Gene OCA6 in Saccharomyces cerevisiae

Synonym: YDR067C, OCA6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP019_AA protein Get Run
ScerP019_AA_2-162 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Y_phosphatase2 Tyrosine phosphatase family 3-179 8.4e-66 212.8 Pfam-A 1-164 (165) alignment 
Range on Protein: 3-179
Range on HMM: 1-164/165.0
LVTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPEPLSTDPLMvkFCEENNIKTIHIKCQSERKAdktkpkikrkkkTVPIEYDVVVRCVKFL
||.||.||.|...|||.||||..|..||..|.||.|.||.||. |.|.|.  |.||..||..||...|....            .|.|..|......|.|
lvpplnFsaveselyrssyprasnfsflksLkLktiislspeeesqdelq..fleeekiklyhiaiesnkee............lveiksdllkkalkll

IDKGHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSS-INIHERNFIENFNSEIEVDDLDIKDKVPWI
..| .||...||..|.....||..|.||...||..|||||. ....|  .|....|||||.||.||.. ..|.||...
lnkenypvllhckrGkhrtglvigclRklqkWslasilnEyrrFsgskkrivdeefienfdselevekknkklkvlks
subfamily_OCA_pd Subfamily OCA 2-162 1.3e-30 96.8 In-house 143-282 (282) alignment 
Range on Protein: 2-162
Range on HMM: 143-282/282.0
TLVTPLQFSTVQP--------NLYRGSYPREINLPFL-RTLRLKYILSLTPEPLSTDPLMvKFCEENNIKTIHIKCqserkadktkpkikrkkktvpiey
.||.|..||.|.         .|.| ..|.| ||||| ..|.||..|.|..| .... .. .|.....||......                        
slvpprnfslveeykdkpvisgllrlllpeeenlpfLidrlglktaliLdaeeveretia.dflasseiklvslrn........................

dvvvRCVKFLIDKGHYPCYMHCtngELIISLVVACMRKFSYWSTVSILNEFLVYN--SSINIHERNFIENFN
    ...| |.|. .|.....|   .   ..|. ..|| . ....||..|.  ..  .. .......||.|.
....evlkdlldndnyavelsc...qaktdtvlkvLrkdkkygstsiyleyigFtledqeslksillielfd
0051082 (Phosphotyrosine protein) phosphatases II 3-154 5.1e-23 76.8 In-house 2-140 (151) alignment 
Range on Protein: 3-154
Range on HMM: 2-140/151.0
LVTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPEPLSTdpLMVKFCEENNIKTIHIKCQSERKADktkpkikrkkktVPIEYDVVVRCVKFL
|.... || | ..|||...| . .|..|..| .|.|..|..|.      . ....|..|. .|| . .    .            .|. .| |.. ...|
lsdyinfsyvtgglyrsggpladflellkelgiktivnlrseeerg..ycpeylpelgievlhipildwpdpg............lplsfdavleflell

IDKGHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSSINIH-E
.||...|...||. |     ..||....   .|  ..|.|.. ..  . .. .
ldkkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnq
0048179 (Phosphotyrosine protein) phosphatases II 9-160 2.4e-11 39.0 In-house 4-139 (144) alignment 
Range on Protein: 9-160
Range on HMM: 4-139/144.0
FSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPEPlstdplMVKFCEENNIKTIHIKCQSErkadktkpkikrkkkTVPIEYDVVVRCVKFL--IDKG
.| . |.||.||.|  ..|..|. | ......||.|          |.| ..|. .|. .                   ||  .. . ....|.  . . 
pseilpglylgslptaldlellkklgittvinlteey......epefleregiqylhlpwpDh...............gvpdllellleflefieealee

