Gene PTPN14 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPN14
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP074_AA protein Get Run
NvecP074_AA_1-122 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTPN14_pd Subfamily PTPN14 1-125 5.9e-65 214.2 In-house 177-300 (300) alignment
Range on Protein: 1-125
Range on HMM: 177-300/300.0
MPTKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRSSvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQR
.|.|..|||.|.|.||||||.||.|...||..|..|.|.|..|.....| .||||||||||.||||||||.||.||.||....|..|.|...| |||.||
lpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves.keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqr

MLLVANFGQYRFVYSTVIHYIKNSR
||||....||.|||...|.|.||||
mllvqtlaqYkfvYkvlikylknsr

0050432 (Phosphotyrosine protein) phosphatases II 3-123 4.7e-38 126.6 In-house 193-301 (308) alignment
Range on Protein: 3-123
Range on HMM: 193-301/308.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttRSsvheskPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.| ..|.|||| ||..|...|.||..|.. .      ..      .|..||| |||||||..|. ||.. ... ...... .|. .||.||. 
dgesrtvthfhytnWpdhgvPpspeilldflelvrksl......pg......gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpg

LVANFGQYRFVYSTVIHYIKN
 | .. ||.|.| ....|.|.
mvqtpeqylflyralleylkl

0046845 (Phosphotyrosine protein) phosphatases II 3-123 7.4e-38 125.9 In-house 161-276 (284) alignment
Range on Protein: 3-123
Range on HMM: 161-276/284.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNK---RINIHHALVRLRRQ
|.. |||.| ..|.|||| ||..|...||||..|..|...        .....|..||| |||||||..|. ||.. ......   .... .|. |||.|
tgesrtvthfhytswpdhgvppspedlleflrlvrellen........lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreq

RMLLVANFGQYRFVYSTVIHYIKN
|.  | .. |||||| ....|.|.
Rpgmvqtleqyrfvyealleylkl

0036941 (Phosphotyrosine protein) phosphatases II 3-123 1.4e-37 125.0 In-house 164-279 (297) alignment
Range on Protein: 3-123
Range on HMM: 164-279/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQ---NNKRINIHHALVRLRRQ
....|||.| ..|.|||| ||..|.|.|.|...|.. .. .         |..|||||| |||||.|..|. |||. ...    .....|  |.  ||.|
ngesrtvthfhytgwpdhgvpespaslldfielvrkvlkll........psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReq

RMLLVANFGQYRFVYSTVIHYIKN
|.  | ...||||.| ......|.
Rpgavqtleqyrflyeallellkk

0051299 (Phosphotyrosine protein) phosphatases II 3-122 1.7e-37 124.9 In-house 178-287 (288) alignment
Range on Protein: 3-122
Range on HMM: 178-287/288.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.| ..|.|||| |||.|...|.|| .| . ..           ...||.||| |||||||..|. ||.. .......... .|. |||.||. 
dgesrtvthfhytnwpdhgvpdspellldflrlvrkala..........sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpg

LVANFGQYRFVYSTVIHYIK
.| .. |||||| ....|.|
mvqtpeqyrfvyealleylk

0039614 (Phosphotyrosine protein) phosphatases II 3-123 1.9e-37 124.7 In-house 179-291 (297) alignment
Range on Protein: 3-123
Range on HMM: 179-291/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.|.|.|.|||| ||......||||..|.. ....        ... ||||||.|||||||..|. .||. ... ...... .|. .||.||. 
ngesrtvthfqytgwpdhgvppslellleflelvrealael........pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpg

LVANFGQYRFVYSTVIHYIKN
 | ...||||.|  .....|.
avqtpsqyrflydallellkr

0045450 (Phosphotyrosine protein) phosphatases II 3-123 7.2e-37 123.2 In-house 191-306 (307) alignment
Range on Protein: 3-123
Range on HMM: 191-306/307.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR---INIHHALVRLRRQ
|.. |||.| ..|.|||| ||... ..|.|...|.. ...        . .. ||||||.|||||||..|. .||. ......    ... .|. .||.|
tgesrtvthfhytgwpdhgvppsfeelldfieevrkalee........lpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreq

RMLLVANFGQYRFVYSTVIHYIKN
|.  | |..||||.|  .......
Rpgavqnpeqyrflyeallelllk

0040438 (Phosphotyrosine protein) phosphatases II 3-123 1e-36 122.2 In-house 168-278 (317) alignment
Range on Protein: 3-123
Range on HMM: 168-278/317.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
....|||.| ..|.|||| ||..|...|.||..|.. ..          ... ||||||.|||||||..|. .||. ... ...... .|. .||.||. 
dsesrtvthfhytgWpdhgvppspdllldfleavreale..........dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpg

LVANFGQYRFVYSTVIHYIKN
 | ...||||.|  ...|.|.
avqtpeqyrflydalleylkr

0047943 (Phosphotyrosine protein) phosphatases II 3-122 2.3e-36 121.1 In-house 162-273 (273) alignment
Range on Protein: 3-122
Range on HMM: 162-273/273.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheskPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|.. |||.|...|.|||| ||....|.|||...|.. .. .           .||.||| |||||||..|. ||.. ... ......  |. .||.||. 
tgesrtvthfhytgwpdhgvppslesllefielvrkalealpsn........gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpg

LVANFGQYRFVYSTVIHYIK
 | .. ||||.| ....|.|
mvqtpeqyrflyealleylk

0040439 (Phosphotyrosine protein) phosphatases II 3-123 2.6e-35 117.6 In-house 136-248 (249) alignment
Range on Protein: 3-123
Range on HMM: 136-248/249.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.|.|.|||||| ||... ..|.|...|.. ....        ... ||||||.|||||||..|. .||. ... ...... .|.  ||.||. 
dgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel........pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpg

LVANFGQYRFVYSTVIHYIKN
 | |..||||.|  .......
avqnpeqyrflyeallelllk

DSPc_SM00195 4-122 2.7e-35 117.3 In-house 155-263 (263) alignment
Range on Protein: 4-122
Range on HMM: 155-263/263.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|...|...|||| |||...|.||.| .|.. ....          ..|..||| |||||||.....|...  ....|...| . . .|| ||. .
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..........sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm

VANFGQYRFVYSTVIHYIK
| .. ||.|.| ....|||
vqtleqYlfiyeaileyik

PTPc_SM00194 4-122 2.7e-35 117.3 In-house 155-263 (263) alignment
Range on Protein: 4-122
Range on HMM: 155-263/263.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|...|...|||| |||...|.||.| .|.. ....          ..|..||| |||||||.....|...  ....|...| . . .|| ||. .
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..........sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm

VANFGQYRFVYSTVIHYIK
| .. ||.|.| ....|||
vqtleqYlfiyeaileyik

0043336 (Phosphotyrosine protein) phosphatases II 3-122 4.2e-35 117.0 In-house 169-278 (278) alignment
Range on Protein: 3-122
Range on HMM: 169-278/278.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.|.....|||| ||......|.|| .| . ..           |. ||||||.|||||||..|. .|.. ............|. .||.||. 
dgesrtvthyhylgwpdhgvpeslsllldflkavreale..........dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpg

LVANFGQYRFVYSTVIHYIK
 | .. ||||.|  ...|.|
avqtpsqyrflyealleylk

0042113 (Phosphotyrosine protein) phosphatases II 3-122 1e-34 115.4 In-house 134-244 (245) alignment
Range on Protein: 3-122
Range on HMM: 134-244/245.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
....|.|.|.....|||| |||.. ..|.||. |.. ...          |. ||||||.|||||||..|. .||. ... ...... .|. .||.||. 
ddesrevihyhylpwpdhgvpdllellldflefvrkalae.........dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpg

LVANFGQYRFVYSTVIHYIK
 | ...||||.|  .....|
avqtpsqyrflyeallellk

0045098 (Phosphotyrosine protein) phosphatases II 3-122 1.7e-34 114.9 In-house 150-273 (278) alignment
Range on Protein: 3-122
Range on HMM: 150-273/278.0
TKQQRTVYHVQFTDWPDHRVPDDP--TSFLEFLDQVESLRQRTSTTRSS---VHESKPPVLVHCTAGVGRTGVIILTDLMIACIqnNKRINIHHALVRLR
. ..|.|.|.... |||| ||..|  .||||.|..... ...  .  .|   ...|. |||||| |||||||.... .||. ..  ...... .|.  ||
dlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelr

RQRML-LVANFGQYRFVYSTVIHYIK
.||.   | |..||||.|  ......
sqRpglavqnleqyrflyefllelll

subfamily_PTPN3_pd Subfamily PTPN3 3-121 1.8e-34 114.0 In-house 167-275 (280) alignment
Range on Protein: 3-121
Range on HMM: 167-275/280.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
||..|.. ..|...|||| ||||...||||...|..||          . .. ||.|||.||.|||||.|| .. .| |.... ... . . ..| ||. 
tkeerkilqlqylaWpdhgvPddsadflefvervrklr..........sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqram

LVANFGQYRFVYSTVIHYI
|| . .||.||  ....  
lvqtasqykfvCeailkvy

subfamily_PTPRD_pd Subfamily PTPRD 4-123 1.9e-34 114.3 In-house 174-283 (564) alignment
Range on Protein: 4-123
Range on HMM: 174-283/564.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| . .||.|||| ||. .||.|.....|..|..          . . |..||| |||||||. |  | |.  |...| ..|   . .||.||  .
sesreVrqFhFtsWPdhgvpesatslLdlirkvralne..........pdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnam

VANFGQYRFVYSTVIHYIKN
| .  || |..... .... 
VqteeQYiFiheailealac

0037934 (Phosphotyrosine protein) phosphatases II 3-121 7.5e-33 109.5 In-house 129-242 (243) alignment
Range on Protein: 3-121
Range on HMM: 129-242/243.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIqnnkRINIHHALVRLRRQRML
....|.|.|.... |||| |||.|...|.|||.| .  ... . .  .  |. ||||||.|||||||..|. .||. ..    .... .|. .||.||. 
ddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsll..aldsggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpg

-LVANFGQYRFVYSTVIHYI
  | ...||||.|  .....
kavqtpsqyrflyeallell

Y_phosphatase Protein-tyrosine phosphatase 5-118 9.9e-33 108.9 Pfam-A 131-234 (235) alignment
Range on Protein: 5-118
Range on HMM: 131-234/235.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..|.|.....|.|||| ||..|.|.|.....||. .          .... ||.||| |||||||.... |... ...... ... ... .||.||. .|
ekrevkqlhytnWpdhgvpespkslldlirkveksk..........eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv

ANFGQYRFVYSTVI
 .. || |.| ...
qsleqYiflykail

Y_phosphatase Protein-tyrosine phosphatase 5-118 9.9e-33 108.9 In-house 131-234 (235) alignment
Range on Protein: 5-118
Range on HMM: 131-234/235.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..|.|.....|.|||| ||..|.|.|.....||. .          .... ||.||| |||||||.... |... ...... ... ... .||.||. .|
ekrevkqlhytnWpdhgvpespkslldlirkveksk..........eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv

ANFGQYRFVYSTVI
 .. || |.| ...
qsleqYiflykail

subfamily_PTPN6_pd Subfamily PTPN6 4-125 2.4e-32 107.2 In-house 183-301 (306) alignment
Range on Protein: 4-125
Range on HMM: 183-301/306.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNN---KRINIHHALVRLRRQR
|..|.|.. .|..|||| || ||  .|.||..|.. .......      .. |..|||.||.|||| .|..|...  |...     |.|...   .|.||
keerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea......eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqr

MLLVANFGQYRFVYSTVIHYIKNSR
  ||    ||.||| .. .||....
sglvqteqqykfvykaikkyietkk

PTPc_DSPc_SM00012 8-118 1e-31 104.6 In-house 1-104 (105) alignment
Range on Protein: 8-118
Range on HMM: 1-104/105.0
TVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTtrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNN-KRINIHHALVRLRRQRMLLVAN
||.|...|.|||| ||....|.||.|..|.. ..  ..        ..||.||| |||||||.... |...  .... |...|   . .||.||. .| .
tvkhyhytgwpdhgvPeesdsilellravkknknkses........skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqt

FGQYRFVYSTVI
. || |.|  ..
eeqylflyrall

subfamily_PTPN9_pd Subfamily PTPN9 3-124 2.5e-30 100.6 In-house 169-293 (297) alignment
Range on Protein: 3-124
Range on HMM: 169-293/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQR---TSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQ
|...|.| | ||. |||. ||.. .|.|..|..| . .     . . ..  | |.||..|||.||.||||  |  |. .. ...   ... ... .|| |
teesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtq

RMLLVANFGQYRFVYSTVIHYIKNS
|   .    || | | .|. | ...
rafsiqtpeqyefcylavleyalel

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 4-122 1.2e-29 98.5 In-house 175-284 (305) alignment
Range on Protein: 4-122
Range on HMM: 175-284/305.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..||| . |.|||||| ||. .||.|.....|.  ...         . . |.|||| |||||||| |  |...  ... . ... . | .||..|| .
kesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk.........dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkm

VANFGQYRFVYSTVIHYIK
| .  || |..  .  .|.
vqtldqYvflhdaldelit

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 5-123 1.5e-29 97.8 In-house 150-266 (270) alignment
Range on Protein: 5-123
Range on HMM: 150-266/270.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsTTRSSVHESKpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| . | ....|||| || .. | |.  . .. ||.    .... .... |.||||.|||||||..|..| .. .....|.... . . .||..|| ||
eerrlvHfwyntWpdhgvpreedsslstdqllkmlravr.rsekeldkae.PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalv

ANFGQYRFVYSTVIHYIKN
    ||.|.| .|..|.. 
qhpeqyeflykavveyaer

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 3-122 4.6e-29 96.4 In-house 171-280 (288) alignment
Range on Protein: 3-122
Range on HMM: 171-280/288.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
.|..... . |.. |||| ||.. . .||.|.||.   |              |..|||.|||||||. |  | .|  ..... |..  .. .||.||.|
kkteleitqyqylaWpdhgvPeskapllellrqvkvanqad..........tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRal

LVANFGQYRFVYSTVIHYIK
|| .  || |.|..... |.
lvqtlkqYefiyevllslie

subfamily_Ptp69D_pd Subfamily Ptp69D 5-122 5.3e-29 96.3 In-house 180-287 (307) alignment
Range on Protein: 5-122
Range on HMM: 180-287/307.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| |   ..| |.|  ||. ... |....||..| .            . |..||| |||||.|...  |...  ........| .    ||.|| |||
dsrkvvqyhytgWkDskvPevargllklieqvrelykln..........rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllv

ANFGQYRFVYSTVIHYIK
 .. || |.|  .. |..
qsleqYvflyralldyss

0043147 (Phosphotyrosine protein) phosphatases II 3-114 6.4e-29 96.3 In-house 59-154 (172) alignment
Range on Protein: 3-114
Range on HMM: 59-154/172.0
TKQQRTVYHVQFTDWPDHRVPdDPTSFLEFLDQVES--LRQRtsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIaciqnnKRINIHHALVRLRRQR
.. .|........ |||| || ..  .||||.....  ....           . ||||||.|||||||.... .||.      .......|.  .|..|
ellerlgiqylylpwpDhgvp.llellleflefidellalsp...........ggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekR

MLLVANFGQYRFVY
.  | |..||||.|
pgavqnpsqyrfly

subfamily_PTPRB_pd Subfamily PTPRB 4-124 7.4e-29 95.7 In-house 176-288 (293) alignment
Range on Protein: 4-124
Range on HMM: 176-288/293.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..|.| . .|| |||| ||......|.|. .|..  ..|.        || |..||| |||||||. |  | ..  |...  ..|   ...||..|.||
keerkvrqyhftsWpdhgvPektktlldfvrtvreaiekta........skrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnll

VANFGQYRFVYSTVIHYIKNS
| .  || |....|.......
vqtekqYifihqcvldllrkk

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 4-123 1.8e-28 94.4 In-house 158-270 (274) alignment
Range on Protein: 4-123
Range on HMM: 158-270/274.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|.|  .||||||..|||....|.....|       ...|.. ..   ||.|||.||.||||. | ... .  ..... ... .  . || .|  .
erersvkhywytdWPdhksPddantlldlvlev.......eesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGm

VANFGQYRFVYSTVIHYIKN
| .  ||.... ....| |.
vqtseqyelihralclylkr

0036282 (Phosphotyrosine protein) phosphatases II 4-114 2.2e-28 94.5 In-house 64-163 (174) alignment
Range on Protein: 4-114
Range on HMM: 64-163/174.0
KQQRTVYHVQFTDWPDHRVPDDPTsFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQnNKRINIHHALVRLRRQRMLL
   |........ |||| |||... .|||...||. ...          .. ||||||.|||||||.... .||. ..  .. ... . . .||.||.  
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealse.........dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgm

VANFGQYRFVY
| ...||||.|
vqtpsQyrfly

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 6-123 2.7e-28 94.0 In-house 177-285 (319) alignment
Range on Protein: 6-123
Range on HMM: 177-285/319.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
 |.| | |.|.|||| ||.. || |..| ...  |..|         .. |. ||| |||||||  |  | |.  ....  .....   ||| || ..| 
tRevkhfqyteWpdhdvPekatslldllkrirksrekt.........qsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvq

NFGQYRFVYSTVIHYIKN
.  ||.|.| ....... 
rpeqYkfiyealleavea

0041856 (Phosphotyrosine protein) phosphatases II 2-123 6e-28 93.1 In-house 72-173 (182) alignment
Range on Protein: 2-123
Range on HMM: 72-173/182.0
PTKQQRTVYHVQFTDWPDHRVPDdPTSFLEFLDQVESlrqrtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkRINIHHALVRLRRQRM
|.. .|........ |||| ||| . ..|.|...|..              .. ||||||.|||||||.... .||. .     .... .|.  .|..|.
pellerlgiqylylpwpDhgvpd.ldelldfieevle..............eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRp

LLVANFGQYRFVYSTVIHYIKN
  | .  ||.|..  . .....
gmvitpnqyfflqlallellll

0048076 (Phosphotyrosine protein) phosphatases II 4-119 7.3e-28 92.5 In-house 42-141 (145) alignment
Range on Protein: 4-119
Range on HMM: 42-141/145.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIAciqnnKRINIHHALVRLRRQRMLL
   |.........|||| |||..  .||||...|.....           . ||||||.|||||||.... .||.      .......|| ..|.||.  
llerlgiqylylpwpDhgvpdllellleflefieealke...........ggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpga

VANFGQYRFVYSTVIH
| |.||.||.|  . .
vpnpgqlrflyefele

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 3-123 8.1e-28 92.3 In-house 166-278 (281) alignment
Range on Protein: 3-123
Range on HMM: 166-278/281.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTtrssvheskPPVLVHCTAGVGRTGVIILTDLMIACI-QNNKRINIHHALVRLRRQRM
. ..|.| ....| |||| ||.... .||| ..|..|... .           |...|| |||||||. |  | ..  . .........  .  ||..|.
sgetreveqlaytaWPdhGvPattkellefrkevlkltekktk.........aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkern

LLVANFGQYRFVYSTVIHYIKN
|.|    ||.||| .|......
lmvqtvvqyefvykavldaldk

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 4-123 9.4e-28 92.2 In-house 172-282 (318) alignment
Range on Protein: 4-123
Range on HMM: 172-282/318.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|   ..|.|||. ||....|.|... ||..  |.....         |..|||.|||||||| |  | ..  |.... .....   .||.|| |.
eesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgag.........pivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlm

VANFGQYRFVYSTVIHYIKN
|    || |.| ... ... 
vqtedqyefiydvllealas

0051429 (Phosphotyrosine protein) phosphatases II 3-122 3.1e-27 91.3 In-house 116-226 (272) alignment
Range on Protein: 3-122
Range on HMM: 116-226/272.0
TKQQRTVYHVQFTDWPDHRVPDDPtsFLEFLDQVESlrqrtsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRIN--------IHHALV
... |.|.| ..|||||| ||...  .||.|... .               . ||||||.||..|||.... .|... .  .  ..        . .|. 
agearevmhlhytdwpdhgvpqea..llellellld...............ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeave

RLRRQRMLLVANFGQYRFVYSTVIHYIK
.||.||.  | . .||.|.|  ......
elraqrpgavqteeqylflyeallellr

subfamily_PTPN12_pd Subfamily PTPN12 4-123 4.3e-27 89.7 In-house 167-279 (290) alignment
Range on Protein: 4-123
Range on HMM: 167-279/290.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR---INIHHALVRLRRQR
|..|.||  ..|.|||| ||  ..| ||....|..|..          ... |..||| |||||||.||  |..   ....|    ..... ...||.||
kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..........sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqr

MLLVANFGQYRFVYSTVIHYIKN
  ||    ||..|| .|......
aalvqtkeqyelvykavaelvqk

subfamily_PTPN1_pd Subfamily PTPN1 3-122 1.5e-26 87.8 In-house 158-272 (290) alignment
Range on Protein: 3-122
Range on HMM: 158-272/290.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqRTSTtrsSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR---INIHHALVRLRRQ
|.. |...|  .| |||  ||. |..||.|| .|     | |    |. . . |...||.||.||.| ..| | ... |....    ..|.. |. ||..
tqetreilhfhyttwpdfgvpespaaflkflfkv.....resG...slssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrky

RMLLVANFGQYRFVYSTVIHYIK
|. |.    | || | .... .|
rlGliqtadqlrfsylaileGak

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 4-122 5.1e-26 86.6 In-house 182-291 (298) alignment
Range on Protein: 4-122
Range on HMM: 182-291/298.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlRQRTSTTRssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| ...|| |||. ||   || |..|..|.   |. .  .        ||.|.| |||||.|  |  | ..  ..... . ..... .||..|. .
ekerevrqlhftsWpdkgvpenatsvldllrkvra.sqqqagnk........pvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpga

VANFGQYRFVYSTVIHYIK
|    || |.|. |.....
vqteeqYvfiyeavleald

0048179 (Phosphotyrosine protein) phosphatases II 5-115 8.2e-26 85.8 In-house 45-139 (144) alignment
Range on Protein: 5-115
Range on HMM: 45-139/144.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLrqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIaciqnNKRINIHHALVRLRRQRMLLV
  |.........|||| |||... .||||. .|..           .|.. ||||||.|||||||.... .||.      .......|| ..|..|.  |
leregiqylhlpwpDhgvpdllellleflefieea...........leeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgav

ANFGQYRFVYS
 |.||.||.. 
pnpgqlrfLle

0046846 (Phosphotyrosine protein) phosphatases II 10-123 1.1e-25 85.8 In-house 77-175 (176) alignment
Range on Protein: 10-123
Range on HMM: 77-175/176.0
YHVQFTDWPDHRVPDDpTSFLEFLDQVESLRQRTsttrssvheskPPVLVHCTAGVGRTGVIILTDLMIAciqnNKRINIHHALVRLRRQRM-LLVANFG
.......|||| |||. . .||.|..... ...             |||||| ||.||||.... .|..     .| .....|| ..|.||.   | ...
iqylhlpwpDhgvpdl.elllellefirealkeg...........gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpe

QYRFVYSTVIHYIKN
||||.|  . ...|.
Qyrflyefellllkk

subfamily_PTPN23_pd Subfamily PTPN23 3-123 1.4e-25 84.7 In-house 167-282 (288) alignment
Range on Protein: 3-123
Range on HMM: 167-282/288.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLR---QRTSTTrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQN-NKRINIHHALVRLRR
... ..| |.|.| ||.. ||. | ..|.|||.|||     || | |         |..||| ||||||||. |    .. ... |  ..| . . |||.
adavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt.........PlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlre

QRMLLVANFGQYRFVYSTVIHYIKN
||   | .  |..|.|. |......
qRrfmvqekeqlkfsyeavleaarr

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 4-122 2.8e-25 84.1 In-house 174-285 (297) alignment
Range on Protein: 4-122
Range on HMM: 174-285/297.0
KQQRTVYHVQFTDWPDHRVPD-DPTSFLefLDQVESLRQRTSTtrssVHESkpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|..| |   ||..|||. |.  | .| |  |. .. .|.  |.    . |.  |.||||.||||||||..  | ..| ....| ..|   . .||..|. 
karrvvkqyqfveWPdkaverkdsassl..lklisevrkdfsq....naeg..PllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpy

LVANFGQYRFVYSTVIHYIK
||    ||.||| .|. .. 
lvqtkeqykfvyvavleall

subfamily_PTPN13_pd Subfamily PTPN13 3-122 3.3e-25 83.9 In-house 162-270 (273) alignment
Range on Protein: 3-122
Range on HMM: 162-270/273.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... | | |..|..|||| ||  ....|.|. .| .           ..... |..|||.||.||.|..|  | ..  |...| ..... . .||.||  
sgesrevahlnfvkwPdhgvPssaaellqfvaevrr...........lqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqg

LVANFGQYRFVYSTVIHYIK
.|    || ||| .... .|
vvqtkdqyifvykailevlk

0049260 (Phosphotyrosine protein) phosphatases II 9-114 4.1e-25 83.7 In-house 54-143 (152) alignment
Range on Protein: 9-114
Range on HMM: 54-143/152.0
VYHVQFTDWPDHRVPDDPTSFLEFLDQVESLrqrtS----TtrssvheskpPVLVHCTAGVGRTGVIILTDLMIaciqnnKRINIHHALVRLRRQRMLLV
 ...... |||| |||..  .|..|. .| |                    ||||||.|||||||.... .||.      ..... .|. ..|..|.  |
yiqylhlpwpDhgvpdlsqlllflllfiekl....aldkgg..........pvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgav

ANFGQYRFVY
 |.||.||.|
pnpgqlrfly

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 4-122 4.9e-25 83.2 In-house 134-243 (250) alignment
Range on Protein: 4-122
Range on HMM: 134-243/250.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| ...|. |||  ||.  |. ||.|..|.. .|.. ..         ||.|.|.|||||.|  |  | ..  ....| ..... . .||..|.  
aderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagna.........PvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrpha

VANFGQYRFVYSTVIHYIK
|    || |||. ......
vesleqyvfvyeiilkald

subfamily_PTPRK_pd Subfamily PTPRK 3-118 1.2e-24 81.7 In-house 169-274 (314) alignment
Range on Protein: 3-118
Range on HMM: 169-274/314.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
 ...|.| ..||. |||| ||   |..|... .|.. ..           .. ...|||.|| ||||. |  | ..  |.... .....|   || ... 
qeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..........eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvn

LVANFGQYRFVYSTVI
.|    ||.|.|  ..
mveteeqykfiydvil

subfamily_PTPRA_pd Subfamily PTPRA 3-120 1.4e-24 81.6 In-house 187-294 (330) alignment
Range on Protein: 3-120
Range on HMM: 187-294/330.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvheSkpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
 |..| |  . || |||  || .|   |..| .|..|.|...        .  |. |||.|||||||  |  | ... .. .......... ||| ||  
ekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsa........g..pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpq

LVANFGQYRFVYSTVIHY
.|    || |.| .. .|
mvqtdeqyefiykvlley

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 4-119 1.4e-24 82.0 In-house 182-289 (319) alignment
Range on Protein: 4-119
Range on HMM: 182-289/319.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..| .    |  |||. ||| |. .. ....|. |...         . . ...|||.|||||||| |  | ..  ....|...... .  ||.||  |
kdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltske........nhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntl

VANFGQYRFVYSTVIH
| .. || |.||... 
vqdlvqykfiysalle

subfamily_CG7180_pd Subfamily CG7180 5-121 1.9e-24 80.8 In-house 178-290 (296) alignment
Range on Protein: 5-121
Range on HMM: 178-290/296.0
QQRTVYHVQFTDWPD-HRVPDDPTSFLEFLDQVESLRQRTsttrsSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
..|.| ..|.| |.  ..||   ....|.. .|...|...       .. . ||.|... |..|.|| .  |  .  ......... .|. .|||.|  |
etRivklfqlteWeledkvPlstnalielrrrvrlwrekv.....dedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqL

VANFGQYRFVYSTVIHYI
| |  .|...| .. ...
venveeYkyiYdvlleav

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 4-119 2.7e-24 81.1 In-house 146-253 (284) alignment
Range on Protein: 4-119
Range on HMM: 146-253/284.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..|..    |  |||. ||| |. .. ....|. |...         . . ...|||.|||||||| |  | ..  ....|...... .  ||.||  |
kdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltske........nhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntl

VANFGQYRFVYSTVIH
| .. || |.||... 
vqdlvqykfiysalle

subfamily_PTPRG_pd Subfamily PTPRG 4-122 3e-24 80.2 In-house 180-288 (563) alignment
Range on Protein: 4-122
Range on HMM: 180-288/563.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
.....|.. ..|.|||| ||. ..  | |  .             . ..   |..||| |||||||. |  | ..  ||... .|... | ..| ||  |
dteklvrqyhytkWPdhgvPehslpvLifvkks..........saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnfl

VANFGQYRFVYSTVIHYIK
|..  || |.. ...  |.
vqteEqYiflhdalleaia

0044763 (Phosphotyrosine protein) phosphatases II 10-123 3.5e-24 80.8 In-house 76-173 (178) alignment
Range on Protein: 10-123
Range on HMM: 76-173/178.0
YHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkRINIHHALVRLRRQRMlLVANFGQ
...... .||| ||| .  ||||.. .|...          .|.. ||||||.|||||.|.... .||. .     ......|. ..|..|.  | |.||
iqylhipipDhgvpdllehflefvefieeal..........dekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgq

YRFVYSTVIHYIKN
.|..|    .. |.
lrqLyefelrllke

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 5-122 1e-23 78.2 In-house 170-277 (515) alignment
Range on Protein: 5-122
Range on HMM: 170-277/515.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtSTTRSSvHeskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
. |||   .||.|||. || . .|.| .. .| .     .. . . |    |...||.||||||||.|  | ..| ... . ... . .  .|..|. ||
dsrtvtqfhfteWPdkGvpkhtssllklikevka.....dhgqyt.h....pliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylv

ANFGQYRFVYSTVIHYIK
    || |.| .|  ...
qtqeqyafiygavledll

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 4-122 1.5e-23 78.2 In-house 170-278 (315) alignment
Range on Protein: 4-122
Range on HMM: 170-278/315.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrsSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|||   |||.|||. |. . .|.|... .| .          . .. . ..||||.||||||||.|  | ..| |.... ... . .  ||..|. |
eesrtvtqfqftewPdkGvdkqtssllklikevka..........dngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpyl

VANFGQYRFVYSTVIHYIK
|    .| |.| .|  ...
vqteeeyafiydavledll

0051082 (Phosphotyrosine protein) phosphatases II 5-115 2.2e-22 74.7 In-house 56-147 (151) alignment
Range on Protein: 5-115
Range on HMM: 56-147/151.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkrINIHHALVRLRRQRMLLV
....|.|....||||. .|. . ..||||.....              .. ||||||.||.||||.... .||.        ...  ||  .|..|. .|
lgievlhipildwpdpglplsfdavleflellld.............kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvv

ANFGQYRFVYS
  . |..|.. 
qpnqqflfqlf

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 3-122 4.2e-21 69.9 In-house 170-280 (439) alignment
Range on Protein: 3-122
Range on HMM: 170-280/439.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|...||| ..... |||. || . .  |.||  ..|  ..         |   ||.|||.||||||| ||  |. .  .. .....|.  .  ||.||  
tekertvlqfhyiawpdknvpaqashvldflrainsandk.........eeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkq

LVANFGQYRFVYSTVIHYIK
.| .. || |.| .|.  |.
mvqalcqyvfiynavlediv

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 6-118 6.9e-21 69.5 In-house 174-276 (315) alignment
Range on Protein: 6-118
Range on HMM: 174-276/315.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvheskPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
 |.|. ...| |||  ||   ......  .|   .. .            ...||| |||||||  |  | ..  .. .. |...... ..|..|. .|.
irevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv..........gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvq

NFGQYRFVYSTVI
   ||.|.|....
vaeqyqfiydall

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 6-121 3.8e-20 67.3 In-house 177-288 (325) alignment
Range on Protein: 6-121
Range on HMM: 177-288/325.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTST-TRSSVheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
 |.|   |.  |.|  |.  |.... .|. |. . .|  . |..|      |.||||.|||||||| |    ..| . .. |..|   . .||..|  .|
trsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkast.....pilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmv

ANFGQYRFVYSTVIHYI
    || ..| ... ..
etvdqyiliyealveay

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 4-122 7.6e-20 65.9 In-house 161-296 (297) alignment
Range on Protein: 4-122
Range on HMM: 161-296/297.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEF--------------LDQVE---SLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR
...| | ||||  |||| || |      |              |  ||   ..      .  . .  . ..||||.|||||.||..|.| ..| ..... 
sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkri

INIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
 ..   |  || ||  ||  . |. ..|. |.. .|
pdvaailsilreqrarlvqtleqfellydavlkklk

0049772 (Phosphotyrosine protein) phosphatases II 6-122 8.5e-20 67.1 In-house 177-281 (314) alignment
Range on Protein: 6-122
Range on HMM: 177-281/314.0
QRTVYHVQFTDWPDHRVPdDPTSFLEFLDQVESLrqRtsttrssvheSKPPVLVHCTAGVGRTGV-IILTDLMIACiqnnkRINIHHALVRLRRQRM---
.|.....  ...||. .| ..  |.|||. .|..  .           . ||||||.||.||||. ...  ||...     ..... || ..|..|.   
erlgikylripvpDgsap.lledfdeflefieea..d..........kggpvlvHCkaGkgRtgtfvvaaylmkll.....gvsleealedvrlkRpinp

--LLVANFGQYRFVYSTVIHYIK
   .. .. || |..  . .|.|
npgfieqleqyefilealleylk

subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 3-123 1.8e-19 64.6 In-house 172-278 (312) alignment
Range on Protein: 3-123
Range on HMM: 172-278/312.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLdqveslrqrtsttrSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
| |.  . | |.. |||| .||   . | .|              |.|.  | ||. ||.||||||| ..| . |||...  .. |.....| ||..|  
tgqesklnhyqwaswpdhgmpdscdtalrll..............savkkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrar

LVANFGQYRFVYSTVIHYIKN
 |  | || ..  .|.... .
svrvfpqyvyalrcvleflys

subfamily_PTPRN_pd Subfamily PTPRN 3-121 3.5e-19 63.6 In-house 183-292 (297) alignment
Range on Protein: 3-121
Range on HMM: 183-292/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVEslrqRTSTTRSSvheskpPVLVHCTAGVGRTGVIILTDLMIACIQ-NNKRINIHHALVRLRRQRM
|.. |||    |  ||.. ||  . |.|||  .|.    ..   ||.      |..|||..|.||||| || ||... ..   |.|.|  .|  || || 
tsetrtvtqfhflswpeegvPasaksllefrrkvn....ksyrGrsc......pivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrp

LLVANFGQYRFVYSTVIHYI
 ||.   |..|....|.. .
glvktkdqfefaltavaeev

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 5-119 8.8e-19 62.2 In-house 130-234 (392) alignment
Range on Protein: 5-119
Range on HMM: 130-234/392.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrQRTSTTrssvHeskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..|||   .||.|||. ||   .|.|.|. .|..  .  . |    |    |...||.||||||||.|  | ..|  .. . ...   .. .||.|  .|
dartvaqfhftewPdkdvpkhtssllkfikevka..dfGqyt....h....pliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymv

ANFGQYRFVYSTVIH
    || |.| .|. 
qtkeqyafiygavle

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 8-122 1.7e-18 61.5 In-house 216-345 (350) alignment
Range on Protein: 8-122
Range on HMM: 216-345/350.0
TVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIA------CIQNNK---------RINIHHA
 ||..|.  |.|  .  .| |.|. |.  . | .   .   .  .  .|.|||| |||||||...  | ..        ....          |  |.  
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii

LVRLRRQRMLLVANFGQYRFVYSTVIHYIK
. .||.||. .| |  |. |.| .. .| .
vnelrkqrismvqnldqfifiYeallfyfa

subfamily_CG42327_pd Subfamily CG42327 45-122 3.4e-18 60.4 In-house 238-316 (319) alignment
Range on Protein: 45-122
Range on HMM: 238-316/319.0
TTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNN-KRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
..||. .||. |. |||. ||||||..| .|. |  .... . ..| . .  .||.|   | .  || |.| ..  | |
ssrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyak

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 4-123 2.3e-17 57.8 In-house 175-285 (290) alignment
Range on Protein: 4-123
Range on HMM: 175-285/290.0
KQQRTVYHVQFTDWPDHR-VPDDPTSFLEFLDQVESLRQRtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
.....| . |.| |...  |..  |. | .  ...  |.|           . ...||| ..|||..| . ..  |   . .  |.. . | ..| |.. 
gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkr..........gntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpg

LVANFGQYRFVYSTVIHYIKN
.|    ||..... |..|...
svqtvqqyqgifqivltylds

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 3-123 3.2e-17 57.3 In-house 164-279 (287) alignment
Range on Protein: 3-123
Range on HMM: 164-279/287.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFldqVESLRQRTSTTRSSvHESKpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|.. | |  ... .|||. ..    ... |   | . .|.   .|..  |   |..||. .|.||.|... |  ..   ..  |...  ...||| .|  
trearvvkqldllswPdkvlaPtavglirf...vldvkqhielarda.sevG.PlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraa

LVANFGQYRFVYSTVIHYIKN
||    |.|..| ... | | 
lvqavvqlrllyealvtyykt

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 4-118 3.2e-17 57.5 In-house 130-236 (237) alignment
Range on Protein: 4-118
Range on HMM: 130-236/237.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtSTTRSSVHESkPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|. | ..  ||| |||. ||.  ...| |  ..             | ||  | ..||.|||||||.... | |.   ...| ..|.  .  .  .|  .
kevrlihqyqftswpdrgvpqqtaallrfrkni.......inrsphvses.gpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyi

VANFGQYRFVYSTVI
.    || |.. |..
iqtkdqyvfihqtil

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 4-123 6.8e-17 56.4 In-house 170-280 (287) alignment
Range on Protein: 4-123
Range on HMM: 170-280/287.0
KQQRTVYHVQFTDWPDHR-VPDDPTSFLEFLDQVESLRQRTSTtrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
.....|   |.|.|.... |..  |..| . ... . |.|. |          ...|||...|||... .  .  |   ...  |..   | . | |.. 
gdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgnt..........sivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpg

LVANFGQYRFVYSTVIHYIKN
 |    ||.|..  |..|.. 
svqtveqykfindivleylds

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 7-122 8.3e-17 55.5 In-house 218-345 (349) alignment
Range on Protein: 7-122
Range on HMM: 218-345/349.0
RTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIA------------CIQNNKRINIHHALV
  .. .|. .|.|  .  .| |.|. |.  . |     .      .  ...||||.|| |||||..  ||...             .|. ..  |. .. 
yellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivn

RLRRQRMLLVANFGQYRFVYSTVIHYIK
 ||.||. .|.|. |. ..| ....|..
elrkqrismvqnlaqfiaiyealLkyfa

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 4-121 2.4e-16 54.3 In-house 185-289 (305) alignment
Range on Protein: 4-121
Range on HMM: 185-289/305.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLdqveslrqrtsttrSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVR-LRRQRML
.|. .| |.|.|.|||  ||    . ||.|              |..  || |..|||.||.|||| |.  . ..  | .||.      ||. || ||  
dqkmsvrhlqwtewpdrgvppckltslell..............sairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqraf

LVANFGQYRFVYSTVIHYI
 . |  || |..  .. |.
siqndvqylfihrvmlnyf

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 3-126 2.8e-16 54.1 In-house 182-292 (305) alignment
Range on Protein: 3-126
Range on HMM: 182-292/305.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQveslrqrtstTRSsvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRIN-IHHALVRLRRQRM
 ...| | |  . ||||  ||   .. ||.| .          .|.    || |. |||.||.|||| ... . ..  . . . |.  .. |...| || 
gekarkvthyhwidwpdrgvpaadlailellek..........arp....skgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrn

LLVANFGQYRFVYSTVIHYIKNSRL
  .    || ||.  .. |... .|
nsiqtdaqylfvhqvilnyfrkkkl

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 5-121 3e-16 54.3 In-house 169-271 (288) alignment
Range on Protein: 5-121
Range on HMM: 169-271/288.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttrS---SvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRM
..  | .. . .|.|. ||..  |.| .|. .                      |..||. ||||||| .||. ...  .. .  . |.. | .|| .|.
ekvivkilhlleWdddgvPenylsplrllevl...........kslqk......PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerf

LLVANFGQYRFVYSTVIHYI
  .    || .|.  | ...
kaiqtemqylyvhrcvleel

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 5-118 5.1e-16 53.6 In-house 134-237 (239) alignment
Range on Protein: 5-118
Range on HMM: 134-237/239.0
QQRTVYHVQFTDWPDHRVPDDPTSFLefldqveSLRQRtsTTRSSVHESKPPVlVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| ||. .|| |||. ||.  |. |        ||..   |. |.  ..| | .||.||||||| ... | |.   ...| ..|   .  .| .|  .|
eeryvyqyhftvwpdkgvpqyatavl.......glrrk..itkdslpgarpwv.ihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmv

ANFGQYRFVYSTVI
    || |.. .|.
qtseqyvfihlavl

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 5-118 5.9e-16 53.4 In-house 135-238 (239) alignment
Range on Protein: 5-118
Range on HMM: 135-238/239.0
QQRTVYHVQFTDWPDHRVPDDPTSFLefldqveSLRQRtsTTRSSVHESKPPVlVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| ||. .|| |||. ||.  |. |        ||..   |. |.  ..| | .||.||||||| ... | |.   ...| ..|   .  .| .|  .|
eeryvyqyhftvwpdkgvpqyatavl.......glrrk..itkdslpgarpwv.ihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmv

ANFGQYRFVYSTVI
    || |.. .|.
qtseqyvfihlavl

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 4-122 4.8e-15 50.0 In-house 185-294 (301) alignment
Range on Protein: 4-122
Range on HMM: 185-294/301.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|. ..|  .| ||||.. |  .|   |. .|.|   .|.          .. ||.||| ..|.|.|| .  .. .   . .  ...     ..||...  
ksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqki.........gggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpga

VANFGQYRFVYSTVIHYIK
|    || ..|  .  |..
VtTLeqytsiydvidmylq

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 6-120 1.9e-14 48.1 In-house 180-281 (301) alignment
Range on Protein: 6-120
Range on HMM: 180-281/301.0
QRTVYHVQFTDWPDHRVPDdptSFLEFLDQVESlrqrtsttrssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
 ||| | |...|.|. ||    |  |  | .|            | .|. |..|||.||.||.   | |. .   ......|.. .|| .|| .|   | 
trtvthyqysewtdrgvPk...shaelfdlmel...........vkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvq

NFGQ-YRFVYSTVIHY
.  | |     ||   
tnsqlywmtlGtvyrl

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 4-121 3.9e-14 47.4 In-house 173-277 (307) alignment
Range on Protein: 4-121
Range on HMM: 173-277/307.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLdqveslrqrtsttrSSVHESKPPVLVHCTAGVGRTGVIILTDL-MIACIQNNKRINIHHALVRLRRQRML
.. ||. |.|...|||. ||.   . ...|              ..|.  . ||.|||.|||||.| |.   | .   |.     .... .  || ||  
qksrtiqhlqwenwpdrgvpqinltainll..............eavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhy

LVANFGQYRFVYSTVIHYI
 . .  || ...  ...| 
aiqteaqylylhrvlleyf

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 5-119 7.6e-14 45.9 In-house 87-192 (440) alignment
Range on Protein: 5-119
Range on HMM: 87-192/440.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
. ||. . ..  |||. ||      |.....|.  ....         .. |.||||.||.|||||||  | ..   . . .|.|   .  .| .|  .|
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqeka.........gngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmv

ANFGQYRFVYSTVIH
    || ||. .|..
qtpeqyafvheavle

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 9-123 1.1e-13 45.2 In-house 185-287 (302) alignment
Range on Protein: 9-123
Range on HMM: 185-287/302.0
VYHVqfTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
||..  | |....||.  ..  .   .|            .  ... ....  . |.|| |...   . . ..|..|  ||.  .  .| ||   | .. 
vyvl..tnWkqkkvpvkyaeliktaakv..........fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslk

QYRFVYSTVIHYIKN
|| ..| ... |||.
Qyvslyialllyikk

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 48-121 1.8e-13 45.1 In-house 186-259 (267) alignment
Range on Protein: 48-121
Range on HMM: 186-259/267.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYI
  . .  .|..|.|..||||.|  .  | ..  ....   .|.. | ..| ||. ||    .| ... .. .| 
nqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 9-118 2.3e-13 44.7 In-house 164-263 (283) alignment
Range on Protein: 9-118
Range on HMM: 164-263/283.0
VYHVQFTDWpdhrvpddpTSFLEfLDQVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
. | |. ||         ... |    ..|| .         .. | |..|||..|.|||.| |     .  .. .  ...   .  .| ||| .| . .
lahyqvidW.........leyge.qaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtld

QYRFVYSTVI
||..|.  |.
qyklvhelvl

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 9-121 5e-12 40.4 In-house 169-270 (285) alignment
Range on Protein: 9-121
Range on HMM: 169-270/285.0
VYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
. |||   |||.  |.|   ..|.   |.            |   . |. |||.||||||  ..  |     | .|  |..   .  .|  |.  | .. 
mnhvqvpwwpdqlapedarpmielykwvkk...........vnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshm

QYRFVYSTVIHYI
|. |.|  .. |.
qflflyvvlmeyf

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 6-123 7.7e-12 39.4 In-house 182-285 (290) alignment
Range on Protein: 6-123
Range on HMM: 182-285/290.0
QRTVYHVQFTDWPDHRVPDdptSFLEFLDQVESLRQRTSttrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
.  ..|..   |||. |.    | | .|  . .||. .            || |||.||.|||| ..  .  . .. . | ...      ||. |.  | 
ehklkhlkikswpdksval...stlallrtlrilrkasG...........pvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvq

NFGQYRFVYSTVIHYIKN
   ||  .   .... |.
vdiqylalveilldlGkd

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 4-106 9.4e-12 39.0 In-house 185-273 (302) alignment
Range on Protein: 4-106
Range on HMM: 185-273/302.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvheskppVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|...||  ..|. ||||  |... . |. |   || ..               |||||.||||||| ..     |   ...|  .. . .. .|. |   
kvkktvdilafsawpdhGapkeaytaldilkfcesykkn..............vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGa

VAN
| .
vqd

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 4-121 1.4e-11 39.1 In-house 155-259 (290) alignment
Range on Protein: 4-121
Range on HMM: 155-259/290.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVEslRqrtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQ-NNKRINIHHALVRLRRQRML
... || | .. .| .  |..|. ..|. ...|.               || ||.|||. |. |  ..   .|    |   .. .... .|  ||.|| |
eeeftvtHsllkgWnklnvqedtktllsliqkvk..a............sktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqral

LVANFGQYRFVYSTVIHYI
.. .  .. ||   .. ..
aitsalelafvdagivlla

0038934 (Phosphotyrosine protein) phosphatases II 15-114 3.4e-11 38.6 In-house 85-170 (194) alignment
Range on Protein: 15-114
Range on HMM: 85-170/194.0
TDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkRINIHHALVRLRRQRMLLVANFGQYRFVY
  .||. .. .    |.||| |.   .. .         .  |.|||.||.||||...   |.  .     ... . |. ..|. |   . | .... ..
lpfpddgtvPsleillrfldlvdeflnedp.........ggvvaVHCkaGlgRtGtlvaaYLiyrl.....gmsaeeAialfrekRpgaipnqdyleall





subfamily_ptpA1_pd Subfamily ptpA1 6-79 4.3e-11 37.2 In-house 185-254 (418) alignment
Range on Protein: 6-79
Range on HMM: 185-254/418.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlRQrtSTTRSSVhESKPPVLVHCTAGVGRTGVIILTDLMIA
 | . . |.  |||| .||    | ..|  .   ||       |  . . |..|||.||||||| .  . .|. 
trditqyqyegwpdhnipdhtqpfrqllhsitn.rq..nqiipss.drnvpiivhcsagvgrtgtfctavimmk

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 6-115 2.8e-10 34.7 In-house 93-197 (198) alignment
Range on Protein: 6-115
Range on HMM: 93-197/198.0
QRTVYHVQFTDWPDHRVPDDpTSFLEFLdqvESLRQrtsTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR--INIHHALVRLRRQRMLL
 | . | ||| | ..  |.  . |. |.    . |.    ..    |   ||.|||. | | |||..  |. .   .. |   ...     |||. |  .
treishyqftswkekttpnv.alfvgfv...vasre...vskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgi

VANFGQYRFVYS
.. . .| |.| 
isslqhynfiyq

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 6-115 2.9e-10 34.7 In-house 94-198 (199) alignment
Range on Protein: 6-115
Range on HMM: 94-198/199.0
QRTVYHVQFTDWPDHRVPDDpTSFLEFLdqvESLRQrtsTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR--INIHHALVRLRRQRMLL
 | . | ||| | ..  |.  . |. |.    . |.    ..    |   ||.|||. | | |||..  |. .   .. |   ...     |||. |  .
treishyqftswkekttpnv.alfvgfv...vasre...vskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgi

VANFGQYRFVYS
.. . .| |.| 
isslqhynfiyq

subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 59-122 1.5e-09 32.0 In-house 2-65 (69) alignment
Range on Protein: 59-122
Range on HMM: 2-65/69.0
VHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
|||..| ||||  |   . .| |. .| ..|   .  .|. | ..| |  .| |.. ...  .|
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealk

subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 13-122 1.8e-09 31.6 In-house 233-339 (347) alignment
Range on Protein: 13-122
Range on HMM: 233-339/347.0
QFTDWPDHRVPDDPTSFLEFldqVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRF
. | || .. |||    | .   | .  . .||.  .  | ..||.| |  |. |.  ..|| ..|  . . |  .    . ..| ||  . .    | .
ncttwpwkkypddekkvlal...vrapvkesstslianleklapvvvmcdlgldrsatvvltsiiieqvldgktpdcddlfkkmrdqragvftmsifyty

VYSTVIHYIK
   . . |.|
airaalfylk

subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 58-122 2.1e-09 31.6 In-house 2-66 (69) alignment
Range on Protein: 58-122
Range on HMM: 2-66/69.0
LVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
.|||..| |||| .|   . .| |. .| ..|   .  .|. | ..| |  .| |.. ...  .|
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealk

subfamily_eak_pd Subfamily eak 55-123 4e-09 30.3 In-house 234-307 (332) alignment
Range on Protein: 55-123
Range on HMM: 234-307/332.0
PP---VLVHCTAGVGRTGVIILTDLMIACIQNNKR--INIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIKN
||    .. .. |  |.|| .. ||.|  |.|.|.    . . ... . .|.  |    |. |.|  |..|...
ppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllr

PTPc_motif_SM00404 6-110 1e-08 30.1 In-house 46-133 (140) alignment
Range on Protein: 6-110
Range on HMM: 46-133/140.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMiacIQNNKRINIHHALVRLRRQRMLLVA
.... ...  |     . ..  . |.|....              ....  |||||.||| |.. .|.  ||    ...  ..    .|. ||...   .
gfqilqiplddnekdklskyldkvldfiena..............ekkggkvlVHCqaGvSRSatliiaYlm...ryrqlslaeayefvkerRpiispnl

NFGQY
|| . 
nfvrq

subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 8-122 1.1e-08 29.0 In-house 171-280 (303) alignment
Range on Protein: 8-122
Range on HMM: 171-280/303.0
TVYHV-QFTDWPDHRVPDD-PTSFLEFLDQVESLRQRTSttrssvhESKPPVLVhCTAGVGRTGVIILTDLMIACIQN-NKRINIHHALVRLRRQRMLLV
.  || .. .||   .| |    |.  . |..|. .. |       .|.|.| .   .|.||.| . | .     ... .  ... . |  .|  |.  |
sflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkys.......dstptvym.slsgcgragtfalfetahlslhseqasldlvkclenvrngrlhav

ANFGQYRFVYSTVIHYIK
 |. |. .||. .  .. 
qnlsqfsvvytllaehvl

DSPc Dual specificity phosphatase, catalytic domain 48-111 1.1e-08 30.0 Pfam-A 67-125 (133) alignment
Range on Protein: 48-111
Range on HMM: 67-125/133.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQYR
.......  |||||.||. |.. .|.  ||     . |.... .|.  ....|  .. |.|. |
ekaeqkgkkvlVHCqaGisRSatliiaYlm.....ktknlslneAyefvkerrskispnagflr

DSPc Dual specificity phosphatase, catalytic domain 48-111 1.1e-08 30.0 In-house 67-125 (133) alignment
Range on Protein: 48-111
Range on HMM: 67-125/133.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQYR
.......  |||||.||. |.. .|.  ||     . |.... .|.  ....|  .. |.|. |
ekaeqkgkkvlVHCqaGisRSatliiaYlm.....ktknlslneAyefvkerrskispnagflr

PTEN_1 53-112 1.2e-08 30.0 In-house 129-184 (196) alignment
Range on Protein: 53-112
Range on HMM: 129-184/196.0
SKPPVLVHCTAGVGRTGVIILTDLMIACIqnnkrINIHHALVRLRRQRM-LLVANFGQYRF
..  |||||.||.||.|...   || .        . . || ..|..|.   . .. | |.
ngnvVlVHCkaGlgRsGtvvaayLmykgk.....ltadeAlelvrekRppgapnspsqerl

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 9-120 1.4e-08 28.6 In-house 192-289 (310) alignment
Range on Protein: 9-120
Range on HMM: 192-289/310.0
VYHVQFTDWPDHRVPDDptsflefldQVESLRQRTSTtrsSVheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
|  ... .|||  |||.         .. .. ||  .    |   . |..|||.||..|..|..  .| |  ... .......    |...|.  . .  
vslikwpnwpdrgvpde.........kchtvpqrlla...qv..rhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtel

QYRFVYSTVIHY
|| ..    | .
qyliidrvriif

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 6-118 2.7e-08 27.8 In-house 166-266 (281) alignment
Range on Protein: 6-118
Range on HMM: 166-266/281.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslRQRtsttrssvheSKPPVlVHCTAGVGRTGVIILTDLMIACIQNNKRI-NIHHALVRLRR-QRMLL
 | . |  . .||| .||.    .|. | ..   | |          | ||| .||.|||||.| ..  .. .  |..   . .|.. . .||   |   
trlithwlwkewpdwqvpessevmlkilrki...rar..........stppv.ihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraas

VANFGQYRFVYSTVI
|  . || ...  ..
vqtlqqymliwkvll

subfamily_PTEN_pd Subfamily PTEN 54-114 6.6e-08 27.7 In-house 114-173 (184) alignment
Range on Protein: 54-114
Range on HMM: 114-173/184.0
KPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRiNIHHALVRLRRQRMLLVANFGQYRFVY
|  | ||| || |||||.| . |. ... .... .. .   . | .    |    | |.|.
knvvvvHCkaGkGRtGvlivayllkslllekae.ealelfaeaRtknkkgvtiPsqrRYve

subfamily_PTPDC1_pd Subfamily PTPDC1 48-116 7.7e-08 27.0 In-house 110-171 (182) alignment
Range on Protein: 48-116
Range on HMM: 110-171/182.0
SSVHESkpPVLVHCTAGVGRTGVIILTDLMIAciqnnKRINIHHALVRLRRQRMLLVANFGQYRFVYST
....|    | ||| || |||||.| . |. |     ||.. ..|.  .| .|   .   .| ..|   
falqeg..kvavhChaGlGrtGvliacylvya.....krltaekaiklvrskrpksiqtreqvelvkef

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 4-119 2.2e-07 25.2 In-house 113-219 (255) alignment
Range on Protein: 4-119
Range on HMM: 113-219/255.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQveslrqrtsttrssVHESKpPVLVHCTAGVGRTGVIILTDL----MIACIQNNKRINIHH--ALVRLR
|. .|| | ... |...  |...   |. |                |..|| .|.|||..|.||.   .|..|    ||  ... . ... .   |  ||
kkthtvkhysykGWieknaPelareilnilkv..............vrdsk.svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelr

RQRMLLVANFGQYRFVYSTVIH
 .|   . .  |  |   .|. 
skrkraihtPlqlafsilmvld

subfamily_DSP19_pd Subfamily DSP19 51-109 6.4e-07 23.8 In-house 86-139 (152) alignment
Range on Protein: 51-109
Range on HMM: 86-139/152.0
HESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQ
....  ||||| ||| |.  .... ||     .........||  .| .|  .  | | 
rskdgavlvHCnAGvSRsasvviaylm.....kkeelsleealelvrearpcikPneGF

subfamily_egg_pd Subfamily egg 53-122 8e-07 23.0 In-house 200-271 (307) alignment
Range on Protein: 53-122
Range on HMM: 200-271/307.0
SKPPVLVHCTAGVGRTGVIILTDLMIACIQ--NNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
   ||.|..  || ......  .. .  .      .  . .| | ||..| | |    .| |||  |. ...
lskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffr

Y_phosphatase3 Tyrosine phosphatase family 40-79 2.1e-06 22.8 Pfam-A 110-149 (164) alignment
Range on Protein: 40-79
Range on HMM: 110-149/164.0
RQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIA
... ..  . . |.. |||.|||||  ||||..   | ..
kkayrkvlealaeeegpvlfHCtaGKDRTGvvaalllsll

subfamily_DSP3_pd Subfamily DSP3 48-103 2.9e-06 21.0 In-house 91-141 (162) alignment
Range on Protein: 48-103
Range on HMM: 91-141/162.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMIAciqnnKRINIHHALVRLRRQRMLL
.......  |||||..|| |  ...|  |||      .......|. . |..|..|
ealsqkegkvlvhcvvGvsRsatlvlayLmir.....rkmtlveairtvrkkReil

subfamily_DSP1_pd Subfamily DSP1 49-108 5.2e-06 20.6 In-house 90-144 (163) alignment
Range on Protein: 49-108
Range on HMM: 90-144/163.0
SVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFG
.|....  ||.|| ||. |   ..|  ||     ..||.... |    ...| .   |.|
evkkknGkvlihCqaGisRsstlclaylm.....ktkrvsleeafdfvkqrRsiisPnag

subfamily_DSP14_pd Subfamily DSP14 47-111 8.3e-06 19.8 In-house 76-135 (157) alignment
Range on Protein: 47-111
Range on HMM: 76-135/157.0
RSSVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQYR
  .|....  .||||.||| |   . |  ||     . .......|   .. .| ..  | | ..
ieevkkkggktlvhCvaGvSRSAslclaylm.....kyeklsLreayklvksaRpiirPNvGFwk

subfamily_DSP12_pd Subfamily DSP12 30-104 9.6e-06 20.1 In-house 65-127 (155) alignment
Range on Protein: 30-104
Range on HMM: 65-127/155.0
LEFLDQVESLRQRTS-TtrssvhesKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLV
|..||.. .  . .  .        .  |||||.||| |   |..  ||      ........||  .....    
LshldeavdFieealee........egavlvHCqagvSRSvtiviAYlm.....kkeklslekAlklvkekkpeie