Gene MTMR1-3 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR1
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP026_AA protein Get Run
NvecP026_AA_0-114 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR1_pd Subfamily MTMR1 1-114 2.7e-54 176.9 In-house 242-358 (389) alignment 
Range on Protein: 1-114
Range on HMM: 242-358/389.0
RFISLFQVLIEKEWISFGHRFRDRLGH---PTCPSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVS
| |. |.|||||||.||||.|..||||   ......|||.||||.|||||...|||.||.|....|. |.||..|..||.||.|. .||... ....|||
RtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvs

LWSHLNAVKDNYTNSIY
|||..|. |...||..|
lwsyvnsskeeftnply
0040695 (Phosphotyrosine protein) phosphatases II 6-114 3.3e-43 141.9 In-house 247-358 (388) alignment 
Range on Protein: 6-114
Range on HMM: 247-358/388.0
FQVLIEKEWISFGHRFRDRLGH---PTCPSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSLWSHL
|||||||||.||||.| |||||    ......||.||.|||||||...|||.||.|. ..|| ||||. | .||.||.|. .||  . . . |.||||.|
FqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyl

NAVKDNYTNSIY
.  |. ..| .|
lsrkseflnplY
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 2-114 3.9e-42 136.8 In-house 253-367 (404) alignment 
Range on Protein: 2-114
Range on HMM: 253-367/404.0
FISLFQVLIEKEWISFGHRFRDRLGH--PTCPSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSLW
 |. |.|||||||.|||| | .| |.   .  ..||||||||.|||.|. ||||. |.| ...|.|. |...|  ||.|||.. .||... ..  |||||
tiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslW

SHLNAVKDNYTNSIY
. |.| |..| |..|
alleankseylnply
subfamily_MTMR3_pd Subfamily MTMR3 2-114 1.6e-41 135.5 In-house 300-415 (442) alignment 
Range on Protein: 2-114
Range on HMM: 300-415/442.0
FISLFQVLIEKEWISFGHRFRDRLGHPTC---PSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSL
 .  |.||.|.||..|||.| || ||        .|.|.|||.||.| |...|||..|.|.  .|.||. |  |. || || |. .||..  ....|.|.
tleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvkertlsv

WSHLNAVKDNYTNSIY
|| |.| ...|.| .|
Wsllrakekeyrnlly
subfamily_MTMR6_pd Subfamily MTMR6 1-114 3.9e-41 133.6 In-house 253-367 (397) alignment 
Range on Protein: 1-114
Range on HMM: 253-367/397.0
RFISLFQVLIEKEWISFGHRFRDRLGHPTC-PSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSLW
| |  |.|||||||.||||.| .| |.    . . ||||.|||.||||. .||| ||.|  ..||.| ||| |  ||.|| |. ..|... ... | |||
rtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslw

SHLNAVKDNYTNSIY
..| . ||.|.| .|
ayllerkddylnply
Myotub-related Myotubularin-like phosphatase domain 3-87 4.1e-36 117.5 Pfam-A 263-351 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 3-87 4.1e-36 117.5 In-house 263-351 (353) alignment
subfamily_MTMR9_pd Subfamily MTMR9 1-114 3.4e-31 100.7 In-house 247-366 (393) alignment 
Range on Protein: 1-114
Range on HMM: 247-366/393.0
RFISLFQVLIEKEWISFGHRFRDRLGHPTCPS----QRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTV
| .  |. |||.|||  || |  |  . .  .    ...|.|| |||||.|. .||| .| | ...|  |  |  |  ||.||..| .||... ... ||
RtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktv

SLWSHLNA--VKDNYTNSIY
||||..|.  . ....| .|
slwsyvnrpeklkqflnply
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 1-112 7.8e-31 99.2 In-house 263-375 (405) alignment 
Range on Protein: 1-112
Range on HMM: 263-375/405.0
RFISLFQVLIEKEWISFGHRFRDRLGH-PTCPSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSLW
| |  |||||||||.||||.|  |||| |    .||||| |||||..|. .|||  |.|| . || ..| . |  .| || |  ..| .  .   |.|.|
rtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiw

SHLNAVKDNYTNS
| .|   ... | 
sevnlnvnkflnp
subfamily_MTMR10_pd Subfamily MTMR10 6-98 1.3e-30 98.5 In-house 221-314 (380) alignment 
Range on Protein: 6-98
Range on HMM: 221-314/380.0
FQVLIEKEWISFGHRFRDRLGHPTCPSQ-RSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSL
|| ||.|||.. || | ||||| .  .. .||.|| |||||.| ..||||.|.||  .|..| |...|  |..|| |. ..|  |   .. . .
fqsliqkewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvsssplli
subfamily_MTMR5_pd Subfamily MTMR5 3-91 2.1e-29 94.7 In-house 329-419 (483) alignment 
Range on Protein: 3-91
Range on HMM: 329-419/483.0
ISLFQVLIEKEWISFGHRFRDRLGH-PTCPS-QRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFI
.  |.||.||||..||||| .|  . ... |   .|.||||||||.||..||| || |   ||  || |  |. |  ||..  .|| .. .
leGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgl
subfamily_pats1_pd Subfamily pats1 35-114 1.3e-23 75.3 In-house 553-632 (691) alignment 
Range on Protein: 35-114
Range on HMM: 553-632/691.0
SPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSLWSHLNAVKDNYTNSIY
||||.|||| |||..|.||  |.|   .|| | ... |  ||||||.. ...    . . . |.||  |  | ...| .|
sPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinlly