|||...| |||....
kgnegfrnqfkmldsgese...htvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwq
EHSPLVIMLCSIN---PRKCSPYFPQDpgASKTFENFTVTCQSLVDAQVYERRRLMVVpRSNVRgvKYEPLVTeHIWMKSWPDHG-TPEVESFLRCMQAV
|... ..||..|. || |.|. .|....|... .. . | .|.| | .| ... || . ...|...| .. .. | .. .
ekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllneetlneyierklevk.nknsa..gakqsvt.qyqitnwdstgkvtnpqtillvieem
RR-DFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
. . . . .|||||..||||..|.| .. . .|| .|. ..| . .|||. |||.|.. .
yktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqiv
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 951-1157 | 7.4e-41 | 135.9 | In-house | 4-224 (272) | alignment | ||
Range on Protein: 951-1157
Range on HMM: 4-224/272.0
GDYINANYMPNIGH----RPYIAAQGPLPHTEDDFWRMvYGEHSPLVIMLCSIN---PRKCSPYFP----------QDPGASKTFENFTVTCQSLVDAQV
..||||.... |. . .....||||.|..||||. . .. ...|.| . ||..| | | . .. ...||..| . .
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
YERRRLMVVPRSNVRGVkyepLVTEHIWMKSWPDHGTPEvESFLRCMQAVRRdfeepSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMD--------
| |.|... .. . . |... .|||||.|. |..|. ...... .|.|.||||||..|.||..| ..|. . . .|
yilrellltlllsagea....revmhlhytdwpdhgvpq.eallellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
VDAVVLQLRKHRRIMVQTASQYQFIYEALKNP
....| .||..|. .||| ||.|.||||..
leeaveelraqrpgavqteeqylflyeallel
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 915-1156 | 1.2e-40 | 134.3 | In-house | 38-276 (287) | alignment | ||
Range on Protein: 915-1156
Range on HMM: 38-276/287.0
RQTVKAARANPAKNRYSDILPYDASRVPLKqigAAEGDYINANYMPNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQ
|.. | | |||...||..| ||.|| . ||||| .. .. .|.|..|. .| .||... .. . ..||| . ..| |.|.
evthniasqnkdknRltqilvpdnyrvllk...gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpe
DPGasKTFENFTVTCQSLVDAQVYERRRLMVVpRSNVRGvkyEPLVTEHIWMKSWPDHG-TPEVE-SFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTF
. .. ..... . . | |.| | ..| | ... . . .|...| .| . ..| . .. . . . .|||||..||||..|
eks..vvlGeyniellneevnagyierklevk.nknkag...dkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamf
IAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
.| .. . .|| |. . | . .|||..||.||.... .
caaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 921-1156 | 1.1e-39 | 132.4 | In-house | 43-278 (314) | alignment | ||
Range on Protein: 921-1156
Range on HMM: 43-278/314.0
ARANPAKNRYSDILPYDaSRVPLKQIGAAEGDYINANYMPNIghRPYIAAQGPLPHTEDDF----------WRMV--YGEHSPLVIM-------------
.|. |||| ||||.| .|| |. . |||||.|. .. . .||.||||..| .|| |||| . .. . |
lflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf..lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrL
--------LCSINPRKcspyfpqdpgASKTFENF---TvtcqslvdaqvyerrrlmvvprsNVR--GVKYEPLVTEHIWMkSWPDHGTPEVESFLRCMQA
|... .. . |.... .. . ..| |. ..... .||...| | |......
daAlgKtpllildgng..........neptaadlellk.......................eelydpelferlgikylri.pvpDgsaplledfdeflef
VRRDfeEPSGRVVVHCSAGVGRSGTFIAFDMLADAIadghSMDVDAVVLQLRKHRR-----IMVQTASQYQFIYEALKN
... .. |.|.|||.||.||.|||.. ..| . .... .. ..|. | .... ||.||.|||..
ieea..dkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealle
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 914-1158 | 2.8e-39 | 129.6 | In-house | 35-236 (392) | alignment | ||
Range on Protein: 914-1158
Range on HMM: 35-236/392.0
ARQTVKAARANPAKNRYSDILPYDASRVPLKQIG-AAEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRKcspyfpqd
.||| | |||| .|||||..|| |. | .. ||.|| |.|.. . |||.||| . . |||||||. |. ..|. ..
ypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd........
pgasktfenftvtcqslvdaqvyerrrlmvvprsnvRGVKYEPlVTEHiWMKSWPDHGTPE-VESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIA
.| .. |. . . |||.. |. . |.|. .. |. || . . ...||||||||.| |.
....................................kgddart.vaqf.hftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvis
FDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPL
| . . .|| .| ..|..| |||| || ||| |. . |
idsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 916-1154 | 3.1e-39 | 129.8 | In-house | 33-273 (307) | alignment | ||
Range on Protein: 916-1154
Range on HMM: 33-273/307.0
QTVKAARANPAKNRYSDILPYDASRVPLKQIGAAeGDYINANYMP-NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQD
||.| .||. ||||.|. | .|. .| |.| ||| |||. | . .|.||||| | .|| |. |. ||||| . || |.| .
vtveafsantdknryqdvkcqdkgrivvkfdgla.sdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywple
PGASKTFEN--FTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYEPLVTeHIWMKSWPDHGTPEVE-SFLRCMQAVRRDFEePsgrVVVHCSAGVGRSGTF
| ..| . |.. . | .. |. | .| . .. |. . |||.|.|... . . ..||| | . | ||||||||||||||
egqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiq.hlqwenwpdrgvpqinltainlleavrydtn.p...vvvhcsaGvGrsGti
IAFDMLADAIADGH-SMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.| .. | . .| .|.. .| .||..|. .|| || ... |
vaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 884-1155 | 3.7e-39 | 129.2 | In-house | 12-274 (287) | alignment | ||
Range on Protein: 884-1155
Range on HMM: 12-274/287.0
VTAEVMHLAHASrlEEVYMRLRQEDEDLGyarqtvkaaranPAKNRYSDILPYDASRVPLKQIGAAEGDYINANYMPNIG-HRPYIAAQGPLPHTEDDFW
| .|| | . | | . . ... .| ||||.|.||.| .|| | . | |||||||.. . .||||||.. | |||
vdkevdalkeds..esstatfkaaeelaa............vkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfw
RMVYGEHSPLVIML---CSINPRKCSPYFPQDpGASKTFENFTVTCQSL--VDAQvYERRRLMVVPRsNVRgvkyEPLVTEHIWMKSWPDHGTPEV-ESF
|.|. ..| ||.. || |.|. ..|. . . . | | | .. . | | | . . . ||||.. . ..
ravletrsasvitmtreveearlkcykywPer.evPmrvGGysvvlldydikePe.ygvralrlidl.etr....earvvkqldllswPdkvlaPtavgl
LRCMQAV------RRDFEEpSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
.| . | .|| .| | .|||...|.||||...| .| . | .|| |||..||..|. .||.. |....||||
irfvldvkqhielardase.vGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 951-1152 | 4.3e-39 | 129.4 | In-house | 5-155 (172) | alignment | ||
Range on Protein: 951-1152
Range on HMM: 5-155/172.0
GDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSInprkcspyfpqdpgasktfenftvtcqslvdaqvyerrrlmvvprsNVRG
|||||.|.. . . .|| ||||..| .|||||.. .. ....|.. . .
