Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRD_pd | Subfamily PTPRD | 112-626 | 1e-247 | 818.3 | In-house | 2-514 (564) | alignment | ||
Range on Protein: 112-626
Range on HMM: 2-514/564.0
SKPIPIALFPEYVAKMH--GGIRLETEYKKFNNGQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQG
|||||.| ..|.|||.. .....|.||||...||||.| ||.||| ||.|||||||||||||||||..|.|||. ||||||||.||. .....||.||
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpa..NkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqg
PLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATA
||....| ||||||||||..|||||.|. .|.|||||||.| |||||..||||...| .| || .||.|.|.|.| || ||||||| |||.|||..||.
PlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesats
VLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQ
.|...|||||||..||||..|||| ||.|||..||||||||..|...||||..|..|.||.|..||||.|||.|||.|.||||.|||||..||...|..|
lLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlq
KLASVNGKFPMTGYALEFQRLNsvTSREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVED
|||.|. .. |||..||||||. |..||..||..|..||.|..|||||.|.||.||||.|....|.||||||||..|.|.|...||||||.|| .||||
kLaeveedtemtgleleFqrLa..takeieleefavatkpknkkknrfsnilalescrvvlsairakeesdyinasyleayrekrafiatqaplkntved
FWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT
|||||.......||||..|..... |||||..|..|||||.|.|.||.|..|.|....| ||..|.|...|..||.|...||.. .|..||||||..|..
fwrmvweeevkiivmltkleekleeesseyysdleatkyGeitikvlkkkeksdilfrkkkvevkekseavyllhtvqavdkklltvidsvldllkavrk
SQQQCGNVPVLVQCRYNK
..... .|.| .....
vleravvvrvsegvtvtg
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 109-399 | 8.3e-130 | 427.4 | In-house | 3-298 (298) | alignment | ||
Range on Protein: 109-399
Range on HMM: 3-298/298.0
DDLSKPIPIALFPEYVAKMH--GGIRLETEYKKFNNGQQ----FPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPr
....... .|......|... . .....|....|.... . . .||||. ||.|||||.|.|.|.||||||....||. |||||||.|.|.|..
teieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpe..nkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn.
SFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD-KTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKG
.|||.|.||....|.|||||.|.....|||||||. |.|||.|||||| ..|||| .||.|...|.|| ........||.|....| |||.|||.|||||
afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkg
VPQYATAVLAFRRKVRAlNPRDAG--PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
||..||.||...||||| ....|| ||||.|| ||.|.|..|.||..||..||...||........||.||..|||.|||.||..||||||...|.||.
vpenatsvldllrkvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndeie
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 151-400 | 5.9e-118 | 387.6 | In-house | 4-245 (250) | alignment | ||
Range on Protein: 151-400
Range on HMM: 4-245/250.0
ARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTkCHKYWP-
|.||. ||.|||||.|.|.|.||||||...||.. |||||||.||||.. ..|||.||||....|.|||||.|..|..|||||||. .|| .|.|||
akkpq..nkeknryadiialdssrvvLekekgdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR-DAGPVIVHCSVGVERTGAYIVIDAML
.|.|.||.|||.|...|.|| |. ...|||.|....|||||.||.||||||||..|||||....||.| ... ...||||.|| || |.||.|.|||.|
ekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavl
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCgnteiqS
|..||...||........||.|||.|...|||.|.....|.||.. .
erlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds......v
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 117-429 | 2.2e-103 | 340.6 | In-house | 4-318 (318) | alignment | ||
Range on Protein: 117-429
Range on HMM: 4-318/318.0
IALFPEYVAKM--HGGIRLETEYKKF-NNGQQFPWGAARKPANKnkNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPP
. . . |... .| . |..||... . ... . . .|.|| .|||||||.||||.|| |. ..|.|. |||||..| || ...||.|.|||
vedleshvrrlresGelllseeyerlsrseetvtslkslepvnk..aknryanilaydhtrvkLqmlegeegsDyinanyidGyr.rkkayiaaqaPlpe
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAF
..| ||||||||||. |||||... |.|.|.|||.| ...|| ..|.|... .. | .| ..... . ||.|||.|.| |||.|||. .. .|..
tieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldl
RRKVRALN-PRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLA
|.|.. . . .|||..|||| || ||| .|..|..||..|. .||. .. .|..|. ||||..|| ||. ..||||..|.||..... .. ...|
vrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelr
SVNGKFPMTGYALEFQRL
.. . .| .|||||
eqdpesgttemdaefqrl
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 394-622 | 1e-102 | 338.4 | In-house | 1-230 (298) | alignment | ||
Range on Protein: 394-622
Range on HMM: 1-230/298.0
GNTEIQSEKYNQAMQKLASVNGKFPMTGYALEFQRLNSVTSrEIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRN
|||||..|....|.||||.|. |. .|||||||||||||.| ||. |||.|..||.| .|||..|||||.|.||.|.||.||||||||||.||||..|||
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvss.eieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKK--KTHEVRHLHHVSWTDKC
||||||.|| |||||||||||..||||||||.||... . ..||||.|...||.| .|.|||....|.|..| ||..|| |..|||.||..||.||.
afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkg
IPKVSRSVLDLLDEVQTSQQQCGNVPVLVQC
.|....||||||..|..||||.||.||.|||
vpenatsvldllrkvrasqqqagnkpvivqC
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 115-427 | 1.5e-96 | 318.2 | In-house | 5-319 (319) | alignment | ||
Range on Protein: 115-427
Range on HMM: 5-319/319.0
IPIALFPEYVAKMH--GGIRLETEYKKFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLP
|... . |.. ... | || |.|........ . | |. .||.|||| ||.|||..|||| ..| |. |||||||| ||. . ||| |.||
ievqeLkerlkalastgetllekefkllkeavndtfdsaske..enkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqer.ekfiatqaPle
PAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKGVPQYATAVL
..| |||||||..| .||||.|| | |..||||... |.|| ..||| . | ..|. . | | . .| | .|..| |||..||..||..|
ntiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsll
AFRRKVRALNPR-DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQK
.. ...| . ..||..|||| || |||..||.|||||. |. ..|. .. .| |. |||..|||.||. |.|||...|.|||. .. .. ...
dllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkq
LASVNGKFPMTGYALEFQ
||. . . .|| . |||
laekvadtgetglerefq
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 157-390 | 4.8e-96 | 315.5 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 157-390
Range on HMM: 6-239/239.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETYG
|| ||||||||.|||||||||... | ||||||... |||.|...||.|| . .. ||||.|.. ||||| |. | |||.|||| | |
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskyc
GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT
. |||...|||| | ||..|. .. | | |.|||||||||||||||||| .|||. . | | ..||| || ||||..|||||| |||| .|
nlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqkt
VDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
||| ||. |||. ||||||| ||| ||| |||||
vdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 156-389 | 1.5e-95 | 313.9 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 156-389
Range on HMM: 6-239/239.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETY
|| ||||||||.|||||||||... | ||||||... |||.|...||.|| . .. ||||.|.. ||||| |. | |||.|||| | |
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsky
GGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSR
. |||...|||| | ||..|. .. | | |.|||||||||||||||||| .|||. . | | ..||| || ||||..|||||| |||| .
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqk
TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
|||| ||. |||. ||||||| ||| ||| ||||
tvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 115-405 | 2.1e-95 | 315.1 | In-house | 1-301 (563) | alignment | ||
Range on Protein: 115-405
Range on HMM: 1-301/563.0
IPIALFPEYVAKMHG--GIRLETEYK---KFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGD-EDLDYINASFIHGYDgTPRSFIASQ
.|. | ..||..| |... |.. . . .... ...|| .||.|||| ||||||.||| |. . | ..||||||..|.|| . |||.|
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkp..enkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyq.kskafiatq
GPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSK------EKRSGSRIVRQFHFTVWPDKG
|||. |. ||||.||||.. |||.|||| .. ||. ||| |..|||| ..||| ..||.| | |... . ... . |||.|.| |||.|
gplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhg
VPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSE
||.... || | .| | |...|||..|||| || ||| |||.|..|.| .. .|.. . | || .|...|||.||| |.| |.|||.. ..||...|
vPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellae
KYNQ
. ..
qvee
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 103-395 | 2.1e-91 | 301.7 | In-house | 14-303 (308) | alignment | ||
Range on Protein: 103-395
Range on HMM: 14-303/308.0
ICDNAVDDLSKPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQfPWGAARKPANKNKNKNRYANIVAYDHSRVVLervngDEDLDYINASFIHGYD-GTP
.|. . |..... . ... |... .||.|...... . .. .||.|||| .|..||||||.| ||. ||||||...||. . |
frdtsilvsslklsvldllkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklp
RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD----KTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVW
| ||| ||||| .| |||||||||.. |||||.|| .. ||..|||. ....||..|||| ||...| |..|.. . . ||.|..||.| |
rkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnW
PDKGVPQYATAVLAFRRKVRALNprDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
|| |||......|.| ..|| . . ||..|||| || |||..|..| .||| .| ..||. ... .|..||.||||.||| |.. |.|| | .
pdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 129-409 | 2.8e-91 | 301.4 | In-house | 17-294 (317) | alignment | ||
Range on Protein: 129-409
Range on HMM: 17-294/317.0
GgIRLETEYKKFNNGQQFPWGAARKPANKNknKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQ
.|. |.... . . .. |..|.||. |||| .|. ||||||.| ..||.|.||||||...|.. ... ||| ||||| .| ||||||||...
f.talleefedllslkldtysvaelpenkd..knrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrk.fIatqgPlpntvedFwrmvweqgvt
SIVMLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPV
.|||||.|. |.. ||..||| ..| |||..|||| . |. ||.. |. ... . | ||.|..||.| ||| |||.. . .|.| ..||. .... |||
vivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpv
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQK
.|||| || |||..|... |||| .| ..||. . . .|..||..||| ||| |.. |.|| |....| . .. ...|
lVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllk
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 112-393 | 6.7e-90 | 296.1 | In-house | 4-287 (293) | alignment | ||
Range on Protein: 112-393
Range on HMM: 4-287/293.0
SKPIPIALFPEYVAKMH--GGIRLETEYKKFNN-GQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQ
|||| . | |.|.||. .|. ||..... |.. ||.... |..|||| ||..|||||| |. ...... |||||..|.|| .|| |||.|
skpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelav..nraknrytnilpydhsrvkLaalkdesgsDYinanyipgyn.sprefiatq
GPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK--TETYGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYA
|||| ... |||||||..|. |||||.|| |.||..|||.. . .|| ..||| ..|. . .. ..|||. .| |||.||| ||| |||. .
GPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekeke..erkvrqyhftsWpdhgvPekt
TAVLAFRRKVRALN--PRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTC
...|.| |.|| ...|..|||| || |||..| .| .|.. ... .||| ....|..| ..|||..|| |||..||. |.
ktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 130-408 | 9e-90 | 295.7 | In-house | 21-294 (314) | alignment | ||
Range on Protein: 130-408
Range on HMM: 21-294/314.0
GIRLETEYKKFNNGqqfpWGAARKpaNKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQS
| . ||. . .| | ||.| ..|..|||. .|.|||.|||.| ..|| . |||||..| .| |. ||. ||||. . |||.|...|. |
gygfkeeyeslfeg....wdaakk..denreknrsgdilaydrsrvflitidgdpssdyinaalidsyk.rpaafivtqgPlqetvkdfWrlvydencas
IVMLTNLVGLNKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSK--EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPV
|||||.|| . || ||||..||.|| . |.| ..|. | . . .| ..| . .. |.||||.|. ||| .||..||..|.. |.| . .. .||..
ivmltelvevgrvkClkyWPedtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGri
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQ
.|||| | |||..|.|| .|. ... ..||. | ..|.... ||.|.||| ||. ..||| ||.| | ... .
vvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalyl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 127-391 | 4.6e-89 | 293.9 | In-house | 19-286 (288) | alignment | ||
Range on Protein: 127-391
Range on HMM: 19-286/288.0
MHGGIRLETEYKKFNNGQQFpWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQN
..| .|. |.... . . . .|..|||| .|..||||||.| ..|.|. ||||||.|.||. . . ||| ||||| .| |||||||||
angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweqn
SQSIVMLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSKE----KRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP
.. |||||.|| |...||..||| ....||| .|||| ||...| |..... . . ||.|..||.| ||| |||......|.| |.|| ..
vrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
. |||.|||| || |||..|..| .||| .| ..||. ... .|..||.|||| ||| |.. |.||.|
sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 113-411 | 2.8e-88 | 290.9 | In-house | 4-299 (315) | alignment | ||
Range on Protein: 113-411
Range on HMM: 4-299/315.0
KPIPIALFPEYVAKMHGGIR--LETEYKKFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGP
.|||. . |||. . . .. .|. || .| |.| .||.|||| ||.|||.||| | .. |.. ||.||.|| ||. .| .||.|||
qpipldqlityvaqkkastkngfkqdyesipggqlhpldvakki..enkqknryiniiaydksrvqlpllendphsdyvnanfidGyn.kkrryiaaqgp
LPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFilSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVL
.. . . |||.|.|.. |||||||| .| |. |||||| .|| .|||. . ||. | |. | .. | | |.|.| ||| |||.|.....
nvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdmgvpkytiplm
AFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
. |.|. . ..|...|||| || |||..| .||.|.||. . .|. |.. .|. | .|||. ||| ||..|.||.. ||.| | . | | . |
nlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqrydsl
A
l
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 155-422 | 5.3e-88 | 290.1 | In-house | 55-326 (330) | alignment | ||
Range on Protein: 155-422
Range on HMM: 55-326/330.0
ANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TE
..||.|||. ||. ||.|||.| ..| |. ||||||||.|| .|||.|||. . | ||||.|||.|..|||||.| ...||..||||. .
keenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykek.dkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlv
TYGGVTVTLHQSEVFAGYENCTFILS----KEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLE
||| ..|......| | |.. . .. ||.||||||| ||| ||| . .| . .||..||.. |||..|||| || |||..||.||.||
tyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavle
QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLASVNGKFPMTGY
. | | ||. . . .|. ||.||||.||| ||. ..|| |.||.. .. .||| . .. .|
rvkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekhlqklynkitgtdkigl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 133-396 | 3.2e-86 | 284.5 | In-house | 2-279 (284) | alignment | ||
Range on Protein: 133-396
Range on HMM: 2-279/284.0
LETEYKKFNNGQQFPW-GAARKPANKNKNKNRYANIVAYDHSRVVLERVNGD-EDLDYINASFIHGYD----GTPRSFIASQGPLPPAFEGFWRMVWEQN
|| |... .. . ... . .|..|||| .|..||||||.| ...|| || ||||||...||| ... ||| ||||| .| |||||||||
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
SQSIVMLTNLVGLNKTKCHKYWPDK--TETYGGVTVTLHQSEVFAGYENCTFILSKEK-RSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP--
.. |||||.|| ...||..|||.. . |||..|||| ||. .| |. |.... . ||.|..||.| ||| |||.... .|.| |.|| |..
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSR---TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNT
. ||..|||| || |||..|..| .||| .| . .||. ... .|..||.|||| ||| |.. |.||.| ...|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 157-389 | 6.3e-86 | 282.5 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 157-389
Range on HMM: 2-237/237.0
KNKNKNRYANIVAYDHSRVVLERVNGDedLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD--KTET
.|| ||||.||||||||||||. .. |||||....|.||||...||.|||| .. . ||.|||... ||||| |. |. |||||||. . ..
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGGVTVTLHQSEVFAGYENCTFILSKE-KRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| .||.|.. | |. | ...|||. . . |.. |..||.|||.||||...|.| ||... .| ..|| |.||| || ||| ..|||||| ||
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
|. . ||| ||. .| . ||...|||.|| ||| ..||
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 147-402 | 9.9e-86 | 283.0 | In-house | 28-288 (297) | alignment | ||
Range on Protein: 147-402
Range on HMM: 28-288/297.0
PWGAARKPANKNKNKNRYANIVAYDHSRVVLervnGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHK
.. .|..|||| .|..|||.||.| .||. ||||||.. ||| . . ||| ||||| .| |||||||||...|||||.|| |.. ||..
lgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrk.fIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq
YWP---DKTETYGGVTVTLHQSEV--FAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTG
||| ... |||..|||| || ...| |. ... . . ||.|..||.| ||| |||.... .|.| ..|| .. . |||.|||| || |.|
ywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsg
AYIVIDAMLEQAK---KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEK
..|..| ||.| . | ..||| ... .|..||..||| ||| |.. |.|| | ...| .. |
tfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 107-395 | 1.6e-84 | 279.2 | In-house | 8-293 (297) | alignment | ||
Range on Protein: 107-395
Range on HMM: 8-293/297.0
AVDDLSKPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQfPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNG-DEDLDYINASFIHGYDGTPRSFI
... ..|. . . . |. . .|..|... . . .. |..| .||.|||| .|..||||||.| ..| |.|.||||||.. ||| ..| ||
llesipiplsvldlllllekansktllllefeellslkp.dysiallp..enkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfI
ASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSKekRSGSRIVRQFHFTVWPDKGVPQY
|.||||| .| ||||||||....|||||.|| |.. ||..|||....|||..|||| . |. .|| |. ... . ||.|..|..| ||| |||..
atqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeeggtygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvpps
ATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
.. .| | ..|| . . . |||.|||| || |||..|... |||| .| ..||. . . .|..||..||| .|| |.. |.|| | ...
lellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 128-389 | 3.3e-84 | 277.9 | In-house | 17-275 (278) | alignment | ||
Range on Protein: 128-389
Range on HMM: 17-275/278.0
HGGIRLETEYKKFNNGQQFPWGAARKPANKNknKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNS
. .|. |...... . ... |..|.||. |||| .|..||||||.|. ..||.|.||||||.. ||. ... |||.||||| .| |||||||...
nlktllllefeellsfkldtysiallpenkd..knrykdilpydhsrvklsllggdldsdYinAsyvdgynvprk.fiatqgPlpetvedFwrmvwelgv
QSIVMLTNLVGLNKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPV
..|||||.|| |...||..|||....|||..|||| |....| |. ... . . ||.|...|.. ||| ||| . .| | ..|| .. . |||
ttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpv
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.|||| || |||..|... .|||..| ..||. . . .|..||..||| .|| |.. |.||
lVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 133-392 | 6.7e-84 | 276.3 | In-house | 17-277 (281) | alignment | ||
Range on Protein: 133-392
Range on HMM: 17-277/281.0
LETEYKKFNN-GQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
. .||.|... |.. . |..... |..|||| ||||||..||.... . ... |||||.|. ||.| .. .||.|||.| ... ||.|||||. . ||
fieeyeklaaigvdntataskade..nvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykg.ekeyiatqgPvPaslvafWqmvweqkvsaiv
MLTNLVGLNKTKCHKYWPDKT--ETYGGVTVTLHQSEVFAGYENCTFILsKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKV-RALNPRDAGPVI
|.|. . .| |||.||||.. .|| |||. ...| | | . .| | ... . .| |.|...| |||.|||. ....| ||..| .. ... |..
mvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplv
VHCSVGVERTGAYIVIDAMLEQAK-KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALT
.||| || |||.|| .| ...... . ...|... . .||.| |||| ||.|.. |||.||
ihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 126-391 | 2.7e-83 | 274.9 | In-house | 7-272 (273) | alignment | ||
Range on Protein: 126-391
Range on HMM: 7-272/273.0
KMHGGIRLETEYKKFNNGQQfPWGAARKPANKNKNKNRYANIVAYDHSRVVLervnGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQ
|. | .|. |.... . . .. .||.|||| .|..||||||.| ||.. ||||||.. ||. ... ||| ||||| .| ||||||||
kllgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrk.fiatqgPlpntvedfwrmvweq
NSQSIVMLTNLVGLNKTKCHKYWPDK----TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP
|.. |||||.|| |.. ||..|||.. ..||| .|||| |....| |..|.. . . ||.|..||.| ||| |||.. . .| | ..|| .
