Gene DSP14 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP14
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP008_AA protein Get Run
NvecP008_AA_16-161 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP14_pd Subfamily DSP14 15-169 5.6e-69 225.1 In-house 3-156 (157) alignment
Range on Protein: 15-169
Range on HMM: 3-156/157.0
PLTAMARITEWLFLSsCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLV
.|.|...||..|||| ...|....|| .|.|||.||.|.|.|....|........|.||| .|.  .||.|.||||.|.. |||.||||.|||||||||.
elaalsqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslc

IAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGKNSVQMVDTK
.||||||..|.||.|.|||...||.||||.||||.||||||||.||.||.|||..
laylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgkssvkmvdsp

subfamily_DSP10_pd Subfamily DSP10 18-160 3.4e-42 138.0 In-house 13-156 (159) alignment
Range on Protein: 18-160
Range on HMM: 13-156/159.0
AMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYK-KVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIA
 ....  .||| | . |.|...| . .|| |.| | . | . .. ..|. ||.|.|.  ...   |.   . || .|. | .||||| ||.||||..|||
pasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGK
||||...|.|.||.|.|..||| | || .|  .|...||.|  .
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks

subfamily_DSP1_pd Subfamily DSP1 16-158 1.3e-41 136.4 In-house 14-157 (163) alignment
Range on Protein: 16-158
Range on HMM: 14-157/163.0
LT-AMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLV
|   . .|...|.| |..|| . ..| ..||| ..|.. | ..   .  .. ..|..|.| . |   |. | . |..|.. .||||.|| ||.|||..|.
lydPvekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlc

IAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
.||||| .|..| .|...|...|..|.||.|| ..|..||||| 
laylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll

PTPc_motif_SM00404 19-156 4.6e-41 135.0 In-house 2-140 (140) alignment
Range on Protein: 19-156
Range on HMM: 2-140/140.0
MARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPE-QDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAY
. ||.. |.|.|.. | ...|| ..|||.|||.| | .  .  .......|...||  .|.  ..|.| | ||.... |||||||| |||||||.|.|||
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

LMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKK
||.|. |.|..| ..|...|| |.||..|...||.||||
lmryrqlslaeayefvkerRpiispnlnfvrqLieyekk

subfamily_DSP19_pd Subfamily DSP19 18-157 9e-40 130.5 In-house 11-150 (152) alignment
Range on Protein: 18-157
Range on HMM: 11-150/152.0
AMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAY
 .. ....|.|.|..|| |.. | ||.|| ..| ... |.   |...   |.. |.| ...  ... . | ||..|.  | ||||| ||||||||.||||
evgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviay

LMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
||| ..|.|..| .||...|| |.||.||.| | .||..|
lmkkeelsleealelvrearpcikPneGFikqLkeyeael

DSPc Dual specificity phosphatase, catalytic domain 26-156 3.3e-39 128.8 Pfam-A 1-133 (133) alignment
Range on Protein: 26-156
Range on HMM: 1-133/133.0
LFLSSCQVARdEKLLLEKGITLVINATIEAPE---QDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQ
|.|.|.. |  ..|| ..|||||||.| | |.   .  .. ...||.|.|.  .||  ....... ||.... |.|||||| ||.||||.|.||||||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

RLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKK
.|.|..| ..|...|. |.||.||...|..||.|
nlslneAyefvkerrskispnagflrqLleyerk

DSPc Dual specificity phosphatase, catalytic domain 26-156 3.3e-39 128.8 In-house 1-133 (133) alignment
Range on Protein: 26-156
Range on HMM: 1-133/133.0
LFLSSCQVARdEKLLLEKGITLVINATIEAPE---QDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQ
|.|.|.. |  ..|| ..|||||||.| | |.   .  .. ...||.|.|.  .||  ....... ||.... |.|||||| ||.||||.|.||||||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

RLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKK
.|.|..| ..|...|. |.||.||...|..||.|
nlslneAyefvkerrskispnagflrqLleyerk

subfamily_DSP8_pd Subfamily DSP8 18-158 2.2e-37 122.1 In-house 14-155 (159) alignment
Range on Protein: 18-158
Range on HMM: 14-155/159.0
AMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDY-KKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIA
 . ||.. |.| | ... .|.|| ..||. |.||  . |...  |..| .|. |.|.  .|.  .||.  . |. ...  |.||||. || ||||...||
gptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaia

YLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
|.||. ...| .|.. |..|||.| ||  | . |..|||.| 
yimktlemsldeayrfvkekrptispnlnflgqLleyekelk

