Gene OCA4 in Saccharomyces cerevisiae

Synonym: YCR095C, OCA4

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP008_AA protein Get Run
ScerP008_AA_0-191 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Y_phosphatase2 Tyrosine phosphatase family 62-219 3.6e-48 155.5 Pfam-A 1-164 (165) alignment 
Range on Protein: 62-219
Range on HMM: 1-164/165.0
VLRMSDFSAAAVPVKSSSVSNANLYSNNNStLSLQEEKKKSTANGSQNSTTG-DPVIQEELAYHLTDNDD-LMLIKSTCLKRTFKTLLNVDNYNVLLVD-
......|||.......||...|...|...| |.|......|... ||..... ..  ..........|.. |. |||..||...|.|||..||.|||.. 
lvpplnFsaveselyrssyprasnfsflks.LkLktiislspeeesqdelqfleeekiklyhiaiesnkeelveiksdllkkalklllnkenypvllhck

----KTALVIGILRKIQKWNIASIINEYRLFSGKNRNYFAETFLEIINIEIEQEKDNKTIVDNKA
    .|.||||.|||.|||..|||.||||.|||.......|.|.|....|.|.||.||.....|.
rGkhrtglvigclRklqkWslasilnEyrrFsgskkrivdeefienfdselevekknkklkvlks
subfamily_OCA_pd Subfamily OCA 2-199 1.1e-38 123.3 In-house 144-279 (282) alignment 
Range on Protein: 2-199
Range on HMM: 144-279/282.0
LVPPANFGIAEE--------GIYRCSKVETLNLSFL-ETLNLKTAIFIGGQE-PSKFFKDFFTRSSIKWIVLRMsdfsaaavpvksssvsnanlysnnns
||||.||...||        |..|....|..||.|| ..|.||||......| ......||...|.||...||.                          
lvpprnfslveeykdkpvisgllrlllpeeenlpfLidrlglktaliLdaeeveretiadflasseiklvslrn..........................

tlslqeekkkstangsqnsttgdpviqeelayhltdnddlmlikstclkRTFKTLLNVDNYNVLL--VDKTALVIGILRKIQKWNIASIINEYRLFSG-K
                                                 ...|.||..|||.|.|  ..||..|...|||..|....||..||..|.. .
.................................................evlkdlldndnyavelscqaktdtvlkvLrkdkkygstsiyleyigFtled

NRNYFAETFLE
....  . . |
qeslksillie
0051082 (Phosphotyrosine protein) phosphatases II 1-191 3.9e-16 54.5 In-house 1-137 (151) alignment 
Range on Protein: 1-191
Range on HMM: 1-137/151.0
MLVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEPSKFFKDFFTRSSIKWIVLRMSDFSAAAvpvksssvsnanlysnnnstlslqeekk
.|... ||.  ..|.||..     .| .|..|..|| . . . |. ......... .|... . . |...                              
plsdyinfsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpg............................

kstangsqnsttgdpviqeelayhltdnddlMLIKSTCLKRTFKTLLNVDNYNVLL-----VDKTALVIGILRKIQKWNIASIINEYRLFSGKNRN
                               . .    ... .. ||. .|..||      .. |....................||||. .   .
...............................lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvq
Y_phosphatase2 Tyrosine phosphatase family 2-66 5.1e-11 34.6 Pfam-A 1-65 (165) alignment 
Range on Protein: 2-66
Range on HMM: 1-65/165.0
LVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEPSKFFKDFFTRSSIKWIVLRMS
|||| ||. .|...|| |  .  |.|||..|.||| | .  .| |.  . |..   || . . ..
lvpplnFsaveselyrssyprasnfsflksLkLktiislspeeesqdelqfleeekiklyhiaie