Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_PTPN23_pd | Subfamily PTPN23 | 831-1159 | 4e-136 | 447.5 | In-house | 2-288 (288) | alignment | ||
Range on Protein: 831-1159
Range on HMM: 2-288/288.0
TVAHLQQAYPDGKSGFDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTS
.|..||....|||...||.|..||.......|..|.|.|......||.|||||||..||... ||.||||||..|..|..|||||...|.|..||.
lveelqrkmldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr.....gskDDYinAsfvkdlspgcPdfiatqaPlqstl
GDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLRPDHTKMVRHVkqfHYTSWPDHGVP
.|||.||..|.|.||||... ||.|.||.|||||...||||.... |.||||..|||....||.|..|||..|..|.|.|. ..||||..|||
nDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgd......lsvtlksvretethvervlkletldadavksvshl...qltsWpelGvP
ASPETFLEFLLAVKQHHDAVQRQSQTagepqsPLVVHCSAGVGRTGTFCCVYGVVAALpYVGNGLPllaaresgaqrptresqggklDIMNIVSRMREDR
|||||.|.|| .|.....||||.|.| ||||||||||||||.|..||..|..| ..||||. ||...|||.||.|
asPetllqfldevesayeavqrkskt......PlvvhCsaGvgRtgvfalvyaavrel.ekgngll.....................diiqvvsrlreqR
RFMVQTVDQYKFCYLASLEAARRYNDKYG
|||||...|.||.| |.||||||..||.|
rfmvqekeqlkfsyeavleaarrvldkrG
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 829-1149 | 2.4e-82 | 271.9 | In-house | 8-284 (288) | alignment | ||
Range on Protein: 829-1149
Range on HMM: 8-284/288.0
SETVAHLQQAYPDGKSGFDKEFALLEMEDAAhnRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSlTSGCPDFVCAQGPKHS
.| . .... ...|..|. .|| | . ...|.|. . |...|||.||||||..||...||.| ...||||| ... |...|||...
eellklvlkllangltglleefeellsllpd..ltlsaallpenleknRysdilpydhsRVkLsvldg.vegsdYinAsyidg.ynlkrkfIatqgPlpn
TSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPArcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLR-PDHTKMVRHVKQFHYTSWPDH
| .|||.|| .|..|||||.|.|.|.|| ||..||| |... . . . |||..| . . .. | |.|. |. .| .. .|.|..||||.||||
tvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygd......itvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdh
GVPASPETFLEFLLAVKQHHDavqrqsqtagEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPyvgnglpllaaresgaqrptresQGGKLDIMNIVSRMR
||| ||| .|.|| .|.... ...| ||||||||||||||.... .. | ..|..|....| |.|
gvpdspellldflrlvrkala..........sgggpvvVHCsaGvgRtgtfialdllleqle.......................keggvdvleavkrlr
EDRRFMVQTVDQYKFCYLASLE
| | .||||..||.|.| | ||
eqRpgmvqtpeqyrfvyealle
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 836-1154 | 7e-81 | 267.2 | In-house | 36-302 (308) | alignment | ||
Range on Protein: 836-1154
Range on HMM: 36-302/308.0
QQayPDGKSGFDKEFALLEMEDAahNRDTSCAAAERNVDRNRYRDILPYDRTRVHMqvlpgyGSTDDYINACHVRSLT-SGCPDFVCAQGPKHSTSGDFW
.. .........|| | . ....|.|. ..|.|.|||.||||||..||.. ....||||| .|. . |...|||...| .|||
ek..aldlglleeefeellsvkp..lleysvallpenkdkNrykdilpydhsRVkl......degsdYInAsyvdgyssklprkfIatqgPlpntvedFw
KMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCG-ETVSHPetalglALDVTLKEERETGPWIERDLIVETLRPDHTkmvRHVKQFHYTSWPDHGVPASP
.|| .|..|||||.|.|.|.||.||..||| | ... . . |||..| . . .. | |... |. . . |.|..||||.||||||| ||
rmvweqnvrvIvmLtklvengrekcaqYwplelgggsleyg......kftvtllseevlddytvrtleltnlgdges...rtvthfhytnWpdhgvPpsp
ETFLEFLLAVKQHHdavqrqsqtagePQSPLVVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMREDRRFM
| .|.|| .|.... |..| ||||||||||||||.... .. | . .|..|. ..| ..|| | .|
eilldflelvrksl............pggpivVHCsaGvGRtGtfialdllleqlek.......................eggvdvfeavkklReqRpgm
VQTVDQYKFCYLASLEAARRY
|||..||.|.| | || ....
vqtpeqylflyralleylklk
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 845-1155 | 1.1e-80 | 266.4 | In-house | 1-278 (284) | alignment | ||
Range on Protein: 845-1155
Range on HMM: 1-278/284.0
GFDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTDDYINACHVRSLT----SGCPDFVCAQGPKHSTSGDFWKMVVQQ
|...|| | . . ..|.|... |...|||.||||||..||....|.| ...||||| .|. .. |...|||. .| .|||.|| .|
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
RSRVIVMVTNLEERGRPKCDRYWPARcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLrpDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFL
..|||||.|.|.|.|| ||..||| ||.. . . . |||..| . . .. | | .. | . |. .|.|..||||||||||||.||| .||||
nvrvIVmltelvengrekcaqYwple.gevltygd......ftvtllseevkddytvrtleltnl..gytgesrtvthfhytswpdhgvppspedllefl
LAVKQHHDAvqrqsqtaGEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVgnglpllaaresgaqrptresqgG---KLDIMNIVSRMREDRRFMVQTV
.|...... ....| ||||||||||||||.... . | . | ..|. ..|.|.|| | .||||.
rlvrellen........lpgggpivVHCsaGvgRtGtfialdllleqleke.......................glllgvdvleavkrlreqRpgmvqtl
DQYKFCYLASLEAARRYN
.||.|.| | ||......
eqyrfvyealleylklkl
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 832-1149 | 5.4e-76 | 251.6 | In-house | 15-302 (307) | alignment | ||
Range on Protein: 832-1149
Range on HMM: 15-302/307.0
VAHLQQAYPDGKSGFDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTDDYINACHVRSLT-------SGCPDFVCAQG
. .... .|...|. ||| | . .. ..|.|. . | |.|||.||||||.|||....|.| ...||||| .|| . |...||
lllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqg
PKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLrpDHTKMVRHVKQFHYTSW
|...| |||.|. .|...||||.|.|.|.||.||..||| ||.. . . . |||..| . . .. | | |. | | |...|.|..||||.|
PlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygn......ftvtllseehldgytvrtlevtdl..dgtgesrtvthfhytgw
PDHGVPASPETFLEFLLAVKQHHDAvqrqsqtaGEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVgnglpllaaresgaqrptresqgGK---LDIMN
|||||| |.|..|.|. .|...... ...| .|||||||||||||.. | . | . |. .|. .
pdhgvppsfeelldfieevrkalee........lpkggpvlVHCsaGvgRtGtfiaaylmlrqleke.......................gtlldvdlle
IVSRMREDRRFMVQTVDQYKFCYLASLE
.|...|| | .||. .||.|.| | ||
avkllreqRpgavqnpeqyrflyealle
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 840-1149 | 5.8e-75 | 247.6 | In-house | 8-270 (273) | alignment | ||
Range on Protein: 840-1149
Range on HMM: 8-270/273.0
PDGKSGFDKEFALLemEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMqvlpgYGSTDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDFWKMVVQ
..|.... .|| || . .. ..|.|. ..| |.|||.||||||..||.. ....||||| .| .. . |...|||. .| .|||.|| .
llgltllleefell..lslkplltysvallpenkdknrykdilpydhsrvkl.....gdggsdyinAsyv.dgynlkrkfiatqgPlpntvedfwrmvwe
QRSRVIVMVTNLEERGRPKCDRYWPARCGE-TVSHPEtalglaLDVTLKEERETGPWIERDLIVETLRPDHtkmVRHVKQFHYTSWPDHGVPASPETFLE
|..|||||.|.|.|.||.||..||| || .. . . . |||..| . . .. | |... | .. .|.|..||||.|||||||.|.| .||
qnvrviVmLtelvelgrekcaqYwpleggelsltygk......ftvtllseetkddytvrtleltnlgtge...srtvthfhytgwpdhgvppsleslle
FLLAVKQHHDAVQRQsqtagepqSPLVVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMREDRRFMVQTVD
|. .|.... |. .. .| ||||||||||||||.... .. | . .|..|. ..| ..|. | ||||..
fielvrkalealpsn........gpvvVHCsaGvgRtgtfialdllldqlek.......................eggvdvleavkllrsqRpgmvqtpe
QYKFCYLASLE
||.|.| | ||
qyrflyealle
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 829-1155 | 1.1e-74 | 246.9 | In-house | 17-293 (297) | alignment | ||
Range on Protein: 829-1155
Range on HMM: 17-293/297.0
SETVAHLQQAYPDGKSGFDKEFALLEMEDAahnrDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTDDYINACHVRSLTSGCPDFVCAQGPKHS
| ..|. ...|.....|| | |.|.|. . |.|.|||.||||||..||. ....|. .||||| .| ...|...||| ..
svldlllllekansktllllefeellslkp....dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpe
TSGDFWKMVVQQRSRVIVMVTNLEERGRpKCDRYWPARCGetvS--HpetalglaLDVTLKEERETGPWIERDLIVETlrpdhTKMVRHVKQFHYTSWPD
| .|||.|| .|...||||.|.|.|.|| ||..||| . | . . |||... . . .. | | |. .. .|.|..|.||.|||
tvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygd........ftvtllkvehldgytvrtlevtn.....ngesrtvthfqytgwpd
HGVPASPETFLEFLLAVKQHHDAVqrqsqtagEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPyvgnglpllaaresgaqrptresQGGKLDIMNIVSRM
|||| |.|..|||| .|.... . ... | .|||||||||||||.. | .. | .|..|. ..|...
hgvppslellleflelvrealael........pkggpvlVHCsaGvgRtGtfiaaylmleqle.......................keggvdvleavkel
REDRRFMVQTVDQYKFCYLASLEAARRYN
|| |. .||| .||.|.| | || .|..
reqRpgavqtpsqyrflydallellkrkl
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 834-1155 | 4e-74 | 245.0 | In-house | 8-280 (317) | alignment | ||
Range on Protein: 834-1155
Range on HMM: 8-280/317.0
HLQQAYPDGKSGFDKEFALLEMEDAAhnrDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDF
.|.. .. .. .. .|| | . ..|.|. . | |.|||.||||||..||....|.| .||||| .| . . .. |...|||. .| .||
alldllksdftalleefedllslkld...tysvaelpenkdknrypdilpydhsRVkLsplgg.dldsdYInAsyv.dgpnlkrkfIatqgPlpntvedF
WKMVVQQRSRVIVMVTNLEERGRPKCDRYWPArcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLrpdHTKMVRHVKQFHYTSWPDHGVPASP
|.|| .|...||||.|.|||.||.||..||| |||. . . . |||..| | . .. | | || | .. .|.|..||||.||||||| ||
wrmvweqgvtvivmLteleelgrekcaqYwpl..getltygd......ftvtllseeelagitlrtlevedl...gdsesrtvthfhytgWpdhgvppsp
ETFLEFLLAVKQHHdavqrqSqtagEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPyvgnglpllaaresgaqrptresQGGKLDIMNIVSRMREDRRFM
...|.|| ||... . .|..|..|||||||||||||...| .. | ..|..|. ..| ..|| |. .
dllldfleavreal......e....dpggpvlVHCsaGvgRtGtfiaaylmleqle.......................keggvdveeavkelreqRpga
VQTVDQYKFCYLASLEAARRYN
||| .||.|.| | || .|..
vqtpeqyrflydalleylkrkl
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 842-1155 | 4.3e-74 | 244.8 | In-house | 11-281 (297) | alignment | ||
Range on Protein: 842-1155
Range on HMM: 11-281/297.0
GKSGFDKEFALLemEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMqvlpgYGSTDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQR
..... ||| | . .. ..|.|. ..|...|||.||||||.|||.. .. .|||||..| .. . . |...|||...| .|||.|| .|.
flalllkefeel..lpllllgslsvallpenleknRykdilpydhtRVkl.....ddegsdYinAsyv.dgydlkrkfIatqgPlpntvedFWrmvweqn
SRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalglaLDVTLKEERE--TGPWIERDLIVETLrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEF
..||||.|.|.|.||.||..||| ||.. . . . |||... . . .. | | |. . .. .|.|..||||.||||||| ||...|.|
vtvIvmltelvelgrekcaqywpleegesltygd......ftvtllsvevvllddytlrtlevtdt...gngesrtvthfhytgwpdhgvpespaslldf
LLAVKQHHDAVqrqsqtagEPQSPLVVHCSAGVGRTGTFCCVYGVVaalpyvgnglpllaaresgaQRPTRESQGGKLDIMNIVSRMREDRRFMVQTVDQ
. .|...... ...| .|||||||||.|||.... .. |. .. |..|| ..| .|| | ..|||..|
ielvrkvlkll........psggpvlVHCsaGvgRsgtfiaadlml....................qqledklkeggvdileavkklReqRpgavqtleq
YKFCYLASLEAARRYN
|.|.| | || ....
yrflyeallellkkkl
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 830-1148 | 6e-72 | 237.7 | In-house | 6-274 (278) | alignment | ||
Range on Protein: 830-1148
Range on HMM: 6-274/278.0
ETVAHLQQAYPDGKSGFDKEFALLEMEDAahnRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVrSLTSGCPDFVCAQGPKHST
. . .|.. ....|... .|| | . ..|.|. . |.|.|||.||||||..||....|.| .||||| .| .. . ...|...||| ..|
dllkallelllnlktllllefeellsfkl...dtysiallpenkdknrykdilpydhsrvklsllgg.dldsdYinAsyv.dgynvprkfiatqgPlpet
SGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWParcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLRPDHTkmvRHVKQFHYTSWPDHGV
.|||.|| ......|||.|.|.|.||.||..||| |... . . . |||..| . . .. |.| |. |. . . |.| ..||..||||||
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp...ggsltygd......ftvtllkeehlddytvrtlevtnlgdges...rtvthyhylgwpdhgv
PASPETFLEFLLAVKQHHDavqrqsqtagEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMRED
| |....|.|| ||... . ...|..|||||||||||||...| .. | . .|..|. ..|...||
peslsllldflkavreale..........dsngpvlVHCsaGvgRTGtfialyllleqlek.......................eggvdleeavkelreq
RRFMVQTVDQYKFCYLASL
| .||| .||.|.| | |
Rpgavqtpsqyrflyeall
|
|||||||||
| DSPc_SM00195 | 846-1150 | 4.6e-71 | 234.6 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 846-1150
Range on HMM: 2-261/263.0
FDKEFALLEMEDAAHnrDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLtSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVI
...|| ||... . .|..|. ..|...|||..|||||.|||... .. ...||||| ... . .....|||. || |||.||.......|
lkeefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekk.egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkii
VMVTNLEERGRPKCDRYWPARCGETVSHPetalglALDVTLKEERETGpwieRDLIVETLRPDHTK--MVRHVKQFHYTSWPDHGVPASPETFLEFLLAV
||.|. ||.|. ||||||| |.. . . |.|.|. .. ...|..||. ... | |.|..|..||||||| |.. .||.| ||
vmlteeeengkekcdrywpeesggketfg......kisvklvevekkk....deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellrav
KQHHDAVqrqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVGNglpllaaresgaqrptresqggkLDIMNIVSRMREDRRFMVQTVDQYKFC
|.... ..|.||||||||||||||... .. | . .|| .||...|. | |||| .||.|.
