Gene PPS1 in Saccharomyces cerevisiae

Synonym: YBR276C, PPS1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP006_AA protein Get Run
ScerP006_AA_585-778 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PTPc_motif_SM00404 586-780 4.2e-61 199.9 In-house 2-140 (140) alignment 
Range on Protein: 586-780
Range on HMM: 2-140/140.0
PSRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVVSWTlnkdkiahpvrphraitmtntnevagnttcnksrnradtvvsdkqengsnvviSENSGFQ
|||||.||||||...||||||||.|||||...|.|.||.|                                                     .||||||
psrilphlylgskskaqnpallkklgithvinvteevslt.....................................................kensgfq

ICQIEnLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWWKK
|.||. ||||.||.|....|||||||.|.|..||||||||..|||||||..||..||| |..||.|| ||..||  .||.|||.||..|....||
ilqip.lddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerR..piispnlnfvrqLieyekk
0044763 (Phosphotyrosine protein) phosphatases II 582-784 1.7e-32 107.9 In-house 19-173 (178) alignment 
Range on Protein: 582-784
Range on HMM: 19-173/178.0
KGPLPSRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVVSWTLNKDKIAHPVRPHraitmtntnevagnttcnksrnradtvvsdkqengsnvvisen
 .. .|.|| .|||||| .|....||| |||||||.. | . .  .|.   .| . .                                           
dyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeag...........................................

sgFQICQIeNLDDNGKDPLFHQIDKVLDFISNSE-ATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnViIQPNLFFVYELFKWWKK
  .| ..| ...|.|  .|. .......|| .     ||.|||||. ||.||.|...|  |..|...| .|. .|| ||    |.||  ... | .....
..iqylhi.pipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerR..p.ivpnpgqlrqLyefelr

HYNR
... 
llke
0041856 (Phosphotyrosine protein) phosphatases II 583-784 7.8e-32 105.7 In-house 16-175 (182) alignment 
Range on Protein: 583-784
Range on HMM: 16-175/182.0
GPLPSRILRHLYLGSLDH--------------AQNPALLKSLGITHIVSVGEVVSWTlnkdkiahpvrphraitmtntnevagnttcnksrnradT-Vvs
.. ...|. .|||||| .              |..  .||.||||.||.. |.  |                                       . .  
srdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywp......................................ell..

dkqengsnvvisENSGFQICQIENLDDNGKDplfhqIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPN
            |. |.|....   |..  |     .|..||||   .. ||.|||||. ||.|..|...|  |..|...| .|. .|| || ...|.||
............erlgiqylylpwpDhgvpd.....ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpn

LFFVYELFKWWKKHYNR
 .|.. |. ....... 
qyfflqlallellllkk
0045098 (Phosphotyrosine protein) phosphatases II 578-784 1.5e-28 95.4 In-house 14-274 (278) alignment 
Range on Protein: 578-784
Range on HMM: 14-274/278.0
FVNLKGPLPSRILRHLYLGSLD-----------------------------------------HAQNPALLKSLGITHIVSVGEVVSWTLN---------
...|  . ||.|. .||||.||                                         .|..  .|..||||.||.. |.| .. .         
efllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeg

--------------KDKIahPVRPHRAITMTNTN----EvagnttcnksrnradtvvsdkqengsnvviSENSGFQICQIENLDDNGKDPLF--HQIDKV
               . .  .   .| ...||..    .                               |. |... .. . .|.|  .|    .....
gsltygdftvtllseevl..ddytlrtllvtnltvered..............................lesrgvthlhylpwpdhgvpslpilksflel

LDFISNSEA--------------TGGKVLVHCMVGVSRSATVCIAECMRYL---QCDLASAYLFVRVRRlNVIIQPNLFFVYELFKWWKKHYNR
|.|| .  .               ||.|||||. ||.|..|...| .|..|   ..|| .|. ..| .| . ....|| . . |...  ....|
lefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqR.pglavqnleqyrflyefllelllr
0048076 (Phosphotyrosine protein) phosphatases II 585-778 4.6e-27 89.8 In-house 3-139 (145) alignment 
Range on Protein: 585-778
Range on HMM: 3-139/145.0
LPSRILRHLYLGSLDHAQNPALLKSLGITHIVSVgevvswtlnkdkiahpvrphraitmtntnevagnttcnksrnradtvvsdkqenG------Snvvi
 ||.|| .|||||| .|.. .|||.||||.....                                                             .    
wpseilpglylgslptaldlellkdlgittvlnl......................................................tselelle....

seNSGFQICQIeNLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPNlfFVYELFKWW
  . |.|.... ...|.|  .|. .....|.|| .  . ||.|||||. ||.|..|...| .|..|...| .|. .|| .| .... |.  ... |....
..rlgiqylyl.pwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpgavpnpg..qlrflyefe
0048179 (Phosphotyrosine protein) phosphatases II 584-775 2.8e-26 87.4 In-house 2-138 (144) alignment 
Range on Protein: 584-775
Range on HMM: 2-138/144.0
PLPSRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVVSWTLNKDKiahpvrphraitmtntnevagnttcnksrnradtvvsdkqengsnvvisensG
. ||.|| .|||||| .|.. .|||.||||..... |   ..  ..                                                     |
snpseilpglylgslptaldlellkklgittvinlteeyepeflere....................................................g

FQICQIeNLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPNlfFVYELF
.|.... ...|.|  .|.......|.|| .  . ||.|||||. ||.|..|...|  |..|...| .|. .|| || .... |.  ... | 
iqylhl.pwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrpgavpnpg..qlrfLl
0049772 (Phosphotyrosine protein) phosphatases II 573-782 3.7e-24 81.5 In-house 92-274 (314) alignment 
Range on Protein: 573-782
Range on HMM: 92-274/314.0
PLESNFVNL--------------------------------------------KGPLPSRILRHlylgSLDHAQNPALLKslgithivsvgevvswtlnk
||| ..|..                                            | ||..   ..    .. .|....|||                    
pleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng....neptaadlellk....................

dkiahpvrphraitmtntnevagntT-------CnksrnradtvvsdkqengsnvvisENSGFQICQIeNLDDnGKDPLFHQIDKVLDFISNSeATGGKV
                         .       .                        |. |.. ..| ...| |  ||. ..|..|.|| .   .||.|
.........................eelydpelf........................erlgikylri.pvpD.gsaplledfdeflefieea.dkggpv

LVHCMVGVSRSAT-VCIAECMRYLQCDLASAYLFVRVRRLnviIQPNLFFVYELFKWWKKHY
||||. |..|..| |..| .|..|...|. |. .|| .|    |.||  |.. |  ......
lvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp...inpnpgfieqleqyefile
0043147 (Phosphotyrosine protein) phosphatases II 585-775 6.8e-24 79.9 In-house 18-154 (172) alignment 
Range on Protein: 585-775
Range on HMM: 18-154/172.0
LPSRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVvswtlnkdkiahpvrphraitmtntnevagnttcnksrnradtvvsdkqenGSNVVISENSGF
 | |.. ...... ..|.. ..||.|||||||.. |                                                      .    | .|.
ipdrfiatqgplrntladfwrmlkelgithivnltel...................................................lydpellerlgi

QICQIENLDDNGKdpLFHQIDKVLDFISN--SEATGGKVLVHCMVGVSRSATVCIAECMRyLQCDLASAYLFVRVRRlnVIIQPNLFFVYELF
|.. .   | .    |. .....|.|| .   .  ||.|||||. ||.|..|...|  |. |...|  |. .|| .|   .. .|  . . | 
qylylpwpDhgvp..llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekR..pgavqnpsqyrfly
0036941 (Phosphotyrosine protein) phosphatases II 569-783 8.5e-23 76.5 In-house 2-281 (297) alignment 
Range on Protein: 569-783
Range on HMM: 2-281/297.0
FMKIPLESNFVNLKGPLPSRILRHLYLGSLDHAQNPALLK----------------------------------------------------------SL
..|.  ...| .|.    ...|..|.||||..|..|. |.                                                           .
llkllekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweq

GITHIVSVGEVVSWTLNKDKIAHPVR-----PHRAITMTNTNEVA----------------GNttcnksrnradtvvsdkqengsnvviSENSGFQICQI
..|.||.. |.|..  .|     |        .  .|.|....                  ||                          .|    .....
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgn..........................gesrtvthfhy

ENLDDNG----KDPLFHQIDKVLDFISNSeATGGKVLVHCMVGVSRSATVCIAECM--------RYLQCDLASAYLFVRVRRLNVIIQPN-LFFVYELFK
 . .|.|     ..|.. |..|.......   ||.|||||. ||.||.|...|..|        .. ..|. .|....| .| ... ... . |.||.. 
tgwpdhgvpespaslldfielvrkvlkll.psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeall

WWKKHYN
.. |...
ellkkkl
0037934 (Phosphotyrosine protein) phosphatases II 587-778 8.6e-23 76.6 In-house 40-241 (243) alignment 
Range on Protein: 587-778
Range on HMM: 40-241/243.0
SRILRHLYLGSL--------DHAQNPALLKSLGITHIVSVGEVVSWTLNKDKIAHP---VRPHRAITMTNTNevagnttcnksrNRADTVVSDKQENGSN
......|.....        |.|..  .|..||||.||.. | |  . .|     |   .  .  .|.....            . .| .|   .    .
iyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllsee............hlddytvrtlllenld

VVISENSGFQICQIENLDD---NGKDPLFHQIDKVLDFISN-----SEATGGKVLVHCMVGVSRSATVCIAECMRYL-QCDLASAYLFVRVRRLN-VIIQ
    .  .......   |    .  ..|   .|.| .||..      . .||.|||||. ||.|..|...|  | .| ..|| .|. ..| .| . ..  
lddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqt

PN-LFFVYELFKWW
|. . |.||. ...
psqyrflyeallel
subfamily_DSP1_pd Subfamily DSP1 691-783 8.7e-23 75.2 In-house 68-158 (163) alignment 
Range on Protein: 691-783
Range on HMM: 68-158/163.0
NLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWWKKHYN
.|.|. |. .   ...|..|| . ....||||.|| .|.|||.|.|.|  |.  .. |  |. ||. ||   ||.||. || .| .. ||  .
kleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrR..siisPnagFvlqLlnyekklll
DSPc Dual specificity phosphatase, catalytic domain 674-777 2.9e-22 73.9 Pfam-A 30-130 (133) alignment 
Range on Protein: 674-777
Range on HMM: 30-130/133.0
S-NvVISENSGFQICQIEnLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVY
. |   ...| ..  .|  ..|. .. .  ..... .||.. |. |.||||||. |.|||||..||  |.. ...| .|| ||. ||   .| ||  |. 
pnn.naikkseieylrip.vedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerr..skispnagflr

ELFKW
.| ..
qLley
DSPc Dual specificity phosphatase, catalytic domain 674-777 2.9e-22 73.9 In-house 30-130 (133) alignment 
Range on Protein: 674-777
Range on HMM: 30-130/133.0
S-NvVISENSGFQICQIEnLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVY
. |   ...| ..  .|  ..|. .. .  ..... .||.. |. |.||||||. |.|||||..||  |.. ...| .|| ||. ||   .| ||  |. 
pnn.naikkseieylrip.vedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerr..skispnagflr

ELFKW
.| ..
qLley
subfamily_DSP10_pd Subfamily DSP10 680-780 1.8e-21 70.7 In-house 55-152 (159) alignment 
Range on Protein: 680-780
Range on HMM: 55-152/159.0
ENSGFQICQIEnLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWWK
|.....  .|. . |..|  | .. .. |.|| .   .| .|||||. |.|||||| ||  |..|.  |  || ||...|   || ||| |. .| .. |
eeealkYkrip.vsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekr..piisPnLnfmGqLlefek

K
.
e
0046846 (Phosphotyrosine protein) phosphatases II 582-778 8.6e-21 69.9 In-house 8-172 (176) alignment 
Range on Protein: 582-778
Range on HMM: 8-172/176.0
KGPLPSRILRHLYLGSLD----------HAQNPALLKSLGITHIVSVGEVVSWTLNKDKIAHP------Vrphraitmtntnevagnttcnksrnradtv
 .. ...|. .|.|||.           .|.. ..||.||||..|.. | |     |    .|      .                              
ldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..............................

vsdkqengsnvvisensgfqICQIENLDDNGKDPLfHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRY-LQCDLASAYLFVRVRRL-NVI
                      .  . .|.|  .|  .....|.|| .    ||.|||||. |..|..|...|  ...  . ..  |. .|| .|  ...
....................qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgav

IQP-NLFFVYELFKWW
  |  . |.||  ...
qtpeQyrflyefelll
subfamily_DSP14_pd Subfamily DSP14 684-786 1e-20 68.3 In-house 50-149 (157) alignment 
Range on Protein: 684-786
Range on HMM: 50-149/157.0
FQICQIeNLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWWKKHYN
..  ..  ..|| .  | .  |.| | | . ...|||.||||. ||||||..|.|  |.| .  |. ||  |. .|   ||.||. |  .| .. || ..
iervkv.pveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaR..piirPNvGFwkqlidyEkklkg

REK
.  
kss
subfamily_DSP12_pd Subfamily DSP12 679-787 1.1e-20 68.5 In-house 44-149 (155) alignment 
Range on Protein: 679-787
Range on HMM: 44-149/155.0
SENSGFQICQIENLDDNGKDPLFHqIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRrlNVIIQPNLFFVYELFKWW
 ...  .  .|. ||.. .| | | .|...|||... ...|.|||||..|||||.|..||  |.. ...| .|. .|.    .  |.||  |.  |  . 
lkkgkvstkfiqilDepeediLsh.ldeavdFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkek..kpeiepNegFleQLklfe

KKHYNREKD
|  .. ...
kmgckvdts
subfamily_DSP8_pd Subfamily DSP8 692-780 9.8e-20 64.7 In-house 67-153 (159) alignment 
Range on Protein: 692-780
Range on HMM: 67-153/159.0
LDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWWKK
. |. .. |   .|| ..||    .. |.||||.. | |||||| ||  |..|. .| .|| ||. .|    |.||| |.  |... |.
vkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekr..ptispnlnflgqLleyeke
0049260 (Phosphotyrosine protein) phosphatases II 587-770 1.1e-19 66.1 In-house 9-140 (152) alignment 
Range on Protein: 587-770
Range on HMM: 9-140/152.0
SRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVVSWTLNKDKIAHpvrphraitmtntnevagnttcnksrnradtvvsdkqengsnvvisensgfqI
 ... ....|. ..|..  .||.||||.||.. | .  .  | .                                                        
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi....................................................q

CQIENLDDNGKDPLFHQIDKVLDFISN-SEATGGKVLVHCMVGVSRSATVCIAECMRyLQCDLASAYLFVRVRRLNVIIQPNLFF
 .  . .|.|  .|   .. .|.||    .  ||.|||||. ||.|..|...|  |. |...|  |. .|| .| .... |.  .
ylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekRpgavpnpgqlr
0042113 (Phosphotyrosine protein) phosphatases II 573-775 4e-19 64.5 In-house 20-239 (245) alignment 
Range on Protein: 573-775
Range on HMM: 20-239/245.0
PLESNFVNLKGPLPS--------------RILRHLYLGSLDHAQNPA----LLKSLGITHIVSVGEVVSWTLNKDKIAHPV-------------------
|.... | |. . ..              || .......  ......    .|..||||.||.. | .    .|     |                    
pydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehl

--RPHRAITMTNTNEvagnttcnksrnradtvvsdkqengsnvvISENSGFQICQIENLdDNGKDPLFHQIDKVLDFISNSEA--TGGKVLVHCMVGVSR
    .| ...||. .                               .  .......    |.|  .|  .....|.|. .  |   .|.|||||. ||.|
ddytvrtlevtnlgd.............................desrevihyhylpwp.dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgR

SATVCIAECM-----RYLQCDLASAYLFVRVRRLNVI-IQPNLFFVYELF
..|...|  |     ..|  .| .|. ..| .| ... ..  . |.||. 
tGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
0051082 (Phosphotyrosine protein) phosphatases II 587-772 7.8e-19 63.2 In-house 9-145 (151) alignment 
Range on Protein: 587-772
Range on HMM: 9-145/151.0
SRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVVSWTLNKDKIAHPVrphraitmtntnevagnttcnksrnradtvvsdkqengsnvvisensgFQI
|..  .||...  .|.. .|||.|||..||.. . . .  ...                                                      ...
syvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelg................................................iev

CQI--------EnlddngkdpLFHQIDKVLDFISNSEAT-GGKVLVHCMVGVSRSATVCIAECMRyLQCDLASAYLFVRVRRLNVIIQPNLFFVY
..|                  | . .| ||.|..  ... .|.|||||. |..|..|.... .|  |...|..|. ..| .| .|.. .. |...
lhipildwpdpg.........lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfq
0036282 (Phosphotyrosine protein) phosphatases II 587-766 1e-17 59.9 In-house 13-156 (174) alignment 
Range on Protein: 587-766
Range on HMM: 13-156/174.0
SRILRHLYLGSLDHAqNPALLKSLGITHIVSVGEVVSWTLNKDKIAHPVrphraitmtntnevagnttcnksrnradtvvsdkqengsNVVISENSGFQI
|.|...|..|.  .| . ..||.||||..|.. | . . | |     |                                        .    |..|.|.
syitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpe.......................................lredlerlgiqy