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..............................................lydp
VKYEPLVTEHIWMkSWPDHGTPEVESFLRCMQAVRR-DFEEPSGRVVVHCSAGVGRSGTFIAFDMLAdaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQ
..|.|. ..... .|||||.| | .|.... ... ..|.|.|.|||||||||.||..| ... ...... .| ..|..|...||. |||.
ellerlgiqylyl.pwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
FIYE
|.|.
flyy
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 890-1154 | 4.6e-37 | 122.3 | In-house | 24-288 (297) | alignment | ||
Range on Protein: 890-1154
Range on HMM: 24-288/297.0
HLAHASRLEEVYMRLRQEDEDLgYArQTVKAARANPAKNRYSDILPYDASRVPLKQIGAA-EGDYINANYMPNIGHR--PYIAAQGPLPHTEDDFWRMVY
|| . .|||. . | . . . . ..| | | |||....|||| ||| ||. .| . ||||| . . | |||.||||..| |||.||.
hlknkdrlekewealcayeaep.st.kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvw
GEHSPLVIMLCSINP---RKCSPYFPQDpGaSKTFENFTVTcqsLVDAQVYERRRLMV-VPRSNVRGVKYEpLVTEHIwMKSWPDHGTPE-VESFLRCMQ
. . ....|.... ..|. |.|.. | |.... . | || .. |. |.. . || |||..|.| |.| .
eqGvvvivnltrleeegvkqckrywpde.G.sevyhiyevh...lvsehiwcddylvrsfylknlqtsetr.tvtqfh.flswpeegvPasaksllefrr
AVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADG-HSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
| . . | .|||||.|.||.|..|. |.. . .. | . .|. | . || | .|.| .|..|.. |.
kvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltav
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 924-1153 | 5.7e-37 | 122.2 | In-house | 3-234 (237) | alignment | ||
Range on Protein: 924-1153
Range on HMM: 3-234/237.0
NPAKNRYSDILPYDASRVPLKQIGAAeGDYINANYMPNIGHRP--YIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDpGASKTF
| .||||..| || ||| || |.. |||||.|. .. | |||||||| . ||||.||. |. ...|| . | || |.|. ...
nkiknrygnivaydhsrvvlkgagsg.sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpaay
ENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKyepLVtEHIWMKSWPDHGTPEVE-SFLRCMQAVRRD--FEEPSGRVVVHCSAGVGRSGTFIAFDMLA
.||. . . | | |... | ....|. |. . ||||.| |. ..|| . . || ..||||||||.| |. | .
gvltvslkkkeefsdytvrslllskrltlkevr...li.hqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidaml
DAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEA
. . .|. | . . | ..|| || ||...
rqakekkvvdiynyvysieedrpyiiqtkdqyvfihqt
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 952-1155 | 2.8e-36 | 120.3 | In-house | 13-170 (176) | alignment | ||
Range on Protein: 952-1155
Range on HMM: 13-170/176.0
DYINANYMPNigHRpYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDPGASKtfenftvtcqslvdaqvyerrrlmvvprsnvr
||||||.. .| .|| |||||.| ||..|.. .. .|..|.. . || |.|. ...
dyinanlilg..sr.piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi................................
gvkyeplvteHIWMKSWPDHGTPEVESFLRCMQAVRRDFEEPsGRVVVHCSAGVGRSGTFIAFDMLADaiadGHSMDVDAVVLQLRKHRR-IMVQTASQY
... |||||.|. | .|......|. .| |.|.||||||.||.||..| ..| .. ..|. .. ..|..|. .||| .||
..........qylhlpwpDhgvpdlelllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQy
QFIYEALK
.|.||...
rflyefel
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 917-1156 | 6.4e-36 | 118.7 | In-house | 41-277 (439) | alignment | ||
Range on Protein: 917-1156
Range on HMM: 41-277/439.0
TVKAARANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPN-IGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI-NPRKcspYFPQDpg
.. | . .|||| |. ..| .|| |..| | ||||||. . |||.||| .| |||||.|. ... ..||. . . | |.| |
slaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk...ywpsd..
ASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNvRGVKYEPLVTEHiwMKSWPDHGTPEVES----FLRCMQAVrRDfEEPSGRVVVHCSAGVGRSGTFI
| . . .| .. .. | | . |. . . .. | .. | .|||. | | |||.... | .| | |||||||||||.|| |
aevcygdiavrvdrnielpnyvirgfkvfnerd.ttekertvlqfh..yiawpdknvpaqashvldflrainsa.nd.keeygpvvvhcsagvGrtGtii
AFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
|.|. . . .|.. .| |||.|. |||. || |||.|. .
aldialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 922-1156 | 8.3e-36 | 118.1 | In-house | 40-288 (296) | alignment | ||
Range on Protein: 922-1156
Range on HMM: 40-288/296.0
RANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN-PRK-CSPYFPQDPgaSKT
| |||. ...||| || |... | .. ||||| |. .. || ..| .| |.|||.|| |.. |..|. .| . |.|.. .
kenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnks..keq
FENFTVTCQSLVDAQVYERRRLMVVPR-----SNVRGVKYEPLVTEHIWMKSWPD-HGTPEV-ESFLRCMQAVRRDFEEP-----SGRVVVHCSAGVGRS
. .. | . . | . .. . .. ..|| | . .. .. |. . | . .... .. || |. | |||..| |..||
ygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRs
GTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
| ..| |. . . . .|| | .||..|. .|.. .|..||. |..
GvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlle
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 891-1157 | 1.2e-35 | 117.7 | In-house | 11-292 (301) | alignment | ||
Range on Protein: 891-1157
Range on HMM: 11-292/301.0
LAHASRLEEVYMRLRQEDEDlgyaRQTVKAARANPAKNRYSDILPYDASRVPLKQI---GAAEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVY
.|. ..|| | .|...... . ||. .| | ||. .| .|| |. ||. .. .||||.|. .. . . .||||||. .| ||||...
akhsnkfeeqykelkegedk....sctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliw
GEHSPLVIMLCSINPR---KCSPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMVV--PRSN----VRGVKY----EPLVTEHIWMKSWPDHGT-PE
|. ..|.. . . || |.|. |..| .|||| .. . |.| |. || | .| .. . . .||..| .|
qekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvre
VESFLRCMQA-VRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNP
|. .. . | | ||||||..|.|||.... .. . || |. .|. . .|.| || .||....
prtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmy
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 964-1152 | 4e-35 | 116.1 | In-house | 8-144 (152) | alignment | ||
Range on Protein: 964-1152
Range on HMM: 8-144/152.0
HRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPR---KCSPYFpqdpgasktfenftvtcqslvdaqvyerrrlmvvprsnvrgvkyeplvteHI
....||.|||.|.| .|||||.. . ..||.. .. || |. ..