kksksts..........sgpivVhCsaGvgRtgtfvtidiilskleeekk.......................vdifeivkelRkqRpgmvqtleqYlfi
YLASLEA
| | ||.
yeailey
|
|||||||||
| PTPc_SM00194 | 846-1150 | 4.6e-71 | 234.6 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 846-1150
Range on HMM: 2-261/263.0
FDKEFALLEMEDAAHnrDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLtSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVI
...|| ||... . .|..|. ..|...|||..|||||.|||... .. ...||||| ... . .....|||. || |||.||.......|
lkeefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekk.egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkii
VMVTNLEERGRPKCDRYWPARCGETVSHPetalglALDVTLKEERETGpwieRDLIVETLRPDHTK--MVRHVKQFHYTSWPDHGVPASPETFLEFLLAV
||.|. ||.|. ||||||| |.. . . |.|.|. .. ...|..||. ... | |.|..|..||||||| |.. .||.| ||
vmlteeeengkekcdrywpeesggketfg......kisvklvevekkk....deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellrav
KQHHDAVqrqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVGNglpllaaresgaqrptresqggkLDIMNIVSRMREDRRFMVQTVDQYKFC
|.... ..|.||||||||||||||... .. | . .|| .||...|. | |||| .||.|.
kksksts..........sgpivVhCsaGvgRtgtfvtidiilskleeekk.......................vdifeivkelRkqRpgmvqtleqYlfi
YLASLEA
| | ||.
yeailey
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 832-1081 | 8.4e-69 | 227.7 | In-house | 11-234 (564) | alignment | ||
Range on Protein: 832-1081
Range on HMM: 11-234/564.0
VAHLQQAYPDGKSGFDKEFALLEMEdaaHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLTsGCPDFVCAQGPKHSTSG
.|... ... |..|. .|.. .. .. |... | .||| .|..||..|| .. ..| . ||||| .. . . .. .|||...|
kehvaklkansdlkfeeeykkieeg...qqftweaankpaNkaKNRyanivaYdhsRVvLskvegd.egsDYINAsfidgyr.krkayIAtqgPlaetie
DFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcGeTVSHPEtalglaLDVTLKEERETGPWIERDLIVETLRpdhTKMVRHVKQFHYTSWPDHGVPA
|||.|| .|.|..|||.|.|||.|. ||..|||.. | | .. | | |||.|| | . |...... . .. .| |.|||.|||||||||
dFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetyge......ltVtleeeeeladyeirtfklkkkk...ssesreVrqFhFtsWPdhgvpe
SPETFLEFLLAVKQHHDavqrqsqtagEPQSPLVVHCSAGVGRTGTFCCV
|....|... |.... . . |.||||||||||||||. .
satslLdlirkvralne..........pdagPivVhCSaGVGRTGtfivi
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 863-1149 | 1.1e-66 | 220.2 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 863-1149
Range on HMM: 2-244/249.0
DTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRY
..|.| . |.|.|||.||||||..||....||| . .||||| .. ... ...|...||| ..| .|||.|. .....||||.|.|.|.|| ||..|
eysvallpenkdknrypdilpydhsrvklsilpg.lflsdyinAsyi.dgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqy
WPArcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVqrqsqtagEPQS
|| |... . . . |||... . . .. | | .. | .. .|.|....||.||||||| |.|..|.|. ||...... ....
wpl..ggsleygd......ftvtllsvevkddytvrtleltnl...ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel........pkgg
PLVVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLE
|..|||||||||||||.. | .. | . ...|. ..|. .|. |. .||. .||.|.| | ||
pvlVHCsaGvgRtGtfiaaylmleqlek.......................elgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 830-1148 | 8.4e-66 | 216.9 | In-house | 7-276 (288) | alignment | ||
Range on Protein: 830-1148
Range on HMM: 7-276/288.0
ETVAHLQQAYPDGKSGFDKEFALLemEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSgCPDFVCAQGPKHST
. ||. ... ....|| .|. | ...... . .| ..||||.||||| .||... |. ... ||||| .. . . ....||| .|
spvakvakksarnrtgfseeynsL..aalektksvtagrlavnakknRyrnilpyDekrvklkklee.eagaDYinasyidgekk.kkkyiatqgPladt
SGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVEtlrpdHTKMVRHVKQFHYTSWPDHGV
.|||..| .... |||.|.| |.|. ||..|||. .. . . . ..|||.|..|.. ...| |..| ..| ....|..|..||||||
vndfWelvyenktstivmltelveggktkCeeYWPda.dkpknyGs......vtvtlveskeledfvlrkllle.....kkkteleitqyqylaWpdhgv
PASPETFLEFLLAVKQHHDAVqrqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMRED
|.| . .||.| ||. ..| . |..||||||||||||| . .. |. ..|....|...|.
Peskapllellrqvkvanqad..........tgpiivhCsaGvGrtgtFialdalidavee.......................edyiDvagtvaklRkq
RRFMVQTVDQYKFCYLASL
| ..|||. || |.| . |
RallvqtlkqYefiyevll
|
|||||||||
| BRO1 | BRO1-like domain | 53-426 | 1.3e-65 | 209.9 | Pfam-A | 2-376 (377) | alignment | ||
Range on Protein: 53-426
Range on HMM: 2-376/377.0
FLAASVKTAQPCAIEDTLIKFISQTLEQPGEDYRVELQQLRNLRATLHTG-HVDQQYLANARLYAAQLHFAKSRFYagSTTPQLDFSWLDTF-TKSFVSS
... .| .... . . | ..|..| ... . |. .|..|..|| .. | . |.. |.. | |||.. ..|| . ...|.| |.| |.| ...
lislplKetkevdlskpLsdyIletygeesssyeddlaelnklRqaavtpssrdesglelllrYyaqLellekrfp..drslkveFtWydafdtgsplaq
HALAHEYGSVLFNIAGAAGRLASLEfagADSSDDTLKTCLQMQQLSVAAIMAVQQQeLGDTPSHDMHAAALDVLLHVYTAQSYQCSLYKALHSNMKATTI
..|| | |||||.| . ..|. . |||. ||. .. | . | .... . ..|| |.... |.|| ... || ..| | ||.....|...|
rslafEkasvlFnlaalysqiaasq...nrssdeglkaAvkyfqrAaGafeylken.flhapseDlspetlkvlvklmlAqAqecflekaildkkkdsli
ARIAIRVANEFDAAHKALYSIETNKDHPwHLWQLCVQLKSMHARGLAQFYQGQAANKASEWGEEVGRLRAARDVLQAAIETAKA-VKNAVDVAAIQHTLN
|..| ||.... |..|| . .|... | |. ||.|... . ||..||..|...... ||...||..| ..|. |...||. .. ... . .
aklaaqvadlYeealealqesptktgip.kewaklvqvKaeyfkAlahyyqalaleekkkyGeaiarLqeAlellkeaqklakkckskselledlkelke
LVTERLTKAETDNNTIFHETVPSDAALSEIVAADLFAFKPFEPD-----PSAVDILHRLMPLDVHLAISTFSEQKATLVRNV
..|.|..|| ||. | .| ||. . |..| .|.| |.. . |....| |..|| | | .||.||.|||.
rikekleeaekdNdfiyleevpdeveltsikkaklvkalpinellsltkekgedlfkklvPiavheaaslyseekaklvrde
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 864-1153 | 1.3e-65 | 216.9 | In-house | 25-274 (278) | alignment | ||
Range on Protein: 864-1153
Range on HMM: 25-274/278.0
TSCAAAERNVDRNRYRDILPYDRTRVHmqvlpgygstdDYINACHVRSLtsGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYW
..| . |.|.|||.||||||..||. ||||| .... . . |...|||. || |||.|. .....||||.|.|.|.|| ||..||
itpalylgnldknRykdilpydhsrVk...........dYINAsyidgy..p.kkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqyw
PArcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETL-RPDHTKMVRHVKQFHYTSWPDHGVPASP--ETFLEFLLAVKQHHDAVQRQSQTAGE-
| |... . . . |||..| ... .. |.|.|. | ... . |.|...||..||||||| .| |||.| ........... .
pe..ggsltygd......ftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslll
--PQSPLVVHCSAGVGRTGTFCCVYGVVAalpyvgnglpllaaresgaqrptrESqGGKLDIMNIVSRMREDRRF-MVQTVDQYKFCYLASLEAARR
.. | .||||||||||||....| . .|..|. ..|. .|. |.. .||. .||.|.| . || .|
ldsggpvlVHCsaGvgRtGtlvaaylmle........................ll.eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 828-1146 | 3.8e-65 | 214.9 | In-house | 9-292 (306) | alignment | ||
Range on Protein: 828-1146
Range on HMM: 9-292/306.0
LSETVAHLQQA-YPDGKSGFDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQvlPGYGSTDDYINACHVR-SLTSGCPDFVCAQGP
... | .|.. .|.|| .|| |. |.| . . . .| .| .|||. |||.| ||| .. . .||||| .. .... . .. .||
ieqrvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk..epsvpgsdyinanyikkevkgsdksyiatqgc
KHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVshpetaLGlALDVTLKEERETGPWIERDLIVETLrpDHTKMVRHVKQFHYTSWP
..| |||.||.|. ||||||.|. |||. || ||||. .. | . || .|... .| |.| |. .. | |.| |.|..|||
lettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee......yG.kisvtnvseksladYilRelsvskk..kkkkeerevfqyhfksWP
DHGVPASPETFLEFLLAVKQHHDAVQRQsqtagePQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVGNglpllaaresgaQRptresqggKLDIMNIVSR
|||||..|...|.|| |..... .... . |.|||||||.|||||| . .. . . |. . ..|| ..|
dhgvpkdpgavLdfledvnrkqeeleea......eagpivvhCsaGiGRtGtfiviDillkliekkgl............da........didiqklvks
MREDRRFMVQTVDQYKFCYLA
.|| | .||| .|||| | |
vreqrsglvqteqqykfvyka
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 841-1152 | 4.1e-65 | 214.5 | In-house | 5-278 (290) | alignment | ||
Range on Protein: 841-1152
Range on HMM: 5-278/290.0
DGKSGFDKEFALLEMEDAAHNRDT----SCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGsTDDYINACHVRSLTSGCpDFVCAQGPKHSTSGDFWKM
.|. | ||| | .. ... ... ... .|.|| .|||.|||||| .||... . .||||| ... .. . .. |||| | |||.|
egeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeee.gsdYinanfikgvegkl.eyiaaqgPLpktlddfWrm
VVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalglaLDVTLKEERetgpWIERDLIVETLRPDHTKMVRHVKQFHYTSWPDHGVPASPETF
. ... ...||. .. | |. ||.|||| . .|.. . | . |||.||. ... |... ||. .. | |.|.|||||.|||||||.|...
iweknveivvmaCrevelgkkkCerYWpeegeeelefge......fevtleeek....avdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksl
LEFLLAVKQHHDavqrqsqtagEPQSPLVVHCSAGVGRTgtfccvyGVVAALPYVGNGLpllaaresgaqrpTRESQGGKLDIMNIVSRMREDRRFMVQT
||.. .|..... . ..||||||||||||| |.. |. || . | .| .||. ..| ..|..| .|||
lelielvrelqe..........sedaPlvvhCsaGvGrt.......Gtiiaidyvrell.............kaekipeeldvfdlvlelrkqraalvqt
VDQYKFCYLASLEAAR
.||.. | | .| .
keqyelvykavaelvq
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 865-1148 | 5.6e-65 | 214.5 | In-house | 2-240 (245) | alignment | ||
Range on Protein: 865-1148
Range on HMM: 2-240/245.0
SCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWP
|.|. . |.|.|||.||||||.|||.... .| .|||||..| .. .| | ..||| ..| .|||.|. ......|||.|..||.||.||..|||
svallpenkdknrysdilpydhtrvklspdgg.dldsdyinasyv.dgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywp
ArcGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAvqrqsqtagEPQSPL
||.. . . . |||..| . .. | | |. | .. .|.| ..||..||||||| ..|..|.|| .|... . .. |.
l..gesltygd......ftvtllseehlddytvrtlevtnl...gddesrevihyhylpwpdhgvpdllellldflefvrkalae.........dsngpv
VVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
.|||||||||||||...| .. | . ..... ..| ..|. |. .||| .||.|.| | |
lVHCsaGvgRtGtfiaaylmleqlek.......................elgvsleeavkelrsqRpgavqtpsqyrflyeall
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 872-1148 | 6.8e-63 | 207.6 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 872-1148
Range on HMM: 1-234/235.0
NVDRNRYRDILPYDRTRVHMqvlPGYGSTDDYINACHVRSLTsGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETV
| ..|||.||||||.|||.. |.... ||||| .|.. . |...||| || .|||.||.|....||||.|.|||.|| ||..||| . .|..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
SHPETALGLAldvtLKEERETGPWIERDLIVETLRPDHtkMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHdavqrqsqtaGEPQSPLVVHCSAG
.. . . | ||.... .. |.| .. .. |.|||.|||.|||||||.||. .|... .|.... . ..|.|||||||
tygdikvelk....ekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkveksk..........eaksgpvvVhCsaG
VGRTGTFCCVYGVVAALPYvgnglpllaarE-SgaqrptresqggkLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
|||||||... .. | | . .|...||...|. |. |||...||.|.| | |
vgRtgtfvaldilleqlea...........eee.............vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 872-1148 | 6.8e-63 | 207.6 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 872-1148
Range on HMM: 1-234/235.0
NVDRNRYRDILPYDRTRVHMqvlPGYGSTDDYINACHVRSLTsGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETV
| ..|||.||||||.|||.. |.... ||||| .|.. . |...||| || .|||.||.|....||||.|.|||.|| ||..||| . .|..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
SHPETALGLAldvtLKEERETGPWIERDLIVETLRPDHtkMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHdavqrqsqtaGEPQSPLVVHCSAG
.. . . | ||.... .. |.| .. .. |.|||.|||.|||||||.||. .|... .|.... . ..|.|||||||
tygdikvelk....ekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkveksk..........eaksgpvvVhCsaG
VGRTGTFCCVYGVVAALPYvgnglpllaarE-SgaqrptresqggkLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
|||||||... .. | | . .|...||...|. |. |||...||.|.| | |
vgRtgtfvaldilleqlea...........eee.............vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 864-1147 | 3.4e-62 | 205.5 | In-house | 2-238 (243) | alignment | ||
Range on Protein: 864-1147
Range on HMM: 2-238/243.0
TSCAAAERNVDRNRYRDILPYDRTRVHMqvlpgyGStDDYINACHVRSLtsgcPDFVCAQGPKHSTSGD----FWKMVVQQRSRVIVMVTNLEERGRPKC
.|.| . |...|||.||||||..||. .. .||||| ... . | . . ||| .| | ||.|. .....||||.|.|.|.|| ||
fsiallpenlsknrysdilpydhsrvkl......eg.sdyinanliyvt....prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekc
DRYWParcGETVSHPetalglaLDVTLKEERETGPWIERDLIVETLRPDHTKmvRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVQrqSQTAGE
..||| ||.. .. . |||..|.... .. | | .| | .|. . |.| ..||..||||||| ||| .|.|| .|... ... | .|
aqywp...gevtygd.......ftvtllseehlddytvrtlllenldlddlt..rlvihyhylpwpdhgvPdspedlldfldevrefieell..sllald
PQSPLVVHCSAGVGRTGTFCCVYGVVAALpyvgnglpllaaresgaqrptresqggKLDIMNIVSRMREDRRF-MVQTVDQYKFCYLAS
...|..||||||||||||... | . | ..|. ..| ..|| | . .||| .||.|.| |
sggpvlVHCsaGvgRtGtliaaylmllll...........................gvdleeavkllreqRpgkavqtpsqyrflyeal
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 831-1083 | 1.2e-61 | 203.3 | In-house | 12-240 (293) | alignment | ||
Range on Protein: 831-1083
Range on HMM: 12-240/293.0
TVAHLQQAYPDGKSGFDKEFAllEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSgCPDFVCAQGPKHSTS
.|... | . .| .|. |... ... ...| ...| ..|||..||||| .||... | . |..||||| ... ..| .|. .||| ..|
feehvkkmkadsdlrfseeye..elkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkd.esgsDYinanyipgyns.prefiatqGPlpetv
GDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcgetvsHPETALGlALDVTLKEERETGPWIERDLIVETlrpdhTKMVRHVKQFHYTSWPDHGVP
|||.|| ...|..|||.|.| |.|. ||..|||| . ... | . |||..|.|. |. |.| .| .|. |.|.|.|.|||||||||
ddfWrmvwekkssiivmltqlvekgkvkCeeYWPad......eepvlyG.dikvtlvaeeeledwvirelkiek.....ekeerkvrqyhftsWpdhgvP
ASPETFLEFLLAVKQHHDavqRQSQtagepQSPLVVHCSAGVGRTGTFCCVYG
...|.|.|. .|..... .... ..|.|||||||||||||| ..
ektktlldfvrtvreaie...ktas.....krPivvhCsaGvGRtGtfialdr
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 829-1081 | 2.8e-60 | 199.1 | In-house | 4-240 (563) | alignment | ||
Range on Protein: 829-1081
Range on HMM: 4-240/563.0
SETVAHLQQAYPDGKSGFDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTDDYINACHVRSLTSGcPDFVCAQGPKHS
.| . |. . . ||. ||..|| |..| .... |.. . .. | .||| .|..|||.||... ||| .. ||||| .. . .|. .||| ..
kefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqks.kafiatqgplkd
TSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPArcgETVSHPEtalglALDVTLKEERETGPWIERDLIVETLRPDHTKM---VRHVKQFHYTSWP
| |||.|. .|.. .|||.|||.|||| |||.|||. ... . . || |||.|| . .| |... |. ...| ...|.|.|||.||
tfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk...desetyg.....alqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWP
DHGVPASPETFLEFllaVKQHhdavqrqSQTAGEPQSPLVVHCSAGVGRTGTFCCV
||||| .. | | ||.. |.. . |.|||||||||||||.. .
dhgvPehslpvLif...vkks.......saankaeaGPivvHcsaGvgrtGtyivl
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 860-1150 | 3.4e-60 | 198.6 | In-house | 25-268 (273) | alignment | ||
Range on Protein: 860-1150
Range on HMM: 25-268/273.0
HNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGygstddYINACHVRSLT-SGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPK
... . ..| |.||||..||||.|||... | |||| ... ... .||| | |||.|| .|...||.|||. |.|. |
pldtcevgkkkenkdknryrnvlPydetrvklgdegg......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk
CDRYWPARCGETVShpetaLGLALDVTLKEERETGPWIERDLIVETLrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDavQrqsqtag
|.|||| . .... . |.|.| . . . |.| |. . ... .|.| ......|||||||.|.. .|.|. |.. .. .
chrywPesknkklk.....vsnrlevellkvqkldgfvvralavkds...esgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..d.......
epQSPLVVHCSAGVGRTGTFCCVYGVvaalpyvgngLPLLAaRESgaqrptresqggKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEA
..|.|||||||.||.||. ... | | |.. |. ..|. .|| ..|| |. .||| ||| |.| | ||.
..agPivvhcsaGiGrsGtlitidvv..........lglie.rdk............efdvkeivrklreqrqgvvqtkdqyifvykailev
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 861-1146 | 8.6e-59 | 193.7 | In-house | 30-270 (280) | alignment | ||
Range on Protein: 861-1146
Range on HMM: 30-270/280.0
NRDTSCAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSG---CPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRP
....|.| .|...|||||||||| |||... |. ||||| .| . .. .||| ..|. |||.|| .|.|..|||.|.| ||||
glaisaarkpenlsknryrdilpydatrvklk.....esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrv
KCDRYWPArCGETVshpetALGlALDVTLKEERETGPWIERDLIVETlrpDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHdavqrqsqta
|| .||| .... .| ..|....|.|| .. |.|... .|| |.. |. |..||||||| ... ||||. |.. .
kChqyWPe.tedel.....eyg.efsvkcekedetksyvlrelvlkd...ketkeerkilqlqylaWpdhgvPddsadflefvervrklr..........
GEPQSPLVVHCSAGVGRTGTFCCVYGVvaalpyvgngLPLLAAREsgaqrptresqggKLDIMNIVSRMREDRRFMVQTVDQYKFCYLA
..|.|||||||.|||| . . | |. |.| .. ...||..||. | .|||..|||| |
sgkeePvvvhCsaGigrtGvlilleta..........lalieaae.............pvypldivrtmrdqramlvqtasqykfvCea
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 823-1082 | 1.1e-58 | 193.8 | In-house | 2-234 (318) | alignment | ||
Range on Protein: 823-1082
Range on HMM: 2-234/318.0
VAIRALSETVAHLQQaypDGKSGFDKEFALLEMEDAAHNRDTScaAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLTSGcPDFVCA
. ...| . |..|.. .|. ...|. |. ... . | . | .||| .||.||.|||..| | | . ||||| .. .. .. |
isvedleshvrrlre...sGelllseeyerlsrseetvtslks..lepvnkaknryanilaydhtrvkLqmlege.egsDyinanyidGyrrk.kayiaa
QGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVShpetalglALDVTLKEERETGPWIERDLIVETlrpDHTKMVRHVKQFHYT
|.| | |||.|| .| |.||||.|..||||. |..|||| . .. .| |.|||| |.. .. | . |. .... .|.|.|.|||
qaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsyg........klvvelkeevelsdyvlrefkvtr...teeeesrqvrqyhyt
SWPDHGVPASPETFLEFLLAVKQhhdaVQRQSQtagepQSPLVVHCSAGVGRTGTFCCVY
||||.|||.|. ..|... |.. .|..|. ..|.||||||||||||.|. |
sWpdegvpesgaslldlvrqvsk....aqqksg.....agpivvhCsaGvGrtGvfiavd
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 838-1083 | 1.1e-56 | 187.2 | In-house | 16-241 (307) | alignment | ||
Range on Protein: 838-1083
Range on HMM: 16-241/307.0
AYPDGKSGFDKEFALLEMEdaAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTdDYINACHVRSLTSgCPDFVCAQGPKHSTSGDFWKMV
| . |. ||. || . ...|. .. . | .||| || ..|.||| .....| .. ||||| .... .|..||.| .| ||||.|.
rkrdtdfglakeyekLear..eidkstkvsekkenalknRyedikafDktRvkLkkingkeds.dYinasfikgyke.kkkfiaaqdPveatigDfWRmi
VQQRSRVIVMVTNLEERGRPKCDRYWPARcgetvshP----EtalglALDVTLKEERETGPWIERDLIVETLRPDH--TKMVRHVKQFHYTSWPDHGVPA
.| . .|||..||.| | ||..||| . . |.| .|.... .|.|.| | . . . |.| |.|||.|.| ||
aeqevtlivmlsnlteknrkkcakYWpie.......devqyg.....dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPe
SPETFLEFLLAVKQHHDAVqrqsqtagepQSPLVVHCSAGVGRTGTFCCVYG
.... |... |.... .||.||||||||||.|.| ..
vargllklieqvrelykln..........rsPivvhCsaGvgrsgifvalds
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 863-1148 | 8.2e-56 | 184.1 | In-house | 19-265 (274) | alignment | ||
Range on Protein: 863-1148
Range on HMM: 19-265/274.0
DTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRY
|. .. .|||..||| ...|| .. . . .|||| ... .| .||| .| |||.|. |....||||.|.|.|. . || .|
dqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavy
WPARCGETVSHPETALGlaldVTLKEERETGPWIERDLIVEtlrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVkqhhdavQRQSQTAGEPQS
.| . . .|. . . .. .. |. . | |... ... |.|| . ||.|||| .| ...|.|...| | ... ... .. .
fPdaedyeiserygdve....ikvekiverndysvrklvlk.....ylerersvkhywytdWPdhksPddantlldlvlev.......eesreeenakla
PLVVHCSAGVGRTGTFCCVYGVVAALPYvgnglpllaaresgaqrptresqGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
| |||||||.|||| | . | | ...|...||. .| || |||| .||.. . |
pvvvhCsaGiGrtGcfiaisiavrqlre.......................eivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 823-1082 | 1e-54 | 180.8 | In-house | 5-237 (319) | alignment | ||
Range on Protein: 823-1082
Range on HMM: 5-237/319.0
VAIRALSETVAHLQQaypDGKSGFDKEFALLEMEDAAhnrDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTdDYINACHVRSLTSGcPDFVCA
. .. | | . .|.. |. ...||| ||.. .. ... | |.| ..|||..||.|||||| .. |.| .. ||||| .. . |. .
ievqeLkerlkalas...tgetllekefkllkeavnd...tfdsaskeenkkknryqnilaydrtrvvlseldgvegs.dyinasfidgyqer.ekfiat
QGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVshpetalGlALDVTLKEERETGPWIERDLIVETLRPDHTKmvRHVKQFHYT
|.|.. | |||.|| ...| ..||.|.| |... |. .||| . |. | | |||.||.|. .| |.| .... . |.||.|.||
qaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeey.......G.rlivtleeeeeledyiirklklnkkssevet..Revkhfqyt
SWPDHGVPASPETFLEFLLAVKQhhdAVQRQSqtagepQSPLVVHCSAGVGRTGTFCCVY
.||||.|| . . |..| ... ...... . |.||||||||||||||. .
eWpdhdvPekatslldllkrirk...srektq......sgPivvhCsaGvGRtGtfivld
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 841-1086 | 1.2e-54 | 180.4 | In-house | 29-253 (330) | alignment | ||
Range on Protein: 841-1086
Range on HMM: 29-253/330.0
DGKSGFDKEFALLEmedAAHNR-DTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTdDYINACHVRSLTSgCPDFVCAQGPKHSTSGDFWKMVVQ
| | .|| | |.. . |. | | ..||. .||||| .||...|. | .. ||||| .. |. |||||. | |||.|. .
ddnklfreefnalP...agpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvees.dyinasfidGyke.kdkfiaaqGPkeetvedfwrmiwe
QRSRVIVMVTNLEERGRPKCDRYWPARCgeTVSHPEtalglaLDVTLKEERETGPWIERDLIVEtLRPDHT--KMVRHVKQFHYTSWPDHGVPASPETFL
|.| |||.|.|.|| . || .||| .|.. . . |....| .. . |...|. ||.| | .| |.|||.||||| |||. | |
qksativmltelkerkeekcaqywPdeG..lvtyGn......irvevedetvlvdytvrkflvq.qlpdatrekksrlvrqfhftswPdvGvPfepiGml
EFLLAVKQhhdavqRQSQTAGepqsPLVVHCSAGVGRTGTFCCVYGVVA
..| .||. . |.|| |.||||||||||||||. . |..
kllkkvkk......lnqqsag....pivvhcsaGvGrtGtfivldavle
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 833-1082 | 4.1e-54 | 178.6 | In-house | 4-229 (281) | alignment | ||
Range on Protein: 833-1082
Range on HMM: 4-229/281.0
AHLQQAYPDGKSGFDKEFALLEmeDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTdDYINACHVRSLTsGCPDFVCAQGPKHSTSGD
.||.| . ..|| .|.. |. .. . .. . |. || .|||..| || |||... .| ||||| .| ... | ... .||| .. .
khlkqlsqndnaGfieeyekla..aigvdntataskadenvlknrYsnivaYDatrvkvtpneenknt.DYinanfvpgyk.gekeyiatqgPvPaslva
FWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGetvshpETALGlALDVTLKEERETGPWIERDLIVETlrpdHTKMVRHVKQFHYTSWPDHGVPAS
||.||..|. ..|||||. | |. || |||| |. .| . |. ..|.|. .||| . .|. .. |.|.|..||.||||||||.
fWqmvweqkvsaivmvtreieagklkChrYWPddns......elkyg.dvtvkstaeeekatyierkfkler....esgetreveqlaytaWPdhGvPat
PETFLEFLLAVKQHHDAVQRqsqtagepqSPLVVHCSAGVGRTGTFCCVY
.. .||| .|.. .. . |||.|||||||||||. .
tkellefrkevlkltekktk.........aplvihCsaGvGrtGtyialD
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 833-1085 | 3.6e-53 | 175.8 | In-house | 15-247 (298) | alignment | ||
Range on Protein: 833-1085
Range on HMM: 15-247/298.0
AHLQQAYP-DGKSGFDKEFALLEMEDA-AHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLtSGCPDFVCAQGPKHSTS
.|.. . . .|...|| |. .. .. | ...| ..||| ||...| .|| .. . ||||| .. . .| . |. .|.| ..|
qklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekeda.deesdYiNAsflhay.kgrnafiatqaPltetv
GDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHpetalglaLDVTLKEERETGPWIERDLIVETLRPDhtkMVRHVKQFHYTSWPDHGVP
|||.||... . .|||.||||| .. |. .||| . || . ..|.|... | . | | |.|. . . |.|.|.|.|||||.|||
edFWrmvteedigtiVmltnleeldktkyhkywPdegketyge........itvsllskeefadlivrklkvskkkee...kerevrqlhftsWpdkgvp
ASPETFLEFLlavkqhhDAVQRQSQTAGepQSPLVVHCSAGVGRTGTFCCVYGVV
. .. |..| . |... | || ..|..|.|||||||.|||. .. |.
enatsvldll.......rkvrasqqqag..nkpvivqCsaGvgRsGtfiaidsvl
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 826-1081 | 1.2e-51 | 170.7 | In-house | 4-236 (305) | alignment | ||
Range on Protein: 826-1081
Range on HMM: 4-236/305.0
RALSETVAHLQQAYPDGKSGFDKEFALLEMEdaAHNRDTSCaaAERNVDRNRYRDILPYDRTRVHMQVLPGYGsTDDYINACHVRSLTSgCPDFVCAQGP
||... |....| . ..|..... .| .| . | . | |. .||...| ..| |.... . . |||||..| . . .. ||||
ialddlaayikearvysdkgleaqykslyee..eesidvgk..keankaknrlkeitlldddriiltekesld.dsdyinasyvdgykr.kkkyivaqgP
KHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPETalglalDVTLKEERETGPWIERDLIVETLRPdhTKMVRHVKQFHYTSWP
..| |||...|. . ..|||.|.| | |. || .||| . .|.. . |. |.||.|... .|||.| . . . | | | |.. |.||
lkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgef......svelksektasdyieRklkisiede..dkesrtvlqyqltdWP
DHGVPASPETFLEFLLAVKQHHDAVQrqsqtagepQSPLVVHCSAGVGRTGTFCCV
||||| .. ..|... |.... . . ||.|||||||||||.|..|
dhGvpqfatsllslikrvqkdqkkdk.........gvpllVhCsagvgRtGvfiav
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 841-1088 | 8e-51 | 167.8 | In-house | 13-250 (297) | alignment | ||
Range on Protein: 841-1088
Range on HMM: 13-250/297.0
DGKSGFDKEFALLEMEDAAhnRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTdDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQ
||.| ||.| . | .. .. |. .||| |.| ||.|||... ... . ||||| .| |. .||| . |. |||.|| .|
kgkrGlskeyaeirnepve..Gtflasklranleknrytdvlcydetrvvlakvdedeas.dyinanfvdGykqk.kafiatqGplkktvsdfWrmvWeq
RSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalglaLDVTLKEERETGPWIERDLIVETLRpdhTKMVRHVKQFHYTSWPDHGVPASPETFLEFL
. .||||.| ..|||| || .||| ... .. . | |. | .|. . .| | .. . |. |.| | ..||||.||| | ...|..|
evlvivmttrvvergrlkcgqyWpleeessaefgd......lsvsnveveeeedykvrvleiknvk...teesrkvthfqflsWPdyGvPssaaslldvl
LAVKQHHDAVQR--QSQTAGEPQ-SPLVVHCSAGVGRTGTFCCVYGVVAAL
.|... .. . ....|.|. |.|||||||.||||||. . .. |
ekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrl
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 853-1087 | 1.1e-49 | 163.7 | In-house | 13-227 (290) | alignment | ||
Range on Protein: 853-1087
Range on HMM: 13-227/290.0
LEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVlpgygSTDDYINACHVRsLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLE
|.... |.. .|. | ..| ..|||||. ||| .|.... . ||||| | | .. .||| .| . ||.|| .|.|. .||. ..
ldirkeasdfptreaklpenrnlnryrdvspydhsrikler.....adndyinaslve.leeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvv
ERGRPKCDRYWPARCGetvsHPETALG-LALDVTLKEERETGPWIERDLIVETLRpdhTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVkqhhdavq
|... || .||| . | | | |.| .| .. .. | | .| |. |. |.. .||||.||| ||| || .||.|| |
ekeqikcaqywPqgee....ekellledtklkvkliseerksyytvrllelenlk...tqetreilhfhyttwpdfgvpespaaflkflfkv........
RQSQTAGEPQSPLVVHCSAGVGRTGTFCCVYGVVAA
|.| . . . | |.|||||.||.|||| | ...
resGslssdvGpavihcsaGiGrsGtfclvdtclvl
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 863-1082 | 1.3e-48 | 160.3 | In-house | 11-218 (270) | alignment | ||
Range on Protein: 863-1082
Range on HMM: 11-218/270.0
DTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRY
... .| |. |||.|||| .||| .. | |. |||| .|| .. ...|.||. .| .||.|....... |||.|.|||.|| ||.||
esdlpeaargkklnRyadiLPsPatRvrleelee.dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerY
WPARCGETVSHPETALGLaldVTLKEERETGpWIERDLIVEtlrpDHTKMVRHVkQFHYTSWPDHGVPASPETFLEFLLAVKQHHDaVQRQSQTAGEPQs
|||. .|.|. . . ..|.||.|.| .| . | .| .. . | | |.|..||||||| .... |. .| .. |.|... . .
Wpaepkekvkledgkikv...lalseekeeg.yiltrlrle....ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlra.vrrsekeldkae.
PLVVHCSAGVGRTGTFCCVY
||.||||||||||||. .
PllvHcsaGvgRtGtlialD
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 858-1078 | 1.5e-47 | 157.0 | In-house | 35-246 (300) | alignment | ||
Range on Protein: 858-1078
Range on HMM: 35-246/300.0
AAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQvlPGYGSTDDYINACHVRSLTS-GCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGR
.. ..|.|. . |...||..|.|||. .||... | ....|||| ... . ... |||| . | |||.|| .| ..|||.|. || |.
kredallstaklpenaeknrfkdvlPyednrvels..ptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgk
PKCDRYWPArCGEtvSHPETALGlALDVTLKEERETGPWIERDLIVETLRpdhTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVQRQSQT
|. .|.| ... .. . | || | .... | . | .. | .| | | . || ||||||| ...||..| |. ........
eksfkyfPk.les..kkktvefg.kfkvttkfsedsdsvittglklkhlp...skeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves
aGEPQSPLVVHCSAGVGRTGTF
| . |..|||||||||||
.keskPPvlvhCsaGvGrtGvl
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 828-1086 | 1.7e-46 | 153.9 | In-house | 7-246 (325) | alignment | ||
Range on Protein: 828-1086
Range on HMM: 7-246/325.0
LSETVAHLQQAYPDGKSGFDKEFALLEMEDAAHnrdTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTdDYINACHVRSLtSGCPDFVCAQGPKH
. . | |... . . || .|| || .|. |. |...||.......|..|| .. . .|. ||||| ..|. . |. || |.
vvnlvehvekkkaqdqdgfahefgllpsddgia...kkvamkpenkaknrfknvvaldksrvvletkkddpss.dyinasylrdd.kkkdvflaaqaPlt
STSGDFWKMVVQQRSRVIVMVTNLEeRGRPKCDRYWPARCGETVSHpetalGlALDVTLKEERETGPWIERDLIVETLRPDHTkmvRHVKQFHYTSWPDH
.| .|.|..|.. |. |.|.. |. | .| ||| . |... | .|.| |. | .. | | | . .| | ||||.. ||.|
atindlWrlvldWrcsvvvvlneld.lgkdrcavywpkemgksktf.....G.glevklrtieeisdyvhrvldvkqvkkGet...rsvkqfqlqswddm
GVPASPETFLEFLLAVKQHHDAVQRQSQTAGepqsPLVVHCSAGVGRTGTFCCVYGVVA
||. | |.. .| ||. .. |. ...... |..|||||||||||.| ..| ..|
Gvqkrpatlisilqlvkavservtantkast....pilvhcsaGvGrtGvfislysala
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 845-1085 | 4.9e-46 | 152.0 | In-house | 23-234 (314) | alignment | ||
Range on Protein: 845-1085
Range on HMM: 23-234/314.0
GFDKEFALLEMEdaahnrdTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGStDDYINACHVRSLTSgCPDFVCAQGPKHSTSGDFWKMVVQQRSRV
|| .|. | .| . | ..||. |||.|||.|| .... | | ||||| . | . |. .|||...| |||..| ....
gfkeeyeslfeg.......wdaakkdenreknrsgdilaydrsrvflitidgdps.sdyinaalidsykr.paafivtqgPlqetvkdfWrlvydencas
IVMVTNLEERGRPKCDRYWPArcgETVSHPEtalglaLDVTLKEERETGPWIERDLIVET-LRPDHtkMVRHVKQFHYTSWPDHGVPASPETFLEFLLAV
|||.|.| | || || .||| .| . . ..|.| | . | . || |. . .| |.||....||||.|| | ...|... |
ivmltelvevgrvkClkyWPe...dtevygd......ikvelvetellaelvvrifrveklargqe..eirevrqfqflgWpdhdvPvsatgllklvrrv
KQHHDAvqrqsqtagePQSPLVVHCSAGVGRTGTFCCVYGVV
|.... . ..||||||| ||||||. . |.
kksqee..........eaGrivvhCsaGaGrtGtfiaidivl
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 866-1087 | 1.5e-45 | 150.2 | In-house | 37-235 (515) | alignment | ||
Range on Protein: 866-1087
Range on HMM: 37-235/515.0
CAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPA
| | | .|||..|||||..|| ..|. ||.|| ...|. . ....|||.... |||..|.|.. |.|||.|.| . || .|||
vaqeeinfkknryknilPydsvrvklevind.nPhsdyfnasyipsfdnd.kayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPd
RCGETVSHPETALGLaldvtLKEERETGpWIERDLIVetLRPDHtkmVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVqrqsqtagepQSPLV
. |..| . . | . | || | | | | |. |. .| | |||.| |||.||| ..| .. .|| |. . . ||.
kpgdsvkfGsikvel.....vsleactg.gikrkltv..lkgdd...srtvtqfhfteWPdkGvpkhtssllklikevkadhgqy..........thpli
VHCSAGVGRTGTFCCVYGVVAA
.|||||||||| .. . |||
ihcsaGvGrtGvvisidsvvah
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 866-1086 | 3.9e-45 | 149.0 | In-house | 3-200 (250) | alignment | ||
Range on Protein: 866-1086
Range on HMM: 3-200/250.0
CAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPkCDRYWPA
| .| ..||| ||...| .|| .. | ||||| .. . . |. .||| ..| |||.||... | .|||.|||.| .. . .|||.
vakkpqnkeknryadiialdssrvvLekekg.dkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
RCGETVSHpetalglaLDVTLKEERETGPWIERDLIVETLRPDHTkmvRHVKQFHYTSWPDHGVPASPETFLEFLlavkqhhDAVQRQSQTAGepQSPLV
|. . . |.|... | . .. | |.. . . |.|.|.|...||| |||. .. ||.| . ||.. | || ..|..
ekaekyGd........vtvsllskeefadytkrklklskakkade...rivrqlhfvvWPdkgvPevatavLell.......kkvqasqqqag..naPvi
VHCSAGVGRTGTFCCVYGVVA
|.|||||||.|.|. .. |.
vqCsaGvgrsGafiaidavle
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 846-1093 | 5.5e-45 | 148.3 | In-house | 12-242 (287) | alignment | ||
Range on Protein: 846-1093
Range on HMM: 12-242/287.0
FDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGStdDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVI
|||. | . . | .| .||| |.||.| ||| . . .|| ||||| .| | | |..|||| .| .|||..|...|| ..
vdkevdalkedsesstatfkaaeelaavkknryadvlPiddtrvllsaegelGs..dyinanyvasytdd.eafiaaqgPiaatvrdfwravletrsasv
VMVTNLEERGRPKCDRYWPARcgetvSHPETaLGlALDVT-LKEERETGPWIERDLIVETLrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVK
...| | .| || .||| | | .| |. |. . . | | . | .|. | |||... ||||.... . .. | | ||
itmtreveearlkcykywPer.....evPmr.vG.GysvvlldydikePeygvralrlidl...etrearvvkqldllswPdkvlaPtavglirfvldvk
QHHDAvQRQSQTAGepqsPLVVHCSAGVGRTGTFCCVYGVVAALPYVGN
|| .. .|... .| |||||...|.||.|.. .. .| | .|.
qhiel.ardasevG....PlvvhddvGiGrsGillatlvlvsrledlGr
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 838-1081 | 1.6e-44 | 147.0 | In-house | 14-231 (287) | alignment | ||
Range on Protein: 838-1081
Range on HMM: 14-231/287.0
AYPDGKSGFDKEFALLEMEDAAHNRdTSCAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMV
|. || . |..|| . .. . |..| |.||...||..| || .. | .|||||... . . |. |..| .| .|||..
ghakgnegfknqftvleqvtqrede.vthniasqnkdknRltqilvpdnyrvllk.....gehpdyinavfidgykek.kafiiaesPmfntarnfWkli
VQQRSRVIVMVTNLEERGRPKCDRYWPARCGetvshpeTALGlALDVTLKEERETGPWIERDLIVETLRpdHTKMVRHVKQFHYTSWPDHGVPASPETFL
... .|||.....| . .| .||| . || ..| .| . .|||.| |. ... ..|||...|.|...| ..|.| |
ddrnvtaivmlcqekendeevcyqyWpeeks.......vvlG.eyniellneevnagyierklevknkn..kagdkqqvkqyqitnWdstgkvtepqtil
eflLAVKQHHdavQRQSQTAgepQSPLVVHCSAGVGRTGTFCCV
| ... . | . . ....|||||..|||...|| .
...lvieemy...ktqrkrg...ntsivvhCsdtvGrsamfcaa
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 863-1087 | 4.5e-44 | 145.7 | In-house | 41-243 (297) | alignment | ||
Range on Protein: 863-1087
Range on HMM: 41-243/297.0
DTSCAAAER-NVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSgcpDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRpKCDR
.. | .. | ...||..|||||. ||..... ||.|| .|.. ... | |...| |||.||.... .|||.....|| . || |
qpqtvaekkvnfeksRYkniLPydssRvkLaivnd.dpdsDyvnasfvkgnkh...rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcar
YWPARCGETvshpetaLGlALDVTLKEERETGPWIERDLIVETlrpDHTKMVRHVKQFHYTSWPDHGVPA--SPETFLEFLLAVKQHHDAVQrqsqtage
||. . | .| . |.|. | |.|.| |. ...|. | |||.....|||. |. | ...|... |..... ..
yWsdkgvtt.......fG.dvsvvllsvsereGfikrelevtk...gkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqna........
pQSPLVVHCSAGVGRTGTFCCVYGVVAA
..||.|||.||||||| .. . |||
.egPllvhclaGvGrtgvlltidsvvae
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 862-1087 | 5.3e-44 | 145.3 | In-house | 34-236 (315) | alignment | ||
Range on Protein: 862-1087
Range on HMM: 34-236/315.0
RDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDR
. | . | .|||..|||.|..|| ..|. .||||| ...|. . ....|||.... |||.||.|.. |||||...| . || .
yrqrvaretinfkknryknilPldsarvklevidds.Pdsdyinasyiksvddd.kayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrq
YWPARCGETVSHPEtalglaLDVTLKEERETGPWIERDLIVetlRpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVqrqsqtagepQ
||| | ...| . . |.| . .. . | |.. | ... | | ||..| |||.||. ..|... .|| .. .
ywPdrkadsvefGs......ikvellsleadtdgvarklvt...r..kseesrtvtqfqftewPdkGvdkqtssllklikevkadngkk..........e
SPLVVHCSAGVGRTGTFCCVYGVVAA
.|.||||||||||| .. . |||
fsllvhcsaGvGrtGvvisidevvaq
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 832-1084 | 2.3e-43 | 143.3 | In-house | 12-235 (315) | alignment | ||
Range on Protein: 832-1084
Range on HMM: 12-235/315.0
VAHLQQAYPDGKSGFDKEFALLEMEdAAHNRDTscAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSGcPDFVCAQGPKHSTSG
.... | | || ... . | |. | |...||| .|..||..||.. .| . ||.|| . . ...||||. .. .
ityvaqkkastkngfkqdyesipgg.qlhpldv..akkienkqknryiniiaydksrvqlpllen.dphsdyvnanfidGynkk.rryiaaqgpnvasvk
DFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcgetvshpETALGlALDVTLKEEREtgpwiERDLIVETLRPDHTKMVRHVKQFHYTSWPDHGVPA
|||..| .. |||.||| |. . |...||| . . | . ||.|.| . .. | || . .|.| |.||||||| |||.
dfwrlvfeedigkivmltnlvegekrkaekywpdk........kviyG.kitvtrkseev.....nteytvrtlsvvfgdnirevvqlhytswpdmgvpk
SPETFLEFLLAVKQHHDAVQrqsqtagepqSPLVVHCSAGVGRTGTFCCVYGV
. ..... |||||.. ...||||||||||||||... |
ytiplmnlirtvkqhhtnsv..........gaivvhcsaGvGrtGtfitldav
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 829-1082 | 4.9e-43 | 142.1 | In-house | 8-237 (290) | alignment | ||
Range on Protein: 829-1082
Range on HMM: 8-237/290.0
SETVAhlqQAYPDGKSGFDKEFALLEMedAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGS-TDDYINACHVRSLTSgCPDFVCAQGPKH
.|.|| . |..|| ..| |. .... . . .. | .||...|..|| |. .. ..| |..|||||.. ... .||| .
gefva...nghakgnegfrnqfkmlds..gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgyke.kkqyiatqgpvs
STSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETvshpetaLGlALDVTLKEERETGPWIERDLIVETLRPDhtKMVRHVKQFHYTSWPDH
.| ||||...|... .|||.|| | |. || |||.. .. .| ..| .|... ||| | |. . . . ..|.|.. |.|...
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka.......yg.efsikllneetlneyierklevknknsa..gakqsvtqyqitnwdst
GVPASPETFLEFLlavkQHHDAVQRQSQtagepQSPLVVHCSAGVGRTGTFCCVY
| . |.| | . .. ||.. . ..|||||..|||...|| ..
gkvtnpqtillvi....eemyktqrkrg.....ntsivvHCSdtvgrsavfcaaa
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 872-1152 | 7.3e-43 | 141.6 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 872-1152
Range on HMM: 1-172/182.0
NVDRNRYRDILPYDRTRvhmqvlpgygsTDDYINACHVRSLTSGCPdFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTnleergrpkCDRYWParcgetv
|.|.|||.||||||..| ||||| ... .. |...||| || ||..|. ... ..||..| ...|||
nldknrysdilpydhsr...........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywp.......
shpetalglaldvtlkeeretgpwierdlivetlrpdhTKMVRHVKQFHYTSWPDHGVPAsPETFLEFLLAVKQhhdavqrqsqtagePQSPLVVHCSAG
.. |.. |..|..||||||| ....|.|. .|.. .. | .||||||
......................................ellerlgiqylylpwpDhgvpd.ldelldfieevle..............eggpvlVHCsaG
VGRTGTFCCVYgvvaaL---PyvgnglpllaaresgaqrptresqggKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAAR
||||||... | | .... ..|. .|. | ||.| .|| |..|| || .
vgRtgtlvaay.....lmkkl..........................gvsleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 836-1082 | 2e-41 | 137.3 | In-house | 26-245 (319) | alignment | ||
Range on Protein: 836-1082
Range on HMM: 26-245/319.0
QQAYPDGKSGFDKEFALLEmEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGStDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWK
.. . | .. . || . . .. | . | ..| |.||. .||..|...| .. | | ||||| .| . .. ||||. | |||.
ksdfdddltklevefrrac.klgvnladqtfanldqnkdknriinilafdknvvklerliGeef.sdyinasfvtGyqrk.dkyiaaqGPldntladfWr
MVVQQRSRVIVMVTnleergRPKCDRYWPARCGETVSHPEtalglaLDVTLKEERETgpWIERDLIVEtlRPDHTKMVRHVKQFHYTSWPDHGVPASPET
|. .... ||..| . || .||| . .. . . ..|.. || . .. ||. . . . | .|...|||. |||.||| .|
miweyncstivllt......kdkcsqywplkivikeerfk......vkvdsveetae..yvvrdiels..edgkekdirkitqfhflGwpdvGvpdypsd
FLEFLLAVKQHHDAVQRqsqtagepQSPLVVHCSAGVGRTGTFCCVY
.. .. |. .. . . ..||||||||||||.. .
lmrlvkkvrhltskenh........ranivvhcsaGvGrtGvyivld
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 848-1081 | 1.9e-40 | 133.9 | In-house | 25-249 (418) | alignment | ||
Range on Protein: 848-1081
Range on HMM: 25-249/418.0
KEFALLEmeDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLTsgCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVM
.|| ||| .. .|| ..| .||| .||| ..|||... . ||||| .. .|.|.||| | |||.|| ..| |.|||
eefrlle..esvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdk.egsdyinanyidgay..pkqfictqgplpntiadfwrmvwenrcriivm
VTNLEERGRPKCDRYWPARCG-ETVSHPETALgLALDVTLKEERETGPWIERDLIVETLRPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQH
.. | | ||||||| . | | .| . | | ||..| .| | . |..| |||| .| . | ..| .. ..
lsresencrikcdrywpeqiggeqfsiygngn.evfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnr
hdavQRQSQTAGEPQSPLVVHCSAGVGRTGTFCCV
| | . . . |..||||||||||||||
....qnqiipssdrnvpiivhcsagvgrtgtfcta
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 863-1082 | 3e-40 | 133.5 | In-house | 16-209 (284) | alignment | ||
Range on Protein: 863-1082
Range on HMM: 16-209/284.0
DTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGStDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTnleergRPKCDRY
| . | ..| |.||. .||..|...| .. | | ||||| .. . .. .|||. | |||.|. .... ||..| . || .|
dqtfanldqnkdknrighilafdknvvklerliGeef.sdyinasfitGyqrk.dkyiatqGPldntladfWrmiweyncstivllt......kdkcsqy
WPARCGETVSHPEtalglaLDVTLKEERETgpWIERDLIVEtlRPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVQRqsqtagepQS
|| . .. . . ..|.. || | .. ||. . . . | .|...|||. |||.||| .| .. .. |. .. . ..
wplkivikeerfk......vkvdsveesee..yvvrdiels..edgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenh........ra
PLVVHCSAGVGRTGTFCCVY
..||||||||||||.. ..
nivvhcsagvgrtgvyivld
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 814-1086 | 9.6e-40 | 131.1 | In-house | 2-249 (297) | alignment | ||
Range on Protein: 814-1086
Range on HMM: 2-249/297.0
EEAGESNLDVAIRALsetVAHLQQAYPDGKSGFDKEFALLEMEDaAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLT
||. ||||.. . | . . |. ..||. | . |... .. | ||.||..||....|||| .||... ...||||| .
eepvvsnldistGhv...vlsyledhlknkdrlekewealcaye.aepstkevakaeknvkknrskavlpydhsrvklkeeas.aeksdyinasaildhd
SGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGEtVSHpetalglALDVTLKEE-RETGPWIERDLIVETLRpdhTKM
| .. .||| || |||.|| .| . |||..|.||| | .|.|||| | | | . .| | | . .. | . . |. |.
prapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGse.vyh.......iyevhlvsehiwcddylvrsfylknlq...tse
VRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAvqRqSqtagepqSPLVVHCSAGVGRTGTFCCVYGVVA
| | |||. |||..|||||. ..||| | . . | | .|.|||||.|.||||... . |..
trtvtqfhflswpeegvPasaksllefrrkvnksyrG..r.s.......cpivvhcsdGaGrtGvyilidlvln
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 872-1082 | 1.9e-39 | 130.3 | In-house | 3-193 (237) | alignment | ||
Range on Protein: 872-1082
Range on HMM: 3-193/237.0
NVDRNRYRDILPYDRTRVhmqVLPGYGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPArcgetV
| .||| .| || .|| || | ||. |||||...... ...|||| |. |||.|| |.. ||||.| | |. . || .|||
nkiknrygnivaydhsrv...vlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywps.....t
SHPEtALGlALDVTLKEERETGPWIERDLIVETLrpDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVqrqSQtagepQSPLVVHCSAG
|. | | | |.|| . | . | |.. . . | || ..|...|||||.||| ..| | . .. | |. .| ..|||||
dqpa.ayg.vltvslkkkeefsdytvrslllskr..ltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphv...se.....sgpwiihcsag
VGRTGTFCCVY
||||| | .
vgrtgiflvid
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 900-1154 | 2.9e-39 | 130.7 | In-house | 3-228 (272) | alignment | ||
Range on Protein: 900-1154
Range on HMM: 3-228/272.0
TDDYINACHVRSLtsGC---PD-FVCAQGPKHSTSGDFWKMvVQQRSRVIVMVTNLEERGRPKCDRYWP----ARCGETVSHPETALGLALDVTLKEERE
...|||| .| . | |. . ...|| . | |||.. ... ..||.....||||| ||||||| .. ....| | .|| ||| .|
lsgyiNardvggy..grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
TGPWIERDLIVETLRPDHTKmvRHVKQFHYTSWPDHGVPASPetFLEFLLAVKQhhdavqrqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVAAlpyv
. .| | |... | . .. |.| ..|||.||||||| .. .||.| .. . . |..||||||..||||..... ...
lldyilrellltlllsagea..revmhlhytdwpdhgvpqea..llellellld...............ggpvlvHCsaGkdRTGtvvallllllg....
gnglpllaaresgaqrptresqggkLD--------------IMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARRY
.. . ..|...|. |. .||| .||.|.| | ||..|..
.........................vsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 862-1079 | 6.3e-39 | 128.6 | In-house | 21-246 (297) | alignment | ||
Range on Protein: 862-1079
Range on HMM: 21-246/297.0
RDTSCAAAERNVD--RNRYRDILPYDRTRVHMQVLPgygSTDDYINACHVRSLTSGCP-DFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPK
| | ..| || .||||||| .| |||... . . ||||| .| . ...|||| ..| |||..|..| ||||||..|.| || |
rgesfssakrnsslrknryrdilatddtrvkllrvi...terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdk
CDRYWPARCGETVSHPETALGLAlDVTlKEERETGPWIERDLIVEtlrpdhtKMVRHVKQFHYTSWPDHGVPASPETFLEF-------------LLAVKQ
| ||| .| .. . | .| .. | || . |.|. . ||||||||. | | .||. .
capywpsvvqerlkagdvvvefl.sst.sdefdrviltelqliyr.......sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalve
HHD---AVQRQSQTAGEPQ-SPLVVHCSAGVGRTGTFC
.| .| | |. .|.|||||||||.|
mftamvflqleslraemprnayllvhcsaGvGrsGvvv
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 869-1158 | 7.2e-38 | 126.4 | In-house | 43-287 (314) | alignment | ||
Range on Protein: 869-1158
Range on HMM: 43-287/314.0
AERNVDRNRYRDILPYDrTRVHMQVLPGYGstDDYINACHVRSLtsgcPDFVCAQGPKHSTSGDF----------WKMVV--QQRSRVIVM---------
..| |.||| ||||.| .||. . ||..| ||||| .|.. .|...|||. | || |.||. ....|.|||
lflnrdknryldilpad.nrvilpglpvsg..sdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlade
------------VTNLEERGrpkcdRYWPARCGETVShpetalglaldvtlkeeretgpwierdliveTLRPDHTKMVRHVKQFHYTSWPDHGVPaSPET
..| ..| ...|. |. . |. . |.. ..... .||...| ..|
lsrLdaAlgKtpllildgng.....neptaadlellk...............................eelydpelferlgikylripvpDgsap.lled
FLEFLLAVKQHhDavqrqsqtagePQSPLVVHCSAGVGRTGTFCCVYGVVAALPyvgnglpllaaresgaqrptresqggkLDIMNIVSRMREDRR----
|.||| ..... | ...|..|||.||.||||||.... .. .| ... .....|. |
fdeflefieea.d...........kggpvlvHCkaGkgRtgtfvvaaylmkllg...........................vsleealedvrlkRpinpn
-FMVQTVDQYKFCYLASLEAARRYNDKY
.... .|| |.. |.||. ... ..|
pgfieqleqyefilealleylkflkkfy
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 863-1081 | 1.5e-36 | 121.0 | In-house | 31-229 (307) | alignment | ||
Range on Protein: 863-1081
Range on HMM: 31-229/307.0
D-TSCAAAERNVDRNRYRDILPYDRTRVHMQVlpgYGSTDDYINACHVRSLTsGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDR
. . | . | |.|||.|. |..|. ... | . ||| | .. . |.|||||...| .|| |..|.. ..|. .. | .. ||..
egvtveafsantdknryqdvkcqdkgrivvkf...dglasdyihanylgiai.kpkkficaqgplentqysfwamaiqekvesvimlckvielakikceq
YWPARCGETVSHPETALGLALDvtLKEERETGPwIERDLIVETLRPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHhdavqrqsqtagepQ
|||. |.. . |.. .... .. | | . | ||. | .. | .... .. |||.||| | ...| ||. . .
ywpleegqklvfgeapntisva..nlgakklap.dedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavryd..............t
SPLVVHCSAGVGRTGTFCCV
|.||||||||||.|| ..
npvvvhcsaGvGrsGtivai
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 845-1081 | 3.4e-36 | 119.5 | In-house | 16-246 (301) | alignment | ||
Range on Protein: 845-1081
Range on HMM: 16-246/301.0
GFDKEFALLEmedAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYG-STDDYINACHVRSLTSgCPDFVCAQGPKHSTSGDFWKMVVQQRSR
.|.... |. .... .. |.| ||...| .|| |. .. | . .. .|||| .. . .. |. |||| ..| |||....|..
kfeeqykelk...egedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgyse.kkkfiaaqgpmkktlvdfWrliwqekpv
VIVMVTNLEERGRPKCDRYWPARCGETVSHpetalgLALDVTLKEERETGPWIERDLIVE------------TLRPDHTKMVRHVKQFHYTSWPDHGVPA
|||||||.|. . || .||| |. . . |||..| .. |.| | ... ...| ..| |.. |.||..||
sivmvtnlkegtkskceqywpnseaeseef......gpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvr
SPETFLEFLlavkqhHDAVQRQSQTAGepqSPLVVHCSAGVGRTGTFCCV
| | |. . .| ..|| . | .|.|||||..|.|.|..| |
eprtvLqvi......ddvihrqqkigg...gpvvVHCSdtVsrsGvYcsv
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 901-1148 | 9.7e-36 | 118.5 | In-house | 12-170 (176) | alignment | ||
Range on Protein: 901-1148
Range on HMM: 12-170/176.0
DDYINACHVRSltsgcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVshpetalglaldvtlkeeretgpwierdl
||||| . . . ... ||| ..| ||..|. ... ...|..|.. | || ||..||| .. .
ldyinanlilg.....srpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.............................
ivetlrpdhtkmvrhvkQFHYTSWPDHGVPASpETFLEFLLAVKQHHDAvqrqsqtaGepqSPLVVHCSAGVGRTGTFCCVYGVvaalpyvgnglpllaa
|.... ||||||| . | .||.| ..... .. | | .||||||.|||||... | .
.................qylhlpwpDhgvpdl.elllellefirealke........g...gpvlVHCsaGigRtgtlvaayll................
resgaqrptreSQGGKLDIMNIVSRMREDRR-FMVQTVDQYKFCYLASL
. |.. ......|| |. ..||| .||.|.| . |
...........elekglsveealalvreqRplgavqtpeQyrflyefel
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 901-1144 | 1e-35 | 118.3 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 901-1144
Range on HMM: 2-163/174.0
DDYINACHVrSLTSGCPDFVCAQGPKHstsgdFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPArcgetvshpetalglaldvtlkeeretgpwierdl
.||||| .. .|. | ... ||| ||.|. .......||.....|.|. || .|||
sdyinaspl.dlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...................................
ivetlrpDHTKMVRHVKQFHYTSWPDHGVPASPEtFLEFLLAVKQHHdavqrqSQtagEPQSPLVVHCSAGVGRTGTFCCVY--------GVVAAlpyvg
... ..|.. |..|. ||||||| ... .|||. .|.... |. |. |..||||||||||||... | ..| |
.......lredlerlgiqylylpwpDhgvpdlsi.llefvkfveeal......se...dpggpvlVHCsaGvgRtGtlvaaylmlrglleslvda.....
nglpllaaresgaqrptresqggkldiMNIVSRMREDRRFMVQTVDQYKFCY
...| ..| | |||| .||.|.|
...........................ldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 900-1144 | 2.1e-35 | 117.3 | In-house | 4-154 (172) | alignment | ||
Range on Protein: 900-1144
Range on HMM: 4-154/172.0
TDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLeergrpkcdrywparcgetvshpetalglaldvtlkeeretgpwierd
.||||| .. .|. ..|.. ||| .| |||.|. .. ..||..|.|
gsdyinasyl.dlyyipdrfiatqgplrntladfwrmlkelgithivnltel................................................
livetlRPDHTKMVRHVKQFHYTSWPDHGVPaSPETFLEFLLAVKQHHdavQ--RqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVaalpyvgNGLpl
| .. .|.. |..|..||||||| ..| .|||| ..... . . . | .||||||||||||... | . ||
......lydpellerlgiqylylpwpDhgvp.llellleflefidell...alsp........ggpvlVHCsaGvgRtgtlvaaylml.......lgl..
laaresgaqrptresqggklDIMNIVSRMREDRRFMVQTVDQYKFCY
.. ..|. .|| |. .||. .||.|.|
....................sleeavalvrekRpgavqnpsqyrfly
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 862-1086 | 5.1e-35 | 115.6 | In-house | 35-194 (392) | alignment | ||
Range on Protein: 862-1086
Range on HMM: 35-194/392.0
RDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLTSGCpDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGrpkcdr
....| | |. .|||..|||||..||...|. . .||.|| ...|. . ....|||. .. |||.|| |.. |.|||.|.|
ypqtvaqkeinlkknryknilpydsarvkleviddi.pdsdylnasyipsfdnek.ayiasqgpnaaslddfwrmvfqenvttiamvtklkegd......
ywparcgetvshpetalglaldvtlkeeretgpwierdlivetlrpdHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHdavqrqsqtaGEPQ
. . .| | |||.| |||..|| ..|.|. || .. |.
...............................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadf..........Gqyt
SPLVVHCSAGVGRTGTFCCVYGVVA
||..|||||||||| .. |||
hpliihcsagvgrtgvvisidsvva
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 834-1080 | 1.1e-34 | 114.7 | In-house | 10-231 (439) | alignment | ||
Range on Protein: 834-1080
Range on HMM: 10-231/439.0
HLQQAYPDGKSGFDKEFALLEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGStDDYINACHVRSLTSGcPDFVCAQGPKHSTSGDF
|... . . |...| .. . .. ..| || | . .|||.|. ..| ||| .| .|| |||| ... .. .||||. |. ||
hvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvph.shyinanyikGyydd.klyiatqgpkkettddf
WKMVVQQRSRVIVMVTNLEERGRpkcdrYWPARcgETVSHPETAlglaldVTLKEERETGPWIERDLIVETLRpDHTKMVRHVKQFHYTSWPDHGVPASP
|..|..... |||.||| | . |||. . | . . | | . | .. | . | | |.|. | | ||||..|||. |||
wrlviekktvtivmltnlvesyk.....ywpsd..aevcygdia......vrvdrnielpnyvirgfkvfner.dttekertvlqfhyiawpdknvpaqa
ETFLEFLLAVKQHHDAvqrqsqtagEPQSPLVVHCSAGVGRTGTFCC
|.|| |.. | | |.||||||||||||| .
shvldflrainsandk.........eeygpvvvhcsagvGrtGtiia
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 855-1081 | 2.3e-34 | 113.4 | In-house | 23-243 (296) | alignment | ||
Range on Protein: 855-1081
Range on HMM: 23-243/296.0
MEDAA--HNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYGSTDdYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLE
.. .. .. | .. . | ..||. ...||| .|| .. | | ..| |||| .| |.. ... ..||..| ..||..| .. . .|..|.
lkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksd.Yinavyvdsflkk.keyivteapkketvdefWrlvydeeisavvvLtktf
ERGRpKCDRYWPARCgeTVSHPETALGLALDVTLKEERETGPWIERDLIVETL-RPDHTKMVRHVKQFHYTSWPD-HGVPASPETFLEFLLAVKQHHDAV
. . .. ||| . . | . . .. . . . . .. | . . . .| ||.|..| |. . || | ....|.. |.. . |
dfak.mypsywpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekv
qrqsqTAGEPQSPLVVHCSAGVGRTGTFCCV
. ..|.||..| |..|.| .. .
.....dedpeegPvvvvssdGasRsGvylai
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 919-1144 | 4.5e-34 | 112.7 | In-house | 11-143 (152) | alignment | ||
Range on Protein: 919-1144
Range on HMM: 11-143/152.0
FVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWparcgetvshpetalglaldvtlkeeretgpwierdlivetlrpdhtkmvrhvkQ
|...||| | |||.|. .. ..|||.|.|.|.|..||..|. |
fiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi......................................................q
FHYTSWPDHGVPASPETFLEFLLAVKQHhdavqrqsqtAGEPQSPLVVHCSAGVGRTGTFCCVYGVVaalpyVGnglpllaaresgaqrptresqggkLD
.... ||||||| ... .|..||..... | ... | .||||||||||||... | . | ..
ylhlpwpDhgvpdlsqlllflllfiekl..........aldkggpvlVHCsaGvgRtgtlvaaylml.....lg........................vs
IMNIVSRMREDRRFMVQTVDQYKFCY
. ..|...|| | .|.. .|..|.|
leeavalvrekRpgavpnpgqlrfly
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 859-1083 | 5.9e-34 | 112.2 | In-house | 20-221 (283) | alignment | ||
Range on Protein: 859-1083
Range on HMM: 20-221/283.0
AHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGygstdDYINACHVR--SLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGR
..|. .|.|..| ||...|.|.|. ||... .. |||||... ... ||.| . | |||||| ... |||.|.| | |
vpdldadiasadenkrknrnqeivpadqwrvelksesr.....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlr
PKCDRYWPARCGETVShpEtalglaLDVTLKEERETGPWIERDLIVETLRPDHTKMVrhVKQFHYTSWPDHGVPASPETFLEFLLAVkqhhdAVQRQSqt
|| .||| | | | . |||..| .| . |.. . ..... . . . | . | | .... | . . . |..|
ikCsqyWPkrGsedyG..e......ftvtlrkettsnsfiikelllrvnssakstll..lahyqvidWleygeqaiinslvkfnkvi.....slqtes..
agePQSPLVVHCSAGVGRTGTFCCVYG
...|.|||||.|.|||..|. .
...kkgPivvhCstgiGrtavfiaasa
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 871-1084 | 5.9e-33 | 108.7 | In-house | 55-239 (290) | alignment | ||
Range on Protein: 871-1084
Range on HMM: 55-239/290.0
RNVDRNRYRDILPYDRTRVHMQvlpgYGSTDDYINACHVRSLTsgcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGET
.. .|||.|. |.||| .. | ||. | .|. | . |. .||. ..| |.|.||.|.. .|||. .| | |..||..|.| . ||.
tefkknrykdvvcndktrvilk....dGydGdyvhanyvkGlk...amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGev
VSHPETALGlaldVTLKEERETgPWIERDLIVETLRPDHTKMVRHvkqFHYTSWPDHGVPASPETFLEFLLAVKQHhdavqrqsqtAGepqsPLVVHCSA
.. | .. ........ | . | | . ....| .. ||||. |. | ..| | .... .| |.||||||
ltfGeitvl....cseeddkda.niikktlsvrdkdsGkehklkh...lkikswpdksvalstlallrtlrilrka..........sG....pvvvhcsa
GVGRTGTFCCVYGV
|.|||||| .
GiGrtGtfvaievg
|
|||||||||
| ALIX_LYPXL_bnd | ALIX V-shaped domain binding to HIV | 480-727 | 5.4e-32 | 99.2 | Pfam-A | 28-293 (296) | alignment | ||
Range on Protein: 480-727
Range on HMM: 28-293/296.0
EA-----AQRLEQAQEHLAGFQERFEAAAAKFESARKMA------------SDRLRQEHDDMKSSLQQAQQAVRLARDKLEAIEPRLQLLASPHDDLRAA
|. ... ..... | .|.... . . |. |.. .. ||.| .....|..|... . .| |||.||. |.||.|| ..|.|.
eeslddleelkqavesildeakeqLdeeesedeklrskygarwtrqpsseltaelreelrkyreaLeeAsesDsqlrskleeieedlalLsspeeeleas
MPKASLMDLDVGtldADKAKRIEELLGKVQIMRQLRQDKWDEFRREAeKIDIGHQILT-CP-----DQDALMREALQPLDELRDQLQSNFDSQRRLLPVL
.|. | .. | ....||..||| |.. ... |. .| .... . |. .||. . ....|..|.|. |.|...|... |..|| |
lpssspeesdev...seqikrlrelleklnllkaeRaklleeLkeki.hdddiskilielnkksssneeqlfeeeLekfdplqerleqsiskQssllkel
VEVYASQGKARKHIKEVqDQQRAFIEGLLGAFDAFRAVQDRVHKLTDFETAFESRLRAFEQQSQQLEQAQT
|.... ...|. .| .. ... | |.|... ... . . ..| . ....| ..... ... .|..
keaneeflqdkkskyek.kerekvlqklenaydkykelssnleeglkFYndLlkileslrknvkdfvnarr
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 871-1081 | 8e-32 | 105.3 | In-house | 7-194 (239) | alignment | ||
Range on Protein: 871-1081
Range on HMM: 7-194/239.0
RNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcget
| .||| .|. ||..|| .. | ||||| ..| ....|| .|||||.|. |.| ||||.| | | . || .|||
vnkaknryanivtydhsrvvleklsn.dphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds....
vshpeTALGLALDVTLKEERETGPWIERDLIVETLRpdHTkMVRHVKQFHYTSWPDHGVPASPETFLEfllavkqHHDAVQRQSQTAgepQSPLVVHCSA
|. | |||.. .| | ... . .| |.| |.|.| |||.||| . | . . ..| | |.||||
.....tskycnlrvtlrktevfadyiirtfvmsqvg..qt.eeryvyqyhftvwpdkgvpqyatavlg.......lrrkitkdslpg...arpwvihcsa
GVGRTGTFCCV
||||||.| .
gvgrtgaflvi
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 871-1081 | 8.8e-32 | 105.2 | In-house | 6-193 (239) | alignment | ||
Range on Protein: 871-1081
Range on HMM: 6-193/239.0
RNVDRNRYRDILPYDRTRVHMQVLPGyGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARcget
| .||| .|. ||..|| .. | ||||| ..| ....|| .|||||.|. |.| ||||.| | | . || .|||
vnkaknryanivtydhsrvvleklsn.dphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds....
vshpeTALGLALDVTLKEERETGPWIERDLIVETLRpdHTkMVRHVKQFHYTSWPDHGVPASPETFLEfllavkqHHDAVQRQSQTAgepQSPLVVHCSA
|. | |||.. .| | ... . .| |.| |.|.| |||.||| . | . . ..| | |.||||
.....tskycnlrvtlrktevfadyiirtfvmsqvg..qt.eeryvyqyhftvwpdkgvpqyatavlg.......lrrkitkdslpg...arpwvihcsa
GVGRTGTFCCV
||||||.| .
gvgrtgaflvi
|
|||||||||
| PTPc_DSPc_SM00012 | 1016-1148 | 1.2e-30 | 101.2 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 1016-1148
Range on HMM: 2-104/105.0
VKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVQRqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVGnglpllaaresgaqrptresqgG
||..|||.||||||| ... .||.| |||... . .. ..|.||||||||||||||.... .. | . .
vkhyhytgwpdhgvPeesdsilellravkknknkses........skpvvVhCsaGvgRtgtfvaldillqqleket......................k
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
..|| .||...|. |. |||| .|| |.| | |
evdifqivkelrkqRpgmvqteeqylflyrall
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 855-1081 | 2.6e-30 | 100.1 | In-house | 41-241 (305) | alignment | ||
Range on Protein: 855-1081
Range on HMM: 41-241/305.0
MEDAAHNRDTScaaAERNVDRNRYRDILPYDRTRVHMQVLPgygsTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEER
| ..| | . | |. .. .|||.|. |.. |... . ||| | .| |.||||| | .|| ||.|.. |||. . |
mtqvafnanqs...adiaitknryqdvpcqdqsavkldkps....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvel
GRPKCDRYWPARCGETVSHPETALGLalDVTLKEERETGPWIERDLIVETLRPDHTKMVRHVkqfHYTSWPDHGVPASPETFLEFLLAVKqhhdavqrQS
|. || .|||| || .. . .|. | . |. |. | |.. |||. ..| ||| ||| | ||.| |.. |
gklkcaqywpaaqgeklelksgivve..nvsgskpmerdaeiqitllnltysgdqkmsvrhl...qwtewpdrgvppckltslellsair........gs
qtagepQSPLVVHCSAGVGRTGTFCCV
. |.|||||||.||||| ..
......kvpivvhcsagigrtgtivai
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 883-1145 | 6.9e-30 | 99.4 | In-house | 1-165 (178) | alignment | ||
Range on Protein: 883-1145
Range on HMM: 1-165/178.0
PYDRTRVHMQVLPGYGSTDdYINACHVRsltSGcpDFVCAQGPkhstsGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGetvshpetalglal
|.|||||... |.|. ..| ||||... | ......| |..... .. ..||..|. |.|..|||.||| . |
pldrtrvllsnleglersd.yinaseil...pg..lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag..............
dvtlkeeretgpwierdlivetlrpdhtkmvrhvKQFHYTSWPDHGVPASPETFLEFLLAVKQHHdavqrqsqtaGEPQSPLVVHCSAGVGRTGTFCCVY
|.... .|||||| ..| ||||. ...... |...| .|||||||||.||... |
..................................iqylhipipDhgvpdllehflefvefieeal..........dekggpvlVHCsaGvgRsgtlvaay
GVVAAlpyvgnglpllaaresgaqrptresqggKLDIMNIVSRMREDRRfMVQTVDQYKFCYL
. .|.. ......|| |. .|.. .|....|.
lmkkl............................glsleeaielvrerRp.ivpnpgqlrqLye
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 834-1082 | 7.5e-30 | 98.7 | In-house | 12-240 (305) | alignment | ||
Range on Protein: 834-1082
Range on HMM: 12-240/305.0
HLQQAYPDGKSGFDKEFALLEMEDAAHNRDTSCAAaeRNVDRNRYRDILPYDRTRVHMQvlPGYgsTDDYINACHVRSlTSGCPDFVCAQGPKHSTSGDF
.... | |. .||. .. . . . | .. ..|||.|. |. ||... . . .|| | .| . . |.|.| | . | ||
fvkrtlekgpaglraefvamkrfndfekmkafkea..qeagknrykdvgcldnnrvkle..gpw..pheyihanyvst.ptnpkrfictqaplektcadf
WKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPETALGLAL----DVTLKEERETGPWIER-DLIVETlrpdHTKMVRHVKQFHYTSWPDHG
| | .|.. | |. || |.| || |.... ..... | ... |||| .... ... |..| . .|.|...|. ||| |
wymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlvieg....pgekarkvthyhwidwpdrg
VPASPETFLEFLLAVkqhhdavqRQSqtagepQSPLVVHCSAGVGRTGTFCCVY
|||. . ||.| | | . |.|||||||.||||. .
vpaadlailelleka........rps......kgpivvhcsagigrtgsvvmle
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 901-1146 | 1.3e-28 | 94.9 | In-house | 3-148 (151) | alignment | ||
Range on Protein: 901-1146
Range on HMM: 3-148/151.0
DDYINACHVRSLtsgcpdFVCAQGPkhstSGDFWKMVVQQRSRVIVMVTNLEERGrpKCDRYWPARCgetvshpetalglaldvtlkeeretgpwierdl
.||||. | . . . .|| . ||.... .. ..||.....|||| .| .|.|.
sdyinfsyvtgg......lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
ivetlrpdhtkmvRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQhhdavqrqsqtagEPQSPLVVHCSAGVGRTGTFCCVYGVVAAlpyvgnglpllaa
..|.......|||.|.| |....|||| .. . .. |..||||||.|||||....| .
.............ievlhipildwpdpglplsfdavleflellld.............kkngpvlvHCsaGkgRTGtlvalylmllg.............
resgaqrptresqggkLDIMNIVSRMREDRRFMVQTVDQYKFCYLA
... ... .|. | .||. .|. |...|
................vsleealeeyrlkrpgvvqpnqqflfqlfa
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 871-1080 | 2e-28 | 94.2 | In-house | 42-223 (288) | alignment | ||
Range on Protein: 871-1080
Range on HMM: 42-223/288.0
RNVDRNRYRDILPYDRTRVHMQvlpgygSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGET
| |.||... | |||... |. |..| | . ..||| | ..| . .|||.... . |||...| |.|..| . |.| . ||.
anptrdryenlprcditrvkls......ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGek
VSHPETalglaldVTL-KEERetgPWIERDLIVETLRPDHTKMVRH-VKQFHYTSWPDHGVPASPETFLEFLLAVkqhhdavqrQSQtagepQSPLVVHC
. | |..| |.. . | .|| .. . ||. |. |.|.||| . ..| .| . .| | |.|||.
arigrl.......ctvvkkkr...adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.........ksl.....qkPivvhs
SAGVGRTGTFCC
|||||||||.
saGvGrtgtlil
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 873-1046 | 2.2e-27 | 90.6 | In-house | 29-193 (319) | alignment | ||
Range on Protein: 873-1046
Range on HMM: 29-193/319.0
VDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGetvs
|..|. ...| ||| .| . | |..| .|| . ...|| . ..| |||..| .|.||||| .|.| | | .| .|.|.. .
kdksrvinvvPlPetrvvlqrigdd.dkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtket....
HPETALGLALDVTLKEERETGPWIERDLIVETLrpdHTKMVRHVKQFHYtSWPDHGVPASPETFLEFLLAVKQH
..| | . ||||. .. |.. . . .. |.. . | |.. .|||...... || |..
ldntslyGdilvtlkgrevkdryaistlllkrv...dkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 866-1081 | 3.8e-24 | 79.8 | In-house | 29-220 (281) | alignment | ||
Range on Protein: 866-1081
Range on HMM: 29-220/281.0
CAAA--ERNVDRNRYRDILPYDRTRVHMQV-LPGYGSTdDYINACHVRSLTSGcPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRY
|.. | .||| .| | .||...| .| || ||| | ..|| .. .||||. | |||.|. |. . |||. .. | | || |
ctvfnqpvnnkknrylnipcldisrvqlkvkmpnknst.dyihanyirspflk.rgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaey
WPARCGETVSHPEtalglaldVTLKEERETgpwIERDLIVETLRPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQhhdavqRqSqtagepqS
.| . . . .... | | ... |. | . | . .. . ||| || | | .|. | .. | | .
fprnahcclqfdk........lsvsyedst...vnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira......r.s.......t
PLVVHCSAGVGRTGTFCCV
| |.||||||||.||. .|
ppvihcsagvgrsgtlmav
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 1004-1146 | 8.5e-24 | 79.3 | In-house | 35-138 (145) | alignment | ||
Range on Protein: 1004-1146
Range on HMM: 35-138/145.0
TLRPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAvqrqsqtagepQSPLVVHCSAGVGRTGTFCCVYGVVAalpyvgnglpllaares
.| .. . .|.. |..|..||||||| ..|..|||| ........ | .||||||||||||... | .
nltselellerlgiqylylpwpDhgvpdllellleflefieealke...........ggpvlVHCsaGvgRtgtlvaaylmll.................
gaqrptresqgGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLA
.... ... ..|. |...|....|..|.|..
...........lgvsleealelvrsqrpgavpnpgqlrflyef
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 857-1081 | 2.2e-23 | 77.3 | In-house | 37-243 (310) | alignment | ||
Range on Protein: 857-1081
Range on HMM: 37-243/310.0
DAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVlpGYGSTDDYINACHVRSLTSgCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGR
|| . . | .... .||| |.. | .||.... .||| | .|.. |.|.||| | |||.|. |.|. |... . | ||
dakqdssltyeaykkymhknrysdvvcldtsrvklki..dksryedyihanyvktnyl.rstficsqgplqhtiidfwrmifqeraesilllckvgeegr
PKCDRYWPARcGETVSHP---ETALGLALDVtlKEERE-TGPWIERDLIVEtLRPDHTKMVRhVKQFHYTSWPDHGVPAspetflEfllavkQHHDAVQR
||| |||. | | .. | |. . . | . . .. .. |. .| | .| |. .. ||| ||| | . | ||
pkcvgywpsl.gvtetygcirvtnlsessee..feicnlavtfvpdnvpvd.eqpanlkelr.vslikwpnwpdrgvpd......e......kchtvpqr
QsqTAGEPQSPLVVHCSAGVGRTGTFCCV
| . | |||||||..|... . .
l..laqvrhgpcvvhcsagkdrlyvvval
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 841-1085 | 4e-23 | 76.8 | In-house | 3-216 (267) | alignment | ||
Range on Protein: 841-1085
Range on HMM: 3-216/267.0
DGKSGFDKEFALLEMEDAaHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSGCpDFVCAQGPKHSTSGDFWKMVVQQ
| . ..||| |.. . |. || | .|||. | |||| ||| .. ....|||| .| . . |. |.| . | .||.... .|
deeceiekefelikkisd.tsstisqsiaeknqernrlddnlpyddtrvilr.....tkeeeyinasyvegyktkn.afivtqdplkntitdfltvihdq
RSRVIVMVTNLeerGRPKCDRYWPARCGETVSHPEtalgLALDVTLKEEREtgpwiERDLIVETLRPdHTKMVRHVKQFHYTSWpdhGVPASPETFLEFL
. |||..|. . . ..|| . |.. . . |... .|..| . . ..|. |. . . . | ..| | . . . .|. |
kvpvivlltkv...ftdnirlfwPPkmgqakkyqd....ltvehslekeen.....dyqiitlelkf.knesahnvtlyyykkw...nintnnkpylkpl
LAVKQHHdavqrQSQtAGepQSPLVVHCSAGVGRTGTFCCVYGVV
... . | . | . ||||.||.||||.||| .. .
fgilakn.....qle.ng..nrPlvvacsdGvGrsGtflvidsql
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 863-1088 | 8.6e-23 | 75.5 | In-house | 34-236 (312) | alignment | ||
Range on Protein: 863-1088
Range on HMM: 34-236/312.0
DTSCAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSgcPD-FVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDR
|. |.| . | ||| .| .|| | . | . || | |. | |. |||.||| ..|. ||.... | |.... . | | || .
dsectaflkfkdlnrypniqcwdrgrftla.....gdenfyihanfvkictk..perfvctqgplentcthfwqlalslgstsiillcgfvedgsekcak
YWPARCGeTVSHPETALglalDVTLKEERETGPWIERDLIVETLR--PDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHhdavqrqsqtage
| | | . . | | | . |. | ..... ..||||||.| | .| | .| |||.
yisdivg.fvdledhrv....yteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkd.............
pQSPLVVHCSAGVGRTGTFCCVYGVVAAL
. |.. |||||||||||.. . ..|||
.kkpviahcsagvgrtgtlaliesmiaal
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 853-965 | 1.2e-22 | 75.1 | In-house | 28-152 (350) | alignment | ||
Range on Protein: 853-965
Range on HMM: 28-152/350.0
LEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQ-------VLPGYGSTDDYINACHVRSL---TSGCPDF--VCAQGPKHSTSGDFWKMVVQQ
|| .. . | . . .|||..||||...||... ||.||||| ... . ||| . .|.| || ||.|....
LesdsespsnDvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvilln
RSRVIVMVTNLEERGRPKCDRYWPA
.||...|.. | .. ||.|||.
kvkvilsltsdvelnlekcyrYWqe
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 1007-1145 | 3e-22 | 74.3 | In-house | 40-139 (144) | alignment | ||
Range on Protein: 1007-1145
Range on HMM: 40-139/144.0
PDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDavqrqsqtagePQSPLVVHCSAGVGRTGTFCCVYGVVaalpyvgnglpllaaresgaq
... . |.. |.....||||||| ..| .|||| ....... . | .||||||||||||... | ..
yepefleregiqylhlpwpDhgvpdllellleflefieeale...........eggpvlVHCsaGvgRtgtlvaaylmk.....................
rptresQ-GgkLDIMNIVSRMREDRRFMVQTVDQYKFCYL
| |.. ... ..|. | ..|.. .|..|...
......klg..lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 866-1081 | 2.2e-21 | 71.1 | In-house | 29-223 (285) | alignment | ||
Range on Protein: 866-1081
Range on HMM: 29-223/285.0
CAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPA
.| | | | ||| |. . ||| .. ||| | .| .. .||| | |||.|. |.. ..|. | | | || |.|
ytayeanpdlnryadvrcieetrvvlk.....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyype
RCGETVSHPETALGLAldvTLKEERETGPWIERDLIVETlrPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQhhdaVQRQsqtagepQSPLV
. || | . . |. ||| .| .. ...| | . .... . |||. | ..|. ||. |. . . |..
klgevvkfgkyeitlt...eckeeaiagtilnaltvint..edasseplymnhvqvpwwpdqlapedarpmielykwvkk....vnpk.......ekpic
VHCSAGVGRTGTFCCV
|||||||||| || .
vhcsagvgrtatfvgi
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1016-1148 | 6.8e-19 | 62.8 | In-house | 217-341 (350) | alignment | ||
Range on Protein: 1016-1148
Range on HMM: 217-341/350.0
VKQFHYTSWPDHGVPASPETFLEFLLaVKQH-HDAVQRQSQTAGEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPYvgngLPLLAARESGAQRPTResqg
| |... |.| .. || .|. | ||.. | .| . .||..||||||||||||.. . .. . | | . .....
vyqlqvknWkDlslllnPesilqale.vkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfei....lenltkesrkldvaak....
GKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
. | || ..|. | |||..||. |.| | |
trDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 913-1080 | 2.1e-17 | 57.8 | In-house | 85-233 (301) | alignment | ||
Range on Protein: 913-1080
Range on HMM: 85-233/301.0
TSGCP-DFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalgLALDVTLKEERETGPWIERDLIVETLRPDHtk
||| | |...||| ..|| ||| |.|| |||... |. ||. | | . .|.. . .. || ..| | || .
tsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigr....fkikiknkelilnkkiskrtlevedstgkf..
MVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQhhdavqrqSqtagepQSPLVVHCSAGVGRTGTFCC
| | . |..|.|.||| | ... ||. | . |.|||||||.||. .|
atrtvthyqysewtdrgvPkshaelfdlmelvkk........s......ekPivvhcsaGiGrsvafig
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 924-1083 | 4.2e-15 | 50.0 | In-house | 98-244 (302) | alignment | ||
Range on Protein: 924-1083
Range on HMM: 98-244/302.0
GPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPETALG-LALDVTLKEERETGPWIERDLIVETLRPDHtKMVRHVKQFHYT
||.|| .| .. | . ..| .... | . || |. . |... . .. . .. |.| . . .. . . |. . |. ....
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkk.kvkktvdilafs
SWPDHGVPASPETFLEFLLAVKQHHDAVqrqsqtagepqsplVVHCSAGVGRTGTFCCV-YG
.||||| |. ..| |. | . . .| .||||||||||||. . ||
awpdhGapkeaytaldilkfcesykknv..............lvhcsaGvGrtGtlvaikyG
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 930-1150 | 4.9e-15 | 50.3 | In-house | 41-220 (255) | alignment | ||
Range on Protein: 930-1150
Range on HMM: 41-220/255.0
SGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalglaLDVTLKEeRETGPWIERDLIVETLRPdhTKMVRHVKQFHYTSWPDHGV
|....||... |.||.....| |. ||..|.| | . ..|| . . . . |. || | . || ..|. |...
vdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklklad......vnvtttk.ssadvvlrtleitstlge..kkkthtvkhysykGWiekna
PASPETFLEFLLAVkqhhdavqRQSQtagepqsPLVVHCSAGVGRTGTFCcvygvvaalpyvgnglpllaARESGAQ---RPTRESQGGKLDIMNIVSRM
| .. |. | .| |.|. ..|||||.|.||. .| |. | | .... ..|| .... .
Pelareilnilkvv........rdsk.......svvvhCstGiGrsaafv....................laelvyqkmirsldttetveldylslleel
REDRRFMVQTVDQYKFCYLASLEA
|. |. ..| | |. | |.
rskrkraihtPlqlafsilmvldl
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 856-971 | 9.4e-15 | 49.1 | In-house | 24-135 (307) | alignment | ||
Range on Protein: 856-971
Range on HMM: 24-135/307.0
EDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPGYgSTDDYINACHVRSlTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERg
|..... ||.. | .. | . . | .||.... | .||.| | .|. .|..|| | | |||.|| |.. . |||.| |
eesvdeislttaasdnnlekarskrvhckdssrvklelrrGq.ylddfihanrvkG.kpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes.
rPKCDRYWPARCGETV
.|. ||| ...
.erceyywpkaesdsl
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 853-964 | 1.2e-12 | 41.9 | In-house | 29-154 (349) | alignment | ||
Range on Protein: 853-964
Range on HMM: 29-154/349.0
LEMEDAAHNRDTSCAAAERNVDRNRYRDILPYDRTRVHMQVLPG-------------YGSTDDYINACHVrSLTSGCPD--FVCAQGPKHSTSGDFWKMV
|| .| .. | . . .|||.|||||. .|| .. . | |||||| .. .|| .. ... | | || ||.|..
lesdddseiddvilseGvelfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanyl.kltrisvekkyiatqaPlPstvddfykvi
VQQRSRVIVMVTNLEERGRPKCDRYWP
. .. .... ... .| . |||.||
llngvklvlsLnddkelslekcdiywq
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 855-1039 | 2.8e-12 | 40.7 | In-house | 35-203 (332) | alignment | ||
Range on Protein: 855-1039
Range on HMM: 35-203/332.0
MEDAAHNRDTSCAAAERNVDRNrYRDILPYDRTRVHMqvLPGYGSTDDYINACHVrSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEER
..| . . | .| .|.|| .|.|||| |.. . . |||| . .. .. . .... ||.||..|.| ||.. . |
lddyqrllsisetarleavnrn.vvkivpydrylvrl..tssqlnrlGyinasla.efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvel
GRPKCDRYWPARCGETVSHpetalGlALDVTLKEERETGPWIERDLIVETlrPDHTKMVRHVKQFhytSWPDHGVPASpETFLEF
. | |.|.| . | ... | |||. || . . | |... . |. | | | | | . .| | || .
kleksdkyfpdktreelkf.....G.ildverkefvkrniletrllelsk..Gnethrvlhykvf...Gwtettlpky.edflal
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1016-1148 | 4.8e-12 | 39.9 | In-house | 220-341 (349) | alignment | ||
Range on Protein: 1016-1148
Range on HMM: 220-341/349.0
VKQFHYTSWPDHGVPASPETFLEFLLaVKQH-HDAVQRQSQTAGEPQSPLVVHCSAGVGRTGTFCCVYGVVAalpyvgnglpLLAARESGAQRPTRESQG
. |. . |.| .. | ..|. | ||.. | . . |.|.|||||| ||||... . ... .| . . . ...
llqlqvknwldlslllnPisilqale.vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldllls..........ileplqnesnkiklqall
gKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASL
| |. || .| | ||| . |. ..| | |
.kDlisiivnelrkqrismvqnlaqfiaiyealL
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 918-1081 | 5.2e-12 | 40.3 | In-house | 5-154 (198) | alignment | ||
Range on Protein: 918-1081
Range on HMM: 5-154/198.0
DFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPETALGlALDVTLKEERETGPWIerdLIVETLRPDHTkmvRHVK
....| | . | |||.|| . | |||| . . |||. | . .. . .| | . | | .| | | | .