CQIENLDDNGKDPLFhqIDKVLDFISNSEAT--GGKVLVHCMVGVSRSATVCIAECMRYLQC-DLASAYLFVRVRR---LNVIIQP
...   |..  |     ......|. .  .   ||.|||||. ||.|..|...|  | .... .|  |. .|| .|    .... |
lylpwpDhgvpdlsi..llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtp
subfamily_DSP6_pd Subfamily DSP6 679-778 1e-17 58.1 In-house 55-151 (158) alignment 
Range on Protein: 679-778
Range on HMM: 55-151/158.0
SENSGFQICQIEnLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNviIQPNLFFVYELFKWW
 |.  ..  ||  ..|. .  | . . . ..|| ..  .  ||||||. |.||| ||..|  |..|.. | .|| .|. |. |  | ||. |.  | .. 
eesgelkylqip.iedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksn..isPnfnfmgqlldfe
subfamily_Slingshot_pd Subfamily Slingshot 684-775 2.9e-17 56.6 In-house 63-151 (169) alignment 
Range on Protein: 684-775
Range on HMM: 63-151/169.0
FQICQIENLDDNgKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELF
|. ..|   |.. .. |... ..  .||... ..| |||||| .||||||.. ||  |.  ...| .|. .|. ||   .|.||  |.  | 
feylnirvydee.etdllkywnetykfiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerr..svikPnkgflkqle
subfamily_DSP19_pd Subfamily DSP19 682-776 3.4e-17 57.2 In-house 54-145 (152) alignment 
Range on Protein: 682-776
Range on HMM: 54-145/152.0
SGFQICQIENLDDNGKDpLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNviIQPNLFFVYELFK
. |....|| ||.. .| | ......|||| ..  . | |||||  ||||||.| ||  |.  . .| .|.  ||  | .  |.||  |.  | .
kdftylsieilDlpetd.llsylkealdFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpc..ikPneGFikqLke
subfamily_DSP15_pd Subfamily DSP15 587-786 6.7e-17 56.0 In-house 3-144 (151) alignment 
Range on Protein: 587-786
Range on HMM: 3-144/151.0
SRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEvvswtlnkdkiahpvrphraitmtntnevagnttcnksrnradtvvsdkqengSNVVISENSGFQI
|..|. |||| .  ... .|||   ||||.|| .                                                     ..  . ..  ...
skvlpglylgnfrdskdeelLkeknithilsvhd.....................................................nakkllkdieYkc

CQIenlDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWWKKHYNREK
 ..   .|  .  | . ...  .|| ..   ...|||||..|||||.|...|  |  .. .   |  ... .|   . .||. |   | .. |.. . ..
iaa...sDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaR..svanPnfGfkrqlkeyektklkeyr
0040438 (Phosphotyrosine protein) phosphatases II 671-784 2.1e-16 55.5 In-house 122-281 (317) alignment 
Range on Protein: 671-784
Range on HMM: 122-281/317.0
ENG---------------------SNVVISENSGFQICQIENLDDNG--------------KDPLFH-QIDKVLDFISNSEAT----GGKVLVHCMVGVS
|.|                      .. . |..|... ..|  |...               |  .   .| .|||..  ..     ||.|||||. ||.
elgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvg

RSATVCIAECM-----RYLQCDLASAYLFVRVRRLNVIIQPNL-FFVYELFKWWKKHYNR
|..|...|..|     .. ..|. .|. ..| .| ...  |.   |.|..  .. |... 
RtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrklt
0040439 (Phosphotyrosine protein) phosphatases II 577-772 3.5e-16 55.0 In-house 55-236 (249) alignment 
Range on Protein: 577-772
Range on HMM: 55-236/249.0
NFVNLKGPLPSrilrhlylgslDHAQNPALLKSLGITHIVSVGEVVSWTLNK-----------------------DKiaHPVRPHRAITMTNTNevagnt
.|.  .||||.             . .  .|. ||||.||.. . |    .|                       ..  ..   .| ...||.       
rfiatqgPlpe...........tvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvev..kddytvrtleltnly......

tcnksrnradtvvsdkqengsnvvisENSGFQICQIENLDDNgKDPLFHQIDKVLDFISNSEA------TGGKVLVHCMVGVSRSATVCIAECM-----R
                          ... ... .|  .|    . .   .. .||||   .       .||.|||||. ||.|..|...|  |     .
..........................dgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlek

YLQCDLASAYLFVRVRRLNviIQPNLFFVY
.|. || .|. ..| .| .  . .|. . .
elgvdleeavkllrsqRpg..avqnpeqyr
0045450 (Phosphotyrosine protein) phosphatases II 605-774 3.5e-16 55.3 In-house 125-299 (307) alignment 
Range on Protein: 605-774
Range on HMM: 125-299/307.0
ALLKSLGITHIVSVGEVVSwtlnkdkiahpvrphraitmtntnevagnttcnK-------SRNRADTVVSDKQENGSNVVISENSGFQICQIENLDDNGK
 .|. .|.|.||.. | |                                  .            ....  ..    .. ... .|... ..|  | .|.
rmlweqgvtvivmltelve.................................lgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgt

D----------------PLFHQIDKVLDFISNSEA------TGGKVLVHCMVGVSRSATVCIAECMRYLQ--------CDLASAYLFVRVRRLNVIIQPN
.                 .   .. .||||   ..       ||.|||||. ||.|..|...|  | ..         .|| .|. ..| .| ...  |.
gesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpe

-LFFVYEL
 . |.||.
qyrflyea
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 689-780 4.9e-16 52.1 In-house 52-140 (145) alignment 
Range on Protein: 689-780
Range on HMM: 52-140/145.0
IENLDDNGKDpLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNViiQPNLFFVYELFKWWKK
|   | .  | |   .|.| |||      |  |.|||| ||||| || .|  |.| .  |. |   || .||     ||. |. .|..  |.
itaedlesyd.lsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrlla..ypnvtflknllnlekq
0039614 (Phosphotyrosine protein) phosphatases II 638-781 2.8e-15 52.0 In-house 38-291 (297) alignment 
Range on Protein: 638-781
Range on HMM: 38-291/297.0
HRAITMTNTNEVAGNTTCNKSRNRADTVV-------SDKQ---------------------------------------------ENG------------
.  .   . . . ..  .||..||   ..         |                                              |.|            
feellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklve

---------------------SNVVISENSGFQICQIE----------------NLDDNGKDPLFHQIDKVLDFISNSEA---TGGKVLVHCMVGVSRSA
                      .. . ...|. . ..|                .  |.|  |.. .....|... .  |    ||.|||||. ||.|..
lgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtG

TVCIAECM-----RYLQCDLASAYLFVRVRRLNVIIQP-NLFFVYELFKWWKKH
|...|  |     .. . |. .|. ..| .| ...  |  . |.|.. ... |.
tfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
subfamily_MKPLT_pd Subfamily MKPLT 691-778 5.4e-15 49.3 In-house 72-157 (164) alignment 
Range on Protein: 691-778
Range on HMM: 72-157/164.0
NLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWW
...|. .. |   .... .|....  .||.|||||  |.|||..| .|  ... .  |  || ... ||   |..||  |. .| |. 
kvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerr..sivapnrGflkqlakfe
subfamily_MKPLV_pd Subfamily MKPLV 691-778 5.4e-15 49.3 In-house 72-157 (164) alignment 
Range on Protein: 691-778
Range on HMM: 72-157/164.0
NLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELFKWW
...|. .. |   .... .|....  .||.|||||  |.|||..| .|  ... .  |  || ... ||   |..||  |. .| |. 
kvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerr..sivapnrGflkqlakfe
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 678-781 3.1e-14 46.6 In-house 50-152 (154) alignment 
Range on Protein: 678-781
Range on HMM: 50-152/154.0
ISENSGFQICQIENLDDNGKDpLFHQIDKVLDFISNSE--ATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnVIIQPNLFFVYELF
| .   .. ...|  ||   | . ...||...|| ..      .|||||.  ||||||.. |.  |  |.  |  |. ...  |   ||.||  |.  | 
indgfiieylnlelfddvnfd.iiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdklkislslalellkdsr..yiikPnqGflkqle

KWWKKH
.. |. 
ifekel
0043336 (Phosphotyrosine protein) phosphatases II 607-773 3.4e-14 48.5 In-house 108-271 (278) alignment 
Range on Protein: 607-773
Range on HMM: 108-271/278.0
LKSLGITHIVSVGEVVSWTL--------------------NKDKIAHPVRPHRAITMTNTNEVagnttcnksrnradtvvsdkqengsnvviSENSGFQI
.. ||.|.||.. | | .                      ... . ..   .| ...||. .                               .  . ..
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdg.............................esrtvthy

CQIENLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECM-----RYLQCDLASAYLFVRVRRLNVIIQPNL-FFVYE
. .   |..  ..| . .| . ....  |  .|.|||||. ||.|..|..... .     ...  || .|. ..| .| . .  |.   |.||
hylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflye
0051429 (Phosphotyrosine protein) phosphatases II 577-770 5.6e-14 47.9 In-house 8-216 (272) alignment 
Range on Protein: 577-770
Range on HMM: 8-216/272.0
NFVNLKGPlPSRILRH-LYLGSLD---HAQNPALLKSLGITHIVSVGEVVSWTLNK-DKIAHpvrphraitmtntnevagnttcnksrnradtvvsdkqe
|.  ..|.  ...... ||...      |.. . ||.|||..||.. ...    .| |. ..                                      
Nardvggy.grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywp......................................

ngsnvvisensGFQICQIENLDDNGKDPLFHQ--------------------------------------------------IDKVLDFISNseatGGKV
           |......  |||   ..|...                                                  . ..|... .    ||.|
...........girylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld....ggpv