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..................................................qy
WMKSWPDHGTPEVESFLRCMQAVRRD-FEEPSGRVVVHCSAGVGRSGTFIAFDMLAdaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQFIYE
|||||.|. . .|. . . . ....|.|.|||||||||.||..| ... . .... .| ..|..| ..|.. .|..|.||
lhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 919-1154 | 9.5e-35 | 114.6 | In-house | 32-265 (281) | alignment | ||
Range on Protein: 919-1154
Range on HMM: 32-265/281.0
KAARANPAKNRYSDILPYDASRVPLKQ--IGAAEGDYINANYMP-NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS---INPRKCSPYFPQDP
| ||||..| | ||| || ||| |||. . .| || .||| | |||||.. | . ..||| | ||. |||..
fnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprna
GASKTFENFTVTCQslvDAQVYerrRLMVVPRSNVRGVKYEPLVTEHIWmKSWPDHGTPEVESflrCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFD
. |....|. . |. | . .| | |. |.| .| | ||| || | . | | |.|||||||||||..| .
hcclqfdklsvsye...dstvn...kslvttrlnlsyegetrlithwlw.kewpdwqvpesse...vmlkilrkirarstppvihcsagvgrsgtlmave
MLADAIADGHSM-DVDAVVLQLRKH-RRIMVQTASQYQFIYEAL
. ..| .. |. .| .|| | ||| || .|.. |
ialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 952-1152 | 2.1e-34 | 114.1 | In-house | 3-164 (174) | alignment | ||
Range on Protein: 952-1152
Range on HMM: 3-164/174.0
DYINANYMP-NIGHRPYIAAQGPLPhteddFWRMVYGEHSPLVIMLCSINPR---KCSPYFPQdpgasktfenftvtcqslvdaqvyerrrlmvvprsnv
|||||... .. . .|| ||||. ||.|.. ... |.||.. ... || |.|
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.....................................
rGVKYEPLVTEHIWMKSWPDHGTPEVESFLRCMQAVRRDFEE-PSGRVVVHCSAGVGRSGTFIAFDMLADAIAdGHSMDVDAVVLQLRKHRRIMVQTASQ
... ... |||||.|... .|.....|.. ..| |.| |.|||||||||.||..| ... . .|. ..| .||..| |||| ||
.lredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQ
YQFIYE
|.|.|.
yrflyy
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 916-1154 | 1.2e-32 | 108.0 | In-house | 27-266 (285) | alignment | ||
Range on Protein: 916-1154
Range on HMM: 27-266/285.0
QTVKAARANPAKNRYSDILPYDASRVPLKQigaAEGDYINANYM--PNIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQ
| | ||| |||.|. . .|| ||. . ||| |..| | . ||..||||| | |||.|.| |. |.|||.. ||. |.|.
ctytayeanpdlnryadvrcieetrvvlkn...hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyype
DPGASKTFENFTVTCQSLVDAQVYeRRRLMVVPRSNVRGVKYEPLVTEHIWMKSWPDHGTPEVESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIA
| | .. .| . . | . | ||| .|. . |||. .|| . . . . ..|||||||||. ||.
klgevvkfgkyeitlteckeeaia.gtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvg
FDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
| . | . ... .| ..| | ||. |. |.| |
idyatirimenpniemldivremramrfqavqshmqflflyvvl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 921-1153 | 1.6e-32 | 107.6 | In-house | 5-236 (239) | alignment | ||
Range on Protein: 921-1153
Range on HMM: 5-236/239.0
ARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPNIGHR--PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDpgA
| | |||||..|. || ||| |... |||||.|. . |||.|| . . |||||.. |. ...|| . .|| |.|. .
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds..t
SKtFENFTVTCQSlvdAQVYERRRLMVVPRSNVrGVKYEPLVTEHiWMKSWPDHGTPEVES-FLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDM
|| . |. || . ..|. . . |.| | | | .. . |||.| |. . | . . .| . |.||||||||.|.|. |
sk.ycnlrvtlrk...tevfadyiirtfvmsqv.gqteeryvyqy.hftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvida
LADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEA
. ...|. | .|. | ||||. || ||. |
mlrqakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 921-1153 | 1.8e-32 | 107.4 | In-house | 4-235 (239) | alignment | ||
Range on Protein: 921-1153
Range on HMM: 4-235/239.0
ARANPAKNRYSDILPYDASRVPLKQIGA-AEGDYINANYMPNIGHR--PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDpgA
| | |||||..|. || ||| |... |||||.|. . |||.|| . . |||||.. |. ...|| . .|| |.|. .
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds..t
SKtFENFTVTCQSlvdAQVYERRRLMVVPRSNVrGVKYEPLVTEHiWMKSWPDHGTPEVES-FLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDM
|| . |. || . ..|. . . |.| | | | .. . |||.| |. . | . . .| . |.||||||||.|.|. |
sk.ycnlrvtlrk...tevfadyiirtfvmsqv.gqteeryvyqy.hftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvida
LADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEA
. ...|. | .|. | ||||. || ||. |
mlrqakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 925-1156 | 1.5e-31 | 104.4 | In-house | 48-342 (350) | alignment | ||
Range on Protein: 925-1156
Range on HMM: 48-342/350.0
PAKNRYSDILPYDASRVPLK---------QIGAAEGDYINANYMPN------IGHR-PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS---INPRKCS
|||||..||||. ||| || . |||||||. | |||.|.||| | |||..... . .....| | | .||
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
PYFPQDPGAS------KTFENFTVT-CQSLVDAQVYERRR--------LMVV---PRSNVRGVKYEPLVTEHIWMKSWPDHGT-PEVESFLRCMQ-----
|... . || . . || |.| . . ... .|.| .. .| |.| .. . ||.|. ..
rYWqegsydditvklaskwenimgindsslysadvkkeasdndnisddndlkdnnsltaitlaasdPyvvyqlqvknWkDlslllnPesilqalevkndl
---AVRRDF--EEPSGRVVVHCSAGVGRSGTFIAFDMLAD-----AIADGHSMD----------VDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. . . .. | ..||||||||| ||....|.| .| . .|..||| | |||. |. ||||||..
iddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallf
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 917-1151 | 2.5e-31 | 103.4 | In-house | 45-283 (310) | alignment | ||
Range on Protein: 917-1151
Range on HMM: 45-283/310.0
TVKAARANPAKNRYSDILPYDASRVPLKQIGAAEGDYINANYMP-NIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQdP
| .| . . ||||||.. |.||| || . .||| |||. | .| .|||| || |||||.. | . ...|| . || |.|
tyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywps.l
GASKTFENFTVTCQSLVdAQVYERRRLMV--VPRsNV----RGVKYEPLVTEHIWMKSWPDHGTPEVEsflrCMQAVRRDF-EEPSGRVVVHCSAGVGRS
| ..|. || | .. .| | | || || . . . | . | ||| | |. | .| . . | .|||||||..|
gvtetygcirvtnlses.seefeicnlavtfvpd.nvpvdeqpanlkelrvslikwpnwpdrgvpdek....chtvpqrllaqvrhgpcvvhcsagkdrl
GTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIY
.. .| .. | . |. .|.. |. .|.|.| | .|| || .|
yvvvalklkidkldrglkvdaeevktellksraiciqtelqyliid
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 919-1156 | 1.5e-30 | 100.9 | In-house | 50-287 (305) | alignment | ||
Range on Protein: 919-1156
Range on HMM: 50-287/305.0
KAARANPAKNRYSDILPYDASRVPLKQIGaaEGDYINANYM--PNIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS---INPRKCSPYFPQDPG
..| . .||||.|. | | | |.. ||| |||. | | .. .|.||||| .| |.|| || .. ..||| . ||. |.| |
qsadiaitknryqdvpcqdqsavkldkps..psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqg
ASKTFENFTVtCQSLVDAQVYERRRLMVVPRSNVRGVKYEPLVTEHIWMKSWPDHGTPEVE-SFLRCMQAVRRDfEEPsgrVVVHCSAGVGRSGTFIAFD
... . | . . .. || . . |. . . |. ||| | | . . | . |.| . | .|||||||.||.|| .| .
eklelksgiv.venvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgs.kvp...ivvhcsagigrtgtivaie
MLADAIADGHSM-DVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. . ||. .. . .| || .| .|. || ||. . |
yilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmln
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 917-1156 | 2e-30 | 100.6 | In-house | 42-285 (305) | alignment | ||
Range on Protein: 917-1156
Range on HMM: 42-285/305.0
TVKAARaNPAKNRYSDILPYDASRVPLkqIGAAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQDP
. | |. . |||| |. | || | |. .|| |||. . .| .| || .| ||| | . .. ..||| . .||. ||. .
afkeaq.eagknrykdvgcldnnrvkl..egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskd
GASKTFEN----FTVTCQSLVDAQVYERRRLMVVPR-SNVRGVKYEPLVTEHIWMKSWPDHGTPEVESFL-RCMQAVRrdfeEPSGRVVVHCSAGVGRSG
. .||. .| ..| | . . . | . | . . . | ||| | | . . .. | | .|||||||.||.|
kdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekar....pskgpivvhcsagigrtg
TFIAFDMLADAIADGHSMD-VDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. . .. . | . |. .. | .. ..|. | .|| || |... . |
svvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 915-1156 | 5.8e-30 | 99.3 | In-house | 34-269 (288) | alignment | ||
Range on Protein: 915-1156
Range on HMM: 34-269/288.0
RQTVKAARANPAKNRYSDILPYDASRVPLKqigAAEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQ
..... |||...|| .. |..|| |. ||.|| .. . | | || || | . .|.|. . ..||| . .| |||
idiidsfianptrdryenlprcditrvkls...ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPs
DPGASKTFENFtvtCQSlVDAQVYERRRLMVVPRSNVRGVKYEPLVTEHIWMKSWPDHGTPE-VESFLRCMQAVrRDFEEPsgrVVVHCSAGVGRSGTFI
| . . . |. | . . .|..| .. . |. . .. .. |.|.| || |.|| .. . .....| .|||.||||||.||.|
klGekarigrl...ctv.vkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.kslqkP...ivvhssaGvGrtgtli
AFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. .... . . .. .||..|. .|| || ... ...
lilialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvle
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 949-1154 | 7.3e-30 | 99.3 | In-house | 16-167 (178) | alignment | ||
Range on Protein: 949-1154
Range on HMM: 16-167/178.0
AEGDYINANYMPnigHRPYIAAQGPlphteDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQDPGasktfenftvtcqslvdaqvyerrrlmvvprs
.|||||... .. |.....| |...... .. ....|.. . || ||.|.. |
ersdyinaseil...pglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................................
nvrgvkyeplvTEHIWMkSWPDHGTPE-VESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAiadghSMDVDAVVLQLRKHRRiMVQTA
..... .||||.|. | ||........ .|. |.|.||||||||||||..| ... ........ ..|..|. .|..
...........iqylhi.pipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnp
SQYQFIYEAL
.|....||
gqlrqLyefe
|
|||||||||
PTPc_DSPc_SM00012 | 1058-1155 | 1.9e-29 | 97.3 | In-house | 3-104 (105) | alignment | |||
Range on Protein: 1058-1155
Range on HMM: 3-104/105.0
EHIWMKSWPDHGTPE-VESFLRCMQAVRRDFEEP--SGRVVVHCSAGVGRSGTFIAFDMLADAIADG-HSMDVDAVVLQLRKHRRIMVQTASQYQFIYEA
|.....|||||.|| ..|.|. ..||.. .. |. |||||||||||.|||.|.|.| . . .. ...|. .| .|||.|. |||| ||.|.|.|
khyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyra
LK
|.
ll
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 944-1148 | 7.6e-28 | 92.1 | In-house | 68-271 (301) | alignment | ||
Range on Protein: 944-1148
Range on HMM: 68-271/301.0
KQIGAAEGDYINANYMPNIGHR-PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDPGASKTFENFTVTC---QSLVDAQVYeR
. | . | ||..| || .||.||||. | .||| |. . ..||. . .||. |.|.... . . |... ..... ... .
evivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkis.k
RRLMVVPRSNvrgvKYEPLVTEHIWMKSWPDHGTPEVES-FLRCMQAVRrDFEEPsgrVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRK
|.| |. .. |... | ..|.|.|.|. |. |. . |.| .|||||||.||| .||. ..|| .. ... . .||.
rtlevedstg....kfatrtvthyqysewtdrgvPkshaelfdlmelvk.ksekP...ivvhcsaGiGrsvafigteylareveadptieltealkhlre
HRRIMVQTASQYQ
|| ||| ||
hrwngvqtnsqly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 952-1153 | 2.1e-27 | 91.0 | In-house | 4-148 (151) | alignment | ||
Range on Protein: 952-1153
Range on HMM: 4-148/151.0
DYINANYMPNIghrpYIAAQGPLPhtedDFWRMVYGEHSPLVIMLCSINPRKCSPYFPQDPGasktfenftvtcqslvdaqvyerrrlmvvprsnvrgvk
||||..|. . ... .|||. ||..... .. ...|.| .|. | . .. |
dyinfsyvtgg....lyrsggpla....dflellkelgiktivnlrseeergycpeylpelg......................................
yepLVTEHIWMKSWPDHGTPEV-ESFLRCMQAVRRdfeEPSGRVVVHCSAGVGRSGTFIAFDMLADAiadghsMDVDAVVLQLRKHRRIMVQTASQYQFI
. ||.. .|||.|.|. ...|. ...... ..| |.||||||.||.||..| .... ....... ..|..| .||. |..|.
...ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
YEA
. |
lfa
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 899-1111 | 8.7e-27 | 88.9 | In-house | 22-249 (418) | alignment | ||
Range on Protein: 899-1111
Range on HMM: 22-249/418.0
EVYMRLRQEDEDLGYARQTVKAARANPAKNRYSDILPYDASRVPLKQIGAAEG-DYINANYMPNIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLC
.. .| .| .| . . . | .||||..||| . .|| ||.| || |||||||. . .|..||||| | ||||||. .. ...||
kikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriivmls
--SINPR-KCSPYFPQDPGASK------TFENFTVTCQSLVDAQVYERRrlMVVPRsNVR-GVKYEPLVTEHIWMKSWPDHGTPEVES-FLRCMQAV--R
| | | || |.|.. | . | | ||. | .. | |.| .. | . . |||| |. | . .... |
resencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdper..eiitr.nirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnr
RDFEEPSG----RVVVHCSAGVGRSGTFIAF
.. || ..|||||||||.||| .
qnqiipssdrnvpiivhcsagvgrtgtfcta
|
|||||||||
subfamily_egg_pd | Subfamily egg | 919-1153 | 8.5e-25 | 82.1 | In-house | 35-265 (307) | alignment | ||
Range on Protein: 919-1153
Range on HMM: 35-265/307.0
KAARANPAKNRYSDILPYDASRVPLK-QIGAAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS-INPRKCSPYFPQDPGAS
|. | | | . | ||| |. . | .|.| ||.. .| || || | |||||||. |. . ..|| | .. .| |.|. . |
aasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkeserceyywpkaesds
KTF--ENFTVTCQSLVDAQvyerRRLMVVPRSNVRGVKYEPLVTEHiWMKSWPDHGtpEVESFLRCMQAVRrdfeEPSGRVVVHCSAGVGRSGTFIAFDM
. .. ... . .. |. | . .. | . | . || | . . .| | || .. .| . | |||.. || ...|..| ..
lvtvpGslrienlkvdska....dplfrvtklklvGgddeerfleh.wqgdvnnss..dvysplrvlrklr....nlskpvvvqdilGvskaatlvaiei
LADAIADGHS--MDVDAVVLQLRKHRRIMVQTASQYQFIYEA
. | | | ||..||. |... .| |.|
allsllrGpitkslvlravvflrlrrrlsvesvllylfvyrl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 920-1154 | 1.3e-24 | 81.7 | In-house | 29-255 (267) | alignment | ||
Range on Protein: 920-1154
Range on HMM: 29-255/267.0
AARANPAKNRYSDILPYDASRVPLKQigaAEGDYINANYMPNI-GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRKCSPYFPQDPGASKTF
| | ..||. | |||| .||.|.. | .|||| |. . .|. |.|| | ||. .. .. | ...| . . ..| | .| .
iaeknqernrlddnlpyddtrvilrt...keeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwPPkmgqakky
ENFTVTCQSLVDAQVYERRRLMVVPRSNvrGVKYeplVTEhIWMKSWPDHgTpEVESFLRCMQA--VRRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLAD
...|| . . |. | . . . . || . | | | . . .|. . . . ..|. . .||.||.||||||||. | .
qdltvehslekeendyqiitlelkfkne..sahn...vtl.yyykkwnin.t.nnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqle
AIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
. .|. ....|. | .|.| .| .|.| |
raktegvsdifdflrkirsqriglvdtkeryiyihell
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 920-1079 | 1.4e-24 | 81.5 | In-house | 27-189 (297) | alignment | ||
Range on Protein: 920-1079
Range on HMM: 27-189/297.0
AARANPA--KNRYSDILPYDASRVPLKQiGAAEGDYINANYM--PNIGHR-PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQD
.|. | . |||| ||| .| .|| |.. . .| |||||.|. |. . || ||||| | ||||..|. . ..|.. .. || ||.|.
sakrnsslrknryrdilatddtrvkllr.viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsv
PGASKTFENFTVTCQSLVDAQvYERRRLMVVpRSNVRgvkYEPLVTEHIWMKSWPDHGTP-EVESFLRC
. .. .. | | . . ..| | . . | | | |. |||||| | ..| |
vqerlkagdvvveflsstsde.fdrviltel.qliyr...sesrvvrhvqflswpdhGvpsdledlvrf
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1053-1154 | 7.4e-24 | 79.5 | In-house | 44-139 (145) | alignment | ||
Range on Protein: 1053-1154
Range on HMM: 44-139/145.0
EPLVTeHIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEEPsGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQFIY
|.|.. ... .|||||.|. | .|........ .|. |.|.|||||||||.||..| ... ...... .. ..|..|...|.. .|..|.|
erlgi.qylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgqlrfly
EAL
|..
efe
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 937-1151 | 1.2e-23 | 78.7 | In-house | 31-252 (290) | alignment | ||
Range on Protein: 937-1151
Range on HMM: 31-252/290.0
DASRVPLKQIGAA-EGDYINANYMPNIGHRPYIAAQGPLPHT-------EDDFWRMVYGEHSPLVIMLCSINPR-------KCSPYFPQDPGASKTFENF
|.||.||. | ||| ||.. |. | |. .. .|| |. |.. |.||| . . |. |.|. | . .|...
eatrvvLkgygkrfnddyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgl
TVTCQSLVDAQVYERRRLMVvprsnvRGVKYEPLVTEHIWMKSWPDHGTPEVE-SFLRCMQAVRrdfeEPSGRVVVHCSAGVGRSGTFIAFDMLADAIA-
|| |.| . . |.|.|.| . . |.. .| ..|.| . ..| . ..| .| |. |.||| |. || .. | .. ||
tvkCkskekeddvetRelvv......kfddeeeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQkiae
DGHSMDVDAVVLQLRKHRRIMVQTASQYQFIY
.|. . .|. .|||.| ....| .. |.
tsgsvkledvlkalrkqralaitsalelafvd
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1059-1152 | 1.4e-22 | 75.4 | In-house | 51-139 (144) | alignment | ||
Range on Protein: 1059-1152
Range on HMM: 51-139/144.0
HIWMKSWPDHGTPEV-ESFLRCMQAVRRDFEEPsGRVVVHCSAGVGRSGTFIAFDMLAdaiadGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYE
... .|||||.|. | .|........ ||. |.|.|||||||||.||..| ... . .... .. ..|..| ..|.. .|..|..|
qylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 928-1153 | 8.5e-22 | 72.2 | In-house | 47-271 (312) | alignment | ||
Range on Protein: 928-1153
Range on HMM: 47-271/312.0
NRYSDILPYDASRVPLkqiGAAEGDYINANYMpNIGHRPY--IAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSIN---PRKCSPYFPQDPGAsKTFENFT
||| .| .| | | | || ||.. .| .| ...|||| | ||... | .|.||.. ||. | . | .|.
nrypniqcwdrgrftl...agdenfyihanfv.kictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgf.vdledhr
VTCQSLVDAQVYERRRLMVVPR---SNVRGVKYEPLVTEHIWmKSWPDHGTPE-VESFLRCMQAVRRDFEePsgrVVVHCSAGVGRSGTFIAFDMLADAI
| .. . .. . . . | |. | . . | |||||| |. ... || . ||..| | |. ||||||||.||.. . . |.
vyteycteieiggkskdkithrvlkvvvkatgqesklnhyqw.aswpdhgmpdscdtalrllsavkkdkk.p...viahcsagvgrtgtlaliesmiaal
ADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEA
.| . . ||| | |.. || . .
rhprkqnvkdsfvllrkdrarsvrvfpqyvyalrc
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 919-1154 | 4.3e-19 | 63.0 | In-house | 46-281 (302) | alignment | ||
Range on Protein: 919-1154
Range on HMM: 46-281/302.0
KAARANPAKNRYSDILPYDASRVplkQIGAAEGDYINANY--MPNIGhRPYIAAQGPLPHTE---DDFWRMVYGEHSPLVIMLCSINPR--KCSPYFPQD
|| ..|..||. |. .|. .| ...|.. .|.|| .|... |. | || | .| ..|||||. |. | .| .. | .||.
kafkknlkknqsedvpildsnlv...kleaepdsyvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlselfpkk
PGASKTFENFTVTCQSlVDAQVYERRRLM--VVPRsnvrGVKyEPLVTEHIWMKSWPDHGTPE-VESFLRCMQAVRRDFEEPSGRVVVHCSAGVGRSGTF
|. |..... | . |. .. |. |.. |.| |. . .... .. |... |. . . . .. | .. . ..|. |.|| |.|
sgdykeygkmfvNnrk.VekaeeektryviEvlPe....gcs.nsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagaf
IAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.. . . . .|. . .| ..|. | .|....|| ..| ||
ltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyial
|
|||||||||
ETC_C1_NDUFA5 | ETC complex I subunit conserved region | 1232-1283 | 7.1e-17 | 47.3 | Pfam-A | 2-53 (57) | alignment | ||
Range on Protein: 1232-1283
Range on HMM: 2-53/57.0
NPQEVLSGLYGATLQVVGRMPQSAAYRSKVEAITKERQAILEKSEDVDAFEA
|| . | || ||... .|....|| .||.|||| .| |..||| . |
nPrsaLlalYtktLkkLkkiPedsvYRqstEaltkeRLkiveeeedvekiee
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 973-1151 | 7.2e-17 | 55.8 | In-house | 99-281 (302) | alignment | ||
Range on Protein: 973-1151
Range on HMM: 99-281/302.0
PLPHTEDDFWRMVYGEHSPLVIMLCSI---NPRKCSPYFPQDPGASKTFENFTVTCQSLVD--AQVYERR--RLMVVPRSNVRGVKYEPLVTEHIWMKSW
| | . .| .. . .|. |||. . .||..|. .. | .| ..||. |. . .. ... .| | | . | . . . .|
pkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsaw
PDHGTPEVESflRCMQAVRrDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIY
||||.|. .. .. | |.|||||||||.||..| . . . |. .|| .|. | ||...| ..
pdhGapkeay..taldilk.fcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyll
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 977-1149 | 2.2e-16 | 54.7 | In-house | 40-212 (255) | alignment | ||
Range on Protein: 977-1149
Range on HMM: 40-212/255.0
TEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQDPGASKTFENFTVTCQSLVDAQVYeRRRLMVvprSNVRGvKYEPLVTEHIWMKSWPDHGTPEV
| | |.... . |.||| . ||| ||| . . ... .||. . | | . .. |.. | . .| | |... .||
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvl.rtleit...stlge.kkkthtvkhysykGWieknaPel
ESFLRCMQAVRRDfeepSGRVVVHCSAGVGRSGTFIAFDMLAD----AIADGHSMDVD--AVVLQLRKHRRIMVQTASQYQF
.. . | || | ||||||.|.||| .|. ... .. . ..| .. .||..|. ..| | |
areilnilkvvrd....sksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlaf
|
|||||||||
subfamily_eak_pd | Subfamily eak | 916-1154 | 3.9e-16 | 53.4 | In-house | 43-301 (332) | alignment | ||
Range on Protein: 916-1154
Range on HMM: 43-301/332.0
QTVKAARANPAKNRYSDILPYDASRVPLKQIGAAEGDYINANYM--PNIGHRpYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS---INPRKCSPYFPQ
..|| . . .|.||| | | . |||| . ...|.. || . . ||.||. ..|| ...| . | |||.
sisetarleavnrnvvkivpydrylvrltssqlnrlGyinaslaefsevGrk.yiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpd
DPGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKY----------EPLVTEHIW-MKSWPDHGTPEVESF-LRCMQAVRRDFE--EPSGRVVV
. | . |.... | ...| | |.. . |.. | . . . | . |.. . ..... . . || ..
ktreelkfGildverkefvkrniletrllelskGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallsstlkkyihtppsfapii
HCSAGVGRSGTFIAFDMLADAIADG--HSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
.. | |.|.|. |.| | . . |. ..|. ...| | .| |. ||||..
qsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeiv
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 923-1155 | 4.3e-16 | 53.4 | In-house | 46-276 (303) | alignment | ||
Range on Protein: 923-1155
Range on HMM: 46-276/303.0
ANPAKNRYSDILPYDASRVPLkqigaAEGDYINANYMPNIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLC---SINPRKCSPYFPQDPGAsKTFE
| |||. |.. | |.| | .. || |.|. .. | .| ||.|| |||.|. .. |..| . ||.. ||
knmdknrfvdvicldhskvkl.....sdssyihasyleldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdf.lkfe
NFTVTCQSLVDAQVYERRRLMVVPRSNVrgvKYEPLVTEHIWmKSWP-----DHGTPEVESFLRCMQAVRRDFEEPSGRVVVhCSAGVGRSGTFIAFDML
. .. . .. . | |. || .| .. | . |.|| .|.|.. . .|.| | . . . | . .|.||.||| |.
ersirvgefkrvelgdgwvlkvlsvsng...dyksflhvhhy.kawphnsipsdgspkfvkqiwqlqsvlrkysdstptvym.slsgcgragtfalfeta
ADAI-ADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
.. .. |.|. .. ..|. | || ||. ..| |
hlslhseqasldlvkclenvrngrlhavqnlsqfsvvytlla
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 963-1152 | 1.2e-15 | 52.3 | In-house | 3-198 (199) | alignment | ||
Range on Protein: 963-1152
Range on HMM: 3-198/199.0
GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRKC---SPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYEplvTEH
|.| |||.| || .| |||.||. | ..|. . | . |.| .. . ...||..... | |... . | |
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstre...ish
IWMKSWPDHGTPEVESFLRCMQAV---RRDFE-EPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSM--DVDAVVLQLRKHRRIMVQTASQYQFIYE
. || .. ||.| |. . | . .| | |.|||| | | .| |.|.|. . . .. |. | .||. | .. . .|.|||.
yqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 963-1152 | 1.2e-15 | 52.2 | In-house | 2-197 (198) | alignment | ||
Range on Protein: 963-1152
Range on HMM: 2-197/198.0
GHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRKC---SPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMVVPRSNVRGVKYEplvTEH
|.| |||.| || .| |||.||. | ..|. . | . |.| .. . ...||..... | |... . | |
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstre...ish
IWMKSWPDHGTPEVESFLRCMQAV---RRDFE-EPSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSM--DVDAVVLQLRKHRRIMVQTASQYQFIYE
. || .. ||.| |. . | . .| | |.|||| | | .| |.|.|. . . .. |. | .||. | .. . .|.|||.
yqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1084-1154 | 1.8e-15 | 51.4 | In-house | 240-311 (319) | alignment | ||
Range on Protein: 1084-1154
Range on HMM: 240-311/319.0
RRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADAIADG-HSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
| .| | .||||| ||||.|. || |. . . .|.|. .| ..|. | |.| ||.||| |
rsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 926-1080 | 4.9e-15 | 50.0 | In-house | 30-186 (319) | alignment | ||
Range on Protein: 926-1080
Range on HMM: 30-186/319.0
AKNRYSDILPYDASRVPLKQIGAAEG-DYINANYM--PNIGHRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINP---RKCSPYFPQDPGAS--KT
|.|. ...| .|| |..|| . |..|.|. .. . ||||| .| . ||||.|. | .. |... ..|. |.| . ..
dksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntsl
FENFTVTCQSLVDAQVYERRRLMVvprSNVRGVKYEPLVteHIWMkSWPDHGTPEVESFLRCM
. .. || . . | |.. .| . . .| | | |.. . | |. | .|
yGdilvtlkgrevkdryaistlll...krvdkeesrelt..hywy.kwleaevPaeeaaliam
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 977-1149 | 4.4e-14 | 47.0 | In-house | 46-218 (263) | alignment | ||
Range on Protein: 977-1149
Range on HMM: 46-218/263.0
TEDDFWRMVYGEHSPLVIMLCSINPR---KCSPYFPQDPGASKTFENFTVTCQSLVDAQVYERRRLMvvprSNVRGvKYEPLVTEHIWMKSWPDHGTPEV
| | |.... . |.||| | ||| ||| . . ..| .|.. .. . . |. |.. | . .| | |... ||
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlell....stlge.KkkthtvkhysykgWiekndpel
-ESFLRCMQAVRRdfeepSGRVVVHCSAGVGRSGTFIAFDMLAD----AIADGHSMDVDA--VVLQLRKHRRIMVQTASQYQF
.. |. ....| | ..|||||.|.||| | ... .. . ..| .. .||..|. ..| | |
areilnilkvarn.....skslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLaf
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1059-1159 | 5.3e-14 | 46.4 | In-house | 93-195 (440) | alignment | ||
Range on Protein: 1059-1159
Range on HMM: 93-195/440.0
HIWMKSWPDHGTPEVE-SFLRCMQAVRRDFEE-PSGRVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKN
. ...|||.| |.. |. .| | |. .| ..||||||.||.| || | . .|. ... .|. | |||| || |..||. .
qyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavle
PLC
|
gll
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1093-1154 | 2e-12 | 41.6 | In-house | 230-291 (297) | alignment | ||
Range on Protein: 1093-1154
Range on HMM: 230-291/297.0
RVVVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEAL
..||||||||||| . |.... . .. || |.. .||. | .||| |....|.|
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydav
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1060-1155 | 3.8e-12 | 41.7 | In-house | 80-174 (194) | alignment | ||
Range on Protein: 1060-1155
Range on HMM: 80-174/194.0
IWMK--SWPDHG-TPEVESFLRCMQAVRRDFEE-PSGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALK
| .||.| .| | || ...| . ..| |.| |.||| ||.||.||..| .. . |.... . .| |. .... .... ... |
ieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyr.....lgmsaeeAialfrekRpgaipnqdyleallkryk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 925-998 | 6.9e-12 | 39.3 | In-house | 49-140 (349) | alignment | ||
Range on Protein: 925-998
Range on HMM: 49-140/349.0
PAKNRYSDILPYDASRVPLKQI---------------GAAEGDYINANYM--PNIG-HRPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCS
|||||.|||||. ||| ||. .. |||||||. ..| .. ||| | ||| | |||.... . .||. | .
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnd
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 923-1024 | 3.2e-11 | 37.3 | In-house | 95-194 (244) | alignment | ||
Range on Protein: 923-1024
Range on HMM: 95-194/244.0
ANPAKNRYSDILPYDASRVPLKQiGAAEGDYINANYMPNIGHR-PYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRkcSPYFPQDPGASKTFENF
| ||| . ||.| .|||| . |. |||| .. .| || .| || | |||.|. | ....| |.. |.|. |.
nnswknregaglpfdfnrvplsk.gsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee..deywpdseplewyeedi
TVT
|||
tvt
|
|||||||||
PTEN_1 | 1064-1151 | 8.6e-11 | 37.0 | In-house | 101-186 (196) | alignment | |||
Range on Protein: 1064-1151
Range on HMM: 101-186/196.0
SWPDHGTPEVESFLRCMQAVRRDFEE--PSGRVVVHCSAGVGRSGTFIAFDMLADAIadghsMDVDAVVLQLRKHR-RIMVQTASQYQFIY
...|||.| ..... . . . . |.||| ||.||||| .| ... ...| . .|..| .......|| ....
pieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk.....ltadeAlelvrekRppgapnspsqerlle
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1095-1158 | 1.1e-10 | 35.7 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 1095-1158
Range on HMM: 2-65/69.0
VVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPL
|||||.| ||.||||| . | .|. | .|| | .|| .| ||..|| . |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1095-1158 | 1.6e-10 | 35.1 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 1095-1158
Range on HMM: 1-64/69.0
VVHCSAGVGRSGTFIAFDMLADAIADGHSMDVDAVVLQLRKHRRIMVQTASQYQFIYEALKNPL
|||||.| ||.||||| . | .|. | .|| | .|| .| ||..|| . |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1063-1152 | 8.6e-09 | 30.1 | In-house | 88-170 (182) | alignment | ||
Range on Protein: 1063-1152
Range on HMM: 88-170/182.0
KSWPDHGTPEVESFLRCMQAVRRDFEEpsGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQFIYE
.|.|.|.. .|. | .. | .| |.| ||| || || | || .. .... . . .|..| .|| .| ... |
fgwkDygvasleriLdivkvvafalqe..gkvavhChaGlGrtGvliacylvya.....krltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 967-1025 | 1.3e-08 | 28.6 | In-house | 238-295 (440) | alignment | ||
Range on Protein: 967-1025
Range on HMM: 238-295/440.0
YIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRKCSPYFPQDpGASKTFENFTVTC
.||.| || | ||||.|. . .||| .| . || |.| . | || |||
fiatqmpldstvldfwrlvhdyristiimlnqlndktcsiywpvn.trsvtfgpftvgh
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1090-1155 | 5.1e-08 | 26.6 | In-house | 264-341 (349) | alignment | ||
Range on Protein: 1090-1155
Range on HMM: 264-341/349.0
PSGRVVVHCSAGVGRSGTFIAFDMLAD--AIADGHS-------MDVDA---VVLQLRKHRRIMVQTASQYQFIYEALK
. ..|||||| ||.|... .|.| . .| . | .| .||| | ||| .|. .|||||
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealL
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 914-972 | 5.4e-08 | 26.9 | In-house | 38-95 (95) | alignment | ||
Range on Protein: 914-972
Range on HMM: 38-95/95.0
ARQTVKAARANPAKNRYSDILPYDASRVPLKQigAAEGDYINANYMPNIGH-RPYIAAQG
| || .. || |||. .|.||||.|| | . ||||| .. ||||||
apytvgsseanipknrflnifpydatrvvltt..krdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 1051-1151 | 7.7e-08 | 27.5 | In-house | 72-173 (184) | alignment | ||
Range on Protein: 1051-1151
Range on HMM: 72-173/184.0
KYEPL-VTEHIWMKSWPDHGTPEVESFLRCMQAVRRDFEEPSGRV-VVHCSAGVGRSGTFIAFDMLADAIADgHSMDVDAVVLQLRKHRRIMVQTASQYQ
||. ..... . || .|..| . .... ... .|| . .| |||| || ||.|. |. .| . . .. .. .. . | . . |. ||
kydskkfdgrvavypfdDhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllksllle.kaeealelfaeaRtknkkgvtiPsqrR
FIY
...
Yve
|
|||||||||
PTPc_motif_SM00404 | 1075-1146 | 1.8e-07 | 26.2 | In-house | 65-130 (140) | alignment | |||
Range on Protein: 1075-1146
Range on HMM: 65-130/140.0
SFLRCMQAVrRDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQ
. .... . ...|. |.|.||| ||| ||.|.|.. .. ......... ... | |. ....
yldkvldfi.enaekkggkvlVHCqaGvSRSatliiaYlmry.....rqlslaeayefvkerRpiispnlnf
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 1067-1148 | 4.7e-07 | 24.7 | Pfam-A | 50-125 (133) | alignment | ||
Range on Protein: 1067-1148
Range on HMM: 50-125/133.0
DHGTPEVESFLRCMQAVRrDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQ
.. | .. . .... .. ..|. ..|.||| ||. ||.|.|. .. ...... . ... | .....|.. .
etetkiskeleeavefie.kaeqkgkkvlVHCqaGisRSatliiaYlmkt.....knlslneAyefvkerrskispnagflr
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 1067-1148 | 4.7e-07 | 24.7 | In-house | 50-125 (133) | alignment | ||
Range on Protein: 1067-1148
Range on HMM: 50-125/133.0
DHGTPEVESFLRCMQAVRrDFEEPSGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQ
.. | .. . .... .. ..|. ..|.||| ||. ||.|.|. .. ...... . ... | .....|.. .
etetkiskeleeavefie.kaeqkgkkvlVHCqaGisRSatliiaYlmkt.....knlslneAyefvkerrskispnagflr
|
|||||||||
subfamily_CDKN3_pd | Subfamily CDKN3 | 1064-1152 | 2.8e-06 | 21.0 | In-house | 106-190 (202) | alignment | ||
Range on Protein: 1064-1152
Range on HMM: 106-190/202.0
SWPDHGTPEVESFLRCMQAVRRDFEEPSGrVVVHCSAGVGRSGTFIAFD--MLADAIADGHSMDvdaVVLQLRKHRRImvQTASQYQFIYE
.| ..|.. | |. .. .| ... . .||| |.||| || .| | | ...| . .|. | | || ||... |
piadglvpdiasclkileelrinlkayrk.tlvhcygglgrsslviaclllylddtiepkdaid...klrdlkgsrai..qtvkqynylse
|
|||||||||
subfamily_PTPMT1_pd | Subfamily PTPMT1 | 1065-1149 | 4.2e-06 | 21.3 | In-house | 81-160 (171) | alignment | ||
Range on Protein: 1065-1149
Range on HMM: 81-160/171.0
WPDHG-TPEVESFLRCMQAVRRdFEEPSGRVVVHCSAGVGRSGTFIAFDMLADaiadgHSMDVDAVVLQLRKHRRIMVQTASQYQF
.|. .|..|. .. .. ... . . || ||| || |||.| .| .. . .. . . |.| |.|. |..
tvDfteapdleklekgvefiek.vaskgkrvYvHCkaGrgRsatlvacylmkk.....eklspeeAlkalkkkRkiirlakkqwka
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 924-1019 | 6.4e-06 | 19.9 | In-house | 34-132 (332) | alignment | ||
Range on Protein: 924-1019
Range on HMM: 34-132/332.0
NPAKNRYSDILPYDASRVPLKQIGaAEGDYINANYMPNIGHR-PYIAAQGPL-PHTEDDFWRMVYGEHSPLVIMLCSINPR--KCSPYFPQDPGASKTFE
| || . .| ||| | . |. ||... .. || || |. ||| ||||| . ..... |. . . .|| | | |.|
nmdmnriphlycfdhsrvelapqd.gkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrkapydisdrgfeksfl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 922-965 | 6.6e-06 | 19.7 | In-house | 45-89 (440) | alignment | ||
Range on Protein: 922-965
Range on HMM: 45-89/440.0
RANPAKNRYSDILPYDASRVPLKQI-GAAEGDYINANYMPNIGHR
| |||| .|| || ||| |... | . ||||| |. | |
pnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingiesr
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 934-1010 | 9.2e-06 | 20.0 | In-house | 3-71 (130) | alignment | ||
Range on Protein: 934-1010
Range on HMM: 3-71/130.0
LPYDASRVPlkqigaaEGDYINANYMPNIGH-RPYIAAQGPLPHTEDDFWRMVYGEHSPLVIMLCSINPRkcSPYFPQ
|... ||.. . .||||... .|. . |. .| || | |||.|. . ....| |.. |.|.
lefevsrlq.......gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee..deywpd
|