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale
R--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
. |||.|||| || |||..|..| .|.| .| ..||. ... .|..||.|||| ||| |.. |.|| |
alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 114-411 | 3.3e-83 | 274.3 | In-house | 3-303 (305) | alignment | ||
Range on Protein: 114-411
Range on HMM: 3-303/305.0
PIPIALFPEYV--AKMHGGIRLETEYKKFNNGqQFPWGAARKpaNKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPL
.| .. . .|. |... ||..||.. . . . .| ..||.|||...|. .|..|. | . ..| ||||||...||.. ..|..||||
iialddlaayikearvysdkgleaqykslyee.eesidvgkk..eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrk.kkyivaqgPl
PPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET---YGGVTVTLHQSEVFAGYENCTFILSK-EKRSGSRIVRQFHFTVWPDKGVPQYAT
. . |||...| ..|||||.|| .| ||..|||... .| ..|.|.... ...| . . .|. .. . || | |...| |||.||||.||
kntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfat
AVLAFRRKVRALNPRDAG-PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQA
..| . ..|. .| | |..|||| || |||..|..| .||..|| .||. ..| ..|..|. ||||..|| |.| |. | .|||.|.| . .. .
sllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrar
MQKLA
..||
vnklk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 442-622 | 8.5e-82 | 269.1 | In-house | 1-182 (250) | alignment | ||
Range on Protein: 442-622
Range on HMM: 1-182/250.0
KSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPeSSEYWPD
|||..||||..|||..|||||.|.||.|.||..|.|||||||.|||....|.||||||.|| .|.|||||||.....||||||.||... ..|||
ksvakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
HGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE--VRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQC
.|.|||.. .|.|||....|.. | |....||..| ||.||.|.| ||..|.| ..||.||..||.||||.|| ||.|||
ekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqC
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 128-391 | 1.1e-80 | 266.9 | In-house | 24-304 (307) | alignment | ||
Range on Protein: 128-391
Range on HMM: 24-304/307.0
HGGIRLETEYKKFNNGQQF-PWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGD-EDLDYINASFI--------HGYDGtPRSFIASQGPLPPAFEG
. .|. |..|... . | .. .||.|||| .|..|||.||.| ..|. || ||||||.. .||| .| ||| ||||| .|
dfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydl.krkfIatqgPlpetved
FWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK--TETYGGVTVTLHQSEVFAGYENCTFILSKE-KRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRR
||||.|||... |||||.|| |.. ||..||||. . ||| .|||| |. .|| |. .. . . ||.|..||.| ||| |||.. .|.| .
FwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfie
KVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT---VDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
.||. . . . |||.|||| || |||..|... ||.| .| | ||... . .|..||..||. ||| |.. |.|| |
evrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 132-410 | 3.4e-80 | 264.4 | In-house | 23-305 (307) | alignment | ||
Range on Protein: 132-410
Range on HMM: 23-305/307.0
RLETEYKKFNNGqQFPWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
|. ||.| .. ... . . |. |||| .|.|.|. ||.|...||.|| ||||||||.||. . ..|||.|.|. . ||||..||... ||
glakeyekLear.eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykek.kkfiaaqdPveatigDfWRmiaeqevtliv
MLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-----SRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG
||.|| |. ||.|||| ... || . |.| ..| | . .. .|| | .. || | |.|.| |.| ||. |...| . ..|| |. . .
mlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrs
PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
|..|||| ||.|.| .. .| .|.| |. .||| . .|..|. .|| |||.|.. |.|. . |.|... .....|...|
PivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledaierl
|
|||||||||
DSPc_SM00195 | 134-391 | 6.6e-80 | 263.6 | In-house | 3-262 (263) | alignment | |||
Range on Protein: 134-391
Range on HMM: 3-262/263.0
ETEYKKFNNGQQFPwGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVML
..|..| .. .. . .|||.|||| ||. |||.|| |.. ...|. |||||..| |. ....|| ||||| .| |||||||.... ||||
keefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivml
TNLVGLNKTKCHKYWPDK---TETYGGVTVTLHQSEVFA-GYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
|. . .|.||..|||.. .||.| ..|.| . | .. |. |.||... .| |.|.... |||.|||. .. ||.. |.|. . . ||..|
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
||| ||.|||....|| .|.. .. .||| . . ..||.||.||||.|||.||. |.||..
hCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 134-391 | 6.6e-80 | 263.6 | In-house | 3-262 (263) | alignment | |||
Range on Protein: 134-391
Range on HMM: 3-262/263.0
ETEYKKFNNGQQFPwGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVML
..|..| .. .. . .|||.|||| ||. |||.|| |.. ...|. |||||..| |. ....|| ||||| .| |||||||.... ||||
keefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivml
TNLVGLNKTKCHKYWPDK---TETYGGVTVTLHQSEVFA-GYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
|. . .|.||..|||.. .||.| ..|.| . | .. |. |.||... .| |.|.... |||.|||. .. ||.. |.|. . . ||..|
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
||| ||.|||....|| .|.. .. .||| . . ..||.||.||||.|||.||. |.||..
hCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 133-390 | 6.9e-80 | 263.2 | In-house | 23-278 (288) | alignment | ||
Range on Protein: 133-390
Range on HMM: 23-278/288.0
LETEYKKFNN-GQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
.. ||.. . ... |.|.. .|..|||| ||..||. || |. .. .. ||||||.|.|.... . .||.||||. . . ||..|.|.... ||
fseeynsLaalektksvtagrla..vnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkk.kkyiatqgPladtvndfWelvyenktstiv
MLTNLVGLNKTKCHKYWPDKTE--TYGGVTVTLHQSEVFAGYENCTFILSkeKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
|||.|| .||||..||||. . || ||||| .|. . . ...| |. . . . |.....|||.|||. .. .|...|.| |. |.||.||
mltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiiv
HCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
||| || ||| .|..||.... ... ..|. . . .||.|. .|||..|| ||....|.
hCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 114-434 | 5.5e-78 | 257.3 | In-house | 1-319 (515) | alignment | ||
Range on Protein: 114-434
Range on HMM: 1-319/515.0
PIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtPRSFIASQGPLPP
|.|.| || .|.| . |.. . . .| |.. | .|||| ||. || .|| || .| . . ||.|||.|...| ...||||||..
plplaqfPafvnknrhttlfseefhdlpgpniypqtvaqeei..nfkknryknilPydsvrvklevindnPhsdyfnasyipsfdn.dkayiasqgPnka
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYATAVL
. . |||.|...| |.|.|.| .| || ||||| .. .| . | | | .| .. . |.. || | ||||| |||||||. ....|
svddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssll
AFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
. ..|.| . . . |.|.||| || ||| .| || .. .||..|.||. |.. ||..||..|||.|||.||. |||| | || | .. . .| |
klikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdl
ASVNGKFPMTGYALEFQRLNSVTS
| . . ||| |.|..
hssgdgrgrskmtkefqtlkslcp
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 113-415 | 2.5e-77 | 254.8 | In-house | 1-301 (315) | alignment | ||
Range on Protein: 113-415
Range on HMM: 1-301/315.0
KPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtPRSFIASQGPLP
.|||.| || .| | . . |.. . . . .. .||.. | .|||| ||. .|..||.|| .. . | ||||||.|...| ...|||||||.
qpipvaqfpafvnknrhtalfseefhdlpdPdiyrqrvaretin..fkknryknilPldsarvkleviddsPdsdyinasyiksvdd.dkayiasqgPlk
PAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKrsGSRIVRQFHFTVWPDKGVPQYATAV
. . |||||.... .|||.|.. .| || .|||| .. .| . |.| . | .. . ... | . || | ||.|| ||||||.. ....
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkse..esrtvtqfqftewPdkGvdkqtssl
LAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQK
| . ..|.| | .. ...|||| || ||| | || ...|.|..|.||. |.. .|..||..|||.|.|.||. |||| | || | .. . .|
lklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqd
LASVNG
| . .
lhtsvd
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 158-389 | 6.2e-77 | 253.5 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 158-389
Range on HMM: 1-235/235.0
NKNKNRYANIVAYDHSRVVLERVNGDEDldYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTET
||.|||| .|..||..|| |. .|..| ||||....||. ....|||.||||. .| ||||||......|||||.|. ...||..||| ....|
nkkknRykdilpydktrvklkgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGGVTVTLH-QSE-VFAGYENCTFILSKEKRS-GSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| ..|.| ... ..| .. |.|.|.. .|.|.|.|.| |||.|||. ....| . |||. . . |||.|||| ||.||| ....|..|||.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.. ..||. ... .||.||.|||. ||| |.. |.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 158-389 | 6.2e-77 | 253.5 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 158-389
Range on HMM: 1-235/235.0
NKNKNRYANIVAYDHSRVVLERVNGDEDldYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTET
||.|||| .|..||..|| |. .|..| ||||....||. ....|||.||||. .| ||||||......|||||.|. ...||..||| ....|
nkkknRykdilpydktrvklkgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGGVTVTLH-QSE-VFAGYENCTFILSKEKRS-GSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| ..|.| ... ..| .. |.|.|.. .|.|.|.|.| |||.|||. ....| . |||. . . |||.|||| ||.||| ....|..|||.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.. ..||. ... .||.||.|||. ||| |.. |.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 133-410 | 2.6e-76 | 252.0 | In-house | 36-310 (319) | alignment | ||
Range on Protein: 133-410
Range on HMM: 36-310/319.0
LETEYKKFNNGQqfPWGAARKPA--NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSI
|| |... . . .| .. | ..||.|||. ||.|.|...| |||..| | |||||||. || . .||.||||. . . ||||.||.|. .|
levefrracklg..vnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyq.rkdkyiaaqGPldntladfWrmiweyncsti
VMLTnlvglnKTKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSK-EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG--P
|.|| | || .||| |. .... | .. | | | . ||. | . | ..|||| |||.|||.|.. .. . .||| |. . . .
vllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhran
VIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
..|||| || |||.|||.|..|.. |. . ||. |.. .|. |...|| || ||.||.|| |.... . ...|
ivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleel
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 157-391 | 4.1e-76 | 251.1 | In-house | 10-246 (249) | alignment | ||
Range on Protein: 157-391
Range on HMM: 10-246/249.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP-DKTETY
.||.|||| .|..||||||.|. ..| .. ||||||.|.||. ..| ||| ||||| ..| ||||.||.....|||||.|| |.. ||..||| ... .|
enkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsley
GGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKK
|..|||| . ||...| |. |.. . . || |.....| ||| |||.. .|.| ..|| . . . |||.|||| || |||..|... |||| .|
gdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlek
SRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
..||. ... .|..||..||. ||| |.. |.|| |
elgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 157-390 | 2.9e-75 | 248.1 | In-house | 8-242 (245) | alignment | ||
Range on Protein: 157-390
Range on HMM: 8-242/245.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP-DKTETY
.||.|||| .|..|||.||.| ..||.|.||||||...||. ||. |||.||||| .| ||||.||.....|||||... |.. ||..||| . . ||
enkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgeslty
GGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP-RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKS
|..|||| |....| |. ..... . || |...|.. ||| ||| . .| | . || . |||.|||| || |||..|... ||||..|
gdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqleke
RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
..|.. . . .|..||..||| .|| |.. |.||
lgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 156-410 | 5e-75 | 247.6 | In-house | 23-274 (284) | alignment | ||
Range on Protein: 156-410
Range on HMM: 23-274/284.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTnlvglnKTKCHKYWPDKT-ET
..||.|||. .|.|.|...| |||. | | |||||||| || . .||.||||. . . ||||.||.|. .||.|| | || .||| |. ..
dqnkdknrighilafdknvvklerliGeefsdyinasfitGyq.rkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik
YGGVTVTLHQSEVFAGYENCTFILSK-EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG--PVIVHCSVGVERTGAYIVIDAMLEQA
.. | .. | . | . ||. | . | .||||| |||.|||.|.. .... .||| |. . . ...|||| || |||.|||.|..|..
eerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrm
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
|. . ||. |.. .|. |...|| || ||.||.|| |.... . ...|
keekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleel
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 113-403 | 1.9e-74 | 245.5 | In-house | 8-296 (297) | alignment | ||
Range on Protein: 113-403
Range on HMM: 8-296/297.0
KPIPIALFPEYVAKMHggiRLETEYKKFNNGQQFPWGAARKPANK-NKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtprSFIASQGPL
.|||.. |. .| | . . . ....|. . .. . .| | .|.||.||. || ||| |. || | | ||.||||..|. .|..| |
rpiplsdfatlvqknr...htdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh...rlittqmPm
PPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQ--YATA
. . . ||.||.... . ||||... .| || .||.||. |.| |.|.|. . |. . .. ..|.| |.|.|..|. |||| |.. |..
katvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsass
VLAFRRKVRALNPRDAG-PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKY
.| . || | |..|||. || ||| .. || .. .||. .||| ... .|..||..|||||||.|.. |||||| . .|.||.. .
llklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqasyf
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 157-394 | 3.4e-74 | 245.0 | In-house | 32-275 (278) | alignment | ||
Range on Protein: 157-394
Range on HMM: 32-275/278.0
KNKNKNRYANIVAYDHSRVVlervngdedlDYINASFIHGYdgtPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT-ETY
.|..|||| .|..||||||. ||||||.|.|| |. ||| ||||| .. ||||.||.....|||||.|| |.. ||..|||.. .||
gnldknRykdilpydhsrVk..........dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggslty
GGVTVTLHQSEVFAGYENCTFILSKE----KRSGSRIVRQFHFTVWPDKGVPQYA--TAVLAFRRKVRALNPR-------------DAGPVIVHCSVGVE
|..|||| . ||. | .|... . || |...|.. ||| ||| . . .| . . .|. . . . |||.|||| ||
gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvg
RTGAYIVIDAMLEQAkkSRTVDIRNYLIAIRKHRPH-MVQTKEQYSFIHSAVLEALTCG
|||...... |||. ..||. ... .|..||. .||..||| |.. ..|| | .|
RtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 151-390 | 4.5e-72 | 237.6 | In-house | 49-296 (306) | alignment | ||
Range on Protein: 151-390
Range on HMM: 49-296/306.0
ARKPanKNKNKNRYANIVAYDHSRVVLErVNGDEDLDYINASFIH-GYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP
..|| .||.|||| ||. .||.||.|. .. . |||||..|. |. .|.||.|| |. . ||||||..||. |||.|. | .| || .|||
gakp..enkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWP
DKT--ETYGGVTVTLHQSEVFAGYENCTFILS-KEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRA----LNPRDAGPVIVHCSVGVERTGAYI
|.. |.|| ..|| ... | |. .. .| |.| . .| |.|.||..|||.|||. |||.| ..|.. |. ..|||..|||| |. |||..|
deeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfi
VIDAMLEQAKKS---RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
|||..|.. .|. .||.. .|..| .|||..|| |.. |. .
viDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikky
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 133-392 | 5.6e-72 | 237.1 | In-house | 17-278 (290) | alignment | ||
Range on Protein: 133-392
Range on HMM: 17-278/290.0
LETEYKKFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVM
| .. .|. . .... |..|. .|..|||| .|. ||.|||.|.. ...|. |||||.||.| .|. ..||.||||| . . ||||.||.| . .||
lkklsekykaekvysteageke..envkknrykDilPydksrvelskieeeegsdYinanfikgvegk.leyiaaqgPLpktlddfWrmiweknveivvm
LTNLVGLNKTKCHKYWPDKT---ETYGGVTVTLHQSEVFAGyENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
. ..| |.|.||..|||... ..| ..|||.. . . . | |... ||.|.|||.| |||.|||. |. .|.. ..|| |. ... |..|
aCrevelgkkkCerYWpeegeeelefgefevtleeekavdd.dflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvv
HCSVGVERTGAYIVIDAMLEQ---AKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALT
||| || |||. |.|| . |. | . ..|. . .. .||.|. .|||||||.... ||.| ..
hCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 157-389 | 3.2e-69 | 228.5 | In-house | 9-240 (243) | alignment | ||
Range on Protein: 157-389
Range on HMM: 9-240/243.0
KNKNKNRYANIVAYDHSRVVLervngdEDLDYINASFIHGYDgtpRsFIASQGPLPPAFEG----FWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT
|..|||| .|..||||||.| |. |||||..| ... | .||.||||| .| ||||.||.....|||||.|| |.. ||..|||...
enlsknrysdilpydhsrvkl......egsdyinanliyvtp...r.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgev
eTYGGVTVTLHQSEVFAGYENCTFILSKEK-RSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAL--------NPRDAGPVIVHCSVGVERTGAYIV
|||..|||| ..|....| |. |. . .| |...|.. ||| |||. . .|.| ..||. . . |||.|||| || |||..|.
.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtlia
IDAMLEQAkksrTVDIRNYLIAIRKHRPH-MVQTKEQYSFIHSAVLE
.. ||.. .||. ... .|..||. .||| .|| |.. |.||
aylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 113-416 | 8.1e-68 | 223.6 | In-house | 2-262 (392) | alignment | ||
Range on Protein: 113-416
Range on HMM: 2-262/392.0
KPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLP
.|||.| || .| | . . |.. . . . .| .|.|. | ..|||| ||. || .||.|| .. | ||.|||.|...| ...|||||| .
qpipvaqfpafveknrhsalffeefhdlpgpdiypqtvaqkein..lkknryknilpydsarvkleviddipdsdylnasyipsfdne.kayiasqgpna
PAFEGFWRMVWEQNSQSIVMLTNLVGLNktkchkywpdktetyggvtvtlhqsevfagyenctfilskeKRSGSRIVRQFHFTVWPDKGVPQYATAVLAF
... |||||...| .|.|.|.| . | | | ||||| ||||.||......| |
aslddfwrmvfqenvttiamvtklkegd.........................................kgddartvaqfhftewPdkdvpkhtssllkf
RRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLA-
..|.| . . |.|.||| || ||| | ||... .|||.| ||. |.. ||..||.||||||||.||. |||| | || | .. . .|.|
ikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlst
SVNGK
|..|.
ssdGd
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 156-389 | 4.2e-67 | 221.1 | In-house | 26-266 (274) | alignment | ||
Range on Protein: 156-389
Range on HMM: 26-266/274.0
NKNKNKNRYANIVAYDHSRVVLERVNGDE-DLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET
....|||| .|. ..|||.||. .... |..|||| .|.|||.. . ..| ||||| . . ||||......| |||||.| |..||..|.||....
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
-----YGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR---DAGPVIVHCSVGVERTGAYIVIDA
||.| .. .. .|. ...|.. .| .| | . .| |||. .|. |...| . ..|. . . ..||.|||| |. |||..| |.
eiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
MLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
. | ... .||. . .| .| ||||.||| .|| |. .
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 133-389 | 4.3e-67 | 221.2 | In-house | 18-288 (297) | alignment | ||
Range on Protein: 133-389
Range on HMM: 18-288/297.0
LETEYKKFNNGQqfPWGAA-RKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
| ||.. | . . | . . . | .||||.... ||..||||..|..|| |||||.|. || ...||| ||||. ... ||||||||. ||
lskeyaeirnep..veGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGyk.qkkafiatqGplkktvsdfWrmvWeqevlviv
MLTNLVGLNKTKCHKYWP---DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRA--------LN
| | .| . || .||| .... .| ..|. . |. |. .. ... | . || | | |. ||| |||. |...| ...||| |
mttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelg
PRDA-----GPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.... |..|||| |. |||..| .| |.. .. |||... . .|. | ...|| ||| | . ||||
dewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 149-420 | 7.8e-67 | 220.7 | In-house | 41-314 (325) | alignment | ||
Range on Protein: 149-420
Range on HMM: 41-314/325.0
GAARKPANKnkNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMV--WEqnsQSIVMLTNLVGLNKTKCHK
.| ||.|| .|||. |.||.|.|||||| . | . ||||||... . . |.|.| ||. . . .||.| |. |.|...| . |.| .| .
kvamkpenk..aknrfknvvaldksrvvletkkddpssdyinasylrddkkk.dvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcav
YWPDK---TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAL------NPRDAGPVIVHCSVGVER
|||.. . |.||. | | | .. | . . . |. .| |.||.. |.| ||... ...... . | |. | . ..|..|||| || |
ywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGr
TGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQamqKLASVNGKFPMT
||..| . ..|.. . ||| ... .||.|| ||.| .||..|. |. ||. .|||.. .. ||.|.. . |.|
tGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfea...klsslqernplt
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 115-395 | 1e-66 | 219.8 | In-house | 2-287 (290) | alignment | ||
Range on Protein: 115-395
Range on HMM: 2-287/290.0
IPIALFPEYVAKM--HGGIRLETEYKKFNNGQQfPWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDED--LDYINASFIHGYDGTpRSFIASQGP
||. | |.||. .| . ....|....|.. . . .. ...||..||.|||| || |..| ...|..| .||||..|.|| ...|| |||
ipvdkfgefvanghakgnegfrnqfkmldsges.ehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykek.kqyiatqgp
LPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKR-SGSRIVRQFHFTVWPDKG-VPQYAT
.. ||...|.... |||||| . .|.||..||||. |..|| ....|.. |.. .| . .. . ... ...| |...| |...| |....|
vsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqt
AVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
.|.... .. | ....|||| .| |.. ..... ....|. .|. . | | .| .|||..|| .|.. ||..|.. .
illvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfe
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 115-398 | 3.4e-66 | 218.2 | In-house | 2-285 (287) | alignment | ||
Range on Protein: 115-398
Range on HMM: 2-285/287.0
IPIALFPEYVAKMH--GGIRLETEYKKFNNGQQFPWGAARKPANKNKNKNRYANIVAYDHSRVVLErvngDEDLDYINASFIHGYDGTpRSFIASQGPLP
||. | |.||| | | .. .. ... .| . . |..||.|||...|. .| ||.|. .|. |||||.|| || . ||....|.
ipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykek.kafiiaesPmf
PAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKG-VPQYATAV
. ||......| . ||||... .. .|..|||... ..| ...| . || ||| . .. . .....| . |.|...| |...| |....| .
ntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtil
LAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEI
| . ..... | ....|||| .| |.. .. .. ....|. ..|. . | | .|..||| ||| || .||| |....|
lvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 141-399 | 2e-64 | 212.1 | In-house | 17-281 (290) | alignment | ||
Range on Protein: 141-399
Range on HMM: 17-281/290.0
NNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGdedlDYINASFIHgYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLN
.. ..|| .|..|.| .|.||| .. |||||..||| . ||||||... . ||.| .||||| . . ||.|||||.|...||| ..| .
keasdfptreaklpen..rnlnryrdvspydhsrikleradn....dyinaslve.leeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvveke
KTKCHKYWPDKTE----TYG--GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAL--NPRDAGPVIVHCS
..||..||| . | .. ..|.| . |. | .. | . | .| . .||.| ||| |||. .| | | ||| .| ||...|||
qikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcs
VGVERTGAYIVIDAMLEQAKKSR---TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTC--GNTEIQ
|. |.|.....|..| . .|. .|||.. |...||.| ..||..| | . |.|| . |.. .|
aGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdssvq
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 148-390 | 1.4e-63 | 209.5 | In-house | 33-274 (280) | alignment | ||
Range on Protein: 148-390
Range on HMM: 33-274/280.0
WGAARKPANKnkNKNRYANIVAYDHSRVVLERVNGdedlDYINASFIHG-YDG--TPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKC
|||||.| .|||| .|..||. || |. . |||||... .. . .||.||||. . . ||.|||||.|. |||||.|| ..||
isaarkpenl..sknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkC
HKYWPDKTE--TYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYI
|.|||.... .||. .|...... | ..|.... . .| . |. .. |||.|||. .. .| | ..||.| . ||.|||| |..||| .|
hqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvli
VIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
... | ... | . . . .| | .|||..|| |. |.|..
lletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 156-395 | 6.9e-63 | 207.0 | In-house | 40-294 (296) | alignment | ||
Range on Protein: 156-395
Range on HMM: 40-294/296.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDK-TET
..|..|||. ..| ||. |||||...|.|. |||||... .. .. .| ..| . . |||.|........|.||. .| ....||| | |
kenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsfl.kkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeq
YGGVTVTLHQSEVFAGYENCTFILSKE----------KRSGSRIVRQFHFTVWPD-KGVPQYATAVLAFRRKVRALNPRD-----AGPVIVHCSVGVERT
|| . | . ... .| . || | |. |||..|..|.|. . || ..|.. .||.|| . . |||.|..| |. |.
ygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRs
GAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
|.|. ||| ||...| ||. ... .|..||..|...|.| .| .|||. |.
GvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 154-392 | 8.2e-63 | 207.2 | In-house | 33-270 (273) | alignment | ||
Range on Protein: 154-392
Range on HMM: 33-270/273.0
PANKNKNKNRYANIVAYDHSRVVLERVNGdedldYINASFIHGYDGTP-RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT
..||.|||| |.. ||..|| |. | |||||.|. | ..||.||||| . . ||.|||||... |.|.|. . .| |||.|||...
kkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesk
E----TYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPrDAGPVIVHCSVGVERTGAYIVIDAML
. .. ..|.| . . |. .. ... . . || | ...|. ||| |||. |. .| | ..|| |. ||||..|||| |. |.|..|.||..|
nkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidvvl
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALT
. .. . .|... . .|. | .||||.|| |.. |.||.|.
glierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 132-390 | 9e-62 | 203.4 | In-house | 30-291 (297) | alignment | ||
Range on Protein: 132-390
Range on HMM: 30-291/297.0
RLETEYKKFNNGQQFPWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
||| |.. . . .. | .. |.|| .|||......|||||| |.. . .|. ||||||.| | ..||.||||. ||.||||| . ||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvviv
MLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFA-GYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
.||.| . ..|..||||. .|.|. | | ... | .| | . | .| | |||| ||..||| | ..| ||||| . |..|
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivv
HCSVGVERTGAYIVIDAMLEQAKK-SRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
||| |. |||.||.|| .|.. .| . .|| | .| ||..|.||.|. |. .|| |
hcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 156-389 | 1.2e-61 | 203.1 | In-house | 18-262 (270) | alignment | ||
Range on Protein: 156-389
Range on HMM: 18-262/270.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET-
..|. ||||.|. ..||.||... |. |||| ...|.|| ....||..|||| . . ||||.||.....|||.|.|. ...|| .||| ....
argkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
----YGGVTVTLHQSEVFAGYENCTFILSkEKRSGSRIVrQFHFTVWPDKGVPQYAT------AVLAFRRKVRALNPRD--AGPVIVHCSVGVERTGAYI
.| ..|. ..| || | || . |.| |... |||.|||. . .|. |.||. . . |.|..|||| ||.||| |
vkledgkikvlalseekeegyiltrlrle.ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtli
VIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
..| ... .... ||. . . ..||.|. .||. ||| |.. ||.|
alDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 157-405 | 2.7e-60 | 199.1 | In-house | 47-293 (439) | alignment | ||
Range on Protein: 157-405
Range on HMM: 47-293/439.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtkchkYWPDKTETY-
.. |||| ...|.||.||.|. . | |||| .|.|| ... .||.||| . . |||.|.|... |||||||| | ||| ..|..
ydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyy.ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcy
GGVTVTLHQSEVFAGYENCTFILSKEKR--SGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP-RDAGPVIVHCSVGVERTGAYIVIDAMLEQAK
| ..| . . | | . .|. | | |||.. |||| || |. || | | . . | .. |||.|||| || |||. | .| ||| |
gdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlk
KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQ
|||. . .||.| .|||. || ||. |||| . |.. .. .....
lenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkk
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 132-390 | 6.4e-57 | 187.6 | In-house | 16-279 (288) | alignment | ||
Range on Protein: 132-390
Range on HMM: 16-279/288.0
RLETEYKKFNNGQQFP-WGAARKPANKNKNKNRYANIVAYDHSRVVLErvnGDEDlDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSI
|....|.... |. . . |... .|||. .|. |||.||.|. | .| |||||||... . .|||.|.||... ||.||.|| |. |
aldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...gskD.DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssvi
VMLTNLVGLNKTKCHKYWP---DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRA----LNPRD
|||.. |.|.|...||| ..|...| ..|||.. . . . ...|. .. . . |. ..| ||. |||. .|.| .|.. . .
VmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrks
AGPVIVHCSVGVERTGAYIVID-AMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
|..|||| ||.|||.. .. |. | |. .|| . . .|. | .|||.|||. | .|||||
ktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 394-623 | 4.2e-54 | 179.3 | In-house | 1-227 (288) | alignment | ||
Range on Protein: 394-623
Range on HMM: 1-227/288.0
GNTEIQSEKYNQAMQKLAsvngKFPMTGYALEFQRLNSVTSReipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRN
|.|||. |.. ....|| . .||.. ||..| |.. . |.. .|.||.|||.|||......|| |. .. .|.|||||| ... .. .
gdteisveellklvlkll....angltglleefeellsllpd....ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkr
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVT------RKKKTHEVRHLHHVSW
.|||||.|| .||||||||| .... .||||..|.. . |||..| ..||.| . || ....|... . .|| ......|.|.|. .|
kfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnw
TDKCIPKVSRSVLDLLDEVQTSQQqCGNVPVLVQCR
| ..| ...||.| .|..... |. ||.| |.
pdhgvpdspellldflrlvrkala.sgggpvvVHCs
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 133-397 | 5.4e-54 | 177.9 | In-house | 17-299 (301) | alignment | ||
Range on Protein: 133-397
Range on HMM: 17-299/301.0
LETEYKKFNNGQQFPWGAARkpANKNKNKNRYANIVAYDHSRVVLERVNG--DEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSI
.| .||. ..|.. . ..||. ||. ||. ||. |..|. . .|||||.|.|| . . |||.|||. |||..|.. .||
feeqykelkegedksctvgl..seenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysek.kkfiaaqgpmkktlvdfWrliwqekpvsi
VMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAG-----------------YENCTFILSKEKrsGSRIVRQFHFTVWPDKGV-PQYATAV
||.||| |.||..|||. ..|..| .||||... |. | . .| ...| |. | |.. | ||. || ....| .
vmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvL
LAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTE
. . . . . |||.|||| .| |.| |. .. |||.| ||. . |.|. .| .|.| |||..|. .. . |.. .|.
qviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 391-623 | 2.7e-53 | 176.7 | In-house | 12-240 (308) | alignment | ||
Range on Protein: 391-623
Range on HMM: 12-240/308.0
LTCGNTEIQSEKYNQAMQKLAS-VNGKFPMTGYALEFQRLNSVTSreipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLhkehaDEESDYINAVFLHAH
|....|.|. ..... ...|. ..... .... ||..|.||. ..| ||...|.| .|||..||... ..|| | ||.|||||| . . .
llfrdtsilvsslklsvldllkllekaldlglleeefeellsvkp....lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgy
--RGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH---GATKYGHIGISVLSKQKKGDVICVKPKVTR--KKKTHEVRHL
. ...|||||.|| .||||||||| .... .||||..|.. . .|||. | ..||.. . .|| ....|... . ..| ......|.|.
ssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthf
HHVSWTDKCIPKVSRSVLDLLDEVQTSQqqcGNVPVLVQCR
|. .| | ..| ...||.|..|..|. .. |..| |.
hytnWpdhgvPpspeilldflelvrksl...pggpivVHCs
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 151-399 | 1.3e-51 | 170.2 | In-house | 26-274 (283) | alignment | ||
Range on Protein: 151-399
Range on HMM: 26-274/283.0
ARKPANKNKNKNRYANIVAYDHSRVVLERVNGdedlDYINASFIH--GYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYW
. |..||.|||. .||..| || |. . |||||.|| . . .|..|.|| . ||.||.... .|||||.| .. || .||
diasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyW
PDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDA
| . .| || ||||.. . ..| .. . . .. . . | . | ... | . . . ||..|||| |. ||...| . |
PkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasa
MLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
...|. . ||. . . .|..|. .|||..|| ..| .||| ||.|.|
svkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqia
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 155-391 | 3.5e-50 | 165.7 | In-house | 46-296 (300) | alignment | ||
Range on Protein: 155-391
Range on HMM: 46-296/300.0
ANKNKNKNRYANIVAYDHSRVVLERVNgDEDLDYINASFIHGY-DGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK--
..|..|||. ... |...|| | . ... .||||| |. |. ||.|..||||. . . ||.|||||. | |||||. |.|..||.|..
lpenaeknrfkdvlPyednrvelsptk.enstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkles
---TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR---------DAGPVIVHCSVGVERTG
| ..| || . || . .. | . | | . .| |||.|||. . | . ..|... . ||.|||| || |||
kkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtG
AYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
|. | ... .. ...||.. | .|. | ..||| || |....... |
vlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 150-388 | 1.1e-49 | 163.7 | In-house | 32-274 (287) | alignment | ||
Range on Protein: 150-388
Range on HMM: 32-274/287.0
AARKPANknKNKNRYANIVAYDHSRVVLErVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP
|| . |. .|||||... .|..||.| .|. ||||| .. .| .|||.|||.. . |||.|.|..| |....| | . ||.||||
aaeelaa..vkknryadvlPiddtrvlls.aegelGsdyinanyvasytdd.eafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywP
DKTE--TYGGVTVTL-HQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKV-----RALNPRDAGPVIVHCSVGVERTGAY
.. || .|.| .. | .. | . . .|.|.|... ||||... | ... | .| | . ..||..||..||. |.| .
erevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGil
IVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVL
. . ..... .. ||. . .| .|..| .||. |. .. |.
latlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 424-623 | 2.8e-49 | 163.4 | In-house | 4-212 (284) | alignment | ||
Range on Protein: 424-623
Range on HMM: 4-212/284.0
LEFQRLNSVTSREIpvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAD-EESDYINAVFLHAH-----RGRNAFIATQHPLLETVEDFWRMVTDYD
||..|.|.| . . ||. .|.||.|||..||......|| |. .. | |.|||||| ... . . ...|||||.|| .||||||||| ...
eefeellsltvkll..lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
IGTIVMLNNLHDQVAPESSEYWPDHG-ATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ-
. .||||..|.. . |||. | .||.. . .||...|.|... . ..|. ......|.|.|. || | ..| ....|..|..|......
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
CGNVPVLVQCR
|. |..| |.
pgggpivVHCs
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 423-622 | 4.3e-49 | 162.3 | In-house | 23-220 (318) | alignment | ||
Range on Protein: 423-622
Range on HMM: 23-220/318.0
ALEFQRLNSVtsREIPVEEKSvgEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIV
|..||. . .| . . || .| | .|||. .|.| ...|| |.. . .|.|||||| .. .| ..|.||.| || ||.||||||| . . .||
seeyerlsrs..eetvtslks..lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsaviv
MLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKK--THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLV
|| ..... |||..|...||.. . . .. . .| . . ||||... . .|| |. ||.|. .|. . |.|||. .|.. ||..|. |..|
mltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivv
QC
|
hC
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 158-397 | 5.2e-49 | 161.6 | In-house | 1-177 (182) | alignment | ||
Range on Protein: 158-397
Range on HMM: 1-177/182.0
NKNKNRYANIVAYDHSRvvlervngdeDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTnlvglnktkCHKYWPDKTetygg
|..|||| .|. ||||| |||||||... |. . | ||| ||||. .. |.||..|.. ..||.|| .. |||..
nldknrysdilpydhsr..........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywpell.....
vtvtlhqsevfagyenctfilskekrsgSRIVRQFHFTVWPDKGVPQyATAVLAFRRKVRAlnprDAGPVIVHCSVGVERTGAYIVIDAMLEQakksrTV
| . |.... ||| ||| .|.| ..|.. . |||.|||| || |||...... |... |
............................erlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gv
DIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTE
.... . .|..||.||.| .|| |.. |.|| | ...|.
sleeavklvrsrRpgmvitpnqyfflqlallellllkktr
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 413-623 | 1.4e-48 | 161.1 | In-house | 5-213 (273) | alignment | ||
Range on Protein: 413-623
Range on HMM: 5-213/273.0
VNGKFPMTGYALEFQRLNSVTSreipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLhkehADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRM
..... .|....||..| |.. . ..||...|.|..|||..||......|| | |..|||||| .. .. ..|||||.|| .||||||||
lekllgltllleefelllslkp....lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrm
VTDYDIGTIVMLNNLHDQVAPESSEYWPDHG---ATKYGHIGISVLSKQKKGDVICVKPKVTR--KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQ
| .... .||||..|.. . |||. | ..||.. . .|| ..|.|.. . ..|. .....|.|.|. .| | ..| |.|.....|.
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvr
TSQQQC-GNVPVLVQCR
. .... .| ||.| |.
kalealpsngpvvVHCs
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 420-623 | 2.4e-48 | 160.4 | In-house | 18-217 (317) | alignment | ||
Range on Protein: 420-623
Range on HMM: 18-217/317.0
TGYALEFQRLNSVtsreiPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIG
|. ||..| |. .... ||.|.|.| .|||..||. . ..|| |. . |..|||||| . . .. ...|||||.|| .||||||||| .....
talleefedllsl.....kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvt
TIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqCGNVP
.||||..| . . . .|||. . ..||.. . .|| ....... . .|. .......|.|.|. .|.| ..|. ...||.|..|..... .. |
vivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggp
VLVQCR
||| |
vlVHCs
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 187-411 | 2.6e-48 | 160.3 | In-house | 5-244 (272) | alignment | ||
Range on Protein: 187-411
Range on HMM: 5-244/272.0
DYINASFIHGYdGT---PRSFIASQGPLPPAFEGFWRMvWEQNSQSIVMLTNLVGLNKTKCHKYWP-------------DKTETYGGVTVTLHQSEVFAG
.||||... || | |. ...|.|||| ..|||. .|.. .||.|.... ... ||..||| . | .|| ..|||.. |..
gyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
YENCTFILSKE-KRSGSRIVRQFHFTVWPDKGVPQYAtaVLAFRRKVRAlnprdAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVD--------IRN
| ...|... . . .| |...|.| ||| |||| | .|.. . ... |||.|||| |. ||| ..... .|.. .. || ...