HYPCYMHCTNGELIISLVVAC-MRKFSYWSTVSILNEFLVYNSSINIHE--RNFIEN
..|.. ||. |     ..||. . |   .|  ..|...  ... .....  ..|...
ggpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrpgavpnpgqlrfLle
0048076 (Phosphotyrosine protein) phosphatases II 6-153 4.2e-11 38.2 In-house 1-130 (145) alignment 
Range on Protein: 6-153
Range on HMM: 1-130/145.0
PLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLtpeplstdPLMVKFCEENNIKTIHIKCQSerkadktkpkikrkkKTVPIEYDVVVRCVKFL--I
|  .| . |.||.||.|  ..|..|. | ....|.|          . ...|...|. ... .                  .||  .. . ....|.  .
pywpseilpglylgslptaldlellkdlgittvlnl........tselellerlgiqylylpwpD...............hgvpdllellleflefieea

DKGHYPCYMHCTNGELIISLVVAC-MRKFSYWSTVSILNEFLVYNSSI--NIH
 | ..|.. ||. |     ..||. . .   .|  ..|...  . . .  | .
lkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpgavpnpg
0044763 (Phosphotyrosine protein) phosphatases II 4-117 1.8e-09 33.0 In-house 18-120 (178) alignment 
Range on Protein: 4-117
Range on HMM: 18-120/178.0
VTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPEPLST-DPLMVKFCEENNIKTIHIKCQSERkadktkpkikrkKKTVPIEYDVVVRCVKFL
. .. .| . |.||.||.| . .|..|. | ...|..||.|      ..  ...||..|. .|| .                  ...   . .|. .. .
sdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhg............vpdllehflefvefieea

IDKGHYPCYMHCTNG
.|. . |.. ||. |
ldekggpvlVHCsaG
0051429 (Phosphotyrosine protein) phosphatases II 9-149 1.3e-08 30.3 In-house 16-192 (272) alignment 
Range on Protein: 9-149
Range on HMM: 16-192/272.0
FSTVQPN-LYRGSYP---REINLPFLRTLRLKYILSLTPEPLST----DPLMvkfceeNNIKTIHIKCQSERKADKTKPKIKRKKKTV------------
...| |. |||...|    . ....|..|..|.|..|..|        |..        .|. .|. . ..   . .  ..  .   .            
grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdryw......pgirylhlpilddsaptilygalrvtllseellldyilrell

------------------------PIEYDVVVRCVKFLIDkgHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSS
                        .. .. ... ...| |  ..|...||. |     .|||. .    .|   |....|  |  
ltlllsagearevmhlhytdwpdhgvpqeallellellld..ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
0036282 (Phosphotyrosine protein) phosphatases II 5-146 5.1e-07 25.0 In-house 8-145 (174) alignment 
Range on Protein: 5-146
Range on HMM: 8-145/174.0
TPLQFSTVQPNLYRGSYPREiNLPFLRTLRLKYILSLTPEPLSTDPLMVKFCEEnniktihikcqseR-----KADKTKPKIKRKKKTVPI---EYDVVV
.|| .| . |.|..|..| . ....|. |.......|..|      ..  .. |             .     . . .  ..     .||     ...| 
spldlsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpe.............lredlerlgiqylylpwpDhgvpdlsillefvk

RCVKFLIDKGHYPCYMHCTNGELIISLVVACMRKFSYW--STVSILNEFLVY
.. ..| .... |.. ||. |     ..||...   ..  |.| .|. .   
fveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrel
0041856 (Phosphotyrosine protein) phosphatases II 9-118 1.1e-06 23.8 In-house 19-120 (182) alignment 
Range on Protein: 9-118
Range on HMM: 19-120/182.0
FSTVQPNLYRGSYPR--------------EINLPFLRTLRLKYILSLTpeplsTDPLMVKFCEENNIKTIHIKCQSERKADktkpkikrkkktVPIEYDV
.. . .|||.||.|               . .|..|. |. ..|..||      ..   ...| ..|. ... .      |            ... .| 
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.....eelywpellerlgiqylylpwpDhgvpd............ldelldf

VVRCVKflidkGHYPCYMHCTNGE
. .. .      . |.. ||. | 
ieevle.....eggpvlVHCsaGv