Gene MTMR6 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR6
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP031_AA protein Get Run
NvecP031_AA_126-509 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR6_pd Subfamily MTMR6 110-507 2.8e-220 723.5 In-house 1-397 (397) alignment 
Range on Protein: 110-507
Range on HMM: 1-397/397.0
LYAFSYSPQTEKLTQSAGWALFDIKSDYTRMGVPSDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQP
||||||.|...| ....||.|.|.|..|||||||.. ||.|.||||||||||||. ||||||||||||||||.|||.|||||||..||...||.||||||
lyafsykpkkdkeekvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqp

LGGFKGRCPEDEQMIQALLNSNPNSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVGESPKTPAgAFYSGLEAS
|.||. || |||....|. ..||||...|.|||||.||||||.|||||||.||.|.|.||||||||||||||.|| |.||||... |. . .|.||||.|
lsgfsarcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvs.eflsgless

NWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQKEFSPVFLQFLESIW
.||||||..||.|.|||||||.|.||||||||||||||||.|||||..||||||||.||.||||||||||||||..|||||..|.||.||.|.||||..|
gwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvw

QLLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLYREVTQDDALWPDTSPQAIRFWRAMYNRYDN
|||.||| .|.|||||||.|||||||||||||||||.|.|||| | .||.|||.|.... .||.||||.. |....|.|||.|.|...|||.|||.|.
qlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwralynrfdk
0040695 (Phosphotyrosine protein) phosphatases II 126-507 3.3e-148 487.3 In-house 6-387 (388) alignment 
Range on Protein: 126-507
Range on HMM: 6-387/388.0
AGWALFDIKSDYTRMGVPSDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPLGGFK-GRCPEDEQMI
 || |.||. ...|.|.. |||  . .|..||||..|| .|.||||...|.|. ..||||.||.||||..|. ..|...|.||||.|.  .|. |||...
egwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledekll

QALLNSNPNSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVgeSPKTPAGAFYSGLEASNWLKHIKNILDTSVF
.|.|...||.....|||.||.||||||||.|.|.|.||.| |....|..|.||||.|.||.|.|...   .  .   ..| || |.||..||.||...|.
eailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldac..lnvpdslnllslleesgwldliklilelavl

IAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQS--DQKEFSPVFLQFLESIWQLLQQFPFSFQFN
|.| .  .. |||||||||||||.| .||| ..|||||||. ||||||||||||||||| ||.|.| |  |.||||||||.||. .||||.|||..|.||
ivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFn

ERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLYREVTQDdALWPDTSPQAIRFWRAMYNRYDN
||.||.|.||.|||.|||||.|..|||..|....||.||| |.... |.. ||||   . .  |.| .|.. ...|  .|.|...
erlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpssle.vllpslsvldlllWleyylrwlp
subfamily_MTMR1_pd Subfamily MTMR1 125-507 4.3e-148 485.7 In-house 4-388 (389) alignment 
Range on Protein: 125-507
Range on HMM: 4-388/389.0
SAGWALFDIKSDYTRMGVPSD-LWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPLGGFKG-RCPEDEQ
. ||...| .... |.|.... || .|.|||.||||||||..|.|||... |.| ....|||.|||||||...|..||.. |.|||| | .| |..|||.
edGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedek

MIQALLNSNPNSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVgeSPKTPAGAFYSGLEASNWLKHIKNILDTS
..||.|..| .|. ..|.| |.. || ||.| |||||||..|.|... |. |.||||.|.|| |. |.|   |..    ..| ||...||.||| ||...
ylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelv..lpnvddkkwlsalestkWlehiklilaga

VFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGL--LQSDQKEFSPVFLQFLESIWQLLQQFPFSFQ
| |...| .||.|||||||||||||||  ||| ..||.|||||.||.||||||||||||||..| |    .| ..| |||||||....||| .|||. |.
vkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFe

FNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLYREVTQDDALWPDTSPQAIRFWRAMYNRYDN
|||.||.|| ||.||| ||||| |..|||..  . ..| ||| |. .. ... ||||.| .....| | .| . .. |.  | |.. 
fneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyylrwnp
Myotub-related Myotubularin-like phosphatase domain 109-451 2.2e-143 470.3 Pfam-A 1-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 109-451 2.2e-143 470.3 In-house 1-352 (353) alignment
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 111-506 5.8e-139 455.7 In-house 1-403 (404) alignment 
Range on Protein: 111-506
Range on HMM: 1-403/404.0
YAFSYSPQTEKLTqsAGWALFDIKSDYTRMGVPSD-LWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQP
.|||||..  .|.   || ..| ...|.|.|..|.  |  ...|.|||||.|||..| ||.| . | |. .. |||.||.||||. |.|... . |.|||
fafsysekksvle..dgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqp

L-GGFKGRCPEDEQMIQALLNSNPNSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVgESPKTPAGAFYSGLEA
| |  | |. |||..|...  ...... .||.|.||..|| ||.| |.|||. . |||.. .| .||||| .|.|| |. ..| .| ..    ..| || 
lvGltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkav.nsiiekeknwlseles

SNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGL-LQSDQKEFSPVFLQFLES
|.|| |||..| .|  |.. .  || |||||||||||||.| .||. ..||||||||.||.||||||||||||||..|.|   . ...|.||.||||.. 
srWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidc

IWQLLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLY--REVTQDDALWPDT-----SPQAIRFWRA
..||..||| ||.|||.||... |..|||.||||| ...||| .  |.| | ||| .. .| |.| ||||  ..  | ..   ..     ... |..|. 
vyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWse

MYNRYD
.| |. 
yylrwr
subfamily_MTMR9_pd Subfamily MTMR9 113-505 4e-110 360.6 In-house 2-392 (393) alignment 
Range on Protein: 113-505
Range on HMM: 2-392/393.0
FSYSPQTEKLtqSAGWALFDIKSDYTRMGVPSDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPLGG
| | . ...|    |.  || . ..... ..|| |  .. ||....| .||. . |||. . | |. |..||. ||.||||..|| |.|.. |.|||| |
ffyrsvatil..edgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcg

FKG-RCPEDEQMIQALLNSNpnsKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVGEsPKTPAGAFYSGLEASNW
 .| || |||..... |...   |  .|||||    | ..|. | | | |. | ..| .   .|..... .|| |.||.. .  .. .. |.| ||.|.|
ssgkrckedekllnlvlkkl...kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsd.aglstdkflsrleksgw

LKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQ---KEFSPVFLQFLESI
|......|.... .|...  |.|.|.|| ..| | | |  ||| .||||..||..||. |||.||.  || |. |.  .   .   |. .|||| ||...
lsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcv

WQLLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMW--QNISDYANPLYREvtQDDALWPDTSPQAIRFWRAMYNRY
.|.|.||| || |||..| .|. | ||.||||||.....||..|.| |.| ||| |.   .......|||| .  ... .||   ||....|. .| |.
yqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea..naeviwpsvapqslelWselylrw
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 125-505 2.2e-104 341.5 In-house 13-404 (405) alignment 
Range on Protein: 125-505
Range on HMM: 13-404/405.0
SAGWALFDIKSDYTRMGVPSD-------LWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPLGGF-KGR
  || ... | .| |. .  |        |  |..||.|..| .|.  | | . |.   |     |||.||.| ||.   |..|.. |||||| |  . |
idgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierar

CPEDEQMIQALLNSNPnSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVGESPKT------PAGAFYSGLEASN
|||||    .|  | | || .|..|.||.|||.|| | | |.|    | |.|. |. | ||||.|.|| |.   .  | .           |.  .| . 
cpedelycsslalsap.sktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetg

WLKHIKNILDTSVFIAKAVaMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQKEFSPVFLQFLESIWQ
|. ||| ||... | |. . .   |.||||||||||| |  ||. |.||||||||.|||||||||||||||||. | | |  ...| ||.| |||.  .|
wishiksileaatfsaeli.lkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfq

LLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLYREvTQDDALWPDTSPQAIRFWRAMYNRY
||.|||. |.|   .|| . | ..||..|||| ||.|.| .  .  .| |.|  .  |.  . || |    . ... |    ... .|.| | |.
llsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynp.qdiqsikpklysrclelwkacymrv
subfamily_MTMR3_pd Subfamily MTMR3 233-503 9.8e-96 314.2 In-house 171-440 (442) alignment 
Range on Protein: 233-503
Range on HMM: 171-440/442.0
NSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVGESPKTPagAFYSGLEASNWLKHIKNILDTSVFIAKAVAME
..| . ||| |    |.|||| | |.| |..|.|.. .|.|. ||| .|.|. .. ... .||...   ..| ||. .||... ..| ..| ...||  |
ekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslrallsqspdes..nwlsalektkWlqnlsvllkaavkvveavdke

KASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQ--SDQKEFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLH
. .||||||||||||.|  .|| ..|||||||..||.||.|.|||.|||||.||||  .   |..| .|||||.|... || .||| ||.||| ||. | 
grpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklv

DHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLYREVtQDDALWPDTSPQAIRFWRAMYN
 | ||| |||||.|..|||..  . .|| |.| .. ..  .| | ||.|  ..  |.| .| .....|...| 
qhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykek.teavllpavsvrelklwsevyl
subfamily_MTMR5_pd Subfamily MTMR5 239-465 1.9e-62 203.6 In-house 201-440 (483) alignment 
Range on Protein: 239-465
Range on HMM: 201-440/483.0
IVDTRPRLNALANRAAGKGYESeDFYENVKFQFVGIENIHVMRQSLFKMLEVVGESPK---TPAGAFYSGLEASNWLKHIKNILDTSVFIAKAVAMEKAS
    . .| .| ...  |...| ... .. |  | . .|  ...|. |.| .   | .   .   .|.. .|.|.||. |...|. |. ... . ....|
lrarkaaLYvlgeksqlknvks.evdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgss

VLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQK-EFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVY
|||   |||| |||  ||| ..|||||||..||.||.|||||.|||.||.|. . .| |.  |.|||||||. ..|. .||| .| ||. .| .|  |  
vlvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsv

SCQFGTFLGNCQKERRDLGL------PKR----TYSLWGYM
|..| ||| ....|| . ||      .||    . |.| |.
snrfrtfllDseyerlesgllyeekaekrakkagksvwdyi
subfamily_MTMR10_pd Subfamily MTMR10 301-452 7.1e-50 161.8 In-house 154-305 (380) alignment 
Range on Protein: 301-452
Range on HMM: 154-305/380.0
AFYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQKEFSPV
 ..| || ..||. .. .| |.. ..|.|. .| ||..  |.| |     .|||...|||.|||| ||| ||.||| . ||.|.||.| .....|. |||
kwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespv

FLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDL
|| ||.  .|||.|||..|.|.|.||..|.|...|. |.||| |....|   
fllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlka
subfamily_pats1_pd Subfamily pats1 395-480 4.6e-27 86.7 In-house 550-635 (691) alignment 
Range on Protein: 395-480
Range on HMM: 550-635/691.0
KEFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQNISDYANPLYREV
. |||.|.|||. .||| ..||| |.||| .||.| ....| .||.|| .  |.. .  . ||. |.| .. || | . | ||.. 
rsfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhs
subfamily_MTMR3_pd Subfamily MTMR3 121-230 5.5e-24 77.7 In-house 17-128 (442) alignment 
Range on Protein: 121-230
Range on HMM: 17-128/442.0
KLTQSAGWALFDIKSDYTRMGV-PSDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPLGGFKG-RCP
 |...|  |  ..|....|.|   .. |  ...|.|..|| .||. | |||| | . |  ...||| .|||.. . ||...|.. |||||  |. | |. 
fllraasvaeeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrna

EDEQMIQALLNS
|||....|. ..
edekllkaiaka
subfamily_pats1_pd Subfamily pats1 273-389 1.2e-21 68.8 In-house 342-459 (691) alignment 
Range on Protein: 273-389
Range on HMM: 342-459/691.0
GIENIHVMRQSLFKMLEVVGeSPKTPAGAfYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQT---CSLASIILDPYYRTIHGFQ
 .   . ...  |..|. .  |   .  . .. .| | |.  .| .|...| ... .   .. .|   .|. . . .     ||| ...||.|||. ||.
slPtrekveerffdllqsil.sldgsdde.wkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrtldGfk

VLIEKEWLSFGHKFTDRCGL
|||||||||.|. |....  
vliekewlsyGfPfskinyh
FYVE FYVE zinc finger 613-677 1.2e-14 44.0 Pfam-A 2-68 (69) alignment 
Range on Protein: 613-677
Range on HMM: 2-68/69.0
KWKSVRDVSQCSTCSLPIAFLSRKYHCWNCGEVFCRRCIERQCSLP--AHYSENTVPVCKQCYKRIQ
||.. .....|. |. .  ...|. || .||.|.|..|.. ... .   . .|. | |||.|.....
kwvddaeakkCeiCakkFsltrrrhhCrlCGkvvCskCsskrvekleeesaeekevrvCkeCleels
PTPc_DSPc_SM00012 308-432 2.2e-11 39.2 In-house 38-103 (105) alignment 
Range on Protein: 308-432
Range on HMM: 38-103/105.0
AsnwlkhiknildtsvfiakavameKASVLVHCSDGWDRTAQTCSLASIILDPYYRTihgfqvliekewlsfghkftdrcgllqsdqkefspVFLQFLES
                         ...|.||||.|..||.. . |. .. . ...|                                    ...... 
s........................skpvvVhCsaGvgRtgtfvaldillqqleket...................................kevdifqi

IWQLLQQFPFSFQFNERFLLTLHDH
...| .| | ..|..| .|  .. .
vkelrkqRpgmvqteeqylflyral
subfamily_MTMR5_pd Subfamily MTMR5 135-209 1.3e-10 32.7 In-house 12-93 (483) alignment 
Range on Protein: 135-209
Range on HMM: 12-93/483.0
SDYTRMGVP-------SDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQP
 ||.|.|.        .. .  .. ||.|..|..||... ||..   . .   ..   ..||||  . |. ..| . | ...
qdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
subfamily_pats1_pd Subfamily pats1 128-210 9.7e-09 26.1 In-house 6-90 (691) alignment 
Range on Protein: 128-210
Range on HMM: 6-90/691.0
WALFDIKSDYTRMGVPSDL-WTATQ-LNKdyELCDTYPNILYVPKSATKEVLVGSSRFRSRgRLPVLSFYHKSTQAA---VCRCSQPL
.  . .  .. |...  |. |  .. |..  .|.. ||.   |||. . |.|| . | ||  ..||||. ... ...   .|   ||.
fdiyslliegqrlkldldkdwrvveflsr..dlseiyPkrilvPklvsdellvsyvrkrss.kiPvlswsnqnnksslfricvynqpf
subfamily_MTMR14_pd Subfamily MTMR14 326-388 8.5e-07 20.1 In-house 260-329 (357) alignment 
Range on Protein: 326-388
Range on HMM: 260-329/357.0
AKAVAMEK-ASVLVHCSDGWDRTAQTCSLASIILD--P-YYRTIHGFQVL---IEKEWLSFGHKFTDRCG
 | |  .. . .||||  |||||    ||  . |      .....  ..|   .  .|. |||...||  
lkyvkededsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrlk
0045098 (Phosphotyrosine protein) phosphatases II 305-358 1.5e-06 23.3 In-house 172-231 (278) alignment 
Range on Protein: 305-358
Range on HMM: 172-231/278.0
GLEASNWLKHIKNILDTSVFIAKAVAM------EKASVLVHCSDGWDRTAQTCSLASIIL
    . .|.... |..   ..|. . .      ..  |||||| |..||.  . .  .. 
lpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmle
subfamily_MTMR10_pd Subfamily MTMR10 138-249 7.7e-06 16.9 In-house 17-126 (380) alignment 
Range on Protein: 138-249
Range on HMM: 17-126/380.0
TRMGVPSDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVcRCSQPLGGFKGRCPEDEQMIQALLNSNPNSkFI
..  . || . ... |.  . . |.|. ..||.| ... .   ||    .| |.... | ...|.. |.|.     .    . |.| . . ...|.   .
kekktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaall.rlsalqeaesadkekeekmlelvrkchpan.dv

YIVDTRPRLNAL
 .||.  .|. .
klvdlsdelpsi
0049772 (Phosphotyrosine protein) phosphatases II 311-349 9.5e-06 21.0 In-house 198-228 (314) alignment 
Range on Protein: 311-349
Range on HMM: 198-228/314.0
WlkhiknILDTSVFIAKAvaMEKASVLVHCSDGWDRTAQ
.      ...   || .|   ..  |||||..|..||. 
d......fdeflefieea..dkggpvlvHCkaGkgRtgt