0044763 (Phosphotyrosine protein) phosphatases II 15-162 4.3e-37 122.8 In-house 19-175 (178) alignment
Range on Protein: 15-162
Range on HMM: 19-175/178.0
PLTAMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQ-------DYKK--VKHIRIKVNDNPGNKIGIFFDMVSDKIESVR-RVGGKVLVHCI
. . . .|.. |.|.|.  |.| .|| | |||...| | | .         ....  .....| . |..   .  .|. . . ||... . ||.||||| 
dyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHCs

AGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPlIRPNTGFWKELIDYEKKLFGKNS
|||.||..||.|||||...|.| .| .||. .|| | || |... |...|..|.....
aGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkesd

subfamily_DSP12_pd Subfamily DSP12 19-157 5.2e-33 108.6 In-house 2-143 (155) alignment
Range on Protein: 19-157
Range on HMM: 2-143/155.0
MARITEWLFLSSCQVARDEKLLLEKGITLVINATIEA---PEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVI
. ||.. |.|.. . . .|.|| | .|| |.  . |.    ... .||..  |.. |.| . |  ..| . | ||. .  .|.||||| ||||||...||
vsrilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtivi

AYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
|||||...|.| .|.|||..|.| |.||.|| . |  .||  
AYlmkkeklslekAlklvkekkpeiepNegFleQLklfekmg

0048076 (Phosphotyrosine protein) phosphatases II 19-158 1e-32 108.1 In-house 4-143 (145) alignment
Range on Protein: 19-158
Range on HMM: 4-143/145.0
MARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYL
...|.. |.|.|. .|.| .|| . |||.|.| | | .    . ...... . |..   .  ... . . ||.... ||.||||| |||.|...||.|||
pseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl

MKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
|......| .| .||. .|| . || |... |...|..|.
mlllgvsleealelvrsqrpgavpnpgqlrflyefelell

subfamily_DSP3_pd Subfamily DSP3 15-158 1.6e-32 106.4 In-house 7-158 (162) alignment
Range on Protein: 15-158
Range on HMM: 7-158/162.0
PLTAMARITEWLFLSSCQVARDEKLLLEKGITLVINATIE------APEQDYK--KVKHIRIKVNDNPGNKIGIFFDMVSDKIES-VRRVGGKVLVHCIA
. ...  ... |...  .||.|.. | . ||| |.||.        . .. ||  ..|.. ..|.|.|  ..  .|. ... |.. . .  ||||||| .
lskevdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvv

GVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPlIRPNTGFWKELIDYEKKLF
|||||| ||.|||| .....| .| . |..||  |.||.|| | |......| 
GvsRsatlvlayLmirrkmtlveairtvrkkRe.ilPneGFlkqLaeldeelk

subfamily_DSP6_pd Subfamily DSP6 15-157 1.9e-32 106.0 In-house 10-154 (158) alignment
Range on Protein: 15-157
Range on HMM: 10-154/158.0
PLTAMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQ--DYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSAS
  .. ..|.. |.| | . | . ..| . .|  |.| | . |..  . ...|. .| ..|.  ...  ||    . |.  |.   ||||||.||.|||  
eaefpveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvt

LVIAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
...|||||.. | | ||..||..... | ||  | . |.|.|..|
vtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldfersl

0048179 (Phosphotyrosine protein) phosphatases II 19-157 1.9e-32 107.3 In-house 4-144 (144) alignment
Range on Protein: 19-157
Range on HMM: 4-144/144.0
MARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKV--KHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIA
...|.. |.|.|. .|.| .|| . |||.||| | | . .....   ..... . |..   .  ... . . ||.... ||.||||| |||.|...||.|
pseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaa

YLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
||||...|.| .| .||. .|| . || |... |..|||.|
ylmkklglsleealalvrsrrpgavpnpgqlrfLleyekll

subfamily_LRR-DSP_pd Subfamily LRR-DSP 21-161 3.1e-32 105.7 In-house 122-262 (263) alignment
Range on Protein: 21-161
Range on HMM: 122-262/263.0
RITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRI-KVNDNPGNKIGIFFDMVSDKIESVRRVGGkVLVHCIAGVSRSASLVIAYLM
 | . ||| . . | .. .| ..|.| .. |  .      |  |.. | ...| .  .|  .|. .   ||. |. || ||||| ||||||..|||.|||
eiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvisylm

KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGKN
|.|||....|  ||. ||| |.||.|| . |  ||||||  |
kkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklfctn

subfamily_DSP15_pd Subfamily DSP15 19-157 5.1e-32 105.0 In-house 2-139 (151) alignment
Range on Protein: 19-157
Range on HMM: 2-139/151.0
MARITEWLFLSSCQVARDEKLLLEKGITLVINATiEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYL
. .. . |.|.  ....||.|| || || ...   . ...  |....  |...| |. |.  ||.   . | . |  ...|||||.||||||. ||.|||
iskvlpglylgnfrdskdeelLkeknithilsvh.dnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYl

MKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
|    || ||| . .. .| .  ||.|| . | .|||. 
mtvtelnwrdalevikaaRsvanPnfGfkrqlkeyektk

0041856 (Phosphotyrosine protein) phosphatases II 19-161 1.9e-31 104.4 In-house 19-176 (182) alignment
Range on Protein: 19-161
Range on HMM: 19-176/182.0
MARITEWLFLSSCQV--------------ARDEKLLLEKGITLVINATIEAPEQDYKKV---KHIRIKVNDNPGNKigifFDMVSDKIESVRRVGGKVLV
. .|.. |.|.|.                |.. ..| | |||...|.| |    .. .    ..... . |..       .|.. | || |.. ||.|||
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvlV

HCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRP--LIRPNTGFWKELIDYEKKLFGKN
|| |||.|...||.|||||.....|..| |||. .||   |.|| .|.  |. .|..|..|.
HCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllkkt

subfamily_Slingshot_pd Subfamily Slingshot 18-158 3.6e-31 101.8 In-house 18-158 (169) alignment
Range on Protein: 18-158
Range on HMM: 18-158/169.0
AMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAY
. ..| ....| |   | . . | |.|.. ..| | |  .   .|.....|.| |.. ...  ...   . || ... | ||||||  ||||||| ||||
saskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviay

LMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
 ||  .|.| .|.. |...| .|.||.||.| |  ||  | 
amkeyglsleealeyvkerrsvikPnkgflkqleeyeGile

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 24-155 3.1e-30 98.6 In-house 13-145 (148) alignment
Range on Protein: 24-155
Range on HMM: 13-145/148.0
EWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQ-DYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQ
 .||| | . | | . | . |.| ..||| | .   | . .... ....|.| . .  .|. . . .. ..  |..||||.  |||||. |....|....
afLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfk

RLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEK
|  |..|  ||..||. ..|| || | | ..|.
rvslkealalvkskrryvdpnlgfLkqLaeleq

subfamily_MKPLT_pd Subfamily MKPLT 24-160 2.2e-28 92.8 In-house 27-163 (164) alignment
Range on Protein: 24-160
Range on HMM: 27-163/164.0
EWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQR
. |.|   . |..||.| .  || ..| . |  ..  | |.. ..||.|.. .... |.. ... . .    ||.|||||  |.|||.|  .|.|.|...
dtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskg

LNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGK
  |..|.. ....| ...|| || |.|  .|. ..||
wtlkeayeylkerrsivapnrGflkqlakfeelilGk

subfamily_MKPLV_pd Subfamily MKPLV 24-160 2.2e-28 92.8 In-house 27-163 (164) alignment
Range on Protein: 24-160
Range on HMM: 27-163/164.0
EWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQR
. |.|   . |..||.| .  || ..| . |  ..  | |.. ..||.|.. .... |.. ... . .    ||.|||||  |.|||.|  .|.|.|...
dtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskg

LNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGK
  |..|.. ....| ...|| || |.|  .|. ..||
wtlkeayeylkerrsivapnrGflkqlakfeelilGk

0049772 (Phosphotyrosine protein) phosphatases II 23-159 2.5e-28 95.1 In-house 155-275 (314) alignment
Range on Protein: 23-159
Range on HMM: 155-275/314.0
TewlflsSCQVARDEKLLLekgitlvinaTIEAPEQDYKK--VKHIRIKVNDnPGNKIGIFFDMVSDKIESVrRVGGKVLVHCIAGVSRSAS-LVIAYLM
.      .  .|.| .||           ..  . .....  .|..|| | | ..  .  .|| . . ||.. . ||.||||| ||..|... .|.||||
g......neptaadlellk..........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylm

KYQRLNLRDAHKLVQDKRPlIRPNTGFWKELIDYEKKLFG
|.....|..| . |. ||| |.|| ||.. |..||..|  
kllgvsleealedvrlkRp.inpnpgfieqleqyefilea

0043147 (Phosphotyrosine protein) phosphatases II 21-158 1.1e-27 92.2 In-house 21-161 (172) alignment
Range on Protein: 21-158
Range on HMM: 21-161/172.0
RITEWLFLSSCQVARDEKLLLEKGITLVINATiE----APEQDYKKVKHIRIKVNDNPGNkIGIFFDMVSDKIES--VRRVGGKVLVHCIAGVSRSASLV
|.  .... .. .| . ..| |.|||...|.| |    ..      ...... . |..   .  ... . . |..  ... ||.||||| |||.|.. ||
rfiatqgplrntladfwrmlkelgithivnlt.ellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlv

IAYLMKyQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
.||||. ..|.| .| .||..||| . .| .... | ..||.|.
aaylml.lglsleeavalvrekRpgavqnpsqyrflyyfeklll

0049260 (Phosphotyrosine protein) phosphatases II 21-157 3.9e-27 90.2 In-house 10-149 (152) alignment
Range on Protein: 21-157
Range on HMM: 10-149/152.0
RITEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKKV---KHIRIKVNDNPGNKIGIFFDMVSDKIES-VRRVGGKVLVHCIAGVSRSASLVIA
... .... .  .| . ..| | ||| ... | . .   .|     ..... . |..  .. ...... . ||   .. ||.||||| |||.|.. ||.|
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaa

YLMKyQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
|||. ....| .| .||. ||| . || |... | ..||.|
ylml.lgvsleeavalvrekRpgavpnpgqlrflyefekll

0045098 (Phosphotyrosine protein) phosphatases II 18-159 5.9e-27 90.2 In-house 21-273 (278) alignment
Range on Protein: 18-159
Range on HMM: 21-273/278.0
AMARITEWLFLSSCQ-----------------------------------------VARDEKLLLEKGITLVINAT------------------------
 . .||..|.|..                                           || . ..| | ||| ....|                        
ipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygd

-----------------------I----EAPEQdyKKVKHI---RIKVNDNPGNKIGIFFDMVSDKIESVRR--------------VGGKVLVHCIAGVS
                       .    |  |.   .|.|.    .  .. | . |  .|. . . |.....               ||.||||| |||.
ftvtllseevlddytlrtllvtnltveredles..rgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvg

RSASLVIAYLMKYQ---RLNLRDAHKLVQDKRPL-IRPNTGFWKELIDYEKKLFG
|.. ||.||||...   ...| .| | .. .||  . .| .... |.... .|. 
RtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelll

PTEN_1 33-158 1.6e-26 88.3 In-house 56-192 (196) alignment
Range on Protein: 33-158
Range on HMM: 56-192/196.0
VARDEKLLLEKGITLVINATIEAPE--QDY-------KKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRR--VGGKVLVHCIAGVSRSASLVIAYLMKY
||.| . | |.|||||.| . | ..  ..|       ..|..... ..| .   .  .||.. . ||....   |..||||| ||..||. .|.||||..
vaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmyk

QRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
..|. ..| .||..||| ..||......|. |...|.
gkltadeAlelvrekRppgapnspsqerlleyfaell

0051082 (Phosphotyrosine protein) phosphatases II 14-154 2.6e-26 87.4 In-house 3-150 (151) alignment
Range on Protein: 14-154
Range on HMM: 3-150/151.0
SPLTAMARITEWLFLSSCQVARDEKLLLEKGITLVINATIEA---PEQDYKK---VKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRV-GGKVLVHCIAG
|... . ..|. |..|..  |.. .|| | ||. ..| . |     . .| .   .....| . |.|  .. ..|| | . .| ...  .|.||||| ||
sdyinfsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaG

VSRSASLVIAYLMKyQRLNLRDAHKLVQDKRP-LIRPNTGFWKELIDYE
..|.. ||..|||. ....| .| . .. ||| ...||..|...|....
kgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfall

subfamily_STYX_pd Subfamily STYX 18-165 3.2e-26 85.4 In-house 11-165 (166) alignment
Range on Protein: 18-165
Range on HMM: 11-165/166.0
AMARITEWLFLSSCQVARDEKL--LLEKGITLVI--NATIEA----PEQdYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSR
 |  |   |||     |   ||  | ..||| ..    .|||    |.   .. ... . | ||. ..|  .. .| . |..  . |||||||  ||.||
emqeilpglflgpysaamksklevlkkhgithivcirqnieanlikpnf.pdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisr

SASLVIAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGKNSVQM
||.|||||.|.   |. |.|.. ||..|  | || || ..| .||   . | ....
saalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylakltikl

0040439 (Phosphotyrosine protein) phosphatases II 34-159 2.4e-25 85.0 In-house 68-247 (249) alignment
Range on Protein: 34-159
Range on HMM: 68-247/249.0
ARDEKLLLEKGITLVINATIEAPE-------------------------------------------QDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIE
. . ..| | ||| ....| . .                                            .| ....   | . | |  ..  .|. . | ||
edfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfie

SVRR------VGGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFG
 ||        ||.||||| |||.|.. ...||||     |.....| .| ||....|| . .| .... |......|. 
avrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll

0046846 (Phosphotyrosine protein) phosphatases II 16-159 3.2e-25 84.3 In-house 9-174 (176) alignment
Range on Protein: 16-159
Range on HMM: 9-174/176.0
LTAMARITEWLFLSSCQ----------VARDEKLLLEKGITLVINATIEA-----------PEQDYKKVKHIRIKVNDNPGNKIgIFFDMVSDKIESVRR
   . .|.. |.|.|.           .| . ..|.| |||.|.| | |            ||    ....... . |.    .   .. . . |.....
dldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealk

VGGKVLVHCIAGVSRSASLVIAYLMKY-QRLNLRDAHKLVQDKRP-LIRPNTGFWKELIDYEKKLFG
 ||.||||| ||..|.. ||.|||... . |.. .| .||...||  . .. .... | ..|..|..
eggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefellllk

0036282 (Phosphotyrosine protein) phosphatases II 17-157 1.3e-24 82.2 In-house 10-169 (174) alignment
Range on Protein: 17-157
Range on HMM: 10-169/174.0
TAMARITEWLFLSSCQVArDEKLLLEKGITLVINATIEAPEQ---------------DYKKVKHIRIKVNDNPGNKIGIfFDMVSDKIESVRRV--GGKV
  . .||. |.....  | . ..| | ||| |.. . | . .                   ...... . |.    . | .. . . .|...    ||.|
ldlsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpv

LVHCIAGVSRSASLVIAYLMKYQRL-NLRDAHKLVQDKR---PLIRPNTGFWKELIDYEKKL
|||| |||.|.. ||.||||... | .|.|| .||. .|   | . .. .... | ..||.|
lVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll

0045450 (Phosphotyrosine protein) phosphatases II 38-158 2.3e-24 82.1 In-house 125-304 (307) alignment
Range on Protein: 38-158
Range on HMM: 125-304/307.0
KLLLEKGITLVINATIEAPE----------------------------QDYKKVKHIRIKVNDN-----------------PGNKIGIFFDMVSDKIESV
..| |.|.|.... | . .                             . ...... ...| |.                 |. ..  .|... | || |
rmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev

RR------VGGKVLVHCIAGVSRSASLVIAYLMKYQR--------LNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
|.       ||.||||| |||.|......||||..|.        ..|..| ||....|| . .| .... |......|.
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell

0037934 (Phosphotyrosine protein) phosphatases II 20-158 4.4e-24 80.8 In-house 40-242 (243) alignment
Range on Protein: 20-158
Range on HMM: 40-242/243.0
ARITEWLFLSSC--------QVARDEKLLLEKGITLVINATIEA---------------------------------------------PEQDYKKVKHI
 ..|. |.....         .| . ..| | ||| ... | .                                              ... .  ... 
iyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyh

RIKVND----NPGNKIGIFFDMVSDKIES-----VRRVGGKVLVHCIAGVSRSASLVIAYLMKYQ-RLNLRDAHKLVQDKRPL-IRPNTGFWKELIDYEK
.. . |    .  . .  |.|.| . ||.     ..  ||.||||| |||.|.. |..||||... ...| .| ||....||  . .. .... |.....
ylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeall

KLF
.|.
ell

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 23-157 5.7e-24 78.2 In-house 7-152 (154) alignment
Range on Protein: 23-157
Range on HMM: 7-152/154.0
TEWLFLSSCQVARDEKLLLEKGITLVINATIEAPEQDYKK---------VKHIRIKVNDNPGNKI----GIFFDMVSDKIESVRRvgGKVLVHCIAGVSR
.  |..|| . | .  .| .| |. ..|  |  ..   ..         ........ |..  .|       |... |.| .|..  .|||||. .||||
aiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggven..nkvlvhsdkGvsr

SASLVIAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
||.|.|.|||. ....|  | .|..| |. |.||.|| | |  .||.|
saallisylmdklkislslalellkdsryiikPnqGflkqleifekel

0040438 (Phosphotyrosine protein) phosphatases II 39-161 6e-23 77.0 In-house 105-279 (317) alignment
Range on Protein: 39-161
Range on HMM: 105-279/317.0
LLLEKGITLVINATIEAPEQ---------------------------DYKKVKHIRIKVNDN----------------PGNKIGIFFDMVSDKIESVRRV
.. | |.|.... | . . .                            .. ... ...| |.                |  ..   .| . | .| ||..
mvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrea

----GGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGKN
    ||.||||| |||.|......||||     |...... .| | .. .|| . .. .... |.|.. ... ..
ledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk

0042113 (Phosphotyrosine protein) phosphatases II 20-158 2.1e-22 75.2 In-house 48-243 (245) alignment
Range on Protein: 20-158
Range on HMM: 48-243/245.0
ARITEWLFLSSCQVARDEK----LLLEKGITLVINATIEAPE-------------------------------------------QDYKKVKHIRIKVN-
 |||. ......  . . .    .| | ||| ... | | .                                            .|... ..|..    
yritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylp

--DNPGNKIGIFFDMVSDKIESVRR--VGGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLF
  |..   .   .. . . ......   .|.||||| |||.|.. ...||||     |.....| .| | ....|| .... .... |......|.
wpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 27-157 2.1e-21 69.5 In-house 7-141 (145) alignment
Range on Protein: 27-157
Range on HMM: 7-141/145.0
FLSSCQVARDEKLLLEKGITLVINAT----IEAPEQDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQ
.  |   |.|  .| | ||. ..| .    . . |   .... . |  .|     .   || |.| |.  .  |  |.|||.|||||| .. .|.|||| 
yvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkyc

RLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
 . | .| . |. .| |  ||  | |.|.. ||.|
nmtlseaarqvrsnrllaypnvtflknllnlekql

0038934 (Phosphotyrosine protein) phosphatases II 41-157 3.7e-21 71.1 In-house 53-176 (194) alignment
Range on Protein: 41-157
Range on HMM: 53-176/194.0
LEKGITLVINATIEAPEQDYKKVKHIRIKVNDNPG---------NKIGIFFDMVSDKIEsvRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHK
| ....|||. | . .  |.....   |.. . |          . .  |.|.| ....  .  ||.|.||| ||..|.. ||.|||..........| .
lnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefln..edpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAia

LVQDKRPLIRPNTGFWKELIDYEKKL
|...||| . || .....|  . | |
lfrekRpgaipnqdyleallkrykel

0036941 (Phosphotyrosine protein) phosphatases II 22-169 9.1e-21 69.8 In-house 22-288 (297) alignment
Range on Protein: 22-169
Range on HMM: 22-288/297.0
ITEWLFLSSCQVARDEK----------------------------------------------------------LLLEKGITLVINATIEAPE------
....|.| |. ||. ..                                                          ...| ..| ... | . .       
llpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekca

-------QDYKKVKHIRI--------------------K--------------VNDNPGNKIGIFFDMVSDKIESVRR------VGGKVLVHCIAGVSRS
       ...........                    .              . . | ...   .. . | || ||.       ||.||||| |||.||
qywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRs

ASLVIAYLM--------KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGKNSVQMVDTK
.....|.||        |...... .| | . ..|| . .. .... |.... .|. |. . . . |
gtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk

subfamily_STYXL1_pd Subfamily STYXL1 24-160 1.7e-20 66.8 In-house 17-156 (157) alignment
Range on Protein: 24-160
Range on HMM: 17-156/157.0
EWLFLSSCQVARDEKLLLEKGITLVINATIEAPE---QDYKKVKHIRIKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMK
. |.|   . | ....  .  .  ..| . .| .    . . .| ..|.|.|..  ..  ... . . ||. .. |  |||    |.||||...||||| 
gklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmy

YQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGK
.....|..|.| ... .. ..|| .| . | ..||.|.|.
skkitlkkaykylkkCkenvkPnrafveqlseWekqllge

0039614 (Phosphotyrosine protein) phosphatases II 39-160 6.7e-20 67.2 In-house 120-291 (297) alignment
Range on Protein: 39-160
Range on HMM: 120-291/297.0
LLLEKGITLVINATIEAPEQ---------------------------DYKKVKHIRIK---------------VNDNPGNKIGIFFDMVSDKIESVRR--
.. | |.| ... | . . .                           |. .| .....                 |.    .   .. . ........  
mvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael

-VGGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKLFGK
  ||.||||| |||.|......||||     |...... .| | .. .|| .... .... |.|....|. .
pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr

0051429 (Phosphotyrosine protein) phosphatases II 26-158 7.4e-19 63.9 In-house 24-225 (272) alignment
Range on Protein: 26-158
Range on HMM: 24-225/272.0
LFLSSCQ---VARDEKLLLEKGITLVINATIEAPEQDYK------KVKHIRIKVNDNPGNKIGIFF----------------------------------
|..|..     |.| . | | ||. ... . |   . .|       ...... ..|.    | ...                                  
lyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevm

--------------DMVSDKIESVRRvGGKVLVHCIAGVSRSASLVIAYLMKyQRLN--------------LRDAHKLVQDKRPLIRPNTGFWKELIDYE
              . . . .| ... ||.||||| ||..|.. .| ..|.  ....              |..| . ....|| .... .... | ...
hlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeal

KKLF
..|.
lell

0043336 (Phosphotyrosine protein) phosphatases II 40-156 8.3e-19 63.5 In-house 108-275 (278) alignment
Range on Protein: 40-156
Range on HMM: 108-275/278.0
LLEKGITLVINAT-----------------------------------------------IEAPEQDYKKVKHIRIKVNDNPGnKIGIFFDMVSDKIESV
. | |.| ... |                                                . ...    . .. .  .. |   . ...|.. . .| .
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpe.slsllldflkavreal

RRVGGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKK
.  .|.||||| |||.|.. ....||.     |.....| .| | .. .|| . ..  ... |..... 
edsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle

subfamily_MSG5_pd Subfamily MSG5 46-157 3.2e-18 59.4 In-house 49-160 (165) alignment
Range on Protein: 46-157
Range on HMM: 49-160/165.0
TLVINATIEAPEQDYK--KVKHIRIKVndNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPLIRPN
 |||| . |... ...   ||.  |.   .   ||   .  ..  | . .  . |.||||  |.||||||..||.|||  | ||||..... .   | |.
dlvinvakeindlellvpavkyyhiew..ehdskivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddisps

TGFWKELIDYEKKL
 |.  .|...|  |
iglifqlmeweval

subfamily_PTPMT1_pd Subfamily PTPMT1 63-157 3e-17 57.6 In-house 74-168 (171) alignment
Range on Protein: 63-157
Range on HMM: 74-168/171.0
VKHIRIKVNDNP-GNKIGIFFDMVsDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDYEKKL
|....... |     ..   .. | . ||.|.  | .| ||| || .|||.||..|||| ..|.. .|.| ...||. || ..  || |  ||.||
veqlqlatvDfteapdleklekgv.efiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekl

0047943 (Phosphotyrosine protein) phosphatases II 74-150 9e-14 47.0 In-house 177-264 (273) alignment
Range on Protein: 74-150
Range on HMM: 177-264/273.0
PGNKIGIFFDMVSDKIESVRR------VGGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPNTGFWKEL
| ...   .... . || ||.       .|.|.||| |||.|........|.     |...... .| ||....|| . ..  ... |
pdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl

0051299 (Phosphotyrosine protein) phosphatases II 61-143 2.4e-13 45.7 In-house 182-271 (288) alignment
Range on Protein: 61-143
Range on HMM: 182-271/288.0
KKVKHIRIK--VNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRPN
..|.|.  .   ...  . .  ..|.. . ... .  || |.||| |||.|.. .....|.     | ..... .| | .  .|| . ..
rtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqt

0046845 (Phosphotyrosine protein) phosphatases II 78-140 2.5e-12 42.2 In-house 184-256 (284) alignment
Range on Protein: 78-140
Range on HMM: 184-256/284.0
IGIFFDMVSDKIESVR--RVGGKVLVHCIAGVSRSASLVIAYLMKYQ--------RLNLRDAHKLVQDKRPLI
. ...... .  |. .    ||...||| |||.|.. .....|...|        .... .| | . ..||  
pedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgm

0050432 (Phosphotyrosine protein) phosphatases II 82-142 6.1e-12 40.9 In-house 216-283 (308) alignment
Range on Protein: 82-142
Range on HMM: 216-283/308.0
FDMVSDKIESVRRV--GGKVLVHCIAGVSRSASLVIAYLM-----KYQRLNLRDAHKLVQDKRPLIRP
.... | .| ||..  ||...||| |||.|.. .....|.     | ..... .| | .  .||   .
peilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvq

0048567 (Phosphotyrosine protein) phosphatases II 80-153 1.4e-10 35.7 In-house 58-134 (157) alignment
Range on Protein: 80-153
Range on HMM: 58-134/157.0
IFFDMVSDKIESVRRVGGKVLVHCIAGV---SRSASLVIAYLMKYQRLNLRDAHKLVQDKRPLIRPNTGFWKELIDY
 |. .. .......  |... ||| ||    .|.| |. .||....... ..| ....  || . |    .  | .|
rFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllsly

subfamily_PTPDC1_pd Subfamily PTPDC1 63-139 1.7e-08 29.1 In-house 83-157 (182) alignment
Range on Protein: 63-139
Range on HMM: 83-157/182.0
VKHIRIKVNDNPGNKIGIFFDMVsdKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPL
. .  .  .|   . .   .|.|  |. .     ||| ||| ||  |   |. .||.  .||.  .| |||..||| 
iyvynfgwkDygvasleriLdiv..kvvafalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpk

PTPc_DSPc_SM00012 70-122 4.8e-08 28.5 In-house 15-65 (105) alignment
Range on Protein: 70-122
Range on HMM: 15-65/105.0
VNDNPgNKIGIFFDMVSDKIESVRRvGGKVLVHCIAGVSRSASLVIAYLMKYQ
| ... ..|  ... | .. .   . .. |.||| |||.|.. .| ....  |
vPees.dsilellravkknknkses.skpvvVhCsaGvgRtgtfvaldillqq

subfamily_RNGTT_pd Subfamily RNGTT 54-151 9.4e-08 25.9 In-house 64-168 (189) alignment
Range on Protein: 54-151
Range on HMM: 64-168/189.0
EAP-----EQDYKKVKHIRIKVN---DNPG-NKIGIFFDMVSDKIEsvRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPLIRPNT
. .     | . ...|.......   . |  ...  |  .|.. ..  ..    . |||  |  |.  |...||.. .  ....| .| .  ||    . 
tsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk..knpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiyke

GFWKELI
 . |||.
dylkell

subfamily_DSP23_pd Subfamily DSP23 36-138 1.1e-07 26.6 In-house 23-126 (148) alignment
Range on Protein: 36-138
Range on HMM: 23-126/148.0
DEKLLLEKGITLVINATIEAPE--QDYKKVKHIRIKVNDNPGN---KIGIFFDMVsdkiESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAH
. . ||..|.  ..  | |..   .   ..   |....|       ..  |  .|    |     .  | |||. |  |. ...  ||.| ..|   .| 
qyrylldlgvrylvslteegrphveatpnltlvrlriddyhppaleqvvefvrvv....eeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeai

KLVQDKRP
  |. .||
aevrrlrp

subfamily_Laforin_pd Subfamily Laforin 95-140 2.2e-07 23.9 In-house 109-154 (183) alignment
Range on Protein: 95-140
Range on HMM: 109-154/183.0
VGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKRPLI
 | .| ||| ||| ||...|  .|.     .|.     .  ||| .
kghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv

subfamily_CDC14_pd Subfamily CDC14 89-131 6.2e-07 23.6 In-house 256-298 (328) alignment
Range on Protein: 89-131
Range on HMM: 256-298/328.0
IESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHK
.| . .. |.. ||| ||. |  .|. .||||  |..  .|  
leiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaia

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 51-125 3.6e-06 20.9 In-house 176-248 (305) alignment
Range on Protein: 51-125
Range on HMM: 176-248/305.0
ATIEAPEQDYKKVKHIriKVNDNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLN
 .|| | .. .||.|   . .| |   .      . . .|  |   | . ||| ||. |. |.|.   .  | |.
lviegpgekarkvthy..hwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqlla

subfamily_DSP11_pd Subfamily DSP11 59-137 3.7e-06 20.9 In-house 81-157 (178) alignment
Range on Protein: 59-137
Range on HMM: 81-157/178.0
DYKKVKHIRIKVndNPGNKIGIFFDMVSDKIESVRRVGGKVLVHCIAGVSRSASLVIAYLMKYQRLNLRDAHKLVQDKR
 |.|..    .|  .  . .  | ..|.. .|.    .  . |||  || |.  |.  ||.. . .. .|| .  .. |
kylklncpGhev..pkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeear