Synonym: YDL230W, PTP1
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 22-333 | 1.1e-131 | 433.8 | In-house | 6-348 (350) | alignment | ||
Range on Protein: 22-333
Range on HMM: 6-348/350.0
IQNQEDGRLREATNGTVNSRWSLGVSIE-PRND----------ARNRYVNIMPYERNRVHLK-----------TLSGNDYINASYVKVNVPGQSIEPGY-
.| .. .| . |.||.||.||....| |.|| |.|||.||.|||..||.|| .||.||||||.|.|.......|.|..
vqkrsklkliitknstvksrlsLesdsespsnDvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfk
YIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRGGVDD-TVRIASKWESPGGANDMTQFPSDLKIEFV------NVHKVKDYY
|||||.|...|.|.|......| ...||...|..||.|.||||.||..|..|| ||..|||||...|.||......|.|.|.. .....||..
YiatqaPlpstvddfykvilln...kvkvilsltsdvelnlekcyrYWqegsydditvklaskwenimgindsslysadvkkeasdndnisddndlkdnn
TVTDIKLTPTDPLVgpvktVHHFYFDLWKDM---NKPEEVVPIME--------LCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITE
..|.|.|...||.| |.......|||. ..||......| |.|.||. |.|..||.||||||||||||...||.|..|.....|.|.
sltaitlaasdPyv.....vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltk
RSRHSDRATEeyTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSV
.||..|.|.. |||||..||..||.||..|||..|||.|||.|......|.
esrkldvaak..trDlisiivnelrkqrismvqnldqfifiYeallfyfaLrk
|
|||||||||
| DSPc_SM00195 | 40-326 | 9.1e-72 | 236.9 | In-house | 16-259 (263) | alignment | |||
Range on Protein: 40-326
Range on HMM: 16-259/263.0
SrwSLGVSIEPRNDARNRYVNIMPYERNRVHLKTL---SGNDYINASYVKVNvpgqsIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVE
. . .....| ..||| ||.||...||.||. .|.|||||.|.|.. .. |||||||. .|...||.|.... . .|||.| .|
k..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.....nkkkkyIatQgPlpstvedFWrmvwee...kvkiivmlteeee
YNREKCYQYWPRGGvddtvriaskwespggaNDMTQFPsDLKIEFVNVHKVKDYYTVTDIKLTPTDPlvGPVKTVHHFYFDLWKDMNKPEEV---VPIME
..|||..|||. .. ..| ......|.|.|.|| .......|| ... ..|... . |.| . |.. . ...
ngkekcdrywpees.................ggketfg.kisvklvevekkkdeiilrtleltkegk..eetrkvtqyqyknWpdhgvpdstksvlellr
LCAHSHSLNsrGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNitersrhsdrateeytrDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
. .|.| . .||.|||||||||||||...| ... . |. . |..|| .||.||..||||..|.||||.|.
avkksksts..sgpivVhCsaGvgRtgtfvtidiilskleeekk.................vdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
| PTPc_SM00194 | 40-326 | 9.1e-72 | 236.9 | In-house | 16-259 (263) | alignment | |||
Range on Protein: 40-326
Range on HMM: 16-259/263.0
SrwSLGVSIEPRNDARNRYVNIMPYERNRVHLKTL---SGNDYINASYVKVNvpgqsIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVE
. . .....| ..||| ||.||...||.||. .|.|||||.|.|.. .. |||||||. .|...||.|.... . .|||.| .|
k..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.....nkkkkyIatQgPlpstvedFWrmvwee...kvkiivmlteeee
YNREKCYQYWPRGGvddtvriaskwespggaNDMTQFPsDLKIEFVNVHKVKDYYTVTDIKLTPTDPlvGPVKTVHHFYFDLWKDMNKPEEV---VPIME
..|||..|||. .. ..| ......|.|.|.|| .......|| ... ..|... . |.| . |.. . ...
ngkekcdrywpees.................ggketfg.kisvklvevekkkdeiilrtleltkegk..eetrkvtqyqyknWpdhgvpdstksvlellr
LCAHSHSLNsrGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNitersrhsdrateeytrDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
. .|.| . .||.|||||||||||||...| ... . |. . |..|| .||.||..||||..|.||||.|.
avkksksts..sgpivVhCsaGvgRtgtfvtidiilskleeekk.................vdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 37-328 | 6.3e-70 | 231.1 | In-house | 13-273 (284) | alignment | ||
Range on Protein: 37-328
Range on HMM: 13-273/284.0
TVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG----NDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVT
||. .|| |.. | | .|||..|.||...||.||.|.| .||||||||.. . .. . .||||||. .|.. ||.|.... . ||||.|
tvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq...nvrvIVmlt
PLVEYNREKCYQYWPRGgvDDTVRIaskwespggandmtqfpSDLKIEFVNVHKvKDYYTVTDIKLTPTdPLVGPVKTVHHFYFDLWKDMNKPEEVVPIM
.|||..||||.|||| ...... |.......... ||.|||. ..||.. . |...||.||.. | |.. |... ...
elvengrekcaqYwple..gevlty.................gdftvtllseev.kddytvrtleltnl.gytgesrtvthfhytswpdhgvppspedll
ELCAHSHSLNSR---GNPIIVHCSAGVGRTGTFIALDHLMHDTLDFK---NITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
|.. ..|... |.||.|||||||||||||||||.|.. . ... ....| .||.||. |||| .|..|.|.|.
eflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvd.................vleavkrlreqRpgmvqtleqyrfvyeall
YL
..
ey
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 45-328 | 1.1e-68 | 227.2 | In-house | 61-298 (308) | alignment | ||
Range on Protein: 45-328
Range on HMM: 61-298/308.0
GVSIEPRNDARNRYVNIMPYERNRVHLkTlSGNDYINASYVKVNVpgqSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
|. |.| .|||..|.||...||.| .|.||||||||.. . |. | .||||||. .|.. ||.|.... . ||||.| |||..||||.|
svallpenkdkNrykdilpydhsRVkl.d.egsdYInAsyvdgys...sklprkfIatqgPlpntvedFwrmvweq...nvrvIvmLtklvengrekcaq
YWPRGGVDDTVRIaskwespggandmtqfpSDLKIEFVNVHKvKDYYTVTDIKLTPTDPLvgPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNsR
||| ...... ........... .|.|||. ..||... ...||.||.. |.|.. |... ...... . .. . .
Ywplelgggsley.................gkftvtllseev.lddytvrtleltnlgdg..esrtvthfhytnWpdhgvPpspeilldflelvrksl.p
GNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
|.||.|||||||||||||||||.|.. .... ....| .||.||. ||||..|.||.|.|. ..
ggpivVHCsaGvGRtGtfialdllleqlekeggvd.................vfeavkklReqRpgmvqtpeqylflyralley
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 43-327 | 9.3e-67 | 220.8 | In-house | 40-284 (288) | alignment | ||
Range on Protein: 43-327
Range on HMM: 40-284/288.0
SLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKVnvpgqSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNR
.| ... | | .|||..|.||...||.|..|.| .|||||||... . .||||||. .|.. ||.|.... . ||||.|.|||..|
tlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidg.....ynlkrkfIatqgPlpntvedFWrmvweq...nvrvIvmltklvelgr
EKCYQYWPRggvDDTVRIaskwespggandmtqfpSDLKIEFVNVHKvKDYYTVTDIKLTPTDP--LVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAH
|||.|||| .... . |.......... .|.|||. ...|..| | ..||.||.. | |.. |. . ...... .
ekcaqYwpl...ggslty.................gditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrl
SHSL-NSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
.. .|.|.|..|||||||||||||||||.|.. . . .. ....| .||.||. |||| .|..|.|.|. .
vrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvd.................vleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 42-328 | 2.8e-64 | 212.7 | In-house | 33-275 (317) | alignment | ||
Range on Protein: 42-328
Range on HMM: 33-275/317.0
WSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVkvNVPGQSIEpgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYN
.. |.. | | .|||..|.||...||.|. |.| .|||||||| ..| .. . .||||||. .|.. ||.|.... . ||||.|.|.|..
dtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyv..dgpnlkrk...fIatqgPlpntvedFwrmvweq...gvtvivmLteleelg
REKCYQYWPRggvDDTVRIAskwespggandmtqfpsDLKIEFVNVHKvKDYYTVTDIKLTPTdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHS
||||.|||| ..|. . |.......... ....|.. ...... ... ||.||.. | |.. |. .. ...
rekcaqYwpl...getltyg.................dftvtllseee.lagitlrtlevedl..gdsesrtvthfhytgWpdhgvppspdllldfleav
HSLNSR-GNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
.. ... |.|..|||||||||||||||.. ... .... .|..| .||.||...||| .|. |.| |. ..
realedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvd.................veeavkelreqRpgavqtpeqyrflydalley
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 38-328 | 4.7e-64 | 212.4 | In-house | 41-303 (307) | alignment | ||
Range on Protein: 38-328
Range on HMM: 41-303/307.0
VNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG----NDYINASYVKVNVP---GQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVM
| .. .. | | .|||..|.||...||.|..|.| .||||||||.|... . . . .||||||. .|.. ||.|.... . ||||
vfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweq...gvtvivm
VTPLVEYNREKCYQYWPRGGVDDTVRiaskwespggandmtqfpsDLKIEFVNVHKvKDYYTVTDIKLTPTdPLVGPVKTVHHFYFDLWKDMNKP---EE
.|.|||..||||.|||| | | . ........... .|.|||. ...|.. |.. ||.||.. | |.. | ||
ltelvelgrekcaqywPdegeeltyg...................nftvtllseeh.ldgytvrtlevtdl.dgtgesrtvthfhytgwpdhgvppsfee
VVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKN---ITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
.. ..|.. . .. ...|.|..|||||||||||||||.. ... . . .. ....| .||.||...||. .|. |.|.|
lldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvd.................lleavkllreqRpgavqnpeqyrflyea
AKYL
...|
llel
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 46-329 | 1.8e-62 | 206.9 | In-house | 50-289 (297) | alignment | ||
Range on Protein: 46-329
Range on HMM: 50-289/297.0
VSIEPRNDARNRYVNIMPYERNRVHLKTLSG----NDYINASYVkvnvPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNReK
.. | | .|||..|.||...||.||.. | .|||||||| .| .. . .||||||. .|.. ||.|.... . ||||.|.|||..| |
iallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyv....dgydlltrkfIatqgPlpetvedFwrmvweq...gvtvivmLtklvelgr.k
CYQYWPRGgvddtvriaskwespggaNDmtqFPSDLKIEFVNVHKvKDYYTVTDIKLTPTDPLvgpvKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSL
|.|||| . |.......|.. .|.|||. ...|.... .||.|| . | |.. |. . ..|.. ..
caqywpee..................gg...tygdftvtllkveh.ldgytvrtlevtnnges....rtvthfqytgwpdhgvppslellleflelvrea
NS---RGNPIIVHCSAGVGRTGTFIALDHL-----MHDTLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLN
.. .|.|..|||||||||||||||.. . . ..| ....| .||.||...||| .|. |.|.|...|
laelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvd......................vleavkelreqRpgavqtpsqyrflydallell
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 45-327 | 1.4e-61 | 203.8 | In-house | 31-270 (273) | alignment | ||
Range on Protein: 45-327
Range on HMM: 31-270/273.0
GVSIEPRNDARNRYVNIMPYERNRVHLkTLSGNDYINASYVkvNVPGQSIEpgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
|.. |.| .||| .|.||...||.| . .|.|||||||| ... .. . .||||||. .|.. ||.|.... . ||||.|.||| .||||.|
svallpenkdknrykdilpydhsrvkl.gdggsdyinAsyv..dgynlkrk...fiatqgPlpntvedfwrmvweq...nvrviVmLtelvelgrekcaq
YWPRGgvddtvriaskwespggANDMTQFPSDLKIEFVNVHKvKDYYTVTDIKLTPTDplVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS-
||| ..... ........... ||.|||. ..||... | ..||.||.. | |.. |. . ...|.. . .. ..
Ywple.................ggelsltygkftvtllseet.kddytvrtleltnlg..tgesrtvthfhytgwpdhgvppslesllefielvrkalea
--RGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
...|..|||||||||||||||||.|.. .... ....| .|||||. |||| .|..|.|.|. .
lpsngpvvVHCsaGvgRtgtfialdllldqlekeggvd.................vleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 46-328 | 2.1e-61 | 203.2 | In-house | 33-276 (297) | alignment | ||
Range on Protein: 46-328
Range on HMM: 33-276/297.0
VSIEPRNDARNRYVNIMPYERNRVHLkTLSGNDYINASYVkvNVPGQSIEpgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQY
|.. |.| .||| .|.||...||.| . .|.|||||||| ...... . .||||||. .|.. ||.|.... . ||||.|.|||..||||.||
vallpenleknRykdilpydhtRVkl.ddegsdYinAsyv..dgydlkrk...fIatqgPlpntvedFWrmvweq...nvtvIvmltelvelgrekcaqy
WPRGgVDDTVRIASkwespggandmtqfpsdLKIEFVNVHKV-KDYYTVTDIKLTPTdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS-
|| ..... .......|..| .|.||.. ...|.| |...||.||.. | |.. || . ...... .. ..
wple.egesltygd.................ftvtllsvevvllddytlrtlevtdt..gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkl
--RGNPIIVHCSAGVGRTGTFIALDHL--------MHDTLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
.|.|..|||||||||.|||||.| . .. ..| | ..|..||.||. .||| .|..|.|.| .|
lpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvd......................ileavkklReqRpgavqtleqyrflyeallel
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 46-327 | 3.2e-60 | 199.3 | In-house | 39-275 (278) | alignment | ||
Range on Protein: 46-327
Range on HMM: 39-275/278.0
VSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVkvnvPGQSIEPGyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKC
... | | .|||..|.||...||.|. |.| .|||||||| .| .. .. .||||||. .|.. ||.|.... . .|||.|.|||..|.||
iallpenkdknrykdilpydhsrvklsllggdldsdYinAsyv....dgynvprk.fiatqgPlpetvedFwrmvwel...gvttivmLtelvelgrvkc
YQYWPrggvDDTVRIASkwespggandmtqfpsdLKIEFVNVHKvKDYYTVTDIKLTPtdPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN
.|||| ...... .......... .|.|||.....|. |...||.|... | |.. || . ...... .. .
aqYwp....ggsltygd.................ftvtllkeeh.lddytvrtlevtn..lgdgesrtvthyhylgwpdhgvpeslsllldflkavreal
S-RGNPIIVHCSAGVGRTGTFIALDHLM-----HDTLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
. ...|..||||||||||||||||. |. . ..| .|..| .||.||...||| .|. |.|.|...
edsngpvlVHCsaGvgRTGtfialyllleqlekeggvd......................leeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 49-328 | 4.1e-60 | 198.9 | In-house | 30-271 (278) | alignment | ||
Range on Protein: 49-328
Range on HMM: 30-271/278.0
EPRNDARNRYVNIMPYERNRVHlktlsgnDYINASYVKVNvpgqsiePGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
. | ..|||..|.||...||. |||||||... | .||||||. .|...||.|.... . ||||.|.|||..||||.||||
ylgnldknRykdilpydhsrVk.......dYINAsyidgy.......pkkfIatqgPlpstvadfwrmlwel...gitvivmltelvelgrekcaqywpe
ggvDDTVRIaskwespggandmtqfpSDLKIEFVNVHKVkDYYTVTDIKLTPT--DPLVGPVKTVHHFYFDLWKDMNKPEEV--VPIMELCAHSHSLNS-
...... |......... . |.||......| . . .. .|.|... | |.. |.. .. ||. .. ..
...ggslty.................gdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkl
-------------RGNPIIVHCSAGVGRTGTFIALDHLMHD---TLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMK-MVQTKDQFLFIYHAAK
.|.|..||||||||||||..|.. ... ..| ....| .|||||. .||...|. |.|...
laslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvd......................lleavkelrsqRpglavqnleqyrflyefll
YL
.|
el
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 48-328 | 3e-58 | 192.5 | In-house | 5-242 (245) | alignment | ||
Range on Protein: 48-328
Range on HMM: 5-242/245.0
IEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVkvnvPGQSIEPGyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
. | | .|||..|.||...||.|. .| .|||||||| .| | |. .||||||...|.. ||.|.... . .|||.|...|..|.||.|
llpenkdknrysdilpydhtrvklspdggdldsdyinasyv....dgyritpk.fiatqgPlpetvedfwrmlwel...gittivmLteeeelgrvkcaq
YWPRggvDDTVRIaskwespggandmtqfpSDLKIEFVNVHKvKDYYTVTDIKLTPTdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS-
||| ...... |.......... .|.|||. ...|.. .....|.|... | |.. |. . . ... .. .
ywpl...geslty.................gdftvtllseeh.lddytvrtlevtnl..gddesrevihyhylpwpdhgvpdllellldflefvrkalae
-RGNPIIVHCSAGVGRTGTFIALDHLM-----HDTLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
...|..|||||||||||||||.. .. . ... .|..| .|||||...||| .|. |.|.|...|
dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvs......................leeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 48-327 | 4.4e-58 | 192.0 | In-house | 6-240 (243) | alignment | ||
Range on Protein: 48-327
Range on HMM: 6-240/243.0
IEPRNDARNRYVNIMPYERNRVHLktlSGNDYINASYVKVNvPgqsiepgYYIATQGPTRKTWDQ----FWQMCYHNcplDNIVIVMVTPLVEYNREKCY
. | | .||| .|.||...||.| .|.|||||....| | ..||||||. .|... ||.|.... . ||||.|.|||..||||.
llpenlsknrysdilpydhsrvkl...egsdyinanliyvt.p.......rliatqgPlpetveddlasfwrmlwel...gitvivmltelvElgrekca
QYWPrggvddtvriaS-----KwespggandmtqfpsdLKIEFVNVHKvKDYYTVTDIKLTPtDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHS
|||| . . ......... .|.|||. ..|.. .| .....|.|... | |.. |... ...... .
qywp...........gevtygd................ftvtllseeh.lddytvrtlllen.ldlddltrlvihyhylpwpdhgvPdspedlldfldev
HS---------LNSRGNPIIVHCSAGVGRTGTFIALDHLMHD-TLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMK-MVQTKDQFLFIYHAAKY
.. ...|.|..||||||||||||.||.. ... ..| .|..| .||.||. .||| .|. |.|.|...
refieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvd......................leeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 38-324 | 8.5e-58 | 190.7 | In-house | 37-280 (293) | alignment | ||
Range on Protein: 38-324
Range on HMM: 37-280/293.0
VNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHL---KTLSGNDYINASYVkvnvPGQSIePGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPL
|.. . .. ...|.|.||| ||.||. .||.| |. ||.|||||.|. ||.. | .|||||| .| |.||.|.. . .|||.| |
vgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyi....pgyns.prefiatqGPlpetvddfWrmvwek...kssiivmltql
VEYNREKCYQYWPRGgvddtvriaskwespgganDMTQFPSDLKIEFVNVHKVKDyYTVTDIKLTPtdplVGPVKTVHHFYFDLWKDMNKPEEVVPIMEL
|| ..|| .|||. . ... |.|...|. ....| ... ..|.. ..|... | | | . ||. .....
vekgkvkCeeYWPad...................eepvlyGdikvtlvaeeeled.wvirelkiek....ekeerkvrqyhftsWpdhgvPektktlldf
CAHSHSL---NSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDfknitersrhsdratEEYTrDlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
. . .. ... .||.|||||||||||||||||.|... . |.| | | || .||..|. .|||..|..||...
vrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaiee...............edyv.d.ifgivaelReeRnllvqtekqYifihqc
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 49-327 | 4.8e-57 | 188.7 | In-house | 8-244 (249) | alignment | ||
Range on Protein: 49-327
Range on HMM: 8-244/249.0
EPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKVNVPGQSiepgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQY
| | .|||..|.||...||.|. |.| .|||||||... .. .||||||. .|.. ||.|.... . ||||.|.|||..||||.||
lpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrr.....fiatqgPlpetvedfwrmlwel...gitvivmLtslvelgrekcaqy
WPRggvDDTVRIaskwespggandmtqfpSDLKIEFVNVHKvKDYYTVTDIKLTPTdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS--
|| .... . |.......|.. ||.|||. ..||.. |.. ||.|... | |.. |. . ...... .. ..
wpl...ggsley.................gdftvtllsvev.kddytvrtleltnl..ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel
-RGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
.|.|..|||||||||||||||.. ... .... .|..| .|||||...||. .|. |.| |...
pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvd.................leeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 52-324 | 4.5e-56 | 185.3 | Pfam-A | 1-232 (235) | alignment | ||
Range on Protein: 52-324
Range on HMM: 1-232/235.0
NDARNRYVNIMPYERNRVHLKTLSG-NDYINASYVkvnvPGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPrgg
| .||| .|.||...||.|| .| .|||||.|| | . |. .||||||. .| ..||.|.... . ||||.| |.| .|||| ||||
nkkknRykdilpydktrvklkgsegpsdYInAnyv....kgyk.ekkkfIatQgPlkstiedFWrmvwqe...kvkvivmltsleekgrekcaqYwp...
vddtvriaskwespgGANDMTQFPSDLKIEFV-NVHKVKDYYTVTDIKLTPTDPLVgPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN-SRGNPI
... .. |.|.| . .... .. ||.....|. .. ..|... . |.| . ||.. ....|. .. . .. .|.
...............eeeeesltygdikvelkekekedekeytlrklelkkkkees.ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpv
IVHCSAGVGRTGTFIALDHLMHDTLDfknitE-RsrhsdrateeytrDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA
.|||||||||||||.||| |.. . | . ||| .||.||..|||. .|. |.|.|
vVhCsaGvgRtgtfvaldilleqlea.....eee.............vdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 52-324 | 4.5e-56 | 185.3 | In-house | 1-232 (235) | alignment | ||
Range on Protein: 52-324
Range on HMM: 1-232/235.0
NDARNRYVNIMPYERNRVHLKTLSG-NDYINASYVkvnvPGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPrgg
| .||| .|.||...||.|| .| .|||||.|| | . |. .||||||. .| ..||.|.... . ||||.| |.| .|||| ||||
nkkknRykdilpydktrvklkgsegpsdYInAnyv....kgyk.ekkkfIatQgPlkstiedFWrmvwqe...kvkvivmltsleekgrekcaqYwp...
vddtvriaskwespgGANDMTQFPSDLKIEFV-NVHKVKDYYTVTDIKLTPTDPLVgPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN-SRGNPI
... .. |.|.| . .... .. ||.....|. .. ..|... . |.| . ||.. ....|. .. . .. .|.
...............eeeeesltygdikvelkekekedekeytlrklelkkkkees.ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpv
IVHCSAGVGRTGTFIALDHLMHDTLDfknitE-RsrhsdrateeytrDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA
.|||||||||||||.||| |.. . | . ||| .||.||..|||. .|. |.|.|
vVhCsaGvgRtgtfvaldilleqlea.....eee.............vdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 43-325 | 7e-55 | 181.7 | In-house | 39-277 (564) | alignment | ||
Range on Protein: 43-325
Range on HMM: 39-277/564.0
SLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNR
. .. .| | |.||| ||..|...|| |... | ||||||... | .. |||||||. .| . ||.|.. . . .|||.| |.| ..
tweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfid....gyr.krkayIAtqgPlaetiedFWRmvweq...nsstiVmltkleEkgk
EKCYQYWPRGGVDDTVRIASKWESPGGANDMTQfpSDLKI---EfvnvhkvkdyytvtdikltptdplVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCA
.|| .||| | .. . |. .|.. ..|. . ...|..|.| | | . ||. ....|
vkchkYWPekgtetygeltVtleeeeeladyei..rtfklkkkk........................ssesreVrqFhFtsWPdhgvpesatslLdlir
HSHSLNSRGN-PIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
....||.... ||.||||||||||||||..| .. .|..|| | | | |.| .||.|| ||||..|. ||..|
kvralnepdagPivVhCSaGVGRTGtfividaml................erikeektvD.iyqyvkalrkqRnamVqteeQYiFiheai
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 51-325 | 5.9e-52 | 171.4 | In-house | 27-264 (274) | alignment | ||
Range on Protein: 51-325
Range on HMM: 27-264/274.0
RNDARNRYVNIMPYERNRVHLKTLSG----NDYINASYVKvnvpGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYW
.. .||| .|.| |. || |.. |. .|||| |.| | . | |.||||| .| ..||.| |.. . ||||.| | | |..|| .|.
gsqtknryktilPnensrvllesessededssyinanyik....GydeeskayvatqGPlpntvadfWrmiyqe...evqvivmltklkeaneqkCavyf
PrggvddtvriaskwespgGAN--DMTQFPSDLKIEFVNVHKVKDyYTVTDIKLTPTDPlvgpVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS-
| |. .... |..|..... . .| |.|. . | . ..|.|... | |.. |... ....|... .. ..
P..................daedyeiserygdveikvekivernd.ysvrklvlkyler....ersvkhywytdWPdhksPddantlldlvleveesree
---RGNPIIVHCSAGVGRTGTFIALDHLMHDTLDfknitersrhsdrateEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYHAA
. |..||||||.|||| ||| . ... . | . |.. .|| .|| .| ||||..|. .|..|
enaklapvvvhCsaGiGrtGcfiaisiavrqlre................eivvdvl.kivcnlrldrGGmvqtseqyelihral
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 51-327 | 5e-49 | 162.0 | In-house | 36-267 (273) | alignment | ||
Range on Protein: 51-327
Range on HMM: 36-267/273.0
RNDARNRYVNIMPYERNRVHLKTLSGndYINASYVKVNVpgqSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRgg
.| ..||| |..||.. ||.|. .| |||||..||.| . |||.||| .| . |||| . . ||.||| .| .. || .|||
enkdknryrnvlPydetrvklgdegg..yinaslikvpv...gkdeyeyiacqGPlPetvkdfwqmvweq...kaeviamvtlekekgkvkchrywPe..
vddtvriaSkwespggANDMTQFPSDLKIEFVNVHKVKDyYTVTDIKLTptDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIV
| .|. .. . |..| ..| | .. ..| ..... | | .. | |. | | | . | . ...... |. .|.. ||.|
........s.......knkklkvsnrlevellkvqkldg.fvvralavk..dsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivv
HCSAGVGRTGTFIALDHLmhdtldfKNITERSRhsdrateeytRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
|||||.||.||.|..| . .. || . ...|| .|| || .||||||..|.|.|. .
hcsaGiGrsGtlitidvv.......lglierdk..........efdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 46-327 | 5.6e-49 | 161.8 | In-house | 48-295 (306) | alignment | ||
Range on Protein: 46-327
Range on HMM: 48-295/306.0
VSIEPRNDARNRYVNIMPYERNRVHL--KTLSGNDYINASYVKVNVPGQSiepGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCY
. |.| .||| ||.|.. .|| | . ..|.|||||.|.| .|.|.. .|||||| ..| .||.| . . . ||||.| || ..|||.
egakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsd...ksyiatqgclettvsdFWrmvwqe...nsrvivmttkevErgkekCa
QYWPRGGVDDT---VRIASKWESpggandmtqfpsdlkiefvnvhkVKDYYTVTDIKLTPTDPlVGPVKTVHHFYFDLWKDMNKPEEVVPIMELC----A
.||| ... ... . |. ...|.. ..... .. . ..|... | | | . |.. .... .
rYWPdeeekeeyGkisvtnvsek.......................sladYilRelsvskkkk.kkeerevfqyhfksWPdhgvpkdpgavLdfledvnr
HSHSLN-SRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfKNITERSRhsdrateEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
....|. .. ||.||||||.||||||| .| |. |.|... .. | |...| ..|.|| .|||..|. |.|.| |.
kqeeleeaeagpivvhCsaGiGRtGtfiviDill......kliekkgl.......dadid.iqklvksvreqrsglvqteqqykfvykaikk
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 37-324 | 2.8e-46 | 152.9 | In-house | 32-282 (563) | alignment | ||
Range on Protein: 37-324
Range on HMM: 32-282/563.0
TVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---N-DYINASYVKVNVPGQSiepgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVT
|... | .| | .|||.||..|.| ||.|. |.| . |||||.|.. .. .|||||| ..| | ||.| . . .|||.|
tiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkska.....fiatqgplkdtfddFWrmiWeq...nvaiivmit
PLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFpsdlkiefvnvhkvkdYYTVTDIKLTPTDPlVGPVKTVHHFYFDLWKDMNKPEEVVPIM
||| .|.|| .|||. .. . . . .. |. .. ..|| .. .|.| .. . | |.. || .| .
nlvergrrkcdvYWPkdesetygalqvtlieeevlalytvr................tlviknlklkkkkq.cdteklvrqyhytkWPdhgvPehslpvL
ELCAHSHSLNSR-GNPIIVHCSAGVGRTGTFIALDHLMHDtLDFKNITErsrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
.| | . ||.||||||||||||.|.|| |... . .|. . . ... ..|.|| .|||..|..|.. |
ifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkq.iqqenavn................vfgflkhiraqRnflvqteEqYiflhda
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 44-330 | 3e-46 | 153.0 | In-house | 48-292 (298) | alignment | ||
Range on Protein: 44-330
Range on HMM: 48-292/298.0
LGVSIEPRNDARNRYVNIMPYERNRVHLKTL---SGNDYINASYVKvNVPGQSiepgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNRE
|. .|.| .||| .|.... || |.. ||||||... . |.. .||||.| .| .||.| .. | .|||.|.|.| ..
kevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflh.aykgrn....afiatqaPltetvedFWrmvtee...digtiVmltnleeldkt
KCYQYWPRGGVD--DTVRIaskwespggandmtqfpsdlkiefvNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHS
|. .||| | . ..... .... ... .. ||. .. . ..|... | | | ||. ...| ..
kyhkywPdegketygeitv.........................sllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkv
HSLNSRGN--PIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA-KYLNS
. ... |.||.|||||||.|||||.| .. .|. .| . | . |.| || .|...|||..|. |||.| ..|.|
rasqqqagnkpvivqCsaGvgRsGtfiaidsvl................ervkkeqvvD.vfqvvkvlRkkrpgavqteeqYvfiyeavlealds
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 51-326 | 4.5e-46 | 152.0 | In-house | 19-261 (270) | alignment | ||
Range on Protein: 51-326
Range on HMM: 19-261/270.0
RNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKvnvpGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNREKCYQYWP
|. . ||| .|.| . || |..|. . |||| ||. | . |. .|||..||. | .||.| ... |||.|.|.| .|.|| .|||
rgkklnRyadiLPsPatRvrleeleedsataYinAnyvr....GfdgekkkYiaamgPlpttlksfwrmiweekv...taivmttgleEkgrkkCerYWp
RggvddtvriaskweSPGGANDMtqfpSDLKIEFVNVHKVK-DYYTVTDIKLTpTDplvGPVKTVHHFYFDLWKDMNK---------PEEVVPIMELCAH
.|. .. .| ||. ......| . | .| ..|. .. | . . ||.. | | ..... ... .
a..............epkekvkl....edgkikvlalseekeegyiltrlrle.ek...geerrlvHfwyntWpdhgvpreedsslstdqllkmlravrr
SHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHdTLDfkniteRSRHSDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
|.. ....|..||||||||||||.||||. .. .|. .... | . .|. .|| .||..||. .|. |.|.|
sekeldkaePllvHcsaGvgRtGtlialDiavr.lLe......etkkvd..........vlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 42-326 | 1.1e-45 | 150.8 | In-house | 30-274 (290) | alignment | ||
Range on Protein: 42-326
Range on HMM: 30-274/290.0
WSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKVnvPGqsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYN
.| .. ...| ..||| .|.||. .||.|.. ... |||||...| . .. |||.||| || |.||.| .. . ..||. .|| .
ysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikg..ve...gkleyiaaqgPLpktlddfWrmiwek...nveivvmaCrevelg
REKCYQYWPRGGvddtvriaskwespggaNDMTQFpSDLKIEFVNVHKVKDYYTVTDIKLTPTdplvGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHS
. || .||| | .. ..| ...... . ..|.| ... .|.. . ..|. | . | | . |. . ...|| ..
kkkCerYWpeeg.................eeelef.gefevtleeekavdddflirtLkveaq....kesrkvyqfhYtaWPDhgvPssaksllelielv
HSLNS-RGNPIIVHCSAGVGRTGTFIALDHLMhDTLDFKNITERSRhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
..|.. .|..|||||||||||| ||.|. . | ..|.|. . ..||.|| || .||||.|. ..|.|
relqesedaPlvvhCsaGvGrtGtiiaidyvr.ellkaekipeeld.............vfdlvlelrkqraalvqtkeqyelvykava
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 49-325 | 4.6e-45 | 148.9 | In-house | 55-291 (330) | alignment | ||
Range on Protein: 49-325
Range on HMM: 55-291/330.0
EPRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQY
. | .||.|||.||. .||.| ...|. ||||||... | | ..||.||| ..| . ||.| . . |||.| | | ..|||.||
keenkeknrvvnilPydfsrvilsvkeGveesdyinasfid....Gyk.ekdkfiaaqGPkeetvedfwrmiweq...ksativmltelkerkeekcaqy
WPRGGVddtvriaskWESpGgandmtqfpsDLKIEFVNVHKVKDyYTVTDIKLT--PTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS
|| |. . | ....| .. ..| ||| .. .. | ... |. |.| | |. | | . ...| .. ..||
wPdeGl.........vty.G..........nirvevedetvlvd.ytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnq
-RGNPIIVHCSAGVGRTGTFIALDHLMHDTldfknitersrHSDRATEEYtrdlieQIVLQLRSQRMKMVQTKDQFLFIYHAA
..||.||||||||||||||.|| ... ...| . . ..| .|| || .||||. |. |||..
qsagpivvhcsaGvGrtGtfivldavlerv...........kaerkvdvf......efvkrlrlqrpqmvqtdeqyefiykvl
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 47-326 | 4.3e-44 | 145.7 | In-house | 36-273 (281) | alignment | ||
Range on Protein: 47-326
Range on HMM: 36-273/281.0
SIEPRNDARNRYVNIMPYERNRVHL---KTLSGNDYINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCY
| .. | .|||.||. |. ||.. .. . .|||||..|. | . .. ||||||| .. ..|||| . . . .||||| .| .. ||.
skadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvp....gyk.gekeyiatqgPvPaslvafWqmvweq...kvsaivmvtreieagklkCh
QYWPRGGVddtvriaskwespggandmTQFPSDLKIEFVNVHKVKDyYTVTDIKLTPTDplvGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS
.||| . . .|....... .. . | .||. .. |. ..|... . | | |.. ..| . ..|..
rYWPddns...................elkygdvtvkstaeeekat.yierkfkleres...getreveqlaytaWPdhGvPattkellefrkevlklte
RGN--PIIVHCSAGVGRTGTFIALDHLMHDTldfkniTERSRHSDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
. . |...|||||||||||.|||| |.. ... .. | ....| .|| .|. |||| |. |.|.| .
kktkaplvihCsaGvGrtGtyialDrlvkav......eaeleeld..........vkavvaelrkernlmvqtvvqyefvykavl
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 42-324 | 6.5e-44 | 144.8 | In-house | 22-266 (290) | alignment | ||
Range on Protein: 42-324
Range on HMM: 22-266/290.0
WSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSgNDYINASYVKVNVPGQSiepgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREK
.. .. .|.| ..||| .. ||. |..|. . ||||||| |... .| || |||| .| | |||| ... . .||. .|| .. |
fptreaklpenrnlnryrdvspydhsriklerad.ndyinaslveleeakrs.....yiltqGPlpntvdhfWqmvWeq...kskavvmlnkvvekeqik
CYQYWPRGGVddtvriaskwespggANDMTQFPSDLKIEFVNVhKVKDYYTVTDIKLTptDPLVGPVKTVHHFYFDLWKDMNKPEE---VVPIMELCAHS
|.||||.| . .. . ||..... ..|.|||| ..|. . ... ||.. | |. || . . . .|
caqywPqgee...............ekellledtklkvklise.erksyytvrllele..nlktqetreilhfhyttwpdfgvpespaaflkflfkvres
HSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDtldfknITERsrhSDRAT-EeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
||.| | ..|||||.||.|||. .| .. | .. | .. . |.. .|.||..|. ..||.||. | | |
GslssdvGpavihcsaGiGrsGtfclvdtclvl......iekk...ddlssvd......ikkvllelrkyrlGliqtadqlrfsyla
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 46-324 | 1.1e-43 | 144.2 | In-house | 35-270 (280) | alignment | ||
Range on Protein: 46-324
Range on HMM: 35-270/280.0
VSIEPRNDARNRYVNIMPYERNRVHLKTLSGnDYINASYVKVNVPGQSIEPgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQY
.. |.| ..||| .|.||. ||.|| . |||||.||....|.... ||||||| .|| .|||| ... . .|||.| ||| | ||.||
aarkpenlsknryrdilpydatrvklkeset.dyinanyvnmeipstglvn.ryiatqGPlaktatdfWqmvweq...ksslivmlttlverGrvkChqy
WPRggVDdtvriaskwespgganDMTQFPsDLKIEFVNVhKVKDYYTVTDIKLTPTDplVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN-SR
||. . | ... ..... . . . | . .. |. .. ...... . | | . |.. ..|. . ..| ..
WPe..te................deleyg.efsvkceke.detksyvlrelvlkdke..tkeerkilqlqylaWpdhgvPddsadflefvervrklrsgk
GNPIIVHCSAGVGRTGTFIALDHLMHdtldfknITERsrhsdrATEEYTRDlieqIVLQLRSQRMKMVQTKDQFLFIYHA
.|..||||||.|||| .|.|. .. ..|. | . | | || ..| ||. .|||..|. |. .|
eePvvvhCsaGigrtGvlilletala.......liea......aepvypld....ivrtmrdqramlvqtasqykfvCea
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 46-324 | 5.3e-42 | 139.0 | In-house | 42-281 (307) | alignment | ||
Range on Protein: 46-324
Range on HMM: 42-281/307.0
VSIEPRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKVNVpgqsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKC
|| . | .||| .|......|| ||.. |. ||||||..| | .|| |.| | . ||.| . .|||.. | |.||.||
vsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgyk.....ekkkfiaaqdPveatigDfWRmiaeq...evtlivmlsnlteknrkkc
YQYWPRGgvddtvriaskwespgganDMTQFPsDLKIEFVNVHKVKDyYTVTDIKLTPTD---PLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSH
.||| | .|. |. ...|. .| .| |. ..... .. . | . | . . |||.. || ...| . .
akYWpie...................devqyg.dilvklvseekhsd.yiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvr
SLNSR-GNPIIVHCSAGVGRTGTFIALDHLMHdtldfkniteRSRHSDRATeeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
.|.. ||.|||||||||.|.|.||| |.. . . |.. | ..| .||||| .|| .|. |.|.|
elyklnrsPivvhCsaGvgrsgifvaldsllq..........qlkaedkvd.......ifetvkdLrsqRnllvqsleqYvflyra
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 45-324 | 7.3e-42 | 138.2 | In-house | 36-275 (288) | alignment | ||
Range on Protein: 45-324
Range on HMM: 36-275/288.0
GVSIEPRNDARNRYVNIMPYERNRVHLKtLSGNDYINASYVKVNVPGQsiePgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
..| .. .||. .|.||..|||.|. | .||||||.|| .|| | .||||.| ..| ||.| |.. ||||.. | ...|. .
siaiaklyseknrsrdilPyDhnRvklr.gskDDYinAsfvkdlspgc...P.dfiatqaPlqstlnDFWlmvyeq...kssviVmllskeelgkpkvdr
YWPRGgVDDTVRIASkwespggandmtqfpsdLKIEFVNVHKVkDYYTVTDIKLTPTDPlvGPVKTVHHFYFDLWKDMNK---PEEVVPIMELCAHSHSL
||| ..||. |.. .|.. ... ..||. |. ||.| | . | .. ||... ... ....
YwPed.kgetvkfgd.................lsvtlksvret.ethvervlkletlda..davksvshlqltsWpelGvPasPetllqfldevesayea
NSR--GNPIIVHCSAGVGRTGTFIALDHLMHDTlDFKNITErsrhsdrateeytrdLIEQIVLQLRSQRMKMVQTKDQFLFIYHA
. | |..|||||||||||.| . .... . .|. | |.| .|| || |||.|.|. | |.|
vqrksktPlvvhCsaGvgRtgvfalvyaavrel.ekgngll...............diiqvvsrlreqRrfmvqekeqlkfsyea
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 43-325 | 3.7e-41 | 136.2 | In-house | 39-279 (319) | alignment | ||
Range on Protein: 43-325
Range on HMM: 39-279/319.0
SLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKVNVpgqsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNR
.. . ...| .||| ||..|.| || |..| | ||||||.. | .||||.| .| . ||.| ... . ..||.| ||| .
tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyq.....erekfiatqaPlentiedfWrmvWee...essivvmltklveklk
EKCYQYWPRGgvddtvriasKWESPGgandmtqfpsDLKIEFVNVHKVKDyYTVTDIKLTPTDPLVGPvKTVHHFYFDLWKDMNKPEEVVPIMELCAHSH
|. .|||. ..|. | | .. . .. .| | . ..|| . | ..| ||.. | | . ||. ...| . .
vklkkywpee..........nfeeyG..........rlivtleeeeeled.yiirklklnkkssevet.RevkhfqyteWpdhdvPekatslldllkrir
SLNSR--GNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYHAA
.. ||.||||||||||||||.|| . .| || . |. ..| .|| || |||...|. |||.|
ksrektqsgPivvhCsaGvGRtGtfivldaml................ervkeegvlDvf.stvsrlRtqRnimvqrpeqYkfiyeal
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 39-324 | 1.5e-40 | 133.9 | In-house | 33-278 (290) | alignment | ||
Range on Protein: 39-324
Range on HMM: 33-278/290.0
NSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGN-----DYINASYVKvnvpgQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTP
.| . | . . | .||. ||..|. ||. |. .||. .||||.|.| . | |||||||. .| .||.. ... . .|||.|
esehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyik.....gykekkqyiatqgpvsntlvdFWkliwqe...kvtiivmltn
LVEYNREKCYQYWPRGGVDDTVRIASKWespggandmtqfpsdlkiefvNVHKVKDYYTVTDIKLTPTDPLvGPVKTVHHFYFDLWKDMNKPEEVVPIME
.| ...||.|||| .... . | . .. ..|. . .... .. |. ..|... . |.. | .. |.
iieegkvkCqqYWpdsdtkaygefsikl.....................lneetlneyierklevknknsa.gakqsvtqyqitnwdstgkvtnpqtill
LCAHSHS--LNSRGNPIIVHCSAGVGRTGTFIALDHlmhdTLdfknitersrhsDRATEEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYHA
. .. . ..|.||||..|||...|.|.. |. ... | |.. |.. ..|.|....|||..|. .|..
vieemyktqrkrgntsivvHCSdtvgrsavfcaaat....ti............nkcktegvidvf.qvlksqRiqkpgsvqtvqqyqgifqi
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 52-327 | 2.1e-40 | 133.6 | In-house | 1-169 (182) | alignment | ||
Range on Protein: 52-327
Range on HMM: 1-169/182.0
NDARNRYVNIMPYERNRvhlktlsGNDYINASYVKVNVPGQSiepgyYIATQGPTRKTWDQFWQMCYHNcpldNI-VIVMVTplveynrekCYQYWPrgg
| .|||..|.||...| ..|||||... . |.. .||||||. .|. .|..| ... .| .||..| ...|||
nldknrysdilpydhsr.......dldyInanlylgslpatr.....fiatqgpllstvadflrmlkel....gittivnlt.........eelywp...
vddtvriaskwespggandmtQ-FpsdlkiefvnvhkvkdyytvtdikltptdplvgpVKTVHHFYFDLWKDMNKPEevvpIMELCAHSHSLNSRGNPII
. . ........ | |.. |. . ||.. . ...|.|..
.....................ell..................................erlgiqylylpwpDhgvpd....ldelldfieevleeggpvl
VHCSAGVGRTGTFIALDHLMHDTLDfknitersrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
||||||||||||..|.. ... .. .|..| ..||.|..||.| .|. |.. |. .
VHCsaGvgRtgtlvaaylmkklgvs......................leeavklvrsrRpgmvitpnqyfflqlalle
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 50-324 | 3.8e-40 | 133.1 | In-house | 59-286 (319) | alignment | ||
Range on Protein: 50-324
Range on HMM: 59-286/319.0
PRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKvnvpG-QsiEPGYYIATQGPTRKTWDQFWQMCYH-NCpldnIVIVMVTplveynREKCYQ
..| .||..||.....|.| |. | | ||||||.|. | | . |||.||| | . ||.| . || ||..| ..|| |
dqnkdknriinilafdknvvklerliGeefsdyinasfvt....Gyq..rkdkyiaaqGPldntladfWrmiweync....stivllt......kdkcsq
YWPRGGVDDTVRIASKWESPGGANDmtqfpsdlkiefvnvhkvkdyYTVTDIKLTPtDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAH---SHSL
||| .| | | .| ... |.| ||.|. | .. .. |.| | |. .|. ...| | . .|
ywplkivikeerfkvkvdsveetae.....................yvvrdielse.dgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltsk
NSRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
. ..|.|||||||||||..|.|| |. || || | . ..| .|| || ..|| |. ||| |
enhranivvhcsaGvGrtGvyivldvll................drmkeekqvd.vynfvrdlrqqrntlvqdlvqykfiysa
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 74-327 | 9.6e-40 | 132.3 | In-house | 1-223 (272) | alignment | ||
Range on Protein: 74-327
Range on HMM: 1-223/272.0
LSGNDYINASYVKVNvpGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPldniVIVMVTPLVEYNREKCYQYWprggvddtVRIASKWESPGGANDMTQF
|. ..||||..|. . |. . ||......||.. |...||... ... .||......|..|.||..|| | . . . ..| .
lplsgyiNardvggy..grvvkpgrlyrsggplpltaadfwrlkelgik....tivdLrseeErgrlkcdryw........pgirylhlpilddsaptil
PSDLKIEFVNVHkVKDYYTVTDIKLTPTDPLVGPvKTVHHFYFDLWKDMNKP-EEVVPIMELCAHshslnsrGNPIIVHCSAGVGRTGTFIALDHLMhDT
.| . .. .. ....|... . || . . . .|.|... | |.. | |... ..||... |.|..||||||..||||..||..|.
ygalrvtllsee.llldyilrellltlllsagea.revmhlhytdwpdhgvpqeallellellld.......ggpvlvHCsaGkdRTGtvvalllll.lg
LDFKNITERSRHSDRAteeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
.. | . . .. . .|..| .||.||...||| .|.||.|.|..
vsletivddYlltnly........leeaveelraqrpgavqteeqylflyealle
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 50-324 | 1.8e-39 | 131.0 | In-house | 23-250 (284) | alignment | ||
Range on Protein: 50-324
Range on HMM: 23-250/284.0
PRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKvnvpG-QsiEPGYYIATQGPTRKTWDQFWQMCYH-NCpldnIVIVMVTplveynREKCYQ
..| .||...|.....|.| |. | | ||||||... | | . ||||||| | . ||.| . || ||..| ..|| |
dqnkdknrighilafdknvvklerliGeefsdyinasfit....Gyq..rkdkyiatqGPldntladfWrmiweync....stivllt......kdkcsq
YWPRGGVDDTVRIASKWESPGGANDmtqfpsdlkiefvnvhkvkdyYTVTDIKLTPTDpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAH---SHSL
||| .| | | .| ... |.| ||.|. ..... |.| | |. .|. ...| | . .|
ywplkivikeerfkvkvdsveesee.....................yvvrdielsedg.kekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltsk
NSRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
. ..|.|||||||||||..|.|| |. || || | . ..| .|| || ..|| |. ||| |
enhranivvhcsagvgrtgvyivldvll................drmkeekqvd.vynfvrdlrqqrntlvqdlvqykfiysa
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 44-325 | 1.5e-38 | 127.7 | In-house | 38-279 (305) | alignment | ||
Range on Protein: 44-325
Range on HMM: 38-279/305.0
LGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGND---YINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNRE
. | . | |.||...|.... .|..|.. . .| |||||||. | . . ||..||| ..| ..||.. .. . .|||.| ||| ...
idvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvd....gyk.rkkkyivaqgPlkntvadfWrliveekv...stivmltklveggkd
KCYQYWPrggvddtvriaskwESpggANDMTQFpSDLKIEFVNVHKVKDYyTVTDIKLTPTDPlVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSH-
||.|||| || .. ..| ....| . ....|| . ..|.. | .|| .. . | | |.. ...| . .
kCrqYWp..............es...ktekkef.gefsvelksektasdy.ieRklkisiede.dkesrtvlqyqltdWPdhGvpqfatsllslikrvqk
-SLNSRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYHAA
...| |..|||||||||||.|||.| . .|. .| . |. ... ||||.|||||||.||. |.. |
dqkkdkgvpllVhCsagvgRtGvfiavdial................erlkkEevvdvf.evlkqlRskrmkmvqtldqYvflhdal
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 14-325 | 2.3e-38 | 126.8 | In-house | 8-273 (314) | alignment | ||
Range on Protein: 14-325
Range on HMM: 8-273/314.0
DLLGKFKFIQNQEDGRLREATNGTVNSrWSlgVSIEPRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVkvnvpGQSIEPGYYIATQGPTRKTW
||| . . .. | ..| . .. | .. . | ..||. .|..|.| || |.|. |. |||||... | .|.|||| ..|
dllqsiallkraegygfkeeyeslfeg.wd..aakkdenreknrsgdilaydrsrvflitidgdpssdyinaali.....dsykrpaafivtqgPlqetv
DQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPrggvddtvriaskwespgganDMTQFPSDLKIEFVNVHKVKDYYTVTdIKLTPTDPLVGPVKT
||.. |.. . |||.| ||| | ||..||| . |. |.|.|.|... ... . . ... . . ...
kdfWrlvyde...ncasivmltelvevgrvkClkyWP.....................edtevygdikvelvetellaelvvri.frveklargqeeire
VHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRG-NPIIVHCSAGVGRTGTFIALDHLMhDTLDFKNITErsrhsdrateeytrdlIEQIVLQLRSQRM
|..| | | | . | . ...| .. .. . . .|.|||||| ||||||||.| .. | .. ... . . ..| .|||...
vrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl.dmieregvvd................vfnavktlrsrkv
KMVQTKDQFLFIYHAA
||.|..|. ||| ..
nmveteeqykfiydvi
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 47-329 | 1.1e-37 | 124.6 | In-house | 4-243 (250) | alignment | ||
Range on Protein: 47-329
Range on HMM: 4-243/250.0
SIEPRNDARNRYVNIMPYERNRVHLKTLS---GNDYINASYVKVNVpgqsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREkCY
. .|.| .||| .|.... || |.. . ||||||.... | .|||||| .| .||.| ... . .|||.| |.| ... .
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyd.....erkafiatqgPlqatiedfWrmvlee...ksgtivmLtnLkesekt.yh
QYWPrggVDDTvriaSKWespGgandmtqfpsDLKIEFVNVHKVKDyYTVTDIKLTPTDPlvGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS
|||| |. . |. | |.... . .. | ||.. .||. . ..| .. | | | ||. ..|| . .. .
qywP...veka....eky...G..........dvtvsllskeefad.ytkrklklskakk..aderivrqlhfvvWPdkgvPevatavLellkkvqasqq
R--GNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA-KYLN
. .|.||.|||||||.|.|||.| .. .|. .| . | . ... .|| .|...|....|. |.|... |.|.
qagnaPvivqCsaGvgrsGafiaidavl................erlkkekvvd.vfkvikvlrkdrphavesleqyvfvyeiilkald
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 47-327 | 7.2e-37 | 122.0 | In-house | 44-295 (300) | alignment | ||
Range on Protein: 47-327
Range on HMM: 44-295/300.0
SIEPRNDARNRYVNIMPYERNRVHLKTLSG--NDYINASYVKVNVPGQSIEpgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
. | | .||. ...||| |||.|.. ..||||| .|| | |.. . ||..||| ..| .|||| . . . .|||.| | .||...
aklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkers...yivaqgPleltvqdfWqmvWeq...gvqlivmlteeeedgkeksfk
YWPRGGVDDTvRIaskwespgganDMTQFpsDLKIEFVNvhKVKdYYTVtdIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIME-------LCAH
|.|. . .. . .| . .|.. . . .. ..|. . . .||.|. . | | . ||.| . .. .. .
yfPkleskkk.tv...........efgkf..kvttkfse..dsd.svit..tglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrk
SHSLN---SRGNPIIVHCSAGVGRTGTFIALDhLMHDTLDFKNITErsrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA-KY
..| . .. |..||||||||||| | | |. ||. . . |.... .|| ||| .||| |. |.|.. ||
tnseveskeskPPvlvhCsaGvGrtGvlilsd.lliatlehneeid................ikkvlarLreqrmllvqtlaqYkfvYkvliky
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 50-325 | 1.2e-36 | 121.0 | In-house | 31-262 (283) | alignment | ||
Range on Protein: 50-325
Range on HMM: 31-262/283.0
PRNDARNRYVNIMPYERNRVHLKTLSGnDYINASYVKVNVPGQsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRG
.|. ||. .|.|....||.||..| |||||... |. . . ||..|.| ..| ||.| ... . |||.|.| | .|.|| ||||.
denkrknrnqeivpadqwrvelksesr.dyinavfipvsksyk..qdkkyiiaqsPldrtvvdfWkmvfde...kitaivmltklqedlrikCsqyWPkr
GVDDTVRIASKWESPGGANDMTQFPSDLKIEfvnvhkvkdyytvtdikltptdP-----LVgpvktVHHFYFDLWKDMNKPEEVVPIMEL-CAHSHSLNS
| | . . . | ... |. . |. . |. .. | .... . .. . | .|
GsedyGeftvtlrkettsnsfiikelllrvn......................ssakstll.....lahyqvidWleygeqaiinslvkfnkvislqtes
RGNPIIVHCSAGVGRTGTFIALDHLMHDTLdfknitersrhsdratEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
. ||.||||.|.|||..|||. ..| | | | . ..| .| ||| .|||.||. ......
kkgPivvhCstgiGrtavfiaasasvkdal................tesvvd.vfavvkimreqrmmavqtldqyklvhelv
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 76-324 | 2.9e-36 | 120.1 | In-house | 1-165 (174) | alignment | ||
Range on Protein: 76-324
Range on HMM: 1-165/174.0
GNDYINASYVKVNVPGQsiepgYYIATQGPTRktwdqFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRggvddtvriaskwespggandmtqfps
|.||||||...... ..||.|||.. ||.|.... . ..||.....| ...||..|||.
gsdyinaspldlsyitp.....rliagqgpla.....fwemlkel...gittvvmlleekelglykcinywpe...........................
dlkiefvnvhkvkdyytvtdikltptdPLVGPVKTVHHFYFDLWKDMNKPEEVVpIMELCAHSHSLNSR--GNPIIVHCSAGVGRTGTFIALDHLMHDTL
.......... | |.. |. . . |.. .. |. |.|..||||||||||||..|.. ... |
...........................lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll
-DFKNItersrhsdrateeytrdliEQIVLQLRSQRMKMVQTKDQFLFIYHA
.. .. ..| .||.||..|||| .|. |.|
eslvda...................ldlvrelRlqrpgmvqtpsQyrflyyf
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 49-325 | 1.6e-34 | 114.4 | In-house | 47-280 (297) | alignment | ||
Range on Protein: 49-325
Range on HMM: 47-280/297.0
EPR-NDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKVNVPgqsiepgYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNReKCYQ
| . | ..|| ||.||...||.|. . . ||.|||.||.| .|.|| | . | . ||.| ... . .|||.. . | .. || .
ekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh.......rlittqmPmkatvadfWamvldeqv...stivmlnddnerdk.kcar
YWPRGGVDDtvriaskwespggandmtqFpSDLKIEFVNVHKVKDYYTvTDIKLTPTDPLVGpvKTVHHFYFDLWKDMNKPE-----EVVPIMELCAHSH
||. || | |. .. |.. . . ....| .. . . |. . | | | . .. .. ... ...
yWsdkgvtt...................f.GdvsvvllsvsereGfik.relevtkgkakar..rvvkqyqfveWPdkaverkdsassllklisevrkdf
SLNSRGnPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNItersrhsDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
| |. | |..|||.||||||| ....| . . . |.. | | ..| .|| .|...||||.|. |.| |
sqnaeg.PllvhclaGvGrtgvlltidsvvaeakrekev.......d..........ifglvkklrqerpylvqtkeqykfvyvav
|
|||||||||
| PTPc_DSPc_SM00012 | 210-326 | 3.6e-34 | 112.5 | In-house | 1-104 (105) | alignment | |||
Range on Protein: 210-326
Range on HMM: 1-104/105.0
TVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSR---GNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKnitersrhsdrateeyTRDLIEQIVLQLRS
||.|... |.|...|||. .|.||... .. .. ..|..|||||||||||||.||| |... . . ... |.||| .||.
