subfamily_Anemone-PTP-4_pd |
Subfamily Anemone-PTP-4 |
4-241 |
1.1e-138 |
455.1 |
In-house |
1-237 (237) |
alignment |
Range on Protein: 4-241
Range on HMM: 1-237/237.0
PENKIKNRYGNIVTYDHTRVVLKGPGGNrdgrSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQ
.||||||||||||.|||.||||||.|.. ||||||..|.|||||||||||||||.|.||||||||||||.||||||||||||| ..|||||||.|.|
senkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdq
PKPYGQYTVSLCKNEAFADYTVRTFLVTSA-PSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRH--NTAPWIVHCSAGVGRTGAFIVIDAML
|..||..||||.|.|.|.|||||..|.. .| |.|.||.||.|||.||||...|.|||||.|||.|.| ...|||.|||||||||| |.||||||
paaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidaml
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
||||||||||||||| . ||| ..||||||||||...||
rqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
subfamily_PTPRD_pd |
Subfamily PTPRD |
1-282 |
1.1e-130 |
431.9 |
In-house |
43-320 (564) |
alignment |
Range on Protein: 1-282
Range on HMM: 43-320/564.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGGNrdGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|.||.|| |||| ||| |||.||||. |. ||||||||..|.. ..|.|||.|||......|||.|||....|.||||| | | .|.|||||||.
ankpaNkaKNRyanivaYdhsRVvLskvegd..egsDYINAsfidgyr.krkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPe
TNqPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
.. .. ||..||.| ..| .|||..||| .. . |.|.| . |.||| |||.|||..||..|....|. . ..... |..|||||||||||.||||||||
kg.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividaml
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQRLS
...||.|.||||.||.| | .|. ||||..||.|||.|.|||| ||.|.... ||.. ..||..... ....|.| |||||.
erikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkLaeveedtemtgleleFqrLa
|
subfamily_Nvec-PTP-1_pd |
Subfamily Nvec-PTP-1 |
1-242 |
3.6e-111 |
365.0 |
In-house |
2-239 (239) |
alignment |
Range on Protein: 1-242
Range on HMM: 2-239/239.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
||| || |||| |||||||.||||. . | .|||||||.|. .||.|| |||.|| ||.|. |||.|.|||| ||||||||||| |.|||.||||
akkrvnkaknryanivtydhsrvvlekl..sndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
TNQpkPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
. | . |.| | | |||| .|||... |.|..||||||||||||||||||||| .|.|| ..| . ||..||||||||||||.||||||
sts..kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidaml
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
||||..| |||.|||.| | ||| |||| .|||||| |||||
rqakkqktvdifnyvkairedrphmvqtseqyvfihlavlea
|
subfamily_Anemone-PTP-1_pd |
Subfamily Anemone-PTP-1 |
1-241 |
1.5e-110 |
363.0 |
In-house |
3-239 (239) |
alignment |
Range on Protein: 1-241
Range on HMM: 3-239/239.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
||| || |||| |||||||.||||. . | .|||||||.|. .||.|| |||.|| ||.|. |||.|.|||| ||||||||||| |.|||.||||
akkrvnkaknryanivtydhsrvvlekl..sndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
TNQpkPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
. | . |.| | | |||| .|||... |.|..||||||||||||||||||||| .|.|| ..| . ||..||||||||||||.||||||
sts..kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidaml
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
||||..| |||.|||.| | ||| |||| .|||||| ||||
rqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
subfamily_Anemone-PTP-2_pd |
Subfamily Anemone-PTP-2 |
246-536 |
6.6e-105 |
345.6 |
In-house |
1-292 (298) |
alignment |
Range on Protein: 246-536
Range on HMM: 1-292/298.0
GSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQRLSIFWL-SPDVRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERN
|.|.|.|..|.. ..||..........||..|||||. .. | |.. | .|||..||..||| || |. ..|.| .|||||||.|||..||
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLe.kedadeesdYiNAsflhaykgrn
AFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHS
|||.|||||. |.. |||||...| ||||||..| | |. ....|||..|.|.|| |.|.|....... .|.|.. .. | ... ........|.|.|..
afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkg
VPDKPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLDS
|| . .| ||.....|||..|.|...||||.||||||| .|| ||.|||| |.||||||.|| ||..|||||.| |||.|.|...| .|||
vpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealds
|
subfamily_Anemone-PTP-2_pd |
Subfamily Anemone-PTP-2 |
1-251 |
2e-98 |
324.3 |
In-house |
51-298 (298) |
alignment |
Range on Protein: 1-251
Range on HMM: 51-298/298.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGgnRDGRSDYINASFLQGFDGTPkKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|.||||| |||| .|...|..||||. | |||||||||....|.. .||.|.|.... |||.||..| ..||||| | | | |.||||||
arkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhaykgrn.afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPd
TNqPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNT-APWIVHCSAGVGRTGAFIVIDAM
.. . ||. |||| ..| |||..||.. |... ....| . | |||.|||||||..||.|| ...|. ... .| ||.|||||||.|.||.||..
eg.ketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsv
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQ
| ..|...|||....|.. | .||..|||..|||||. |||||| .....|.
lervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndeie
|
subfamily_Nvec-PTP-2_pd |
Subfamily Nvec-PTP-2 |
1-247 |
2.1e-97 |
320.2 |
In-house |
4-245 (250) |
alignment |
Range on Protein: 1-247
Range on HMM: 4-245/250.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGgnRDGRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEkCHKYWPd
||||.|| |||| .|...|..||||. | |||||||||.|.|.. | .||.|||.... |||.||..| ..||||| | | |. .|.|||
akkpqnkeknryadiialdssrvvLekek..gdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywP.
TNQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRH-NTAPWIVHCSAGVGRTGAFIVIDAM
..... ||. |||| ..| |||||.|.. ...| ...| . |.||.||||||||..||||| ..||. . .. ..|| ||.|||||||.||||.|||.
vekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidav
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCgS
| ..|..||||....... | |||..|....||||.....|.||.. .
lerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds.v
|
subfamily_Anemone-PTP-6_pd |
Subfamily Anemone-PTP-6 |
3-281 |
2.3e-97 |
320.9 |
In-house |
43-318 (318) |
alignment |
Range on Protein: 3-281
Range on HMM: 43-318/318.0
KPENKIKNRYGNIVTYDHTRVVLKGPGGNRdgRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDtN
.| || |||| ||..|||||| |. |. ||||||....|. |.|||||.|. ..|||.|||. ..|||||| . | .|.|.|.|||. .
epvnkaknryanilaydhtrvkLqmlegee..gsDyinanyidGyr.rkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPs.k
QPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINES-RHNTAPWIVHCSAGVGRTGAFIVIDAMLR
... ||. .| | .. ..||..|.| || ..|.| . |||.| |||.|||. .. .| . ... . .... | .||||||||||| ||..|..|.
gsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdille
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQRL
..|. ..||....|. | |. ||||.|||.||. ..|||| .| |...| .||. . .|.. | . . |||||
rikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelreqdpesgttemdaefqrl
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
2-247 |
2.7e-94 |
311.3 |
In-house |
64-303 (308) |
alignment |
Range on Protein: 2-247
Range on HMM: 64-303/308.0
KKPENKIKNRYGNIVTYDHTRVVLkgpggnrDGRSDYINASFLQGFD-GTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
..|||| |||| .|. |||.||.| |. |||||||. .|.. . |.|.||.||| . ...|||.|||.....|||||| |.| ..|||..|||.
llpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwpl
T--NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESrhNTAPWIVHCSAGVGRTGAFIVIDA
. .... ||..|| | . | ..||||||. .| ..| |.....|.| ||| |||......|.| ... . . | .|||||||||||.||..|
elgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdl
MLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGS
.|.| .... ||....|. | ||.||||..||.|..||.|| | .
lleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
subfamily_Anemone-PTP-5_pd |
Subfamily Anemone-PTP-5 |
1-279 |
3.2e-93 |
307.3 |
In-house |
43-319 (319) |
alignment |
Range on Protein: 1-279
Range on HMM: 43-319/319.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgrSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|.|.||| |||| ||..||.|||||. | . ||||||||..|.. .|.||.|.|.| .|||.|||.|..|..||||.| | | |..||||.
askeenkkknryqnilaydrtrvvlseldgveg..sdyinasfidgyqer.ekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpe
TNqPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSN-EQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESR-HNTAPWIVHCSAGVGRTGAFIVIDA
.| .. ||...| | ..| .|| .| . . . |. | | . ....| |||..||..||..| . |.| . . .. | .|||||||||||.|||.||
en.feeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivlda
MLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQ
|| . || |.|....|. .| |. |||...|| ||. |.|||. .|.|.|. .||. . .|.. . .| | |||
mlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqlaekvadtgetglerefq
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
2-243 |
1.2e-92 |
305.7 |
In-house |
45-286 (288) |
alignment |
Range on Protein: 2-243
Range on HMM: 45-286/288.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGnrDGRSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDt
..|||. |||| .|. |||.||.|. ..| .. |||||||...|.. . | .||.||| . ...|||.|||.....||||||.|.| ..|||..|||.
llpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.
NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSA----PSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVID
.... ||..|| | . | ..||||||. || ...| |.....|.| ||| |||......|.| ..... ... | .|||||||||||.||..|
ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfiald
AMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
.|.| .....||....|. | ||.|||| .||.|...|.||.|
llleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
2-248 |
2.6e-92 |
304.5 |
In-house |
24-279 (284) |
alignment |
Range on Protein: 2-248
Range on HMM: 24-279/284.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNrDGRSDYINASFLQGFD----GTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKY
..|||. |||| .|. |||.||.|| ..|. .. |||||||...|.| ..||.||.|||.. ...|||.|||.....||||||.|.| ..|||..|
llpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqY
WPDTNQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAP-SNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESR--HNTAPWIVHCSAGVGRTGAFI
||...... ||..|| | . | . ||||||. .| ..| |.....|.| ||| |||.... .|.| ... . . .. | .|||||||||||.||
wplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfi
VIDAMLRQAKEKK---VVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGST
..| .|.| .... .||....|. | ||.|||| .||.|...|.||.| .. |
aldllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
2-281 |
2.7e-91 |
301.4 |
In-house |
39-314 (317) |
alignment |
Range on Protein: 2-281
Range on HMM: 39-314/317.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGnrDGRSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDt
..|||| |||| .|. |||.||.|. .|| | |||||||. .|.. ..| .||.||| . ...|||.|||.....|||||| | | ..|||..|||.
elpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrk.fIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwpl.
NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
.... ||..|| |.. | |..|.||. |. ..|.|.....|.| ||| |||.. . .|.| ... . ... | .|||||||||||.||... ||.
getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmle
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQRL
| .... ||... |. | ||..||| .||.|...|.|| | .. |.. |..| . . || . . ..|...|.|...|
qlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllklliplalddvklkekelkll
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
1-255 |
2.1e-89 |
295.0 |
In-house |
34-289 (297) |
alignment |
Range on Protein: 1-255
Range on HMM: 34-289/297.0
AKKPENKIKNRYGNIVTYDHTRVVLkgpggnRDGRSDYINASFLQGFdGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|..|||. |||| .|. ||||||.| |. |||||||...|. . ..|.||.||| . ...|||.|||.....|||||| |.| .|||..|||.
allpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgy.dlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpl
T-NQPKPYGQYTVSLCKNEA--FADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRH--NTAPWIVHCSAGVGRTGAFIV
. .... ||..|| | . | ..|||.||. || ..|.|.....|.| ||| |||.... .|.| ... . .. . | .|||||||||.|.||.
eegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfia
IDAMLRQAK---EKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNL
.| ||.| . . . |||...|. | ||..||| .||.|...|.|| | .. |.... .|
adlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllkl
|
subfamily_PTPRB_pd |
Subfamily PTPRB |
1-244 |
1.2e-88 |
292.0 |
In-house |
46-286 (293) |
alignment |
Range on Protein: 1-244
Range on HMM: 46-286/293.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|....|. |||| ||..|||.|| |. . . ||||||....|. .|...||.|||. . ||||.|||....|.||||| |.|. |.||..|||.
aelavnraknrytnilpydhsrvkLaal..kdesgsDYinanyipgyn.sprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPa
TNQPKPYGQYTVSLCKNEAFADYTVRTFLVTSapSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINES--RHNTAPWIVHCSAGVGRTGAFIVIDA
...| ||. .|.| ..| |...|..... ..|.| . ||||| ||| |||. ....|.| ... .. ....| .|||||||||||.|| .|
deepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdr
MLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALV
.|.. .|. .|||. | . | .| ..|||..||.|||..||. |
llqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
subfamily_Sponge-PTP8_pd |
Subfamily Sponge-PTP8 |
3-264 |
1.9e-88 |
291.6 |
In-house |
43-304 (305) |
alignment |
Range on Protein: 3-264
Range on HMM: 43-304/305.0
KPENKIKNRYGNIVTYDHTRVVLKGPGGNRdgRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN
| .|| |||. .|...|. |. |. . |||||||...|... ||||.||||.. .|||.....|. |.|||||.|.|| |.||..|||..
keankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrk.kkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesk
QP-KPYGQYTVSLCKNEAFADYTVRTFLVTS-APSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNT-APWIVHCSAGVGRTGAFIVIDAM
. | .|...| | .....||. | . .. ..|.| . ||..| |||.||||.||..|.. |.. .. ... | .|||||||||||.||..| .
tekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdia
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEK
| ..|. .|||....... | |..||||.|||||.| |. | . || |.| ||| . ||.|
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvnklkk
|
subfamily_PTPRD_pd |
Subfamily PTPRD |
289-535 |
4.5e-88 |
291.3 |
In-house |
37-282 (564) |
alignment |
Range on Protein: 289-535
Range on HMM: 37-282/564.0
DVRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPR
...|.|. .| .|||. .|.. |. || |. .|..|.| ||||||| ..||.|.|.| ||.||..||. ||||| ... |||||..| |... . .
qftweaankpaNkaKNRyanivaYdhsRVvLs.kvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchk
YWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQqKSGDKAIVVQCSDGVGRSGTLCAI
|||..| |.||...|.|.|| ... .. | | ...| .| . . .|. |.| || ||... .|| |........ ... . |||.|| ||||.|| ..|
YWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfivi
MSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
...||.| |..||..| ||.|| |. |.| ||| |.... | .|.
damlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheaileala
|
subfamily_PTPRG_pd |
Subfamily PTPRG |
1-258 |
1.6e-87 |
289.0 |
In-house |
42-302 (563) |
alignment |
Range on Protein: 1-258
Range on HMM: 42-302/563.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGGNrDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
..||||| |||| |||.||..|| |.. |. ... |||||....|. |..||.|||.. .||||.|.|... ..|||.| | | ..||. |||
sqkpenkrKnRylnivaydrsRvklsplpgk.kkklDYinAnyidGyq.kskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk
tNQPKPYGQYTVSLCKNEAFADYTVRTFLVTS------APSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFI
.... ||. .| | ..| .| |||||. . .... ..|||.| |||.|||.... || | || .... | .||||||||||| .|
.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyi
VIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNV
|.|..|.| .....|.... .. | |...|||..||.|.| |.|||. . |...| .....
vldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqveel
|
subfamily_Nvec-PTP-2_pd |
Subfamily Nvec-PTP-2 |
295-536 |
2.2e-86 |
284.1 |
In-house |
4-244 (250) |
alignment |
Range on Protein: 295-536
Range on HMM: 4-244/250.0
ASRACNASKNRFPDILPLDSHRVALHLSVdKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWPSQGA
| . | |||. ||..||| || |. . | .|||||||.|.|.||.||| ||.||..|| |||||.... ||||||..| |... ...||| ..|
akkpqnkeknryadiialdssrvvLekek.gdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPveka
EEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERV
|.||...|.| ... .. ...|.. .. . |. . . ... ..| | .||.. | ||...|.|||..|.. ..|||| ||||||. .|| .|.||.
ekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerl
KVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLDS
| |.|||||. .| ||. ||.|||.|||| |.| . | .|||
kkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
1-279 |
5.2e-86 |
283.3 |
In-house |
38-313 (314) |
alignment |
Range on Protein: 1-279
Range on HMM: 38-313/314.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGGnrDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
||| ||. |||.|.|..||..||.|. | | ||||||... .. |...|..|||.. |||..|..|.|. ||||| |.| .. || ||||.
akkdenreknrsgdilaydrsrvflitidg..dpssdyinaalidsyk.rpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe
TNQPkpYGQYTVSLCKNEAFADYTVRTFLVTS--APSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDA
. ||. | | . |. |.. ||.| |. . .|.| . |..|. ||| .||..||..|.. ... . . .. . .|||||| ||||.||.||
dtev..ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidi
MLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQ
.| .....|||..| |.. | ..|||.|..||.||. ..||| .|| | | . ..... . .. |. . | . |||
vldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalylesirldpqtnssqlkeefq
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
2-243 |
5.5e-86 |
283.7 |
In-house |
34-272 (273) |
alignment |
Range on Protein: 2-243
Range on HMM: 34-272/273.0
KKPENKIKNRYGNIVTYDHTRVVLkgpggnRDGRSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
..|||| |||| .|. |||.||.| || |||||||...|.. ..| .||.||| . ...|||.|||.....|||||| |.| ..|||..|||..
llpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrk.fiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwple
NQ--PKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRH--NTAPWIVHCSAGVGRTGAFIVID
.. .. ||..|| | . | ..||||||. .|. ..| |.....|.| ||| |||.. . .|.| ... . .. . | .|||||||||||.||..|
ggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfiald
AMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
.|.| .... ||....|. | ||.|||| .||.|...|.|| |
llldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
subfamily_Urchin-PTPRB-like_pd |
Subfamily Urchin-PTPRB-like |
1-241 |
5.5e-85 |
279.9 |
In-house |
42-277 (288) |
alignment |
Range on Protein: 1-241
Range on HMM: 42-277/288.0
AKKPENKIKNRYGNIVTYDHTRVVLKGpgGNRDGRSDYINASFLQGfDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
.....|. |||| ||..||..|| ||. .. .||||||...| .. |||||.|||. . .|||..|.... | |||||.|.|| |.||..||||
grlavnakknRyrnilpyDekrvklkk..leeeagaDYinasyidg.ekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPd
TNQPKPYGQYTVSLCKNEAFADYTVRTFLVTsaPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
...|| ||. || | ... |...|..|. ..... | ||....|||.|||. .. .| ..... . . .| | |||||||||||| ||..||..
adkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdali
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
. .|....|. . | | |...|||. ||.||....|.
daveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
2-243 |
9.8e-85 |
280.2 |
In-house |
51-304 (307) |
alignment |
Range on Protein: 2-243
Range on HMM: 51-304/307.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNrDGRSDYINASFL--------QGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEK
..|||| |||| .|. ||||||.|. ..|. .. |||||||. .|.| ..|.||.||| . ...|||.|.|.....||||||.|.| .||
llpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydl.krkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrek
CHKYWPDTNQPKPYGQYTVSLCKNEAFADYTVRTFLVTSA-PSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIIN--ESRHNTAPWIVHCSAGVGRT
|..||||..... ||..|| | . | ..|||||. || ...| |.....|.| ||| |||.. .|.| ... . |. . | .||||||||||
caqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRt
GAFIVIDAMLRQAKEKKV---VDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
|.||... |||| .. .. ||... |. | ||..||. .||.|...|.|| |
GtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
DSPc_SM00195 |
|
2-242 |
1.1e-84 |
279.2 |
In-house |
22-261 (263) |
alignment |
Range on Protein: 2-242
Range on HMM: 22-261/263.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNrdGRSDYINASFLQGFdGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
.|..|| |||| ||. |||||| || . .. ||||||....| .|||||.||| . ..|||.|||.|....||||| | ||||..|||..
ekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpee
-NQPKPYGQYTVSLCKNEAFA-DYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
.... .|...| | ..| ....||. .| .|.|...||... |||.|||. .. ||.. ... ........| .|||||||||||.|..|| .
sggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
|.. .|.| ||| . |.. | ||.||||..|| ||..|.||.
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
PTPc_SM00194 |
|
2-242 |
1.1e-84 |
279.2 |
In-house |
22-261 (263) |
alignment |
Range on Protein: 2-242
Range on HMM: 22-261/263.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNrdGRSDYINASFLQGFdGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
.|..|| |||| ||. |||||| || . .. ||||||....| .|||||.||| . ..|||.|||.|....||||| | ||||..|||..
ekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpee
-NQPKPYGQYTVSLCKNEAFA-DYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
.... .|...| | ..| ....||. .| .|.|...||... |||.|||. .. ||.. ... ........| .|||||||||||.|..|| .
sggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
|.. .|.| ||| . |.. | ||.||||..|| ||..|.||.
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
subfamily_PTPRA_pd |
Subfamily PTPRA |
1-278 |
5.1e-84 |
277.0 |
In-house |
53-330 (330) |
alignment |
Range on Protein: 1-278
Range on HMM: 53-330/330.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgrSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|.| ||| |||. ||. ||..||.| |. . ||||||||..|. .|.|||||| | . .|||.|.|. . . ||||| | | .|||..||||
askeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfidGykek.dkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPd
TNQpKPYGQYTVSLCKNEAFADYTVRTFLVTSAPS----NEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVI
||. .|.. ... ||||| |||. | ...| . |.||| ||| ||| . .|.. ||. . . .. | .|||||||||||.|||.
eGl.vtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivl
DAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEF
||.| . | ...||... |. | ||.||||. ||.||....|| . | |.... | . . || . .. . | | ||
davlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekhlqklynkitgtdkigleeef
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
1-251 |
1.8e-83 |
275.1 |
In-house |
44-287 (315) |
alignment |
Range on Protein: 1-251
Range on HMM: 44-287/315.0
AKKPENKIKNRYGNIVTYDHTRVVLkgPGGNRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
||| ||| |||| ||..||..|| | | . | |||.||.|..|.. ...||||||| | .|||..|..| .. |||||.|.|| |.|. |||||
akkienkqknryiniiaydksrvql..pllendphsdyvnanfidGyn.kkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpd
TnqPKPYGQYTVSLCKNEAFADYTVRTFLVTSApsNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
||..||.. ..| . .|||||. |.. .. | ..|.|.| ||| |||.|..... . ... . .. .|||||||||||.|| .||.|
k..kviyGkitvtrkseevnteytvrtlsvvfg..dnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavl
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQ
||. ....|.||... | | .|||. .|| ||. |.||..||| | |
dqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsia
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
2-245 |
3.7e-83 |
274.7 |
In-house |
52-291 (297) |
alignment |
Range on Protein: 2-245
Range on HMM: 52-291/297.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNrDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKeKCHKYWPDT
..|||| |||| .|. |||.||.||...| | |||||||...|.| ...|.||.||| . ...|||.|||.....|||||| |.| .. ||..|||..
llpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpee
NQpkPYGQYTVSLCKNEAFADYTVRTFLVTSapSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRH--NTAPWIVHCSAGVGRTGAFIVIDAM
. ||..|| | | | ..|||||. || ..| |.......| ||| |||.... .|.| ... . .. . | .|||||||||||.||... |
gg..tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylm
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVC
|.| .... ||... |. | ||..||| .||.|...|.|| | .
leqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
|
Y_phosphatase |
Protein-tyrosine phosphatase |
6-241 |
5.3e-83 |
273.4 |
Pfam-A |
1-235 (235) |
alignment |
Range on Protein: 6-241
Range on HMM: 1-235/235.0
NKIKNRYGNIVTYDHTRVVLkgpgGNRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWP-DTNQP
|| |||| .|. ||.||| | ...|.||||||....|.. ..||.||.|||.. ...|||.|||||...|||||| | | ..|||..||| .....
nkkknRykdilpydktrvkl....kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeees
KPYGQYTVSLC-KNE-AFADYTVRTFLVTSAPSN-EQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
. ||...| | |.. . ..||.|.. ... .. |.| ..|.|.| |||.|||. ....|.. .|. ........| .||||||||||| |...|..|.
ltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldille
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
|..... ||....|. | ||.|||. .||.|...|.||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
Y_phosphatase |
Protein-tyrosine phosphatase |
6-241 |
5.3e-83 |
273.4 |
In-house |
1-235 (235) |
alignment |
Range on Protein: 6-241
Range on HMM: 1-235/235.0
NKIKNRYGNIVTYDHTRVVLkgpgGNRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWP-DTNQP
|| |||| .|. ||.||| | ...|.||||||....|.. ..||.||.|||.. ...|||.|||||...|||||| | | ..|||..||| .....
nkkknRykdilpydktrvkl....kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeees
KPYGQYTVSLC-KNE-AFADYTVRTFLVTSAPSN-EQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
. ||...| | |.. . ..||.|.. ... .. |.| ..|.|.| |||.|||. ....|.. .|. ........| .||||||||||| |...|..|.
ltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldille
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
|..... ||....|. | ||.|||. .||.|...|.||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
261-534 |
8.4e-83 |
273.5 |
In-house |
31-299 (308) |
alignment |
Range on Protein: 261-534
Range on HMM: 31-299/308.0
KLEKIRPREQVSGYESEFQRLSIFWLspDVRVESASRACNASKNRFPDILPLDSHRVALhlsvdkDPGADYINASFAHAY--RERNAFILTQAPLEDTIA
|... . . ...| ||..| . . ..|.. .| .|||..||||.|. || | |.| ||||||. . | . ...||.||.||..|..
llkllekaldlglleeefeellsvkp..lleysvallpenkdkNrykdilpydhsRVkl......degsdYInAsyvdgyssklprkfIatqgPlpntve
SFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQ---GAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPL
.||||| ... .||||..|.| . | ...|||. | .|||...|.| .|. .. .. | . .| .|.. .. ||. ||| ||.||..| .|| .
dFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldf
LNDIQTSQqksGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
|. ...|. ... ||| ||.||||.||..|. ..|... |. ||||.||| || |||.|.|.|||.|.|.. | ||
lelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleyl
|
subfamily_Choan-PTP-1_pd |
Subfamily Choan-PTP-1 |
2-243 |
1.3e-82 |
272.1 |
In-house |
37-276 (281) |
alignment |
Range on Protein: 2-243
Range on HMM: 37-276/281.0
KKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
|..||. |||| ||| ||.|||... ... .|||||.|..|..| .|.|||.|||| |...||||||... |.|||.| ||..| |||.||||
kadenvlknrYsnivaYDatrvkvtpn..eenkntDYinanfvpgykg.ekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPdd
NQPKPYGQYTVSLCKNEAFADYTVRTFLVtSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNT-APWIVHCSAGVGRTGAFIVIDAML
|. ||..||. ..|. | | |.| . .. |.|.| . | ..| |||.|||. ....| |||.. . ....| || ..||||||||||..| .| ..
nselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlv
RQAKE-KKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
..... .. .|. . |. | .| |||| || |...|||.||
kaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
2-240 |
1.9e-82 |
271.7 |
In-house |
50-294 (306) |
alignment |
Range on Protein: 2-240
Range on HMM: 50-294/306.0
KKPENKIKNRYGNIVTYDHTRVVLKgpgGNRDGRSDYINASFLQ-GFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
.||||| |||| ||. .|||||.|| . ||||||.... . |. |.|||.|| .| |||.||||| . ||||.| .| .|||| .||||
akpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPd
TNQPKPYGQYTVSLCKNEAFADYTVRTFLVT-SAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNT----APWIVHCSAGVGRTGAFIV
... . ||...|. ..... |||..|...|. ..|.| ..||||..|||.|||. ||| | ... ..... . | .||||||.||||.|||
eeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiv
IDAMLRQAKEKKV---VDIYNYVRATRGDRPNMVQTKDQYVFIHRAVL
||..|.. ..|.. .||.. |. .| | .|||..|| |...|.
iDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
2-241 |
3e-82 |
271.5 |
In-house |
41-275 (278) |
alignment |
Range on Protein: 2-241
Range on HMM: 41-275/278.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgrSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPdt
..|||| |||| .|. |||.||.|. || | |||||||.. |.. ..| .||.||| . ...|||.|||......|||||.| | ...||..|||
llpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprk.fiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp..
NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
.... ||..|| | | | ..||||||. || ..| |....||.. ||| ||| . .|.| |.... ... | .|||||||||||.||... .|.
ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllle
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
|.. . ||... |. | ||..||| .||.|...|.||
qlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
247-534 |
5.1e-82 |
270.9 |
In-house |
2-286 (288) |
alignment |
Range on Protein: 247-534
Range on HMM: 2-286/288.0
STDIQAPNLRNVMTKLEkirpREQVSGYESEFQRLSIFWLSpdVRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAF
.|.|.. .|.... || . ...|.. ||..| .. . . . .|.. .| .|||..||||.|. || |. ..|...| ||||||. . |. ..|
dteisveellklvlkll....angltglleefeellsllpd..ltlsaallpenleknRysdilpydhsRVkLs.vldgvegsdYinAsyidgynlkrkf
ILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTK----GKSTPQRICHFQVTNWSD
|.||.||..|...||||| ... .||||..|.| . | ...|||..| ..|| |.|.| .|. .. .. | . .| . |....... ||..||| |
IatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpd
HSVPDKPLDLLPLLNDIQTSQQkSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
|.||| | .|| .|........ ||.. .|| ||.||||.||..|. ..|... |..|||..||| || |||.|.|.|||.|.|.. | ||
hgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
subfamily_Ptp69D_pd |
Subfamily Ptp69D |
2-262 |
2.3e-80 |
265.0 |
In-house |
44-305 (307) |
alignment |
Range on Protein: 2-262
Range on HMM: 44-305/307.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGnrDGRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
.| ||..|||| .|...|.|||.|| | . ||||||||..|.. . ||.||||.||| .|||.|... .||||. | | ...||.||||.
ekkenalknRyedikafDktRvkLkking..kedsdYinasfikgykek.kkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie
nQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAP-----SNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVI
. . ||. | | ..| ||. |.. |. ...| . |||.| |.| ||. |...|.. ... . ..| .| .|||||||||.| |. .
.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifval
DAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKL
| .| | |. . |||.. |. | .|. .|| .||||..||.|. | ||.. .| . . .|
dsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledaierl
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
275-534 |
1.1e-79 |
263.1 |
In-house |
3-274 (284) |
alignment |
Range on Protein: 275-534
Range on HMM: 3-274/284.0
ESEFQRLSIFWLSPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDKDPGADYINASFAHAY-----RERNAFILTQAPLEDTIASFWRMVVDYDL
| ||..| .. .. . .. | . .| ||||..||||.|. || |. ..... ||||||. . | . ...||.||.||..|...||||| ...
eeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnv
GTIVMLNSLDEED-EHFPRYWPSQG-AEEYGGIKVELQEEDDKSFFISRRFDITTKG-KSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQK-S
.||||..|.| . | ...|||. | .||...|.| .|. |. .. |.. .| .| .. . .. ||..|.| ||.||. | ||| .|......... .
rvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlp
GDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEH---VVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
|.. ||| ||.||||.||..|.. ..|... |. .|||..||| || |||.|.|||||.|.|.. | ||
gggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleyl
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
3-245 |
2.6e-79 |
261.7 |
In-house |
30-274 (278) |
alignment |
Range on Protein: 3-245
Range on HMM: 30-274/278.0
KPENKIKNRYGNIVTYDHTRVVlkgpggnrdgrsDYINASFLQGFdgtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDtN
...|. |||| .|. |||.||. ||||||...|. |||.||.||| . ..|||.|.|.....||||||.|.|...|||..|||. .
ylgnldknRykdilpydhsrVk............dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe.g
QPKPYGQYTVSLCKNEAFADYTVRTFLVTSA----PSNEQRFIYQYHFTVWPDKGVPQYA--TAVLRFRKKIINESRH-------------NTAPWIVHC
... ||..|| | . | . |||.||.||| ...|.|.....|.. ||| ||| . . .|.. . | . .. . | .|||
gsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHC
SAGVGRTGAFIVIDAMLRQAkeKKVVDIYNYVRATRGDRPN-MVQTKDQYVFIHRAVLEALVC
||||||||...... ||.. ...||....|. | ||. .||...||.|.....|| | .
saGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
subfamily_Anemone-PTP-5_pd |
Subfamily Anemone-PTP-5 |
274-535 |
1.9e-78 |
258.8 |
In-house |
25-284 (319) |
alignment |
Range on Protein: 274-535
Range on HMM: 25-284/319.0
YESEFQRLSIFWLSpdvRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIV
| ||. |.. ..|||. | .|||...||. | ||.| ..| .|.||||||| .|.||..|| ||||||.|| ||||| ... ..|
lekefkllkeavnd...tfdsaskeenkkknryqnilaydrtrvvls.eldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivv
MLNSLDEEDE-HFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKST-PQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIV
||. | |. . .. .|||.. |||| . |.|.||. .. .| |.. . .| .. ||| |.|.|| ||.| . || ||..|. |..|. .. ||
mltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPiv
VQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
| ||.|||| || ... ..|||| | |.|||. |..||. |. |.. |||||.|.. |....
vhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleave
|
subfamily_Urchin-PTPRA_pd |
Subfamily Urchin-PTPRA |
4-259 |
5.6e-78 |
257.4 |
In-house |
59-307 (319) |
alignment |
Range on Protein: 4-259
Range on HMM: 59-307/319.0
PENKIKNRYGNIVTYDHTRVVLKGPGGNRdgRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTgliegsKEKCHKYWPDTNQ
..|| |||..||...|...| |. | ||||||||..|. ..|||||||| . . .|||.|.|. .|| ||.|| |.|| .||| .
dqnkdknriinilafdknvvklerliGee..fsdyinasfvtGyq.rkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkiv
PKpYGQYTVSLCKNEAFADYTVRTFLVTS-APSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKK--IINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
| .... |.. | |.|.|| . .. . ...| | |.|| |||.|||.|.. ..|. || ... .. |. .|||||||||||..||.|..|
ik.eerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvll
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVM
. ||.| ||.||.|| | .|...|| || ||. |.|| . | .|. |.. .
drmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayl
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
2-243 |
5.8e-78 |
257.2 |
In-house |
7-246 (249) |
alignment |
Range on Protein: 2-243
Range on HMM: 7-246/249.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGnrDGRSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDt
..|||| |||| .|. |||.||.|. .| |||||||.. |.. ... .||.||| . ...|||.|.|.....|||||| | | .|||..|||.
llpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRH--NTAPWIVHCSAGVGRTGAFIVIDAM
.... ||..|| | . | ..||||||. .| .| | ......| ||| |||.. .|.| ... . .. . | .|||||||||||.||... |
ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
|.| .... ||....|. | ||..||. .||.|...|.|| |
leqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
2-241 |
1.2e-77 |
255.9 |
In-house |
5-241 (245) |
alignment |
Range on Protein: 2-241
Range on HMM: 5-241/245.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgrSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDt
..|||| |||| .|. ||||||.|. .||. | |||||||. |.. ||| .||.||| . ...|||.|.|......||||| . | ...||..|||.
llpenkdknrysdilpydhtrvklspdggdld..sdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.
NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESR-HNTAPWIVHCSAGVGRTGAFIVIDAML
.... ||..|| | . | ..||||||. || ...|.|....||.. ||| ||| . .|.| . . . . .. | .|||||||||||.||... ||
gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
.|... . |.... |. | ||..||| .||.|...|.||
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
277-534 |
1.6e-77 |
256.2 |
In-house |
23-276 (317) |
alignment |
Range on Protein: 277-534
Range on HMM: 23-276/317.0
EFQRLSIFwlSPDvRVESASRACNASKNRFPDILPLDSHRVALhLSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLN
||..| . ..| . |.. .| .|||.|||||.|. || | ....|.. ||||||. . ......||.||.||..|...||||| ......||||.
efedllsl..kld.tysvaelpenkdknrypdilpydhsRVkL.splggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLt
SLDEE-DEHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQkSGDKAIVVQCS
.|.| .| . .|||... .||...|.|..|. .. .. |.. .. .|.|.. .. ||. |.| ||.||. | .|| .|. ...... .... ..| ||
eleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCs
DGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.||||.||..|. ..|... |. |||..||| || |||||.|.|||.|.||. | ||
aGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
258-534 |
1.8e-77 |
256.0 |
In-house |
18-289 (297) |
alignment |
Range on Protein: 258-534
Range on HMM: 18-289/297.0
VMTKLEKIRPREQVSGYESEFQRLSIFWLSpdvrVESASRACNASKNRFPDILPLDSHRVALHLSVDKDPGADYINASFAHAYRE-RNAFILTQAPLEDT
|.. | ..... . .... ||..| . . . | . .| .|||..||||.|..|| |. . |.. ||||||. |. ..||.||.||..|
vldlllllekansktllllefeellslkpd....ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpet
IASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWPSQGAeEYGGIKVELQEEDDKSFFISRRFDITTkgKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLN
...||||| ... .||||..|.| . ....|||. | .||...|.| ... .. .. | . .| .. . . |||.|.| ||.||. . .|| .|.
vedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslelllefle
DIQTSQQKS-GDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
... .... ... ..| ||.||||.||..|. ..|... |. |||..||| || |||||.|..||.|.||. | .|
lvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
269-534 |
1.9e-77 |
255.8 |
In-house |
10-277 (297) |
alignment |
Range on Protein: 269-534
Range on HMM: 10-277/297.0
EQVSGYESEFQRLsiFWLSPDVRVESASRACNASKNRFPDILPLDSHRVALhlsvdKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYD
. .....||..| . | .. . |.. .| .|||..||||.|. || | .|.| ||||||. |. ..||.||.||..|...||||| ...
lflalllkefeel..lpllllgslsvallpenleknRykdilpydhtRVkl.....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn
LGTIVMLNSLDEE-DEHFPRYWPSQ--GAEEYGGIKVELQEEDD--KSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQ
.||||..|.| | ...|||. . .||...|.|.... .. .. | . .| .|.. . .. ||..|.| ||.||. | .|| ... ... ..
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlk
KS-GDKAIVVQCSDGVGRSGTLCAIMSVIERVK---VEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.. ... ..| ||.|||||||..|. ...... |. ||...||| || |||||.|||||.|.|.. | .|
llpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallell
|
subfamily_Urchin-PTP-6_pd |
Subfamily Urchin-PTP-6 |
6-279 |
4.3e-77 |
254.3 |
In-house |
43-312 (515) |
alignment |
Range on Protein: 6-279
Range on HMM: 43-312/515.0
NKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD-TNQP
| ||||.||. || .|| |. | . |||.|||....|| | |||.||| . | ||||..|.||. . |.|.| | || | || ||||| .
nfkknryknilPydsvrvklevi..ndnPhsdyfnasyipsfdn.dkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgds
KPYGQYTVSLCKNEAFADYTVRTFLVTSApsNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAK
.|.. |.| || .. . |.. |. .. | . |.||| |||||||. ....|.. |.. . . | | |.|||||||||| .| || .. .||
vkfGsikvelvsleactggikrkltvlkg..ddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahak
EKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQ
. ..||..|.|. | .|| .|||..|| ||. |||| | | | . . . | . | |||
ttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrskmtkefq
|
subfamily_Urchin-PTP-8_pd |
Subfamily Urchin-PTP-8 |
4-259 |
6.5e-77 |
253.8 |
In-house |
23-271 (284) |
alignment |
Range on Protein: 4-259
Range on HMM: 23-271/284.0
PENKIKNRYGNIVTYDHTRVVLKGPGGNRdgRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTgliegsKEKCHKYWPDTNQ
..|| |||.|.|...|...| |. |. ||||||||..|. ..||||.||| . . .|||.|.|. .|| ||.|| |.|| .||| .
dqnkdknrighilafdknvvklerliGee..fsdyinasfitGyq.rkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkiv
PKpYGQYTVSLCKNEAFADYTVRTFLVTS-APSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKK--IINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
| .... |.. | ..|.|| . .. . ...| | |.|| |||.|||.|.. ..|. || ... .. |. .|||||||||||..||.|..|
ik.eerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvll
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVM
. ||.| ||.||.|| | .|...|| || ||. |.|| . | .|. |.. .
drmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayl
|
DSPc_SM00195 |
|
288-534 |
1.3e-76 |
252.7 |
In-house |
16-262 (263) |
alignment |
Range on Protein: 288-534
Range on HMM: 16-262/263.0
PdvRVESASRACNASKNRFPDILPLDSHRVALHLSVDKdPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDE-EDEHFP
....| . | ||||. .||| |. || |. . .| .| |||||.. .......|.||.||..|...|||||.. . .||||.. .| . |.
k..etteaekkknksknRyknilpydhtrVklkkeekk.egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
RYWPSQ--GAEEYGGIKVELQEEDDKS-FFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSgDKAIVVQCSDGVGRSGT
||||.. | |..| |.|.|.|.. |. .| | . .| .||...... ..|..|| ||.|||.. ..| ||. ...|...| .. |||.||.||||.||
rywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgt
LCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
...| ....... |. ||.|. ||.|| .|||.|.|||||.|.|.. |.|.
fvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
PTPc_SM00194 |
|
288-534 |
1.3e-76 |
252.7 |
In-house |
16-262 (263) |
alignment |
Range on Protein: 288-534
Range on HMM: 16-262/263.0
PdvRVESASRACNASKNRFPDILPLDSHRVALHLSVDKdPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDE-EDEHFP
....| . | ||||. .||| |. || |. . .| .| |||||.. .......|.||.||..|...|||||.. . .||||.. .| . |.
k..etteaekkknksknRyknilpydhtrVklkkeekk.egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
RYWPSQ--GAEEYGGIKVELQEEDDKS-FFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSgDKAIVVQCSDGVGRSGT
||||.. | |..| |.|.|.|.. |. .| | . .| .||...... ..|..|| ||.|||.. ..| ||. ...|...| .. |||.||.||||.||
rywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgt
LCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
...| ....... |. ||.|. ||.|| .|||.|.|||||.|.|.. |.|.
fvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
270-534 |
2.6e-76 |
252.0 |
In-house |
10-272 (273) |
alignment |
Range on Protein: 270-534
Range on HMM: 10-272/273.0
QVSGYESEFQRLsiFWLSPDVRVESASRACNASKNRFPDILPLDSHRVALhlsvdKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDL
...... ||..| . | |.. . |.. .| .|||..||||.|. || | .|.| ||||||. |. ..||.||.||..|...||||| ...
gltllleefell..lslkplltysvallpenkdknrykdilpydhsrvkl.....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnv
GTIVMLNSLDEE-DEHFPRYWPSQG---AEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKS
.||||..|.| | ...|||. | ..|| ..|.| .|. |. .. | . .| .| . . ..||..|.| ||.||. . .|| ....... ....
rviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkaleal
-GDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
... .|| ||.||||.||..|. ...... |. |||..||| || |||.|.|.|||.|.|.. | ||
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
subfamily_Anemone-PTP-6_pd |
Subfamily Anemone-PTP-6 |
276-536 |
5.4e-76 |
250.7 |
In-house |
24-282 (318) |
alignment |
Range on Protein: 276-536
Range on HMM: 24-282/318.0
SEFQRLSIFWlSPDVRVESaSRACNASKNRFPDILPLDSHRVALHLSVdKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVML
.|..||| . ...| .|. |||. .||. |. ||.|. . ...|.|||||.. ||...|.| .|||| .|| ||||| . . .||||
eeyerlsrse.etvtslks.lepvnkaknryanilaydhtrvkLqmle.geegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivml
NSLDEED-EHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIVVQC
. |. . |||||.|...|| ..|||.|| . | .. |.| .| .... . . ...|.|.|..||... .|| |. .... ||||| ..||| |
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhC
SDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLDS
| |||| |. .|. ...||.| | .||||| ||.|| |. | | .||.|.||| | .| |
saGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealas
|
subfamily_Urchin-PTP-1_pd |
Subfamily Urchin-PTP-1 |
1-255 |
7.2e-76 |
250.0 |
In-house |
39-289 (315) |
alignment |
Range on Protein: 1-255
Range on HMM: 39-289/315.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|....| ||||.||. .|..||.|. . . |||||||.....| | |||.||| . | ||||.||.||. . |||.| . || | || .||||
aretinfkknryknilPldsarvklevi..ddsPdsdyinasyiksvdd.dkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPd
-TNQPKPYGQYTVSLCKNEAFADYTVRTFlVTsAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
. .|.. |.| . || .| ..| . || |.|.| . |..|| ||||||.. ....|.. |.. . .... . .||||||||||| .| || .
rkadsvefGsikvellsleadtdgvarkl.vt.rkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidev
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNL
. |.|....||..|.|. | .|| .|||...| ||. |||| | | | ..
vaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihf
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
2-242 |
2.6e-75 |
248.0 |
In-house |
36-276 (290) |
alignment |
Range on Protein: 2-242
Range on HMM: 36-276/290.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNRdgRSDYINASFLQGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
.|.||. |||| .|. ||..||.|. .. ||||||.|..| .| ...|||||||. ||||.|.|. . ...||. ..| | ||..|||..
ekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgveg.kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpee
NQPKP-YGQYTVSLCKNEAFA-DYTVRTFLVTSApsNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
.. . .|...|.| ...|. |...||. |. .|.| .||.|.| |||.|||. |. .|.. ... . ... || .|||||||||||. |.|| .
geeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyv
LRQAKEKKV---VDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
.. |..|. .|... |. | .|. .||||.||.....||.|
rellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
260-533 |
3e-75 |
249.1 |
In-house |
15-303 (307) |
alignment |
Range on Protein: 260-533
Range on HMM: 15-303/307.0
TKLEKIRPREQVSGYESEFQRLSIFWLSPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDKDPGADYINASFA--------HAYRERNAFILTQA
.| ...... ..|.. ||..| .. . ..|.. .| .|||..||||.|..|| |. ..... ||||||. . |. ..||.||.
lllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqg
PLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQGAE-EYGGIKVELQEEDDKSFFISRRFDITTK-GKSTPQRICHFQVTNWSDHSVPDKP
||..|...||||. ... ..||||..|.| .| ..|||. | | .|| ..|.| .|. .. .. |.. .| . |.. . ...||. |.| ||.||. .
PlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsf
LDLLPLLNDIQTSQQKS-GDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHV---VDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
.|| ... ... .... ... ..| ||.||||.||..|. ...... |.. ||...||| || |||||...|||.|.|.. | .
eelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
2-241 |
1.3e-74 |
246.0 |
In-house |
6-240 (243) |
alignment |
Range on Protein: 2-241
Range on HMM: 6-240/243.0
KKPENKIKNRYGNIVTYDHTRVVLkgpggnrDGrSDYINASFLQGFDgtpkKYIAAQGPVEPSCDD----FWQMVWQERCSVIVMLTGLIEGSKEKCHKY
..|||. |||| .|..|||.||.| .| ||||||.. .... ..|| ||| . ...| ||.|.|.....|||||| |.| ..|||..|
llpenlsknrysdilpydhsrvkl.......eg.sdyinanliyvtp....rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPdtNQPkPYGQYTVSLCKNEAFADYTVRTFLVTSAP-SNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINE--------SRHNTAPWIVHCSAGVG
|| .. ||..|| | . | ..||||||.|.. . ....|....||.. ||| |||. . .|.| ..... ... | .||||||||
wp..gev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTGAFIVIDAMLRQAkekKvVDIYNYVRATRGDRPN-MVQTKDQYVFIHRAVLE
|||..|... ||.. . ||....|. | ||. .||| .||.|...|.||
RtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyealle
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
272-533 |
2e-74 |
245.9 |
In-house |
20-276 (278) |
alignment |
Range on Protein: 272-533
Range on HMM: 20-276/278.0
SGYESEFQRLSIFWLspdVRVESASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGT
.... ||..| |.| . | . .| .|||..||||.|..|| |.| ...|.. ||||||. |. ..||.||.||..|.. ||||| ... |
tllllefeellsfkl...dtysiallpenkdknrykdilpydhsrvklsl.lggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtt
IVMLNSLDEED-EHFPRYWPsQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQkSGDKAI
||||..|.| . . . .||| .| ..||...|.|..|. .. .. | . .| .|.. .. ..|.. ..| ||.||. . .|| .|..... .. . ....
ivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpv
VVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
.| ||.||||.||..|. ..|... |. ||...||| || |||||.|..||.|.|.. | |
lVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
subfamily_Sponge-PTP11_pd |
Subfamily Sponge-PTP11 |
4-244 |
6.1e-74 |
243.5 |
In-house |
44-284 (290) |
alignment |
Range on Protein: 4-244
Range on HMM: 44-284/290.0
PENKIKNRYGNIVTYDHTRVVLKGPGGNRDGRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQ
..|| .||. ||| || |..|. .|..| .||||....|. |.|||.||||. |||...|||....||||| || |.||..||||...
ssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykek.kqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdt
PKpYGQYTVSLCKNEAFADYTVRTFLVTSAPS-NEQRFIYQYHFTVWPDKG-VPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
. ||.... | ..|.. .|. |.. |.. | .... . ||..| |...| |....| .| ... . .. .. . .||||..|||.. |.... .
ka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattin
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALV
..| . |.|... .. | .|..|||..|| .|.. ||..|
kcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
subfamily_PTPN3_pd |
Subfamily PTPN3 |
1-242 |
3.6e-73 |
240.9 |
In-house |
36-274 (280) |
alignment |
Range on Protein: 1-242
Range on HMM: 36-274/280.0
AKKPENKIKNRYGNIVTYDHTRVVLKgpggnrDGRSDYINASFLQ-GFDG--TPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKY
|.|||| |||| .|..||.||| || ....|||||.... .. . ..|||.|||.. .. |||||||....|.||||| |.| . |||.|
arkpenlsknryrdilpydatrvklk......esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqy
WPDTNQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVID
||.|.. ||...| . |... | .| .... . ..|.| | | .. |||.|||. .. .|.| ... . . .. | .||||||.|||| .|...
WPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlille
AMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
| ... | . . || | | ..|||..|| |. |.|..
talalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
subfamily_Sponge-PTP8_pd |
Subfamily Sponge-PTP8 |
272-534 |
6e-73 |
240.7 |
In-house |
22-283 (305) |
alignment |
Range on Protein: 272-534
Range on HMM: 22-283/305.0
SGYESEFQRLSIFwlSPDVRVEsaSRACNASKNRFPDILPLDSHRVALHLSVDKDpGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGT
.|.| ... | . . |. .. |..|||. .| .|| .|. | . ..| .||||||. ..|......|..|.||..|.| |||..|.. |
kgleaqykslyee..eesidvg..kkeankaknrlkeitlldddriiltekesld.dsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvst
IVMLNSLDEEDEH-FPRYWPSQGAE--EYGGIKVELQEEDDKSFFISRRFDITT-KGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGD
|||| | |.... .||| . .| |.| ..|||..| | .| |.. |.. .... . . ..|.|.| || ||... || |....| .|.|. .
ivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkg
KAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
....| ||.||||.|. .|. .||.| | |||||. .|.|| .|...|.||.|| |..|. ..
vpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
|
Y_phosphatase |
Protein-tyrosine phosphatase |
300-531 |
6.7e-73 |
240.3 |
Pfam-A |
1-234 (235) |
alignment |
Range on Protein: 300-531
Range on HMM: 1-234/235.0
NASKNRFPDILPLDSHRVALhlsvDKDPG-ADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWP--SQGAE
| .|||..|||| |. || | ....| |||||.. . |.| ..||.||.||..||..|||||.... .||||.||.|. .|....||| ... .
nkkknRykdilpydktrvkl....kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
EYGGIKVELQ--EEDDKSFFISRRFDITTKGKS-TPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQqKSGDKAIVVQCSDGVGRSGTLCAIMSVIE
.|| |||||. |..|.. .. | .... |... .... ....||| ||.||..| .|| |......|. .. .. .||.||.||||.||..|.. ..|
tygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldille
RVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
... |. |||.|.||.|| .|||.|..||||.|.|.. |
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
Y_phosphatase |
Protein-tyrosine phosphatase |
300-531 |
6.7e-73 |
240.3 |
In-house |
1-234 (235) |
alignment |
Range on Protein: 300-531
Range on HMM: 1-234/235.0
NASKNRFPDILPLDSHRVALhlsvDKDPG-ADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWP--SQGAE
| .|||..|||| |. || | ....| |||||.. . |.| ..||.||.||..||..|||||.... .||||.||.|. .|....||| ... .
nkkknRykdilpydktrvkl....kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
EYGGIKVELQ--EEDDKSFFISRRFDITTKGKS-TPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQqKSGDKAIVVQCSDGVGRSGTLCAIMSVIE
.|| |||||. |..|.. .. | .... |... .... ....||| ||.||..| .|| |......|. .. .. .||.||.||||.||..|.. ..|
tygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldille
RVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
... |. |||.|.||.|| .|||.|..||||.|.|.. |
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
subfamily_Sponge-PTP10_pd |
Subfamily Sponge-PTP10 |
4-249 |
5.2e-72 |
237.2 |
In-house |
45-284 (287) |
alignment |
Range on Protein: 4-249
Range on HMM: 45-284/287.0
PENKIKNRYGNIVTYDHTRVVLKgpggnrDGRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQ
..|| |||. .|. .| ||.|| . . |||||.|..|. |..|.|..|. .||....... ..||||. . | .|.|..|||...
sqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykek.kafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks
pKPYGQYTVSLCKNEAFADYTVRTFLVTSAP-SNEQRFIYQYHFTVWPDKG-VPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
.|.|...| ..| |.|..|.. |. ..... . ||..| |...| |....| .| . ... .. .. .. .||||..|||.. |. .. ..
.vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattin
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTD
..|. |.|... .. | .|..||| .|| || .||| | ...|
kckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfety
|
subfamily_Urchin-PTP-5_pd |
Subfamily Urchin-PTP-5 |
5-253 |
1.4e-71 |
236.1 |
In-house |
50-294 (297) |
alignment |
Range on Protein: 5-253
Range on HMM: 50-294/297.0
ENKIKNRYGNIVTYDHTRVVLKGpgGNRDGRSDYINASFLQGFDGtpkKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKeKCHKYWPDTNQp
| |.|| ||. || || |. | | |||.||||..|. ..|. | | . . .|||.||..|. |.||||. . |. | || .||.|.
vnfeksRYkniLPydssRvkLai..vnddpdsDyvnasfvkgnkh...rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgv.
KPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQ--YATAVLRFRKKIINESRHNTA-PWIVHCSAGVGRTGAFIVIDAMLR
...|. .| | . . |.. || . .|.. ||.|. |||| |.. |...| . . . .. .|. | .|||.||||||| .. || ..
ttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvva
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAP
.||..| |||...|. | .||..||||.|| |.. ||||||.. |.|||
eakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqas
|
subfamily_Urchin-PTPRB-like_pd |
Subfamily Urchin-PTPRB-like |
266-532 |
1.9e-71 |
235.4 |
In-house |
15-277 (288) |
alignment |
Range on Protein: 266-532
Range on HMM: 15-277/288.0
RPREQVSGYESEFQRLSIfwLSPDVRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVV
... .|...|.. |. | . |. ...| ||.|||...|||.| .|| |. ... .||||||||. . .......| ||.|| ||. ||..|
ksarnrtgfseeynsLaa..lektksvtagrlavnakknRyrnilpyDekrvklk.kleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvy
DYDLGTIVMLNSL-DEEDEHFPRYWPSQGA-EEYGGIKVELQEEDDKSFFISRRFDITtkGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQ
... |||||..| ...... .|||... ..|| ..|.|.|. .. |. |.. . | | .| ..| . |.||.||. .|| ||. .....|
enktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
KSgDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLA
. . |.|.||.||||.|| |. .|..|. | ..||. .|..|| .|. |.||.|| |.|.| |
ad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
|
subfamily_Urchin-PTP-3_pd |
Subfamily Urchin-PTP-3 |
1-279 |
2.1e-71 |
235.7 |
In-house |
43-324 (325) |
alignment |
Range on Protein: 1-279
Range on HMM: 43-324/325.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGgnRDGRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDDFWQMV--WQerCSVIVMLTgLIEGSKEKCHKYW
| ||||| |||. |.|..|..||||. . |. |||||||.|. . . . ..||| | . .|.|..| |. |||.|.| ... |..| .||
amkpenkaknrfknvvaldksrvvletkk..ddpssdyinasylrddkkk.dvflaaqaPltatindlWrlvldWr..csvvvvln.eldlgkdrcavyw
PDT-NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKII--NE----SRHNTAPWIVHCSAGVGRTG
|. . | .| |.| | ..|| | . | . | | . |... |.| ||... .... . . . .| . ..| .|||||||||||
pkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtG
AFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQ
.|| . ..| . |. |||...|. | |||.||.| |||..|. |. ||...| ||. .. .. |.. | | | ||.
vfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeaklsslqernpltqklniekefe
|
subfamily_PTPRA_pd |
Subfamily PTPRA |
291-533 |
7.9e-70 |
230.3 |
In-house |
49-294 (330) |
alignment |
Range on Protein: 291-533
Range on HMM: 49-294/330.0
RVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYW
.| ||. | |||...||| | || | .. . .||||||| . |.|.. || .| |.|.|. ||||. ... ||||| |.| . | .||
tlelaskeenkeknrvvnilPydfsrvils.vkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqyw
PSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKST----PQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDkAIVVQCSDGVGRSGTLC
|..|. || |.||...| . | | .. ....| .. . | | | | || .| .| ||. ... .|.|.. .||| || ||||.||..
PdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfi
AIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
.. .|.|||| |..||||..||.|| || | |.|||.|.| | | |
vldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
281-533 |
1.8e-69 |
229.5 |
In-house |
14-271 (278) |
alignment |
Range on Protein: 281-533
Range on HMM: 14-271/278.0
LSIFWLSPDVRVESASRACNASKNRFPDILPLDSHRVAlhlsvdkdpgaDYINASFAHAYreRNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDE
...|.. ... | . .|..|||..||||.|. || ||||||. . | ...||.||.||..|.|.||||. ... .||||..| |
efllllgipseitpalylgnldknRykdilpydhsrVk...........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelve
E-DEHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTK----GKSTPQRICHFQVTNWSDHSVPDKP--LDLLPLLNDIQTSQQ----------
|....|||..| ..||...|.|..|. . .. |.. .| .. ..|.. ..| ||.||. | .| ||. |. ..
lgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl
--KSGDKAIVVQCSDGVGRSGTLCAIMSVIERVkvEHVVDVFQAVKNLRISRPG-AVETLEQYKFCYDVTLAY
.... ..| || ||||.|||.|.. ..|.. |..||...||| || ||| ||..||||.|.|.. | .
llldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllel
|
subfamily_PTPN5_RR_pd |
Subfamily PTPN5_RR |
6-241 |
2.4e-69 |
228.5 |
In-house |
28-266 (274) |
alignment |
Range on Protein: 6-241
Range on HMM: 28-266/274.0
NKIKNRYGNIVTYDHTRVVLKGPGGNrDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQP-
.. |||| .|. ...||.|. .. | |.|||| ...|.|.. | |.|.|||. .|||.|..||...|||||| | | ..||..|.||...
sqtknryktilPnensrvllesesse.dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedye
--KPYGQYTVSLCKNEAFADYTVRTFLVTSAPSneQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIIN---ESRHNTAPWIVHCSAGVGRTGAFIVIDAM
. ||. . | ||.||.... .. . .| .. | .| |||. .|. |...|.. ... . |. ...|| .||||||.||||.|| |.
iserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisia
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
.|| .|..|||. . | | || ||||..|| .||||. .
vrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
294-534 |
3.9e-69 |
228.1 |
In-house |
3-243 (245) |
alignment |
Range on Protein: 294-534
Range on HMM: 3-243/245.0
SASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQ
.|.. .| .|||..||||.|. || | ... |.. ||||||. . || . ||.||.||..|.. ||||. .... |||||....| . . ...|||..
vallpenkdknrysdilpydhtrvkls.pdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
GAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIE
. .||...|.| .|. .. .. | . .| .|.. .. ..|.. ..| ||.||| . .|| .|. ... ....... ..| ||.||||.||..|. ..|
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
RVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
... |. |....||| || |||||.|..||.|.|.. | .|
qlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
294-533 |
4.4e-69 |
228.1 |
In-house |
5-245 (249) |
alignment |
Range on Protein: 294-533
Range on HMM: 5-245/249.0
SASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQ
|.. .| .|||.|||||.|..|| |. ... .. ||||||. . |. ..||.||.||..|...||||. ... ..||||.||.| |.. .|||..
vallpenkdknrypdilpydhsrvklsi.lpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplg
GAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKS-GDKAIVVQCSDGVGRSGTLCAIMSVI
| |||...|.| ... |. .. | . .| ...... .. |.|.|.| ||.||. . ||| ... ... ... .. ..| ||.||||.||..|. ..
gsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylml
ERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
|... |. ||...||| || |||||...|||.|.|.. | .
eqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
subfamily_Sponge-PTP11_pd |
Subfamily Sponge-PTP11 |
271-536 |
1.3e-68 |
226.0 |
In-house |
19-285 (290) |
alignment |
Range on Protein: 271-536
Range on HMM: 19-285/290.0
VSGYESEFQRLSIFWLSPDVRVEsaSRACNASKNRFPDILPLDSHRVALH-LSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDL
.|....|..| . . | |. | .||| .|.. | .|. |. .| .|| .||||.. . |.|....|.||.|...|.. ||..... .
negfrnqfkmldsgesehtvtvg..ltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekv
GTIVMLNSLDEEDE-HFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGK-STPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGD
|||| . ||.. . |||......|| ....|..| . .| |..... | . ..| . ..|.||| .. .| | ... .. | |.|.
tiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgn
KAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLDS
..||| |||.||||...||.. |...| | |.|||| .|..|| .|| |.| .||.. ... | ||||
tsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
293-531 |
1.8e-68 |
225.7 |
In-house |
36-274 (314) |
alignment |
Range on Protein: 293-531
Range on HMM: 36-274/314.0
ESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPS
..| . | .|||. |||. | .|| |. ..| || .|||||.. .|. .||| || ||..|.. |||.| |.. .||||. | |. . .|||
daakkdenreknrsgdilaydrsrvfli.tidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe
QGAEeYGGIKVELQEEDDKSFFISRRFDITT--KGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKsGDKAIVVQCSDGVGRSGTLCAIMS
.. || ||||| | . .. ...| | .. .|.. . . .|| ..|.|| || . || |. ...||.. .. ||| || | ||.|| .|| .
dtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidi
VIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
|.. .. |.|||||.|||.|| ... ||| |||||.||| |
vldmieregvvdvfnavktlrsrkvnmveteeqykfiydvil
|
subfamily_Ptp69D_pd |
Subfamily Ptp69D |
265-533 |
1e-67 |
223.4 |
In-house |
15-285 (307) |
alignment |
Range on Protein: 265-533
Range on HMM: 15-285/307.0
IRPREQVSGYESEFQRLSIFwlSPDVRVESASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMV
| |. |.. |...| | . . . || |||..|| . |..|| |. . . .||||||| ..|.|.. || |.|.| || ||||.
srkrdtdfglakeyekLear..eidkstkvsekkenalknRyedikafDktRvkLkk.ingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmi
VDYDLGTIVMLNSLDEEDE-HFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKST-----PQRICHFQVTNWSDHSVPDKPLDLLPLLNDI
. .. .|||| |.| .. . ..||| . .|| | |.| .|. .| .| | .|...|.... ... .. |.| | ||. . || |.. .
aeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqv
QTSQQKSgDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
. .... ||| || ||||||.. |. |.....| |. ||.|. ||.|| |. |. ||||.|.| | |
relykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldy
|
subfamily_PTPN9_pd |
Subfamily PTPN9 |
2-241 |
1.3e-67 |
223.0 |
In-house |
38-288 (297) |
alignment |
Range on Protein: 2-241
Range on HMM: 38-288/297.0
KKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWP-D
|.. | |||| ... ||.|||||. . | ||||||.|..|. .| .||.|||.. ..|||.|||.... |||| | ..| . || .||| .
klranleknrytdvlcydetrvvlakv..dedeasdyinanfvdGyk.qkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWple
TNQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINE-------------SRHNTAPWIVHCSAGV
... . .|...|| . | ||.||.. .. . .|.| . . |. ||| |||. |...| ...|. .. . . | .||||||.
eessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGi
GRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
||||.|| .| | . .|. .||. . |. | | ..|| .||.| . ||||
GrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
2-243 |
5.7e-66 |
217.6 |
In-house |
33-269 (273) |
alignment |
Range on Protein: 2-243
Range on HMM: 33-269/273.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGnrdgrsdYINASFLQGFDG-TPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
|| ||| |||| |.. ||.||| |.. || |||||... | .|||.|||. ...|||||||. ...||.|.| |. | |||.|||.
kkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPe
TNQP--KPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRhNTAPWIVHCSAGVGRTGAFIVIDA
... | .....|.| | . ...||.. |. |.| | . . .|. ||| |||. |. .|.| ... . . ...| .||||||.||.|..|.||.
sknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidv
MLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
.| . .| .|. . || | | .|||||||.|...|.||.|
vlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
|
subfamily_Sponge-PTP10_pd |
Subfamily Sponge-PTP10 |
272-536 |
1.9e-64 |
212.4 |
In-house |
20-280 (287) |
alignment |
Range on Protein: 272-536
Range on HMM: 20-280/287.0
SGYESEFQRLSIFWLSPDVRVESASrACNASKNRFPDILPLDSHRVALHlsvdkDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGT
|.. |. | ..| . . | |||. .||. | .|| |. . |||||.| .|.|..|||....|. .|. ||... | .
egfknqftvleqvtqredevthnia.sqnkdknRltqilvpdnyrvllk.....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvta
IVMLNSLDEEDEH-FPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGK-STPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKA
|||| . |.||. .|||.. . .| ..|| .|. .. .| |..... |.| ...|.. .|.||| .. .| | .... .|.|.|. .
ivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgnts
IVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLDS
||| |||.||||...||. |...| | |.|||| .|. || .||.| | ||||| .|. |.||||
ivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleylds
|
subfamily_PTPRG_pd |
Subfamily PTPRG |
272-533 |
3.9e-64 |
211.8 |
In-house |
19-286 (563) |
alignment |
Range on Protein: 272-533
Range on HMM: 19-286/563.0
SGYESEFQRLSIFWLSPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGT
|.. ||. | | |. .|.... .| ||| .|.. |. || |. .|. |||||.. . |. .||| || ||.||. ||||. . .
igfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvai
IVMLNSLDEE-DEHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITT----KGKS--TPQRICHFQVTNWSDHSVPDKPLdllPLLNDIQTSQQK
|||. | |. .. ..|||....|.|| ..| |.||. .. .|.. | |.|. | ... ... |.| ||.||...| | |. .. |..
ivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehsl...pvLifvkkssaa
SGD--KAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
. ||| || ||||.||.... ....... |..|.||. .| .| |. |.| ||| | .|. |
nkaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdallea
|
subfamily_Sponge-PTP5_pd |
Subfamily Sponge-PTP5 |
5-258 |
4.4e-64 |
211.1 |
In-house |
32-281 (283) |
alignment |
Range on Protein: 5-258
Range on HMM: 32-281/283.0
ENKIKNRYGNIVTYDHTRVVLKGPGGnrdgrsDYINASFLQ--GFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN
||| |||. .||..| || || |||||.|. . ||||.||.|.. |||.||..|. . ||||| | |. ..|| .|||
enkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrG
QpKPYGQYTVSLCKNEAFADYTVRTFLVTSAPS-NEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLR
. ||..||.| |. . .... .|. | ... .. | . | . | ....| | | . ... .| .||||.|.|||..|| . | .
s.edyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvk
QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLRNV
.|. . |||... |. | .|. .|||.||| ..| .||| .|| |.| | .| .
daltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqst
|
subfamily_PTPRN_pd |
Subfamily PTPRN |
1-241 |
4.1e-63 |
207.8 |
In-house |
51-290 (297) |
alignment |
Range on Protein: 1-241
Range on HMM: 51-290/297.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
||...| |||. ....|||.|| || . . .|||||||.. | |||.|||. . |||||||.. . |||.|| | | . ..|..||||
akaeknvkknrskavlpydhsrvklkee..asaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpd
TNQpKPYGQYTVSLCKNEAFA-DYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
. . . |. | | | . .. || ||.| . ..| | . |.|| ||..||| | ..| ||.|. | ..| .||||.|.||||..|.|| .
eGs.evyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlv
LR-QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
| .| | .|| . | .||..|.||||. |. || |
lnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
subfamily_Urchin-PTP-1_pd |
Subfamily Urchin-PTP-1 |
288-534 |
1.3e-62 |
206.5 |
In-house |
31-277 (315) |
alignment |
Range on Protein: 288-534
Range on HMM: 31-277/315.0
PDV-RVESASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HF
||. | .| | .|||. .|||||| || | . .|..| ||||||. ... . .|.| .|.||. .. |||||.... ||||.. ..|.| .
PdiyrqrvaretinfkknryknilPldsarvklev.iddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikc
PRYWPSQGA--EEYGGIKVELQEEDDKSFFISRRFdITTKGKSTpQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSqQKSGDKAIVVQCSDGVGRSGT
.||| . | |.| ||||| . . . . |.. .| |.... ... || |.| |. |. . || |. ..... ... . ...| || ||||.|
rqywPdrkadsvefGsikvellsleadtdgvarkl.vtrksees.rtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGv
LCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
...|..|....| ...||||. ||||| || | | |.| | ||. | .|
visidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
294-533 |
2.8e-62 |
205.7 |
In-house |
4-241 (243) |
alignment |
Range on Protein: 294-533
Range on HMM: 4-241/243.0
SASRACNASKNRFPDILPLDSHRVALhlsvdkdPGADYINASFAHAYrERnaFILTQAPLEDTIAS----FWRMVVDYDLGTIVMLNSLD-EEDEHFPRY
|.. .| ||||..||||.| || | .| |||||.. . .| .|.||.||..|... ||||. ... ..||||..|. . | ..|
iallpenlsknrysdilpydhsrvkl.......egsdyinanliyvt.pr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPsqGAEEYGGIKVELQEEDDKSFFISRRFDITTKG-KSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQK-------SGDKAIVVQCSDGVGR
|| | ..||...|.| .| .. .. | . .. .. . .. ..|.. ..| ||.||| | ||| .|..... ... .... ..| || ||||
wp..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgR
SGTLCAIMSVIERVkveHvVDVFQAVKNLRISRPG-AVETLEQYKFCYDVTLAY
.|||.|. ..... . ||...||| || ||| ||.|..||.|.|.. | .
tGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
6-241 |
4.6e-62 |
204.5 |
In-house |
20-262 (270) |
alignment |
Range on Protein: 6-241
Range on HMM: 20-262/270.0
NKIKNRYGNIVTYDHTRVVLkgPGGNRDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQP-
.| ||| .|. .|||.| . . | .. |||| ...|||| .||||||.||.. . .||.|.|.|. . |||.||| | ..|| .||| ..
gkklnRyadiLPsPatRvrl..eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
--KPYGQYTVSLCKNEAFADYTVRTFLVTsAPSNEQRFIyQYHFTVWPDKGVPQYAT------AVLRFRKKI---INESRHNTaPWIVHCSAGVGRTGAF
.|. .| ...| | .. .. ..|.| . .... |||.|||. . .|. ... .| .... |..||||||||||| .
vkledgkikvlalseekeegyiltrlrle.ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkae.PllvHcsaGvgRtGtl
IVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
|..| ..| .|.| ||. . ... | ||...||. .|| |...||.|
ialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
subfamily_PTPN23_pd |
Subfamily PTPN23 |
6-242 |
1.2e-61 |
203.0 |
In-house |
43-279 (288) |
alignment |
Range on Protein: 6-242
Range on HMM: 43-279/288.0
NKIKNRYGNIVTYDHTRVVLKgpggnrDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD-TNQP
. |||. .|. |||.||.|. ... |||||||... . ..||.|.| ... |||.||.... ||||||. | |.|...||| ....
yseknrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkget
KPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIIN----ESRHNTAPWIVHCSAGVGRTGAFIVIDAML
. .|...|.| ... . |.. .. .... . . ..| ||. |||. .|.| ... . . |. .| .|||||||||||.| .. | .
vkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaav
RQAKE-KKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
|. .. . ..|| . |. | .| .|||.|.|. | |||||
relekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
subfamily_Sponge-PTP6_pd |
Subfamily Sponge-PTP6 |
6-255 |
1.8e-61 |
203.0 |
In-house |
48-291 (439) |
alignment |
Range on Protein: 6-255
Range on HMM: 48-291/439.0
NKIKNRYGNIVTYDHTRVVLKGPGGNrdGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKekchkYWPDTNQpK
.. |||| .....|||||.|. | | |||| ...|. ..| |||.||| . ..||||..|...... ||||| |.| | ||| ..
dqtknrykdvgafdhtrvtlqeipgv..phshyinanyikGyy.ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdae.v
PYGQYTVSLCKNEAFADYTVRTFLVTSA--PSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKI-INESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQ
||. .| .| . .|..| | | .. .| . |.|.. |||| || |. || | . | . .... | .|||||||||||. | .| | |
cygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeq
AKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNL
| .. ||| |. | .| .|||. |||||. |||| .| | . .. ..
lklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidef
|
subfamily_Urchin-PTP-4_pd |
Subfamily Urchin-PTP-4 |
1-256 |
2.9e-61 |
202.0 |
In-house |
40-249 (392) |
alignment |
Range on Protein: 1-256
Range on HMM: 40-249/392.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINASFLQGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSkekchkywpd
|.|. |. ||||.||. || .||.|. . |||.|||....|| | |||.||| | ||||.||.||. . |.|.| | ||
aqkeinlkknryknilpydsarvklevi..ddipdsdylnasyipsfdn.ekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd..........
tnqpkpygqytvslckneafadytvrtflvtsaPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAML
...| . |.||| ||||.||......|.| |.. . . | | |.|||||||||| | ||...
.................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvv
RQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTDIQAPNLR
.||. ..||..|.| | || |||||.|| ||. |||| |. | | .
ahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhft
|
subfamily_PTPN1_pd |
Subfamily PTPN1 |
1-245 |
3.6e-61 |
201.4 |
In-house |
27-273 (290) |
alignment |
Range on Protein: 1-245
Range on HMM: 27-273/290.0
AKKPENKIKNRYGNIVTYDHTRVVLKgpggnrDGRSDYINASFLQgFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD
||.|||. .||| .. |||.|..|. .. ||||||... .. ..|| .|||. .| ||||||.... .||| ..| .. ||..|||
aklpenrnlnryrdvspydhsrikle......radndyinaslve.leeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPq
TNQP----KPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINES--RHNTAPWIVHCSAGVGRTGAFI
.. ...| | ..| ||||.. .. ..| | |...|.| ||| |||. .| |.| |. . .. | ..|||||.||.|.|.
geeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfc
VIDAMLRQAKEKKV---VDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVC
..|..| . ..|. ||| . . . | | ..||.|| | . |.|| .
lvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakv
|
subfamily_Urchin-PTP-5_pd |
Subfamily Urchin-PTP-5 |
295-535 |
4.4e-61 |
201.6 |
In-house |
46-285 (297) |
alignment |
Range on Protein: 295-535
Range on HMM: 46-285/297.0
ASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRErnAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWPSQGA
| . | .|.|. .||| || || |. .|..|| .||.|||| ..... .| || | ..|.| ||.||.|.. |||||| ..|.|.. |||. .|
aekkvnfeksRYkniLPydssRvkLa.ivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdkgv
EEYGGIKVELQEEDDKSFFISRRFDITtKGK-STPQRICHFQVTNWSDHSVPD--KPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVI
..| . |.|. .... || | ...| ||| . . . .| ..| |..|. . || |..... . .. . ..| |. |||| | |..| ||.
ttfGdvsvvllsvsereGfikrelevt.kgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvv
ERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
..| |. ||.|. || || .|| | | ||||| | . | .|
aeakrekevdifglvkklrqerpylvqtkeqykfvyvavleall
|
subfamily_PTPRB_pd |
Subfamily PTPRB |
272-534 |
9.3e-61 |
200.4 |
In-house |
25-285 (293) |
alignment |
Range on Protein: 272-534
Range on HMM: 25-285/293.0
SGYESEFQRLSIfwLSPDVRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGT
.. |...|. . | |..|..|.|..|||. .||| | || |. ......|.|||||.. . |. .. || || || .|. ||||| . .
lrfseeyeelka..vgkdqavkaaelavnraknrytnilpydhsrvkLa.alkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssi
IVMLNSLDEEDE-HFPRYWPSQ-GAEEYGGIKVELQEEDDKSFFISRRFDITTkgKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQ-QKSGDK
|||| | |. . .|||.. . || |||.|..|.... .. | . |. ... ... ... | |.|| ||.|. || ... ..... ... ..
ivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskr
AIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
||| || ||||.||. |. ...... | .||.| | .|| .| | | .|| | ... |..|
PivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldll
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
248-535 |
3e-59 |
195.5 |
In-house |
2-298 (306) |
alignment |
Range on Protein: 248-535
Range on HMM: 2-298/306.0
TDIQAPNLRNVMTKLEKIRPREQVSGYESEFQRLSIFWLSPDVRVESASRACNASKNRFPDILPLDSHRVALHlsVDKDPGADYINASFAH--AYRERNA
|.. | .... ...||| . . . .|.| ||..|. . . . .... |..|||. ||| | || |. .. ||.|||||.. . . ....
tsllakeieqrvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk..epsvpgsdyinanyikkevkgsdks
FILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQGA-EEYGGIKVELQEEDDKSFFISRRFDIT-TKGKSTPQRICHFQVTNWSDH
.| || ||.|.. |||||.. . |||. | |. ||||.. . |||| |.|. .|.... .| |.. .. .| |.. ... ... ..| ||
yiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdh
SVPDKPLDLLPLLNDIQTSQQKSG---DKAIVVQCSDGVGRSGTLCAI---MSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
.|| .| .| .|.|... |... .||| ||.|.|| ||. | ...||. ... .|. ..|| .| | | | | .|||| | . .|..
gvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
292-531 |
3.9e-59 |
195.1 |
In-house |
41-276 (315) |
alignment |
Range on Protein: 292-531
Range on HMM: 41-276/315.0
VESASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHFPR-YWP
.. | . | |||. .|.. | || | | ...||..||.||.| | .. .| .|.|. .. |||.| ..|.|.||||..| |.... |||
ldvakkienkqknryiniiaydksrvqlpl.lendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywp
SQgAEEYGGIKVELQEEDDKSFFISRRFDITTkgKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGdKAIVVQCSDGVGRSGTLCAIMSV
. || | | ...|. .. . | . .. .. . . ...| | | || . |. | .. ...| |||| ||.||||.||.... .|
dk.kviyGkitvtrkseevnteytvrtlsvvf..gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldav
IERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
......|...||.......| | ..|...|||.| ||. |
ldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydall
|
subfamily_Sponge-PTP5_pd |
Subfamily Sponge-PTP5 |
278-531 |
1e-58 |
193.5 |
In-house |
15-263 (283) |
alignment |
Range on Protein: 278-531
Range on HMM: 15-263/283.0
FQRLSIfwlsPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDkdpgaDYINASFAH---AYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVM
..|||. || .. || | |||. .|.| | .|| |. |||||.| |.. . .| .|.||..|. ||.|| | . .|||
lkrlsv....pdldadiasadenkrknrnqeivpadqwrvelksesr.....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivm
LNSLDEED-EHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTK--GKSTPQrICHFQVTNWSDHsVPDKPLDLLPLLNDIQTSQQKSGDKAIV
| | |. .. .|||..|.|.|| | |..| . || . . . .. ||| ..|.|| .| . .. ... | .| ... |..| . ||
ltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstll.lahyqvidWley.geqaiinslvkfnkvislqteskkgPiv
VQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
| || |.||.....|... .. .. | |||||. ||..| |..|| ||.|||. ... |
vhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvl
|
subfamily_Urchin-PTPRA_pd |
Subfamily Urchin-PTPRA |
274-530 |
1.5e-58 |
193.6 |
In-house |
36-287 (319) |
alignment |
Range on Protein: 274-530
Range on HMM: 36-287/319.0
YESEFQRLSIFWlSPDVRVESASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIV
.| ||.|.. . . | | |||. .||. | .| |. .. ..||||||| |. .. .| .| ||..|.| ||||. .|. |||
levefrracklg.vnladqtfanldqnkdknriinilafdknvvkler.liGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstiv
MLNsldeeDEHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQR-ICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQ-KSGDKAIV
.| .. .||| .. .... ||... .. . .. | .... .|| . .| | | | |. ||| | ||. |.. .. .. . . . ||
llt.....kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhraniv
VQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVT
| || ||||.|. .. ...|.| |. |||.. |..|| |. |. | ||||.|
vhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysal
|
subfamily_CG7180_pd |
Subfamily CG7180 |
294-533 |
2.5e-58 |
192.1 |
In-house |
36-289 (296) |
alignment |
Range on Protein: 294-533
Range on HMM: 36-289/296.0
SASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWPSQG
. |. | ||| ....| | || |. ..| . |||||.. .. ...| |.|| ..|. .|||.| | . ..|.| . . .| ||| ..
gglrkenreknrdvkvvPyDynRvvLe.kldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnks
AEEYGGIKVELQEEDDKSFFISRRFDITTK---------GKSTPQRI-CHFQVTNWSD-HSVPDKPLDLLPLLNDIQTSQQKS----GDKAIVVQCSDGV
|.|| | ||. ||. . . .| | .| | . ....|| ..||.| | ..|| |. |.. ... ..| . .|| .|||.
keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGa
GRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
.||| .|| .| |. |. ||||.||| ||.|||. ||. |.||..||| | .
sRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
subfamily_Urchin-PTP-3_pd |
Subfamily Urchin-PTP-3 |
293-532 |
2.6e-58 |
192.7 |
In-house |
41-286 (325) |
alignment |
Range on Protein: 293-532
Range on HMM: 41-286/325.0
ESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWPSQ
. | . | .||||.....|| || | . ..|| .||||||. . ..... |. .|||| .|| .||.|.|. .|.|| ||..... ||| .
kvamkpenkaknrfknvvaldksrvvle.tkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdrcavywpke
--GAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQ-----KSGDKAIVVQCSDGVGRSGTLC
. ..||..|.|. .. | .. |..|. | . . ||. | | |. .| |...|. ... .. . |.| ||.||||.|..
mgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfi
AIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLA
.. |....| | ||.|. ||.|| || ||| .|| ..|.
slysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealve
|
subfamily_PTPN14_pd |
Subfamily PTPN14 |
1-242 |
3.7e-58 |
191.9 |
In-house |
44-295 (300) |
alignment |
Range on Protein: 1-242
Range on HMM: 44-295/300.0
AKKPENKIKNRYGNIVTYDHTRVVLKGpggNRDGRSDYINASFLQGF-DGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWP
|| |||. |||. ... |...|| |. ... ...||||| .. |. ..||.||||.| . |||||||.. ..||||| .|. |||..||.|
aklpenaeknrfkdvlPyednrvelsp...tkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfP
DT---NQPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKII------N---ESRHNTAPWIVHCSAGV
.. .. .|.. |. .| .. ... . ||.|.| .. .| |||.|||. . | . ... | ||... | .|||||||
kleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGv
GRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
|||| |. | .. . ...|| . .. | | .||| || |.......
GrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvliky
|
subfamily_Urchin-PTP-6_pd |
Subfamily Urchin-PTP-6 |
296-534 |
5.4e-58 |
191.3 |
In-house |
39-276 (515) |
alignment |
Range on Protein: 296-534
Range on HMM: 39-276/515.0
SRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEH-FPRYWPSQGA
| .|||. .|||.|| || | . .. .| ||.|||. ... .|.| .|.|.. .. |||.|.... ||.|.. | |.| .||| . .
qeeinfkknryknilPydsvrvklev.indnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpg
E--EYGGIKVELQEEDDKSFFISRRFDITTKGKstPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGdKAIVVQCSDGVGRSGTLCAIMSVIE
. ..| ||||| . . | |.. .. . . . |. |.| |. || . || |. ........ .... || |||| | ...|.||.
dsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvva
RVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
..| ..||||. |.|.| || | | ||| | |.. | .|
hakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
subfamily_Urchin-PTP-8_pd |
Subfamily Urchin-PTP-8 |
298-530 |
8.3e-58 |
191.1 |
In-house |
23-251 (284) |
alignment |
Range on Protein: 298-530
Range on HMM: 23-251/284.0
ACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNsldeeDEHFPRYWPSQGAEEY
| |||. .||. | .| |. .. ..||||||| |. .. .| || ||..|.| ||||. .|. |||.| ... .||| .. ...
dqnkdknrighilafdknvvkler.liGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.....kdkcsqywplkivike
GGIKVELQEEDDKSFFISRRFDITTKGKSTPQR-ICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQ-KSGDKAIVVQCSDGVGRSGTLCAIMSVIERVK
. ||... .. . .. | .... .|| . .| | | | |. ||| | ||. |.. .. .. . . . ||| || ||||.|. .. ...|.|
erfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmk
VEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVT
|. |||.. |..|| |. |. | ||||.|
eekqvdvynfvrdlrqqrntlvqdlvqykfiysal
|
subfamily_Choan-PTP-1_pd |
Subfamily Choan-PTP-1 |
266-535 |
4.3e-57 |
188.4 |
In-house |
9-277 (281) |
alignment |
Range on Protein: 266-535
Range on HMM: 9-277/281.0
RPREQVSGYESEFQRLSIfwLSPDVRVESASRACNASKNRFPDILPLDSHRVALHLSvDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVV
. ... .|. .|.. |. . | ... . | |||. .| | || .. . ... .|||||.| .|.. ...| ||.|. .....||.||.
lsqndnaGfieeyeklaa..igvdntataskadenvlknrYsnivaYDatrvkvtpn.eenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvw
DYDLGTIVMLN-SLDEEDEHFPRYWPSQG-AEEYGGIKVELQEEDDKSFFISRRFDItTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQ
... .|||. .... . |||| . . .|| ..|. ..| .|. .|.|.| . .. .. .... ... |.| || ||... .|| .... ..
eqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlklte
KSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVE-HVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
|. . ..|. || ||||.|| |. ....|. | . .|| . |..|| .| | |. ||.| | . | .||
kktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
subfamily_CG7180_pd |
Subfamily CG7180 |
3-247 |
8.4e-57 |
187.1 |
In-house |
39-294 (296) |
alignment |
Range on Protein: 3-247
Range on HMM: 39-294/296.0
KPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgrSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKeKCHKYWPDTN
. ||. |||. ..| ||..||||. .|. . ||||||.. ..| .|.|| ..|.. . |.||..|..| .| .|.|| . .| ....||| .
rkenreknrdvkvvPyDynRvvLekldGeek..sdYinavyvdsfl.kkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks
qPKPYGQYTVSLCKNEAFADYTVRTFLVTSA----------PSNEQRFIYQYHFTVWPD-KGVPQYATAVLRFRKKIIN---ES--RHNTAPWIVHCSAG
. ||. | . ... .|. . ||| .| . |.| . ....|.|. . || ..|.. .|... . . ...| .|..| |
.keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdG
VGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGS
..|.|... ||| | ...... ||....|. | .||..|.....| .| .|||..|.
asRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
289-532 |
2.4e-56 |
185.7 |
In-house |
29-275 (290) |
alignment |
Range on Protein: 289-532
Range on HMM: 29-275/290.0
DVRVESASRACNASKNRFPDILPLDSHRVALHLSVDKDpGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPR
.. |.... | |||. |||| | || |. ... | |||||.| . .. ..| .|.|| .|. ||||. .... .||. . | . . |
vysteagekeenvkknrykDilPydksrvelskieeee.gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
YWPSQGAEE--YGGIKVELQEEDDKS-FFISRRFDITTKgkSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQkSGDKAIVVQCSDGVGRSGTL
|||..| || .| ..|.|.||. . |. | . .... .. ... |. |.| || || .. .|| |...... |. | |. .|| || |||| ||.
YWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGti
CAIMSVIERVKVEHV---VDVFQAVKNLRISRPGAVETLEQYKFCYDVTLA
.|| | | .| |.. .|||. | .|| |. .| | |||.. | .
iaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
|
subfamily_PTPN23_pd |
Subfamily PTPN23 |
272-533 |
3.4e-56 |
185.2 |
In-house |
15-279 (288) |
alignment |
Range on Protein: 272-533
Range on HMM: 15-279/288.0
SGYESEFQRLSIFWLSpDVRVES-ASRACNASKNRFPDILPLDSHRVALHlsVDKDpgaDYINASFAHAYRE-RNAFILTQAPLEDTIASFWRMVVDYDL
.. . .|. | . | | | ....|||. |||| |. || |. || ||||||| . || |||||. |.. ||.||..
taldkkfkeleqkqdk.earkrsiaiaklyseknrsrdilPyDhnRvklr..gskD...DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqks
GTIVMLNSLDEEDEH-FPRYWPSQG--AEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQT---SQQ
.|||| | .| ... ||||.. ....| ..| |... . . .. | . ..|..... . ..| |.|.|... ||. | .|| .|. ... ..|
sviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavq
KSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEH-VVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
. .. .||.|| ||||.|... ...... ..... ..|. | |. || | |.. ||.||.|.. | .
rksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
subfamily_Sponge-PTP9_pd |
Subfamily Sponge-PTP9 |
297-534 |
3.2e-55 |
181.9 |
In-house |
37-293 (301) |
alignment |
Range on Protein: 297-534
Range on HMM: 37-293/301.0
RACNASKNRFPDILPLDSHRVALHLSVDKD-PGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQ--
. |. ||| .| ..| .|. |. . | .|||||. ..|.|...|| .|.|.. |.. |||..... .|||. |.|. .. .|||.
seenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnsea
GAEEYGGIKVELQEEDDKSFFISRRFD-----------------ITTKGksTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIVVQCS
||.| ..|.|..| |. |.. .... ... . .|||.| .. | | | ..|. ||| | .|| ||
eseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCS
DGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
|.|.|||. |.. .| .| | |||||| .| .| |.|||| ||||| . ||| ||
dtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmyl
|
subfamily_Sponge-PTP9_pd |
Subfamily Sponge-PTP9 |
4-249 |
3.6e-55 |
181.8 |
In-house |
38-299 (301) |
alignment |
Range on Protein: 4-249
Range on HMM: 38-299/301.0
PENKIKNRYGNIVTYDHTRVVLKGPGGNRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN-
||| ||. ||..||. |..|| . .|||||...|. ||.||||||.. |||...|||. . |||.|.| ||.|.||..|||...
eenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgys.ekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnsea
QPKPYGQYTVSLCKNEAFADYTVRTFLVTSA-PSN--------------EQRFIYQYHFTVWPDKGV-PQYATAVLRFRKKIINESRHNTAPWIVHCSAG
. . .|. || | .. .. |...| . |. || . . . |.. | ||. || ....| . . |. . . . .| .||||..
eseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdt
VGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCGSTD
|.|.| .. .. | |.| |||... ..| | .| .|.| .||..|. .. . | . ||
VsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
subfamily_PTPN5_RR_pd |
Subfamily PTPN5_RR |
298-534 |
4.7e-54 |
178.3 |
In-house |
26-268 (274) |
alignment |
Range on Protein: 298-534
Range on HMM: 26-268/274.0
ACNASKNRFPDILPLDSHRVALHLSVDKDPGADYINASFAHAYRE-RNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWPSQG--
. ...|||. .||| . || |. . .|. ..|||| . . |.| .|.. || || |.| ||||. . |||| | |..| .|.| .
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
--AEEYGGIKVELQEEDDKSFFISRRFDITTKGKstPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDK--AIVVQCSDGVGRSGTLCAIMS
.|.||..... .. .. . |.. . . .... |. |.| || .||.. || |......|.... | ..|| || |.|| | ||
eiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
VIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
. ... |.||||.. | |||. | | |.| |||.. . . ||
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl
|
subfamily_PTPN9_pd |
Subfamily PTPN9 |
289-533 |
6.9e-54 |
177.9 |
In-house |
31-289 (297) |
alignment |
Range on Protein: 289-533
Range on HMM: 31-289/297.0
DVRVESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPR
... . .| .|||. |.| .|. || | .||.|. .|||||.| |....||| || ||. |. ||||| . . .||| . |. .
eGtflasklranleknrytdvlcydetrvvla.kvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgq
YWP--SQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKS------------GDKAIVVQ
||| .. ..|.| ..|. | . .. . | . |. .. ... |||.. | |. ||. .|| .|. .. | .. . |||
yWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvh
CSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
|| |.||.||.... ..|.. . .|||...|| || | .. | |||.||| | |
csaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
subfamily_Choan-PTP-3_pd |
Subfamily Choan-PTP-3 |
6-240 |
3.4e-53 |
175.3 |
In-house |
38-274 (287) |
alignment |
Range on Protein: 6-240
Range on HMM: 38-274/287.0
NKIKNRYGNIVTYDHTRVVLKGPGgnrDGRSDYINASFLQGFDGtPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPK
. ||||.... .|.|||.| | . |||||| .. .. ...||||||. . |||..|...| ......| .| .. ||.||||. ..|
avkknryadvlPiddtrvllsaeg...elGsdyinanyvasytd.deafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPm
PYGQYTVSLCKN-EAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKI---INE--SRHNTAPWIVHCSAGVGRTGAFIVIDAM
| |.| | . .|.||.. . . ..| | . |... ||||... | ...|| .. |. . .. | .||...|.||.| .. . ..
rvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvl
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVL
... .. ||. . | | | .||. |. .. |.
vsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
36-246 |
6e-53 |
175.5 |
In-house |
4-227 (272) |
alignment |
Range on Protein: 36-246
Range on HMM: 4-227/272.0
SDYINASFLQGFdGT---PKKYIAAQGPVEPSCDDFWQMvWQERCSVIVMLTGLIEGSKEKCHKYWP-----------DTNQPKPYGQYTVSLCKNEAFA
|.||||... |. | |.......|| . ...|||.. .......||.|... | ..||..||| |. .. ||...| | . | .
sgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DYTVRTFLVTSA-PSNEQRFIYQYHFTVWPDKGVPQYAtaVLRFRKKIINesrhnTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKVVD--------IY
||..|..|.| . .| | ....|.| ||| |||| | .|.. . . . | .||||||..||| ..... .|.. . .|| ..
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle
NYVRATRGDRPNMVQTKDQYVFIHRAVLEAlVCG
..|. | ||..||| .||.|...|.||. ...
eaveelraqrpgavqteeqylflyeallel.lrs
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
277-535 |
7.7e-50 |
164.7 |
In-house |
16-270 (273) |
alignment |
Range on Protein: 277-535
Range on HMM: 16-270/273.0
EFQRLSifWLSPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDkdpgadYINASFAHAYR--ERNAFILTQAPLEDTIASFWRMVVDYDLGTIVM
||. | | | ..|.. .. | .|||. ..|| | || | . |||||. .. .. .|..| || .|.. ||.|| . . |.|
efkelr..elkpldtcevgkkkenkdknryrnvlPydetrvklgdegg......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviam
LNSlDEEDEH--FPRYWPSQGAEE---YGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQksGDKA
. . . |... ||||.. .. .. ..||| . ... | |.. .. . . ... |.. ..| ||.|| ....|| .. ... |.
vtl.ekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagP
IVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
||| || |.|||||| .| |.. .. .. .|| . |..|| | | | | .|| |.| ..| |
ivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
subfamily_PTPN3_pd |
Subfamily PTPN3 |
285-532 |
2.3e-49 |
162.8 |
In-house |
26-273 (280) |
alignment |
Range on Protein: 285-532
Range on HMM: 26-273/280.0
WLSPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDkdpgaDYINASFAH----AYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDE
|.. .. | .. |.||||. |||| |. || |. | |||||.. . | .| || ||..| . ||.|| . . .|||| .| |
rkkpglaisaarkpenlsknryrdilpydatrvklkeset.....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlve
ED-EHFPRYWPSQGA-EEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQkSGDKAIVVQCSDGV
. .|||... |||...|....|| .. .. | . .. | .. ..| ..| ..|.||.|||.. |.| ... ... .. . .. .|| || |.
rGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrs.gkeePvvvhCsaGi
GRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLA
||.| | .. . . .. | . . |...| | |.| .|||| . .|.
grtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
297-534 |
2.6e-49 |
162.6 |
In-house |
17-264 (270) |
alignment |
Range on Protein: 297-534
Range on HMM: 17-264/270.0
RACNASKNRFPDILPLDSHRVALhLSVDKDPGADYINASFAH-AYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQGA
| .. ||. |||| || | ....|. . |||| . . . |....| ...||. |. |||||... .|||. | |. .. ||||..
aargkklnRyadiLPsPatRvrl.eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk
E----EYGGIKVELQEEDDKSFFISRRFDITTKGKStpQRICHFQVTNWSDHSVPDKPL------DLLPLLNDIQTSQQKSGD-KAIVVQCSDGVGRSGT
| |.| ||| ..| ....| .| ...||.. .|..||. ..| ||.|| .. .|| .|.... |... . . ..| ||.||||.||
ekvkledgkikvlalseekeegyiltrlrleekgee..rrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGt
LCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
| |. ... .. .. ||| . ...|| |. |.. |||.| | . . |
lialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
6-248 |
1.8e-47 |
156.6 |
In-house |
1-176 (182) |
alignment |
Range on Protein: 6-248
Range on HMM: 1-176/182.0
NKIKNRYGNIVTYDHTRvvlkgpggnrdgRSDYINASFLQGFDGTPKkYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTgliegskekCHKYWPdtnqpk
|. |||| .|. |||.| .|||||... | . . .||.||| .. ||..|........||.|| .. |||
nldknrysdilpydhsr............dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywp......
pygqytvslckneafadytvrtflvtsapSNEQRFIYQYHFTVWPDKGVPQyATAVLRFRKKIINesrhNTAPWIVHCSAGVGRTGAFIVIDAMLRQakE
....| ..||... ||| ||| .|.| ..... . | .|||||||||||...... |... .
.............................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl..g
KKVVDIYNYVRATRgdrPNMVQTKDQYVFIHRAVLEALVCGST
. .....|| | |.||.| .||.|...|.|| | .. |
vsleeavklvrsrR...pgmvitpnqyfflqlallellllkkt
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
8-241 |
2.3e-47 |
156.0 |
In-house |
58-281 (290) |
alignment |
Range on Protein: 8-241
Range on HMM: 58-281/290.0
IKNRYGNIVTYDHTRVVLKGpGgnrdGRSDYINASFLQGfdgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN-QPKP
|||| ..| | |||.|| | . ||. | ...| . .| .||... . |.|.|| ||. ..|||| ||| | ||..|.|... .
kknrykdvvcndktrvilkd.G....ydGdyvhanyvkG...lkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevlt
YGQYTVsLCKNEAFAD--YTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIinesRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAK
.|..|| || .| | .|. | | . .. .. |||| |.. . |.|| . . |. . | .||||||.||||.|. |.. |.
fGeitv.lcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlril....rkasGpvvvhcsaGiGrtGtfvaievglqill
EKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
. | .|. . ||| | | | || ||. . ...|.
dGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
subfamily_Sponge-PTP1_pd |
Subfamily Sponge-PTP1 |
294-530 |
1.8e-45 |
150.0 |
In-house |
26-255 (267) |
alignment |
Range on Protein: 294-530
Range on HMM: 26-255/267.0
SASR-ACNASKNRFPDILPLDSHRVALHLSVDKdpgadYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDehFPRYWPSQ
| | |. .||. | || | || | . . |||||. ..|. .||||.|| ||. ||. |. .. |... .||.| ... ...|| .
sqsiaeknqernrlddnlpyddtrvilrtkeee.....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn..irlfwPPk
--GAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTpQRICHFQVTNWSDhSVPDKPLdLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSV
|..| . || | .. . ... | .|. . . . .| . .|| | ||. . | . |.. .||.||||||||||. | |
mgqakkyqdltvehslekeendyqiitlelkfknesa.hnvtlyyykkwni.ntnnkpy.lkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsq
IERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVT
.||.| | |.|.|. ....| |.| |.|.|.| .....
leraktegvsdifdflrkirsqriglvdtkeryiyihell
|
subfamily_PTPN1_pd |
Subfamily PTPN1 |
289-528 |
3.1e-45 |
149.1 |
In-house |
21-265 (290) |
alignment |
Range on Protein: 289-528
Range on HMM: 21-265/290.0
DVRVESASRACNASKNRFPDILPLDSHRVALHLSVDkdpgaDYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPR
|.....| . | ..||. |. | | |. |. . ||||||. .. . . .|||| || .|.. ||.|| . . ..|||| . |.. .
dfptreaklpenrnlnryrdvspydhsrikleradn.....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaq
YWPSQGA---E--EYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDK-AIVVQCSDGVGRS
|||.. | .||.| .|..||... | .... . . | || | |.| .||. | .| .| ... | | |. |. || |.|||
ywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrs
GTLCAIMSVIERV---KVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYD
||.| . ... .. . ||. . . .|| | | . | .| .| |
GtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsyl
|
subfamily_Cele-PTP-6_pd |
Subfamily Cele-PTP-6 |
6-242 |
9.9e-45 |
147.8 |
In-house |
41-276 (307) |
alignment |
Range on Protein: 6-242
Range on HMM: 41-276/307.0
NKIKNRYGNIVTYDHTRVVLKGPGGNrdgrSDYINASFLqGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT-NQP
| |||| .. |..|.|.| .| |||| | .| | |||.|.|||| | . .|| |. ||. ..|| .|| .| ||..||| |
ntdknryqdvkcqdkgrivvkfdgla....sdyihanyl.giaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqk
KPYGQY--TVSLC----KNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLrfrkKIINESRHNTAPWIVHCSAGVGRTGAFIVIDA
. .|. |.|. |. | . . . ... | | .. .. |||.|||| . . ... | .| | .|||||||||.|. . |
lvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltai....nlleavrydtnpvvvhcsaGvGrsGtivaisl
MLR-QAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
. . . |. . |. | .|. .||. ||...|| .||
vqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
36-236 |
6.1e-44 |
145.1 |
In-house |
2-163 (174) |
alignment |
Range on Protein: 36-236
Range on HMM: 2-163/174.0
SDYINASFLQGFDGTPkKYIAAQGPVEpscddFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDtnqpkpygqytvslckneafadytvrtflvtsAPS
|||||||.| .. || ..|| ||| . ||.|.........|||. ..| ..||. |||. ..
sdyinaspldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lre
NEQRFIYQYHFTVWPDKGVPQYATaVLRFRKKIINESRH-NTAPWIVHCSAGVGRTGAFIVIDAMLRQAKeKKVVDIYNYVRATRGDRPNMVQTKDQYVF
. |...||... ||| ||| .. .|.| | . . . . | .|||||||||||...... |||. . ..||....||. | ||.|||| .|| |
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
IH
..
ly
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
2-243 |
4.7e-43 |
143.5 |
In-house |
42-280 (314) |
alignment |
Range on Protein: 2-243
Range on HMM: 42-280/314.0
KKPENKIKNRYGNIVTYDhTRVVLkgPGGNRDGrSDYINASFLQGFdgtpKKYIAAQGPVEPSCDDF----------WQMV--WQERCSVIVM-------
....|. |||| .|. .| .||.| || . .| |||||||.. || .|.||.||| | ..|| |.|| .. .. .|||
dlflnrdknryldilpad.nrvil..pglpvsg.sdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevla
--------------LTGLIEGSKEKCHKYWPDTNqpkpygqytvslckneafadytvrtfLVTSAPSNEQRFIYQYHFTVWPDKGVPqYATAVLRFRKKI
|..| .. | . ..... . .. |. .| ...|. . .|| ..| ...| . |
delsrLdaAlgKtpllildgngneptaadlellk..........................eelydpelferlgikylripvpDgsap.lledfdeflefi
INEsrHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEkKVVDIYNYVRATRG--DRPNMVQTKDQYVFIHRAVLEAL
. .. | .|||.||.|||| |.|.. .... . . .....||..| .|..... .||.||..|.||.|
eea..dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRpinpnpgfieqleqyefilealleyl
|
subfamily_PTPN14_pd |
Subfamily PTPN14 |
288-535 |
9.2e-43 |
141.3 |
In-house |
37-297 (300) |
alignment |
Range on Protein: 288-535
Range on HMM: 37-297/300.0
PDVRVESASRACNASKNRFPDILPLDSHRVALHLSvdKDPGADYINASFAHAY--RERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEH
| ...|. ||.||||.|.|| . || | . |. .||||| .. .. .| .|.||| |. ||.|| . .. |||| . |. |.
edallstaklpenaeknrfkdvlPyednrvelspt..kenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkek
FPRYWPSQG----AEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKA--------IVV
.|.|... |.| || . .| . .| . . . . . . |.| |.|.|| ||. . . | |...| ..|. .. ..|
sfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlv
QCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
||.||||.| | .|. .. ....|. .... || | |.|| |||| |.| . ||.
hCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
subfamily_Urchin-PTP-4_pd |
Subfamily Urchin-PTP-4 |
288-531 |
9.7e-43 |
141.0 |
In-house |
32-233 (392) |
alignment |
Range on Protein: 288-531
Range on HMM: 32-233/392.0
PDVR-VESASRACNASKNRFPDILPLDSHRVALHLsVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDehfp
||. .| . | |||. .|||.|| || | . .| | ||.|||. ... .|.| .|.| .. ||||| . . ||.|.. |.| |
pdiypqtvaqkeinlkknryknilpydsarvklev.iddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd....
rywpsqgaeeyggikvelqeeddksffisrrfdittKGKSTpQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQqKSGDKAIVVQCSDGVGRSGTLCA
||... . .. |..|.| |. || . || ....... . . ....|| ||||.| . .
....................................kgdda.rtvaqfhftewPdkdvpkhtssllkfikevkadf.Gqythpliihcsagvgrtgvvis
IMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
| ||. . | ..||||. | |.| || |.| ||| | | |
idsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavl
|
subfamily_Sponge-PTP1_pd |
Subfamily Sponge-PTP1 |
5-241 |
2.2e-42 |
139.9 |
In-house |
32-257 (267) |
alignment |
Range on Protein: 5-241
Range on HMM: 32-257/267.0
ENKIKNRYGNIVTYDHTRVVLkgpggnRDGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGskeKCHKYWPDT-NQ
.|. .||. . . ||.|||.| |. .|||||...|. | ...|. |.|.. . ||.... .....|||.|| .. . ...|| |
knqernrlddnlpyddtrvil......rtkeeeyinasyvegyk.tknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirlfwPPkmgq
PKPYGQYTVSLCKNEAFADYTVRTFLVTSApSNEQRFIYQYHFTVWPDKGV-PQYATAVLRFRKKiiNESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQ
| | . || . .. || . |. . . . . |.. | . | .. | |. | .|.||.||||.|.|.|||..|..
akkyqdltvehslekeendyqiitlelkfk.nesahnvtlyyykkwnintnnkpylkplfgilak..nqlengnrPlvvacsdGvGrsGtflvidsqler
AKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
||. |.||....| | |. .|.||..|..||. . |
aktegvsdifdflrkirsqriglvdtkeryiyihellae
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
300-533 |
5.1e-42 |
138.9 |
In-house |
1-170 (182) |
alignment |
Range on Protein: 300-533
Range on HMM: 1-170/182.0
NASKNRFPDILPLDSHRvalhlsvdkdpGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNsldeedehFPRYWPsqgaeeygg
| .|||..|||| | | . |||||.. .. . ||.||.|| .|.|.|.||. ... .|||.|. ..|||
nldknrysdilpydhsr...........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt........eelywp.........
ikvelqeeddkS-FfisrrfdittkgkstPQRICHFQVTNWSDHSVPDkPLDLLPLLNDIQTsqqksGDKAIVVQCSDGVGRSGTLCAIMSVIERvkveH
. . .. ..... ..| ||.||| . .|| ...... .....| || ||||.|||.|. .... .
...........ell...............erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g
vVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
|....||| .| |||.|.|..|| |.... | .
.vsleeavklvrsrRpgmvitpnqyfflqlallel
|
subfamily_Cele-PTP-18_pd |
Subfamily Cele-PTP-18 |
2-241 |
6.4e-42 |
138.3 |
In-house |
44-285 (305) |
alignment |
Range on Protein: 2-241
Range on HMM: 44-285/305.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGnrdgrSDYINASFLQGfDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT
|. ... |||| .. |. || |.|| .|| | .. ||..| .| |.| .| ||| | .|.. | || |.| .||..|..
keaqeagknrykdvgcldnnrvklegpwp.....heyihanyvst.ptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfask
NQPK----PYGQYTVSLCK---NEAFADY----TVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRfrkkIINESRHNTAPWIVHCSAGVGRT
.... || . .. . | . .| || | ...| . .||. |||.||| .|.| .....| | .||||||.|||
dkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlaile....llekarpskgpivvhcsagigrt
GAFIVIDAMLRQAKEKKVVD-IYNYVRATRGDRPNMVQTKDQYVFIHRAVLE
|. .... .| | . .... .. | .| | .|| .||.|.|. .|.
gsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
329-529 |
2.4e-41 |
136.7 |
In-house |
2-165 (174) |
alignment |
Range on Protein: 329-529
Range on HMM: 2-165/174.0
ADYINASFAHAYRERNAFILTQAPLEdtiasFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSqgaeeyggikvelqeeddksffisrrfdittKGKST
||||||. . .. . .|..|.||. ||.|. .... |.|||... | . . ...|||. . ..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lredl
PQRICHFQVTNWSDHSVPDKPLdLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKvEHVVDVFQAVKNLRISRPGAVETLEQYKFCY
. ..... ..| ||.||| . || ... ... ....... ..| || ||||.|||.|.. .. . . | .||... |. || |||.|.| .||.|.|
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
DV
..
yf
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
328-535 |
4.8e-41 |
136.5 |
In-house |
3-226 (272) |
alignment |
Range on Protein: 328-535
Range on HMM: 3-226/272.0
GADYINASFAHAYRE---RNAFILTQAPLEDTIASFWRMvVDYDLGTIVMLNSLDEEDEHF-PRYWP------------SQGAEEYGGIKVELQEEDDKS
.||||.. | .........||. |.|.|||. .... |||.| |..| . . .|||| | .|| . | |..| ..
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
FFISRRFDITTK-GKSTPQRICHFQVTNWSDHSVPDKPldLLPLLNDIQTsqqksgDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVD--------V
..| |.. .| . . ... .. |.. |.| ||.||... || ||. ... .....| || |..|.||..|. ....| | .|| .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQAVKNLRISRPGAVETLEQYKFCYDVTLAYLD
..||. || |||||.| |||.|.|.. |..|.
eeaveelraqrpgavqteeqylflyeallellr
|
subfamily_Sponge-PTP6_pd |
Subfamily Sponge-PTP6 |
283-531 |
4.6e-40 |
132.4 |
In-house |
29-276 (439) |
alignment |
Range on Protein: 283-531
Range on HMM: 29-276/439.0
IFWLSPDVRVES--ASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDE
| ||| .... |.. . .|||. |. ..| ||.|. . | . |||| . . | . . .| ||.| ..| .|||.|.. ||||| | |
instspdyaciaslaaqeydqtknrykdvgafdhtrvtlq.eipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlve
EDEhfprYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTP--QRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGV
||||.. || | | . . . .. | | . . .| . . .|. . | |. || . .| .| |.....| .||.|| ||
syk....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagv
GRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
||.||. |. .|..|.| ||. || || | |..| || | |. |
GrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavl
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
33-236 |
5.2e-40 |
132.3 |
In-house |
2-154 (172) |
alignment |
Range on Protein: 33-236
Range on HMM: 2-154/172.0
DGRSDYINASFLQGFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLiegskekchkywpdtnqpkpygqytvslckneafadytvrtflvTS
|..|||||||.| . |...|| ||| ..|||.|.... ...||.||.| .
degsdyinasyldlyy.ipdrfiatqgplrntladfwrmlkelgithivnltel............................................ly
APSNEQRFIYQYHFTVWPDKGVPqYATAVLRFRKKIIN-ESRHNTAPWIVHCSAGVGRTGAFIVIDAMLrqaKEKKVVDIYNYVRATRgdrPNMVQTKDQ
|....|...||... ||| ||| . .|.| . | . . . | .|||||||||||...... || . .. .....||. | |..||...|
dpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml...lglsleeavalvrekR...pgavqnpsq
YVFIH
| |..
yrfly
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
33-241 |
6.9e-40 |
132.0 |
In-house |
9-171 (176) |
alignment |
Range on Protein: 33-241
Range on HMM: 9-171/176.0
DGRSDYINASFLQGFdgtpkKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPKPygqytvslckneafadytvrtflvts
|. .|||||... | ..|| |||.. .. ||..|.........|.|| ..| .. ||. |||. ...
dldldyinanlilgs.....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..........................
apsneqrfiyQYHFTVWPDKGVPQYaTAVLRFRKKIINESRHNtAPWIVHCSAGVGRTGAFIVIDAMLRqakeKKVVDIYNYVRATRGDRP-NMVQTKDQ
||... ||| |||.. ...|.. . | . ... | .||||||.||||...... . . .| ..... .. | || ..||| .|
..........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQ
YVFIHRAVLE
| |.....|.
yrflyefell
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
286-535 |
8.7e-40 |
132.7 |
In-house |
32-281 (314) |
alignment |
Range on Protein: 286-535
Range on HMM: 32-281/314.0
LSPDVRVESASRACNASKNRFPDILPLDsHRVALhlSVDKDPGADYINASFAHAYrerNAFILTQAPLEDTIASF----------WRMVV--DYDLGTIV
. |. . |. .| .|||..|||| | .|| | . | ||||||. . . ..|| ||.||| |. .| ||||. |... .||
vlpeltilvadlflnrdknryldilpad.nrvil..pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdiv
M---------------------LNSLDEEDehfpRYWPSQGAEEYGgikvelqeeddksffisrrfDITTKGKSTPQRICHFQVTNWSDHSVPdKPLDLL
| |..||. ... . |.. .... .. .... .. ....|.|.| . |..
msrdevladelsrLdaAlgKtpllildgng....neptaadlellk....................eelydpelferlgikylripvpDgsap.lledfd
PLLNDIQTSqqkSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKvehvVDVFQAVKNLRISRP-----GAVETLEQYKFCYDVTLAYLD
.|. |.. . .....| |..|.||.||..... .. . . |.. .|.. .| || |..|.|||| |.... | ||.
eflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyefilealleylk
|
subfamily_PTPRN_pd |
Subfamily PTPRN |
292-528 |
1.9e-39 |
130.2 |
In-house |
48-286 (297) |
alignment |
Range on Protein: 292-528
Range on HMM: 48-286/297.0
VESASRACNASKNRFPDILPLDSHRVALHLSVDKDpGADYINASFAHAYRERN-AFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEH-FPRYW
| |.. |..||| ..|| | || |. . ... ||||||. |. |.| ||.|| .|.|.||.|| . ||.| .|.||. . |||
kevakaeknvkknrskavlpydhsrvklkeeasae.ksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckryw
PSQGAEEYGGIKVELQEEDDK-SFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKsGDKAIVVQCSDGVGRSGTLCAIM
| .|.| |. .|.| | .. | | . .| . . | | ...|| .. || . .. | . .||| ||||.||.|. ..|
pdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcsdGaGrtGvyilid
SVIERV-KVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYD
|..|. | . .|. ... || ||| |.| .|..|..
lvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalt
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
326-528 |
3.7e-38 |
126.3 |
In-house |
2-155 (172) |
alignment |
Range on Protein: 326-528
Range on HMM: 2-155/172.0
DPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLdeedehfprywpsqgaeeyggikvelqeeddksffisrrfdiTTKGK
|.| ||||||. . |. . || ||.|| |.|.||||. ... ..||.|..| .. ..
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpe
STPQRICHFQVTNWSDHSVPdKPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIervkveHVVDVFQAVKNLRISRPGAVETLEQYKF
. ..... ..| ||.|| . || .|. |.. ...| .....| || ||||.|||.|. .. . .....||. .| |||||.. .||.|
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
CYD
.|.
lyy
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
325-534 |
6.7e-38 |
125.5 |
In-house |
8-173 (176) |
alignment |
Range on Protein: 325-534
Range on HMM: 8-173/176.0
KDPGADYINASFAHAYRernaFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEH-FPRYWPSqgAEEYGGikvelqeeddksffisrrfdittk
|.. |||||... .| .| ||.||..|.|.|..|. ... ...|.|... | . . .|.||| |..|
ldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi........................
gkstpqricHFQVTNWSDHSVPDKpLDLLPLLNDIQTSQQKSgdKAIVVQCSDGVGRSGTLCAIMsvieRVKVEHVVDVFQAVKNLRISRP-GAVETLEQ
......| ||.||| .|| ||. |.. ... . ..| || |.||.|||.|. .. |. ..|..|.. .| || |||.| ||
.........qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQ
YKFCYDVTLAYL
|.|.|.. | .|
yrflyefellll
|
subfamily_Cele-PTP-15_pd |
Subfamily Cele-PTP-15 |
8-244 |
8.5e-38 |
124.9 |
In-house |
37-271 (285) |
alignment |
Range on Protein: 8-244
Range on HMM: 37-271/285.0
IKNRYGNIVTYDHTRVVLKgpggNRDgrSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN-QPKP
||| .. . |||||| |.| ||| ||... ||..|||. . |||.|..||. . ..|| |.|| ||| |.|. .
dlnryadvrcieetrvvlk....nhd..rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvk
YGQYTVSL--CKNEAFADYTVRTFLVTSAPSNEQRFIYQYHF--TVWPDKGVPQYATAVLRFRKKiINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQ
.|.| ..| ||.|| | . .. |. . .| | |||. |. | .. . | ... . | |||||||||| .|. || .
fgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykw.vkkvnpkekpicvhcsagvgrtatfvgidyatir
AKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALV
|. ... . || | | . ||.. |..|.. ..| ..
imenpniemldivremramrfqavqshmqflflyvvlmeyfi
|
subfamily_Choan-PTP-3_pd |
Subfamily Choan-PTP-3 |
276-533 |
1.5e-37 |
124.0 |
In-house |
14-276 (287) |
alignment |
Range on Protein: 276-533
Range on HMM: 14-276/287.0
SEFQRLSIFWLSPDVRVESASRACNASKNRFPDILPLDSHRVAlhLSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVML
|...| | . .| ...|||. |.||.| || || . . |.||||| . .|.. .||| .|.|. |. .|||.|.. .....
kevdalkedsesstatfkaaeelaavkknryadvlPiddtrvl..lsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitm
-NSLDEEDEHFPRYWPSQGA-EEYGGIKVELQEEDDKSF-FISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDI----QTSQQKSGDK
..| . .||| . || | | . | |. . | . . . . ... .| |.... . |. . |. . ... |.
treveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevG
AIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
.|| .. |.||||.| |.. ...| . ||| ..| || | . | . |... |. .|
PlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvty
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
50-236 |
1.9e-37 |
123.6 |
In-house |
7-143 (152) |
alignment |
Range on Protein: 50-236
Range on HMM: 7-143/152.0
TPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWpdtnqpkpygqytvslckneafadytvrtflvtsapsneqrfiyQYHFTVW
|...||.||| . ...|||.|... ...||||| | | |.||..|. ||... |
mpfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................qylhlpw
PDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLrqaKEKKVVDIYNYVRATRgdrPNMVQTKDQYVFIH
|| |||. . .| . . | ... | .|||||||||||...... || . .. .....||. | |..|....|. |..
pDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml...lgvsleeavalvrekR...pgavpnpgqlrfly
|
subfamily_ptpA1_pd |
Subfamily ptpA1 |
3-202 |
5.1e-37 |
122.6 |
In-house |
44-255 (418) |
alignment |
Range on Protein: 3-202
Range on HMM: 44-255/418.0
KPENKIKNRYGNIVTYDHTRVVLKGPGgNRDGrSDYINASFLQGfdGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN
| | |||| ||. .|||| || ...| |||||| ...| ||..|..|||. . |||.|||..|| .||||. | . || .|||.
kkhntsknrytnilpvnhtrvqlkkiq.dkeg.sdyinanyidg..aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqi
QPKpygQYTVSLCKNEAFADYTVRTFLVTSAP-------------SNEQRFIYQYHFTVWPDKGVPQYATAVLRF------RKKIINESRHNTAPWIVHC
. |... || | |.| | | | | | ||.. |||. .|... . .. |.. | | | ||||
gge...qfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhc
SAGVGRTGAFIVIDAMLRQ
||||||||.| |...
sagvgrtgtfctavimmkk
|
subfamily_Cele-PTP-10_pd |
Subfamily Cele-PTP-10 |
6-243 |
8.5e-37 |
121.4 |
In-house |
55-289 (305) |
alignment |
Range on Protein: 6-243
Range on HMM: 55-289/305.0
NKIKNRYGNIVTYDHTRVVLKGPGgnrdgRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPK
.. |||| .. |.. | |. | |||| | .. |..|.||||.. . |.|| || |.. |||| .| | || .||| .. |
aitknryqdvpcqdqsavkldkps.....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgek
PYGQY-----TVSLCKNEAfADYTVR-TFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFrkkiINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
. || .| | .. | | . ... . . ..| |||.||| . | . . | | .||||||.||||. . |. .
lelksgivvenvsgskpme.rdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslel....lsairgskvpivvhcsagigrtgtivaieyi
LRQ-AKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
| . |..|.. . . |.| | .| .|. ||.|||| .|. .
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
subfamily_Anemone-PTP-1_pd |
Subfamily Anemone-PTP-1 |
293-527 |
1.8e-36 |
120.5 |
In-house |
1-234 (239) |
alignment |
Range on Protein: 293-527
Range on HMM: 1-234/239.0
ESASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRE-RNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWP
|.| . | .|||. .|. | || | . .|| .||||||. . | .|.| || .| . ||||. . |||| | | .. .|||
eaakkrvnkaknryanivtydhsrvvle.klsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp
SQgAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIqTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSV
. .| ..| |.. . . .| | | .. |.. . . ....| | |. ||. .| | | | . | . |..|| ||||.|.. | ..
ds.tskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihcsagvgrtgaflvidam
IERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCY
. . | .. ||.|. || .| || |.| ||| | .
lrqakkqktvdifnyvkairedrphmvqtseqyvfih
|
subfamily_Cele-PTP-13_pd |
Subfamily Cele-PTP-13 |
3-242 |
1.9e-36 |
120.2 |
In-house |
34-268 (281) |
alignment |
Range on Protein: 3-242
Range on HMM: 34-268/281.0
KPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgRSDYINASFLQGfDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN
.| |. |||| || | .|| || |.. .||| | ... . || .||| . . |||.|.||| . |||| ..| .||| .|.|
qpvnnkknrylnipcldisrvqlkvkmpnkn.stdyihanyirs.pflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprna
QP-KPYGQYTVSlcKNEAFAD-YTVRTFLvTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIinesRHNTAPWIVHCSAGVGRTGAFIVIDAML
. . ...|| ... . | | | . | |.| .. . ||| ||. . .|. .|| | ..| ..||||||||.|... .. |
hcclqfdklsvs..yedstvnkslvttrl.nlsyegetrlithwlwkewpdwqvpessevmlkilrki....rarstppvihcsagvgrsgtlmaveial
RQAKEK-KVVDIYNYVRATR-GDRPNMVQTKDQYVFIHRAVLEA
. . . . || . | | | ||| .||..| . .|.
qsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
subfamily_Nvec-PTP-1_pd |
Subfamily Nvec-PTP-1 |
295-527 |
3.6e-36 |
119.5 |
In-house |
2-233 (239) |
alignment |
Range on Protein: 295-527
Range on HMM: 2-233/239.0
ASRACNASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRE-RNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQ
| . | .|||. .|. | || | . .|| .||||||. . | .|.| || .| . ||||. . |||| | | .. .|||
akkrvnkaknryanivtydhsrvvle.klsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds
gAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIqTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIE
. .| ..| |.. . . .| | | .. |.. . . ....| | |. ||. .| | | | . | . |..|| ||||.|.. | ...
.tskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihcsagvgrtgaflvidamlr
RVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCY
. | .. ||.|. || .| || |.| ||| | .
qakkqktvdifnyvkairedrphmvqtseqyvfih
|
subfamily_Cele-PTP-8_pd |
Subfamily Cele-PTP-8 |
6-245 |
1.7e-35 |
117.4 |
In-house |
43-273 (288) |
alignment |
Range on Protein: 6-245
Range on HMM: 43-273/288.0
NKIKNRYGNIVTYDHTRVVLKgpggnrDGRSDYINASFLQgFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN-QP
| ..|| |. | ||| |. | ||.| . ... | || |.. . .|.|. .. ||||. |.| ||| .|.| .
nptrdryenlprcditrvkls......ddpdfyiaanvvs.sakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGek
KPYGQYTVSLCKNEAFADYTVRTFLV-TSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIinesRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQA
.|.. |. | | .|. |. | . .|. .. . |. |.|.|||. . ||. . . . . | .||.||||||||..|.| .|...
arigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl....kslqkPivvhssaGvGrtgtlililialesl
KEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVC
. . . | . . | .| . .||. ||...|| ||| |.
rlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
137-280 |
1.8e-34 |
113.8 |
In-house |
87-231 (440) |
alignment |
Range on Protein: 137-280
Range on HMM: 87-231/440.0
EQRFIYQYHFTVWPDKGVPQYATAVLRFRKKiINESRH--NTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVF
| | . |||. |||||||..| ||.. . .|||.. .| .||||||.|||| |..|..||.|| .||.... . | .||.|||| .||.|
esrtlkqyhyqgwpdkgvpkfagpvlkmiqd.vnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
IHRAVLEALVCGSTDIQAPNLRNVMTKLEKIRPREQVSGYESEFQR
.| ||||.|.|| | | .. . . ... |. . | . ||.
vheavlegllcgdtliledditerveqiqwpnphtdksplqqefeg
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
36-240 |
4.9e-34 |
112.5 |
In-house |
3-150 (151) |
alignment |
Range on Protein: 36-240
Range on HMM: 3-150/151.0
SDYINASFLQGFdgtpkkYIAAQGPVEpscdDFWQMVWQERCSVIVMLTGLIEGSkeKCHKYWPDTNqpkpygqytvslckneafadytvrtflvtsaps
|||||.|.. |. ... .|| . ||....... ...||.|... | .|..|.|...
sdyinfsyvtgg......lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
neqRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINesrHNTAPWIVHCSAGVGRTGAFIVIDAMLRQakeKKVVDIYNYVRATRGdrpNMVQTKDQYVFI
. ....... ||| |.|.. |||.| ..... .. | .||||||.||||...... ||.. . ......|..|. ..||...|..|.
...ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg...vsleealeeyrlkrp...gvvqpnqqflfq
HRAVL
..|.|
lfall
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
339-528 |
8.6e-34 |
111.8 |
In-house |
4-144 (152) |
alignment |
Range on Protein: 339-528
Range on HMM: 4-144/152.0
AYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWpsqgaeeyggikvelqeeddksffisrrfdittkgkstpqricHFQVT
|. ..|| ||.|.. |.|.||||. ... .|||||..|.| .. ...|. ... .
gyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qylhl
NWSDHSVPDKPLDLLPLLNDIQTSqQKSGDKAIVVQCSDGVGRSGTLCAIMSVIervkveHVVDVFQAVKNLRISRPGAVETLEQYKFCYD
.| ||.||| . || || |. ... .. ..| || ||||.|||.|. .. . |....||. .| |||||.. .|..|.|.
pwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
PTPc_DSPc_SM00012 |
|
141-241 |
2.8e-33 |
109.6 |
In-house |
2-105 (105) |
alignment |
Range on Protein: 141-241
Range on HMM: 2-105/105.0
IYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNT--APWIVHCSAGVGRTGAFIVIDAMLRQAKEK-KVVDIYNYVRATRGDRPNMVQTKDQYVFIHR
...||.| |||.|||......|.. ... .. .... .| .||||||||||| |...| .|.| ... | |||...|.. | ||.||||..||.|..|
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVLE
|.||
alle
|
subfamily_Anemone-PTP-4_pd |
Subfamily Anemone-PTP-4 |
300-529 |
5.3e-33 |
109.2 |
In-house |
3-234 (237) |
alignment |
Range on Protein: 300-529
Range on HMM: 3-234/237.0
NASKNRFPDILPLDSHRVALHLSVDKdpgADYINASFAHAYRE-RNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWPSQG-AEE
| |||. .| | || |. . . .|||||.. . . . .| .| ||| . ||.|| . |||| | | .| . .|||| .
nkiknrygnivaydhsrvvlkgagsg...sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICH-FQVTNWSDHSVPDKPLDLLPLLNDI-QTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERV
|| . | |. ... | . | . ...... |. | .| | | |. ||.. || . .| . |. | .. || ||||.| . | ... .
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
| ..|||... |... || ..| .|| | ...
kekkvvdiynyvysieedrpyiiqtkdqyvfihqt
|
subfamily_Cele-PTP-19_pd |
Subfamily Cele-PTP-19 |
33-235 |
1.4e-32 |
107.7 |
In-house |
72-273 (301) |
alignment |
Range on Protein: 33-235
Range on HMM: 72-273/301.0
DGRSDYINASFLQGFdGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPD-TNQPKPYGQYTVSLCKNEAFADYT--VRTFL
||. | | ... | |...||.|||.. ...||| |. | ||||. .| .|||..| | ... |.... . ..| . ||.
dGkrvPihanwipts.GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtle
VTS-APSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRkKIINESrhnTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQT
|. . . | . | .. |.|.|||. . . . ... .| | .||||||.||. ||| . . |. . .. ... . .. | .| | |||
vedstgkfatrtvthyqysewtdrgvPkshaelfdlm.elvkks...ekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqt
KDQYVFI
. | ..
nsqlywm
|
subfamily_Cele-PTP-11_pd |
Subfamily Cele-PTP-11 |
9-245 |
1.7e-32 |
107.4 |
In-house |
46-278 (312) |
alignment |
Range on Protein: 9-245
Range on HMM: 46-278/312.0
KNRYGNIVTYDHTRVVLKGpggnrDgRSDYINASFLQgFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDT------N
||| || .| | | | | || | |.. |......|||.| .| |||.. .. |..|.|..| . ||| || | .
lnrypniqcwdrgrftlag.....d.enfyihanfvk.ictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdle
QPKPYGQYTVSLCKNEAF-ADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFrkkiINESRHNTAPWIVHCSAGVGRTGAFIVIDAM--
. . | .| . | | . | . .. . .| .. |||.|.|. . ||. . ... | | ||||||||||....|..|
dhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrl....lsavkkdkkpviahcsagvgrtgtlaliesmia
-LRQAKEKKVVDIYNYVratRGDRPNMVQTKDQYVFIHRAVLEALVC
||. . ..| |.. . | || |.. |||. |.||| | .
alrhprkqnvkdsfvll...rkdrarsvrvfpqyvyalrcvleflys
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
18-239 |
2.8e-32 |
107.2 |
In-house |
2-167 (178) |
alignment |
Range on Protein: 18-239
Range on HMM: 2-167/178.0
YDHTRVVLKGPggNRDGRSDYINASFLQGFdgtpkKYIAAQGPvepscDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQpkpygqytvslckn
.|.|||.| . . ||||||||. .. |.....| |........ ...||.||. .|. ..||..|||. .
ldrtrvllsnl..eglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag..............
eafadytvrtflvtsapsneqrfiYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQakEKKVVDIYNYVRA
.||... .|| |||. .|.| . | . . | .|||||||||.|...... |... . .....||.
........................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl..glsleeaielvre
TRgdrPnMVQTKDQYVFIHRAV
| | .|.. .|. ....
rR...p.ivpnpgqlrqLyefe
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
1-168 |
4.3e-32 |
106.2 |
In-house |
28-193 (297) |
alignment |
Range on Protein: 1-168
Range on HMM: 28-193/297.0
AKKPENKIKNRYGNIVTYDHTRVVLKGPGGNrdgrSDYINASFLQGFD-GTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWP
||.. |||| .|...| ||| |.. . .||||| .. | .. ||| ||||.. . ||||..|... ||||.. | |. ..|| |||
akrnsslrknryrdilatddtrvkllrvite....rdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywp
DTNQPKPY-GQYTVSLCKNEAfADY-TVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKI
...| . |.. | . . .. .| .. .|.| . | |||.||| . ||. ..
svvqerlkagdvvveflssts.defdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqv
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
292-531 |
5.8e-31 |
102.2 |
In-house |
46-280 (290) |
alignment |
Range on Protein: 292-531
Range on HMM: 46-280/290.0
VESASRACNA--SKNRFPDILPLDSHRVALHlsvDKDPGaDYINASFAHAYreRNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRY
.| |. |||. |. | || |. | .| ||. | . . . ||||| .|.||. .||||.. . .|||| | |. . .|
lerkifdkntefkknrykdvvcndktrvilk...dGydG.dyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqy
WPSQGAE--EYGGIKVELQEEDDKSFFISR-RFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSqqkSGdkAIVVQCSDGVGRSGTLC
.| . | .| | | ||||| | . . . | . .. |... | |.||. | || .| ... || .|| || |.||.||.
ypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka...sG..pvvvhcsaGiGrtGtfv
AIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
|| .. . . .|. . |. || || ..|. || .. |
aievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveill
|
subfamily_Cele-PTP-8_pd |
Subfamily Cele-PTP-8 |
299-534 |
1.6e-30 |
101.1 |
In-house |
42-271 (288) |
alignment |
Range on Protein: 299-534
Range on HMM: 42-271/288.0
CNASKNRFPDILPLDSHRVALHlsvdkDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQGAEEY
|....|. .. | || |. | ||.| . . .. .| .||||. || .|.|... |. ||||. | | |. |.||. |.
anptrdryenlprcditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGeka
GgIKVELQEEDDKSFFISRRFDIT----TKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIqtsqqKSGDKAIVVQCSDGVGRSGTLCAIMSVIER
|. . .| | . .. .| ... . . . .| |..||.. | | ||. . || .| |||..| ||||.||| |. ..|
r.igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililiales
VKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.... . . . ...|| .| |..| || . . . | .|
lrlddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
PTPc_DSPc_SM00012 |
|
433-531 |
3.7e-30 |
99.6 |
In-house |
4-104 (105) |
alignment |
Range on Protein: 433-531
Range on HMM: 4-104/105.0
HFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSG-DKAIVVQCSDGVGRSGTLCAIMSVIERVKVE-HVVDVFQAVKNLRISRPGAVETLEQYKFCYDVT
|...|.|.||.||... ..| ||........||. | .||.||.||||.||..|. ...... | . ||.|| || || .|||.|.|.||| |.|..
hyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyral
L
|
l
|
subfamily_ptpA1_pd |
Subfamily ptpA1 |
296-498 |
3.8e-30 |
99.9 |
In-house |
43-258 (418) |
alignment |
Range on Protein: 296-498
Range on HMM: 43-258/418.0
SRACNASKNRFPDILPLDSHRVALHLSVDKDpGADYINASFAHAYRErNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQ--
. |.||||. .|||.. || |. ||. |.||||| . . || || || .||| ||||| . ||||. |. . |||| |
dkkhntsknrytnilpvnhtrvqlkkiqdke.gsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqig
---------GAEEYGGIKVELQE--EDDKSFFISRRFDITTKGKStpQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQK---SGDK--AIVVQCSD
| | .| ||| | .| . |.| .| .|.. . | ..| | || .||. . || | |.. | |. |.|.||
geqfsiygngnevfgtysvelveviqdpereiitrnirltfeget..rditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsa
GVGRSGTLCAImsVIERVKVEH
||||.||.|. || |..|
gvgrtgtfcta..vimmkkldh
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
329-529 |
3.8e-30 |
99.9 |
In-house |
3-148 (151) |
alignment |
Range on Protein: 329-529
Range on HMM: 3-148/151.0
ADYINASFAHAYrernaFILTQAPLEdtiaSFWRMVVDYDLGTIVMLNSLDEEDeHFPRYWPSQGaeeyggikvelqeeddksffisrrfdittkgkstp
||||.|. . ......||. |.... .... |||.|.|..| . ..|.|.|..|
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg.ycpeylpelg...................................
QRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTsqqkSGDKAIVVQCSDGVGRSGTLCAIMSVIERvkvehvVDVFQAVKNLRISRPGAVETLEQYKFCYD
...|.....|.|...|. . .| .|. .. ... ..| || |.||.|||.|.. .... |....|.. .|..|||.| . .|. |..
ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
V
.
a
|
subfamily_CG42327_pd |
Subfamily CG42327 |
6-162 |
1.2e-29 |
98.0 |
In-house |
28-184 (319) |
alignment |
Range on Protein: 6-162
Range on HMM: 28-184/319.0
NKIKNRYGNIVTYDHTRVVLKGPGgnRDGRSDYINASFLQGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN---
| |.|. |.| .|||||. | | .. |..||...|.| .| ||||| . | | |||..||. . ||| || | | ..| .|.| .
skdksrvinvvPlPetrvvlqrig..dddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
QPKPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFtVWPDKGVPQYATAVL
. . ||.. |.| ..|. | . |.|. .| | . | . |.. .|| .|..
ntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaali
|
subfamily_Cele-PTP-14_pd |
Subfamily Cele-PTP-14 |
6-249 |
2.3e-29 |
97.0 |
In-house |
52-295 (310) |
alignment |
Range on Protein: 6-249
Range on HMM: 52-295/310.0
NKIKNRYGNIVTYDHTRVVLKGpggNRDGRSDYINASFLQGfDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPK
. |||| ..| | .|| || .. ||| | ... . . .| .|||.. . |||.|..|||. |..| | . || ||| .
ymhknrysdvvcldtsrvklki...dksryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvte
PYGQYTVSLCkNEAFADYTVR----TFLVTSAPSNEQRF------IYQYHFTVWPDKGVPQYATAVLrfRKKIINESRHntAPWIVHCSAGVGRTGAFIV
|| |. .|. .. . ||. | .|| . .. |||.|||. . .... . || | .||||||..|... .
tygcirvtnl.sesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtv..pqrllaqvrh..gpcvvhcsagkdrlyvvva
IDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLeALVCGSTD
.. . .... . ||. . . . .| .||. ||..|.| . ... | |.
lklkidkldrglkvdaeevktellksraiciqtelqyliidrvri.ifargete
|
subfamily_Cele-PTP-6_pd |
Subfamily Cele-PTP-6 |
276-534 |
2.9e-29 |
97.0 |
In-house |
20-277 (307) |
alignment |
Range on Protein: 276-534
Range on HMM: 20-277/307.0
SEFQRLSIfWlSPD-VRVESASraCNASKNRFPDILPLDSHRVALHLSvdkDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVM
||. |. . .|. | ||. | .|. |||. |. | |. .... .||| | . . . || .| |||.|. ||| |... .. ...|
defrvlak.k.tpegvtveafs..antdknryqdvkcqdkgrivvkfd...glasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvim
LNSL-DEEDEHFPRYWPSQ-GAE-EYG----GIKVEL----QEEDDKSFFISRRFDITTKGKStpQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQq
| . . . .||| . | . .| | |. . |. . ... .|| . | |.| .|| |. ||. | . ||. .. .
lckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqks..rtiqhlqwenwpdrgvpqinltainlleavrydt.
ksgdKAIVVQCSDGVGRSGTLCAIMSVIER-VKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.|| || |||||||. || | .. .. . |. . |..|| |. |..| || . . | | |.
....npvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
subfamily_Cele-PTP-13_pd |
Subfamily Cele-PTP-13 |
296-532 |
5e-29 |
95.8 |
In-house |
33-267 (281) |
alignment |
Range on Protein: 296-532
Range on HMM: 33-267/281.0
SRACNASKNRFPDILPLDSHRVALHLSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDE-EDEHFPRYWPSQGA
. | |||. .| || || |.. . . .||| | . .. . .|||| | ..| | ||||. . . .|||| . | . |. |.| .
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
--EEYGGIKVELQEEDDKSFFISRRFDITTKGKStpQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSqqkSgdKAIVVQCSDGVGRSGTLCAIMSVIE
.. . |. .. . ... |.... .|.. . | |. .| | ||. .| .| |.. | |..|| |||||||| |. ..
cclqfdklsvsyedstvnkslvttrlnlsyeget..rlithwlwkewpdwqvpessevmlkilrkirar...s..tppvihcsagvgrsgtlmaveialq
RVKVEH-VVDVFQAVKNLRIS-RPGAVETLEQYKFCYDVTLA
.. . |. | | ||.. | .|.||.|| . . | |
sihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
339-529 |
4.4e-28 |
92.8 |
In-house |
231-433 (440) |
alignment |
Range on Protein: 339-529
Range on HMM: 231-433/440.0
AYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDeeDEHFPRYWPSQG-AEEYGGIKVELQEEDDKSFFISRRFDIttKGKSTPQRICHFQVT
| .|||| || ||. |. |||.| || . ||.||| |. | ||| . . .| . | . .. | ... | | . | |.|
gyskknafiatqmpldstvldfwrlvhdyristiimlnqln..dktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlel..kykeevheirqfevq
NWS----------DHSVPDKPLDLLPLLN--DIQTS--QQKSGDK-AIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQ
| . . | |.|. |. .|| | | . || |.|.| |. || .|..| ..|... . .|||| .. ||.||| | || .
twptwiqsdgvqsqeqcmdavlqlmdylrkceiqrsteqsrpgdgppilvhclsgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvptltd
YKFCYDV
| .|| .
yllcykl
|
subfamily_egg_pd |
Subfamily egg |
5-240 |
3.1e-27 |
90.1 |
In-house |
39-267 (307) |
alignment |
Range on Protein: 5-240
Range on HMM: 39-267/307.0
ENKIKNRYGNIVTYDHTRVVLKGPGGNRDGrsDYINASFLQGfDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGskEKCHKYWPDT-NQ
.|. | | . | .|| |. . | . |.| | ..| . ..| || |. . ||||.||.||.. ||||| | |.|. ||| . ..
nnlekarskrvhckdssrvklelrrGqyld..dfihanrvkG.kpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesd
PKPY--GQYTVSLCKNEAFADYTVR-TFLVTSAPSNEQRFIYQYHFTVwpdkgvpQYATAVlRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDA--
. . | . . | . || | | | . .|.||. . | .... | . ... |. . | .|.. || ...... |.
slvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqgdv.......nnssdv.ysplrvlrklrnlskpvvvqdilGvskaatlvaieial
--MLRQAKEKKVvdIYNYVRATRGDRPNMVQTKDQYVFIHRAVL
.|| | . . . | | |. |.. .|.|..| ||
lsllrGpitksl..vlravvflrlrrrlsvesvllylfvyrlvl
|
subfamily_Cele-PTP-19_pd |
Subfamily Cele-PTP-19 |
302-523 |
1.5e-26 |
87.8 |
In-house |
52-270 (301) |
alignment |
Range on Protein: 302-523
Range on HMM: 52-270/301.0
SKNRFPDIlPLDSHrVALHLSVDkdPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLD-EEDEHFPRYWPSQGAEEYGG-
|.|.| . | . . |... || | | . . . . || ||.||..| || |.| ||. .|||| .. |. | |.. .|.
dkhryptv.PckPs.tavevivd..GkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldig
---IKVELQEEDDKSFFISRRFDIT-TKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSqqksgDKAIVVQCSDGVGRSGTLCAIMSVIERVK
||.. .| . . |..... . || ... . |.| ..|.|. || .| |.. .. | .| |||.||.|.||| .. . . .|.
rfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkks.....ekPivvhcsaGiGrsvafigteylareve
VEHVVDVFQAVKNLRISRPGAVETLEQY
. ... .|.|.|| | .| | .|
adptieltealkhlrehrwngvqtnsql
|
subfamily_Cele-PTP-10_pd |
Subfamily Cele-PTP-10 |
296-534 |
2e-26 |
87.3 |
In-house |
51-289 (305) |
alignment |
Range on Protein: 296-534
Range on HMM: 51-289/305.0
SRACNASKNRFPDILPLDSHRValhlSVDKDPGADYINASFAHAY-RERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNS-LDEEDEHFPRYWPSQG
| . .|||. |. | | .|| . .||| | . . . || .| ||..|| || ||.. . |||| .. . .|||
sadiaitknryqdvpcqdqsav....kldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaq
AEE---YGGIKVELQEeDDKSFFISRR-----FDITTKGKSTpQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQksgdkAIVVQCSDGVGRSGTLC
| .|| || | . ...| |. . . |.| |.| | || | | || |. |. |||.|| |.||.||.
geklelksgivvenvs.gskpmerdaeiqitllnltysgdqk.msvrhlqwtewpdrgvppckltslellsairgskv.....pivvhcsagigrtgtiv
AIMSVIERVKVEH-VVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
|| ..|.. .. . . . || || | .... || | . | | |.
aieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
subfamily_Cele-PTP-14_pd |
Subfamily Cele-PTP-14 |
300-533 |
2.4e-26 |
87.0 |
In-house |
52-289 (310) |
alignment |
Range on Protein: 300-533
Range on HMM: 52-289/310.0
NASKNRFPDILPLDSHRVALhlSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEhfPR---YWPSQGA-E
. |||. |.. ||. || | .|| ||| | . .. |..|| .| ||. || ||||. . .|..| || |. |||| | |
ymhknrysdvvcldtsrvkl..kidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegr..pkcvgywpslgvte
EYGGIKVELQEEDDKSFFISRrFDITTKGKS----------TPQRICHFQVTNWSDHSVPDKPLDLLPllnDIQTSQQKSGdkAIVVQCSDGVGRSGTLC
|| |.| | . | | . .| |. . || | |||. .| . .| . | ||.|| |..| ....
tygcirvtnlsesseefeicn.lavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp...qrllaqvrhg..pcvvhcsagkdrlyvvv
AIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
|. |.... . ||. . . .|. || ..| || . | ...
alklkidkldrglkvdaeevktellksraiciqtelqyliidrvriif
|
subfamily_egg_pd |
Subfamily egg |
289-533 |
9e-26 |
85.2 |
In-house |
29-269 (307) |
alignment |
Range on Protein: 289-533
Range on HMM: 29-269/307.0
DVRVESASRACNASKNRFPDILPLDSHRVALHLSVDKDPGaDYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEdEHFPRY
.. .. | . | | | . . || ||.|.| . . |.| | . | |||.|||| .| ||||| . ||||.| | |. . |
eislttaasdnnlekarskrvhckdssrvklelrrGqyld.dfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes.erceyy
WPSQGAEE----YGGIKVELQEEDDKSFFISR--RFDItTKGKSTPQRICHFQvTNWSDHSVPDKPLDLLPLLNDIQtsqqksgdKAIVVQCSDGVGRSG
|| .. |....| . |.|. . | .. . |. . . |.| .. | || .| .| .. | .|||. .|| ...
wpkaesdslvtvpGslrienlkvdskadplfrvtklkl.vGgddeerflehwq.gdvnnssdvysplrvlrklrnls........kpvvvqdilGvskaa
TLCAI----MSVIERvKVeHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
|| || .|.. . | .||. || |. .||. .| | | . | .
tlvaieiallsllrG.pi.tkslvlravvflrlrrrlsvesvllylfvyrlvlff
|
subfamily_Anemone-PTP-3_pd |
Subfamily Anemone-PTP-3 |
52-236 |
1.5e-25 |
84.6 |
In-house |
5-197 (199) |
alignment |
Range on Protein: 52-236
Range on HMM: 5-197/199.0
KKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQP-KPYGQYTVSLCKNEAFADYTVRTFLVTS---APSnEQRFIYQYHFT
..|||.| |. . |||||||. |||. . ||| |. || .|. . .|||. ....|. || | | .| ||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttapp.streishyqft
VWPDKGVPQYATA---VLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKK--VVDIYNYVRATRGDRPNMVQTKDQYVFIH
| .| |. | |. |. . . . || ||||| | | || |. .| .| .| | |||... . | | .. . ..| ||.
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
subfamily_Nvec-PTP-3_pd |
Subfamily Nvec-PTP-3 |
52-236 |
1.5e-25 |
84.5 |
In-house |
4-196 (198) |
alignment |
Range on Protein: 52-236
Range on HMM: 4-196/198.0
KKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQP-KPYGQYTVSLCKNEAFADYTVRTFLVTS---APSnEQRFIYQYHFT
..|||.| |. . |||||||. |||. . ||| |. || .|. . .|||. ....|. || | | .| ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttapp.streishyqft
VWPDKGVPQYATA---VLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKK--VVDIYNYVRATRGDRPNMVQTKDQYVFIH
| .| |. | |. |. . . . || ||||| | | || |. .| .| .| | |||... . | | .. . ..| ||.
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
324-529 |
1.8e-25 |
85.0 |
In-house |
13-166 (178) |
alignment |
Range on Protein: 324-529
Range on HMM: 13-166/178.0
DKDPGADYINASFAHAYrernaFILTQAPLedtiASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQGAeeyggikvelqeeddksffisrrfditt
...||||||. . ..|...| |...... ......||.|.. .| .. ..|||..
eglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag............................
kgkstpqriCHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGdKAIVVQCSDGVGRSGTLCAIMSVIERvkveHVvDVFQAVKNLRISRPgAVETLEQ
.... ....||.||| . .| ... |.. ....| ....| || ||||||||.|. .... .. ....|.. .| || .|.. .|
.........iqylhipipDhgvpdllehflefvefieealdekg.gpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgq
YKFCYDV
....|..
lrqLyef
|
subfamily_Cele-PTP-18_pd |
Subfamily Cele-PTP-18 |
273-534 |
5.2e-25 |
82.8 |
In-house |
23-287 (305) |
alignment |
Range on Protein: 273-534
Range on HMM: 23-287/305.0
GYESEFQRLSIFWlsPDVRVESASRACNASKNRFPDILPLDSHRVALHLSVDkdpgADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTI
| .||. . | .... | .| |||. |. || || |. . .|| | . . . . || ||||||.| | || | .. . .|
glraefvamkrfn..dfekmkafkeaqeagknrykdvgcldnnrvklegpwp....heyihanyvstptnpkrfictqaplektcadfwymclqdkveai
VMLNSLDEE-DEHFPRYWPSQGAEE----YGGIKVELQEEDDKS--FFISRR-----FDITTKGKS-TPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQ
|| | | .. |..|. .. .| |. .. | .. | . . .. .| . ... |. .| | || | .| ||.. .
fmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekar
TSQqksGdkAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVD-VFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.|. | ||| || |.||.|.. . ..... .... . .. .| | ...| .|| | ..| | |.
psk...g..pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
subfamily_Cele-PTP-4_pd |
Subfamily Cele-PTP-4 |
6-240 |
7.1e-25 |
82.0 |
In-house |
51-282 (302) |
alignment |
Range on Protein: 6-240
Range on HMM: 51-282/302.0
NKIKNRYGNIVTYDHTRVVLKGpggnrdGRSDYINASFLQGFDGTpKKYIAAQGPVEPSC---DDFWQMVWQERCSVIVMLTGLIEGSKeKCHKYWP-DT
| ||. .. .|...| |.. .|.||| .. . | .. | || |. | ..||.||.||.. .|.| | | .| ....| .
nlkknqsedvpildsnlvklea......epdsyvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks
NQPKPYGQYTVSLCKNEAFADYTvRTFLVTSAPSN--EQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAM
.. | ||. | | | . . . . | . . .. |..| |..| ||. ... . .|. ... . ... .. |.|| |||.. .
gdykeygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlava
LRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVL
. . ...| . | . |.. | .||..|.. .|||....|.|
veklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
97-240 |
1.5e-24 |
81.8 |
In-house |
2-140 (145) |
alignment |
Range on Protein: 97-240
Range on HMM: 2-140/145.0
YWPDTNQPKPYGQYTVSLCKNEAFADYTVRT-FLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRHNtAPWIVHCSAGVGRTGAFIV
|||. |. | . .. | ..|. ..| . .|| .... |...||... ||| |||. . .|.| . | . ... | .|||||||||||....
ywpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlva
IDAMLRqaKEKKVVDIYNYVRATRgdrPNMVQTKDQYVFIHRAVL
.. ||. . . .....||. | |..|.. .|. |.....|
aylmll..lgvsleealelvrsqr...pgavpnpgqlrflyefel
|
subfamily_Anemone-PTP-3_pd |
Subfamily Anemone-PTP-3 |
343-529 |
1.9e-24 |
81.0 |
In-house |
4-199 (199) |
alignment |
Range on Protein: 343-529
Range on HMM: 4-199/199.0
RNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWPS--QGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTP--QRICHFQVT
. .| || || .|.| ||.|| . | |||.| . . | .| |||. |. .|| . | . |. . . .| . . | . | |.| |
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
NWSDHSVPDKPLDLLPLLNDIQTSQ--QKSGDKAIVVQCSDGVGRSGTLCAIMSVI---ERVKvEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
| ... |. | . .. . |. .. | ..|.|||| | .| . |. . | | |||.|. | || .| | . .|..|.| |.|
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyqv
|
subfamily_Nvec-PTP-3_pd |
Subfamily Nvec-PTP-3 |
344-529 |
2.2e-24 |
80.7 |
In-house |
4-198 (198) |
alignment |
Range on Protein: 344-529
Range on HMM: 4-198/198.0
NAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWPS--QGAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTP--QRICHFQVTN
.| || || .|.| ||.|| . | |||.| . . | .| |||. |. .|| . | . |. . . .| . . | . | |.| |
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WSDHSVPDKPLDLLPLLNDIQTSQ--QKSGDKAIVVQCSDGVGRSGTLCAIMSVI---ERVKvEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
| ... |. | . .. . |. .. | ..|.|||| | .| . |. . | | |||.|. | || .| | . .|..|.| |.|
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyqv
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
117-237 |
2.9e-23 |
77.6 |
In-house |
22-139 (144) |
alignment |
Range on Protein: 117-237
Range on HMM: 22-139/144.0
NEAFAD---YTVRTFLVTSAPSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKKIINESRhNTAPWIVHCSAGVGRTGAFIVIDAMLrqakEKKvVDIYN
| ... .|| .. . | . |...||... ||| |||.... .|.| . | . . . | .|||||||||||...... |. ... .....
lellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaaylmk....klg.lslee
YVRATRGDRPNMVQTKDQYVFIHR
.. | ||..|.. .|. |...
alalvrsrrpgavpnpgqlrfLle
|
subfamily_Cele-PTP-4_pd |
Subfamily Cele-PTP-4 |
300-534 |
4.4e-23 |
76.2 |
In-house |
51-285 (302) |
alignment |
Range on Protein: 300-534
Range on HMM: 51-285/302.0
NASKNRFPDILPLDSHRVALHLSVDkdpgaDYINASFAHAYRERNAFILTQAPLEDTI---ASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWP--SQGA
| .||. .|. |||..| |. . | .|.||| . .. ||.| | |. ..||||| . ..|.| .| .. . ..| |.
nlkknqsedvpildsnlvkleaepd.....syvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlselfpkksgdy
EEYGGIKV-----ELQEEDDKSFFIsrrfDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIqTSQQKSGDKAIVVQCSDGVGRSGTLCAIMS
.||| . | | .||. . . | .. .| | . .||| ...||.| .| .. .. ..|. .|. |.|| |.. . .
keygkmfvNnrkVekaeeektryvi....EvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagafltlav
VIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
..|... .. . . . ||..| || ||..|.|| . | ..| |.
aveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
7-102 |
6.3e-23 |
76.0 |
In-house |
48-154 (350) |
alignment |
Range on Protein: 7-102
Range on HMM: 48-154/350.0
KIKNRYGNIVTYDHTRVVLK----GPGGNRD--GRSDYINASFLQGF----DGTPK-KYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCH
|||| ||. |.|.|| || . . . .|||||..|. . |. ||||.|.|. |||.... . ||..|| ..| |||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
KYWPDTN
.||.. .
rYWqegs
|
subfamily_Cele-PTP-9_pd |
Subfamily Cele-PTP-9 |
64-242 |
1.8e-22 |
74.7 |
In-house |
40-220 (255) |
alignment |
Range on Protein: 64-242
Range on HMM: 40-220/255.0
SCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPKPYgQYTVSLCKNEAFADYTVRTFLVTSAPS--NEQRFIYQYHFTVWPDKGVPQYATAV
. | |.|.. | . .|.|||. . | ..|||..|.| . | |... .. || .|| .|| . . . . |... |..| |. | .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklk.ladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelarei
LRFRkKIINESRhntaPWIVHCSAGVGRTGAFIVIDA----MLRQAKEKKVVD--IYNYVRATRGDRPNMVQTKDQYVFIHRAVLEA
| |.. .|. . .||||.|.||. ||.... |.|. .. . |. . .. .| |. ..| | | ||.
lnil.kvvrdsk....svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldl
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
388-531 |
2.1e-22 |
74.8 |
In-house |
2-140 (145) |
alignment |
Range on Protein: 388-531
Range on HMM: 2-140/145.0
YWPSQGAEE--YGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSgdKAIVVQCSDGVGRSGTLC
||||. . .|.. . |. | |.. | . ...|. . . ..... ..| ||.||| . .|| .|. |.. ... . ..| || ||||.|||.
ywpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlv
AIMSVIErvkvEHvVDVFQAVKNLRISRPGAVETLEQYKFCYDVTL
|.. ... .. |....|.. .| |||||.. .|..|.|.. |
aaylmll....lg.vsleealelvrsqrpgavpnpgqlrflyefel
|
subfamily_Cele-PTP-15_pd |
Subfamily Cele-PTP-15 |
298-533 |
4.8e-22 |
73.2 |
In-house |
33-269 (285) |
alignment |
Range on Protein: 298-533
Range on HMM: 33-269/285.0
ACNASKNRFPDILPLDSHRVALhlsvdKDPGADYINASFAHA-YRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQGAE
.| ||. |. .. || | |. ||| ||. . ......| || || .|.. ||.|. . . ..|| .| | |. |.| . |
eanpdlnryadvrcieetrvvl.....knhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
--EYGGIKVELQEEDDKSF----FISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQKsgDKAIVVQCSDGVGRSGTLCAIMS
..| .. | | ... . . | | | . | || | |. |. .. | . .. . | .| |.|.|| ||||. |. |
vvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhcsagvgrtatfvgidy
VIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
|. . ..... |...| | ||.. |. | | | . |
atirimenpniemldivremramrfqavqshmqflflyvvlmey
|
subfamily_Cele-PTP-7_pd |
Subfamily Cele-PTP-7 |
47-243 |
1.2e-21 |
71.5 |
In-house |
83-288 (302) |
alignment |
Range on Protein: 47-243
Range on HMM: 83-288/302.0
FDGTPKKYIAAQGPVEP---SCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQP-KPYGQYTVSLCK-NEAFADYTV------RTFLVTSA--
||| || .. |. | ... .| .. | . ...| |....|. ..|| .|. | . .|.||| . .. ....| | ..
mdGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekk
PSNEQRFIYQYHFTVWPDKGVPQYATAVLRFRKkIInESrhNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYV
.. .. . .|. |||.| |. | . | | || .|||||||||||... | . ..||| |. . | | | ||...| .
kkkvkktvdilafsawpdhGapkeaytaldilk.fc.es..ykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqli
FIHRAVLEAL
.. | .|
ylllcvtkgl
|
subfamily_CG42327_pd |
Subfamily CG42327 |
300-461 |
3.3e-21 |
70.3 |
In-house |
28-193 (319) |
alignment |
Range on Protein: 300-461
Range on HMM: 28-193/319.0
NASKNRFPDILPLDSHRVALHlSVDKDPGADYINASFAHAYRE-RNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYWPSQ----G
|.|. ...|| || |. .. .|. |..||. |.. .| .| .|..|||. ..|||.| . .|| | .| | . ..|.|.. .
skdksrvinvvPlPetrvvlq.rigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldn
AEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVtNWSDHSVPDKPLDLLPLLNDIQTS
. || |.| |.. . | .. . . |. . . |. .| . || .. |. .| ....|
tslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
293-450 |
4.1e-21 |
70.1 |
In-house |
26-185 (297) |
alignment |
Range on Protein: 293-450
Range on HMM: 26-185/297.0
ESASRACNASKNRFPDILPLDSHRVALHLSVdkdPGADYINASFAHAYRERN--AFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-EHFPRYW
|| | |||. ||| |. || | .. .. ||||| . | . .||.| ||..|. ||..|.. |...|||. | |. . ||
ssakrnsslrknryrdilatddtrvkllrvi...terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapyw
PSQ--GAEEYGGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLD
|| . . | . || . | ... .| . . | | .| || || |
psvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdled
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
416-528 |
7.4e-21 |
69.8 |
In-house |
48-139 (144) |
alignment |
Range on Protein: 416-528
Range on HMM: 48-139/144.0
RrfdittkgkstpqrICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQQksGDKAIVVQCSDGVGRSGTLCAIMSVIervkVEHvVDVFQAVKNLRISRPG
..... ..| ||.||| . .|| .|. |.. .. .. ..| || ||||.|||.|. .. ... .....|.. .| |||
e..............giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpg
AVETLEQYKFCYD
||.. .|..|...
avpnpgqlrfLle
|
subfamily_Sponge-PTP4_pd |
Subfamily Sponge-PTP4 |
287-445 |
7.9e-21 |
68.8 |
In-house |
82-237 (244) |
alignment |
Range on Protein: 287-445
Range on HMM: 82-237/244.0
SPDVRV-ESASRACNASKNRFPDILPLDSHRVALHlsvDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHF
|| | . | |. ||| ||.| || | | |||||| .|||| || || ||.|... . .|.| |..||||..
rpdpsvmkdafnpnnswknregaglpfdfnrvpls...kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeedeyw
PRYWPSQGAEEygGIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNW-SDHSVP
| | . || | | | . |. . ..| . . . | . ||..|| || . |
pdseplewyee..ditvtltdrdefknikasnleiesdmneshqaltmfqisnwpsdgttp
|
subfamily_Cele-PTP-11_pd |
Subfamily Cele-PTP-11 |
303-534 |
1.2e-19 |
65.1 |
In-house |
46-276 (312) |
alignment |
Range on Protein: 303-534
Range on HMM: 46-276/312.0
KNRFPDILPLDSHRVALhlSVDKDpgaDYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQ-G------A
||.|.| | | .| . |.. || | | . . |. ||.|||.|.. ||.... .|..| .. |. |. .| |
lnrypniqcwdrgrftl..agden...fyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledh
EEYGGIKVELQE-EDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIqtsqqKSGDKAIVVQCSDGVGRSGTLCAIMSVIER
| |.. | | . . | .. |.| . | || .|| | || . | | .. .|| ||||.|||. | |.|
rvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsav.....kkdkkpviahcsagvgrtgtlaliesmiaa
VKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.. .| .. || | .|... || .. . | .|
lrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefl
|
subfamily_Sponge-PTP-7_pd |
Subfamily Sponge-PTP-7 |
180-246 |
3.4e-19 |
63.0 |
In-house |
2-68 (69) |
alignment |
Range on Protein: 180-246
Range on HMM: 2-68/69.0
IVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCG
.||||.| ||||.|| | . . | .|.|||.| |. | || || . .|.||| |. ||| |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
subfamily_Sponge-PTP7_pd |
Subfamily Sponge-PTP7 |
180-246 |
8.3e-19 |
61.7 |
In-house |
1-67 (69) |
alignment |
Range on Protein: 180-246
Range on HMM: 1-67/69.0
IVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVCG
.||||.| ||||.|| | . . | .|.|||.| |. | || || ...|.||| |. ||| |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
subfamily_hpo-7_pd |
Subfamily hpo-7 |
65-241 |
5.5e-18 |
59.8 |
In-house |
47-225 (263) |
alignment |
Range on Protein: 65-241
Range on HMM: 47-225/263.0
CDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPKPyGQYTVSLCKNEAFADYTVRTFLVTSAPS--NEQRFIYQYHFTVWPDKGVPQYATAVL
| |.|.. | . .|.|||. | ..||| .|.| | |..| .. | ..| ..| . . . . .| .. |..| |. | .|
idkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekq.klanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelareil
RfrkkIINESRHNtAPWIVHCSAGVGRTGAFIVIDA----MLRQAKEKKVVDI--YNYVRATRGDRPNMVQTKDQYVFIHRAVLE
. |.. |. . .||||.|.||. || |.. |.|. .. . |.. . .. .| |. ..| | | ||.
n....ilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLd
|
subfamily_Cele-PTP-1_pd |
Subfamily Cele-PTP-1 |
17-250 |
1.1e-17 |
59.1 |
In-house |
29-257 (290) |
alignment |
Range on Protein: 17-250
Range on HMM: 29-257/290.0
TYDHTRVVLKGPGGNrdGRSDYINASFLQGFDGTpkKYIAAQGPVEPS-------CDDFWQMVWQERCSVIVMLTGLIEGSKE----KCHKYWPDTNQ-P
.||||||| | .||| |.... .| . |. | | | .|| |. ||. .||| | |.. | || |..
LveatrvvLkgygkr..fnddyiHAnrvtcpngl..rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgee
KPYGQYTVSLCKNEAFADYTVRTFLVTSAPSNEQRfIYQYHFTVWPDKGVPQYATAVLRFRKKIinesRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAK
.. ||. .. |. | .|. .|. .| . . . | . |.. .| .|. . ...| |||| |. | |. |.
lkfkgltvkCkskekeddvetRelvvkfddeeeft.vtHsllkgWnklnvqedtktllsliqkv....kasktpvivHcvdGiSrsAalaaiilgyQkia
-EKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLealvcgstdI
.. | . . . | | | ...... .. |. ... .
etsgsvkledvlkalrkqralaitsalelafvdagiv.........l
|
subfamily_eak_pd |
Subfamily eak |
294-447 |
1.8e-17 |
57.8 |
In-house |
46-197 (332) |
alignment |
Range on Protein: 294-447
Range on HMM: 46-197/332.0
SASRACNASKNrFPDILPLDSHRVALHLSVDKDPGadYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVML-NSLDEEDEHFPRYWPSQ
..| . .| .|.| | . | | | | ||||| | . .||| .. || . ||.||.. .||.| . .... |.. .|.| .
etarleavnrn.vvkivpydrylvrltssqlnrlG..yinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdk
GAE--EYGGIKVELQEEDDKSFFISRRFDItTKGKSTpQRICHFQVTNWSDHSVPDK
. | ..| ..|| .| .. . | . . .|| | |. |..| |.. ..|
treelkfGildverkefvkrniletrllel.skGnet.hrvlhykvfGwtettlpky
|
subfamily_Cele-PTP-1_pd |
Subfamily Cele-PTP-1 |
328-528 |
2e-17 |
58.2 |
In-house |
45-253 (290) |
alignment |
Range on Protein: 328-528
Range on HMM: 45-253/290.0
GADYINASFAHaYRERNAFILTQAPLEDT-------IASFWRMVVDYDLGTIVMLNSLDEEDEHF-----PRYWPSQGAE--EYGGIKVELQEEDDKSFF
||| |.. . . ..||||.|.|.. | .|| |. . .||| .|.... .| | . | ..|..|. .. . .
nddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddv
ISRRFDITTkGKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLNDIQTSQqksgdKAIVVQCSDGVGRSGTLCAIMSVIERVK-VEHVVDVFQAVKNLRIS
. |. .. .. . . | .. .|.. .|..... || |.. ...|. ...| | ||. || .| || . .. | . ...|.||
etRelvvkf.ddeeeftvtHsllkgWnklnvqedtktllsliqkvkask.....tpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkq
RPGAVETLEQYKFCYD
| |. . ... |
ralaitsalelafvda
|
subfamily_eak_pd |
Subfamily eak |
6-166 |
2.1e-17 |
57.5 |
In-house |
52-205 (332) |
alignment |
Range on Protein: 6-166
Range on HMM: 52-205/332.0
NKIKNrYGNIVTYDHTRVVLKGPGGNRDGrsdYINASFLqGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTN-QP
. .| .|| ||. | | ||.| ||||| . | .||| . . | ||||| ... ||.| .| || ||.|| .
avnrn.vvkivpydrylvrltssqlnrlG...yinasla.efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktree
KPYGQYTVSLCKNEAFADYTVRTFLVTSapSNEQRFIYQYHFTVWPDKGVPQYATaVLRFRK
.|.. | . . . .| . .. || .. |.. | . .|.| | .||
lkfGildverkefvkrniletrllelsk..GnethrvlhykvfGwtettlpkyed.flalrk
|
subfamily_Sponge-PTP-4_pd |
Subfamily Sponge-PTP-4 |
318-443 |
9.1e-17 |
55.6 |
In-house |
2-126 (130) |
alignment |
Range on Protein: 318-443
Range on HMM: 2-126/130.0
ALHLSVDKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDEHFPRYWPSQGAEEygGIKVELQEEDDKSFFISRR
||. |.. .| .|||||| . ..|||.|| || ||.|... . .|.| |..||||..| | . || | | | . |. . .
alefevsrlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeedeywpdsePlewyee..diivtltdrdefknikasn
FDITTKGKSTPQRICHFQVTNWS-DHS
..| . . . | . ||..|| | .
leiesdlneshqaltmfqisnwpsdgt
|
subfamily_Cele-PTP-7_pd |
Subfamily Cele-PTP-7 |
351-523 |
3.9e-16 |
53.4 |
In-house |
98-277 (302) |
alignment |
Range on Protein: 351-523
Range on HMM: 98-277/302.0
APLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQGAEE--YG-------GIKVELQEEDDKSFFISRRFDITTKGK--STPQRICHFQVTN
| .|. .| .. .|. . .| | |. |. .. . |. . .| .| .| .|.| || | .|. . | ... . .. .
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WSDHSVPDKPLDLLPLLNDIQtsqqkSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQY
| || |... | .|. . | |...| || ||||.||| || |. . ..| |. . |. .| | ||| . .|
wpdhGapkeaytaldilkfce.....sykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqql
|
subfamily_CG42327_pd |
Subfamily CG42327 |
172-239 |
4e-16 |
53.6 |
In-house |
243-311 (319) |
alignment |
Range on Protein: 172-239
Range on HMM: 243-311/319.0
SRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEK-KVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAV
|.. | .|||| |||||| | | .|. .| . ||| . | | || . |.||.|| ||.. .
tresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
298-406 |
1.4e-15 |
51.9 |
In-house |
45-164 (350) |
alignment |
Range on Protein: 298-406
Range on HMM: 45-164/350.0
ACNASKNRFPDILPLDSHRVALHLSVDK-------DPGADYINASFAHAY----RERNAF--ILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-E
.|||. .||| . || |. |. . |||||.. . . | | ||||| |. |..... . |..|.|..| . |
velfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnle
HFPRYWPSQGaeeYGGIKVELQE
. |||. . | .|.| |..
kcyrYWqegs...ydditvklas
|
subfamily_Cele-PTP-9_pd |
Subfamily Cele-PTP-9 |
342-533 |
2.7e-15 |
51.2 |
In-house |
33-220 (255) |
alignment |
Range on Protein: 342-533
Range on HMM: 33-220/255.0
ERNAFILtqapledTIASFWRMVVDYDLGTIVMLNSLDE-EDEHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITTK-G-KSTPQRICHFQVTN
.| ..| |.. |....| . ..||| . | . |. .|.| . | .|.. . . . | .||.. | | . . |.. .
rknlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykG
WSDHSVPDKPLDLLPLLNDIQTSqqksgdKAIVVQCSDGVGRSGTLCAIMSVIE----RVKVEHV--VDVFQAVKNLRISRPGAVETLEQYKFCYDVTLA
| .. |. . ..| .| .. | |..||.|| |.||| .. . .| .. . .| . ...|| .|..|..| | |. ..|
WieknaPelareilnilkvvrds......ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvld
Y
.
l
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
176-243 |
6.1e-15 |
49.9 |
In-house |
228-295 (297) |
alignment |
Range on Protein: 176-243
Range on HMM: 228-295/297.0
TAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEAL
|. .|||||||||.| . |..| . . |.. |. .. | |. .||| .|. ... |||. |
nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
130-240 |
1.5e-14 |
48.5 |
In-house |
207-341 (350) |
alignment |
Range on Protein: 130-240
Range on HMM: 207-341/350.0
VTSAPSNEQRfIYQYHFTVWPDKG---VPQYATAVLRFRKKIINES-------RHNTAPWIVHCSAGVGRTGAFIVIDAMLRQ-------AKEK------
.| |.|. .|| .. |.| . |. .| ....|.. ...| .||||||||||| .. .| .| . ||
itlaasdPyv.vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldva
-KVVD-IYNYVRATRGDRPNMVQTKDQYVFIHRAVL
|. | | | | | .|||..||..||. |.|
aktrDlisiivnelrkqrismvqnldqfifiYeall
|
subfamily_Sponge-PTP4_pd |
Subfamily Sponge-PTP4 |
3-153 |
1.7e-14 |
48.0 |
In-house |
93-234 (244) |
alignment |
Range on Protein: 3-153
Range on HMM: 93-234/244.0
KPENKIKNRYGNIVTYDHTRVVL-KGPGGNrdgrsDYINASFLqGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLtglieGSKEKCHKYWPDT
.|.| ||| | . .| || | || || ||||||. | | .|| .| |. . |||.|. . |.|.| || |. .||||.
npnnswknregaglpfdfnrvplskgsmgn.....tyinasfv.gclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvl.....gsveeedeywpds
NQPKPYG-QYTVSLCKNEAFADYTVRTFLVTSAPSNEQRFIYQYHFTVWPDKG
. . | . ||.| . | . . . | . . . . . || |
eplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwpsdg
|
subfamily_Cele-PTP-16_pd |
Subfamily Cele-PTP-16 |
6-244 |
2e-14 |
47.9 |
In-house |
47-280 (303) |
alignment |
Range on Protein: 6-244
Range on HMM: 47-280/303.0
NKIKNRYGNIVTYDHTRVVLKgpggnrDgrSDYINASFLQgFDgTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPK
| |||. ... ||..| | | | || ||.|. .| . || | .| |. .. |||||. ... ....| | | . .| ..
nmdknrfvdvicldhskvkls......d..ssyihasyle.ld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdfl
PYGQYTVSLC--KNEAFADYTVRTFLVTsAPSNEQRFIYQYHFTVWPDKGVPQYATAvlRFRKKII---NESR--HNTAPWIVHCSAGVGRTGAFIVID-
. . .. . |. ..| | | . . . |.. .|. || . .| ... .| |.| | .. | . .|.||.|.| ...
kfeersirvgefkrvelgdgwvlkvlsv.sngdyksflhvhhykawphnsipsdgsp..kfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfet
AMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALV
| | .|. .|. . . | | || |. ... . | ..
ahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehvl
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
7-102 |
2.5e-14 |
47.4 |
In-house |
49-157 (349) |
alignment |
Range on Protein: 7-102
Range on HMM: 49-157/349.0
KIKNRYGNIVTYDHTRVVLKG----PGGNRDG--------RSDYINASFLQGFDGT-PKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEGSKEK
|||| .|. |.|.||.|| . . . ||||| .|. . ||||| | |. . |||.... .. ... |. | | ||
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CHKYWPDTN
|..|| . .
cdiywqels
|
subfamily_Sponge-PTP-7_pd |
Subfamily Sponge-PTP-7 |
470-529 |
2.5e-13 |
44.2 |
In-house |
1-60 (69) |
alignment |
Range on Protein: 470-529
Range on HMM: 1-60/69.0
IVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
.||.|| | ||.||. ||| . |.| | .||.| |. .| || | .| | .|
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihda
|
subfamily_Sponge-PTP7_pd |
Subfamily Sponge-PTP7 |
471-529 |
2.9e-13 |
43.9 |
In-house |
1-59 (69) |
alignment |
Range on Protein: 471-529
Range on HMM: 1-59/69.0
VVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
||.|| | ||.||. ||| . |.| | .||.| |. .| || | ..| | .|
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihda
|
subfamily_CG42327_pd |
Subfamily CG42327 |
461-533 |
3.1e-13 |
44.1 |
In-house |
241-314 (319) |
alignment |
Range on Protein: 461-533
Range on HMM: 241-314/319.0
SQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVE-HVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
| ... .|| |||||||.|.. | |.... . ||. | | .| | || | |||.| | | |
sgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
subfamily_Cele-PTP-16_pd |
Subfamily Cele-PTP-16 |
286-529 |
5e-13 |
43.3 |
In-house |
35-274 (303) |
alignment |
Range on Protein: 286-529
Range on HMM: 35-274/303.0
LSPDVRVEsaSRACNASKNRFPDILPLDSHRVALHlsvdkDpgADYINASFAHAYRERNAfILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEE----
| |.| . | |||| |.. || .| | | . || ||. . ...| |||| || | | ||.|... . ...| . |
lppsvskn..qfvknmdknrfvdvicldhskvkls.....d..ssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklg
-DEHFPRYWPSQGAEEYGgIKV-ELQEEDDKSFFISRRFDITTKGKSTPQRICHFqvTNWSDHSVPDK-PLDLLPLLNDIQTSQQKSGDKAIVVQC-SDG
| ||| || |.| |... . . . .. . . |. .| |.| . .. . ..|. .| | | |
gdsvfprnqdflkfeers.irvgefkrvelgdgwvlkvlsvsngdyksflhvhhy..kawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsg
VGRSGTLCAIMSVIERVKVE-HVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
.||.||.. . . .. | .|. . ..|.| | ||. | |. . | .
cgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytl
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
468-534 |
1e-12 |
42.5 |
In-house |
229-295 (297) |
alignment |
Range on Protein: 468-534
Range on HMM: 229-295/297.0
KAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCYDVTLAYL
..| || |||||| . . ...... ... || .. || |. |.||||....||..|. |
ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
424-533 |
1.2e-12 |
42.3 |
In-house |
210-343 (350) |
alignment |
Range on Protein: 424-533
Range on HMM: 210-343/350.0
GKSTPQRICHFQVTNWSDHSVPDKPLDLLPLLN------DIQTS---QQKSGDKAIVVQCSDGVGRSGTLCAIMSVIE-----------RVKVEH---VV
| | . ..|| || | |. .| ..|. |. | .. ... ..|.| || |||| |||... |... .|.. .
aasdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktr
D-VFQAVKNLRISRPGAVETLEQYKFCYDVTLAY
| ... |..|| | | .|.|. |.|. | |
DlisiivnelrkqrismvqnldqfifiYeallfy
|
subfamily_hpo-7_pd |
Subfamily hpo-7 |
342-532 |
3e-12 |
41.0 |
In-house |
36-225 (263) |
alignment |
Range on Protein: 342-532
Range on HMM: 36-225/263.0
ERNAFILtqapLEDTIASFWRMVVDYDLGTIVMLNSLDEE-DEHFPRYWPSQGAEEYGGIKVELQEEDDKSFFISRRFDITT--KGKSTPQRICHFQVTN
.| ..| | .||..|....| ..||| || |. .|.| . | .|.. . .| . . ... . | . . . |.. .
rknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykg
WSDHSVPDKPLDLLPLLNdIqtsQQKSgdKAIVVQCSDGVGRSGTLCAIMSVIE----RVKVEHV--VDVFQAVKNLRISRPGAVETLEQYKFCYDVTLA
| .. | .. . | .|. . ..| | .|| || |.||| . .| .. . .| . ...|| ||..|..| | | ..|
Wiekndpelareilnilk.v...arns..kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLd
|
subfamily_Cele-PTP-12_pd |
Subfamily Cele-PTP-12 |
300-383 |
3.6e-10 |
33.8 |
In-house |
34-115 (332) |
alignment |
Range on Protein: 300-383
Range on HMM: 34-115/332.0
NASKNRFPDILPLDSHRVALHLSVDKDpgaDYINASFAHAYRERNAFILTQAPLEDT-IASFWRMVVDYDLGTIVMLNSLDEEDE
| || | . .| || | || |. |||. | ...|.|..|||..| ||||| . |... .||...
nmdmnriphlycfdhsrvelapqdgkd...dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqk
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
2-49 |
1.1e-09 |
32.2 |
In-house |
43-88 (440) |
alignment |
Range on Protein: 2-49
Range on HMM: 43-88/440.0
KKPENKIKNRYGNIVTYDHTRVVLKGPGGNRDgrSDYINASFLQGFDG
|.||.|||| ||..|||.||.|. | | |||||||...| .
slpnnkvknryrnilaydhsrvmleevkgvpd..sdyinasyingies
|
subfamily_Sponge-PTP-4_pd |
Subfamily Sponge-PTP-4 |
35-153 |
1.2e-09 |
32.5 |
In-house |
12-125 (130) |
alignment |
Range on Protein: 35-153
Range on HMM: 12-125/130.0
RSDYINASFLqGFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVMLtglieGSKEKCHKYWPDTNQPKPYG-QYTVSLCKNEAFADYTVRTFLVTSA
.||||||. | | ..|. .| |. .. |||.|. . |.|.| || |. .||||.. . | . .|.| . . | . . |
gntyinasfv.Gllgrtaeylltqhpladtsmdfwkmmleryvnvlvvl.....gsveeedeywpdsePlewyeediivtltdrdefknikasnleiesd
PSNEQRFIYQYHFTVWPDKG
. .. . .. . || |
lneshqaltmfqisnwpsdg
|
subfamily_Cele-PTP-17_pd |
Subfamily Cele-PTP-17 |
7-83 |
1.5e-09 |
31.9 |
In-house |
38-116 (347) |
alignment |
Range on Protein: 7-83
Range on HMM: 38-116/347.0
KIKNRYGNIVTYDHTRVVLKgPGGNRDGRSD----YINASFLQgFDGTPKKYIAAQGPVEPSCDDFWQMVWQERCSVIVML
||| . | ||||| | . .|.| ||||| .. || . |.|| .| |. . |||.|| . . .| .
lsknrskdvklidatrvvls.peksknsraddvetyinashik.fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
subfamily_Sponge-PTP3_pd |
Subfamily Sponge-PTP3 |
292-350 |
5.1e-09 |
30.2 |
In-house |
40-94 (95) |
alignment |
Range on Protein: 292-350
Range on HMM: 40-94/95.0
VESASRACNASKNRFPDILPLDSHRVALHLSVDkdpgADYINASFAHAYRERNAFILTQ
| .| |||| .|.| |. ||.| | .||||| | | .|..| .|
ytvgsseanipknrflnifpydatrvvlttkrd....sdyinacfvdgyarkncyiaaq
|
subfamily_Cele-PTP-17_pd |
Subfamily Cele-PTP-17 |
299-374 |
5.6e-09 |
30.0 |
In-house |
36-115 (347) |
alignment |
Range on Protein: 299-374
Range on HMM: 36-115/347.0
CNASKNRFPDILPLDSHRVALHLSV----DKDPGADYINASFAHAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVM
. |||| | |. || | |. ||||| . .. .|||| || ||. ||.|| . .|
kslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
subfamily_Sponge-PTP3_pd |
Subfamily Sponge-PTP3 |
6-59 |
1.1e-08 |
29.1 |
In-house |
48-95 (95) |
alignment |
Range on Protein: 6-59
Range on HMM: 48-95/95.0
NKIKNRYGNIVTYDHTRVVLKgpgGNRDgrSDYINASFLQGFDGtPKKYIAAQG
| |||. ||. || ||||| .|| |||||| |..|. . ||||||
nipknrflnifpydatrvvlt...tkrd..sdyinacfvdgyar.kncyiaaqg
|
0038934 |
(Phosphotyrosine protein) phosphatases II |
129-236 |
1.2e-08 |
30.4 |
In-house |
21-170 (194) |
alignment |
Range on Protein: 129-236
Range on HMM: 21-170/194.0
LVTSAPSNEQR-------------------------------------------F---IYQYHFTVWPDKGV-P--QYATAVLRFRKKIINESRHNTApw
.... |... | ..|. .||.|. | . . |.. ....||. ...
iafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvv..
IVHCSAGVGRTGAFIVIDAMLRQAKekKVVDIYNYVRATRgdrPNMVQTKDQYVFIH
||| ||.|||| ... . |. .. . ....| | |..... |.. ..
aVHCkaGlgRtGtlvaaYLiyrlgm..saeeAialfrekR...pgaipnqdyleall
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
140-240 |
1.2e-08 |
28.7 |
In-house |
219-341 (349) |
alignment |
Range on Protein: 140-240
Range on HMM: 219-341/349.0
FIYQYHFTVWPDKGV---PQYATAVLRFRKKIINES-------RHNTAPWIVHCSAGVGRTGAFIVIDAMLR--QAKEKKV----------VDIYNYVRA
..| . |.| .. |. | ....|.. .... .|||||| |||| .. .| .| . ... |. |
ellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivne
TRGDRPNMVQTKDQYVFIHRAVL
| | .||| |...|. |.|
lrkqrismvqnlaqfiaiyealL
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
46-128 |
1.4e-08 |
28.5 |
In-house |
228-309 (440) |
alignment |
Range on Protein: 46-128
Range on HMM: 228-309/440.0
GFDGTPKK--YIAAQGPVEPSCDDFWQMVWQERCSVIVMLTGLIEgskEKCHKYWPDTNQPKPYGQYTVSLCKNEAFADYTVRTF
|.| || .||.| |.. . |||..| . | | |.|| | . | ||| . .| .|| | . |||.
efegyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtl
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
300-408 |
3e-08 |
27.4 |
In-house |
48-169 (349) |
alignment |
Range on Protein: 300-408
Range on HMM: 48-169/349.0
NASKNRFPDILPLDSHRVALHLSVDKDPG-------------ADYINASFAHAYR--ERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEED-E
.|||. |||| . || |. |. . ||||| . . | . .| ||||| |. |..... . .. ||. .|.. |
lfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
HFPRYWPSQgaeEYGGIKVELQEED
. .|| .| .|.| ||.
kcdiywqel...sysnitvklqnss
|
subfamily_Cele-PTP-12_pd |
Subfamily Cele-PTP-12 |
8-93 |
3.3e-08 |
27.4 |
In-house |
36-117 (332) |
alignment |
Range on Protein: 8-93
Range on HMM: 36-117/332.0
IKNRYGNIVTYDHTRVVLKgpggNRDGRSDYINASFLQGFDGTpKKYIAAQGPVEPSCDD-FWQMVWQERCSVIVMLTGLIEGSKEK
|| . .||.|| | .||. |. |||...|. || || |.. . ||.|| . . |.|... . | | |
dmnriphlycfdhsrvela....pqdgkddfynaswvdgyskk.sayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
subfamily_DSP23_pd |
Subfamily DSP23 |
466-528 |
4.6e-08 |
27.8 |
In-house |
83-140 (148) |
alignment |
Range on Protein: 466-528
Range on HMM: 83-140/148.0
GDKAIVVQCSDGVGRSGTLCAIMSVIERvkveHvVDVFQAVKNLRISRPGAVETLEQYKFCYD
..|. | | | ||.||. | | || . . .|. ..| |||.|||.|| | .|
kneavsvhcllgrgrtgtmlacylvker....k.laaaeaiaevrrlrpgsvetveqeklvrd
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
425-534 |
6.4e-08 |
26.3 |
In-house |
214-344 (349) |
alignment |
Range on Protein: 425-534
Range on HMM: 214-344/349.0
KSTPQRICHFQVTNWSDHSVPDKPLDLLPLLN---D---IQT---SQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIE--------RVKVEH---VVD-VF
.. | . .|| || | |. | .| |. | . ... ...| || | ||.|.|. . .... .|.. | ..
vekPyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlis
QAVKNLRISRPGAVETLEQYKFCYDVTLAYL
.| .|| | |. | |. ..|. | |.
iivnelrkqrismvqnlaqfiaiyealLkyf
|
subfamily_PTPDC1_pd |
Subfamily PTPDC1 |
139-236 |
7e-08 |
27.1 |
In-house |
81-169 (182) |
alignment |
Range on Protein: 139-236
Range on HMM: 81-169/182.0
RFIYQYHFTvWPDKGVPQYATaVLRFRkKIINESRHNTaPWIVHCSAGVGRTGAFIVidAMLRQAKEkkvVDIYNYVRATRGDRPNMVQTKDQYVFIH
. || | |. |.| ||. . .| |... . .. ||| || |||| | ..| ||. .. . .. | ||. .||..| ...
qgiyvynfg.wkDygvasler.iLdiv.kvvafalqeg.kvavhChaGlGrtGvlia..cylvyakr...ltaekaiklvrskrpksiqtreqvelvk
|
subfamily_Cele-PTP-5_pd |
Subfamily Cele-PTP-5 |
423-534 |
1e-07 |
24.9 |
In-house |
199-309 (346) |
alignment |
Range on Protein: 423-534
Range on HMM: 199-309/346.0
KGKSTpQRICHF-QVTNWSDHSVPDKPLDLLPLLNDIQTSQQKSgDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLE
.|.| ||. . . | | | | .. .. .. . .| . . | | ||. .. . |... .... .||.. |||.||..
egnsd.svicqvhhhapwkhlqqppktlpiikmihqflsekqvq.nagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfa
QYKFCYDVTLAYL
|| | . . |.
qyasiyaivfdyi
|
subfamily_eak_pd |
Subfamily eak |
176-245 |
2.4e-07 |
24.5 |
In-house |
237-307 (332) |
alignment |
Range on Protein: 176-245
Range on HMM: 237-307/332.0
TAPwIVHCSAGVGRTGAFIVIDAMLRQ--AKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALVC
|| |. .. | |.|.|.||| ..| .| | . . ... . | | .. |. ||. .||. |
fap.iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllr
|
PTPc_motif_SM00404 |
|
165-222 |
2.6e-07 |
25.6 |
In-house |
69-125 (140) |
alignment |
Range on Protein: 165-222
Range on HMM: 69-125/140.0
RKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMlrQAKEKKVVDIYNYVRATRGD-R
...|.... . .||| ||| |....|. | . .. .. . |..|. | .
vldfienaekkggkvlVHCqaGvSRSatliiaYlm..ryrqlslaeayefvkerRpiis
|
0038934 |
(Phosphotyrosine protein) phosphatases II |
437-527 |
6.1e-07 |
24.8 |
In-house |
86-170 (194) |
alignment |
Range on Protein: 437-527
Range on HMM: 86-170/194.0
TNWSDHSVPDKPlDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSvIERvkvEHVvDVFQAVKNLRISRPGAVETLEQYKFCY
.|..||. || |. ... ... .....| | |.||.|||.| |.| . .. .|.. .|. ||||... .... .
pfpddgtvPsle.illrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYL.iyr...lgm.saeeAialfrekRpgaipnqdyleall
|
subfamily_Cele-PTP-5_pd |
Subfamily Cele-PTP-5 |
62-244 |
6.6e-07 |
22.2 |
In-house |
128-310 (346) |
alignment |
Range on Protein: 62-244
Range on HMM: 128-310/346.0
EPSCDDFWQMVWQERCSVIVMLTgLIEGSKEKCHKYWPDTNQPKpygQYTVSLCKNEAFADYTV--RTFLVTSAP-SNEQRFIYQY-HFTVWPDKGVPQY
| .||| |..||. .. .. . |. . | | ||| . |. || . . . . | | . | | | . | |
esfvedfwymiyqeqihlvylmv.pddklkntttslfndenggy...qytgkmfinnrradvsgdpkeytievlpegnsdsvicqvhhhapwkhlqqppk
ATAVLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKVVDIYNYVRATRGDRPNMVQTKDQYVFIHRAVLEALV
. .... ... | . ..| | | ||. .|| ..| . .|.. ... . .|| |.. || |. |.. .
tlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyia
|
PTEN_1 |
|
436-525 |
7.4e-07 |
24.2 |
In-house |
99-184 (196) |
alignment |
Range on Protein: 436-525
Range on HMM: 99-184/196.0
VTNWSDHSVPDKPLDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERVkvehvVDVFQAVKNLRISR-PGAVETLEQYKF
. || .|. . . . |. .... ....| | |.|||||..| . . .. .|.. .|. | |||... .| ..
hfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk.....ltadeAlelvrekRppgapnspsqerl
|
subfamily_DSP19_pd |
Subfamily DSP19 |
166-224 |
8.4e-07 |
23.4 |
In-house |
79-136 (152) |
alignment |
Range on Protein: 166-224
Range on HMM: 79-136/152.0
KKIINESRHNTAPWIVHCSAGVGRTGAfIVIDAMLRqAKEKKVVDIYNYVRATR-GDRPN
. |.|.|.. .|||.||| |. . .|| ... .|... . ...||..| .||
ldFieearskdgavlvHCnAGvSRsas.vviaylmk.keelsleealelvrearpcikPn
|
DSPc |
Dual specificity phosphatase, catalytic domain |
161-224 |
9.7e-07 |
23.7 |
Pfam-A |
58-120 (133) |
alignment |
Range on Protein: 161-224
Range on HMM: 58-120/133.0
VLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMlrQAKEKKVVDIYNYVRATRGD-RPN
|. ...|.. . . .||| ||. |....|. | . |. .. . |..|. |. .||
eleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlm..ktknlslneAyefvkerrskispn
|
DSPc |
Dual specificity phosphatase, catalytic domain |
161-224 |
9.7e-07 |
23.7 |
In-house |
58-120 (133) |
alignment |
Range on Protein: 161-224
Range on HMM: 58-120/133.0
VLRFRKKIINESRHNTAPWIVHCSAGVGRTGAFIVIDAMlrQAKEKKVVDIYNYVRATRGD-RPN
|. ...|.. . . .||| ||. |....|. | . |. .. . |..|. |. .||
eleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlm..ktknlslneAyefvkerrskispn
|
subfamily_DSP10_pd |
Subfamily DSP10 |
168-220 |
9.9e-07 |
22.8 |
In-house |
84-134 (159) |
alignment |
Range on Protein: 168-220
Range on HMM: 84-134/159.0
IINESRHNTAPWIVHCSAGVGRTGAFIVidAMLRQAKEKKVVDIYNYVRATRG
|.| |.. . .||| ||. | .... | | . .. .. | |..|. .|
fieearkkgsrvLvhCqaGisrsatvvi..aYlmkhlnlslndaykfvkekrp
|
subfamily_Sponge-PTP-2_pd |
Subfamily Sponge-PTP-2 |
6-115 |
3.2e-06 |
20.1 |
In-house |
27-107 (169) |
alignment |
Range on Protein: 6-115
Range on HMM: 27-107/169.0
NKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINAsflqgfdgtpkkyiaaqgpvepscddfwQMVWQERCSVIVMLtglieGSKEKCHKYWPDTNQ--
|. ||| .. |||| |. | |||||| .|.|. ||||.| | . .||. ..
netknrpagplapshtrvklqrv..medlgsdyina............................rmiwetnasvivvl.....gdtddknnfwpekedyq
PKPY---G-QYTVSLC
.| | || ||
lhpavilgewytdsly
|
PTEN_1 |
|
143-225 |
3.4e-06 |
22.0 |
In-house |
96-178 (196) |
alignment |
Range on Protein: 143-225
Range on HMM: 96-178/196.0
QYHFTVWPDKGVPQYAtAVLRFRKKIINESR-HN-TAPWIVHCSAGVGRTGafIVIDAMLRQAKEKKVVDIYNYVRATR-GDRPNM
.|. ..| |.| . .... |..|. . .. .||| ||.||.| |. | | ... . . .||. | .||.
eylhfpieDhgapsls.elfdicksfiewllsdpngnvVlVHCkaGlgRsG..tvvaayLmykgkltadeAlelvrekRppgapns
|
subfamily_Sponge-PTP2_pd |
Subfamily Sponge-PTP2 |
6-114 |
4.3e-06 |
19.7 |
In-house |
26-105 (169) |
alignment |
Range on Protein: 6-114
Range on HMM: 26-105/169.0
NKIKNRYGNIVTYDHTRVVLKGPggNRDGRSDYINAsflqgfdgtpkkyiaaqgpvepscddfwQMVWQERCSVIVMLtglieGSKEKCHKYWPDTNQ--
|. ||| .. |||| |. | |||||| .|.|. ||||.| | . .||. ..
netknrpagplapshtrvklqrv..medlgsdyina............................rmiwetnasvivvl.....Gdtddknnfwpekedyq
PKPY---G-QYTVSL
.| | || ||
lhpavilGewytdsl
|
subfamily_Cele-PTP-12_pd |
Subfamily Cele-PTP-12 |
387-527 |
4.4e-06 |
20.4 |
In-house |
152-295 (332) |
alignment |
Range on Protein: 387-527
Range on HMM: 152-295/332.0
RYWPSQGAEEYGgIKVELQEEDDKSFFISRRFDITTKGKSTPQRICHFQVTNWSDHS-VPDKPLDLLPL--LNDIQTSqQKSGD--KAIVVQCSDGVGRS
..|| ..... . .| ||.| . |..| | .. ... .|.| | .|. ||. |. |..| .|.| |.. |. || .
kfwpekrskkdf.palsiqasddhsethmktfnltvtekkqdhqtvlmhfyewadasklpeymldmrasiklqyirss.kktgvcigpimlvcatgvekc
GTLCAIMSVIERVKVEHVVDVFQAVKNLRISRPGAVETLEQYKFCY
..| .. |. || | . ... ... | |.. |. | .
aisatidiivsriteehrvgfketmsaikmqrfgcfrtvgpystac
|
subfamily_DSP6_pd |
Subfamily DSP6 |
167-221 |
8.4e-06 |
19.4 |
In-house |
84-136 (158) |
alignment |
Range on Protein: 167-221
Range on HMM: 84-136/158.0
KIINESRHNTAPWIVHCSAGVGRTGAFIVidAMLRQAKEKKVVDIYNYVRATRGD
. |.|.|.. . .||| ||. |. . .. | | . .. . | |..|.. . .
efidearskkskvlvhClaGisrsvtvtl..aylmkklalslndaydlvkkrksn
|
subfamily_PTPDC1_pd |
Subfamily PTPDC1 |
435-529 |
8.6e-06 |
20.3 |
In-house |
86-171 (182) |
alignment |
Range on Protein: 435-529
Range on HMM: 86-171/182.0
QVTNWSDHSVPDkPLDLLPLLNdIQTSQQKSGdkAIVVQCSDGVGRSGTLCAIMSVIErvkveHVVDVFQAVKNLRISRPGAVETLEQYKFCYDV
|.|..|. .| . . .. . | .. | | | || | | | . | . .. .|.| .| || ...| || ... .
ynfgwkDygvas.leriLdivk.vvafalqeg..kvavhChaGlGrtGvliacylvya.....krltaekaiklvrskrpksiqtreqvelvkef
|