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlylee
YLIAIRKHRPHMVQTKEQYSFIHSAVLEAlTCGNTEIQSEKYNQAMQKLA
.. .|..||..||| ||| |.. |.||. .. .... | ...|.. .
aveelraqrpgavqteeqylflyeallel.lrsllsvraeyllaaldaid
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 420-622 | 1e-47 | 157.6 | In-house | 21-219 (288) | alignment | ||
Range on Protein: 420-622
Range on HMM: 21-219/288.0
TGYALEFQRLNSVTSReipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIG
||. |.. | .. . .....|....| .|||. .|.... || |.| . ...||||| ... .......|||| || .||.|||..| ....
tgfseeynsLaalekt....ksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenkts
TIVMLNNLHDQVAPESSEYWPDHGA-TKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCgNVPV
|||||..| .. . ||||| . ..||.. . ........|.. | . .||. |. .... .|.|. .|. .. .|.||. |....|. |.
tivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpi
LVQC
.|.|
ivhC
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 413-623 | 1.1e-47 | 158.2 | In-house | 6-215 (297) | alignment | ||
Range on Protein: 413-623
Range on HMM: 6-215/297.0
VNGKFPMTGYALEFQRLnsvtSREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLhkehADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRM
..... .... ||..| . .. ..||...|.||.|||..||......|| | ||.|||||| .. .. ..|||||.|| .||||||||
lekllflalllkefeel....lpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrm
VTDYDIGTIVMLNNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQK--KGDVICVKPKVTR--KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEV
| .... .||||..| . . .|||. . .||.. . .|| .. ..|.. . .|| ......|.|.|. .| | ..| .|.||....|
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielv
QTSQQQC-GNVPVLVQCR
.. ... .. |||| |.
rkvlkllpsggpvlVHCs
|
|||||||||
DSPc_SM00195 | 425-623 | 3e-47 | 156.5 | In-house | 5-203 (263) | alignment | |||
Range on Protein: 425-623
Range on HMM: 5-203/263.0
EFQRLNSVTSREipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||..|.. || . |.. .||..| .|||...|. .. || |.||. .|.|||||| .. .. ....||||.|| .|||||||||.. .. .||||
efekleestspk....etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
NNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQKKG-DVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCgNVPVL
.. .. . ..|||. | ...|.| . . ...|| ..| . ..| .. .|..|..... .|.|. .|. .|||.|| .|..|... ..|..
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VQCR
|.|
VhCs
|
|||||||||
PTPc_SM00194 | 425-623 | 3e-47 | 156.5 | In-house | 5-203 (263) | alignment | |||
Range on Protein: 425-623
Range on HMM: 5-203/263.0
EFQRLNSVTSREipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||..|.. || . |.. .||..| .|||...|. .. || |.||. .|.|||||| .. .. ....||||.|| .|||||||||.. .. .||||
efekleestspk....etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
NNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQKKG-DVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCgNVPVL
.. .. . ..|||. | ...|.| . . ...|| ..| . ..| .. .|..|..... .|.|. .|. .|||.|| .|..|... ..|..
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VQCR
|.|
VhCs
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 421-622 | 5.3e-47 | 155.4 | In-house | 24-223 (319) | alignment | ||
Range on Protein: 421-622
Range on HMM: 24-223/319.0
GYALEFQRLNSVTSReipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
. . ||. |. .. . . .|..| .|||...|.| . .||.| . . |.|||||| |. ... |..||||| || .|.||||||| .... .
llekefkllkeavnd.....tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessi
IVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKT---HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVP
.|||..| ... . ..|||.. ..||.. . ....... |.| | |. .|. || | .. .|.|. .|. ..|.|||| ... |... . |
vvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgP
VLVQC
. | |
ivvhC
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 412-623 | 1.4e-46 | 154.7 | In-house | 24-230 (297) | alignment | ||
Range on Protein: 412-623
Range on HMM: 24-230/297.0
SVNGKFPMTGYALEFQRLNSVTSreipvEeKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHA-DEESDYINAVFLHAHRG-RNAFIATQHPLLETVEDF
.. .. .|.. |||..| |.. . .|....|.| .|||..||......|| |. | |..|||||| .. .. ..|||||.|| ||||||
llekansktllllefeellslkp.....d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedF
WRMVTDYDIGTIVMLNNLHDQVApESSEYWPDHGAtKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTS
|||| .... .||||..| . .|||. | .||.. . .|. ....... . .||.......|.|.....| | ..| ....|..|..|..
wrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrea
QQQC-GNVPVLVQCR
.... .. |||| |
laelpkggpvlVHCs
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 419-623 | 3.8e-46 | 153.6 | In-house | 26-242 (307) | alignment | ||
Range on Protein: 419-623
Range on HMM: 26-242/307.0
MTGYALEFQRLNSVTSREipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAD-EESDYINAVFL--------HAHRGRNAFIATQHPLLETVEDF
.||.. ||..|.||| . . | |....|.| .|||..||......|| |. .. . |.|||||| . . .. ..|||||.|| ||||||
ltgllkefekllsvtvfl..lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF
WRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGAT-KYGHIGISVLSKQKKGDVICVKPKVT---RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDE
|||. ......||||..| . . .|||| | . ||.. . .||......... . .|| ......|.|.|. .| | ..|. ..||...|
wrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfiee
VQTSQQQC-GNVPVLVQCR
|.. .... .. |||| |.
vrkaleelpkggpvlVHCs
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 443-623 | 2.3e-45 | 149.8 | In-house | 36-218 (314) | alignment | ||
Range on Protein: 443-623
Range on HMM: 36-218/314.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH
. | .| .|||. ||.| . .||.|. . | .|||||| .. ... .|||.||.|| |||.||||.| |.. .||||..| .. . . ..|||..
daakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPed
GATkYGHIGISVLSKQKKGDVICVKPKVTR----KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQcGNVPVLVQCR
. . ||.| . ... . . ... .|.. .....|||......|.| .|. ...|.|. .|..||.. .. ...| |
tev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCs
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 421-624 | 4.7e-45 | 149.0 | In-house | 23-228 (307) | alignment | ||
Range on Protein: 421-624
Range on HMM: 23-228/307.0
GYALEFQRLNSVtsrEIPvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
|.| |...|.. ||. . .|.|| |. |||. ||.| .. ||.|.| .|.|||||| |..... .. ||| | |. .|..|||||... .. .
glakeyekLear...eid.kstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtl
IVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKK-------KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC
|||| || .. . . |||. ..||.| . . |..|..| | . .|..|| ....| |. .| | .|.|.|..|.|...|. ...
ivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln
gNVPVLVQCRY
. |..| |.
.rsPivvhCsa
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 443-622 | 6.8e-45 | 148.4 | In-house | 51-235 (330) | alignment | ||
Range on Protein: 443-622
Range on HMM: 51-235/330.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH
. .| .| .|||. .|. . ||.| . . |||||||| |.. .. .. |||.| |. |||||||||. ... ||||| .|... ||||.
elaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPde
GATKYGHIGISVLSKQKKGDV----ICVK--PKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNvPVLVQC
|. ||.| ..| .. |. ..|. |. ||.||. || .| || | .| .. .|.|| .|.. .|| .. |. | |
GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhc
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 397-622 | 8.5e-45 | 148.0 | In-house | 6-225 (293) | alignment | ||
Range on Protein: 397-622
Range on HMM: 6-225/293.0
EIQSEKYNQAMQKLASVNGkfpmTGYALEFQRLNSVTSREipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFI
.|. ||... ..|... . .... |...|..| . . .... |...| |||...|.. . || |.. . ...|||||| ... .. .. ||
piklekfeehvkkmkadsd....lrfseeyeelkavgkdq....avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefi
ATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH-GATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKV
||| || |||.|||||| . .|||| .| .. ||||.. .. ||.| ......... | .. . |....|....||..|..||.| .|.
atqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPek
SRSVLDLLDEVQTSQ-QQCGNVPVLVQC
....||.. .|.... ... . |..| |
tktlldfvrtvreaiektaskrPivvhC
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 414-623 | 1.1e-44 | 148.4 | In-house | 14-218 (278) | alignment | ||
Range on Protein: 414-623
Range on HMM: 14-218/278.0
NGKFPMTGYALEFQRLNSVTSreipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMV
.. |.. |||..|.|.. ...|....|.| .|||..||......|| |. . |. |||||| .. .. ..|||||.|| ||||||||||
lllnlktllllefeellsfkl.....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmv
TDYDIGTIVMLNNLHDQVAPESSEYWPdHGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQ
.... |||||..| . . . .||| | ..||.. . .|. ....|.. . .|| .......|.|.|...| | ..| ..||.| .|.. ..
welgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale
qCGNVPVLVQCR
| |||| |.
.dsngpvlVHCs
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 421-622 | 5.3e-44 | 145.2 | In-house | 9-214 (290) | alignment | ||
Range on Protein: 421-622
Range on HMM: 9-214/290.0
GYALEFQRLNSVTSREI--PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDI
.| |||.| ..... | ....|||..| .|||. ||. . ||.|.|.. .|.|||||| |.. |. ..||.| || .|..|||||. ....
efakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknv
GTIVMLNNLHDQVAPESSEYWPDHGAT--KYGHIGISVLSKQKKG-DVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqCGN
.||. .. . |||..| . ..|.. ... .... | . ||...|....|. .|. .| |. .|. |.|.|...|.. |. .
eivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sed
VPVLVQC
.|..| |
aPlvvhC
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 450-623 | 1.3e-43 | 144.5 | Pfam-A | 1-178 (235) | alignment | ||
Range on Protein: 450-623
Range on HMM: 1-178/235.0
NLHKNRFSDIIALNSCRVMLhkEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKY
|..|||..||.. .. || | .. ...|||||| ... .. ..|||||.|| .|.|||||||..... .||||..| .. . ..||| ... ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GHIGISVL-SKQ-KKGDVICVKPKVTRKKKT---HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqQCGNVPVLVQCR
|.| . . ... .. ... | ... ||. .||..||. .|.|...|. ..|.|||...|..|. . . ||.|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCs
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 450-623 | 1.3e-43 | 144.5 | In-house | 1-178 (235) | alignment | ||
Range on Protein: 450-623
Range on HMM: 1-178/235.0
NLHKNRFSDIIALNSCRVMLhkEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKY
|..|||..||.. .. || | .. ...|||||| ... .. ..|||||.|| .|.|||||||..... .||||..| .. . ..||| ... ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GHIGISVL-SKQ-KKGDVICVKPKVTRKKKT---HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqQCGNVPVLVQCR
|.| . . ... .. ... | ... ||. .||..||. .|.|...|. ..|.|||...|..|. . . ||.|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCs
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 187-384 | 2.1e-43 | 143.3 | In-house | 3-163 (174) | alignment | ||
Range on Protein: 187-384
Range on HMM: 3-163/174.0
DYINASFIHGYDGTPrSFIASQGPLPpafegFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDktetyggvtvtlhqsevfagyenctfilskEKRSGS
||||||..... || .||.||||. ||.|..|......|||.... |...||. |||. . . .
dyinaspldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredle
RIVRQFHFTVWPDKGVPQYATaVLAFRRKVRALNPR-DAGPVIVHCSVGVERTGAYIVIDAMLEQAKkSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIH
| . |.... ||| ||| .. .| | . |. . . |||.|||| || |||. .... || . . ...||. ... ..|..||.|||| .|| |..
rlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 443-623 | 5.8e-43 | 142.4 | In-house | 2-184 (245) | alignment | ||
Range on Protein: 443-623
Range on HMM: 2-184/245.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH
||...| | .|||.|||......|| | . |. |||||| . . .| . |||||.|| |||||||||. ...| |||||..... . . .|||..
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
GATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
. ..||.. . .|| ....|... . .|| ......||.|.|...| | ..| ....||.|..|.. .....| |||| |.
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCs
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 442-623 | 2e-42 | 140.9 | In-house | 3-187 (249) | alignment | ||
Range on Protein: 442-623
Range on HMM: 3-187/249.0
KSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD
.||...| |..|||..||......|| |. . |||||| ... . ..|||||.|| |||||||||. ...|..||||..| .|||.
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
HGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC-GNVPVLVQCR
| ..||.. . .|| ..|.|... . ..| ......|.|.....| | .|. ..||....|.. .... . |||| |
ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCs
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 418-622 | 1.2e-41 | 137.6 | In-house | 13-215 (281) | alignment | ||
Range on Protein: 418-622
Range on HMM: 13-215/281.0
PMTGYALEFQRLNSVTSREIPVeeksVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYD
.|.. |.. |... .. . ....| .|||.|.|.| . || ..........||||| |. . .| ...|||| |. .....||.|| ...
dnaGfieeyeklaaigvdntat....askadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqk
IGTIVMLNNLHDQVAPESSEYWPDHG-ATKYGHIGISVLSKQKKGDVICVKPKV-TRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGN
. .|||. . .. ||||. ..|||.. .. .....| |. | |. ... .| ||..|....| |. .|. .. .|. .||. ... .
vsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktk
VPVLVQC
.|... |
aplvihC
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 440-622 | 7.8e-41 | 135.2 | In-house | 36-223 (305) | alignment | ||
Range on Protein: 440-622
Range on HMM: 36-223/305.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYW
| ||.| .| .|||...|. |. |..| ... ...|||||| ...........|..| || .||.||||.. .. . ||||| .| .. ||
esidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYW
PDHGAT--KYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQC
|. . ..|.. . . |... | | | |.. .|... | ... .| |. .|. . |.|.|...|| .|.. .||.|| |
pesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhC
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 145-391 | 1.2e-40 | 134.5 | In-house | 28-277 (307) | alignment | ||
Range on Protein: 145-391
Range on HMM: 28-277/307.0
QFPWGAARKPANKNKNKNRYANIVAYDHSRVVLErVNGDeDLDYINASFIhGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKC
. | | . . . | .|||| .. . |..|.|.. ..| ||| | .. | |. ||..|||| . || |. ... .|..|| ... | | ||
ktpegvtveafsantdknryqdvkcqdkgrivvk.fdgl.asdyihanyl.giaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikc
HKYWPD---KTETYGGVTVTL----HQSEVFAGYENCTFIL--SKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFrrkVRALNpRDAGPVIVHCSVGV
..||| .. ..| . |. .. .| |.. . . ..|| .... .. |||.|||| . . . . | . | ||.|||| ||
eqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainl...leavr.ydtnpvvvhcsaGv
ERTGAYIVIDAMLEQAKKS-RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
|.|. . | . .. . |... . .|..|.. .||. || ..| .|| .
GrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 438-623 | 2.1e-40 | 134.3 | In-house | 21-214 (278) | alignment | ||
Range on Protein: 438-623
Range on HMM: 21-214/278.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMlhkehadeesDYINAVFLHAHrgRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSE
.. | ... .. ||.|||..||......|| ||||| ... . ...|||||.|| .||.|||||. ...| .||||..|.. .
ipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaq
YWPDHGATKYGHIGISVLSKQKKGDVICVKPKVT------RKKKTHEVRHLHHVSWTDKCIPKVS--RSVLDLLDEVQTSQQ------------QCGNVP
|||..| ||.. . .|| . .|.. .. .|| ....|.||| ..| | ..| . .|.|.||.... .. . .. |
ywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggp
VLVQCR
||| |.
vlVHCs
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 155-389 | 3.8e-40 | 132.4 | In-house | 51-281 (290) | alignment | ||
Range on Protein: 155-389
Range on HMM: 51-281/290.0
A--NKNKNKNRYANIVAYDHSRVVLErvNGdEDLDYINASFIHGydgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT
| . .|||| ..| | .||.|. .| | ||. | ...| . || .||.| . .|||| ... |||| .|. |.||..|.|.|
fdkntefkknrykdvvcndktrvilk..dG.ydGdyvhanyvkG...lkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypeke
---ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALnprdAGPVIVHCSVGVERTGAYIVIDAML
|.| .||. ... . ..| || . ... .. |||| |.. . |.| | .| . .|||.|||| |. |||... |.. |
GevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrtGtfvaievgl
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
. . . .|. . |.|. | || || . ..|.
qilldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 439-623 | 3.9e-40 | 132.8 | In-house | 40-225 (297) | alignment | ||
Range on Protein: 439-623
Range on HMM: 40-225/297.0
VEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGrnAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVApESSEY
. .. | || |..|.|...|. .| ||.|. | .|||.|| |... . .|.|| | .||.|||.|| |... ||||||..... . |
iqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcary
WPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPK--VSRSVLDLLDEVQTSQQQCGNVPVLVQCR
|.|.| |..|.. . .|| ... | . .||. | ... |. ..|.| || ... .|.|.|..||. . .| . |.|| |
WsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhcl
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 180-389 | 9.3e-40 | 131.6 | In-house | 6-171 (176) | alignment | ||
Range on Protein: 180-389
Range on HMM: 6-171/176.0
VNGDEDLDYINASFIHGYDgtprsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETYGgvtvtlhqsevfagyenctfils
|.|||||||..| |. .|| ||||| .. |..|..|.. . .|.||..| |.. ||. |||. ..
lgldldldyinanlilgsr.....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.......................
kekrsgsrivrQFHFTVWPDKGVPQYaTAVLAFRRKVRALNPRDaGPVIVHCSVGVERTGAYIVIDAMLEqakkSRTVDIRNYLIAIRKHRP-HMVQTKE
|.... ||| |||.. ...| . . .| .. |||.|||| |. |||...... . .. ... . | .|..|| ..||| |
...........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpe
QYSFIHSAVLE
|| |.. ..|.
Qyrflyefell
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 420-624 | 9.4e-40 | 131.3 | In-house | 19-229 (563) | alignment | ||
Range on Protein: 420-624
Range on HMM: 19-229/563.0
TGYALEFQRL-NSVTSREIPVEEksvGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEES-DYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYD
.|.. ||. | . ..|.....| .||.| .||| ..|.| .. || |.. ... ||||| ... .. .||||||.|| .|..|||||. .
igfseefealqsetiskdldaeh...sqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqn
IGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKG----DVICVKP-KVTRKKK---THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTS
.|||. || .. . . ||| .. .||.. . ..... . .| |. .||. ..||. | .| |.. |. | || ...
vaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaa
QQQ-CGnvPVLVQCRY
... | |..| |..
nkaeaG..PivvHcsa
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 444-623 | 1.1e-39 | 131.2 | In-house | 43-220 (315) | alignment | ||
Range on Protein: 444-623
Range on HMM: 43-220/315.0
VGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHg
| | .| .|||. .||| . || | |..|||.|| |. . .. .||.| |. ..|.||||.| ..|||.||||.|| .. . .||||.
vakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.
ATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGnVPVLVQCR
||.| .. |.... .. . |. ... .|| ||. || | .|| . ....| |. ... ...| |.
kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcs
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 157-392 | 6.1e-39 | 130.0 | In-house | 45-281 (314) | alignment | ||
Range on Protein: 157-392
Range on HMM: 45-281/314.0
KNKNKNRYANIVAYDhSRVVLERVNGDeDLDYINASFIHGYdgtpRSFIASQGPLPPAFEGF----------WRMV--WEQNSQSIVM------------
.|..|||| .|. .| .||.| ..... . ||||||...|. ..|||.||||. .. | |||| ...|. |||
lnrdknryldilpad.nrvilpglpvs.gsdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsr
---------LTNLVGLNKTKCHKYWPDKTetyggvtvtlhqsevfagyenctfilSKE--KRSGSRIVRQFHFTVWPDKGVPqYATAVLAFRRKVRALnp
|..| |.. . ..... . . .| . ... . .|| ..| ...| . ....
LdaAlgKtpllildgngneptaadlellk..........................eelydpelferlgikylripvpDgsap.lledfdeflefieea..
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKksrtVDIRNYLIAIRKHRP-----HMVQTKEQYSFIHSAVLEALT
.. |||.|||. |. ||| ..|.. .. . . |... | .|. || ..... ||| ||. |.||.|
dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 183-384 | 9.4e-39 | 128.2 | In-house | 2-154 (172) | alignment | ||
Range on Protein: 183-384
Range on HMM: 2-154/172.0
DEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLvglnktkchkywpdktetyggvtvtlhqsevfagyenctfilSKEK
||. ||||||....| ..| ||| ||||. .. ||||..|.. . ||.||.| . .
degsdyinasyldlyyipdr.fiatqgplrntladfwrmlkelgithivnltel..........................................lydp
RSGSRIVRQFHFTVWPDKGVPqYATAVLAFRRKVRA-LNPRDAGPVIVHCSVGVERTGAYIVIDAMLeqakksRTVDIRNYLIAIRKHRPHMVQTKEQYS
.| . |.... ||| ||| . .| | . .. |. .. |||.|||| || |||. .... || . ... . . .|..||..||...||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
FIH
|..
fly
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 444-624 | 2.8e-38 | 127.3 | In-house | 4-187 (243) | alignment | ||
Range on Protein: 444-624
Range on HMM: 4-187/243.0
VGEKPQNLHKNRFSDIIALNSCRVMLhkehadEESDYINAVFLHAHrGRnaFIATQHPLLETVED----FWRMVTDYDIGTIVMLNNLHDQVAPESSEYW
.. .|.||.|||.|||.... || | | |||||| . .| .||||.|| ||||| ||||. ...|..||||..| . . .||
iallpenlsknrysdilpydhsrvkl......egsdyinanliyvt.pr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PdhGATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ-------CGNVPVLVQCRY
| | . ||.. . .|| . ..|.. . .... .. |..|.|.|...| | ..| ..||.||||.. ... .. |||| |.
p..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsa
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 443-612 | 5.1e-38 | 125.8 | In-house | 35-208 (297) | alignment | ||
Range on Protein: 443-612
Range on HMM: 35-208/297.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--
. ... ||.|||..|.. ... ||.| |.. ||.|||||| |. .. ..|||||| || .||.|||||| . .. .||| . .. ..|||
lasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWple
DHGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ
.. ....|.. .|... ... | . ... ..... .| | .|| | .|. . |.||.|..|. | .
eessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqal
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 396-622 | 6.4e-38 | 125.5 | In-house | 2-234 (306) | alignment | ||
Range on Protein: 396-622
Range on HMM: 2-234/306.0
TEIQSEKYNQAMQKLASVNGKFPMTGYALEFQRLNSVTSREipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHkEHADEESDYINAVFLH--AHRGRN
|.. ... .| ...| . .. .|. ||..|. ... . ... |.||.| .|||. |. . ||.|. |. .|||||| ... .. ..
tsllakeieqrvselekeeeslekagfeeefeelqqeeakk..llsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdk
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGAT-KYGHIGISVLSKQKKGDVICVKPKVT---RKKKTHEVRHLHHVSWTD
..|||| | .||.|||||| . . |||. . .. . ||||. .. .||.| .. .|.... | | . .|. .||...||...|. || |
syiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPd
KCIPKVSRSVLDLLDEVQTSQQQCG---NVPVLVQC
. .|| |||.|..|.. |... . |..| |
hgvpkdpgavLdfledvnrkqeeleeaeagpivvhC
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 443-623 | 1.2e-37 | 124.2 | In-house | 36-217 (515) | alignment | ||
Range on Protein: 443-623
Range on HMM: 36-217/515.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD-
.| .. | .|||. .|. ..| || | . . .|||.|| .... .|.||.| |. .|.||||.| .... ||.|...|... ..||||
tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdk
-HGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGnVPVLVQCR
. |.|.| ....| . .. | | .|.. .... | | | || .|| ..|.| |. ||.....| |... |
pgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcs
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 154-389 | 1.7e-37 | 123.9 | In-house | 29-257 (267) | alignment | ||
Range on Protein: 154-389
Range on HMM: 29-257/267.0
PANKNKNKNRYANIVAYDHSRVVLERVNGDedldYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNlVGLNktKCHKYWPDK--
|.||...||. . . ||..||.| . . |||||...|| | . ||. |.|| . |. .. .|. ||.||. |. . . ...|| |
iaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyk.tknafivtqdplkntitdfltvihdqkvpvivlltk.vftd..nirlfwPPkmg
-TETYGGVTVTLHQSEVFAGYENCTFILSKeKRSGSRIVRQFHFTVWPDKG-VPQYATAVLAFRRKVRALNprDAGPVIVHCSVGVERTGAYIVIDAMLE
.. | .|| . |. |. | | .. | ... | . | ... | . | |..|.|| || |.|...|||..||
qakkyqdltvehslekeendyqiitlelkf.knesahnvtlyyykkwnintnnkpylkplfgilaknqlen..gnrPlvvacsdGvGrsGtflvidsqle
QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.||. ..|| ..| ||. |. .|.|||.| .|| . |
raktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 438-623 | 2.7e-37 | 123.3 | In-house | 32-218 (315) | alignment | ||
Range on Protein: 438-623
Range on HMM: 32-218/315.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSE
.. .. |. ...| .|||. .|. |.| ||.| . .|||||| .... .|.||.| || .|.|||||| .... ||||....... .
diyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrq
YWPD--HGATKYGHIGISVLSKQKKGDVICVKPkVTRK-KKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSqQQCGNVPVLVQCR
|||| ....| | ...|| . .| . | |||| .... | . | || ..| . |.| |. ||... .. . ..|| |
ywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcs
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 421-622 | 5.5e-37 | 122.6 | In-house | 24-228 (325) | alignment | ||
Range on Protein: 421-622
Range on HMM: 24-228/325.0
GYALEFQRLNSVTSReipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
|.| ||. | |. . | | ||.| |||| ...||. ||.| . | .|||||| .|. ..... |.|.| || .|..|.||.| |.
gfahefgllpsddgi.....akkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsv
IVMLNNLHDQvAPESSEYWPDH--GATKYGHIGISVLSKQKKGDVICVKPKVTRKKK--THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ----
.|.|| | . . . |||.. . ..| . ... . .. | . . .| . || | |. ... || | .| ... .|. |.. ...
vvvlneldlg.kdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtan
-CGNVPVLVQC
. |.|| |
tkastpilvhc
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 201-384 | 6.9e-37 | 121.8 | In-house | 8-143 (152) | alignment | ||
Range on Protein: 201-384
Range on HMM: 8-143/152.0
PRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWpdktetyggvtvtlhqsevfagyenctfilskekrsgsrivrQFHFTVWPDK
|. ||| |||.| .. ||||..|.. . |||||.|. |.| ||..|. |.... |||
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qylhlpwpDh
GVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLeqakksRTVDIRNYLIAIRKHRPHMVQTKEQYSFIH
|||. . .| . . .. |. .. |||.|||| || |||...... || . |.. ... .|..||..|....|. |..
gvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 419-622 | 2.2e-36 | 120.3 | In-house | 19-218 (287) | alignment | ||
Range on Protein: 419-622
Range on HMM: 19-218/287.0
MTGYALEFQRLNSVTSREipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHkehaDEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDI
.|. |. |..|| || .| .. .|| .|||...|. . ||.|. .|. |||||||. ... ..|||... |. .|. .||... | .
negfknqftvleqvtqre...devthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnv
GTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKK---THEVRHLHHVSWTDKC-IPKVSrSVLDLLDEVQTSQQQCG
.|||| ..... .|||.. .. .|. |..|..... ..| | .|..|.| ...|. . .| .. ... ..| ...| .|.. |
taivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepq.tillvieemyktqrkrg
NVPVLVQC
| ...| |
ntsivvhC
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 170-388 | 9.7e-36 | 118.4 | In-house | 2-168 (178) | alignment | ||
Range on Protein: 170-388
Range on HMM: 2-168/178.0
YDHSRVVLERVNGDEDLDYINASFIHGYdgtprSFIASQGPlppafEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTEtyggvtvtlhqsevfa
.|..||.|. . | | ||||||.| .. ...|..| . ......|.. ..||.||. . |.. ||..|||....
ldrtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
gyenctfilskekrsgsrivRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQakksrTVDIRNYLIAIRKH
|.... .|| |||. .|.| . .... ... |||.|||| || |.|. .... |... ... . . .|..
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RPhMVQTKEQYSFIHSAVL
|| .|.. .|. ... |
Rp.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 125-390 | 1.4e-35 | 117.5 | In-house | 18-286 (305) | alignment | ||
Range on Protein: 125-390
Range on HMM: 18-286/305.0
AKMHGGIRLET-EYKKFNNgqqFPWGAARKPANkNKNKNRYANIVAYDHSRVVLervNGDEDLDYINASFIHGyDGTPRSFIASQGPLPPAFEGFWRMVW
|. |.| | |.||. | | | |. ...|||| .. |. || | .| .|| | .. |. || .| || . || | .
ekgpaglraefvamkrfnd...fekmkafkeaq.eagknrykdvgcldnnrvkl...egpwpheyihanyvst.ptnpkrfictqaplektcadfwymcl
EQNSQSIVMLTNLVGLNKTKCHKYWPDKT-------ETYGGVTVTLHQSEVFAGYENC------TFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVL
... ..| || ||. ||..|.. | | ..| . |. . ... | .. . . .| | ..|. |||.||| .|.|
qdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlail
AFRRKVRALNprdaGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIR-NYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
. | |.. ||..|||| |. |||. .... .|.| . .. | ||. | .|| .|| |.| .|.
ellekarpsk....gpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilny
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 441-622 | 4.2e-35 | 116.0 | In-house | 32-215 (280) | alignment | ||
Range on Protein: 441-622
Range on HMM: 32-215/280.0
EKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEhadeESDYINAVFLHAHR----GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESS
. |. ||.||.|||. ||.. .. ||.|... |.||||| .. | .|||| || .|..|||.|| . .. .|||| .| ..
aisaarkpenlsknryrdilpydatrvklkes....etdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkCh
EYWPDHG-ATKYGHIGISVLSKQKKGDVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqQCGNVPVLVQC
.|||... ..||.. . . ..... .. . ...|. . ... .| ...|.|...|. | ..|.....|.. . . . ||.| |
qyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr.sgkeePvvvhC
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 419-622 | 7.3e-35 | 115.2 | In-house | 19-223 (290) | alignment | ||
Range on Protein: 419-622
Range on HMM: 19-223/290.0
MTGYALEFQRLNSvTSREIPVeekSVGEKPQNLHKNRFSDIIALNSCRVMLH--KEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDY
..|. .|..|.| ...| | || ..| ..|||..|. . |..|. .| | . .||||.... .. ....|||| |. .|. |||... .
negfrnqfkmlds.gesehtv...tvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqe
DIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKK---THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC
.. |||| | .. . ||||.....||.. | .|. .. . | | .|. |.. ...| ... .| .. . ..| .. |.. | .
kvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkr
GNVPVLVQC
|| ...| |
gntsivvHC
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 420-622 | 1.9e-34 | 113.8 | In-house | 15-219 (288) | alignment | ||
Range on Protein: 420-622
Range on HMM: 15-219/288.0
TGYALEFQRLNSVTSREipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHkehaDEESDYINAVFLHAH-RGRNAFIATQHPLLETVEDFWRMVTDYDI
|. .|. |.. .| ...|. . .|||. ||. .. ||.|. ... ||||| |.. | ||||| || .|. |||.|| .
taldkkfkeleqkqdke..arkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqks
GTIVMLNNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT---SQQ
.|||| . ... |. ..||| . ..|.|.. ... |... . .. . |.. .......|.||. ||.. .|. ..|..||||.. ..|
sviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavq
QCGNVPVLVQC
. ..|..|.|
rksktPlvvhC
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 437-622 | 3.4e-34 | 113.2 | In-house | 14-208 (274) | alignment | ||
Range on Protein: 437-622
Range on HMM: 14-208/274.0
IPVEEKSV-GEKPQNLHKNRFSDIIALNSCRVMLHKEHADEE-SDYINAVFLHAHRG-RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAP
.|.. . . . . .|||. .|. . ||.|..|....| |.|||| ... .. .|..||| || .||.|||||. .. |||| .|...
lPlnfdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneq
ESSEYWPDHGAT----KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNV--PVLVQC
..|.||. . .||.. | | .. .. | | . .....| | . .| |. |. ...|||..||..|... . ||.| |
kCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhC
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 150-390 | 9e-34 | 111.5 | In-house | 47-288 (305) | alignment | ||
Range on Protein: 150-390
Range on HMM: 47-288/305.0
AARKPANKNKNKNRYANIVAYDHSRVVLERVNgdeDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP
| . |. .. ||||... . |.| | |.. . ||| | .. . ||..|||| . . || || ... . |||| . | | | || .|||
nanqsadiaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywp
----DKTETYGGVTVT-LHQSEVFAGYENCTFILSKEKRSGSR--IVRQFHFTVWPDKGVPQYATAVLAFRRKVRAlnprDAGPVIVHCSVGVERTGAYI
.| | .|. | . | . . | . ||.. ||....| |||.||| . | . .| |..|||| |. |||. .
aaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairg....skvpivvhcsagigrtgtiv
VIDAMLEQAKKSR-TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
|. .||. . . . . . |.| .| . .|. || ||| .|.
aieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 157-317 | 1.4e-33 | 110.9 | In-house | 27-191 (319) | alignment | ||
Range on Protein: 157-317
Range on HMM: 27-191/319.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD-----K
|.|.|..|.| ..||||.|. |. |..||.. ||| .| |.||.| .| . |||.||||.|. || ||.| | .| .|.|
tskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldn
TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFtVWPDKGVPQYATAVLAFRRKVR
|..|| . ||| . || | |..| . ... || . . . |.. .|| .|..| .||
tslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 423-622 | 1.5e-33 | 111.5 | In-house | 37-231 (319) | alignment | ||
Range on Protein: 423-622
Range on HMM: 37-231/319.0
ALEFQRLnsvTSREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIV
||.|. . . .. ... . .|| |||. .|.| . .| |.. | |||||| |. .. .. .||.| || .|..|||||. .|.. |||
evefrra...cklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstiv
MLNnlhdqvAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT-SQQQCGNVPV
.| |.||| .. |... ..| | .. . . . .... .| ... | | |. |. . .. |.. |. ... .. ..
llt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhrani
LVQC
.| |
vvhc
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 434-622 | 3.4e-33 | 110.3 | In-house | 9-195 (284) | alignment | ||
Range on Protein: 434-622
Range on HMM: 9-195/284.0
SREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNnlhdqvAP
. .. ... . .|| |||. .|.| . .| |.. | |||||| |. .. .. .|||| || .|..|||||. .|.. |||.|
klgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kd
ESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT-SQQQCGNVPVLVQC
|.||| .. |... ..| | .. . . . .... .|. ..| | | |. |. . .. |.. |. .... .. ...| |
kcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhc
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 157-389 | 9.6e-33 | 108.0 | In-house | 36-267 (281) | alignment | ||
Range on Protein: 157-389
Range on HMM: 36-267/281.0
KNKNKNRYANIVAYDHSRVVLER-VNGDEDLDYINASFIHGyDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTE--
|..||||.|| . | ||| |. . . ||| | .|. | .| .||| . ||||.|..|. .|||| ... |. || .|.| ..
vnnkknrylnipcldisrvqlkvkmpnknstdyihanyirs.pflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcc
-TYGGVTVTLHQSEVFAGYENCTFILSKEkrSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAlnpRDAgPVIVHCSVGVERTGAYIVIDAMLEQAK
. ..|. .| | . || | .|.. .. . ||| ||. . .| ||.|| | . | ..||| || |.|. . .. |. .
lqfdklsvsyedstvnkslvttrlnlsye..getrlithwlwkewpdwqvpessevmlkilrkira...rst.ppvihcsagvgrsgtlmaveialqsih
KSRTV-DIRNYLIAIRK-HRPHMVQTKEQYSFIHSAVLE
|. ||.. . .| | ||| .|| .| .|.
shftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 153-399 | 1.9e-32 | 107.1 | In-house | 47-297 (310) | alignment | ||
Range on Protein: 153-399
Range on HMM: 47-297/310.0
KPANKNKNKNRYANIVAYDHSRVVLErVNGDEDLDYINASFIHGyDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD--
. .|. ||||...| | ||| |. .. ||| | ... . .|| ||||| . ||||.... ..||..| . . . || |||
eaykkymhknrysdvvcldtsrvklk.idksryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslg
KTETYGGVTVTlHQSEVFAGYENC----TFILS----KEKRSGSR--IVRQFHFTVWPDKGVPQYATAVLAFrrkvRALNPRDAGPVIVHCSVGVERTGA
||||| . || || .| | ||. |. . . | .. |||.|||. . | | ||..|||| |..|...
vtetygcirvt.nlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpq....rllaqvrhgpcvvhcsagkdrlyv
YIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLeALTCGNTEIQ
. .. ...... ||. . ..|.| .||. || .|. . ... |.||.
vvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvri.ifargeteva
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 272-415 | 4e-32 | 106.1 | In-house | 78-218 (440) | alignment | ||
Range on Protein: 272-415
Range on HMM: 78-218/440.0
ENCTFILSKEkrsgSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALN-PRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHR
|...| . | || ..|.|. |||||||..| || . . | . ||..||||.|. ||| |..|..| .||.| .|| ... ..|. |
inasyingie....srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnr
PHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLASVNG
|.|||| |||.|.| ||||.| ||.| | . . .... |
pqmvqtpeqyafvheavlegllcgdtliledditerveqiqwpnp
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 186-388 | 4.4e-32 | 106.1 | In-house | 3-150 (151) | alignment | ||
Range on Protein: 186-388
Range on HMM: 3-150/151.0
LDYINASFIHGYdgtprsFIASQGPLPpafeGFWRMVWEQNSQSIVMLTNLVGLNktKCHKYWPDKTetyggvtvtlhqsevfagyenctfilskekrsg
||||.|.. |. ...|.|||. |.....|.. ..||.|.... . .|..|.|.
sdyinfsyvtgg......lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
sRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAlnpRDAGPVIVHCSVGVERTGAYIVIDAMLEQakksrtVDIRNYLIAIRKHRPHMVQTKEQYSFIHS
. |...... ||| |.|.. |||.| ..... . |||.|||| |. |||. .... ||.. |.. | .|..||..||...|. |..
.ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
AVL
|.|
all
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 440-623 | 5.3e-32 | 105.7 | In-house | 46-232 (297) | alignment | ||
Range on Protein: 440-623
Range on HMM: 46-232/297.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRN-AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
. |.|.....|..||| ..... . || |..| ..|.|||||| .. | |. |.|||| || .|| |||.|| . . ||.| .|... . ..|
stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry
WPDHGATKYGHIGISVLSKQKKGDVICVKP---KVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQcGNVPVLVQCR
|||.|. |. . ..|. | |. | ....| | .|..||... .| ..|.|.. |. | . |..| |
wpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcs
|
|||||||||
PTPc_DSPc_SM00012 | 289-389 | 1.1e-31 | 104.5 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 289-389
Range on HMM: 2-105/105.0
VRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDA--GPVIVHCSVGVERTGAYIVIDAMLEQAKKS-RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHS
|...|.| |||.|||......| . |.|. . . .||.|||| || ||| ....| .|.| .|. ..||| ... ..||.||.||||.|||.|..
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVLE
|.||
alle
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 155-349 | 1.7e-31 | 104.4 | In-house | 44-254 (418) | alignment | ||
Range on Protein: 155-349
Range on HMM: 44-254/418.0
ANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGydGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET
..| .||||.||. .|.|| |.... | ||||| .| | |. ||..||||| . |||||||. . ||||. . || .|||..
kkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg..aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigg
yGGVTVTLHQSEVFAGYE--NCTFILSKEK-----------RSGSRIVRQFHFTVWPDKGVPQYATAVLAF-----RRKVRALNPRD-AGPVIVHCSVGV
... ||| | | |. .| . |... |||. .|... . . |. . . | |.||||| ||
.eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagv
ERTGAYIVIDAMLE
|||.. |..
grtgtfctavimmk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 440-622 | 3.9e-31 | 103.0 | In-house | 10-204 (270) | alignment | ||
Range on Protein: 440-622
Range on HMM: 10-204/270.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLH-AHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
.|... | .. . ||. ||. ||.|.... |... |||| ... .. ....||.. || |...||||. . .|||. .|... . . |
sesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerY
WPDHGAT----KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSR------SVLDLLDEVQTSQQQCGNV-PVLVQC
|| . . ..|.| . .||..|. | . ....| ..... | ....| |. .|. . ..| .| .|. |... . |.|| |
WpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHc
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 424-623 | 1.7e-30 | 100.9 | In-house | 10-207 (283) | alignment | ||
Range on Protein: 424-623
Range on HMM: 10-207/283.0
LEFQRLNSVTsreIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAdeesDYINAVFLH---AHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
| ...|. .. .| . . .| .|||. .|.. . || |. | |||||||. .. . .|..| || .|| |||.|| | .| .
lfrevlkrls...vpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekita
IVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRK---KKTHEVRHLHHVSWTDkCIPKVSRSVLDLLDEVQTSQQQCGNVP
|||| .| .. . | ||| .|. .|| ... . | . . . |.| . | . |.. . .. | .. |.. |.. . |
ivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWle.ygeqaiinslvkfnkvislqteskkgP
VLVQCR
..| |
ivvhCs
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 157-399 | 2.6e-30 | 100.5 | In-house | 42-279 (288) | alignment | ||
Range on Protein: 157-399
Range on HMM: 42-279/288.0
KNKNKNRYANIVAYDHSRVVLErvngdEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETY-
.| ..|| |. | .|| |. .| |. |. . .| .| .| || . | .|.|. |.. . ||||..|. . | | .|.| |
anptrdryenlprcditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGeka
--G-GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNprdaGPVIVHCSVGVERTGAYIVIDAMLEQAK
| ||. .. . . . . ... . ||.. |. |.|.|||. . | . ...|. |..||.| || |||. |.| .||...
rigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslq....kPivvhssaGvGrtgtlililialeslr
KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
. . ||. | |..| . .||. || ..| ||| | . .
lddflgirsllaklreerfkaiqtemqylyvhrcvleelllkkykvl
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 156-397 | 7.7e-30 | 98.7 | In-house | 41-282 (312) | alignment | ||
Range on Protein: 156-397
Range on HMM: 41-282/312.0
NKNKNKNRYANIVAYDHSRVVLervNGDEDLdYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTety
| |. ||| || .| | | |||.. || | |.. | |...|||| . ||... | ||..|. .| || || |
lkfkdlnrypniqcwdrgrftl...agdenf.yihanfvkic.tkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdiv...
GGvtVTLHQSEVFAgyENCTFIL----SKEKRS-----------GS-RIVRQFHFTVWPDKGVPQYATAVLafrRKVRALNpRDAGPVIVHCSVGVERTG
| | | . |.. | || | ||.| . | . .. .. |||.|.|. . | | . |.. .| ||| ||| || |||
gf..vdledhrvyt..eycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtal...rllsavk.kdkkpviahcsagvgrtg
AYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTE
. ..|..|. .. | .... .. .|| | |.. || . .||| | .
tlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 150-315 | 2.7e-29 | 97.0 | In-house | 27-192 (297) | alignment | ||
Range on Protein: 150-315
Range on HMM: 27-192/297.0
AARKPANknKNKNRYANIVAYDHSRVVLERVNGDEdlDYINASFIHGY-DGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYW
.|.... |||| .|.|.| .|| | || .. ||||| .. . .. .| .|||| . . ||..|.||. . |||...| . || ||
sakrnss..lrknryrdilatddtrvkllrviter..dyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapyw
PDKTE--TYGGVTVTLHQSEVFAGYENCTFI-LSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRK
|. . | | . |.. ... . | || || || | |||.||| . |. .
psvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaq
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 420-623 | 4e-29 | 96.2 | In-house | 13-231 (296) | alignment | ||
Range on Protein: 420-623
Range on HMM: 13-231/296.0
TGYALEFQRLNSVTSReIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIG
. .|.. . .|.| . .. | . .|. ||| ... . ||.|.| . .|.|||||||. .. ...| |. | |||..|||.| | .|
rkfrveyklelkltpr.leigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeis
TIVMLNNLHDQVApESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRK------------KKTHEVRHLHHVSWTD-KCIPKVSRSVLDLLDEV
..|.| . |. .||| .. ..||.| . ...... .. . |.|.| .| |.... | . .| .. ....|. |
avvvLtktfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrv
QTSQQQC----GNVPVLVQCR
.. ... . ||.| .
rlwrekvdedpeegPvvvvss
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 156-391 | 5.7e-29 | 96.0 | In-house | 33-270 (285) | alignment | ||
Range on Protein: 156-391
Range on HMM: 33-270/285.0
NKNKNKNRYANIVAYDHSRVVLErvngDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTE--
. | . ||||.. . . .||||. . | ||| ||... ..|..||||| .. ||.|..... ..|| |. || |.|.|
eanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
-TYGGVTVT--LHQSEVFAG--YENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAgPVIVHCSVGVERTGAYIVIDAML
.| .| . | || ... | | ... | . . . |||. |. | .. . . |. .||.. |. |||| || || ... ||
vkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkek.picvhcsagvgrtatfvgidyat
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
. . ... . . .| | . ||.. |. |.. ..| .
irimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 442-622 | 8.7e-28 | 91.8 | In-house | 24-208 (290) | alignment | ||
Range on Protein: 442-622
Range on HMM: 24-208/290.0
KSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAdeesDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD
.. ..|.| .||. |. . .|..|.... ||||| ...... . .| || || .||. ||.|| . . ..||||.. .. .|||
treaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPq
HG---ATKYG--HIGISVLSKQKKGDVICVKPKVTR--KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNV-PVLVQC
. . .. .. . ..|...| . . ... ..|.|. | |...|.| .|. . |..| .|. | .| |... |
geeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihc
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 447-623 | 5.8e-27 | 89.2 | In-house | 45-220 (439) | alignment | ||
Range on Protein: 447-623
Range on HMM: 45-220/439.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVApesseYWPDHGATK
. . |||. |. |.. ||.|.. | |||| ... . . .|||| | ||..||||.| . ||||| || . ||| . .
qeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevc
YGHIGISVLSKQKKGDVICVKPKVT----RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
|| | . | . . . . || . .| . | ..|...| || .| . |||.| ....... ||.|.|
ygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcs
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 158-409 | 6.4e-27 | 89.1 | In-house | 50-298 (301) | alignment | ||
Range on Protein: 158-409
Range on HMM: 50-298/301.0
NKNKNRYANIvAYDHSRVVLERVNGDEdlDYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET---
.|.|.|| .. . | | |.| | | .| | |. |||.||||. . | || |. . . ||||.. | ...||..| | |..
pkdkhryptv.PckPstavevivdGkr..vPihanwipts.GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekld
YGGVTVTLHQSEVFAGYENCTFILS---KEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRalnpRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
| .......|. . | .. .| | . .. |.|.|||. . . . |. . |..|||| |. |. |.| . . .
igrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvk....ksekPivvhcsaGiGrsvafigteylarev
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCgNTEIQSEKYNQAMQK
. .|... . | .|.|| . |||..| .. . | . ... |.. ..
eadptieltealkhlrehrwngvqtnsqlywmtlGtvyrlik.eygfdmkiyeeqlam
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 440-622 | 1.3e-26 | 88.0 | In-house | 30-233 (301) | alignment | ||
Range on Protein: 440-622
Range on HMM: 30-233/301.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHA--DEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSE
.. .|| . .| . ||| .| .. |..|..... . .|||| .... . ...|||.| |. .|. ||||.. .. .|||. ||... .. .
ksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceq
YWPDHGATKYGHIGISVLSKQKK--G-----------------DVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPV
|||. |... ..|. .... | | ||...|....| |. ..| . . . | || .|.| ||. | ||
ywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpv
LVQC
.| |
vVHC
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 438-622 | 1.4e-26 | 87.8 | In-house | 33-176 (392) | alignment | ||
Range on Protein: 438-622
Range on HMM: 33-176/392.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVapesse
.. ...|..|. ||.|||. .|. ..| ||.| .|||.|| .... .|.||.| | ...|||||| . .. ||.|...|..
diypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd......
ywpdhgatkyghigisvlskqkkgdvicvkpkvtRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNvPVLVQC
. .... | | . | || .|| . |.| .. ||.. | |....|
..................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqyth.pliihc
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 405-622 | 2.3e-26 | 87.1 | In-house | 12-223 (290) | alignment | ||
Range on Protein: 405-622
Range on HMM: 12-223/290.0
QAMQKLASVNGKFPMTGYALEFqrLNSVTSR-EIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKehaDEESDYINAVFLHAHrgRNAFIATQHPLL
.|..|.|| | . ..| |. |. . |... .| ...|||. |.. . ||.|. . ||. | ... . || || .|
eafekfasdvvkknvdelakey..leklkpylpvqylerkifdkntefkknrykdvvcndktrvilkd...GydGdyvhanyvkGl..kamfiltqGalk
ETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--ATKYGHIGISVLSKQKKGDVICVKPK-VTRK--KKTHEVRHLHHVSWTDKCIPKVSRS
.|| |.|||| . .. .|||| .| .. . ..|.|.. . .|.| . ...| . | | | | | | ..||. .|| ||.... . .
dtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstla
VLDLLDEVQTSqqqCGnvPVLVQC
.| .| ... | || | |
llrtlrilrka...sG..pvvvhc
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 441-612 | 2.9e-26 | 87.2 | In-house | 40-218 (300) | alignment | ||
Range on Protein: 441-612
Range on HMM: 40-218/300.0
EKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADeESDYINAVFLHAHRG--RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
. |... |.| .|||| |.. . .|| | . . ...|||| ... | . .|..| || ||.|||.|| . .. |||| . ... | .|
llstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfky
WPDH----GATKYGHIGISVLSKQKKGDVICVKPKV--TRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ
.|.. ..|. .. ... . || . |. |. .| || .. |.|. .|. .. |. |.||| ...
fPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 425-622 | 9e-26 | 85.7 | In-house | 16-209 (273) | alignment | ||
Range on Protein: 425-622
Range on HMM: 16-209/273.0
EFQRLNSVTsreiPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAdeesdYINAVFLHAHRGRNAF--IATQHPLLETVEDFWRMVTDYDIGTIV
||. |. . |... .||.| .| .|||. ... . || | .| . |||| ..... | . . ||.| || |||.|||.|| . . |.
efkelrelk....pldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevia
MLNNLHDQVAPESSEYWPDHGATK---YGHIGISVLSKQKKGDVICVKPKV--TRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcGNVP
|. . .. |||.. | .. . ...| ||. . . .| .. ....|| ||. |.| | .|. . ..| .. ||.. |. . |
mvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagP
VLVQC
..| |
ivvhc
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 436-598 | 2.4e-24 | 80.7 | In-house | 19-185 (297) | alignment | ||
Range on Protein: 436-598
Range on HMM: 19-185/297.0
EIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHadEESDYINAVFLH--AHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAP
| |. |. .. |.|||. ||.| .. || | . |.||||| .. .| .| || .||.|||..|.. |...|||. .| ..
eargesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrd
ESSEYWPD--HGATKYGHIGISVLSKQKK--GDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRS
|||. . | |.. . ||. || . .. .... ||| ..|| |. .|
kcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdled
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 450-624 | 3e-24 | 81.0 | In-house | 1-118 (182) | alignment | ||
Range on Protein: 450-624
Range on HMM: 1-118/182.0
NLHKNRFSDIIALNSCRvmlhkehadeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNnlhdqvapeSSEYWPDHGatkygh
||.|||.|||. . | .||||| .. . . |||||.|||.||.||.||. ...|.|||.|. . |||..
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell......
igisvlskqkkgdvicvkpkvtrkkkTHEVRHLHHVSWTDKCIPKvSRSVLDLLDEVQTsqqqcGNVPVLVQCRY
.... ......| | ..| ...||...||. . |||| |..
..........................erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsa
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 276-388 | 2.2e-23 | 77.9 | In-house | 34-140 (145) | alignment | ||
Range on Protein: 276-388
Range on HMM: 34-140/145.0
FILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDaGPVIVHCSVGVERTGAYIVIDAMLEqakksRTVDIRNYLIAIRKHRPHMVQ
. |. |.. .| . |.... ||| |||. . .|.| . .... ... |||.|||| || |||...... ||. . |.. . | .|..||..|.
lnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavp
TKEQYSFIHSAVL
. .|. |.. ..|
npgqlrflyefel
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 446-622 | 3.4e-23 | 76.9 | In-house | 34-217 (287) | alignment | ||
Range on Protein: 446-622
Range on HMM: 34-217/287.0
EKPQNLHKNRFSDIIALNSCRVMLHKEhADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD-HGA
|. . .|||..|.. .. ||.| .| .. |||||| .. ... .||||.| |. || ||||.| . ..... .. . .|||. .
eelaavkknryadvlPiddtrvllsae.gelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevP
TKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE---VRHLHHVSWTDKCIPKV----SRSVLDLLDEVQTSQQQCGNVPVLVQC
. | . .|....| .|. . .|.| |. |. .|| || .. | ||| . .. ... . |..| .
mrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhd
|
|||||||||
subfamily_egg_pd | Subfamily egg | 156-388 | 4.5e-23 | 76.4 | In-house | 38-267 (307) | alignment | ||
Range on Protein: 156-388
Range on HMM: 38-267/307.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLnkTKCHKYWPDKtETY
. |..| | . | ||| || .| |.| | ..| || .| || . . |||||.... | ||||| . .|. ||| |.
dnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkp.llnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpka.esd
GGVT--VTLHqSEVFAGYE--NCTFILSKEKRSGSRiVRQFHFTVWpdKGVPQYATAVLAFRRKVRALNpRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| .|. | . .. . | ..| | |. . . | .| .... | | .| | . . ||.|.. || .... . |. | .
slvtvpGslr.ienlkvdskadplfrvtklklvGgd.deerflehw..qgdvnnssdvysplrvlrklr.nlskpvvvqdilGvskaatlvaieiallsl
KKSRT--VDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVL
. . ... .|..|. |.. .| |.. ||
lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 449-622 | 5.6e-23 | 76.4 | In-house | 2-179 (237) | alignment | ||
Range on Protein: 449-622
Range on HMM: 2-179/237.0
QNLHKNRFSDIIALNSCRVMLHKEHADeeSDYINAVFLHAHRGR-NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG-ATK
.| |||...|.| . .||.|. .. |||||| .|. | . .||.| || . .|||.|| . |||| | .. .|||. .
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLH---HVSWTDKCIPKVSRSVLDLLDEVQT-SQQQCGNVPVLVQC
|| . .|. |.. | .... . .||| .| || |. .|. . ..| . .. |. | .. |
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihc
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 447-622 | 8.5e-23 | 75.8 | In-house | 5-181 (239) | alignment | ||
Range on Protein: 447-622
Range on HMM: 5-181/239.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGR-NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHgAT
| | |||...|.. . ||.| | | |||||| .|. . | .|.|||| . . |||||. . |||| | . . .|||| ..
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.ts
KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE--VRHLHHVSWTDKCIPKVSRSVLDLLDEVqTSQQQCGNVPVLVQC
|| . ... . | | ... .| | | . | | || .|. . .|| | .. | . | | ...|
kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihc
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 447-622 | 9.3e-23 | 75.6 | In-house | 4-180 (239) | alignment | ||
Range on Protein: 447-622
Range on HMM: 4-180/239.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGR-NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHgAT
| | |||...|.. . ||.| | | |||||| .|. . | .|.|||| . . |||||. . |||| | . . .|||| ..
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.ts
KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE--VRHLHHVSWTDKCIPKVSRSVLDLLDEVqTSQQQCGNVPVLVQC
|| . ... . | | ... .| | | . | | || .|. . .|| | .. | . | | ...|
kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihc
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 281-385 | 1.3e-22 | 75.5 | In-house | 41-139 (144) | alignment | ||
Range on Protein: 281-385
Range on HMM: 41-139/144.0
EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDaGPVIVHCSVGVERTGAYIVIDAMLeqakkSRTVDIRNYLIAIRKHRPHMVQTKEQY
|. . | . |.... ||| |||.... .|.| . .... ... |||.|||| || |||...... |. . ... . | .|..||..|.. .|.
epefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpgql
SFIHS
|..
rfLle
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 449-623 | 2.6e-22 | 74.2 | In-house | 42-212 (288) | alignment | ||
Range on Protein: 449-623
Range on HMM: 42-212/288.0
QNLHKNRFSDIIALNSCRVMLHkehaDEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--ATK
.| ..|. .. . .|| |. |. ||.| . ... .. .| .| || |.| .|.|. . |. ||||..| .. ..| ||.| . ...
anptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
YGHIGISVLSKQKKGDVICV--KPKVTRKKKTHE-VRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcgnvPVLVQCR
.|.. | |.. | . . ..... ... |..|| | |...|. | | ||. ... |. |..|...
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk.....Pivvhss
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 444-623 | 4.2e-22 | 74.7 | In-house | 40-220 (314) | alignment | ||
Range on Protein: 444-623
Range on HMM: 40-220/314.0
VGEKPQNLHKNRFSDIIALNsCRVMLHKEHADEeSDYINAVFLHAHrgrNAFIATQHPLLETVEDF----------WRMV--TDYDIGTIVM--------
|. .. | .|||. ||. . .||.|.... . |||||| ... . ..|||||.|| .||.|| |||| |... .|||
vadlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlad
-------------LNNLHDQVapesseywpdhgaT---------KYghigisvlskqkkgdvicvkpKVT--RKKKTHEVRHLHHVSWTDKCIPkVSRSV
|..| . ... ... .... ..... ..| . | .. .
elsrLdaAlgKtpllildgng.............neptaadlellk.....................eelydpelferlgikylripvpDgsap.lledf
LDLLDEVQTSqqqCGNVPVLVQCR
...|. ... . |||| |.
deflefieea...dkggpvlvHCk
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 401-565 | 5.3e-22 | 72.8 | In-house | 8-167 (310) | alignment | ||
Range on Protein: 401-565
Range on HMM: 8-167/310.0
EKYNQAMQKLASVNGKFPMTGYALEFQRLNSVTSREIPVEEksvgeKPQNLHKNRFSDIIALNSCRVMLHKEHADeESDYINAVFLHAHRGRNAFIATQH
|| .|.... |. . | . ....|.. . | ...||||.||.. |...|| |. ... ||| | .... |..|| .|
lkylkalenfiiateklgieglvkqyrkldakqdssltyea.....ykkymhknrysdvvcldtsrvklkidksr.yedyihanyvktnylrstficsqg
PLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATK-YGHIGISVLSKQKKGDVIC
|| |. |||||. . .|..| . .. | . ||| | |. || | .. ||. . ||
plqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeic
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 475-623 | 6.7e-22 | 73.4 | In-house | 2-108 (172) | alignment | ||
Range on Protein: 475-623
Range on HMM: 2-108/172.0
DEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLhdqvapesseywpdhgatkyghigisvlskqkkgdvicvkpKVTRKK
|| |||||| .|. .. . ||||| || .|..|||||. ...|..||.|..| .....
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.........................................lydpel
KTHEVRHLHHVSWTDKCIPkVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
.... ......| | . | .. .|..|. ... .... . |||| |.
lerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCs
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 439-622 | 1.2e-21 | 72.0 | In-house | 36-236 (418) | alignment | ||
Range on Protein: 439-622
Range on HMM: 36-236/418.0
VEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRnAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
| | |.| .| |||...|. .| || |.| . | |||||| .. . ||.|| || .|. |||||| . ||||. ... . |
psetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpntiadfwrmvwenrcriivmlsresencrikcdry
WPDH-GAT----------KYGHIGISVL--SKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC-----GNVPVLV
||.. | .| . .. .. . ..| . ..| . .|... . .. | |. || .. . .|| . |.| |||..|
wpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiiv
QC
.|
hc
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 478-624 | 2.2e-21 | 71.8 | In-house | 2-113 (174) | alignment | ||
Range on Protein: 478-624
Range on HMM: 2-113/174.0
SDYINAVFLHAHRGRNAFIATQHPLLetvedFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDhgatkyghigisvlskqkkgdvicvkpkvTRKKKTH
|||||| .|. .. . .||.|.|| ||.|. ...| |.|||.... |||. .|. ..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.............................lredler
EVRHLHHVSWTDKCIPKVSRsVLDLLDEVQTSQQQCGNVPVLVQCRY
.. ..... | | . | .| .|.....|.. ...... |||| |.
lgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsa
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 478-623 | 5.1e-21 | 71.0 | In-house | 4-158 (272) | alignment | ||
Range on Protein: 478-623
Range on HMM: 4-158/272.0
SDYINAVFLHAHRG---RNAFIATQHPLLETVEDFWRMvTDYDIGTIVMLNNLHDQVAPESSEYWP------------DHGATKYGHIGISVLSKQKKGD
|.|||| .. . .........|| |..||||. ...| |||.| ... . . . ||| .. ||.. . .||.. . |
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
VICVKPKVT---RKKKTHEVRHLHHVSWTDKCIPKvsRSVLDLLDEVQTsqqqcgNVPVLVQCR
.|. . .| ....||.|||. .| | ..|. ..|.||..... . |||| |.
yilrellltlllsagearevmhlhytdwpdhgvpq..eallellellld......ggpvlvHCs
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 159-277 | 1.1e-20 | 68.6 | In-house | 48-178 (350) | alignment | ||
Range on Protein: 159-277
Range on HMM: 48-178/350.0
KNKNRYANIVAYDHSRVVLER--------VNGDEDLDYINASFIHGY----DGTPRS-FIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCH
|||| ||. |.|||| |.. . |||||.... . | .|| |.||| ... |.... . . . |..||..| || ||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
KYWPDKteTYGGVTVTLHQ-SEVFAGYENCTFI
.||.. .| ..|| | . | .| ....
rYWqeg..sydditvklaskwenimgindssly
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 156-388 | 2.1e-20 | 67.3 | In-house | 49-282 (302) | alignment | ||
Range on Protein: 156-388
Range on HMM: 49-282/302.0
NKNKNKNRYANIVAYDHSRVVLERvngdEDLDYINASFIHGYDGTpRSFIASQGPLPP---AFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDKT
|| .||. .. ..|. .| || | .|.||| .. . | || | .| | . | |||||.... .|.|.| |.| ....| |.
kknlkknqsedvpildsnlvklea....epdsyvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks
ET---YGGVTVTLHQSEVFAGYE-NCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAML
.. || . | . | . . . . . | | | .. ..| |..| ||. ... . || |.. .... |. | || .. . .
gdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavav
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVL
|. .|. . | . ...||. ||..|.. .|| ... |.|
eklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 202-384 | 4.7e-20 | 66.6 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 202-384
Range on HMM: 5-197/199.0
RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKR--SGSRIVRQFHFTV
| .||.| || .. ||.|||| | |||. . ... ||| | || ..|| . . . | ...||... .| . .. ||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYAT---AVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT--VDIRNYLIAIRKHRPHMVQTKEQYSFIH
| .| |. | |.| | . . ||||||| | || .. .| . ..|.| ||. . .|. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 425-623 | 4.7e-20 | 66.7 | In-house | 11-200 (267) | alignment | ||
Range on Protein: 425-623
Range on HMM: 11-200/267.0
EFQRLNSVTSREIPVeEKSVGEKPQnlHKNRFSDIIALNSCRVMLHKEHADeesdYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||. .. ... . . .|..|| | .||. | . . ||.| .. . |||| ...... .||||.|| || |. ||. ...|... .||.|
efelikkisdtssti.sqsiaeknq..ernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivll
NNLHdqvAPESSEYWPDH--GATKYGHIGISVLSKQKKG--DVICVKPKVtRKKKTHEVRHLHHVSWTDKCIPKVsrSVLDLLDEVQTSQQQCGNVPVLV
. . .|| . | || . . .... ..| .. |. ... .|.| .. | . | . |. . | . || |..|
tkvf...tdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkf.knesahnvtlyyykkwnintnnkp..ylkplfgilaknqlengnrPlvv
QCR
.|
acs
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 202-384 | 5e-20 | 66.5 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 202-384
Range on HMM: 4-196/198.0
RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKR--SGSRIVRQFHFTV
| .||.| || .. ||.|||| | |||. . ... ||| | || ..|| . . . | ...||... .| . .. ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYAT---AVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT--VDIRNYLIAIRKHRPHMVQTKEQYSFIH
| .| |. | |.| | . . ||||||| | || .. .| . ..|.| ||. . .|. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 426-622 | 4.8e-19 | 63.5 | In-house | 22-216 (307) | alignment | ||
Range on Protein: 426-622
Range on HMM: 22-216/307.0
FQRLNSVTSREIPVEEKSvgekpQNLHKNRFSDIIALNSCRVMLHKEHAdeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLN
|. | | ..|| | | .|||..|. . . .|.... . . |||| | .| . ||..| || .|. .|| |. . .. ...||
frvlakktpegvtveafs.....antdknryqdvkcqdkgrivvkfdgl..asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlc
NLHDQVAPESSEYWPDHGATK--YGH----IGISVLSKQK---KGDVICV-KPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcgn
.. . .||| | .|. | .. | .| |.| | . || .|. ..|| | |. .|.. . ..||. |. .
kvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydtn....
vPVLVQC
||.| |
.pvvvhc
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 471-623 | 2.9e-18 | 61.7 | In-house | 5-117 (176) | alignment | ||
Range on Protein: 471-623
Range on HMM: 5-117/176.0
KEHADEESDYINAVFLHAHRgrnaFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDhgATKYGHigisvlskqkkgdvicvkpkv
. . |. .||||| .. .| .||||.|| .|..||..|. ...|...|.|..... |||. .|.|.
llgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi.....................
trkkkthevrHLHHVSWTDKCIPKVsRSVLDLLDEVQTSQQQcgNVPVLVQCR
. .|. | | ..| . .|.||..... ... . |||| |.
..........qylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCs
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 436-608 | 8.9e-18 | 58.9 | In-house | 23-198 (281) | alignment | ||
Range on Protein: 436-608
Range on HMM: 23-198/281.0
EIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHK-EHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPE
. | . .| ..| | .|||...| .|. || |. . .||| | .... . .| || | || |||||. . . .|||| .. . .
dppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrek
SSEYWPD--HGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT
.||.| | . .. .. .| . .. . ... . .|. . | | | .|. | .| .| ....
caeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 157-408 | 9.3e-18 | 59.4 | In-house | 18-277 (290) | alignment | ||
Range on Protein: 157-408
Range on HMM: 18-277/290.0
KNKNKNRYANIVAyDHSRVVLERVNGDEDLDYINASFIHGYDGTprSFIASQGPLPPA-------FEGFWRMVWEQNSQSIVMLTNLVGLNKT----KCH
|.. ..|... .. ..||||. ||| |... .| .|..| |. | || |. . .....||| . .. |
khemdqRlevpLv.eatrvvLkgygkrfnddyiHAnrvtcpngl..rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCa
KYWPDKTE---TYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIvRQFHFTVWPDKGVPQYATAVLAFRRKVRalnpRDAGPVIVHCSVGVERTGAYI
|| |.. . ...|.|| . | . |. . .. ... . . | . |.. .|. .||. |||||| |. | |
kYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftv.tHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAala
VIDAMLE-QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAV-LEALTCGNTEIQSEKYNQAMQ
|. |..| | ... | |.||.| ..........|. .. | | ... ...|. ..|..
aiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievldqfaeeetekkaka
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 435-546 | 1.3e-17 | 58.6 | In-house | 32-157 (350) | alignment | ||
Range on Protein: 435-546
Range on HMM: 32-157/350.0
REIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLH--------KEHADEESDYINAVFLHAH----RGRNAF--IATQHPLLETVEDFWRMVTDYDIGT
| | .. . | . |||...|. . || |. |.|. . .||||| .|. . | |||| || .||.||..... ..
sespsnDvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkv
IVMLNNLHDQVAPESSEYWPDHGATK
|..|... .. .||.. . .
ilsltsdvelnlekcyrYWqegsydd
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 214-391 | 1.4e-17 | 58.7 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 214-391
Range on HMM: 40-221/255.0
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTETYGGVTVTL--HQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYATA
. . |.... .... .|||... .. ||..|.| |. . |.|| ..| . | |.. |. . |. .... |..| |. |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkk..thtvkhysykGWieknaPelare
VLAFRRKVRalnprDAGPVIVHCSVGVERTGAYIVIDAM----LEQAKKSRTVDI--RNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
.| . || |. .|.|||| |. |. |..... . . . ... ||.. .. | .|..|. ..| | .| ||. .
ilnilkvvr.....dsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 447-611 | 1.7e-17 | 58.1 | In-house | 45-220 (305) | alignment | ||
Range on Protein: 447-611
Range on HMM: 45-220/305.0
KPQNLHKNRFSDIIALNSCRVMLHKEHAdeeSDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--A
. |. .|||. |. |. || |. .|| | .. . . || || || .| ||| | . . .| || || .. | .||.. .
eaqeagknrykdvgcldnnrvklegpwp...heyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdv
TKYGHIGISVLSKQKKGDVIC----VKPKVTR--------KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQ
.. | . | . . | |||. .|.. | | | . | |. .| ..|.|| . ..|.
lefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskg
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 489-623 | 1.8e-17 | 58.2 | In-house | 1-143 (199) | alignment | ||
Range on Protein: 489-623
Range on HMM: 1-143/199.0
HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKYGHIGISVLSKQKKGDVI----CVKPKVTRKKKTHEVRHL
|.|. .||||||| ||. |||.|| . | |||.|. . . . ||| . |..||| . ... . | | . ..| | |. |
hkgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishy
HHVSWTDKCIPKVSRSVLDLL--DEVQTSQQQCGNVPVLVQCR
|| .| |.|. | .. || .| . ||.|.|
qftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcs
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 481-622 | 1.9e-17 | 58.0 | In-house | 78-221 (301) | alignment | ||
Range on Protein: 481-622
Range on HMM: 78-221/301.0
INAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATK--YGHIGISVLSKQK------KGDVICVKpKVTR
| | .. .. . ||||| || .| |||| |.. ||. .|||| . .. .|| | . . | | | . .|.. . . |. |.
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtleve.dstg
KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcgnvPVLVQC
| .|. | | ...|||. .|| . ||.. |. |.. |..|.|
kfatrtvthyqysewtdrgvPkshaelfdlmelvkksek.....Pivvhc
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 491-623 | 6.9e-17 | 56.3 | In-house | 2-142 (198) | alignment | ||
Range on Protein: 491-623
Range on HMM: 2-142/198.0
GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKYGHIGISVLSKQKKGDVI----CVKPKVTRKKKTHEVRHLHH
|. .||||||| ||. |||.|| . | |||.|. . . . ||| . |..||| . ... . | | . ..| | |. |
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
VSWTDKCIPKVSRSVLDLL--DEVQTSQQQCGNVPVLVQCR
|| .| |.|. | .. || .| . ||.|.|
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcs
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 451-609 | 8.1e-17 | 55.9 | In-house | 29-193 (319) | alignment | ||
Range on Protein: 451-609
Range on HMM: 29-193/319.0
LHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHR-GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH----GAT
|.|. ... | ||.|.. |... |..| .. .. .| .||.| .| .. ||||.| . .|| | .|... .||.| . .
kdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnts
KYGHIGISvLSKQKKGDVICVKPKVTRKKKTHEVRHLHHV--SWTDKCIPKVSRSVLDLLDEVQTS
||.| .. | ... .| . . .. . .| |.| | | . .| .... .| ||..|
lyGdilvt.lkgrevkdryaistlllkrvdkeesrelthywykwleaevPaeeaaliamllevrss
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 489-624 | 2.7e-16 | 55.1 | In-house | 5-98 (152) | alignment | ||
Range on Protein: 489-624
Range on HMM: 5-98/152.0
HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWpdhgatkyghigisvlskqkkgdvicvkpkvtrkkkthevrHLHHVSWT
.. ..|||||.|. .|..|||||. ...|.|||||..|.. . .|. . .|. |
yampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.........................................qylhlpwp
DKCIPKVSRSVLDLLDEVQTSqQQCGNVPVLVQCRY
| . |. | .|.||. .. .. . |||| |..
Dhgvpdlsqlllflllfiekl.aldkggpvlVHCsa
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 450-622 | 4.7e-16 | 53.3 | In-house | 55-228 (305) | alignment | ||
Range on Protein: 450-622
Range on HMM: 55-228/305.0
NLHKNRFSDIIALNSCRVMLHKEHadeESDYINAVFLHAHR-GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATK-Y
. |||..|. . . | |.| |||| | .. . . ||..| || .|...|| || . . |||| . . ..||| |
aitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
GHIGISV--LSKQK----KGDVICVKPKVTR-KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqqcgnVPVLVQC
. || | .| | .. ..| ... ||||. | |. .| . . |.|| .. |. ||..|.|
lksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk.....vpivvhc
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 214-404 | 1.2e-15 | 52.1 | In-house | 46-241 (263) | alignment | ||
Range on Protein: 214-404
Range on HMM: 46-241/263.0
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTETYGGVTV--TLHQSEVFAGYENCTFILSKeKRSgSRIVRQFHFTVWPDKGVPQYATA
. . |.... .... .|||.. .. || .|.| |. . |.| | ||.| .. . .|.. |. . |... .. |..| |. |
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.Kkk.thtvkhysykgWiekndpelare
VLAFRRKVRalnprDAGPVIVHCSVGVERTGAYIVIDA----MLEQAKKSRTVDI--RNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSE-
.| . .| . ...|||| |. |. |. |.. |. . ... ||.. .. | .|..|. ..| | .| ||. . ... . |
ilnilkvar.....nskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakgelea
KYN
||.
kyq
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 322-386 | 1.2e-15 | 52.0 | In-house | 245-310 (319) | alignment | ||
Range on Protein: 322-386
Range on HMM: 245-310/319.0
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKS-RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSA
. ||..|||| || ||| | | ... ..| |.||| . . .|. | . |.||||| ||.
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykv
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 314-391 | 1.6e-15 | 51.7 | In-house | 219-295 (297) | alignment | ||
Range on Protein: 314-391
Range on HMM: 219-295/297.0
RKVRALNPRDAgPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
.|| ||.| ...|||| || |.| . |..|.. .| | |.. | .|. |. .||| ||. ....|||. |
eslraemprna.yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 328-394 | 2e-15 | 50.9 | In-house | 2-68 (69) | alignment | ||
Range on Protein: 328-394
Range on HMM: 2-68/69.0
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCG
.|||| | |||..| | . . | . ||| | . .|| || || . .| ||| |. ||| |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_egg_pd | Subfamily egg | 447-595 | 2.3e-15 | 51.1 | In-house | 37-187 (307) | alignment | ||
Range on Protein: 447-595
Range on HMM: 37-187/307.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQvaPESSEYWPDHG--A
. ||.| | . .|.|| |. .. |.| | .. . | || .| || .||.|||||| .. ||||. . . ||| .
sdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesds
TK--YGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKV
. | . | | ..| | . |. .| |.| | . . .|
lvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqgdvnnssdv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 113-198 | 2.8e-15 | 50.6 | In-house | 4-87 (440) | alignment | ||
Range on Protein: 113-198
Range on HMM: 4-87/440.0
KPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYD
.|| .| | .|| . . | |. . .| . | | | | | |||| ||.|||||||.|| |.| | ||||||.| | .
rpiivadfadyvqnnrrsrafedewsllpsglsqpsdiaslpnn..kvknryrnilaydhsrvmleevkgvpdsdyinasyingie
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 492-551 | 3.4e-15 | 50.3 | In-house | 235-292 (440) | alignment | ||
Range on Protein: 492-551
Range on HMM: 235-292/440.0
RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVapeSSEYWPDHG-ATKYGHIG
.||||||| || || ||||.| || | ||.|||.| |. | ||| . .| .
knafiatqmpldstvldfwrlvhdyristiimlnqlndkt...csiywpvntrsvtfgpft
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 328-394 | 3.9e-15 | 50.0 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 328-394
Range on HMM: 1-67/69.0
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCG
.|||| | |||..| | . . | . ||| | . .|| || || ...| ||| |. ||| |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 214-391 | 5.2e-15 | 49.7 | In-house | 103-288 (302) | alignment | ||
Range on Protein: 214-391
Range on HMM: 103-288/302.0
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTE---TYGGVTVT---LHQ-SEVFAGYENC-----TFILSKEKRSGSRIVRQFHFTVWPDKG
. | .| .. . | .| |...| .. || .|. || . ..| ||. ... | |. .. . .| |. . | ..|. |||.|
tlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsawpdhG
VPQYATAVLAFRRKVRALNPRdagpVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
|. | . | . . |.||||.|| |||. . | .. .| .. |. . .. .|. | ||...| .. | .|
apkeaytaldilkfcesykkn....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkgl
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 152-391 | 1.2e-14 | 48.6 | In-house | 41-279 (303) | alignment | ||
Range on Protein: 152-391
Range on HMM: 41-279/303.0
RKPANKNKNKNRYANIVAYDHSRVVLErvngdeDLDYINASFIHgYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK
.. || .|||..... |||.| | | || ||... | . . | .| ||. . ||.|. ||. . ...| .| . .| .
knqfvknmdknrfvdvicldhskvkls......dssyihasyle.ld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn
TETYG----GVT-VTLHQSEVFAGYENCtfILSKEKRSGSRIVRQFHFTVWPDKGVPQY-----ATAVLAFRRKVRALNprDAGPVIVHCSVGVERTGAY
. . ... |. |. .|| . . .. |. || . .| . . .| |. | . |. |.|..
qdflkfeersirvgefkrvelgdgwvlk..vlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkys..dstptvymslsgcgragtf
IVID-AMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
... | | .. ..|. . | .|. | | || |.|.... . | .
alfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_eak_pd | Subfamily eak | 158-316 | 2.4e-14 | 47.5 | In-house | 52-207 (332) | alignment | ||
Range on Protein: 158-316
Range on HMM: 52-207/332.0
NKNKNrYANIVAYDHSRVVLERVNGDeDLDYINASFIHgYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT---ET
. |.| .|| ||. | | . | ||||| . . | .| . . ||.|| ||.| .||.| . | |. | ||.||||
avnrn.vvkivpydrylvrltssqln.rlGyinaslae.fsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelk
YGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYAtAVLAFRRKV
.| . |. . . .| ..||| . | ... | . .|.| ||.|. .
fGildverkefvkrniletrllelskGne..thrvlhykvfGwtettlpkye.dflalrkvm
|
|||||||||
subfamily_eak_pd | Subfamily eak | 435-596 | 3.2e-14 | 47.1 | In-house | 37-198 (332) | alignment | ||
Range on Protein: 435-596
Range on HMM: 37-198/332.0
REIPVEEKSVGEKPQNLHKNrFSDIIALNSCRVMLHKEHADeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPE
. .. .|.... .....| .|. . | | . . |||| . . .| | . . | ||.|| . .||.| . .. .
dyqrllsisetarleavnrn.vvkivpydrylvrltssqln.rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelklek
SSEYWPDHG--ATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVS
| |.||.. |.|.. . . |.. . . .... .||.| | . ||. .||.
sdkyfpdktreelkfGildverkefvkrniletrllelskGnethrvlhykvfGwtettlpkye
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 478-624 | 1.1e-13 | 46.6 | In-house | 3-101 (151) | alignment | ||
Range on Protein: 478-624
Range on HMM: 3-101/151.0
SDYINAVFLHAHrgrnaFIATQHPlletVEDFWRMVTDYDIGTIVMLNNLHDQVapESSEYWPDHGatkyghigisvlskqkkgdvicvkpkvtrkkktH
|||||. .. . ......| .||.... ...| |||.|.... ||.|..| .
sdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................i
EVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTsqqqCGNVPVLVQCRY
||.|.. ..|.| .| .||..|.... ..| |||| |.
evlhipildwpdpglplsfdavleflellld....kkngpvlvHCsa
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 450-622 | 1.4e-13 | 45.4 | In-house | 35-210 (285) | alignment | ||
Range on Protein: 450-622
Range on HMM: 35-210/285.0
NLHKNRFSDIIALNSCRVMLhKEHadeESDYINAVFLHA-HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--ATK
| ||..|. ... ||.| |.| . ||| | ... . ....|.|| || ||. |||.|. . | ..|| | . . . |.|.. |
npdlnryadvrcieetrvvl.knh...drdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvk
YGHIGISVLSKQKK---GDVICVKPKVTRKKKTHEVRHLHHV---SWTDKCIPKVSRSVLDLLDEVQTSQQQcgNVPVLVQC
.|. |.. ... | .. . . . | .. || | |. |. .| ...| |. . . . |. |.|
fgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhc
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 464-623 | 4.5e-13 | 44.7 | In-house | 4-118 (178) | alignment | ||
Range on Protein: 464-623
Range on HMM: 4-118/178.0
SCRVMLHKEHADEESDYINAVFLHAHrgrnaFIATQHPLletvEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGAtkyghigisvlskqkkgdv
.|| |.. | ||||||.. . ......| .|..... ...|..||.|.. ... .|||.
rtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag...................
icvkpkvtrkkkthevRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNvPVLVQCR
. .|. . | . | ... .|.... ... ....|. |||| |.
................iqylhipipDhgvpdllehflefvefieealdekgg.pvlVHCs
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 446-547 | 8e-13 | 42.6 | In-house | 92-186 (244) | alignment | ||
Range on Protein: 446-547
Range on HMM: 92-186/244.0
EKPQNLHKNRFSDIIALNSCRVMLHKEHAdeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHdqvapESSEYWPDHGAT
.|.| .||| . . .. || | | |||| |. .| ||||| .| |||.|. . . .|.| . | |||||
fnpnnswknregaglpfdfnrvplskgsm..gntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsve.....eedeywpdsepl
KY
..
ew
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 159-277 | 2e-12 | 41.1 | In-house | 49-181 (349) | alignment | ||
Range on Protein: 159-277
Range on HMM: 49-181/349.0
KNKNRYANIVAYDHSRVVLERVN--------------GDEDLDYINASFIHGYDGTP-RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTK
|||| .|. |.||||.|.. . ||||| ... .. . .|| | ||| . . |.... .. . .. |.. |. |
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CHKYWPDktETYGGVTVTLHQSE-VFAGYENCTFI
|..|| . .| ..|| | | |. . ..
cdiywqe..lsysnitvklqnsslyianvqGnslr
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 497-611 | 3.7e-12 | 40.9 | In-house | 39-150 (255) | alignment | ||
Range on Protein: 497-611
Range on HMM: 39-150/255.0
AtqhplleTVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVIC----VKPKVTRKKKTHEVRHLHHVSWTDKCI
||. |.... . ..||| ..... . |.|.| | ..| . . ||. . ....|||||.|.| .. | .|
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWiekna
PKVSRSVLDLLDEVQTSQQ
|. .| .| .| |. |.
Pelareilnilkvvrdsks
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 113-209 | 1.9e-11 | 38.0 | In-house | 3-95 (95) | alignment | ||
Range on Protein: 113-209
Range on HMM: 3-95/95.0
KPIPIALFPEYVAKMHGGI--RLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLErvnGDEDLDYINASFIHGYDGTpRSFIASQG
||| ...| .| .|| .. |.| . |. . || |||. ||. || .|||| | ||||| |. || .||.||
kpihvsvfhshvlemhsnsdqefdnefksismtsgapytvgssean..ipknrflnifpydatrvvlt...tkrdsdyinacfvdgyark.ncyiaaqg
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 497-610 | 2.7e-11 | 37.9 | In-house | 42-155 (263) | alignment | ||
Range on Protein: 497-610
Range on HMM: 42-155/263.0
AtqhpLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTR----KKKTHEVRHLHHVSWTDKCI
|..|.. |.... ..||| . ... . |.|.| | ..| . . . ||. ... |||||.|.| .. | .|
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWieknd
PKVSRSVLDLLDEVQTSQ
|. .|..| .|. .. |.
pelareilnilkvarnsk
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 446-524 | 2.8e-11 | 37.5 | In-house | 33-116 (347) | alignment | ||
Range on Protein: 446-524
Range on HMM: 33-116/347.0
EKPQNLHKNRFSDIIALNSCRVMLHKEH-----ADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
| ..| ||| | .. ||.| |. ||. |||| .. .. .| ||.|| .|| |||.||. . .| .
ewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 449-524 | 4.1e-11 | 37.0 | In-house | 46-114 (303) | alignment | ||
Range on Protein: 449-524
Range on HMM: 46-114/303.0
QNLHKNRFSDIIALNSCRVMLHkehadeESDYINAVFLHAHRGRNAfIATQHPLLETVEDFWRMVTDYDIGTIVML
.|..|||| |.| |. .| | .| || | .|. . ..| | || || | |||.|. . . ...|
knmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlll
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 462-622 | 6e-11 | 37.0 | In-house | 30-198 (290) | alignment | ||
Range on Protein: 462-622
Range on HMM: 30-198/290.0
LNSCRVMLHKEHADEESDYINAVFLHAHRGRnAFIATQHPLLET-------VEDFWRMVTDYDIGTIVMLNNLHDQVAPE----SSEYWPDHGA--TKYG
.. ||.|. .||| | .. | ..|.|| |. .. .|.|| |. . . .||| . ... | ..| |.. |..
veatrvvLkgygkrfnddyiHAnrvtcpngl.rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk
HIGISVLSKQKKGDVICVKPKVT-RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqqcgnVPVLVQC
. .. || |. ||. . |. ... . | | ..|.. ... ....|.|.. |..|. ||.| |
gltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvkask.....tpvivHc
|
|||||||||
subfamily_eak_pd | Subfamily eak | 324-402 | 6.6e-11 | 36.2 | In-house | 237-317 (332) | alignment | ||
Range on Protein: 324-402
Range on HMM: 237-317/332.0
AGPvIVHCSVGVERTGAYIVIDAMLE--QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQS-EK
| |. .. | |.|...||| ... ..|| . . .... ....| | | .. |.|||. .||. | | ... .|
fap.iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnrlrdlkk
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 322-388 | 1.5e-10 | 35.4 | In-house | 260-341 (350) | alignment | ||
Range on Protein: 322-388
Range on HMM: 260-341/350.0
RDAGPVIVHCSVGVERTGAYIVIDAMLE-------QAKKSRTVDIRNY--------LIAIRKHRPHMVQTKEQYSFIHSAVL
. |..|||| || ||| .. .| .|. |.|| .| . . .|| | |||...|. ||. |.|
arsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 157-254 | 3.4e-10 | 33.1 | In-house | 26-90 (169) | alignment | ||
Range on Protein: 157-254
Range on HMM: 26-90/169.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINAsfihgydgtprsfiasqgplppafegfwRMVWEQNSQSIVMLTNLVGLNktkchKYWPDKTET
|. ||| | .| | || |.|| | ||||| ||.|| |. ||.| . | .||.| .
cnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlgdtddkn.....nfwpekedy
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 157-302 | 4e-10 | 33.7 | In-house | 95-235 (244) | alignment | ||
Range on Protein: 157-302
Range on HMM: 95-235/244.0
KNKNKNRYANIVAYDHSRVVLERvnGDEDLDYINASFIhGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLvglnkTKCHKYWPDKT--ET
.| ||| . . .| .|| | . | ||||||. | | .| .| || . ||.|. |. . .|.| . . .|||| |
nnswknregaglpfdfnrvplsk..gsmgntyinasfv.gclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsv.....eeedeywpdseplew
YG-GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGV
| .|||| . . | . . . . . | . || |
yeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 157-254 | 4.1e-10 | 32.7 | In-house | 25-89 (169) | alignment | ||
Range on Protein: 157-254
Range on HMM: 25-89/169.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINAsfihgydgtprsfiasqgplppafegfwRMVWEQNSQSIVMLTNLVGLNktkchKYWPDKTET
|. ||| | .| | || |.|| | ||||| ||.|| |. ||.| . | .||.| .
cnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlGdtddkn.....nfwpekedy
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 438-542 | 2.3e-09 | 31.0 | In-house | 36-156 (349) | alignment | ||
Range on Protein: 438-542
Range on HMM: 36-156/349.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKE--------HADEE------SDYINAVFLHAHRG--RNAFIATQHPLLETVEDFWRMVTDYDIGTI
.... . | . |||..||. . ||.|.| .. | ||||| .|. | . .|||| || ||.||..... . .
eiddvilseGvelfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklv
VMLNNLHDQVAPESSEYWPDH
. ||. ... || .
lsLnddkelslekcdiywqel
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 155-231 | 2.8e-09 | 31.0 | In-house | 34-114 (347) | alignment | ||
Range on Protein: 155-231
Range on HMM: 34-114/347.0
ANKNKNKNRYANIVAYDHSRVVLERV-----NGDEDLDYINASFIHgYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
.|. .||| . | .|||| . |. ||||| |. .| . . .| .| ||| . ||.|| . .|
wekslsknrskdvklidatrvvlspeksknsraddvetyinashik.fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 477-558 | 4.3e-09 | 30.8 | In-house | 12-88 (130) | alignment | ||
Range on Protein: 477-558
Range on HMM: 12-88/130.0
ESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHdqvapESSEYWPDHGATKYGHIGISVLSKQ
. .|||| |. . .. ||||| .| |||.|. . . .|.| . | ||||| .. | | . .
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsve.....eedeywpdsePlewyeediivtltd
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 157-236 | 3.4e-08 | 27.4 | In-house | 33-110 (332) | alignment | ||
Range on Protein: 157-236
Range on HMM: 33-110/332.0
KNKNKNRYANIVAYDHSRVVLERVNGDEdlDYINASFIHGYDGTpRSFIASQGPLPPAFEG-FWRMVWEQNSQSIVMLTNL
.| . || . ..||||| | .| . |. |||.. || ..| .| |. | ||||| |.. |... ..
nnmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskk.sayifaqapfndhteyvfwrmvserkpsmilvfgdi
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 240-394 | 4.2e-08 | 27.0 | In-house | 146-306 (332) | alignment | ||
Range on Protein: 240-394
Range on HMM: 146-306/332.0
NKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDK-GVPQYATAVLAFRR--KVRALN--PRDAGPVIVHCSVG
. |.|.||.|. ..... |. .. || |. .. . .|| | | .|.| . | . .|. . ||... |. |
kakicrkfwpekrskkdfpalsiqasddhsethmktfnltvtekkqdhqtvlmhfyewadasklpeymldmrasiklqyirsskktgvcigpimlvcatg
VERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE-ALTCG
||. . || .. . . . | ... . ||. .| ..| || ... |.| |
vekcaisatidiivsriteehrvgfketmsaikmqrfgcfrtvgpystacemlmkfavttg
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 443-499 | 5.7e-08 | 26.8 | In-house | 41-94 (95) | alignment | ||
Range on Protein: 443-499
Range on HMM: 41-94/95.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEhadEESDYINAVFLHAHRGRNAFIATQ
.|| |. |||| .|. .. ||.| .||||||.|. . .|..||.|
tvgsseanipknrflnifpydatrvvlttk...rdsdyinacfvdgyarkncyiaaq
|
|||||||||
PTPc_DSPc_SM00012 | 579-623 | 7.1e-08 | 28.0 | In-house | 2-47 (105) | alignment | |||
Range on Protein: 579-623
Range on HMM: 2-47/105.0
VRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCG-NVPVLVQCR
|.|.|. .|.|...|. | |.|.||..|........ . ||.|.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCs
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 203-267 | 2.1e-07 | 24.6 | In-house | 237-300 (440) | alignment | ||
Range on Protein: 203-267
Range on HMM: 237-300/440.0
SFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNlvgLNKTKCHKYWPDKTE--TYGGVTVTLHQSEV
.|||.| || . |||.| . . .|.|| . || | ||| .| |.| || . ||
afiatqmpldstvldfwrlvhdyristiimlnq...lndktcsiywpvntrsvtfgpftvghkgsen
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 577-623 | 6.2e-07 | 23.1 | In-house | 89-135 (440) | alignment | ||
Range on Protein: 577-623
Range on HMM: 89-135/440.0
HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
. ... |. .| || .||.. || ....|. ||...|| |.||.|
rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcs
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 172-301 | 6.5e-07 | 23.7 | In-house | 7-125 (130) | alignment | ||
Range on Protein: 172-301
Range on HMM: 7-125/130.0
HSRVVlervngdeDLDYINASFIhGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLvglnkTKCHKYWPDKT--ETY-GGVTVTLHQSEVF
||. . .||||||. | | . .. .| || . ||.|. |. .|.| . . .|||| | | ..||| . . |
vsrlq........gntyinasfv.Gllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsv.....eeedeywpdsePlewyeediivtltdrdef
AGYENCTFILSKEKRSGSRIVRQFHFTVWPDKG
. . ... . . |. . || |
knikasnleiesdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 454-610 | 9.8e-07 | 22.8 | In-house | 47-209 (312) | alignment | ||
Range on Protein: 454-610
Range on HMM: 47-209/312.0
NRFSDIIALNSCRVMLhkehADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD---------HGA
||. .| . | | | .| || | |.. . |..|| || .|. ||... .|..| . .. . ....| | |
nrypniqcwdrgrftl....agdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrv
-TKY-GHIGISVLSKQKKGD-VICVKPKVTrkKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQ
|.| | | ||.| |. | | | . . | || |. .| . | || |. .
yteycteieiggkskdkithrvlkvvvkat..gqesklnhyqwaswpdhgmpdscdtalrllsavkkdk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 322-389 | 1.6e-06 | 21.7 | In-house | 263-342 (349) | alignment | ||
Range on Protein: 322-389
Range on HMM: 263-342/349.0
RDAGPVIVHCSVGVERTGAYIVIDAMLE----QAKKSRTVDIRN-------YLI-AIRKHRPHMVQTKEQYSFIHSAVLE
. ...|||| | ||| .. .| .|. ..| ..... . . .|| | ||| |. .|. |.|.
dqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 449-540 | 1.9e-06 | 21.5 | In-house | 50-139 (302) | alignment | ||
Range on Protein: 449-540
Range on HMM: 50-139/302.0
QNLHKNRFSDIIALNSCRVMLHKEhadeESDYINAVFLHAHRGRNAFIATQHPLLETV---EDFWRMVTDYDIGTIVMLNNLHDQVApESSEYWP
.||.||. |. .|.| .| |..| . .|.|| .. .. | .| | .... |.||||| . | ..|.| . ||..|
knlkknqsedvpildsnlvkleae....pdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfp
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 552-624 | 1.9e-06 | 23.2 | In-house | 22-92 (144) | alignment | ||
Range on Protein: 552-624
Range on HMM: 22-92/144.0
ISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcGNVPVLVQCRY
. | |.. . ||.. .. ..|. ...|..| | ..| . .|..|. ... .. . |||| |..
lellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsa
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 292-384 | 3.1e-06 | 21.7 | In-house | 85-169 (182) | alignment | ||
Range on Protein: 292-384
Range on HMM: 85-169/182.0
FHFTVWPDKGVPQYATAvLAFRrKVRALNPrDAGPVIVHCSVGVERTGAyiVIDAMLEQAKKsrtVDIRNYLIAIRKHRPHMVQTKEQYSFIH
.. |.| ||. .. | || | . | | ||| | ||| .| ..| ||. .. . . .|..||. .||.|| ...
vynfgwkDygvasleri.Ldiv.kvvafal.qegkvavhChaGlGrtGv..liacylvyakr...ltaekaiklvrskrpksiqtreqvelvk
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 293-385 | 5.9e-06 | 21.6 | In-house | 83-171 (194) | alignment | ||
Range on Protein: 293-385
Range on HMM: 83-171/194.0
HFTVWPDKG-VPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIdAMLEqakkSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHS
. .||.| ||.... .. . || | | ||| |. ||| .. .... .. . . . .| ||..... .... ...
lklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.YLiy....rlgmsaeeAialfrekRpgaipnqdyleallk
|