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket................kevdifqivkelrk
QRMKMVQTKDQFLFIYHAAK
||..||||..|.||.|.| .
qRpgmvqteeqylflyrall
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 44-324 | 4.2e-34 | 113.1 | In-house | 40-283 (325) | alignment | ||
Range on Protein: 44-324
Range on HMM: 40-283/325.0
LGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKvnvpgQSIEPGYYIATQGPTRKTWDQFWQMC-YHNCPldnivIVMVTPLVEYNR
|. | | |.||. |.......|| |.|. |||||||.. . .. ..|.| | .| . .|.. .|. .|.|. .. .
kkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylr.....ddkkkdvflaaqaPltatindlWrlvldWrcs.....vvvvlneldlgk
EKCYQYWPRggvddtvRIaskwespGganDMTQFpSDLKIEFVNVHKVKDYY-TVTDIKltptDPLVGPVKTVHHFYFDLWKDM---NKPEEVVPIMELC
..| .|||. .. | . .| |..... . .. || | |.| .. | ..|. | . |.|| ..| ...|..|
drcavywpk.......em.......g...ksktf.Gglevklrtieeisdyvhrvldvk....qvkkGetrsvkqfqlqswddmGvqkrpatlisilqlv
AHSHSL---NSRG-NPIIVHCSAGVGRTGTFIALDHLMHdtldfKNITErSRHsDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
. . |... ||.|||||||||||.||.| .. | |.| || | | . | .|| .| .||.| ||. .||.|
kavservtantkastpilvhcsaGvGrtGvfislysala.....kviee.srv.d..........ifgfvkklrkdrpsmvetvdqyiliyea
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 46-325 | 5.4e-34 | 112.2 | In-house | 37-272 (515) | alignment | ||
Range on Protein: 46-325
Range on HMM: 37-272/515.0
VSIEPRNDARNRYVNIMPYERNRVHLKTLS---GNDYINASYVKvnvpgqSIEP-GYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNREK
|. | | .||| ||.||...|| |. . .||.||||.. |.. |||.||| . . | ||.. ... . |.||| | | .. |
vaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyip......sfdndkayiasqgPnkasvddfWrlvlqenv...ttiamvtklkegdkik
CYQYWPrggvddtvriaskwESPGganDMTQFPsDLKIEFVNVHKVKDYyTVTDIKLTPTDPlvgpVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSL
| .||| . || | .| .|.| | .. . . .... | ..|| | | | | |.. .. | .
cgkyWP..............dkpg...dsvkfG.sikvelvsleactgg.ikrkltvlkgdd....srtvtqfhfteWPdkGvpkhtssllklikevkad
-NSRGNPIIVHCSAGVGRTGTFIALDHLMHDTldfknitERSRHSDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
. |.|.|||||||||| .|..| . . . .| | . ..| ..| .|...|||..|. ||| |
hgqythpliihcsaGvGrtGvvisidsvvaha.......kttrmvd..........vfnfvtnirqkrpylvqtqeqyafiygav
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 46-325 | 9.5e-34 | 111.6 | In-house | 38-273 (315) | alignment | ||
Range on Protein: 46-325
Range on HMM: 38-273/315.0
VSIEPRNDARNRYVNIMPYERNRVHL---KTLSGNDYINASYVKvnvpgqSIEP-GYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNREK
|. |. | .||| ||.|....|| | .|||||||.| |.. |||.||| . . | ||.| ... . ||||| . | .. |
varetinfkknryknilPldsarvkleviddsPdsdyinasyik......svdddkayiasqgPlkasvddfwrmvlqekv...ttivmvtkkqegdkik
CYQYWPRggvddtvRiasKwespggaNDMTQFPSdLKIEFVNVHKVKDYYTvtdIKLTPTDplVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSL
| |||| | | | ..| | .|.| .... | . ||. . .|| | | | | .... ...| .
crqywPd.......r...k.......adsvefGs.ikvellsleadtdgva...rklvtrk..seesrtvtqfqftewPdkGvdkqtssllklikevkad
-NSRGNPIIVHCSAGVGRTGTFIALDHLMHDtldfknItERSRHSDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
... ...||||||||||| .|..|. . . | .|.| | . ..| .||..|...|||.... ||| |
ngkkefsllvhcsaGvGrtGvvisidevvaq......i.krtrsvd..........vfnfvknlrakrpylvqteeeyafiydav
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 48-324 | 1.7e-33 | 111.0 | In-house | 38-285 (297) | alignment | ||
Range on Protein: 48-324
Range on HMM: 38-285/297.0
IEPRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
. | .||| ... |.. ||.|...... |||||..| | .. .|||||| .|| . ||.| . . . .||||.| .|| | || |
klranleknrytdvlcydetrvvlakvdedeasdyinanfvd....Gyk.qkkafiatqGplkktvsdfWrmvWeq...evlvivmttrvvergrlkcgq
YWPRGgvddtvriaskwespggANDMTQFpSDLKIEFVNVHKVKDYyTVTDIKLTPTDplVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCA--------
||| . .....| .||... |.|.. .|| .|. .... .. . ..| || | | | |.. ....
yWple.................eessaef.gdlsvsnveveeeedy.kvrvleiknvk..teesrkvthfqflsWPdyGvPssaaslldvlekvrekqal
------HSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfkniterSRHSDRATEEytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHA
... . .| ||.||||||.|||||||.|| . || . .| . . . | .||.|| ..|| .|. | | |
avkelgdewkghpsgPPivvhcsaGiGrtGtfitldicl............srleevgtvd.....vvetvkllrtqrafsiqtpeqyefcyla
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 76-328 | 1.5e-32 | 108.2 | In-house | 11-172 (176) | alignment | ||
Range on Protein: 76-328
Range on HMM: 11-172/176.0
GNDYINASYVKVNvpgqsiepgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR----GGvddtvriaskwespggandmt
. |||||... . ..||||||...| .|..| ... . ..|..| .||..| ||..|||. |
dldyinanlilgs.........rpiatqgplprtladflemlkel...gitavvnlteevelgrlkcpnywpeleklgi.....................
qfpsdlkiefvnvhkvkdyytvtdikltptdplvgpvktvhHFYFDLWKDMNKPEEvVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLmhd
.... | |.. |. ..||.. .. ..|.|..||||||.|||||..|.. |
.........................................qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayll...
tldfknitersrhsdrateE--YTRDLiEQIVLQLRSQRM-KMVQTKDQFLFIYHAAKYL
| . .. |... ..|.||. ..||| .| |.|.....|
...................elekglsv.eealalvreqRplgavqtpeQyrflyefelll
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 76-328 | 1.8e-31 | 104.6 | In-house | 4-160 (172) | alignment | ||
Range on Protein: 76-328
Range on HMM: 4-160/172.0
GNDYINASYVKVNVpgqsiEPGYYIATQGPTRKTWDQFWQMCYHNCPLDnivIVMVTPLveynrekcyqywprggvddtvriaskwespggandmtqfps
|.|||||||..... | .||||||.| |...||.|.... ||..|.|
gsdyinasyldlyy.....ipdrfiatqgplrntladfwrmlkelgith...ivnltel.........................................
dlkiefvnvhkvkdyytvtdikltpTDPLVGPVKTVHHFYFDLWKDMNKPeEVVPIMELCAHSHS--LNSRGNPIIVHCSAGVGRTGTFIALDHLMhdtL
. . . .... .... | |.. | ..|.. .. ..|.|.|..||||||||||||..|.. .. |
.........................lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml...l
DFknitersrhsdrateeytrdLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
.. .|..| ..|..|...||...| |.|. .|.|
gl....................sleeavalvrekRpgavqnpsqyrflyyfekll
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 34-327 | 3.7e-31 | 104.4 | In-house | 28-278 (314) | alignment | ||
Range on Protein: 34-327
Range on HMM: 28-278/314.0
TNGTVNSRWSLGVSIEPRNDARNRYVNIMPYErNRVHLKTL--SGNDYINASYVKVNvpgqsiepGYYIATQGPTRKTWDQF----------WQMCYHNc
....| ..... |. ..| .||| .|.|.. |||.|..| || ||||||||. .||||||. |.. | |.| ..
rslsvlpeltilvadlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf........lkfIatqgpleitvvdfreepvlyyngwrmvlrg.
PLDNIVIVM---------------------VTPLVEYNrekcyqywprggvddtvriaskwespggandmtQFPSDLKIEFVNvhkvkdyytvtdiklTP
|. ..||| ..| ... .|. .|. . .
dlnvrdivmsrdevladelsrLdaAlgKtpllildgng.................................neptaadlellk...............ee
TDPLVGPVKTVHHFYFDLWKDmNKPEEVVPIMELCAHSHSLnSRGNPIIVHCSAGVGRTGTFIALDHLMHDTlDfknitersrhsdrateeytrDLIEQI
... . ... ... . | . . . |.... ... ..|.|..|||.||.||||||.... ||. . .|..
lydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkll.g....................vsleea
VLQLRSQRM-----KMVQTKDQFLFIYHAAKY
. ..|..|. .... .|..||..| ..
ledvrlkRpinpnpgfieqleqyefilealle
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 48-324 | 2.8e-29 | 96.7 | In-house | 41-231 (392) | alignment | ||
Range on Protein: 48-324
Range on HMM: 41-231/392.0
IEPRNDARNRYVNIMPYERNRVHL---KTLSGNDYINASYVKvnvpGQSIEpGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNrekcyq
.. | .||| ||.||...||.| . .||.||||.. . | |||.||| . |.||.| ... . |.||| | | .
qkeinlkknryknilpydsarvkleviddipdsdylnasyip....sfdne.kayiasqgpnaaslddfwrmvfqe...nvttiamvtklkegd......
ywprggvddtvriaskwespggandmtqfpsdlkiefvnvhkvkdyytvtdikltptdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSH-SLNS
..|| |.| | | . |. . .... . .
...........................................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGq
RGNPIIVHCSAGVGRTGTFIALDHLMHDTldfknitERSRHSDrateeytrdLIeQIVLQLRSQRMKMVQTKDQFLFIYHA
|.|.|||||||||| |..| .. . ...| | .. ..| ..| .| |||||.|. ||| |
ythpliihcsagvgrtgvvisidsvvaha.......kktrmvd.........vf.nfvtnirrkrpymvqtkeqyafiyga
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 51-323 | 5e-29 | 96.0 | In-house | 47-281 (305) | alignment | ||
Range on Protein: 51-323
Range on HMM: 47-281/305.0
RNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVnvPGqsiEPGYYIATQGPTRKTWDQFWQMCYHNCpLDniVIVMVTPLVEYNREKCYQYWPRGG
.. .||| .. ..|||.|.. .|| | || | .| .| || | || .|| ||. . .. | |. |.| .||..|..
qeagknrykdvgcldnnrvklegpwpheyihanyvst..pt...npkrfictqaplektcadfwymclqdk.ve..aifmlcnllekgakkcleyfaskd
vDDTVRIASKwespgGANDMTQFPSDLKIEFVNVHKVKdyytVTDIKLTPTDPLVGPVKTvHHFYFDLWKDMNKPEEVVPIMELCAHSHSlnSRGnPIIV
.|.. . | | . .| | ...|.. | | ||. .|. | |. |... | | | . |.|| ... . |.| ||.|
.kdvlefeek.....gqkisvkfessvtlkfrkdakak....vtetvlviegpgekarkv.thyhwidwpdrgvpaadlailellekarp..skg.pivv
HCSAGVGRTGTFIALDHLMHDTLDFKNITErsrhsdraTeeytrdliEQIVLQLRSQRMKMVQTKDQFLFIYH
|||||.||||. . |...... | . | . | ..|. ..| || . .|| .|.||..
hcsagigrtgsvvmleyildqllagqiied........t........dkilqkireqrnnsiqtdaqylfvhq
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 38-150 | 6.9e-29 | 95.8 | In-house | 33-140 (288) | alignment | ||
Range on Protein: 38-150
Range on HMM: 33-140/288.0
VNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKT---LSGNDYINASYVKVNVPGQsiepgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPL
... | .. ...|. .||| ||.||. .||.|| .|.|||||||.... . ||||||| .| ..||.. | | . |||.| |
lektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkk.....kyiatqgPladtvndfWelvyen...ktstivmltel
VEYNREKCYQYWPRGG
|| ...|| .||| ..
veggktkCeeYWPdad
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 51-323 | 8.3e-29 | 95.5 | In-house | 40-271 (307) | alignment | ||
Range on Protein: 51-323
Range on HMM: 40-271/307.0
RNDARNRYVNIMPYERNRVHLKTLS-GNDYINASYVkvnvpGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRG
| .||| .. ...|. .|. ||| | |. | .|.| .|..||| .| .|| |. . . ..|. ..| . || ||||
antdknryqdvkcqdkgrivvkfdglasdyihanyl.....giaikpkkficaqgplentqysfwamaiqe...kvesvimlckvielakikceqywple
GVDDTVrIASKwespGgaNdmTQFPSDLKIEfvNVHKVKDYYTVTDIKLTPTdplvGPVKTVHHFYFDLWKDMNKPEEVVPIMELCahsHSLNSRGNPII
. | ... . | | ..| .. .. .|. ||..|. . . .|..|. .. | | |. . ..| .. . ||..
egqklv.fgea....p..n..tisvanlgak..klapdedlinvttlkvdwa....qksrtiqhlqwenwpdrgvpqinltainll...eavrydtnpvv
VHCSAGVGRTGTFIALDHLMHDTLDFKNITErsrhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYH
|||||||||.|| .|. .. .. .| . ....| .||||| .||. |.|...
vhcsaGvGrsGtivaislvqdkmiaGinckd................mkklveelrsqrhyaiqteaqylylhr
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 97-328 | 1.3e-28 | 95.0 | In-house | 9-149 (152) | alignment | ||
Range on Protein: 97-328
Range on HMM: 9-149/152.0
GYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWprggvddtvriaskwespggandmtqfpsdlkiefvnvhkvkdyytvtdi
..||||||.. |...||.| ... . .|||.| |.| ...||.||.
fefiatqgpgpntladfwrmlkel...gittivmltellelgklkceqyi..................................................
kltptdplvgpvktvhHFYFDLWKDMNKPEEVVPIMELCAHSHS-LNSRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfKNitersrhsdrateeytrD
.... | |.. |. ...|. . . ..|.|..||||||||||||..|.. .. ..
................qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lg.................v
LIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
.|..| ..|..|...|....| |.| .|.|
sleeavalvrekRpgavpnpgqlrflyefekll
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 63-331 | 2.2e-27 | 91.2 | In-house | 1-173 (178) | alignment | ||
Range on Protein: 63-331
Range on HMM: 1-173/178.0
PYERNRVHLKTLSG---NDYINASYVKvnvpgqsiePGYYIATQGPtRKTWDQFWQMCYHncpldniVIVMVTPLVEYNREKCYQYWPRGGVddtvrias
|..|.||.| .|.| ||||||.. ||.|.....| . ....... . .||..|. .|....||..|||..
pldrtrvllsnleglersdyinaseil.........pglylgslpp.addlellkelgit.......hivnlteelelgflkcdpywpeeag........
kwespggandmtqfpsdlkiefvnvhkvkdyytvtdikltptdplvgpvktVHHFYFdLWKDMNKPEEVVPIMELCAHSHSLN-SRGNPIIVHCSAGVGR
...... . |.. |. ..|... ... ..|.|..|||||||||
...................................................iqylhi.pipDhgvpdllehflefvefieealdekggpvlVHCsaGvgR
TGTFIALDHLMHDTLDFKNitersrhsdrateeytrdlieqIVLQLRSQRMkMVQTKDQFLFIYHAAKYLNSL
.||..|.. ... |.. . .. ..|..|. .|.. .| ..| ...|..
sgtlvaaylmkklglslee......................aielvrerRp.ivpnpgqlrqLyefelrllke
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 50-274 | 4.3e-27 | 89.9 | In-house | 45-257 (418) | alignment | ||
Range on Protein: 50-274
Range on HMM: 45-257/418.0
PRNDARNRYVNIMPYERNRVHLKTL---SGNDYINASYVKVNVPGQsiepgyYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNREKCYQYW
.| ..||| ||.| .. ||.|| . |.||||| |. | | .|.|||| .| .||.| . | .|||.. | | || .||
khntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkq......fictqgplpntiadfwrmvwenrc...riivmlsresencrikcdryw
PRGGVDDTVRIAskwespGGANDMTqfpSDLKIEFVNVHKVKDYYTVT-DIKLTptdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCaHSH------
| . . | | |.. .|.|.| . . .| .|.|| . | . . .. .. | | | |. |. .| ||
peqiggeqfsiy......gngnevf...gtysvelveviqdpereiitrnirlt....fegetrditqyqyegwpdhnipdhtqpfrqll.hsitnrqnq
--SLNSRGNPIIVHCSAGVGRTGTFIALDHLMhDTLD
. | |||||||||||||||| . .| ||
iipssdrnvpiivhcsagvgrtgtfctavimm.kkld
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 77-324 | 8.8e-27 | 89.0 | In-house | 3-148 (151) | alignment | ||
Range on Protein: 77-324
Range on HMM: 3-148/151.0
NDYINASYVKvnvpgqsiepGYYIATQGPTRktwdQFWQMCYHncpLDNIVIVMVTPLVEYNreKCYQYWPRGGvddtvriaskwespggandmtqfpsd
.||||.||| |......||. .|... .. |. .||......|.. .|..|.|. |
sdyinfsyvt..........gglyrsggpla....dflellke...lgiktivnlrseeerg..ycpeylpelg..........................
lkiefvnvhkvkdyytvtdikltptdplvgpvKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSlnSRGNPIIVHCSAGVGRTGTFIALDHLMHDtldfk
.|.|.... |.| . |. ..|. . . ...|..||||||.|||||..||. ....
................................ievlhipildwpdpglplsfdavleflellld..kkngpvlvHCsaGkgRTGtlvalylmllg.....
nitersrhsdrateeytrDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA
.|... ..|..|. .||...||||...|
..................vsleealeeyrlkrpgvvqpnqqflfqlfa
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 52-323 | 2.7e-26 | 87.2 | In-house | 35-264 (285) | alignment | ||
Range on Protein: 52-323
Range on HMM: 35-264/285.0
NDARNRYVNIMPYERNRVHLKTLsGNDYINASYVKVNVPGQSiepgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRGgV
| ||| .. | || || ||| ||.... || ||.|||| .| .||.| |.. ..|. |.| ||| |.| .
npdlnryadvrcieetrvvlknh.drdyihaswmrmpgkdqs....tyittqgplpetlsdfwhmiyqe...kiayvlmlctlfeggvekcalyypek.l
DDTVRIaSKWEspggandMTQfpSDLKIEFVNvHKVKDYYTVTDIKLTPTDPLVgpvktVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVH
. |.. |.| .| .. | | . . . ||.. . . ..|| . | | | ||. |..|| . .| . .|| ||
gevvkf.gkye.......itl..teckeeaia.gtilnaltvintedasseply.....mnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvh
CSAGVGRTGTFIALDHLMHDTLDFKNItersrhsdratEeytrdLIeQIVLQLRSQRMKMVQTKDQFLFIYH
|||||||| ||. .|. .. || | .. .|| ..|. |.. ||.. ||||.|
csagvgrtatfvgidyatirimenpni...........e.....ml.divremramrfqavqshmqflflyv
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 46-151 | 1.4e-25 | 85.0 | In-house | 40-140 (318) | alignment | ||
Range on Protein: 46-151
Range on HMM: 40-140/318.0
VSIEPRNDARNRYVNIMPYERNRVHLKTLS---GNDYINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKC
|.|| | |.|||.||..|.. ||.|..|. | |||||.|. | . |||.|.| .| . ||.| . . ||||.| ..| ..|.
kslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyid....Gyr.rkkayiaaqaPlpetieDfWrmvWeq...nsavivmltqeeergkakv
YQYWPRGGV
.||| |
hryWPskgs
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 45-323 | 5e-25 | 83.0 | In-house | 26-253 (267) | alignment | ||
Range on Protein: 45-323
Range on HMM: 26-253/267.0
GVSIEPRNDARNRYVNIMPYERNRVHLKTlSGNDYINASYVKVNVPGQsiepgYYIATQGPTRKTWDQFWQMCY-HNCPldniVIVMVTPLVEynrEKCY
|| |..|||. . .||. .|| |.| . ..|||||||. .. .|.||.| ..| .|... ...| |||..|. . ..
sqsiaeknqernrlddnlpyddtrvilrt.keeeyinasyvegyktkn.....afivtqdplkntitdfltvihdqkvp....vivlltkvft...dnir
QYWPRggvddTVRIASKWEspggandmtqfpsDLKIEFVNVHKVKDYYTVTdIKLTPTDPlvgPVKTVHHFYFDLWK-DMNKPEEVVPIMELCAHShSLN
..|| . | |.. || .|. .. .|| .| ..| . . | .|. |. . |. . |.. . |. |.
lfwPP.....kmgqakkyq.............dltvehslekeendyqiit.lelkfkne...sahnvtlyyykkwnintnnkpylkplfgilakn.qle
SRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYH
..|..|.||.||||.|||. .| . .|| .| . | | . ....||||. .|.||.....|..
ngnrPlvvacsdGvGrsGtflvidsql................eraktegvsd.ifdflrkirsqriglvdtkeryiyihe
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 51-323 | 8.6e-25 | 82.0 | In-house | 41-284 (296) | alignment | ||
Range on Protein: 51-323
Range on HMM: 41-284/296.0
RNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKvnvpgQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNReKCYQYWP
| .||.|...||. ||| |..| |. |||||.|| . . || |..|...| |.||.. | . . .|..| .... .. .|||
enreknrdvkvvPyDynRvvLekldGeeksdYinavyvd.....sflkkkeyivteapkketvdefWrlvyde...eisavvvLtktfdfak.mypsywp
RGGVDDTVRIASKWespggaNDMTQFpSDLKIEFVNVHKVkdyytVTDIKlTPTDPLVGPVKTVHHFYFDLWKD-MNKPEEVVPIMELCAHSHSLNSRG-
. . | . . |. ..||| . . | . . . . . ....|..| . |. . | ..|| ... .
nkskeqygeifvei......veekqy.anlkirtfkltkk.....ivalt.eqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvd
-----NPIIVHCSAGVGRTGTFIALDHlmhdtldfkNItersrhsDRATEEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYH
.|..|..| |..|.| ..|.| |. . . .| |. . | .|| .| ..|...... .||
edpeegPvvvvssdGasRsGvylaida.........nl.......elvekeeevdvF.eavktlrrsRpqLvenveeYkyiYd
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 176-325 | 1.1e-24 | 82.1 | In-house | 145-276 (318) | alignment | ||
Range on Protein: 176-325
Range on HMM: 145-276/318.0
DLKIEFVNVHKVkDYYTVTDIKLTPTDplVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN--SRGNPIIVHCSAGVGRTGTFIALDHLMhdtl
.|..| . .. ..|.. .|.| |. . ...|. . . | | . ||... ...| .... . | .||.|||||||||||.|||.| |.
klvvelkeevel.sdyvlrefkvtrte..eeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdill....
dfknitersrhsDRATEEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYHAA
.|. .| . |. |.| |||.|| ||||.||. |||..
............erikaealvDvf.qtvkqlreqrnlmvqtedqyefiydvl
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 46-149 | 2.8e-24 | 80.5 | In-house | 25-125 (297) | alignment | ||
Range on Protein: 46-149
Range on HMM: 25-125/297.0
VSIEPRNDA--RNRYVNIMPYERNRVHLK-TLSGNDYINASYVKVnvPGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKC
| || . .||| .|. .. .||.|. . ...||||| || | . .. .|| .|||...| |.||.. ... | |||||. | | |.||
fssakrnsslrknryrdilatddtrvkllrviterdyinadyvvf..pdee.adlkyilaqGplsatvddfwtlvaeq...dvrvivmvaklqedGrdkc
YQYWPRG
. |||.
apywpsv
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 51-148 | 2.1e-23 | 77.8 | In-house | 2-93 (237) | alignment | ||
Range on Protein: 51-148
Range on HMM: 2-93/237.0
RNDARNRYVNIMPYERNRVHLKTL-SGNDYINASYVKvnvpGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
.| ..||| ||. |. .|| || || |||||.|.| | | |||.||| . |.|||| . . ||||.| |.| |..||..|||
enkiknrygnivaydhsrvvlkgagsgsdyinatylk....gfdgtpkkyiaaqgplesscddfwqmvwqe...kcsvivmltgliegnelkchkywps
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 207-324 | 8.3e-23 | 75.8 | In-house | 173-274 (288) | alignment | ||
Range on Protein: 207-324
Range on HMM: 173-274/288.0
PVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRG-NPIIVHCSAGVGRTGTFIALDHLMHDTLDfknitersrhsdrateEYTRDLIeQIVLQLR
..... . | |.. || |..|| . |. .|||||||||||||||||||| |.. | . |.. .| .||
teleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidavee................edyiDva.gtvaklR
SQRMKMVQTKDQFLFIYHA
||. .|||. |. |||..
kqRallvqtlkqYefiyev
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 52-323 | 1e-22 | 75.2 | In-house | 55-283 (305) | alignment | ||
Range on Protein: 52-323
Range on HMM: 55-283/305.0
NDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVpgqsIEPGYYIATQGPTRKTWDQFWQMCYHNCpLDNivIVMVTPLVEYNREKCYQYWPRG-G
. ..||| .. ... |.|. | ||| | || . . | .|..||| .| |.|| | .| ... |||. || . || |||| |
aitknryqdvpcqdqsavkldkpspsdyihanyvgcpm....ipekrficaqgpldqtidefwwmviqnk.veq..ivmlcktvelgklkcaqywpaaqg
VDDTVRIASKWESPGGANDMTQFPsDLKIEFVNVHkvkdyYTvTDIKLtptdplvgpvkTVHHFYFDLWKDMNKPEEVVPIMELCAhshSLNSRGNPIIV
... | |.. | . . ...| .|. |. | |. .| |. . | | | . .|| . .. ||.|
eklelksgivvenvsgskpmerda.eiqitllnlt.....ys.gdqkm...........svrhlqwtewpdrgvppckltslells...airgskvpivv
HCSAGVGRTGTFIALDHLMHdtldfkNITERSRHSDrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYH
|||||.||||| .|..... .|.| . . ..| || || .|. |.|||.
hcsagigrtgtivaieyile......kiaenkpcpp..........mpelvkalrdqrafsiqndvqylfihr
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 44-149 | 1.5e-22 | 75.0 | In-house | 39-135 (287) | alignment | ||
Range on Protein: 44-149
Range on HMM: 39-135/287.0
LGVSIEPRNDARNRYVNIMPYERNRVHLKTlSGNDYINASYVKvnvpGQSiEPGYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNREKCY
. ..| ..| .||. .|.... .|| || .|||||.... | . | .|....| .| .||.. .. . .|||.. . | ..|.||
vthniasqnkdknRltqilvpdnyrvllkg.ehpdyinavfid....gyk.ekkafiiaesPmfntarnfWkliddrnv...taivmlcqekendeevcy
QYWPRG
|||| .
qyWpee
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 194-328 | 4.8e-21 | 70.4 | In-house | 34-142 (145) | alignment | ||
Range on Protein: 194-328
Range on HMM: 34-142/145.0
TDIkltpTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHdtldfknitersrhsdrateeYT
.. |. | ...... .... | |.. |. ..|... ... ..|.|..||||||||||||..|.. ... .
lnl....tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....................lg
RDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
. .|... ..||||...|.. .|. |.| . ..|
vs.leealelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 187-327 | 6.8e-21 | 69.9 | In-house | 25-143 (144) | alignment | ||
Range on Protein: 187-327
Range on HMM: 25-143/144.0
VKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsd
|.. | | ||.. . . ........ | |.. |. . |... ... ..|.|..||||||||||||..|.. ..
lkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.................
rateEYTRDlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY
.. . .|... ..||.|. .|.. .|. |.. |.
....klgls.leealalvrsrrpgavpnpgqlrfLleyekl
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 52-326 | 1.5e-20 | 68.4 | In-house | 43-268 (288) | alignment | ||
Range on Protein: 52-326
Range on HMM: 43-268/288.0
NDARNRYVNIMPYERNRVHLKtlsgnDYiNASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRGgV
| .|.|| |. . ||.|. | |...|| . . | .| | . | ...|.| .. | |||.. |.| .|| .|.| .
nptrdryenlprcditrvkls.....dd.pdfyiaanvvssakykrrlicaqaPlngtieelWkmlles...dveyivmlcellekGkeksaeyfPsk.l
DDTVRIASKwespggandmtqfPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPlvgpvkTVHHFYFDLWKDMNKPEEVVPIMELCAHShslNSRGNPIIVH
...|| .. | . ....|. .. | . . | . .. |.| ||. .. . |. .| .||.||
Gekarigrl.............ctvvkkkradidklvkvsllriskegeekv......ivkilhlleWdddgvPenylsplrllevl...kslqkPivvh
CSAGVGRTGTFIaLDhLMhdtldfknITERSRHSDRATeeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
.|||||||||.| | |. . | | .| . |.... .|| .|.| .||. |.|... .
ssaGvGrtgtli.li.li........aleslrlddflg.......irsllaklreerfkaiqtemqylyvhrcvl
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 52-148 | 1.5e-19 | 65.1 | In-house | 8-100 (239) | alignment | ||
Range on Protein: 52-148
Range on HMM: 8-100/239.0
NDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKVNvPGqsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
| |.||| ||. |...|| |. || .|||||||.. | | |||||| . .||.| ... ||||.| |.| ..||.||||
nkaknryanivtydhsrvvleklsndphsdyinasylrdy.dg...spkayiatqgcveissgdfwrmmwqe...rrcvivmltglieghkkkchqywpd
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 52-148 | 1.6e-19 | 65.0 | In-house | 7-99 (239) | alignment | ||
Range on Protein: 52-148
Range on HMM: 7-99/239.0
NDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKVNvPGqsiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
| |.||| ||. |...|| |. || .|||||||.. | | |||||| . .||.| ... ||||.| |.| ..||.||||
nkaknryanivtydhsrvvleklsndphsdyinasylrdy.dg...spkayiatqgcveissgdfwrmmwqe...rrcvivmltglieghkkkchqywpd
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 48-151 | 3.5e-19 | 63.6 | In-house | 52-151 (297) | alignment | ||
Range on Protein: 48-151
Range on HMM: 52-151/297.0
IEPRNDARNRYVNIMPYERNRVHLKTL---SGNDYINASYVKVNVPGQSIepgyYIATQGPTRKTWDQFWQMCYHNCpldNIVIVMVTPLVEYNREKCYQ
...| .||. ...||. .||.||. . .|||||| . . | ... ||||||| .| .|||| ... .|||..|.| | . ..|..
kaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapa....yiatqgplastvadfwqmvweqG...vvvivnltrleeegvkqckr
YWPRGGV
||| |
ywpdeGs
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 51-148 | 1.8e-18 | 61.3 | In-house | 37-128 (287) | alignment | ||
Range on Protein: 51-148
Range on HMM: 37-128/287.0
RNDARNRYVNIMPYERNRVHLK--TLSGNDYINASYVkvnvPGQSIEpGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
. .||| ...|.. .|| | . | ||||| || .. . .||.||| | .||.. ... .....| || | |||.|||
aavkknryadvlPiddtrvllsaegelGsdyinanyv....asytdd.eafiaaqgPiaatvrdfwravlet...rsasvitmtreveearlkcykywPe
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 51-322 | 2.3e-18 | 60.8 | In-house | 51-283 (310) | alignment | ||
Range on Protein: 51-322
Range on HMM: 51-283/310.0
RNDARNRYVNIMPYERNRVHLKTL--SGNDYINASYVKVNVPGQSiepgyYIATQGPTRKTWDQFWQMCYHNCpldNIVIVMVTPLVEYNREKCYQYWPR
.. .||| ... . ||.|| .||| | ||| | .. .| .||| ..| .||.| . . |... .| | || |||
kymhknrysdvvcldtsrvklkidksryedyihanyvktnylrst.....ficsqgplqhtiidfwrmifqer...aesilllckvgeegrpkcvgywps
GGVDDTVRIASkwespggANDMTQFPSDLKIEFVNVHKVKDYYTVTDiklTPTDplvGPVKTVHHFYFDLWKDMNKPEEVVPIMelcAHSHSLNSRGNPI
|| .| .... ...| . | | | | . |.. | . | |. |.| . . . | |
lgvtetygcir.......vtnlsesseefeicnlavtfvpdnvpvde...qpan...lkelrvslikwpnwpdrgvpdekchtv...pqrllaqvrhgpc
IVHCSAGVGRTGTFIaldhlmhdTLDFKniTERSRHSDRATeeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIY
.||||||..|... . .|..| ..... .. .|... .|. .|.. .||. |.|.|
vvhcsagkdrlyvvv........alklk..idkldrglkvd.......aeevktellksraiciqtelqyliid
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 94-320 | 2.9e-18 | 60.6 | In-house | 87-272 (301) | alignment | ||
Range on Protein: 94-320
Range on HMM: 87-272/301.0
IEPGYYIATQGPTRKTWDQFWQMCYHNcPLDNivIVMVTPLVEYNREKCYQYWPRGGVddtvriaskwespggaN--DMTQFpsDLKIEFVNVhKVKDYY
.| .|||||| ..| . || |. . ... |||.. ||.. ||| .| | . |. .| ..||. .. ...
GhphrfiatqgPlkntsedfwamlvqy.dvek..ivmlgqkvekleekceeylpvkis................ekldigrf..kikiknkel.ilnkki
TVTDIKLTPTDPLVgPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHshsLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLdfknitersrhSDRATEe
. .... . . . .|| |. . | | . |. . ...| . .||.||||||.||. .||. . | .. . .|. |
skrtlevedstgkf.atrtvthyqysewtdrgvPkshaelfdlmel...vkksekPivvhcsaGiGrsvafigteylareve...........adptie.
ytrdlIEQIVLQLRSQRMKMVQTKDQFLF
. . . .|| .| . |||. |. .
.....ltealkhlrehrwngvqtnsqlyw
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 44-148 | 4.1e-18 | 60.4 | In-house | 41-140 (315) | alignment | ||
Range on Protein: 44-148
Range on HMM: 41-140/315.0
LGVSIEPRNDARNRYVNIMPYERNRVHL---KTLSGNDYINASYVkvnvPGQSiEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNRE
| |. . | .|||.||..|.. ||.| .. .. ||.||... .| . . |||.||| . . ||.. ... | |||.| ||| ...
ldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfi....dGyn.kkrryiaaqgpnvasvkdfwrlvfee...digkivmltnlvegekr
KCYQYWPR
|. .|||
kaekywpd
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 207-324 | 1.1e-17 | 58.9 | In-house | 173-274 (315) | alignment | ||
Range on Protein: 207-324
Range on HMM: 173-274/315.0
PVKTVHHFYFDLWKDMNKPEEVVPIMELCA--HSHSLNSRgNPIIVHCSAGVGRTGTFIALDHLMhdtldfknitersrhsDRATEEYTRDLIeQIVLQL
...| . . | ||. |. .|.|.| . | || .|.||||||||||||||.|| .. |.| | |. ... ..
nirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavl................dqaeaenaidvy.nfitgv
RSQRMKMVQTKDQFLFIYHA
|..|.||||. .|. ||| |
rqnrikmvqvaeqyqfiyda
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 55-269 | 1.8e-17 | 58.0 | In-house | 46-233 (312) | alignment | ||
Range on Protein: 55-269
Range on HMM: 46-233/312.0
RNRYVNIMPYERNRVHLKTlSGNDYINASYVKVnvpgqSIEPGYYIATQGPTRKTWDQFWQMCYHncpLDNIVIVMVTPLVEYNREKCYQYwprggVDDT
||| || ..| | | | || | .||. | ...|||| .| .|||.. | . |.... .|| ||| .| . |
lnrypniqcwdrgrftlag.denfyihanfvki.....ctkperfvctqgplentcthfwqlals...lgstsiillcgfvedgsekcaky.....isdi
VRIASKWEspggANDMTQFPSDLKIEfvnvHKVKDYYTVTDIKLTPTdpLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAhshSLNSRGNPIIVHCSA
| . . |.. ....| | || | .|. | . |. . | | |. . . | . ... .|.| ||||
vgfvdled....hrvyteycteieig....gkskdkithrvlkvvvk..atgqesklnhyqwaswpdhgmpdscdtalrlls...avkkdkkpviahcsa
GVGRTGTFIALDHLM
|||||||.. .. ..
gvgrtgtlaliesmi
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 45-152 | 3.1e-17 | 57.2 | In-house | 33-137 (301) | alignment | ||
Range on Protein: 45-152
Range on HMM: 33-137/301.0
GVSIEPRNDARNRYVNIMPYERNRVHLKTLSG-----NDYINASYVKvnvpgQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPldnIVIVMVTPLVEYNR
|... .| | ||. || .|. ||. ||. . ..||||||.. | .||.||| .|| .||.. ... | . ||||| | | .
tvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyid.....gysekkkfiaaqgpmkktlvdfWrliwqekp...vsivmvtnlkegtk
EKCYQYWPRGGVD
.||.||||.. .
skceqywpnseae
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 233-325 | 1.6e-16 | 54.6 | In-house | 253-340 (349) | alignment | ||
Range on Protein: 233-325
Range on HMM: 253-340/349.0
ELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHdtlDFKNITERSRHSDraTEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
.| |. . ... ....|||||| ||||... || |. .. .. | . . ..||| || .|| ||. ||| || .||.|
dlfarlyldtdqlstllvhcsaGcGrtGvlvtldllls...ileplqnesnkik..lqallkDlisiivnelrkqrismvqnlaqfiaiyeal
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 49-149 | 4e-16 | 53.5 | In-house | 34-130 (281) | alignment | ||
Range on Protein: 49-149
Range on HMM: 34-130/281.0
EPRNDARNRYVNIMPYERNRVHLKT----LSGNDYINASYVKVNVpgqsIEPGyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQ
.| |. .|||.|| . ||.|| ||| | |.. . .. | || |||| ..| .||.| ... . |||. ..| ||||| .
qpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspf....lkrg.yiltqgpkketradfwrmiwqe...nttaivmlcqfletnrekcae
YWPRG
|.||
yfprn
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 43-325 | 6.7e-16 | 52.8 | In-house | 31-266 (307) | alignment | ||
Range on Protein: 43-325
Range on HMM: 31-266/307.0
SLGV--SIEPRNDARNRYVNIMpyERNRVHLKTLSG---NDYINASYVKvnvpGQSIEpGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEY
|| | . .. ||.. |. . ||.|. | .|.| | .|| |. . .| .| | . | |.||.| . . . |||.| .|
slttaasdnnlekarskrvhck..dssrvklelrrGqylddfihanrvk....Gkpll.nefilaqaplkntvddfwrmvfqe...evqyivmltsrkes
nrEKCYQYWPRGGVDDTVRIaskwespggandmtqfPSDLKIEFVNVHKVKD-YYTVTDIKLtptdplVGPVktVHHFYFDLW-KDMNKPEEVVPIMELC
|.| |||. | | . | |.|| ..|.. | ..|| .|| ||. . . | |.|. .| ...
..erceyywpkaesdslvtv................pGslrienlkvdskadplfrvtklkl......vGgd..deerflehwqgdvnnssdvysplrvl
AHshsLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLdfknitersrhsdRAteEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAA
. | .|..|.. || ...|..|.. . . | | |. |. . | || .| |.. ..||.|
rk...lrnlskpvvvqdilGvskaatlvaieiallsll.............rG..pitkslvlravvflrlrrrlsvesvllylfvyrlv
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 207-324 | 1.9e-15 | 51.3 | In-house | 172-274 (439) | alignment | ||
Range on Protein: 207-324
Range on HMM: 172-274/439.0
PVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS--RGNPIIVHCSAGVGRTGTFIALDHLMHdTLDFKNitersrHSDrateeytrdlIEQIVLQL
.|| .|.. | | | | . .... | | |..|||||||||||| |||| . | .| . | |. || |
kertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdiale.qlklen......kvd..........ikgivkvl
RSQRMKMVQTKDQFLFIYHA
| || .|||. |..||| |
rkqrkqmvqalcqyvfiyna
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 207-324 | 2.1e-15 | 51.2 | In-house | 185-287 (297) | alignment | ||
Range on Protein: 207-324
Range on HMM: 185-287/297.0
PVKTVHHFYFDLWKDMNKPEEVVPIMELCAH-SHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHdtldfkNITERSRHSDrateeytrdlIEQIVLQLR
.|| |.| |.... | . ...|. | | ||.||||.|.||||..|..| ... ... .. | | . ||
etrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvln......rllkGvkeid..........iaatlehlr
SQRMKMVQTKDQFLFIYHA
|| ..|.||||| |.. |
dqrpglvktkdqfefalta
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 176-329 | 2e-14 | 48.3 | In-house | 142-279 (287) | alignment | ||
Range on Protein: 176-329
Range on HMM: 142-279/287.0
DLKIEFVNVHkVKDYYTVTDIKLTPTDpLVGPVKTVHHFYFDLWKDMNK-PEEVVPIMELCAHSHSLNSRGN-PIIVHCSAGVGRTGTFIALDHlmhdTL
. .||..| . |.. |.. ..... .. |. ..|. . . |.. | .| .. . .. ||| .|.||||..|||...|.| . |.
eyniellnee.vnagyierklevknkn.kagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaat....ti
dfknitersrhsDRATEEYTRDLIeQIVLQLRSQRMKMVQTKDQFLFIYHAA-KYLN
... .| . |.. |.. . | |....||| .|. ||... .||.
............nkckteGviDvf.qvlksqriqkpgsvqtveqykfindivleyld
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 53-148 | 8.8e-13 | 42.5 | In-house | 55-142 (290) | alignment | ||
Range on Protein: 53-148
Range on HMM: 55-142/290.0
D--ARNRYVNIMPYERNRVHLKTLSGNDYINASYVKvnvpGqsIEPgYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
.||| ... .. || || ||. | ||| | ... .| |||....| ..|.| .. . .|||. |.| . || ||.|
tefkknrykdvvcndktrvilkdGydGdyvhanyvk....G..lka.mfiltqGalkdtvidiwrmvlqe...kvaaivmlceliedGkakceqyype
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 50-239 | 3e-12 | 40.8 | In-house | 26-191 (319) | alignment | ||
Range on Protein: 50-239
Range on HMM: 26-191/319.0
PRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKvnvpGQSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYW
. . ..|..|..| || |. . . |..||||. |. | .|||.| . .. .||.. . . ||| .| | | ..| .|.
vtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvr....Gyddapnsyiaaqvsledsssdfwrtvweq...qsrvivqltdlselGikvcaeyl
PrggvddtvriaskwesPGGANDMTQFPSDLKIEFvNVHKVKDYYTVTDIKLTPTDPLVgpVKTVHHFYFdLWKDMNKPEEVVPIMELCAHSH
| . . | |. |... . .||| | .. . | | . . |... | . . | | ... . . .
P................tketldntslyGdilvtl.kgrevkdryaistlllkrvdkee..srelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 52-149 | 3.6e-12 | 40.5 | In-house | 48-135 (439) | alignment | ||
Range on Protein: 52-149
Range on HMM: 48-135/439.0
NDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKvnvpGqSIEPGYYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNRekcyqYWPR
....||| .. ... || |. . | |||| |.| | .. |||||||...| |.||.. ... . |||.| ||| . |||
dqtknrykdvgafdhtrvtlqeipgvphshyinanyik....G.yyddklyiatqgpkkettddfwrlviek...ktvtivmltnlvesyk.....ywps
G
d
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 98-267 | 5e-12 | 40.4 | In-house | 5-156 (198) | alignment | ||
Range on Protein: 98-267
Range on HMM: 5-156/198.0
YYIATQGPTRKTWDQFWQMCYHNCpldNIVIVMVTPLvEYNREKCY-QYWPRggvddTVRIASKWESpggandMTqfpsdlkIEfVNVHKVKDYYTVTDI
||||| | |.| .|||| . |||| . |.| | ||| | ..|. | .. . ... .| ||.| .
ryiatqhplretladfwqmvwetg...sghivmvndd.qknkeadypfywpt.....tesgtgkygs......ls.......vt.tktittkpdytital
KLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAhSHSL-----NSRGNPIIVHCSAGVGRTGTFIALDH
|| . . |. | ||. |. . . . | | . . . |.||||| | | || |.|||
iltnnttappstreishyqftswkekttpnvalfvgfvva.srevskkyeqekdapvivhcsdgqgftgvfvaldi
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 98-267 | 6.8e-12 | 40.0 | In-house | 6-157 (199) | alignment | ||
Range on Protein: 98-267
Range on HMM: 6-157/199.0
YYIATQGPTRKTWDQFWQMCYHNCpldNIVIVMVTPLvEYNREKCY-QYWPRggvddTVRIASKWESpggandMTqfpsdlkIEfVNVHKVKDYYTVTDI
||||| | |.| .|||| . |||| . |.| | ||| | ..|. | .. . ... .| ||.| .
ryiatqhplretmadfwqmvwetg...sghivmvndd.qknkeadypfywpt.....tesgtgkygs......ls.......vt.tktittkpdytital
KLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAhSHSL-----NSRGNPIIVHCSAGVGRTGTFIALDH
|| . . |. | ||. |. . . . | | . . . |.||||| | | || |.|||
iltnnttappstreishyqftswkekttpnvalfvgfvva.srevskkyeqekdapvivhcsdgqgftgvfvaldi
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 243-326 | 1.3e-11 | 38.7 | In-house | 245-312 (319) | alignment | ||
Range on Protein: 243-326
Range on HMM: 245-312/319.0
SRGNPIIVHCSAGVGRTGTFIALDHLMHDtLdfknitERSRHS-DrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAK
.. |..|||| ||||||. || | .. | | |..| | | |.| ..| .| . |.||.|. |||. .
esqGPlvvhcsdGvGrtGlviasdiairs.l......eeskrsvd..........iPqlvssvrrdrasavltkeqyefiykvls
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 104-268 | 2.8e-11 | 37.4 | In-house | 98-244 (302) | alignment | ||
Range on Protein: 104-268
Range on HMM: 98-244/302.0
GPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPRgGVDDTVRIASKwespggANDMTQFPSDLKiEFVNvhkvKDYYTVTDIKLTPTDP
| ..| ...| . . . ..| .. .|| . .|| .|. |..... . . ||. || . | ... .... .
vpkkstlekhwalieqy...nvaivvqlcsfvedeekkcaeyysd.kvggelkfgry......tvktvsvktdle.eftd....kksfklytveiknekk
LVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNsrgNPIIVHCSAGVGRTGTFIALDHL
|||. ..| | | |.| . ... . | . ..||||||||||||..|. .
kkkvkktvdilafsawpdhGapkeaytaldilkfcesyk...knvlvhcsaGvGrtGtlvaikyG
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 53-162 | 1e-10 | 35.5 | In-house | 49-170 (349) | alignment | ||
Range on Protein: 53-162
Range on HMM: 49-170/349.0
DARNRYVNIMPYERNRVHLKTL-----------------SGNDYINASYVKVnvPGQSIEPgYYIATQGPTRKTWDQFWQMCYHNCpldNIVIVMVTPLV
|.||| .|.||| || || .||||| |.|. . |.| ||||| | | | |... | ... ..
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkl..trisvek.kyiatqaPlPstvddfykvillng...vklvlsLnddk
EYNREKCYQYWPRGGVDD-TVRIASKWE
| . |||..|| . .. ||.. ..
elslekcdiywqelsysnitvklqnssl
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 191-323 | 1.3e-10 | 35.9 | In-house | 116-233 (237) | alignment | ||
Range on Protein: 191-323
Range on HMM: 116-233/237.0
YTVTDIKLTPTDPLVgPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHS--HS-LNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNItersrhsDr
||| . |. | |. .| . | | | |.. .. . . .| |. | |.|||||||||| |. .| ..... . | . |
ytvrslllskrltlk.evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvv.......d.
ateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYH
| . | . .| ..|||||..||..
.........iynyvysieedrpyiiqtkdqyvfihq
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 210-324 | 1.8e-10 | 35.4 | In-house | 138-236 (239) | alignment | ||
Range on Protein: 210-324
Range on HMM: 138-236/239.0
TVHHFYFDLWKDMNKPEEVVPIMELCAHS--HSLNsRGNPIIVHCSAGVGRTGTFIALDHLMHDtldfknitersrhsdrATEEYTRDLIEqIVLQLRSQ
|....| .| | |. .. | . || | ..||||||||||.|. .| .... | .. | |... | .| .
yvyqyhftvwpdkgvpqyatavlglrrkitkdslp.garpwvihcsagvgrtgaflvidamlrq................akkqktvdifn.yvkaired
RMKMVQTKDQFLFIYHA
| .|||| .|..||. |
rphmvqtseqyvfihla
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 210-324 | 1.8e-10 | 35.4 | In-house | 137-235 (239) | alignment | ||
Range on Protein: 210-324
Range on HMM: 137-235/239.0
TVHHFYFDLWKDMNKPEEVVPIMELCAHS--HSLNsRGNPIIVHCSAGVGRTGTFIALDHLMHDtldfknitersrhsdrATEEYTRDLIEqIVLQLRSQ
|....| .| | |. .. | . || | ..||||||||||.|. .| .... | .. | |... | .| .
yvyqyhftvwpdkgvpqyatavlglrrkitkdslp.garpwvihcsagvgrtgaflvidamlrq................akkqktvdifn.yvkaired
RMKMVQTKDQFLFIYHA
| .|||| .|..||. |
rphmvqtseqyvfihla
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 206-278 | 5.9e-10 | 33.3 | In-house | 180-249 (290) | alignment | ||
Range on Protein: 206-278
Range on HMM: 180-249/290.0
GPVKTVHHFYFDLWKDMNKPEEVVPIMELcahSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNI
| . ..|. | | . . .. . ..| |..||||||.||||||.|.. . || |..
Gkehklkhlkikswpdksvalstlallrt...lrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkel
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 243-325 | 2.3e-09 | 31.6 | In-house | 226-291 (297) | alignment | ||
Range on Protein: 243-325
Range on HMM: 226-291/297.0
SRGNPIIVHCSAGVGRTGTFIALDHLMhdtldfkNITERSRHSDRATeeytrdlieqIVLQLRSQRMKMVQTKDQFLFIYHAA
| ...|||||||||.| . | .. ... . | | |. |. .||.|| ..||| .|| ..|.|.
prnayllvhcsaGvGrsGvvvlsdvil.......aklrkkripdvaa..........ilsilreqrarlvqtleqfellydav
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 209-325 | 2.7e-09 | 30.9 | In-house | 89-190 (440) | alignment | ||
Range on Protein: 209-325
Range on HMM: 89-190/440.0
KTVHHFYFDLWKDMNKPEEVVPIMELCAHS-HSLNSRGN-PIIVHCSAGVGRTGTFIALDHLMHDTldfknitersRHSDRAteeytrDlIEQIVLQLRS
.|....... | | |. . |.... .| . || |..||||||.|||| ||.| ..... ..||. | | .. .|.
rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilrea..........krsdqi......d.ifsfinsmrn
QRMKMVQTKDQFLFIYHAA
.| .|||| .|. |...|
nrpqmvqtpeqyafvheav
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 206-323 | 6.1e-09 | 29.9 | In-house | 164-263 (281) | alignment | ||
Range on Protein: 206-323
Range on HMM: 164-263/281.0
GPVKTVHHFYFDLWKDMNKPEEVVPIMELCahsHSLNSRGNPIIVHCSAGVGRTGTFIALDhlmhdtldfknITERSRHSDrateeYTRDLIEQIVLQLR
| . . |. . | | . || .... . . .| | ..||||||||.||..|.. |. .| || .| |.||| .||
getrlithwlwkewpdwqvpessevmlkil...rkirarstppvihcsagvgrsgtlmave...........ialqsihsh.....ftlpdikqivshlr
S-QRMKMVQTKDQFLFIYH
| ||| .|...|..
vtgraasvqtlqqymliwk
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 181-328 | 8.1e-09 | 29.3 | In-house | 152-284 (302) | alignment | ||
Range on Protein: 181-328
Range on HMM: 152-284/302.0
FVNVHKVKDYYTVT---DIKLTPTDPLVGPVKTVHHFyfDLWKDMNKPEEVVPIMELCAHSHSLNSRGN-PIIVHCSAGVGRTGTFIALDHLMHdTLdfk
|||. ||. . | . | . .. .| .. . ||. . |... ... |. . ... .. .... |.|| |.|..| .. .|
fvNnrkVekaeeektryviEvlPegcsnsvlanvyvl..tnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavave.kl...
niTERS--RhsdrateeytrdlIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYL
.. . . |..|| ..|||| ..|.. .|. ..| |. ..
..qkgkepn.............ikeivksiRsqRpravdslkQyvslyiallly
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 47-130 | 1.1e-08 | 29.0 | In-house | 91-168 (244) | alignment | ||
Range on Protein: 47-130
Range on HMM: 91-168/244.0
SIEPRNDARNRYVNIMPYERNRVHLK-TLSGNDYINASYVKvnVPGQSIEpgyYIATQGPTRKTWDQFWQMCYHNCplDNIVIVM
...| | .|| .|.. ||| | || |||||.| |.. | || || | | .||.| |...|.
afnpnnswknregaglpfdfnrvplskgsmgntyinasfvg..clgrtae...yiltqhpladtsmdfwkmmlerh..vnvlvvl
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 51-87 | 7.2e-08 | 26.5 | In-house | 47-83 (95) | alignment | ||
Range on Protein: 51-87
Range on HMM: 47-83/95.0
RNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKV
| .||..||.||. || | | ||||| .|
anipknrflnifpydatrvvlttkrdsdyinacfvdg
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 209-315 | 7.7e-08 | 26.7 | In-house | 116-207 (255) | alignment | ||
Range on Protein: 209-315
Range on HMM: 116-207/255.0
KTVHHFYFDLWKDMNKPEEVVPIMELCAHSHslNSrgNPIIVHCSAGVGRTGTFIaldhlmhdtlD----FKNITERSRHSDRATEEYtRDLIEqivlQL
.||.|. . | . | ||. |... . .| ...||||.|.||. .|. .... . .. . .| . |.| .|
htvkhysykGWieknaPelareilnilkvvr..ds..ksvvvhCstGiGrsaafv..........laelvyqkmirsldttetveldy.lslle....el
RSQRMKMVQTK
||.| . ..|
rskrkraihtP
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 224-265 | 9.5e-08 | 27.4 | In-house | 95-135 (194) | alignment | ||
Range on Protein: 224-265
Range on HMM: 95-135/194.0
KPEEVVPIMELCAHSHsLNSRGNPIIVHCSAGVGRTGTFIAL
| . ...|. . . .. |. . ||| ||.|||||..|
sleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaa
|
|||||||||
| PTEN_1 | 232-264 | 1.6e-07 | 26.3 | In-house | 117-149 (196) | alignment | |||
Range on Protein: 232-264
Range on HMM: 117-149/196.0
MELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIA
. .... .....|| ..||| ||.||.|| .|
cksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 244-325 | 1.8e-07 | 25.3 | In-house | 209-273 (287) | alignment | ||
Range on Protein: 244-325
Range on HMM: 209-273/287.0
RGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNItersrhsDRAteeytrdlieQIVLQLRSQRMKMVQTKDQFLFIYHAA
|..||...|.||.|...|. |.. .| .. | | ..|..|| .| .||. |. ..| |
evGPlvvhddvGiGrsGillatlvlvsrledlGrv.......dva..........avvirlreyraalvqavvqlrllyeal
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 53-152 | 2.1e-07 | 24.7 | In-house | 51-145 (332) | alignment | ||
Range on Protein: 53-152
Range on HMM: 51-145/332.0
D--ARNrYVNIMPYERNRVHLKTLS--GNDYINASYVKVNVPGQSiepgyYIATQGPTRKTWDQFWQMCYHNcplDNIVIVMVTPLVEYNREKCYQYWPR
. || |.|.||.|. |.| . . ||||| .. . |. || | . . |||| . . ||.. || . || .|.|
eavnrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrk.....yiltGiasedkvfafwqmvleq...kspaivqlledvelkleksdkyfpd
GGVD
. .
ktre
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 208-271 | 7.2e-07 | 23.4 | In-house | 121-180 (263) | alignment | ||
Range on Protein: 208-271
Range on HMM: 121-180/263.0
VKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHslNSrgNPIIVHCSAGVGRTGTFIALDHLMHD
..||.|. . .| . | ||. |... || ...||||.|.||. | . .
thtvkhysykgWiekndpelareilnilkvar..ns..kslvvhcstGiGrsaafsvaElvyqk
|
|||||||||
| 0048567 | (Phosphotyrosine protein) phosphatases II | 212-267 | 1e-06 | 23.2 | In-house | 31-99 (157) | alignment | ||
Range on Protein: 212-267
Range on HMM: 31-99/157.0
HH-------FYFDLWKDMNkPEEVVPIMELCAHSHSLNS----RGNPIIVHCSAGV---GRTGTFIALDH
.. .|.|.. | | .. ..... . ... . .|..|.|||.|| |||.|.|..
lyFsiddglvyedfffdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYl
|
|||||||||
| PTPc_motif_SM00404 | 239-271 | 2e-06 | 22.8 | In-house | 74-106 (140) | alignment | |||
Range on Protein: 239-271
Range on HMM: 74-106/140.0
HSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHD
.. ...| ..||| ||| |..|.|. .. .
enaekkggkvlVHCqaGvSRSatliiaYlmryr
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 210-266 | 2.3e-06 | 22.0 | In-house | 159-212 (290) | alignment | ||
Range on Protein: 210-266
Range on HMM: 159-212/290.0
TVHHFYFDLWKDMNKPEEVVPIMELCahsHSLNSRGNPIIVHCSAGVGRTGTFIALD
|| | . |...| .|. ...| . .. .. |.|||| |. | .. |..
tvtHsllkgWnklnvqedtktllsli...qkvkasktpvivHcvdGiSrsAalaaii
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 244-265 | 2.7e-06 | 21.3 | In-house | 225-246 (301) | alignment | ||
Range on Protein: 244-265
Range on HMM: 225-246/301.0
RGNPIIVHCSAGVGRTGTFIAL
| |..||||..|.|.|.....
gggpvvVHCSdtVsrsGvYcsv
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 239-270 | 2.9e-06 | 22.2 | Pfam-A | 67-97 (133) | alignment | ||
Range on Protein: 239-270
Range on HMM: 67-97/133.0
HSLNSRGNPIIVHCSAGVGRTGTFIAlDHLMH
... ..|. ..||| ||. |..|.|. .||
ekaeqkgkkvlVHCqaGisRSatlii.aYlmk
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 239-270 | 2.9e-06 | 22.2 | In-house | 67-97 (133) | alignment | ||
Range on Protein: 239-270
Range on HMM: 67-97/133.0
HSLNSRGNPIIVHCSAGVGRTGTFIAlDHLMH
... ..|. ..||| ||. |..|.|. .||
ekaeqkgkkvlVHCqaGisRSatlii.aYlmk
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 243-299 | 5.4e-06 | 21.0 | In-house | 113-167 (182) | alignment | ||
Range on Protein: 243-299
Range on HMM: 113-167/182.0
SRGnPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRhSDRATEEYTRDLIEQ
..| . ||| || |||| || . .. |. .. . | | |. .||. .|
qeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvr.skrpksiqtreqvel
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 52-120 | 6.8e-06 | 19.9 | In-house | 47-106 (303) | alignment | ||
Range on Protein: 52-120
Range on HMM: 47-106/303.0
NDARNRYVNIMPYERNRVHLktlSGNDYINASYVKVNVPGQSiepgyyIATQGPTRKTWDQFWQMCYHN
| .||.|... . .|.| | || |||.... .. | || | .| .|||| ..
nmdknrfvdvicldhskvkl...sdssyihasyleldsskka......iltqlplshtaadfwqmiieq
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 249-265 | 8e-06 | 20.2 | In-house | 2-18 (69) | alignment | ||
Range on Protein: 249-265
Range on HMM: 2-18/69.0
IVHCSAGVGRTGTFIAL
.||||.| ||||||||.
vvhcssgtgrtgtfiai
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 49-86 | 8.2e-06 | 19.4 | In-house | 44-84 (440) | alignment | ||
Range on Protein: 49-86
Range on HMM: 44-84/440.0
EPRNDARNRYVNIMPYERNRVHLK---TLSGNDYINASYVK
| | .||| ||. |...|| |. . .|||||||..
lpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyin
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