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvt.tktittkpdytitali...ltnnttappst...reis
QFHYTSWPDHGVPASpETFLEFLLAVKQhhdAVQRQSQtagEPQSPLVVHCSAGVGRTGTFCCV
.. .||| .. | |. |..| .. .. | | ..|..|||| | | || | ..
hyqftswkekttpnv.alfvgfvvasre...vskkyeq...ekdapvivhcsdgqgftgvfval
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 918-1081 | 5.9e-12 | 40.2 | In-house | 6-155 (199) | alignment | ||
Range on Protein: 918-1081
Range on HMM: 6-155/199.0
DFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPETALGlALDVTLKEERETGPWIerdLIVETLRPDHTkmvRHVK
....| | . | |||.|| . | |||| . . |||. | . .. . .| | . | | .| | | | .
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvt.tktittkpdytitali...ltnnttappst...reis
QFHYTSWPDHGVPASpETFLEFLLAVKQhhdAVQRQSQtagEPQSPLVVHCSAGVGRTGTFCCV
.. .||| .. | |. |..| .. .. | | ..|..|||| | | || | ..
hyqftswkekttpnv.alfvgfvvasre...vskkyeq...ekdapvivhcsdgqgftgvfval
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 932-1148 | 9.4e-12 | 39.4 | In-house | 49-224 (263) | alignment | ||
Range on Protein: 932-1148
Range on HMM: 49-224/263.0
DFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPARCGETVSHPEtalglaLDVTLKEEREtGPWIERDLIVETLRPdhTKMVRHVKQFHYTSWPDHGVPA
|....||... |.||... .| |. ||..|.| | . ..|. . . . . ...|| | .. ||.. |. |... |
kfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklan......vnvcttkvqs.dvllktlellstlge..KkkthtvkhysykgWiekndpe
SPETFLEFLlavKqhhdaVQRQSQtagepqsPLVVHCSAGVGRTGTfccvygvvaalpyvgnglplLAARESGAQ---RPTRESQGGKLDIMNIVSRMRE
.. |. | | | |.|. .||||||.|.||. . |. | | .... ..|| .... .|.
lareilnil...k.....varnsk.......slvvhcstGiGrsaa....................fsvaElvyqkmirsldttstveldylsLleelrs
DRRFMVQTVDQYKFCYLASL
|. ..| | | | |
srkraihtPmqLafsilmvL
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1013-1150 | 9.8e-12 | 38.9 | In-house | 88-193 (440) | alignment | ||
Range on Protein: 1013-1150
Range on HMM: 88-193/440.0
VRHVKQFHYTSWPDHGVPASPETFLEFLlavkQhhDaVQRQSQTAGepQSPLVVHCSAGVGRTGTFCCVYGVVaalpyvgnglpllaaREsgAQRptreS
| .||.|| .|||.||| |... | | |. . || ..||.||||||.|||| .| .. || |.| |
srtlkqyhyqgwpdkgvpkfagpvlkmi....q..d.vnesqekag..ngpllvhcsagagrtgviiavdsil...............re..akr....s
qgGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEA
..||..... ||..| |||| .|| | . | ||.
..dqidifsfinsmrnnrpqmvqtpeqyafvheavleg
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 1113-1168 | 7.2e-11 | 36.4 | In-house | 243-299 (564) | alignment | ||
Range on Protein: 1113-1168
Range on HMM: 243-299/564.0
QGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARRYNDKYG-QQFRRRQRT
. ...||...|...|..| .|||| .|| |.. | ||| .|.. ...... .
eektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqk
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 893-1079 | 1.1e-10 | 36.2 | In-house | 36-209 (290) | alignment | ||
Range on Protein: 893-1079
Range on HMM: 36-209/290.0
VLPGYGS--TDDYINACHVRsLTSGCpDFVCAQGPKH-------STSGDFWKMVVQQRSRVIVMVTNLEERGRP----KCDRYWPARCGETVSHPetalG
|| |||. .|||| | .| .| .. | |.. || .|| |. | ... .||. . ||. . | .| | . || . |
vLkgygkrfnddyiHAnrvt.cpngl.rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk....g
LALDVtlKEERETGPWIERDLIVETlRPDHTKMVRHvkqFHYTSWPDHGVPASPETFLEFLLAVKQHhdavqrqsqtagepQSPLVVHCSAGVGRTGTFC
| . |. . ..| |.|. .. | | . .| . |. .. |.|. . ||.. ..| .||| |. | ..
ltvkC..kskekeddvetRelvvkf.ddeeeftvtH...sllkgWnklnvqedtktllsliqkvkas..............ktpvivHcvdGiSrsAala
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 999-1082 | 1.6e-10 | 36.5 | In-house | 62-136 (194) | alignment | ||
Range on Protein: 999-1082
Range on HMM: 62-136/194.0
DLIVETLRPDHTKMVRHVKQFHYTSWPDHGVPASPETFLEFLLAVKQHHDAvqrqsqtagEPQSPLVVHCSAGVGRTGTFCCVY
|| .. |.... .. ... .||.|.. | |. |.|| .|...... |. .||| ||.|||||... |
dltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflne.........dpggvvaVHCkaGlgRtGtlvaaY
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 1113-1153 | 5.9e-10 | 33.7 | In-house | 252-292 (297) | alignment | ||
Range on Protein: 1113-1153
Range on HMM: 252-292/297.0
QGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARR
. |..|... |...|. | |..|| .||.||||| || | .
evgtvdvvetvkllrtqrafsiqtpeqyefcylavleyale
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 871-965 | 9e-10 | 32.6 | In-house | 95-180 (244) | alignment | ||
Range on Protein: 871-965
Range on HMM: 95-180/244.0
RNVDRNRYRDILPYDRTRVHMQVlpgYGSTDDYINACHVRSLTSgCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERgrpkcDRYWPA
| .|| ||.| || . . |||| | | ... .| | || |||||.... |.|.. .|| | |||
nnswknregaglpfdfnrvplsk...gsmgntyinasfvgclgr.taeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpd
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1113-1175 | 1.6e-09 | 32.2 | In-house | 245-308 (319) | alignment | ||
Range on Protein: 1113-1175
Range on HMM: 245-308/319.0
QGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARRYN-DKYGQQFRRRQRTLIPVIPE
. | ||. ..|||.| | .|||. .||||.| | |||. .. . |..| | ..| ...
eegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqlaekvad
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 871-1080 | 2.4e-09 | 31.2 | In-house | 46-230 (303) | alignment | ||
Range on Protein: 871-1080
Range on HMM: 46-230/303.0
RNVDRNRYRDILPYDRTRVHMqvlpgygSTDDYINACHVRSLTSGcpDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGRPKCDRYWPaRCGET
.|.|.||. |.. | ..|.. | || | .. .| . .| | |. |||.|...|. ...... | . | .| | .
knmdknrfvdvicldhskvkl.......sdssyihasyleldssk..kailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfp.rnqdf
VSHPETALGLAldvTLKEERETGPWIERdliVETLRPDHTKMVRHVkqFHYTSWPDHGVPASPETflEFLLAVKQHHDAVQRQSqtagePQSPLVVHCSA
. | .. . .|. . | . | .. . | || || .|| .|. .|. . | ... | . .| | .
lkfeersirvg...efkrvelgdgwvlk...vlsvsngdyksflhv..hhykawphnsipsdgsp..kfvkqiwqlqsvlrkys.....dstptvymsls
GVGRTGTFCC
|.||.|||.
gcgragtfal
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 834-912 | 6.5e-09 | 29.9 | In-house | 13-84 (95) | alignment | ||
Range on Protein: 834-912
Range on HMM: 13-84/95.0
HLQQAYPDGKSGFDKEFALLEMEDAAHNrdtSCAAAERNVDRNRYRDILPYDRTRVHMQVlpgyGSTDDYINACHVRSL
|. . . . ||.|| . | | .. ..| |. .||. .|.||| ||| . |||||| |
hvlemhsnsdqefdnefksismtsgapy...tvgsseanipknrflnifpydatrvvltt....krdsdyinacfvdgy
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1113-1178 | 6.5e-09 | 30.3 | In-house | 242-308 (318) | alignment | ||
Range on Protein: 1113-1178
Range on HMM: 242-308/318.0
QGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARRYNDK-YGQQFRRRQRTLIPVIPEEGT
. . .|....|...|| | |||| |||.|.| . ||| .. . ...|.| | | . || ||
aealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelreqdpesgt
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 859-1079 | 4.1e-08 | 27.0 | In-house | 39-236 (302) | alignment | ||
Range on Protein: 859-1079
Range on HMM: 39-236/302.0
AHNRDTsCAAAERNVDRNRYRDILPYDRTRVHMQvlpgyGSTDDYINACHVRSLTSGcPDFVCAQGPKHSTS---GDFWKMVVQQRSRVIVMVTNLEERG
. . | | .|...|. |. .| ..| .. .. |.|.|| .| . . . || || ... .||.|| |.. .|.. ||
kvdlek.Ckafkknlkknqsedvpildsnlvkle.....aepdsyvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelk
RpKCDRYWPARCGETVSHPETALGLALdVTLKEERETgpwierDLIVETLRPDHTKMVrHVKQFHYTSWPDHGVPASPETFLEFLLAVkqhhdaVQRQSQ
. . ..| . |. . . . . | .|| .| ...| | . . | .. . | |... || . . . | .....
k.tlselfpkksgdykeygkmfvNnrk.Vekaeeekt......ryviEvlPegcsnsv.lanvyvltnWkqkkvpvkyaeliktaakv......fakkik
TagepQSPLVVHCSAGVGRTGTFC
. ....|. |.|| |.|
a....dentvivSknGaGRagafl
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 867-947 | 7.1e-08 | 26.3 | In-house | 32-115 (347) | alignment | ||
Range on Protein: 867-947
Range on HMM: 32-115/347.0
AAAERNVDRNRYRDILPYDRTRVHMQVLP-GYGST---DDYINACHVRSLtSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVM
. |.....|| .| | ||| . . . . |||| |.. ... .| | .| |||||| . .|
vewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfd.naskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1112-1152 | 7.6e-08 | 26.8 | In-house | 237-277 (281) | alignment | ||
Range on Protein: 1112-1152
Range on HMM: 237-277/281.0
SQGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAAR
.. .||. ..| .|..| .||||| ||.| |.| |.|
aeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1116-1156 | 8.1e-08 | 26.8 | In-house | 255-295 (298) | alignment | ||
Range on Protein: 1116-1156
Range on HMM: 255-295/298.0
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARRYND
..|....| ..|..| .||| .||.|.| | ||| .||
vvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnd
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1116-1151 | 1.2e-07 | 26.2 | In-house | 249-284 (297) | alignment | ||
Range on Protein: 1116-1151
Range on HMM: 249-284/297.0
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAA
..||...|...|..| ..||| .|||| | | |||
evdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
| DUF2959 | Protein of unknown function (DUF2959) | 483-546 | 3.5e-07 | 16.5 | Pfam-A | 28-91 (201) | alignment | ||
Range on Protein: 483-546
Range on HMM: 28-91/201.0
QRLEQAQEHLAGFQERFEAAAAKFESARKMASDRLRQEHDDMKSSLQQAQQAVRLARDKLEAIE
.|.|.|.| .|.|. | .|.| .. . | ...............| . .......|
drvedaresqeeakeqfksaleqfkslvnfdggdlekkynelndeyeesesaaeevseridkve
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 1115-1149 | 3.5e-07 | 24.4 | In-house | 259-293 (330) | alignment | ||
Range on Protein: 1115-1149
Range on HMM: 259-293/330.0
GKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLE
.|.|. ..|.|.| | |||| ||.|.| . ||
rkvdvfefvkrlrlqrpqmvqtdeqyefiykvlle
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1116-1151 | 6.6e-07 | 23.7 | In-house | 253-288 (325) | alignment | ||
Range on Protein: 1116-1151
Range on HMM: 253-288/325.0
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAA
..||.. | ..|.|| ||.||||| ..| | ||
rvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 1115-1151 | 1.2e-06 | 22.6 | In-house | 241-277 (314) | alignment | ||
Range on Protein: 1115-1151
Range on HMM: 241-277/314.0
GKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAA
| .|. |.| .|. . ||.| .||||.| . |||.
gvvdvfnavktlrsrkvnmveteeqykfiydvileac
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1116-1155 | 1.4e-06 | 22.7 | In-house | 207-246 (250) | alignment | ||
Range on Protein: 1116-1155
Range on HMM: 207-246/250.0
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARRYN
..|..... ..|.|| .|.. .|| |.| . |.| ..
vvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsve
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1116-1150 | 2e-06 | 22.1 | In-house | 205-239 (239) | alignment | ||
Range on Protein: 1116-1150
Range on HMM: 205-239/239.0
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEA
.||.| | .|||| .|||| .|| | .|| |||
tvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 882-965 | 3.3e-06 | 21.4 | In-house | 3-71 (130) | alignment | ||
Range on Protein: 882-965
Range on HMM: 3-71/130.0
LPYDRTRVHmqvlpgygsTDDYINACHVRSLTsGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERgrpkcDRYWPA
|... .|.. ..|||| | | ... .| | || |||||.... |.|.. .|| | |||
lefevsrlq.........gntyinasfvGllg.rtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpd
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1115-1150 | 4e-06 | 20.9 | In-house | 241-276 (315) | alignment | ||
Range on Protein: 1115-1150
Range on HMM: 241-276/315.0
GKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEA
.|..|.| .|..| ..||| ..| | | | ||
rsvdvfnfvknlrakrpylvqteeeyafiydavled
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1114-1150 | 6.4e-06 | 19.5 | In-house | 239-275 (515) | alignment | ||
Range on Protein: 1114-1150
Range on HMM: 239-275/515.0
GGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEA
. .|..|.| .|..| ..||| .|| | | | ||
trmvdvfnfvtnirqkrpylvqtqeqyafiygavled
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1116-1149 | 7.6e-06 | 20.3 | In-house | 206-239 (239) | alignment | ||
Range on Protein: 1116-1149
Range on HMM: 206-239/239.0
KLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLE
.||.| | .|||| .|||| .|| | .|| ||
tvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1113-1153 | 7.8e-06 | 20.1 | In-house | 226-266 (270) | alignment | ||
Range on Protein: 1113-1153
Range on HMM: 226-266/270.0
QGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAARR
. .|.|...|....|.|| .||...||.| | | .| |.|
etkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||