Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 3-241 | 1.8e-175 | 575.5 | In-house | 1-239 (239) | alignment | ||
Range on Protein: 3-241
Range on HMM: 1-239/239.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||...|..|||||||||||||||||||||||||||||||||||
eaakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
|||||||||||||||||||||||||||||||||||||||
akkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 4-242 | 2.4e-175 | 575.1 | In-house | 1-239 (239) | alignment | ||
Range on Protein: 4-242
Range on HMM: 1-239/239.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||...|..||||||||||||||||||||||||||||||||||||
aakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds
TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
tskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
KKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
|||||||||||||||||||||||||||||||||||||||
kkqktvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 2-242 | 5.8e-116 | 383.4 | In-house | 40-280 (564) | alignment | ||
Range on Protein: 2-242
Range on HMM: 40-280/564.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
|||.| .||||||||||| ||||||||.|. .|. |||||||.. |. ..|||||||| . |||||.|... ..||||| | | .|.|||.|||
weaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWP
DS-TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAML
.. | .| .| ||| ..| .|||.|||| ... . | | | |.||| |||.|||..||..| |.||... . |.| |.|.||||||||||.|.||||||
ekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividaml
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
...|..|||||..||||.|..|..|||| |||.||| |.|||
erikeektvDiyqyvkalrkqRnamVqteeQYiFiheailea
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 10-241 | 8.3e-102 | 334.4 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 10-241
Range on HMM: 3-237/237.0
NKAKNRYANIVTYDHSRVVLEKLSNDphSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS--TSKY
||.||||.|||.||||||||. .. ||||||.||...||.|| |||.|| . |||.|.|||. ||||||||||| ..|||.|||.. . |
nkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
CNLRVTLRKTEVFADYIIRTFVMSQVG-QTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDS--LPGARPWVIHCSAGVGRTGAFLVIDAMLRQAK
| |.|.| | |.|| .|....|. . . | |...||.||.|||.||||...|.| .|..| . | .. . ||.||||||||||| ||||||||||||
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
KQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
..| |||.|||..| ||||...|| .|||||| ..||
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 4-242 | 1.6e-99 | 327.2 | In-house | 3-241 (250) | alignment | ||
Range on Protein: 4-242
Range on HMM: 3-241/250.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKkCHQYWP-D
||| || |||||.|...|.||||||| . | .|||||||.| ||.. ||.||||| . |||||...| .||||| | | .|. .||||| .
vakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve
STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLP-GARPWVIHCSAGVGRTGAFLVIDAMLR
. || ...|.| ..|.||||..|....|. ...|| | |.||.||||||||..|||||.|..|. . |..| ...|||||||.|||..|||.|
kaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavle
QAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
..||.|.||.|...|..|.||||.|.. |||||.. ..|.|
rlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 2-242 | 2e-98 | 324.3 | In-house | 48-289 (298) | alignment | ||
Range on Protein: 2-242
Range on HMM: 48-289/298.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPkAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
.|.|.|. || |||||.|...|.||||||| ..| .|||||||.| |.|.. |.||||. . |||||...| .||||| | | .| |.|.|||
kevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn.afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywP
D-STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD-SLPGARPWVIHCSAGVGRTGAFLVIDAM
| . .| ...|.|...|.|||.|.|.. .|. ...|| | | |||.|||||||..||.||.|.||. . . | .| ...|||||||.|.| .||..
degketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsv
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
| ..||...||.|..||..|..||..||| ||||||. |||||
lervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlea
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 5-242 | 2.1e-92 | 304.6 | In-house | 41-279 (318) | alignment | ||
Range on Protein: 5-242
Range on HMM: 41-279/318.0
AKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST
. . |||||||||||..|||.|| |..|.... ||||||.|. | . |||||.|. . |||||.|. .|||||| . | |.|.|.|||..
slepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyr.rkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskg
S-KYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDS-LPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
| .| .|.|.|... ..||..|.| ... .. |.| | |||.| |||.|||. .. .| | |...| .||.| |.|||||||||| |...|..|..
srsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdiller
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
.|....||.|..|| .|| |. |||| .||.||. ..|||
ikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllea
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 3-241 | 1.3e-86 | 285.3 | In-house | 44-283 (293) | alignment | ||
Range on Protein: 3-241
Range on HMM: 44-283/293.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
.||.. ||.||||| ||..|||||| |..|.....||||||.|...| ||. .||||| . |||||.|... .||||| |.|. |.||..|||.
kaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgyn.sprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPa
S--TSKYCNLRVTLRKTEVFADYIIRTFVMSQvgQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDS--LPGARPWVIHCSAGVGRTGAFLVIDA
. | ...||| ..|. |..||.. ... ..||| | ||||| ||| |||. ....| . |.. . .|| |.||||||||||.|. .|
deepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdr
MLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.|.. ... .|||| | ..||.| ..||| .||.||| .||.
llqaieeedyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 3-241 | 2e-85 | 282.1 | In-house | 61-297 (308) | alignment | ||
Range on Protein: 3-241
Range on HMM: 61-297/308.0
EAAKKRVNKAKNRYANIVTYDHSRVVLeklsnDPHSDYINASYLRDYD-GSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
..|.. || |||| .|. ||||||.| |..|||||||| . |. ..|...||||| . .|||||.|... |||||| |.| ..||.||||
svallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwp
D----STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSlpGARPWVIHCSAGVGRTGAFLVID
. .. .| ...|||...||..||..||. .. .| |.|.|...|.| ||| |||......| . ... | . | |.||||||||||.|...|
lelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfiald
AMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.|.| .|...||.|..|| .|| ||.|||| |||.|.. |.||
llleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralle
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 4-241 | 2.4e-85 | 281.8 | In-house | 43-284 (288) | alignment | ||
Range on Protein: 4-241
Range on HMM: 43-284/288.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPKaYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP-D
||.. |. |||| .|. ||||||.| |.....||||||||.. |. . | .||||| . .|||||.|... ||||||.|.| ..||.|||| .
aallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplg
STSKYCNLRVTLRKTEVFADYIIRTFVMSQV----GQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDA
.. .| ...|||...||..||..||. .. . |. |.|.|...|.| ||| |||......| . |.. | .| | |.||||||||||.|...|
gsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdl
MLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.|.| .|...||....|| .|| ||.|||| |||.|.. |.||
lleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 4-242 | 4.7e-84 | 277.2 | In-house | 42-282 (319) | alignment | ||
Range on Protein: 4-242
Range on HMM: 42-282/319.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
|.| || |||| ||..||..|||| .| . . |||||||.. |. ...||||. . |||||.|.|. ..||||.| | | |...|||.
saskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqer.ekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpee
T-SKYCNLRVTLRKTEVFADYIIRTFVMSQ-VGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDS-LPGARPWVIHCSAGVGRTGAFLVIDAML
. .| .| ||| . | .||||| . . . .. | | | ....| |||..||..||..| | ..| | . ..| |.||||||||||.|.|.||||
nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldaml
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
. |.. ..|.|..|. .| |. |||. ||| ||. |.|||
ervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyeallea
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 3-242 | 9.6e-84 | 275.9 | In-house | 36-276 (314) | alignment | ||
Range on Protein: 3-242
Range on HMM: 36-276/314.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
.|||| |..|||. .|..||.|||.| . .||.||||||... | |.|.|.||| . ||||....|. . ||||| |.| . || .|||.
daakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsyk.rpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe
STSKYCNLRVTLRKTEVFADYIIRTFVMSQ--VGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAML
|..| ...|.| .||. |....|.| ... || | | | |..|. ||| .||..||..|.| |.. | . ..| . |.||||| ||||.|..|| .|
dtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
......||.|| ||..|. .. ||.| |||.||. ..|||
dmieregvvdvfnavktlrsrkvnmveteeqykfiydvilea
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 3-241 | 2.3e-82 | 271.9 | In-house | 21-272 (284) | alignment | ||
Range on Protein: 3-241
Range on HMM: 21-272/284.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSND-PHSDYINASYLRDYD----GSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCH
..|.. |. |||| .|. ||||||.| |..| ..||||||||.. || ..|..||||| . .|||||.|... ||||||.|.| ..||.
svallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekca
QYWP--DSTSKYCNLRVTLRKTEVFADYIIRTFVMSQVG-QTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSL--PGARPWVIHCSAGVGRTGA
|||| ... .| ...|||...||. ||..||. .. .| |.|.|...|.| ||| |||.... .| . |.. . || | |.||||||||||.
qYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGt
FLVIDAMLRQAKKQK---TVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
|...| .|.| .|.. .||....|| .|| ||.|||| |||.|.. |.||
fialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealle
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 5-241 | 2.6e-82 | 271.4 | In-house | 41-281 (305) | alignment | ||
Range on Protein: 5-241
Range on HMM: 41-281/305.0
AKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST
|| .||||||...|...|..|. | . .....||||||||. |... |.||..|| . ||||....|. .|||||.|.|| |.||.||||.|.
gkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrk.kkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesk
SK---YCNLRVTLRKTEVFADYIIRTFVMSQ-VGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGAR-PWVIHCSAGVGRTGAFLVIDAM
.. . .. |.|. .. ..|||.| . .|. .. |.| | ||..| |||.||||.||..| | ....|| . | ..||||||||||.|...| .
tekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdia
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
| ..|| ..||.|...|..|. |. |||| .||||.| |. |
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdalde
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 3-241 | 1.1e-81 | 269.2 | In-house | 51-293 (330) | alignment | ||
Range on Protein: 3-241
Range on HMM: 51-293/330.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
|.|.| || |||. ||. ||.|||.| ... ..|||||||.. | . .||.|| |||||.|. . . ||||| | | ...||.|||||
elaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykek.dkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPd
ST-SKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTE----ERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVID
| |.||......| || .| |.. |.... .| | |.||| ||| ||| . .| | .|. | | | |.||||||||||.|.|.|
eGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivld
AMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
|.| . | .. ||.|. || .| ||.|||| |||.||. ..||
avlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlle
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 3-240 | 1.1e-81 | 269.0 | In-house | 40-276 (288) | alignment | ||
Range on Protein: 3-240
Range on HMM: 40-276/288.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
.|... ||. |||| ||..||. || |.|| . . .|||||||. ... . |.|||||| . .|||....... |||||.|.|| |.||..||||
tagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgek.kkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPd
STS--KYCNLRVTLRKTEVFADYIIRTFVMSqvGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAML
. .| .. |||.... |.. |.. . ...|. . ||....|||.|||. .. .|.|.|.. . . | ..|||||||||| |...||..
adkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdali
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
. ......|... |. .|. |. .||| .||.||. ..|
daveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 2-242 | 1.6e-81 | 269.3 | In-house | 39-286 (563) | alignment | ||
Range on Protein: 2-242
Range on HMM: 39-286/563.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHS-DYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYW
|...|. || |||| |||.||.||| |..|.. .. |||||.|. | ||.||||| . . |||||.|... .|||.| | | ...||..||
aehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyq.kskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYW
PDS-TSKYCNLRVTLRKTEVFADYIIRTFVMSQ----VGQ--TEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAF
| . .| .|.||| ..||.| | .||.|. . .. .|. |.|||.| |||.|||.... || .| . | | |.|||||||||| .
PkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGty
LVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
.|.|..|.| .....|..|. .| || |...||| |||.|.| |.|||
ivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdallea
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 2-241 | 4.9e-80 | 263.8 | In-house | 41-277 (315) | alignment | ||
Range on Protein: 2-241
Range on HMM: 41-277/315.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
. ||| || |||| ||..||.||| | | |||||||.||... |. .. |||.|| .||||....| |||||.|.||.|.|. .|||
ldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGyn.kkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywp
DSTSKYCNLRVTLRKTEVFADYIIRTFvmSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLR
| | .. ||... ||. .| .||. | | . . | |.|.|.| ||| |||.|..... | |.. . . . |.||||||||||.|. .||.|
dkkviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavld
QAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
||. .. .|..|... .|. | .|||. ||| ||. |.||
qaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 4-241 | 5.3e-80 | 264.2 | In-house | 33-275 (297) | alignment | ||
Range on Protein: 4-241
Range on HMM: 33-275/297.0
AAKKRVNKAKNRYANIVTYDHSRVVLeklsNDPHSDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP--
.|.. |. |||| .|. |||.||.| .|..||||||||. | . ....||||| . .|||||.|... |||||| |.| ..||.||||
vallpenleknRykdilpydhtRVkl....ddegsdYinAsyv.dgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywple
-DSTSKYCNLRVTLRKTEV--FADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK--DSLPGARPWVIHCSAGVGRTGAFLVI
... .| ...|||...|| ..||..||. .. .| |.|.|...|.| ||| |||.... .| . ... | . ||. | ..||||||||.|.|...
egesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaa
DAMLRQAK---KQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
| ||.| . |...|||...|| .|| ||..||| |||.|.. |.||
dlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyealle
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 4-241 | 1.6e-79 | 262.8 | In-house | 37-274 (317) | alignment | ||
Range on Protein: 4-241
Range on HMM: 37-274/317.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP-D
|.. .|| |||| .|. ||||||.| |..|..|||||||| | ....||||| .|||||.|... .|||||| | | ..||.|||| .
vaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyv.dgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplg
STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
.| .| ...|||...|. |....||. .. | |.|.|...|.| ||| |||.. . .| . ... . .. | ..||||||||||.|.... ||.|
etltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleq
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.| ..||... || .|| ||..||| |||.|.. |.||
lekeggvdveeavkelreqRpgavqtpeqyrflydalle
|
|||||||||
DSPc_SM00195 | 4-241 | 1.9e-79 | 262.1 | In-house | 20-260 (263) | alignment | |||
Range on Protein: 4-241
Range on HMM: 20-260/263.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYdGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
|.| ||.|||| ||. |||.|| |.| ....||||||.|.. . ..|.|||||| |||||.|.|. .||||| | .|.||..|||..
eaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpee
---TSKYCNLRVTLRKTEVFA-DYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAM
.... ...|.|...| ..|.||. ... |. |.| |.||... |||.|||. .. || | |...|.. | |.||||||||||.|..|| .
sggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
|.. ...|.||||. ||..|. ||.||||.||| ||. |.||
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
PTPc_SM00194 | 4-241 | 1.9e-79 | 262.1 | In-house | 20-260 (263) | alignment | |||
Range on Protein: 4-241
Range on HMM: 20-260/263.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYdGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
|.| ||.|||| ||. |||.|| |.| ....||||||.|.. . ..|.|||||| |||||.|.|. .||||| | .|.||..|||..
eaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpee
---TSKYCNLRVTLRKTEVFA-DYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAM
.... ...|.|...| ..|.||. ... |. |.| |.||... |||.|||. .. || | |...|.. | |.||||||||||.|..|| .
sggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
|.. ...|.||||. ||..|. ||.||||.||| ||. |.||
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 2-241 | 6.3e-79 | 260.4 | In-house | 35-274 (515) | alignment | ||
Range on Protein: 2-241
Range on HMM: 35-274/515.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGsPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
|.. .| |||| ||. || .|| || . ..|||||.||||.. .| |||||.|| ||||...||. |.|.| | || | || .|||
qtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdn.dkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWP
D---STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQteERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDA
| . |. ...| | .| .. |.|.. . . . | | |.||| |||||||. ....| | ... | . | .||||||||||| .. ||
dkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisids
MLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.. .||. ..||.||.|. ||..||..||| ||| ||. ||||
vvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavle
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1-242 | 1e-78 | 259.3 | In-house | 32-275 (281) | alignment | ||
Range on Protein: 1-242
Range on HMM: 32-275/281.0
PSEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGsPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYW
...|.|. |. |||| ||| ||..||.... ... ..|||||... |.| .|.|||||| . .||.|.|... ..|||.| ||. | |||.||
tataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykg.ekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYW
PDST--SKYCNLRVTLRKTEVFADYIIRTFVMsQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGA-RPWVIHCSAGVGRTGAFLVID
|| . || ...|. ..| | || |.| . . ..|.| | | ..| |||.|||. ....|. |....| . . | ||||||||||||... .|
Pddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialD
AMLRQAKKQ-KTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
........ ...|. . |. .|..| |||| || |...|||.|
rlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavlda
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 4-241 | 1.1e-78 | 259.8 | In-house | 32-270 (273) | alignment | ||
Range on Protein: 4-241
Range on HMM: 32-270/273.0
AAKKRVNKAKNRYANIVTYDHSRVVLeklsNDPHSDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
.|.. || |||| .|. ||||||.| .|..||||||||. | .....||||| . .|||||.|... |||||| |.| ...||.||||..
vallpenkdknrykdilpydhsrvkl....gdggsdyinAsyv.dgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwple
----TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD--SLPGARPWVIHCSAGVGRTGAFLVID
. .| ...|||...|...||..||. .. .| |.|.|...|.| ||| |||.. . .| . ... | .||. | |.||||||||||.|...|
ggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfiald
AMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.|.| .| ..||....|| .|. ||.|||| |||.|.. |.||
llldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 4-241 | 1.8e-77 | 255.8 | In-house | 39-275 (278) | alignment | ||
Range on Protein: 4-241
Range on HMM: 39-275/278.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
|.. || |||| .|. ||||||.|. |..|..||||||||. | |...||||| . .|||||.|... .|||||.| | ...||.||||..
iallpenkdknrykdilpydhsrvklsllggdldsdYinAsyv.dgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwpgg
TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQA
. .| ...|||.|.|...||..||. .. | |.|.|..||.. ||| ||| . .| . ... . . | ..||||||||||.|.... .|.|.
sltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleql
KKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.| ..||... || .|| ||..||| .||.|.. |.||
ekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 4-241 | 6.8e-77 | 254.1 | In-house | 50-287 (297) | alignment | ||
Range on Protein: 4-241
Range on HMM: 50-287/297.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSN-DPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKkKCHQYWPD
|.. .|| |||| .|. ||||||.| . . |..||||||||. || ....||||| . .|||||.|... |||||| |.| . ||.||||.
iallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpe
STSKYCNLRVTLRKTEVFADYIIRTFVMSQvgQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK--DSLPGARPWVIHCSAGVGRTGAFLVIDAML
....| ...|||.|.|. ..|..||. .. |.|.|.....| ||| |||.... .| . ... . .||. .| ..||||||||||.|.... ||
eggtygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylml
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.| .| ..||... || .|| ||..||| .||.|.. |.||
eqlekeggvdvleavkelreqRpgavqtpsqyrflydalle
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 3-241 | 7.6e-77 | 253.2 | In-house | 37-275 (315) | alignment | ||
Range on Protein: 3-241
Range on HMM: 37-275/315.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGsPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
.|....| |||| ||. .|..||.|| . ..|.||||||||.. .| |||||.|| |||||..||. |||.| . || | || |||||
rvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdd.dkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPd
---STSKYCNLRVTLRKTEVFADYIIRTFVMSQvgQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAM
. .. ...|.| ..| .| ..| .|. . | | | |..|| ||||||.. ....| | ... | . . ..|||||||||| .. || .
rkadsvefGsikvellsleadtdgvarklvtrk..seesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidev
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. |.|....||.||.|| .|..||..||| |.| ||. ||||
vaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 10-241 | 2e-76 | 251.9 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 10-241
Range on HMM: 1-235/235.0
NKAKNRYANIVTYDHSRVVLeklSNDPH-SDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP---DSTS
|| |||| .|. ||..|| | ..... ||||||.|.. |. ..|..||||| . .|||||.|||. |||||| | | ...||.|||| . .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
KYCNLRVTLR-KTE-VFADYIIRTFVMSQVGQT-EERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
.| ...|.|. |.. ..|..|.. ... .. |.| |.|.|.| |||.|||. ....| | ||. |.. . | |.|||||||||| |...|..|.|
tygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleq
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
......||....|| .|. ||.|||. |||.|.. |.||
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 10-241 | 2e-76 | 251.9 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 10-241
Range on HMM: 1-235/235.0
NKAKNRYANIVTYDHSRVVLeklSNDPH-SDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP---DSTS
|| |||| .|. ||..|| | ..... ||||||.|.. |. ..|..||||| . .|||||.|||. |||||| | | ...||.|||| . .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
KYCNLRVTLR-KTE-VFADYIIRTFVMSQVGQT-EERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
.| ...|.|. |.. ..|..|.. ... .. |.| |.|.|.| |||.|||. ....| | ||. |.. . | |.|||||||||| |...|..|.|
tygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleq
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
......||....|| .|. ||.|||. |||.|.. |.||
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 4-239 | 2.9e-76 | 251.4 | In-house | 48-293 (306) | alignment | ||
Range on Protein: 4-239
Range on HMM: 48-293/306.0
AAKKRVNKAKNRYANIVTYDHSRVVLEkLSNDPHSDYINASYLR-DYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
..| || |||| ||. .||.||.|. .. | ||||||.|.. . || |.|||||| . |||||.||| ||||.| .| |.|| .||||
egakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPd
STS--KYCNLRVTLRKTEVFADYIIRTFVMSQ-VGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDS--LP--GARPWVIHCSAGVGRTGAFLV
... .| ...|| . . ||||.|....|. ..|||.|.||||..|||.|||. ||| . ..... . | |.| |.|||||.||||.|.|
eeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiv
IDAMLRQAKKQK---TVDIFNYVKAIREDRPHMVQTSEQYVFIHLAV
||..|.. .|.. .|| . || .|| | .||| .|| |.. |.
iDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykai
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 3-241 | 1.3e-74 | 247.1 | In-house | 48-302 (307) | alignment | ||
Range on Protein: 3-241
Range on HMM: 48-302/307.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSND-PHSDYINASYLRDYDG-------SPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKK
..|.. .|| |||| .|. |||.||.| |... ..|||||||| |. .. .....||||| . |||||.|... ||||||.|.| ..
siallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgre
KCHQYWPDS--TSKYCNLRVTLRKTEVFADYIIRTFVMSQV-GQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK--DSLPGARPWVIHCSAGVGR
||.|||||. . | |..|||...|. ..|..||. .. | |.|.|...|.| ||| |||.. .| . ... | ..||. | ..||||||||
kcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgR
TGAFLVIDAMLRQAKKQKT---VDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
||.|.... |||| .|..| ||... || .|| ||..||. |||.|.. |.||
tGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 2-241 | 3.9e-74 | 244.1 | In-house | 32-275 (290) | alignment | ||
Range on Protein: 2-241
Range on HMM: 32-275/290.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGsPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
.||..| .|..|||| .|. ||.|||.|.| .....||||||.... .| ...|||.|| . |||||.|. . ..||. ..| ||||..|||
teagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgveg.kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWp
DSTSK---YCNLRVTLRKTEVFA-DYIIRTFVMSQvgQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVID
... . . ...||| . . . |..|||. . . | |.| |||.|.| |||.|||. |. .| | ... . . | |.||||||||||. ..||
eegeeelefgefevtleeekavdddflirtLkvea..qkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaid
AM---LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. |.. | ....|.|. | .|..|. .||| |||.... ||.|
yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 5-241 | 1e-72 | 239.8 | In-house | 4-241 (245) | alignment | ||
Range on Protein: 5-241
Range on HMM: 4-241/245.0
AKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP-DS
|.. .|| |||| .|. |||.||.| ..|..|||||||| | . .. .||||| . .|||||.|... .||||| . | ...||.|||| ..
allpenkdknrysdilpydhtrvklspdggdldsdyinasyv.dgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplge
TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSL-PGARPWVIHCSAGVGRTGAFLVIDAMLRQ
. .| ...|||...|...||..||. .. .| |.| |..||.. ||| ||| . .| . . . | .. | ..||||||||||.|.... ||.|
sltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleq
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
..| ..|.... || .|. ||..||| .||.|.. |.||
lekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 4-242 | 1.2e-72 | 239.6 | In-house | 45-283 (297) | alignment | ||
Range on Protein: 4-242
Range on HMM: 45-283/297.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGspkAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKkKCHQYWPDS
|.|.|| |.||.||. || ||| |. . .|| |||.|||... . .|.|| |||.|...|. .||||. . |..| || .||.|.
vaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh...rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdk
TS-KYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQ--YATAVLGLRRKITKDSLPGAR-PWVIHCSAGVGRTGAFLVIDAM
.. .. .. |.| .. .| |...... .| | ||.|. |||| |.. |...| | . || | | ..||.||||||| .| || .
gvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsv
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
. .||..|.||||..|| .|..||..||| ||| |.. |||||
vaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlea
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 4-241 | 1.6e-72 | 239.4 | In-house | 5-244 (249) | alignment | ||
Range on Protein: 4-241
Range on HMM: 5-244/249.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP-D
|.. .|| |||| .|. ||||||.|. |.. ..||||||||. |. .....||||| .|||||.|... |||||| | | ..||.|||| .
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyi.dgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplg
STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK--DSLPGARPWVIHCSAGVGRTGAFLVIDAML
.. .| ...|||...||..||..||. .. .. |.|.|.....| ||| |||.. .| . ... | ..|| | ..||||||||||.|.... ||
gsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylml
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.| .| ..||....|| .|. ||..||. |||.|.. |.||
eqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 9-241 | 3e-72 | 238.6 | In-house | 60-289 (319) | alignment | ||
Range on Protein: 9-241
Range on HMM: 60-289/319.0
VNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTglieghKKKCHQYWPDS-TSKY
|| |||. ||...|...| ||.| |||||||.. | ... |||.|| |||||.|. . . ||.|| |.|| |||| |.
qnkdknriinilafdknvvklerliGeefsdyinasfvtGyq.rkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivike
CNLRVTLRKTEVFADYIIRTFVMSQ-VGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKI--TKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAK
. | . | |.|..| . .|. ... | . |.|| |||.|||.|.. .. | .|. .. . .. |.||||||||||...|.|..| . |
erfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmk
KQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
..| ||..|.|. .|..|...|| || ||. |.||
eekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 3-241 | 6e-72 | 237.4 | In-house | 41-284 (307) | alignment | ||
Range on Protein: 3-241
Range on HMM: 41-284/307.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP-
....| |. |||| .|...|. ||.|.|. . .|||||||... |. . | .|| |. . .||||||... .||||. | | .|||..|||
kvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykek.kkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpi
DSTSKYCNLRVTLRKTEVFADYIIRTFVMSQVG-----QTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVI
. . .| .. |.| ..| |||||.. .|... ..| | |||.| |.| ||. |...| | ... . | |.||||||||.| |. .
edevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifval
DAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
| .| | |. ..||||. || .|..|. .|| |||||.. |.|.
dsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralld
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 9-241 | 2e-71 | 235.8 | In-house | 24-253 (284) | alignment | ||
Range on Protein: 9-241
Range on HMM: 24-253/284.0
VNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTglieghKKKCHQYWPDS-TSKY
|| |||. .|...|...| ||.| |||||||.. | ... |||||| |||||.|. . . ||.|| |.|| |||| |.
qnkdknrighilafdknvvklerliGeefsdyinasfitGyq.rkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivike
CNLRVTLRKTEVFADYIIRTFVMSQV-GQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKI--TKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAK
. .| . | ..|..| . .|. ... | . |.|| |||.|||.|.. .. | .|. .. . .. |.||||||||||...|.|..| . |
erfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmk
KQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
..| ||..|.|. .|..|...|| || ||. |.||
eekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 4-242 | 3.8e-71 | 234.9 | In-house | 42-287 (325) | alignment | ||
Range on Protein: 4-242
Range on HMM: 42-287/325.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMM--WQerrCVIVMLTGLIEGHKKKCHQYWP
.| | ||||||. |.|..|.|||||| . .||.|||||||||||. . . ..|.| .|.||.. |. | .|... ... |..| .|||
vamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkk.dvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcavywp
DS---TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD------SLPGARPWVIHCSAGVGRTGA
. . .. |.| || | ..||. | . . || . | | | |... |.| ||... .... . . . . .. | ..||||||||||.
kemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGv
FLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
|. . ..| . .. ||||..|| .|.||| ||.| .||..|. |. ||
fislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 4-241 | 6.3e-71 | 233.8 | In-house | 36-288 (297) | alignment | ||
Range on Protein: 4-241
Range on HMM: 36-288/297.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP--
|.|.|.| ||||.... ||..||||.|...|..||||||... | .||.||||| . |||||.|... |||| | ..| . || ||||
asklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGyk.qkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWple
-DSTSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK-------------DSLPGARPWVIHCSAGV
.|.... .|.|. ..|. || .|......| . |.| | . |. ||| |||. |...| ...|. . | | |.|||||.
eessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGi
GRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
||||.| .| | . ... |||... || .|. | ...|| |||.| .|||||
GrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 10-239 | 8.4e-71 | 233.2 | In-house | 28-264 (274) | alignment | ||
Range on Protein: 10-239
Range on HMM: 28-264/274.0
NKAKNRYANIVTYDHSRVVL-EKLSNDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTS---
.. |||| .|. ..|||.| .. |.|. |.|||| |.. ||. |||.|||| . |||||..||. |||||| | | ...||..|.||...
sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyei
--KYCNLRVTLRKTEVFADYIIRTFVMSQVGQteERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPG-A--RPWVIHCSAGVGRTGAFLVIDAML
.| .. .. .|. || .|..|.... . || |. | .| |||. .|. |...| | ... .. | | |.|||||.||||.|. |. .
serygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiav
RQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAV
|| .....||... | .| || |||||||| .|| |.
rqlreeivvdvlkivcnlrldrGGmvqtseqyelihral
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 8-241 | 4.8e-70 | 230.7 | In-house | 44-281 (290) | alignment | ||
Range on Protein: 8-241
Range on HMM: 44-281/290.0
RVNKAKNRYANIVTYDHSRVVLEKLSNDP--HSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS-T
|| .||.|||| || |..| ..|... .||||.|. .| . |.|||||| . . |||...|||. ..||||| || .|.||.|||||| |
ssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykek.kqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdt
SKYCNLRVTLRKTEVFADYIIRTFVMSQVGQ-TEERYVYQYHFTVWPDKG-VPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
..| . ...| . |.. .||.|.. . . . ... | ||..| |...| |....| .| ... . . .| .. |.|||..|||.. |.... . .
kaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattink
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.|.. .|.|. .| | .| .||| .|| .|. ||.
cktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 4-241 | 5.8e-70 | 230.9 | In-house | 4-240 (243) | alignment | ||
Range on Protein: 4-241
Range on HMM: 4-240/243.0
AAKKRVNKAKNRYANIVTYDHSRVVLeklsnDPhSDYINASYLRDYdgsPKaYIATQGNICINAGD----FWRMMWQERRCVIVMLTGLIEGHKKKCHQY
|.. .|. |||| .|..||||||.| .. ||||||.. . . |. .||||| . | ||||.|... |||||| |.| ..||.||
iallpenlsknrysdilpydhsrvkl.....eg.sdyinanliyvt...pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPDSTsKYCNLRVTLRKTEVFADYIIRTFVMSQVG-QTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD--------SLPGARPWVIHCSAGVGRT
||... | ...||| ..|...||..||.... .. . ..|.|..||.. ||| |||. . .| . ..... |.. .| ..|||||||||
wpgev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GAFLVIDAMLRQAkkqkTVDIFNYVKAIREDRPH-MVQTSEQYVFIHLAVLE
|...... ||.. .||....|| .|| ||. .||| .||.|.. |.||
Gtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 6-241 | 2.4e-69 | 229.1 | In-house | 29-270 (278) | alignment | ||
Range on Protein: 6-241
Range on HMM: 29-270/278.0
KKRVNKAKNRYANIVTYDHSRVVleklsndphsDYINASYLRDYdgsPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST-
.. |..|||| .|. ||||||. |||||||.. | ||..||||| .. |||||.|... ||||||.|.|. ..||.||||..
lylgnldknRykdilpydhsrVk..........dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggs
SKYCNLRVTLRKTEVFADYIIRTFVMSQV----GQTEERYVYQYHFTVWPDKGVPQYA--TAVLGLRRKITKDSL-------------PGARPWVIHCSA
| ...||| ..||. ||..||. . . |.|.|...|.. ||| ||| . . .| | . | . .. | ..||||
ltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsa
GVGRTGAFLVIDAMLRQAkkQKTVDIFNYVKAIREDRPH-MVQTSEQYVFIHLAVLE
||||||.. ... ||.. ...||....|| .|. ||. .||. |||.|.. ..||
GvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyeflle
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 9-241 | 5.9e-67 | 220.6 | In-house | 46-276 (287) | alignment | ||
Range on Protein: 9-241
Range on HMM: 46-276/287.0
VNKAKNRYANIVTYDHSRVVLEklsnDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST-SKY
|| |||...|. .| ||.|. . | |||||... | . ||.|.... .. | .||....... .||||. . | ....|.||||... .
qnkdknRltqilvpdnyrvllk....gehpdyinavfidgyk.ekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvl
CNLRVTLRKTEVFADYIIRTFVMSQVGQ-TEERYVYQYHFTVWPDKG-VPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAKK
. ...| . || |.||.|.. . . .. .... | ||..| |...| |....| .| . ... .. .| . |.|||..|||.. |. .. ....|.
GeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckt
QKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. ..|.|. .| | .|..||| ||| || .|||
eGviDvfqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 4-241 | 1.3e-64 | 212.8 | In-house | 35-273 (280) | alignment | ||
Range on Protein: 4-241
Range on HMM: 35-273/280.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNdphsDYINASYLR-DYDGSP--KAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYW
||.| | .|||| .|..||. || |.. .. |||||.|. . ... . |||||| . | |||.|.|... .||||| |.| ..||||||
aarkpenlsknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyW
PDS--TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDA
|.. ...| ...|...|.. |..| .|... ..||| . | .. |||.|||. .. .| . ... | .| |.|||||.|||| .....
PetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlillet
MLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
| ... | . . |. .|. | .|||..|| |. |.|.
alalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 3-241 | 4.4e-64 | 211.0 | In-house | 49-290 (297) | alignment | ||
Range on Protein: 3-241
Range on HMM: 49-290/297.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
|.||. | |||......|||||| |.. ... .||||||| . | | ||||||| . . |||.|.|.. .|||.|| | | |.|..||||
evakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpd
STSK-YCNLRVTLRKTEVFA-DYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAML
|. | | | ... ||..|.| . .. ..| | | |.|| ||..||| | ..| .|||. | . | |.|||.|.||||....|| .|
eGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvl
RQ-AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. .| | .|| .. .|..||..|.| .|. |. || |
nrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 2-241 | 9e-63 | 207.0 | In-house | 37-234 (392) | alignment | ||
Range on Protein: 2-241
Range on HMM: 37-234/392.0
SEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHkkkchqywp
.|.| .|. |||| ||. || .||.|| . . |.|||.||||.. .| |||||.|| |||||..||. . |.|.| | ||
qtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdne.kayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.........
dstskycnlrvtlrktevfadyiirtfvmsqvGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLR
. | | |.||| ||||.||......| . ... | ..| .||||||||||| . ||...
................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvva
QAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.||| . ||.||.| ||. ||.|||| ||| ||. ||||
hakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 9-240 | 3.4e-61 | 201.6 | In-house | 19-261 (270) | alignment | ||
Range on Protein: 9-240
Range on HMM: 19-261/270.0
VNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSK--
.|. ||||.|. ..||.||.|..|... |||| |.| .||..|.|||..| .||||.|.|. |||.||| | .||| .||| .. .
rgkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv
---YCNLRVTLRKTEVFADYIIRTFVMSQVGqtEERYVYQYHFTVWPDKGVPQYAT------AVLGLRRKI--TKDSLPGARPWVIHCSAGVGRTGAFLV
. ...|. ..| ||.. . . | ||| . .... |||.|||. . .| . |.. ....| | |...|||||||||| ...
kledgkikvlalseekeegyiltrlrleekg..eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlia
IDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
.| ..| ...| ||. . ....|.||. .||..||| |.. ||.
lDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 3-241 | 4.4e-60 | 198.3 | In-house | 30-267 (273) | alignment | ||
Range on Protein: 3-241
Range on HMM: 30-267/273.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNdphsdYINASYLRDYDG-SPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
| .||. ||.|||| |.. ||..|| |.. .. |||||... | |||.|| . . |||.|.|. . ||.|.| |. | |||.|||
evgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywP
DSTSKYC---N-LRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLpGARPWVIHCSAGVGRTGAFLVID
.|..| | |.|.| |.. .. .|.. .... .| | | . .|. ||| |||. |. .| . ... . | | |.|||||.||.|....||
esknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitid
AMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
..| ...| .|. . |. .|| | .|||..||.|.. |.||
vvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 3-241 | 3.5e-57 | 188.3 | In-house | 25-269 (290) | alignment | ||
Range on Protein: 3-241
Range on HMM: 25-269/290.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNdphsDYINASYLrDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD
..||. |...||| .. |||||..||. .| |||||| . . . . || ||| . .. ||.|.|... .||| ..| .. ||.||||
reaklpenrnlnryrdvspydhsrikleradn....dyinaslv.eleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPq
STS------KYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD-SL-PGARPWVIHCSAGVGRTGAFL
. . .|.|.| ..|. |..|.. . .. | | ....|.| ||| |||. .| | . |. . || . | |||||||.||.|.|
geeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfc
VIDAMLRQAKKQKT---VDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
..|..| . .|.. ||| . . ..|. | ..|| .| | .||.||
lvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 7-241 | 6.9e-57 | 187.8 | In-house | 45-277 (439) | alignment | ||
Range on Protein: 7-241
Range on HMM: 45-277/439.0
KRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKkkchqYWPDSTSK
. ...|||| .....||.||.|... ||| |||| |.. | .| |||||| .. ||||...... ||||| |.| .| ||| ..
qeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyy.ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaev
-YCNLRVTLRKTEVFADYIIRTFVM-SQVGQT-EERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK-DSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
| .. | . . .|.|| | . . .| || | |.|.. |||| || |. || . | | . | |.||||||||||. . .| | |
cygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeq
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
| .. ||| || .|..| .|||. |||||. ||||
lklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 6-241 | 2.5e-56 | 185.6 | In-house | 39-278 (288) | alignment | ||
Range on Protein: 6-241
Range on HMM: 39-278/288.0
KKRVNKAKNRYANIVTYDHSRVVLEklsnDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP---D
... |||. .|. |||.||.|. . . ||||||...| .||||. . ..|||.|..... |||||. | .|.|...||| .
iaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkg
STSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITK----DSLPGARPWVIHCSAGVGRTGAFLVIDA
| |. .|.|||.... .. |.. .. .. . . | ..| ||. |||. .| . .. . . | |.||||||||||.| .. |
etvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvya
MLRQAKKQKT-VDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.|. .|.. .|| . |. .||.| .|||..||. | ||||
avrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavle
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 8-239 | 2.2e-55 | 182.5 | In-house | 38-289 (301) | alignment | ||
Range on Protein: 8-239
Range on HMM: 38-289/301.0
RVNKAKNRYANIVTYDHSRVVLEKLSN--DPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST-
||| ||. ||..||. |..|.. .| . .||||||. .| . |..||.|| . ||||..|||. |||.|.| || |.||.||||.|.
eenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysek.kkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnsea
--SKYCNLRVTLRKTEVFADYIIRTFVM-S-------------QVG-QTEERYVYQYHFTVWPDKGV-PQYATAVLGLRRKITKDSLPGARPWVIHCSAG
... .. ||| .. |. |..|| . . .| . . . | |.. | ||. || ....| . . | . .| | |.|||..
eseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdt
VGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAV
|.|.| . .. | |.| . ||.|. .||.| .| .|.| |||..|. ..
VsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvi
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 4-241 | 2.3e-55 | 182.5 | In-house | 27-264 (283) | alignment | ||
Range on Protein: 4-241
Range on HMM: 27-264/283.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLSNdphsDYINASYLR--DYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
| . || |||. .||..| || |. .|. |||||... . . | ||..|. . |||.|...|. . ||||| | |. ..|| ||||
iasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWP
DS-TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEE-RYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAM
. .| .. ||||| .||. ... . . ... . | . | . | ... . . |.. | |.|||.|.|||..|. . |
krGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasas
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. .|. . ||.|. || .||.|. .||| .|| ..| .|||
vkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 5-240 | 8.4e-55 | 180.5 | In-house | 37-287 (296) | alignment | ||
Range on Protein: 5-240
Range on HMM: 37-287/296.0
AKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKkKCHQYWPDS-
. . |. |||. ..| ||. ||||||| . .||||||.| . .|.|| |.. ..|||....| .|.|| . .| ....|||
glrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsfl.kkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks
TSKYCNLRVTLRKTEVFADYIIRTFVMSQV----------GQTEERYVYQYHFTVWPD-KGVPQYATAVLGLRRKIT--KDS---LPGARPWVIHCSAGV
.| .. | . ... .|. |||| . . ..|.| | ....|.|. . || ..|.. |||.. .. | | |...| |.
keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGa
GRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
.|.|..| ||| | ...|.. ||.|..|| .|..||..|.. |.| .| .|
sRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvll
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 3-240 | 1.4e-52 | 173.6 | In-house | 42-293 (300) | alignment | ||
Range on Protein: 3-240
Range on HMM: 42-293/300.0
EAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDpHSDYINASYLRDYDG-SPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP
..|| .|. |||. ... |...|| | .. ...||||| .. | . . ||..|| . . |||.|.|.. .||||| .|. |.|...|.|
staklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfP
DS-----TSKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQ-------YATAVLGLRRKITKDSL--PGARPWVIHCSAGV
.. | .. . .|| . .| .| ... . . ||| |. .| |||.|||. | | .||| .. . | ..||||||
kleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGv
GRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
|||| .. | .. ......|| . .. .|| | ..||| || |.. ...
GrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvli
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 36-241 | 1.6e-49 | 164.3 | In-house | 2-223 (272) | alignment | ||
Range on Protein: 36-241
Range on HMM: 2-223/272.0
PHSDYINASYLRDYdGS---PKAYIATQGNICINAGDFWRMmWQERRCVIVMLTGLIEGHKKKCHQYWP-------------DSTSKYCNLRVTLRKTEV
| |.||||... | |. |.......| ..| ||||. .... .||.|... | . ||..||| . | | .||||| ..|.
plsgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
FADYIIRTFVMSQV-GQTEERYVYQYHFTVWPDKGVPQYAtaVLGLRRKITKdslpgARPWVIHCSAGVGRTGAFLVIDAMLRQAKKQKTVD--------
. |||.|..... . . .| | |...|.| ||| |||| | .| | . . . .| ..|||||..||| . ... .|.. .. ||
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
IFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
....|. .|. ||..||| |||.|.. |.||
leeaveelraqrpgavqteeqylflyealle
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 4-239 | 4.7e-46 | 151.9 | In-house | 32-273 (287) | alignment | ||
Range on Protein: 4-239
Range on HMM: 32-273/287.0
AAKKRVNKAKNRYANIVTYDHSRVVLEKLsNDPHSDYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
||.. . |||||... .|..||.| . . |||||| |. | .|.||.|| | .||||.....| ......| .| ..||..|||.
aaeelaavkknryadvlPiddtrvllsae.gelGsdyinanyvasytdd.eafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer
tSKYCNL---R-VTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQY----ATAVLGLRRKIT-KDSLPGARPWVIHCSAGVGRTGAFL
. . | | .. .| .|.. . .. | | | |... ||||... . || ...| . . .. | |.|...|.||.| .|
.evPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGill
VIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAV
. ..... .. ||. . | .|| | .||. |. .. |.
atlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyeal
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 10-241 | 5.5e-45 | 148.5 | In-house | 1-169 (182) | alignment | ||
Range on Protein: 10-241
Range on HMM: 1-169/182.0
NKAKNRYANIVTYDHSRvvleklsndpHSDYINASYLRDYDGSPKaYIATQGNICINAGDFWRMMWQERRCVIVMLTglieghkkkCHQYWPdstskycn
|. |||| .|. ||||| ..|||||.... . . . .|||||. . ||.||..... .||.|| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywp........
lrvtlrktevfadyiirtfvmsqvgQTEERYVYQYHFTVWPDKGVPQyATAVLGLRRKITKdslpGARPWVIHCSAGVGRTGAFLVIDAMLRQakkqkTV
. .||...||... ||| ||| .| . ... . .| ..||||||||||.. ... |... |
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gv
DIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
.... || .|. ||.||.| .||.|..||.||
sleeavklvrsrRpgmvitpnqyfflqlalle
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 10-240 | 2.9e-43 | 142.6 | In-house | 56-280 (290) | alignment | ||
Range on Protein: 10-240
Range on HMM: 56-280/290.0
NKAKNRYANIVTYDHSRVVLeklSNDPHSDYINASYLRdydGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSK---
. |||| ..| | .||.| .. . ||. | |.. | .| ||| . . |.|||. ||. .|||| ||| | ||.||.|. .
efkknrykdvvcndktrvil...kdGydGdyvhanyvk...GlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevlt
YCNLRVTLR-KTEVFADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSlpGarPWVIHCSAGVGRTGAFLVIDAMLRQAKK
. .. |. ... |. | .|. . .. . | .. .. |||| |.. . |.| . | . | | | | |.|||||.||||.| |.. |. .
fGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkas..G..pvvvhcsaGiGrtGtfvaievglqilld
QKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
| .|. . |.|.|. | || ||. . ..|
Gkeldlldlvralrnsrlnsvqvdiqylalveill
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 10-238 | 2.1e-42 | 140.0 | In-house | 33-254 (267) | alignment | ||
Range on Protein: 10-238
Range on HMM: 33-254/267.0
NKAKNRYANIVTYDHSRVVLEKLSNDphsdYINASYLRDYDGSpKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHkkkCHQYWPDS---TSK
|...||. . . ||..||.| . .. ||||||. | .|.|.||. . .||. .. ... |||.|| .. ...|| . |
nqernrlddnlpyddtrvilrtkeee....yinasyvegyktk.nafivtqdplkntitdfltvihdqkvpvivlltkvftdn...irlfwPPkmgqakk
YCNLRVTLRKTEVFADYIIRTFVMSQVGQtEERYVYQYHFTVWPDK-GVPQYATAVLGLRRKITKDSlpGARPWVIHCSAGVGRTGAFLVIDAMLRQAKK
| .| | . || | |. . . . | |.. | . | ..|. | . | || |..||.||||.|.|||||..|..||.
yqdltvehslekeendyqiitlelkfkne.sahnvtlyyykkwnintnnkpylkplfgilaknqlen..gnrPlvvacsdGvGrsGtflvidsqlerakt
QKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLA
. ..|||.... ||. |. .|.| |.|..||
egvsdifdflrkirsqriglvdtkeryiyihel
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 38-236 | 1.1e-41 | 137.7 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 38-236
Range on HMM: 2-163/174.0
SDYINASYLRDYDGSPkAYIATQGNICinagdFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDstskycnlrvtlrktevfadyiirtfvmsqVGQTE
|||||||.| . .| .||.|| . ||.|..... ..|||. ..| .. ||..|||. . .
sdyinaspldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredl
ERYVYQYHFTVWPDKGVPQYATaVLGLRRKITKDSLP-GARPWVIHCSAGVGRTGAFLVIDAMLRQAKkQKTVDIFNYVKAIREDRPHMVQTSEQYVFIH
||...||... ||| ||| .. .| . . . . . . .| ..||||||||||.. ... |||. . ...||....|...| ||.|||| .|| |..
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 31-240 | 1.9e-40 | 133.8 | In-house | 5-170 (176) | alignment | ||
Range on Protein: 31-240
Range on HMM: 5-170/176.0
KLSNDPHSDYINASYLRDYdgspkAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSKYCnlrvtlrktevfadyiirtfvm
.| |...|||||... . ..|||||... . ||..|..... ..|.|| ..| .. ||..|||. .. .
llgldldldyinanlilgs.....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi......................
sqvgqteeryvyQYHFTVWPDKGVPQYaTAVLGLRRKITKDSLPGaRPWVIHCSAGVGRTGAFLVIDAMLRqakkQKTVDIFNYVKAIREDRP-HMVQTS
||... ||| |||.. ...| | . | . | .| ..|||||.||||...... . . .| ..... .. .|| || ..|||
............qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtp
EQYVFIHLAVL
||| |.. ..|
eQyrflyefel
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 6-240 | 2.3e-39 | 129.8 | In-house | 33-266 (281) | alignment | ||
Range on Protein: 6-240
Range on HMM: 33-266/281.0
KKRVNKAKNRYANIVTYDHSRVVLEK-LSNDPHSDYINASYLRDYdGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST
.. ||. ||||.|| | ||| |. . | .||| | |.| . || ||| |||||.||| |||| ..| ..|| .|.| .
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirsp.flkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprna
---SKYCNLRVTLRKTEVFADYIIRTFVMSQVGqtEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPgarpWVIHCSAGVGRTGAFLVIDAMLR
.. .| |. . | . . .| | | | . .. . ||| ||. . .| . ||| | | ||||||||||.|... .. |.
hcclqfdklsvsyedstvnkslvttrlnlsyeg..etrlithwlwkewpdwqvpessevmlkilrkirarstp....pvihcsagvgrsgtlmaveialq
QAKKQKTV-DIFNYVKAIRE-DRPHMVQTSEQYVFIHLAVL
. . |. || . | .| | ||| .||..| .|
sihshftlpdikqivshlrvtgraasvqtlqqymliwkvll
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 8-241 | 2e-38 | 127.1 | In-house | 39-275 (307) | alignment | ||
Range on Protein: 8-241
Range on HMM: 39-275/307.0
RVNKAKNRYANIVTYDHSRVVLEKlsNDPHSDYINASYLRdYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST---
. | |||| .. |..|.|.. . |||| | || || .|..|| .|| |. ||. ..|| .|| | ||.||||
santdknryqdvkcqdkgrivvkf..dglasdyihanylg.iaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqk
SKYCNLRVTLRKTEV------FADYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSlpgaRPWVIHCSAGVGRTGAFLVIDA
... |. ... . .| . . . | . .. .. |||.|||| . . | . | | |.||||||||.|. . |
lvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydt....npvvvhcsaGvGrsGtivaisl
MLRQ-AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. . . . |. . |. .|..|.. .|| ||...| .||
vqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlle
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 5-241 | 4.3e-37 | 123.9 | In-house | 41-278 (314) | alignment | ||
Range on Protein: 5-241
Range on HMM: 41-278/314.0
AKKRVNKAKNRYANIVTYDhSRVVLEKLSNDPhSDYINASYLRDYdgspKAYIATQGNICINAGDF----------WRMM--WQERRCVIVM--------
|.. .|. |||| .|. .| .||.| .|... ||||||||.. . ...||||| |. || |||. .. . .|||
adlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlad
-------------LTGLIEGHkkkchQYWpdSTSKY---CnlrvtlrktevfadY-------IirtfvmsqvgqteERYVYQYHFTVWPDKGVPqYATAV
|..| ... .. . . . . ||....|. . .|| ..| .
elsrLdaAlgKtpllildgng.....nep..taadlellk..............eelydpelf.............erlgikylripvpDgsap.lledf
LGLRRKITKDslPGARPWVIHCSAGVGRTGAFLVIDAMLRQAKKqKTVDIFNYVKAIRE--DRPHMVQTSEQYVFIHLAVLE
. . . | . . .| ..||.||.|||| |.|.. .... . .....|...| .|..... |||.||. |.||
deflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRpinpnpgfieqleqyefilealle
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 35-236 | 5.1e-37 | 122.6 | In-house | 2-154 (172) | alignment | ||
Range on Protein: 35-236
Range on HMM: 2-154/172.0
DPHSDYINASYLRDYDgSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLieghkkkchqywpdstskycnlrvtlrktevfadyiirtfvmSQVG
|..||||||||| | |. .||||| . . |||||.... .||.||.| .
degsdyinasyldlyy.ipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydp
QTEERYVYQYHFTVWPDKGVPqYATAVLGLRRKITK-DSLPGARPWVIHCSAGVGRTGAFLVIDAMLrqakkqKTVDIFNYVKAIREDRPHMVQTSEQYV
. .||...||... ||| ||| . .| . . | . | | ..||||||||||.. ... || . ..... |. .|| ||..||. .||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
FIH
|..
fly
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 4-240 | 5.8e-37 | 122.1 | In-house | 42-284 (305) | alignment | ||
Range on Protein: 4-240
Range on HMM: 42-284/305.0
AAKKRVNKAKNRYANIVTYDHSRVVLEklSNDPHsDYINASYLRDyDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
| |. .. |||| .. |. || || . || .|| | |. || .| || . ||| | .|.. | || |.| |||..|..
afkeaqeagknrykdvgcldnnrvkle..gpwph.eyihanyvst.ptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfask
TSKYCNLRVTLRKTEV---------FA----DYIIRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKitkdSLPGARPWVIHCSAGVGRT
. ... .| | | . .| .. . .. | | .||. |||.||| .|.| | | . | | |.|||||.|||
dkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellek....arpskgpivvhcsagigrt
GAFLVIDAMLRQAKKQKTVDIF-NYVKAIREDRPHMVQTSEQYVFIHLAVL
|. .... .| | . .. .. |||.| .|| .||.|.| .|
gsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvil
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 51-236 | 4.7e-36 | 119.1 | In-house | 6-143 (152) | alignment | ||
Range on Protein: 51-236
Range on HMM: 6-143/152.0
GSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWpdstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyQYHFTVWP
. |...||||| . .. |||||... .||||| | | .| ||.||. ||... ||
ampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qylhlpwp
DKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLrqakkqKTVDIFNYVKAIREDRPHMVQTSEQYVFIH
| |||. . .| | . | | | | ..||||||||||.. ... || . |.....|. .|| ||..|.. .|. |..
DhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 8-240 | 4.9e-36 | 118.9 | In-house | 53-286 (305) | alignment | ||
Range on Protein: 8-240
Range on HMM: 53-286/305.0
RVNKAKNRYANIVTYDHSRVVLEKLSndpHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSKY
....||||... |.| | |.| | |||| | |. | .|..|| . .|| |. |.. |||| .| | || |||| . .
diaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgek
CNLRVTLRKTEVF--------ADYIIRTFVMSQVGQtEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLpgarPWVIHCSAGVGRTGAFLVIDAM
.|. . .| |. | .. .. |. .. | . ..| |||.||| . | | | . | |.|||||.||||. . |. .
lelksgivvenvsgskpmerdaeiqitllnltysgd.qkmsvrhlqwtewpdrgvppckltslellsairgskv....pivvhcsagigrtgtivaieyi
LRQAKK-QKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
| . . .. . . |||.|..| . .|. ||.||| .|
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvml
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 9-241 | 1.3e-35 | 117.8 | In-house | 34-268 (285) | alignment | ||
Range on Protein: 9-241
Range on HMM: 34-268/285.0
VNKAKNRYANIVTYDHSRVVLEKLsndpHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST---S
| ||||.. . .||||.. ||| ||..| .||.||| . |||.|..||. . ..|| |.|| .|| |.|.
anpdlnryadvrcieetrvvlknh....drdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevv
KYCNLRVTLR--KTEVFADYIIRTFVMSQVGQTEERYVYQYHF--TVWPDKGVPQYATAVLGLRRKItKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLR
|. . .|| | | | |. .. . . .. .| | |||. |. | .. | . . | | .| ..||||||||| .|. ||
kfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwv.kkvnpkekpicvhcsagvgrtatfvgidyati
QAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. .. ..... |. .| | . ||. |..|... ..|
rimenpniemldivremramrfqavqshmqflflyvvlme
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 10-164 | 3.5e-35 | 116.2 | In-house | 28-186 (319) | alignment | ||
Range on Protein: 10-164
Range on HMM: 28-186/319.0
NKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP-----DST
| |.|..|.| ..||||.. ..|... |..|||.| || .| |||.| . . ||||..|. . ||| || | | |.| .|.| |.|
skdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnt
SKYCNLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVYQYHFtVWPDKGVPQYATAVLGL
| | ...|||.. || |.| |... .| . | | . | . |.. .|| .|.. .
slyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliam
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 5-202 | 1.1e-34 | 114.9 | In-house | 42-255 (418) | alignment | ||
Range on Protein: 5-202
Range on HMM: 42-255/418.0
AKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRdyDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST
|. | .||||.||. .|.|| |.|. . |||||| |. || .|.||| . |||||.|..| .||||. | . || .|||.
gdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyid..gaypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqi
SKyCNLRVTLRKTEVFADYII-------------RTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD---SLPG---ARPWVIHCSA
.. . ||| | . | . . | | . ||.. |||. .|... . | . ||. .| | ..||||
gg.eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsa
GVGRTGAFLVIDAMLRQ
||||||.| |...
gvgrtgtfctavimmkk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 22-237 | 2.3e-33 | 110.7 | In-house | 2-165 (178) | alignment | ||
Range on Protein: 22-237
Range on HMM: 2-165/178.0
YDHSRVVLEKLSNDPHSDYINASYLRDYdgspkAYIATQGNicinaGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSkycnlrvtlrktevfa
.|..||.|..|.. . |||||||. .. |...... |........ .||.||. .|... ||..|||....
ldrtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
dyiirtfvmsqvgqteeryvYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQakkqkTVDIFNYVKAIRED
.||... .|| |||. .| . . | . . .| ..||||||||.|.. ... |... ..... .. .||
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RPhMVQTSEQYVFIHL
|| .|.. .|. ....
Rp.ivpnpgqlrqLye
|
|||||||||
PTPc_DSPc_SM00012 | 141-241 | 1.4e-32 | 107.4 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 141-241
Range on HMM: 2-105/105.0
VYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGA--RPWVIHCSAGVGRTGAFLVIDAMLRQAKKQ-KTVDIFNYVKAIREDRPHMVQTSEQYVFIHL
|..||.| |||.|||......| | |.. | . | |.|||||||||| | ..| .|.| .|. |.||||..||..|. ||.|||| |||.|..
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVLE
|.||
alle
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 36-240 | 1.6e-32 | 107.6 | In-house | 1-150 (151) | alignment | ||
Range on Protein: 36-240
Range on HMM: 1-150/151.0
PHSDYINASYLRDYdgspkaYIATQGNicinAGDFWRMMWQERRCVIVMLTGLIEGHkkKCHQYWPDSTskycnlrvtlrktevfadyiirtfvmsqvgq
|.|||||.||. .. .....| ||....... .||.|... | .|..|.|.
plsdyinfsyvtgg......lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg...............................
teeRYVYQYHFTVWPDKGVPQYATAVLGLRRKITKdslPGARPWVIHCSAGVGRTGAFLVIDAMLRQakkqktVDIFNYVKAIREDRPHMVQTSEQYVFI
. |...... ||| |.|.. ||| . ... . .. | ..|||||.||||.. ... ||.. |... .. .|. ||..||...|..|.
...ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
HLAVL
..|.|
lfall
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 10-238 | 8.8e-32 | 105.0 | In-house | 50-276 (301) | alignment | ||
Range on Protein: 10-238
Range on HMM: 50-276/301.0
NKAKNRYANIVTYDHSRVvlEKLSN----DPHSDYINASylrdydGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTS
.| |.|| .. .. | | ... |...|..| | |. .||||| . . ||| |. | ||||. .| ...||..| | ..|
pkdkhryptvPckPstav..evivdGkrvPihanwipts......GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis
KYCNL---RVTLRKTE-VFADYII-RTF-VMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRrKITKDSlpgARPWVIHCSAGVGRTGAFLVIDAM
. .. .......| .. . |. ||. | |. . | | | .. |.|.|||. . . | .. |.| .| |.|||||.||. ||. . .
ekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlm.elvkks...ekPivvhcsaGiGrsvafigteyl
LRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLA
|. . ..|... . .| .||.| . ||| .| .. |
areveadptieltealkhlrehrwngvqtnsqlywmtlG
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 10-241 | 3.6e-31 | 103.3 | In-house | 43-269 (288) | alignment | ||
Range on Protein: 10-241
Range on HMM: 43-269/288.0
NKAKNRYANIVTYDHSRVVLEklsNDPHSdYINASYLRdYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSKYCN
| ...|| |. | .|| |. .||. ||.| . .. | .| . . .|.|. .. ||||. |.| |.| .|.| .
nptrdryenlprcditrvkls...ddpdf.yiaanvvs.sakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
LRVTLRKTEVFADYIIRTFVMSQVGQTE---ER-YVYQYHFTVWPDKGVPQYATAVLGLRRKItkDSLpgARPWVIHCSAGVGRTGAFLVIDAMLRQAKK
.. . . . | .. ..| . .. |. .| . |. |.|.|||. . | | . || .| |.|.||||||||.. .| .|....
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl..ksl..qkPivvhssaGvGrtgtlililialeslrl
QKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. . | . .. ||.| . .|| ||...| |||
ddflgirsllaklreerfkaiqtemqylyvhrcvle
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 121-241 | 9.2e-31 | 101.6 | In-house | 75-192 (440) | alignment | ||
Range on Protein: 121-241
Range on HMM: 75-192/440.0
ADYIIRTFVmsqvGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKD-SLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIR
.||| ... | | . |||. |||||||..| || . . . . | | ..|||||.|||| ...|..||.||. .|||......|
sdyinasyi....ngiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmr
EDRPHMVQTSEQYVFIHLAVLE
..||.|||| |||.|.| ||||
nnrpqmvqtpeqyafvheavle
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 10-238 | 1.6e-29 | 97.5 | In-house | 52-285 (310) | alignment | ||
Range on Protein: 10-238
Range on HMM: 52-285/310.0
NKAKNRYANIVTYDHSRVVLeKLSNDPHSDYINASYLRDyDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD--STSKY
. ||||...| | ||| | |. . . ||| | |.. . ...| .|| . |||||..||| |..| | . || ||| | |
ymhknrysdvvcldtsrvkl.kidksryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtety
CNLRVTLRK--TEVF-ADYIIRTFVMSQVG------QTEERYVYQYHFTVWPDKGVPQYATAVLGLRrKITKdSLPGarPWVIHCSAGVGRTGAFLVIDA
.||| .| | . ||| .| . .| | .. |||.|||. . | ... | | |.|||||..|... . ..
gcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqr.llaq.vrhg..pcvvhcsagkdrlyvvvalkl
MLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLA
. .... . ||. . . .. .| .|| ||..|.
kidkldrglkvdaeevktellksraiciqtelqyliidrv
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 11-241 | 3.6e-28 | 93.2 | In-house | 44-274 (312) | alignment | ||
Range on Protein: 11-241
Range on HMM: 44-274/312.0
KAKNRYANIVTYDHSRVVLEKlsnDpHSDYINASYLRdYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTsKYCNL
| ||| || .| | | | || | ... |. ...||| . . ||.. . |..|.|..| .|| .| | . .|
kdlnrypniqcwdrgrftlag...d.enfyihanfvk.ictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdiv.gfvdl
RVTLRKTEVFA---------DYIIRTF---VMSQVGQteERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSlpgaRPWVIHCSAGVGRTGAFLVIDA
|| . | | |. || | . .| .. |||.|.|. . | | . || .| . ||||||||||.. .|..
edhrvyteycteieiggkskdkithrvlkvvvkatgq..esklnhyqwaswpdhgmpdscdtalrllsavkkdk....kpviahcsagvgrtgtlalies
M---LRQAKKQKTVDIFNYvkaIREDRPHMVQTSEQYVFIHLAVLE
| ||. .||. |.| .| || |.. |||. .|||
miaalrhprkqnvkdsfvl...lrkdrarsvrvfpqyvyalrcvle
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 5-156 | 8.7e-26 | 85.4 | In-house | 28-181 (297) | alignment | ||
Range on Protein: 5-156
Range on HMM: 28-181/297.0
AKKRVNKAKNRYANIVTYDHSRVVLEKlsNDPHSDYINASYLRDYD-GSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDS
||. |||| .|...| .|| | . . .||||| |. | .. || .|| . |||...... ||||.. | |. ..|| |||..
akrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsv
TSKYCN-LRVTLRKTEV----FADYIIrTfVMSQVGQTEERYVYQYHFTVWPDKGVPQ
. . | . | |. | . . ..|.|.| | |||.|||
vqerlkagdvvveflsstsdefdrvil.t.elqliyrsesrvvrhvqflswpdhGvps
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 10-240 | 4e-25 | 82.8 | In-house | 51-282 (302) | alignment | ||
Range on Protein: 10-240
Range on HMM: 51-282/302.0
NKAKNRYANIVTYDHSRVVLEKlsnDPhSDYINASYLRDYDGSPKAYIATQGNICIN--AGDFWRMMWQERRCVIVMLTGLIEGHKkKCHQYWP---DST
| .||. .. .|. .| ||. | .|.||| . . ... ..| . . .||||..||. .|.| | | .| ....| ..
nlkknqsedvpildsnlvklea...ep.dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdy
SKYCNLRVTLRKTEVFADYIiRTFVMSQV--GQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQ
..| ...| || | . .|. . | .. . |..| |..| ||. ... |. . . .. . || |.|| ||||. . . .
keygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavavek
AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
.|.| . | . ||.||..||..|.. .|||....|.|
lqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_egg_pd | Subfamily egg | 9-240 | 4.2e-24 | 79.8 | In-house | 39-267 (307) | alignment | ||
Range on Protein: 9-240
Range on HMM: 39-267/307.0
VNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRdydGSP--KAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGhkKKCHQYWPDSTSK
|. | | . | ||| || |.| | ... | | .| .| . |||||..||. ||||| | ..|. ||| . |.
nnlekarskrvhckdssrvklelrrGqylddfihanrvk...Gkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesd
YC-----NLRVTLRKTEVFADYIIRTFVMSQVGQ-TEERYVYQYHFTvWPDKGVPQYATAVLGLRRKITKdslpgarPWVIHCSAGVGRTGAFLVIDAML
.||.. | . || . | . || |||.. . . . . || . |...| | |... || ...... |. |
slvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqgd.vnnssdvysplrvlrklrnlsk.......pvvvqdilGvskaatlvaieial
RQAKKQK--TVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVL
. . . . |. .| |. |.. .|.|.. ||
lsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 114-239 | 1.6e-23 | 78.4 | In-house | 19-139 (145) | alignment | ||
Range on Protein: 114-239
Range on HMM: 19-139/145.0
LRKTEVFADYIIRT-FVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGaRPWVIHCSAGVGRTGAFLVIDAMLRqakkqKTVDIF
.. | ..|. |.| . .. . .||...||... ||| |||. . .| . . | . | .| ..||||||||||.. ... ||. . |...
aldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsle
NYVKAIREDRPHMVQTSEQYVFIHLAV
. .. .|. ||..|.. .|. |.....
ealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 125-237 | 2.8e-23 | 77.6 | In-house | 33-139 (144) | alignment | ||
Range on Protein: 125-237
Range on HMM: 33-139/144.0
IRTFVMSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPGaRPWVIHCSAGVGRTGAFLVIDAMLrqakKQKtVDIFNYVKAIREDRPH
. ... . . .||...||... ||| |||.... .| . . | . .| .| ..||||||||||.. ... |. |.. ..... .. .|. ||.
vinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpg
MVQTSEQYVFIHL
.|.. .|. |...
avpnpgqlrfLle
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 54-236 | 6.2e-23 | 76.0 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 54-236
Range on HMM: 4-196/198.0
KAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD---STSKYCNLRVTLRKTEVFADYIIRTFVMSQV--GQTEERYVYQYHFTV
. ||||| . |||.|.|. |||. .. ||| .|.|| .| || . . .|| | ...... | . .| ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYATAV---LGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAKKQKT--VDIFNYVKAIREDRPHMVQTSEQYVFIH
| .| |. | | . | | | ..||| | | || |. .| .| .. || ||.|. | .|. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 54-236 | 6.3e-23 | 76.0 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 54-236
Range on HMM: 5-197/199.0
KAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPD---STSKYCNLRVTLRKTEVFADYIIRTFVMSQV--GQTEERYVYQYHFTV
. ||||| . |||.|.|. |||. .. ||| .|.|| .| || . . .|| | ...... | . .| ||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYATAV---LGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAKKQKT--VDIFNYVKAIREDRPHMVQTSEQYVFIH
| .| |. | | . | | | ..||| | | || |. .| .| .. || ||.|. | .|. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 67-240 | 8.3e-23 | 75.8 | In-house | 41-218 (255) | alignment | ||
Range on Protein: 67-240
Range on HMM: 41-218/255.0
AGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP---DSTSKYCNLRVTLRKteVFADYIIRTFV-MSQVG-QTEERYVYQYHFTVWPDKGVPQYATAV
|.... | . |.|||. . | ..||..|.| | |. .. || | || ..|| . .|..| . . . | |... |..| |. | .
vdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelarei
LGLRRkITKDSlpgaRPWVIHCSAGVGRTGAFLVID----AMLRQAKKQKTVDIfNYV---KAIREDRPHMVQTSEQYVFIHLAVL
| . . . .|| .. |.|||.|.||. || ... |.|. .. .||.. .|. . .|. |. ..| | | | ||
lnilk.vvrds....ksvvvhCstGiGrsaafvlaelvyqkmirsldttetvel.dylslleelrskrkraihtPlqlafsilmvl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 11-113 | 1.9e-22 | 74.4 | In-house | 48-163 (350) | alignment | ||
Range on Protein: 11-113
Range on HMM: 48-163/350.0
KAKNRYANIVTYDHSRVVLEKLSND--------PHSDYINASYLRDY----DGSPKA-YIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCH
||||| ||. |.|||| |.| . .|||||.||. . |. |||||. . ||.... . ||..|| ..| .||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
QYWPDSTSKYCNLRVT
.||.. . . .....
rYWqegsydditvkla
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 10-238 | 4.6e-20 | 66.4 | In-house | 47-274 (303) | alignment | ||
Range on Protein: 10-238
Range on HMM: 47-274/303.0
NKAKNRYANIVTYDHSRVVLEklsNdphSDYINASYLrDYDGSPKAyIATQGNICINAGDFWRMMWQER-RCVIVMLTGlIEGHKKKCHQYWPDSTS--K
| |||..... |||.| | . | || |||| . | | || | || . | |||.|. ... .||...|| | .| . .| |
nmdknrfvdvicldhskvkls...d...ssyihasyl.eldsskka.iltqlplshtaadfwqmiieqkvkcvlllltd.seydklggdsvfprnqdflk
Y--CNLRVT-LRKTEVFADYIIRtfVMSQVGQTEERYVYQYHFTVWPDKGVPQY-----ATAVLGLRRKITKDSlpGARPWVIHCSAGVGRTGAFLVID-
. .|| ... |. . .. |.| . ... .|. || . .| . |. . | | ..| | .|.||.|.| ...
feersirvgefkrvelgdgwvlk..vlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkys..dstptvymslsgcgragtfalfet
AMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLA
| | ..| ..|. . .. .|. | | || |. ...
ahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytl
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 69-240 | 9.6e-20 | 65.6 | In-house | 49-224 (263) | alignment | ||
Range on Protein: 69-240
Range on HMM: 49-224/263.0
DFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWP---DSTSKYCNLRVTlrKTEVFADYIIRTFVMSQ-VG-QTEERYVYQYHFTVWPDKGVPQYATAVLG
|.... | . |.|||. | ..|| .|.| | |. |. |. |.| | ...| .. . .| . . . | .| .. |..| |. | .|
kfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvc..ttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelareiln
LRrKITKDSlpgaRPWVIHCSAGVGRTGAFLVID----AMLRQAKKQKTVDIfNYV---KAIREDRPHMVQTSEQYVFIHLAVL
. |....| .. |.|||.|.||. || |.. |.|. .. .||.. .|. . .|. |. ..| | | | ||
il.kvarns....kslvvhcstGiGrsaafsvaElvyqkmirsldttstvel.dylsLleelrssrkraihtPmqLafsilmvL
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 69-239 | 1.4e-18 | 61.4 | In-house | 106-284 (302) | alignment | ||
Range on Protein: 69-239
Range on HMM: 106-284/302.0
DFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDSTSKYCNL-RVTLRKTEV------FADyiIRTFVMSQVGQTE-------ERYVYQYHFTVWPDKGV
.| .. | . ...| |....|...||| .|. | . .. | |.. .| |.| ..|.. .| .. .. | .|. |||.|
khwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftd..kksfklytveiknekkkkkvkktvdilafsawpdhGa
PQYATAVLGLRRKItkDSLpgARPWVIHCSAGVGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAV
|. | . | . . .| . ..||||||||||... | . .|.|. |. . |. .|. | ||. .| ... | |
pkeaytaldilkfc..esy..kknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcv
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 180-242 | 1.7e-18 | 60.7 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 180-242
Range on HMM: 2-64/69.0
VIHCSAGVGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
|.|||.| ||||.|. | . . | .| ||||| |. .| || || .|.||| |. ||
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 180-242 | 7.8e-18 | 58.6 | In-house | 1-63 (69) | alignment | ||
Range on Protein: 180-242
Range on HMM: 1-63/69.0
VIHCSAGVGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLEA
|.|||.| ||||.|. | . . | .| ||||| |. .| || || ..|.||| |. ||
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 13-239 | 3.7e-17 | 57.4 | In-house | 22-255 (290) | alignment | ||
Range on Protein: 13-239
Range on HMM: 22-255/290.0
KNRYANIVtYDHSRVVLEKLSNDPHSDYINASYLRDYDGspKAYIATQGNICIN-------AGDFWRMMWQERRCVIVMLTGLIEGHKK----KCHQYWP
..|... . ..||||. . .||| |... .| . |.|| . . .|| |. ||. .||| | ... | .| |
dqRlevpL.veatrvvLkgygkrfnddyiHAnrvtcpng..lrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvp
DSTS---KYCNLRVTLRKTEVFADYIIRTFVMsQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSlpgaRPWVIHCSAGVGRTGAFLVIDA
.| |. .| | . | | ..|. |. . .. || | . . | . |.. .| | .|. . | ..|| |. | |. |.
esvgeelkfkgltvkCkskekeddvetRelvv.kfddeeeftvtHsllkgWnklnvqedtktllsliqkvkask....tpvivHcvdGiSrsAalaaiil
MLRQ-AKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAV
|.... | . . .||.|. | ..... ... |. ..
gyQkiaetsgsvkledvlkalrkqralaitsalelafvdagi
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 164-241 | 2.6e-15 | 51.1 | In-house | 216-293 (297) | alignment | ||
Range on Protein: 164-241
Range on HMM: 216-293/297.0
LRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
|. . . | . ..||||||||.| . |..| . .|.. |. .. .|| |. .||| ||. ... |||.
lqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 178-237 | 4e-15 | 50.3 | In-house | 249-309 (319) | alignment | ||
Range on Protein: 178-237
Range on HMM: 249-309/319.0
PWVIHCSAGVGRTGAFLVIDAMLRQAKKQ-KTVDIFNYVKAIREDRPHMVQTSEQYVFIHL
| |.||| |||||| . | .|. .. ..||| . | .|.|| . |.| ||| ||.
PlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiyk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 11-120 | 5.7e-14 | 46.2 | In-house | 49-171 (349) | alignment | ||
Range on Protein: 11-120
Range on HMM: 49-171/349.0
KAKNRYANIVTYDHSRVVLEKLSNDPH--------------SDYINASYLRDYDGSP-KAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKK
||||| .|. |.||||.|.| . .. ||||| ||. |. | ||||| . ||.... .. ... |. | .|
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CHQYWPDstSKYCNLRVTLRKTEVF
|..|| . .| | .| |. . .
cdiywqe..lsysnitvklqnssly
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1-48 | 1.4e-12 | 41.7 | In-house | 38-85 (440) | alignment | ||
Range on Protein: 1-48
Range on HMM: 38-85/440.0
PSEAAKKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINASYLRD
||. | || |||| ||..||||||.||.. |.||||||||.
psdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
|||||||||
subfamily_eak_pd | Subfamily eak | 6-164 | 2.4e-12 | 40.9 | In-house | 47-203 (332) | alignment | ||
Range on Protein: 6-164
Range on HMM: 47-203/332.0
KKRVNKAKNRYANIVTYDHSRVVLEKLSNDPhSDYINASyLRDYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIVMLTGLIEGHKKKCHQYWPDST-
.|... . .|| ||. | | .. ||||| | .. . || | . ||.|. ... ||.| .| . .| .|.|| |
tarleavnrnvvkivpydrylvrltssqlnr.lGyinas.laefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktr
--SKYCNLRVTLRKTeVFA-DYIIRTFVMSQvGQtEERYVYQYHFTVWPDKGVPQYATaVLGL
|. | |. .. | . | ...|. | | |. |.. | . .|.| | |
eelkfGildverkef.vkrniletrllelsk.Gn.ethrvlhykvfGwtettlpkyed.flal
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 141-239 | 3.6e-12 | 40.7 | In-house | 217-340 (350) | alignment | ||
Range on Protein: 141-239
Range on HMM: 217-340/350.0
VYQYHFTVWPDKG---VPQYATAVLGLRRKITKDSL-------PGARPWVIHCSAGVGRTGAFLVIDAMLR----------QAK----KQKTVD-IFNYV
||| .. |.| . |. .| . .. | . | ..|||||||||| .. .| .| . . .|| | |. |
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv
KAIREDRPHMVQTSEQYVFIHLAV
. .|. | |||. .|..||. |.
nelrkqrismvqnldqfifiYeal
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 6-158 | 1.3e-09 | 31.2 | In-house | 23-158 (169) | alignment | ||
Range on Protein: 6-158
Range on HMM: 23-158/169.0
KKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINAsylrdydgspkayiatqgnicinagdfwRMMWQERRCVIVMLTGLIEGH----KKKCHQYWP
. .|..||| | .. | || |... .| |||||| ||.|. |||.| . . .|. .| |
eltcnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlgdtddknnfwpekedyqlhp
DST--SKYC-NLRVTLRKTEVFADYIIRTFVMSQVGQTEERYVY----QYHFTVWPDKGVPQYA
| | | | .. .. . | .| | . .. | .|...||..||||
avilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqsp
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 6-157 | 2.6e-09 | 30.1 | In-house | 22-156 (169) | alignment | ||
Range on Protein: 6-157
Range on HMM: 22-156/169.0
KKRVNKAKNRYANIVTYDHSRVVLEKLSNDPHSDYINAsylrdydgspkayiatqgnicinagdfwRMMWQERRCVIVMLTGLieghkKKCHQYWPDSTS
. .|..||| | .. | || |... .| |||||| ||.|. |||.| . ..||.
eltcnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlGdt.....ddknnfwpeked
KYCNLRVTL------------RKTEVFADYIIRTFVMSQVGQTEERYVYQ----YHFTVWPDKGVPQY
| | | . . . | .| | . .. | . .|...||..||||
yqlhpavilGewytdslyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqs
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 22-120 | 3.5e-09 | 31.0 | In-house | 5-92 (130) | alignment | ||
Range on Protein: 22-120
Range on HMM: 5-92/130.0
YDHSRVVleklsndpHSDYINASYLRdYDGSPKAYIATQGNICINAGDFWRMMWqERRCVIVMLTGLIEGHkkkcHQYWPDSTSK-YCNLRVTLR--KTE
.. ||. .|||||.. | . |. || .. .. |||.|| || .... | .| .||||| . . .... . .
fevsrlq........gntyinasfvG.llgrtaeylltqhpladtsmdfwkmml.eryvnvlvvlgsveee....deywpdsePlewyeediivtltdrd
VF
|
ef
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 7-61 | 1.6e-08 | 28.6 | In-house | 45-95 (95) | alignment | ||
Range on Protein: 7-61
Range on HMM: 45-95/95.0
KRVNKAKNRYANIVTYDHSRVVLEklsNDPHSDYINASYLRDYDgSPKAYIATQG
| |||. ||. || .|||| |||||| .. | ..|||.||
seanipknrflnifpydatrvvlt...tkrdsdyinacfvdgya.rkncyiaaqg
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 10-83 | 2.6e-08 | 27.8 | In-house | 37-114 (347) | alignment | ||
Range on Protein: 10-83
Range on HMM: 37-114/347.0
NKAKNRYANIVTYDHSRVVLE-----KLSNDPHSDYINASYLRdYDGSPKAYIATQGNICINAGDFWRMMWQERRCVIV
. .||| . | .|||| . |. |||||... .| . | || || . |||.|. . .|
slsknrskdvklidatrvvlspeksknsraddvetyinashik.fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
|
|||||||||
subfamily_eak_pd | Subfamily eak | 176-241 | 4.1e-08 | 27.0 | In-house | 236-303 (332) | alignment | ||
Range on Protein: 176-241
Range on HMM: 236-303/332.0
ARPWVIHCSAGVGRTGAFLVIDAMLR--QAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFIHLAVLE
. .| .. | |.|.|.||| ..| ..||. . . ... ... | | | .. |. ||. .||.
sfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivld
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 138-235 | 5.1e-08 | 27.6 | In-house | 80-168 (182) | alignment | ||
Range on Protein: 138-235
Range on HMM: 80-168/182.0
ERYVYQYHFTvWPDKGVPQYaTAVLGLRrKITKDSLPGArPWVIHCSAGVGRTGafLVIDAMLRQAKKQKTVdifNYVKAIREDRPHMVQTSEQYVFI
|. .| | |. |.| ||. . .| . |. . .| .|| || |||| ..| ..| ||. .. . .| .|. ||. .|| || ..
eqgiyvynfg.wkDygvasl.eriLdiv.kvvafalqeg.kvavhChaGlGrtG..vliacylvyakrltae...kaiklvrskrpksiqtreqvelv
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 9-94 | 1e-07 | 25.8 | In-house | 33-115 (332) | alignment | ||
Range on Protein: 9-94
Range on HMM: 33-115/332.0
VNKAKNRYANIVTYDHSRVVLEklSNDPHSDYINASYLRDYDGsPKAYIATQGNICINAG-DFWRMMwQERRCVIVMLTGLIEGHKK
| || . .||||| | .| . |. |||.. | ||| .| . . ||||. ||. .... | |. ..|
nnmdmnriphlycfdhsrvela..pqdgkddfynaswvdgysk.ksayifaqapfndhteyvfwrmv.serkpsmilvfgdidekqk
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 96-235 | 2.6e-07 | 24.5 | In-house | 175-330 (347) | alignment | ||
Range on Protein: 96-235
Range on HMM: 175-330/347.0
CHQ--YWPDSTSKYCNLRVTLRKTE-VFADYIIRTFV------MSQVGQTEERYVYQYHFTVWPDKGVPQYATAVLGLRRKITKDSLPG-------ARPW
|. ..| .| .| ||. | .| | | .... . | .| . | | || | |. || | | |.| . |
lhrssffpletdhylnlkgwlintravevdqrnknwmnkytvevvaegcseatfakvyncttwpwkkypddekkvlalvrapvkesstslianleklapv
VIHCSAGVGRTGAFLVIDAMLRQAKKQKTVDIFNYVKAIREDRPHMVQTSEQYVFI
|. | |. |. . .. .. | . || | . | .|..| . | | .
vvmcdlgldrsatvvltsiiieqvldgktpdcddlfkkmrdqragvftmsifytya
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 177-240 | 3.5e-07 | 23.9 | In-house | 266-341 (349) | alignment | ||
Range on Protein: 177-240
Range on HMM: 266-341/349.0
RPWVIHCSAGVGRTGAFLVIDAMLR--QAK---------KQKTVD-IFNYVKAIREDRPHMVQTSEQYVFIHLAVL
. ..||||| |||| . .| .| . .... | |. | .| | ||| |...|. |.|
stllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealL
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 8-47 | 1.1e-06 | 22.5 | In-house | 37-75 (244) | alignment | ||
Range on Protein: 8-47
Range on HMM: 37-75/244.0
RVNKAKNRYANIVTYDHSRVVLEKlSNDPHSDYINASYLR
.| .|||| ||. .|..||.| |. ||||||.|..
sanatknryinilpfdetrvilss.skkegsdyinanyiq
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 141-233 | 1.6e-06 | 23.4 | In-house | 79-167 (194) | alignment | ||
Range on Protein: 141-233
Range on HMM: 79-167/194.0
VYQYHFTVWPDKG-VPQYATAVLGLRRKITKDSLPGARPWVIHCSAGVGRTGAFLVIDAMLRqaKKQKTVDIFNYVKAIRedrPHMVQTSEQYV
..|. .||.| ||.... |. .. . ..|| ||.|||| ... . | . . . .... .| |..... ...
gieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyr..lgmsaeeAialfrekR...pgaipnqdyle
|