LVHCMVGVSRSATVCIAECMRyLQCD--------------LASAYLFVRVRRLNVIIQPN-LFF
||||. |..|..||. .  .  |. .              |. |.  .| .| ...  .  . |
lvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylf
0047943 (Phosphotyrosine protein) phosphatases II 694-777 1.2e-13 46.7 In-house 178-270 (273) alignment 
Range on Protein: 694-777
Range on HMM: 178-270/273.0
DNGKDPLFHQIDKVLDFISNSEA---TGGKVLVHCMVGVSRSATVCIAECM-----RYLQCDLASAYLFVRVRRLNVIIQPN-LFFVYELFKW
|.|  | . .. . .... .  .    .|.|.|||. ||.|..|.......     .. . |. .|. ..| .| .... |. . |.||.. .
dhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
0051299 (Phosphotyrosine protein) phosphatases II 694-777 8.4e-13 43.9 In-house 194-284 (288) alignment 
Range on Protein: 694-777
Range on HMM: 194-284/288.0
DNG-KDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECM-----RYLQCDLASAYLFVRVRRLNVIIQP-NLFFVYELFKW
|.|  | . . .| . ....  ...|| |.|||. ||.|..|.......     .   .|. .|. ..| .| .... |  . ||||.  .
dhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealle
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 691-779 1.2e-12 41.5 In-house 59-145 (148) alignment 
Range on Protein: 691-779
Range on HMM: 59-145/148.0
NLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNviIQPNLFFVYELFKWWK
.|||. |  |    ... .|... .. |..||||. .|||||. . ..  ... .  |  |. .|. .|    ..||| |.  | .. .
aldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrvslkealalvkskrry..vdpnlgfLkqLaeleq
subfamily_DSP3_pd Subfamily DSP3 684-777 1.5e-12 41.4 In-house 63-153 (162) alignment 
Range on Protein: 684-777
Range on HMM: 63-153/162.0
FQICQIENlDDNGKDPLFHQIDKVLDFISNSEAT-GGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRlnvIIQPNLFFVYELFKW
.. . .|  ||. .  | .  ... .|| .. ..  |||||||.||||||||. .|  | . . .| .|   || .|    |.||  |.  | . 
ikylGlev.dDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkkR...eilPneGFlkqLael
0046845 (Phosphotyrosine protein) phosphatases II 698-780 1.5e-12 43.0 In-house 181-275 (284) alignment 
Range on Protein: 698-780
Range on HMM: 181-275/284.0
DP----LFHQIDKVLDFISNsEATGGKVLVHCMVGVSRSATVCIAECMRYL--------QCDLASAYLFVRVRRLNVIIQPN-LFFVYELFKWWKK
 |    |.. ...| ....|   .||...|||. ||.|..|....... ..         .|. .|. ..| .| . . ..  . ||||.. .. |
ppspedlleflrlvrellen.lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylk
subfamily_STYX_pd Subfamily STYX 689-777 1.9e-12 40.6 In-house 67-153 (166) alignment 
Range on Protein: 689-777
Range on HMM: 67-153/166.0
IENLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLnvIIQPNLFFVYELFKW
. .. ||  . .   . .| .|| .|  .|||||||   |.||||.. ||  |        .|...|. ||.   |.||  || .| ..
vldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrf..cinpnegfvsqlkey
0038934 (Phosphotyrosine protein) phosphatases II 694-778 2.7e-12 42.2 In-house 89-173 (194) alignment 
Range on Protein: 694-778
Range on HMM: 89-173/194.0
DNGKDPLFHQIDKVLDFISN--SEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPNlfFVYELFKWW
| |  | . .... ||..    .| .||.|.|||. |..|..|...|  . .|....  |. ..| .| ..|....  .. .|.|..
ddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqd..yleallkry
subfamily_STYXL1_pd Subfamily STYXL1 686-782 4e-12 39.6 In-house 61-154 (157) alignment 
Range on Protein: 686-782
Range on HMM: 61-154/157.0
ICQIeNLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNviIQPNLFFVYELFKWWKKHY
. .| ...|. .  |....... .|| . . .|  |||    |.||||.| ||  | . .  | .|| ...  . |  ..||  ||  | .| |. .
llhi.avedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCken..vkPnrafveqlseWekqll
subfamily_LRR-DSP_pd Subfamily LRR-DSP 684-781 6.8e-12 39.0 In-house 164-258 (263) alignment 
Range on Protein: 684-781
Range on HMM: 164-258/263.0
FQICQIENLDDNGKDPLFHQIDKVLDFISNSEATGGkVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNviIQPNLFFVYELFKWWKKH
|.   |....|  .  ..   ...  || .    || |||||  |||||.|. |.  |.. .  .  |. .|  .| .  ||||  |.  | |. || 
fkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpr..iqPnpGfkdqlkkyekkl
subfamily_MSG5_pd Subfamily MSG5 705-777 7.8e-12 38.6 In-house 86-156 (165) alignment 
Range on Protein: 705-777
Range on HMM: 86-156/165.0
DKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNviIQPNLFFVYELFKW
 ..   |  ... . |.||||  |.||||.. .|  |.| .  |  ||  .. .  .  |.|.. ....|..|
srltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvadd..ispsiglifqlmew
0050432 (Phosphotyrosine protein) phosphatases II 703-777 9.2e-12 40.4 In-house 215-297 (308) alignment 
Range on Protein: 703-777
Range on HMM: 215-297/308.0
QIDKVLDFISNSEAT--GGKVLVHCMVGVSRSATVCIAECM-----RYLQCDLASAYLFVRVRRLNVIIQPNL-FFVYELFKW
... .|||.   . .  ||...|||. ||.|..|.......     .   .|. .|. ..| .| .... |.  .|.|..  .
speilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralle
PTEN_1 679-766 3.2e-11 38.4 In-house 90-179 (196) alignment 
Range on Protein: 679-766
Range on HMM: 90-179/196.0
SENSGFQICQIENLDDNgKDPLFHQIDKVLDFISNSEA--TGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQ-P
 ..||..  ...  |.. . .| . .| . .||.   .   |..|||||  |..||.||..|  |.. . .   |  .|| .| .. .. |
ffksgveylhfpieDhg.apslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnsp
subfamily_PTPMT1_pd Subfamily PTPMT1 681-767 2.4e-10 35.1 In-house 71-156 (171) alignment 
Range on Protein: 681-767
Range on HMM: 71-156/171.0
NSGFQICQIENLdDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPN
. | .. |..   |  . | .... | ..||..   .| .| |||  | .||||. ..  |   .... .|  ... .|  . .. .
klgveqlqlatv.DfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakk
subfamily_LRR-DSP_pd Subfamily LRR-DSP 578-621 1e-07 25.3 In-house 112-156 (263) alignment 
Range on Protein: 578-621
Range on HMM: 112-156/263.0
FVNLKGPLPSRILRHLYLGSLDHAQNPALLKSLGITHI-VSVGEV
.. |.  .|. |. .|.||.|| |.| ..||.||.||| ..|...
litlvssvPdeiidklflGgldsannksilkdlgvthillavadf
subfamily_DSP1_pd Subfamily DSP1 584-620 1.1e-06 22.9 In-house 17-52 (163) alignment 
Range on Protein: 584-620
Range on HMM: 17-52/163.0
PLPsRILRHLYLGSLDHAQNPALLKSLGITHIVSVGE
|   .|| .|||||  .| |  .|||||||.|. | .
Pve.kildfLylGsetvasnleiLkslgitailnvsk
PTPc_DSPc_SM00012 699-741 3.1e-06 22.7 In-house 21-62 (105) alignment 
Range on Protein: 699-741
Range on HMM: 21-62/105.0
PLFHQIDKVLDFISNSEAtGGKVLVHCMVGVSRSATVCIAECM
.... ...| .. ..||  .. |.|||  ||.|..|.. ....
silellravkknknkses.skpvvVhCsaGvgRtgtfvaldil
Y_phosphatase Protein-tyrosine phosphatase 665-741 4.9e-06 21.5 Pfam-A 122-193 (235) alignment 
Range on Protein: 665-741
Range on HMM: 122-193/235.0
VVSDKQENGsnvvisENSGFQICQIENLDDNGKDplfHQIDKVLDFISNSEATG----GKVLVHCMVGVSRSATVCIAECM
 ...|.|.       |.  ..  ...|  |.|      . ...||.| . | .     |.|.|||. ||.|..|.. ....
elkkkkees......ekrevkqlhytnWpdhgvp...espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldil
Y_phosphatase Protein-tyrosine phosphatase 665-741 4.9e-06 21.5 In-house 122-193 (235) alignment 
Range on Protein: 665-741
Range on HMM: 122-193/235.0
VVSDKQENGsnvvisENSGFQICQIENLDDNGKDplfHQIDKVLDFISNSEATG----GKVLVHCMVGVSRSATVCIAECM
 ...|.|.       |.  ..  ...|  |.|      . ...||.| . | .     |.|.|||. ||.|..|.. ....
elkkkkees......ekrevkqlhytnWpdhgvp...espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldil
0048567 (Phosphotyrosine protein) phosphatases II 704-777 8.2e-06 20.3 In-house 60-136 (157) alignment 
Range on Protein: 704-777
Range on HMM: 60-136/157.0
IDKVLDFISNSEATGGKVLVHCMVGV---SRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPNLFFVYELFKW
| |. .|..  | .|... |||  |    .|.||.. . .. .|. . . |. ..|. | . .. .   ... |...
ilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslynl