Gene SDP1 in Saccharomyces cerevisiae

Synonym: YIL113W, SDP1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily MSG5
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP035_AA protein Get Run
ScerP035_AA_57-198 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MSG5_pd Subfamily MSG5 35-199 1.4e-102 333.8 In-house 1-165 (165) alignment
Range on Protein: 35-199
Range on HMM: 1-165/165.0
KESPNEDREFVPCSSLDVRRIYPKGPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKRE
|||||||.|.|....|||||.|..|||||||||.||||||..||||.||.|||||.|.|||...||||.|.|..|||||.|..||..||.||||||.||.
kespnedielvhaeildvrrvyldgpllvlpeklylysepklkellsfdlvinvakeindlellvpavkyyhiewehdskivkdlsrltriihaatskrk

KILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTN
|||.||||||||||.||.||||||.|||||..||.|||.||.|.||||||||||||||||..|.|
kilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewevalskksn

DSPc Dual specificity phosphatase, catalytic domain 68-191 1.2e-37 123.7 Pfam-A 1-131 (133) alignment
Range on Protein: 68-191
Range on HMM: 1-131/133.0
IYLYSEPTVK----ELLPFDVVINVAEEAN---------DLRMQVPaVEYhhyrwEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAY
.||.|..| .    | | ...||||..| .           ....| ||      |....|. .|......|..|..|..|.|.|||.|.||||||||||
lylgskstaslalleklgitlvinvtkevpnnnaikkseieylrip.ved.....etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaY

IMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE
.||..||||.. |...|.|..||.|..|...||.|.|
lmktknlslneAyefvkerrskispnagflrqLleye

DSPc Dual specificity phosphatase, catalytic domain 68-191 1.2e-37 123.7 In-house 1-131 (133) alignment
Range on Protein: 68-191
Range on HMM: 1-131/133.0
IYLYSEPTVK----ELLPFDVVINVAEEAN---------DLRMQVPaVEYhhyrwEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAY
.||.|..| .    | | ...||||..| .           ....| ||      |....|. .|......|..|..|..|.|.|||.|.||||||||||
lylgskstaslalleklgitlvinvtkevpnnnaikkseieylrip.ved.....etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaY

IMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE
.||..||||.. |...|.|..||.|..|...||.|.|
lmktknlslneAyefvkerrskispnagflrqLleye

PTPc_motif_SM00404 63-191 1.3e-34 114.0 In-house 5-138 (140) alignment
Range on Protein: 63-191
Range on HMM: 5-138/140.0
VLPEkIYLYSEPTVK-----ELLPFDVVINVAEEAN-------DLRMQVPaVEYhhyrwEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATL
.||. .||.|... .     . | ...||||.|| .         ..|.| ..      .. .... .|......|..|..|..|.|.|||.|.||||||
ilph.lylgskskaqnpallkklgithvinvteevsltkensgfqilqip.ldd.....nekdklskyldkvldfienaekkggkvlVHCqaGvSRSatl

IIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE
||||.|.|..|||...|...|.|...|.|......||.|.|
iiaYlmryrqlslaeayefvkerRpiispnlnfvrqLieye

0044763 (Phosphotyrosine protein) phosphatases II 41-197 4.1e-27 90.4 In-house 4-173 (178) alignment
Range on Protein: 41-197
Range on HMM: 4-173/178.0
DREFVPCSSLDVRRIYPKGPLLVLPEkIYLYSEPTVKEL-----LPFDVVINVAEEANDLRMQVPA-------VEYHHYRW--EHDSQIALDLPSLTSII
.  .. ..  .. |... ..  .||  .|| | |... |     | .....|..||    ... ..       ..|.|. .   .. ..   .. .. .|
rtrvllsnleglersdyinaseilpg.lylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefi

HAAT-TKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADkINPSIGLIFQLMEWEVALNAK
..|  .| ...|.||..|..||.||..||.||...||| . ..|...|   |.|. | . ||.|.|  |...
eealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllke

subfamily_DSP14_pd Subfamily DSP14 84-202 3.6e-24 79.5 In-house 34-152 (157) alignment
Range on Protein: 84-202
Range on HMM: 34-152/157.0
VVINVAEEANDlrMQVPAVEYHHYRW--EHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSI
..|||. |...   ... .|. . .   ......|  .   .  |.....|  |.|.||  | ||||.| .||.|||..||||..| |.||.   |.| .
liinvtvelpn..tklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRpiirPNv

GLIFQLMEWEVALNAKTNVQA
|   ||...| .|..|. |. 
GFwkqlidyEkklkgkssvkm

subfamily_DSP1_pd Subfamily DSP1 84-198 8.9e-23 75.2 In-house 46-160 (163) alignment
Range on Protein: 84-198
Range on HMM: 46-160/163.0
VVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGL
 ..||..| ..   ..   .  . . ... .| | .      |.....|. |.||||| |.|||.||..||.|| ...||   .|. |.|   |.| .| 
ailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRsiisPnagF

IFQLMEWEVALNAKT
. ||...|  | ...
vlqLlnyekklllel

0048179 (Phosphotyrosine protein) phosphatases II 60-191 1.1e-22 75.8 In-house 4-141 (144) alignment
Range on Protein: 60-191
Range on HMM: 4-141/144.0
PLLVLPEkIYLYSEPTVKELLP-----FDVVINVAEEANDLRMQVPAVEYHHYRWEHDS--QIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLII
|  .||  .|| | ||...|       .. |||..||     . .. ..|.|. |.  .  ... .|...  .|..|  . ...|.||..|..|..||..
pseilpg.lylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlva

AYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE
||.||...||| . ..|..||   ..|. | . .|.|.|
aylmkklglsleealalvrsrrpgavpnpgqlrfLleye

0041856 (Phosphotyrosine protein) phosphatases II 66-198 2.1e-22 75.0 In-house 24-176 (182) alignment
Range on Protein: 66-198
Range on HMM: 24-176/182.0
EKIYLYSEPT--------------------VKELlPFDVVINVAEEANDLRMQVPAV-EYHHYRWEHDSQIAldLPSLTSIIHAATTKREKILIHCQCGL
...|| | |.                    .|||  . ...|..||  .      .. .|... |. ..     |..| ..|...  . ...|.|| .|.
anlylgslpatrfiatqgpllstvadflrmlkel.gittivnlteelywpellerlgiqylylpwpDhgvpd..ldelldfieevleeggpvlVHCsaGv

SRSATLIIAYIMKYHNLSLRHSYDLLKSRAD--KINPSIGLIFQLMEWEVALNAKT
.|..||..||.||....||.. ..|..||     |.|. . . ||...|. |. ||
gRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllkkt

subfamily_DSP6_pd Subfamily DSP6 83-196 4e-22 72.4 In-house 41-156 (158) alignment
Range on Protein: 83-196
Range on HMM: 41-156/158.0
DVVINVAEEANDLRMQVPAVEYHHYRWE--HDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPS
  |.||... ..   . . ..| .   |  .  ..|  .|   . |  | .| .|.|.||  |.||| |...||.||...||| ..|||.|.|  .| | 
kyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksnisPn

IGLIFQLMEWEVALNA
  .. ||...|  |. 
fnfmgqlldferslrl

0049772 (Phosphotyrosine protein) phosphatases II 55-196 4.5e-22 74.6 In-house 124-275 (314) alignment
Range on Protein: 55-196
Range on HMM: 124-275/314.0
IYP------------------KGPLLVLPEKIylySEPTVKELLPFDvvinvaEEANDLRMQVPA-VEYHHYRWEHDSQ-IALDLPSLTSIIHAAtTKRE
|..                  | ||| |...    .|||...|  .       || .|      . ..|... .. .|. .  |....  .|..|  | .
ivmsrdevladelsrLdaAlgKtpllildgng...neptaadlellk......eelydpelferlgikylripvpDgsaplledfdeflefieea.dkgg

KILIHCQCGLSRSAT-LIIAYIMKYHNLSLRHSYDLLKSRADkINPSIGLIFQLMEWEVALNA
..|.||. | .|..| ...||.||....||.  .. ....   |||. |.| ||...|  |.|
pvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyefilea

0048076 (Phosphotyrosine protein) phosphatases II 60-194 1.2e-21 72.3 In-house 4-142 (145) alignment
Range on Protein: 60-194
Range on HMM: 4-142/145.0
PLLVLPEkIYLYSEPTVKELL-----PFDVVINVAEEANDLRMQVPavEYHHYRWE--HDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLII
|  .||  .|| | ||...|       .  |.|.. | ..|  ..   .|... |.  .  ... .|...  .|..|  . ...|.||. |..|..||..
pseilpg.lylgslptaldlellkdlgittvlnltselellerlgi..qylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlva

AYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVAL
||.|.....|| . ..|..|.  ...|. | . .|.|.|  |
aylmlllgvsleealelvrsqrpgavpnpgqlrflyefelel

subfamily_DSP10_pd Subfamily DSP10 83-197 2.9e-21 70.0 In-house 41-156 (159) alignment
Range on Protein: 83-197
Range on HMM: 41-156/159.0
DVVINVAEEANDLRMQvPAVEYHHYRWEHDSQI--ALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPS
..|.||. .      .  |..|..   .  |..            |. |  | ...|.||| |.|||||..|||.||. ||||...|.. |..   | | 
tavlnvttsvPnefee.ealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrpiisPn

IGLIFQLMEWEVALNAK
.. . ||.|.|  || .
LnfmGqLlefekelnks

subfamily_DSP12_pd Subfamily DSP12 116-206 1e-20 68.7 In-house 65-154 (155) alignment
Range on Protein: 116-206
Range on HMM: 65-154/155.0
ALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAkTNVQANSYR
   |.. .. |. |  .....|.||| |.|||.|..|||.||...||| . ..|.|.   .|.|  | . ||  .|       . . ..|.
LshldeavdFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeiepNegFleQLklfekmgck.vdtsnkayk

subfamily_STYXL1_pd Subfamily STYXL1 59-195 1.2e-20 67.4 In-house 10-154 (157) alignment
Range on Protein: 59-195
Range on HMM: 10-154/157.0
GPLLVLPEKIYLY-----SEPTVKELLPFDVVINVAEEANDLRMQVPA-VEYHHYRWEHD--SQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATL
 |  |||.|.||       .|..|. |    ..||. .|..|   |.  ..  | . | .  ...   |  . . |.   .. | .|.  . |.||||..
yPvevlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaav

IIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALN
||||.| .....|...|. ||   . ..|  ... || |||  | 
iiaylmyskkitlkkaykylkkCkenvkPnrafveqlseWekqll

subfamily_DSP8_pd Subfamily DSP8 112-198 1.2e-20 67.7 In-house 72-158 (159) alignment
Range on Protein: 112-198
Range on HMM: 72-158/159.0
DSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKT
| ..   ... .. |  | ..  ..|.|.  | |||||..||||||. ..|| ..|  .|..   |.|..  . ||.|.|  |. .|
dekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekrptispnlnflgqLleyekelkllt

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 84-192 1e-19 64.5 In-house 37-145 (148) alignment
Range on Protein: 84-192
Range on HMM: 37-145/148.0
VVINVAEEANDLRMQvpAVEYHHYRWEHDSQIAL--DLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSI
.|   .|  | |  .  ..|| | . . . . .|    ..... .. |  . ...|.|.| | |||. | ......... ||.. ..| ||.   ..|  
ivnatkerdnaldqr..gieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrvslkealalvkskrryvdpnl

GLIFQLMEWEV
| . || |.| 
gfLkqLaeleq

0046846 (Phosphotyrosine protein) phosphatases II 56-194 2.3e-18 62.0 In-house 7-172 (176) alignment
Range on Protein: 56-194
Range on HMM: 7-172/176.0
YPKGPLLVLPEKIYLYSEP----------------TVKELlPFDVVINVAEEANDLRMQVPA---------VEYHHYRWE-HDSQIALDLPSLTSIIHAA
.. ..|  ......| | |                 .|||  ...|.|. ||    | ..|          ..|.|. |. |.     .|..|  .|. |
gldldldyinanlilgsrpiatqgplprtladflemlkel.gitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefirea

TTKREKILIHCQCGLSRSATLIIAYIMKY-HNLSLRHSYDLLKSRAD-KINPSIGLIFQLMEWEVAL
 .. ...|.||. |..|..||..||.... ..||. . ..|....   .. .. . . .|.|.|  |
lkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll

subfamily_Slingshot_pd Subfamily Slingshot 84-201 2.5e-18 60.0 In-house 47-164 (169) alignment
Range on Protein: 84-201
Range on HMM: 47-164/169.0
VVINVAEEANDLRMQvpAVEYHHYRW--EHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSI
 ..||..| ..   .   .||.. |   |.....     .  . |..| .|  |.|.||. |.||||. .||| || ..||| .... .|.| . |.|  
yilnvtkeidnffpe..kfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerrsvikPnk

GLIFQLMEWEVALNAKTNVQ
|.. || |.|  |.|. . .
gflkqleeyeGileaskqrh

subfamily_DSP15_pd Subfamily DSP15 85-198 4.2e-18 59.9 In-house 31-143 (151) alignment
Range on Protein: 85-198
Range on HMM: 31-143/151.0
VINVAEEANDLRMQvpaVEYHHYRWEHDSQIALD--LPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIG
...| ..|. |. .   .||. .. .  ..  |.  .    ..||..  | |..|.||  |.|||.||..||.|   .|. | . . .| .    || .|
ilsvhdnakkllkd...ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaRsvanPnfG

LIFQLMEWEVALNAKT
   ||.|.| .  .. 
fkrqlkeyektklkey

subfamily_DSP19_pd Subfamily DSP19 110-194 6e-18 59.6 In-house 66-150 (152) alignment
Range on Protein: 110-194
Range on HMM: 66-150/152.0
EHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVAL
. . ..   |.. .  |. | .|   .|.||. | ||||...|||.|| ..|||.....|...    |.|  | | || |.|  |
lpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpcikPneGFikqLkeyeael

0043147 (Phosphotyrosine protein) phosphatases II 83-194 1.8e-17 59.1 In-house 46-160 (172) alignment
Range on Protein: 83-194
Range on HMM: 46-160/172.0
DVVINVAEEANDLRMQVPA-VEYHHYRWE-HDSQIALDLPSLTSIIHA--ATTKREKILIHCQCGLSRSATLIIAYIMKyHNLSLRHSYDLLKSRADKIN
....|. |. .|    ..  ..|... |. |. ...  |... ..|.   |  . ...|.||  |..|..||..||.|. ..||| . ..|....  .. 
thivnltellydpellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgav

PSIGLIFQLMEWEVAL
.. . . .|...|  |
qnpsqyrflyyfekll

0045098 (Phosphotyrosine protein) phosphatases II 84-194 2.3e-17 58.8 In-house 91-271 (278) alignment
Range on Protein: 84-194
Range on HMM: 91-271/278.0
VVINVAEEAND-----------------------------------------------LRMQVPAVEYHHY-RWEH----DSQIALDLPSLTSIIHAATT
|.....|.  .                                                  .   |...||  |.     .. |   . .|.  |..|  
vivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealk

--------------KREKILIHCQCGLSRSATLIIAYIMKYH---NLSLRHSYDLLKSRADK-INPSIGLIFQLMEWEVAL
              . ...|.||. |..|..||..||.|...   ...| . .. |.|.    . .. . . .|.|... |
llaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel

subfamily_LRR-DSP_pd Subfamily LRR-DSP 132-195 2.4e-17 56.9 In-house 196-259 (263) alignment
Range on Protein: 132-195
Range on HMM: 196-259/263.0
KREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALN
|.  .|.||. |.|||.||.|.|.||...| .....|| ...  .|.| .|.. ||. .|  | 
kkGGvlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklf

0037934 (Phosphotyrosine protein) phosphatases II 55-192 4.1e-17 58.0 In-house 33-239 (243) alignment
Range on Protein: 55-192
Range on HMM: 33-239/243.0
IYPKGPLLVLPEKIYLYSEPTVKELLP-------------FDVVINVAEEA------------------------------------------ND-LRMQ
 |  . |   ...... . |. . .               ..|.... |.                                            |    .
dyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddlt

VPAVEYHHYRWEH----D--SQIALDLPSLTSIIHA-----ATTKREKILIHCQCGLSRSATLIIAYIMKYH-NLSLRHSYDLLKSRADK-INPSIGLIF
   . ||.. | .    |  ...   |  ....|..     |  . ...|.||  |..|..|||.||.|... ...| . ..||...    . .. . . 
rlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyr

QLMEWEV
.|.|.. 
flyeall

0045450 (Phosphotyrosine protein) phosphatases II 102-192 3.3e-16 55.4 In-house 198-301 (307) alignment
Range on Protein: 102-192
Range on HMM: 198-301/307.0
VEYHHYRWEhDSQIALDLPSLTSIIHAATT------KREKILIHCQCGLSRSATLIIAYIMKYHN--------LSLRHSYDLLKSRADKINPSIGLIFQL
  .|...|  | ..  .. .| ..|... .      | ...|.||  |..|..|.|.||.|...         ..|.. ..||...  .. .. . . .|
thfhytgwp.dhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfl

MEWEV
.|.. 
yeall

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 127-192 6.8e-16 52.0 In-house 83-150 (154) alignment
Range on Protein: 127-192
Range on HMM: 83-150/154.0
HAAT--TKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEV
. |    ...|.|.|.. |.||||.|.|.|.|.  ..||  .. |||.   .|.|  |.. ||  .| 
ddaiggvennkvlvhsdkGvsrsaallisylmdklkislslalellkdsryiikPnqGflkqleifek

subfamily_DSP3_pd Subfamily DSP3 125-196 9.6e-16 51.8 In-house 89-159 (162) alignment
Range on Protein: 125-196
Range on HMM: 89-159/162.0
IIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRAdKINPSIGLIFQLMEWEVALNA
| .| ..|. |.|.||. |.||||||..||.| .....| .     ...  .| |  | . ||.| .  |. 
idealsqkegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkkR.eilPneGFlkqLaeldeelkr

PTEN_1 35-189 1e-15 53.1 In-house 10-186 (196) alignment
Range on Protein: 35-189
Range on HMM: 10-186/196.0
KESPNEDREFVPCSSLDVRRI----YPKGPLLV-LPEKIYLYSEPTVKEL------LPFDVVINVAEEAND------LR-MQVPAVEYHHYRWEHDS--Q
|. . .. |.. ...   |.|     |  |||  ..|. |. |.. | ..        .  |.|..|| ..      |.  .   |||.|. .| .    
kknlalptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgaps

IALDLPSLTSIIHAATT--KREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLME
..  .  . |.|...    .....|.||. ||.||.|...|| |....|. .   .|....  ...| ..   .|.|
lselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlle

0049260 (Phosphotyrosine protein) phosphatases II 84-191 1.7e-15 52.5 In-house 36-146 (152) alignment
Range on Protein: 84-191
Range on HMM: 36-146/152.0
VVINVAEEANDLRMQVPA-VEYHHYRWEHDS--QIALDLPSLTSIIHA-ATTKREKILIHCQCGLSRSATLIIAYIMKyHNLSLRHSYDLLKSRADKINP
..... |.  . . ...   .|.|. |. ..  ...  |. |  .|.  |  | ...|.||  |..|..||..||.|. ...|| . ..|....  ...|
tivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekRpgavp

SIGLIFQLMEWE
. | ...|.|.|
npgqlrflyefe

subfamily_STYX_pd Subfamily STYX 118-201 1.7e-15 50.5 In-house 81-164 (166) alignment
Range on Protein: 118-201
Range on HMM: 81-164/166.0
DLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTNVQ
 ||   ..|  .  |  |.|.| ..|.||||.|.|||||. . |  |...  .. |   |||  |.. ||.|.|.   || ...
ylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylakltik

0040439 (Phosphotyrosine protein) phosphatases II 103-191 2.9e-15 52.0 In-house 144-242 (249) alignment
Range on Protein: 103-191
Range on HMM: 144-242/249.0
EYHHYRWEhDSQIALDLPSLTSIIHAATT------KREKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE
 .... |  | ..  ....| ..|.|. .      | ...|.||  |..|..|.|.||.|     |.....| . ..||.|.  .. .. . . .|.|..
hiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeal





subfamily_MKPLT_pd Subfamily MKPLT 61-192 4.5e-15 49.6 In-house 22-158 (164) alignment
Range on Protein: 61-192
Range on HMM: 22-158/164.0
LLVLPEKIYLYS-----EPTVKELLPFDVVINVAEEANDLRMQvpAVEYHHYRWEHDS--QIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIA
 .||....||       . .| . |  . ..||..| .|   .  .|||   . |  |  |..  |  ..  .  |     ..|.||. | |||..  .|
svvledtlylGnakhatnekvlkdlkithivnvsqekkdafpk..sveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtva

YIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEV
...|..   |...|. || |   ..|  |.. || ..| 
fLikskgwtlkeayeylkerrsivapnrGflkqlakfee

subfamily_MKPLV_pd Subfamily MKPLV 61-192 4.5e-15 49.6 In-house 22-158 (164) alignment
Range on Protein: 61-192
Range on HMM: 22-158/164.0
LLVLPEKIYLYS-----EPTVKELLPFDVVINVAEEANDLRMQvpAVEYHHYRWEHDS--QIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIA
 .||....||       . .| . |  . ..||..| .|   .  .|||   . |  |  |..  |  ..  .  |     ..|.||. | |||..  .|
svvledtlylGnakhatnekvlkdlkithivnvsqekkdafpk..sveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtva

YIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEV
...|..   |...|. || |   ..|  |.. || ..| 
fLikskgwtlkeayeylkerrsivapnrGflkqlakfee

0042113 (Phosphotyrosine protein) phosphatases II 94-191 9e-15 50.2 In-house 133-239 (245) alignment
Range on Protein: 94-191
Range on HMM: 133-239/245.0
DLRMQVPAVEYHHYRWEhDSQIALDLPSLTSIIHAATT-----KREKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRHSYDLLKSRADKINPSIGL
    .   . ||.. |. | ... .| .| ...... .     . ...|.||  |..|..|.|.||.|     |....|| . .. |.|.  .. .. . 
gddesrevihyhylpwp.dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsq

IFQLMEWE
. .|.|..
yrflyeal

0039614 (Phosphotyrosine protein) phosphatases II 104-193 9.5e-15 50.3 In-house 188-287 (297) alignment
Range on Protein: 104-193
Range on HMM: 188-287/297.0
YHHYRWEhDSQIALDLPSLTSIIHAATT------KREKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEV
.... |  | ..  .| .| ...... .      | ...|.||  |..|..|.|.||.|     |...... . .. |...  .. .. . . .|.....
fqytgwp.dhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydall

A
 
e

0036282 (Phosphotyrosine protein) phosphatases II 97-193 5.4e-14 47.7 In-house 65-168 (174) alignment
Range on Protein: 97-193
Range on HMM: 65-168/174.0
MQVPAVEYHHYRWEHDSQIALD-LPSLTSIIHAATTK--REKILIHCQCGLSRSATLIIAYIMKYHNL-SLRHSYDLLKSRA---DKINPSIGLIFQLME
.    ..|... |. ..   |. | .. .... |  .    ..|.||  |..|..||..||.|... | ||.. .||....     .. .. . . .| .
lerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyy

WEVA
.|  
fekl

0040438 (Phosphotyrosine protein) phosphatases II 103-193 2.6e-13 45.4 In-house 175-274 (317) alignment
Range on Protein: 103-193
Range on HMM: 175-274/317.0
EYHHYRWEHDSQIALDLPSLTSIIHAATTK----REKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVA
  .|| .  |  .  .. .| ....|. ..     ...|.||  |..|..|.|.||.|     |...... . .. |...  .. .. . . .|....  
thfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalle





0051082 (Phosphotyrosine protein) phosphatases II 82-190 5.1e-13 44.4 In-house 34-149 (151) alignment
Range on Protein: 82-190
Range on HMM: 34-149/151.0
FDVVINVAEEA--NDLRMQVP--AVEYHHYRWEHDS--QIALDLPSLTSIIHAATTK-REKILIHCQCGLSRSATLIIAYIMKyHNLSLRHSYDLLKSRA
.....|. .|   . .   .|   .|..|. .. ..  .. | .... ......  |   ..|.||  |..|..||...|.|. ...||   .. .... 
iktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkr

D-KINPSIGLIFQLMEW
  ...|. . .|||...
pgvvqpnqqflfqlfal

0036941 (Phosphotyrosine protein) phosphatases II 103-199 7.1e-13 44.0 In-house 171-281 (297) alignment
Range on Protein: 103-199
Range on HMM: 171-281/297.0
EYHHYRWEHDSQIALDLPSLTSIIHAATT------KREKILIHCQCGLSRSATLIIAYIM--------KYHNLSLRHSYDLLKSRADKINPSIGLIFQLM
 ..||    |  .  .  || ..|... .      . ...|.||  |..||.|.|.|..|        |......   .  |...   . .. .   .| 
thfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrfly

EWEVALNAKTN
|..  |  |..
eallellkkkl

0043336 (Phosphotyrosine protein) phosphatases II 102-190 1.6e-12 43.0 In-house 176-272 (278) alignment
Range on Protein: 102-190
Range on HMM: 176-272/278.0
VEYHHYRWEhDSQIALDLPSLTSIIHAATT----KREKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEW
. ||.. |  | ..  .| .| ....|. .    . ...|.||  |..|..|.|..|..     |.....| . .. |...  .. ..   . .| |.
thyhylgwp.dhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyea

0038934 (Phosphotyrosine protein) phosphatases II 104-181 5.8e-12 41.1 In-house 80-163 (194) alignment
Range on Protein: 104-181
Range on HMM: 80-163/194.0
YHHYRWEH-DSQIALDLPSLTSIIHAATTKR-----EKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSI
......   |   . .|  |....... ..      .....||  ||.|..||..||.......|.. ...|....  .. |..
ieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnq

subfamily_PTPMT1_pd Subfamily PTPMT1 124-178 7.1e-11 36.8 In-house 98-152 (171) alignment
Range on Protein: 124-178
Range on HMM: 98-152/171.0
SIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKIN
 .|.  ..| ... .||. | .|||||...|.|| ..||. .  . ||.. ..|.
efiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiir

0051429 (Phosphotyrosine protein) phosphatases II 85-194 1.1e-10 37.2 In-house 49-224 (272) alignment
Range on Protein: 85-194
Range on HMM: 49-224/272.0
VINVAEEA----NDLRMQVPAVEYHHYRWEHDSQIALD----------------------------------------------------LpsLTSIIHA
.... .|     ..  .  | ..|.|. .. ||                                                            | .....
ivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellel

ATTkREKILIHCQCGLSRSATLIIAYIMKyHNLS--------------LRHSYDLLKSRADKINPSIGLIFQLMEWEVAL
  .  ...|.||  | .|..|.. ....  ...|              |.. .. |...  ..... . . .|.|....|
lld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallel

0047943 (Phosphotyrosine protein) phosphatases II 103-170 3.1e-10 35.4 In-house 170-247 (273) alignment
Range on Protein: 103-170
Range on HMM: 170-247/273.0
EYHHYRWEhDSQIALDLPSLTSIIHAATT------KREKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRHSYDLL
 .|.. |  | ..  .| || ..|... .      . .....||  |..|..|.|.....     |......   . ||
hfhytgwp.dhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkll

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 123-195 1.9e-09 30.8 In-house 70-142 (145) alignment
Range on Protein: 123-195
Range on HMM: 70-142/145.0
TSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALN
| .|     .   ...||  |.||| |. .|..||| |..| ..   ..|.  .  | . .. .|.. |  | 
tdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrllaypnvtflknllnlekqlk

0046845 (Phosphotyrosine protein) phosphatases II 103-163 5.2e-09 31.4 In-house 169-242 (284) alignment
Range on Protein: 103-163
Range on HMM: 169-242/284.0
EYHHYRWEhDSQIALDLPSLTSIIHAATTK------REKILIHCQCGLSRSATLIIAYIMKYH--------NLSL
 .|.  |  | ..  .. .| ...... .        ..|..||  |..|..|.|........        ....
hfhytswp.dhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdv

0051299 (Phosphotyrosine protein) phosphatases II 103-165 1e-08 30.5 In-house 186-256 (288) alignment
Range on Protein: 103-165
Range on HMM: 186-256/288.0
EYHHYRWEhDSQIALDLPSLTSIIHAATTK----REKILIHCQCGLSRSATLIIAYIM-----KYHNLSLRH
 .|.. |  | ..  .. .| ...... ..       ...||  |..|..|.|.....     | . ... .
hfhytnwp.dhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvle

0050432 (Phosphotyrosine protein) phosphatases II 104-164 3.8e-08 28.5 In-house 202-268 (308) alignment
Range on Protein: 104-164
Range on HMM: 202-268/308.0
YHHYRWEhDSQIALDLPSLTSIIHAATTK--REKILIHCQCGLSRSATLIIAYIM-----KYHNLSLR
.|.  |. | ..  .. .| ...... ..   ..|..||  |..|..|.|.....     | ..... 
fhytnWp.dhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvf

PTPc_DSPc_SM00012 103-161 1e-07 27.4 In-house 4-67 (105) alignment
Range on Protein: 103-161
Range on HMM: 4-67/105.0
EYHHYRWEHDsQIALDLPSLTSIIHAATTKRE------KILIHCQCGLSRSATLIIAYIMKYHNL
 ||.. | .  ..  .  |......|  ....       ...||. | .|..|.. ..|.  .. 
hyhytgwpdh.gvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqle

0048567 (Phosphotyrosine protein) phosphatases II 122-171 1.3e-07 26.1 In-house 63-115 (157) alignment
Range on Protein: 122-171
Range on HMM: 63-115/157.0
LTSIIHAATTKREKILIHCQCGL---SRSATLIIAYIMKYHNLSLRHSYDLLK
| ....  . .. .| .||  ||   .|.|||| .|........ .  ...|.
lnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplr

subfamily_Dicty-DSP-Subfam1_pd Subfamily Dicty-DSP-Subfam1 108-167 2.4e-07 23.5 In-house 42-100 (128) alignment
Range on Protein: 108-167
Range on HMM: 42-100/128.0
RWEHDsQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSY
 |..| ..   ..    |. .       . .||.||  |.  .. .|.|||.  .|... 
dwsad.klpyrirdyrnillserelplvlyvhcecgcdrtgevlasyvmkykgydlkkal

subfamily_Dicty-DSP19-1_pd Subfamily Dicty-DSP19-1 108-167 2.5e-07 23.5 In-house 41-99 (128) alignment
Range on Protein: 108-167
Range on HMM: 41-99/128.0
RWEHDsQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSY
 |..| ..   ..    |. .       . .||.||  |.  .. .|.|||.  .|... 
dwsad.klpyrirdyrnillserelplvlyvhcecgcdrtgevlasyvmkykgydlkkal

subfamily_CDC14_pd Subfamily CDC14 124-162 8e-07 23.2 In-house 254-292 (328) alignment
Range on Protein: 124-162
Range on HMM: 254-292/328.0
SIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLS
. ...| . . .| .||. || |  ||| .|.|| ....
kfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrft

Y_phosphatase Protein-tyrosine phosphatase 102-157 1.3e-06 23.4 Pfam-A 136-194 (235) alignment
Range on Protein: 102-157
Range on HMM: 136-194/235.0
VEYHHYRWEhDSQIALDLPSLTSIIHAATTKR----EKILIHCQCGLSRSATLIIAYIMK
 ..|.  |. |...  .  ||...|..  ...    .....||  | .|..|.. . |. 
kqlhytnWp.dhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill

Y_phosphatase Protein-tyrosine phosphatase 102-157 1.3e-06 23.4 In-house 136-194 (235) alignment
Range on Protein: 102-157
Range on HMM: 136-194/235.0
VEYHHYRWEhDSQIALDLPSLTSIIHAATTKR----EKILIHCQCGLSRSATLIIAYIMK
 ..|.  |. |...  .  ||...|..  ...    .....||  | .|..|.. . |. 
kqlhytnWp.dhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill

DSPc_SM00195 101-156 1.5e-06 23.1 In-house 160-218 (263) alignment
Range on Protein: 101-156
Range on HMM: 160-218/263.0
AVEYHHYRWEHDsQIALDLPSLTSIIHAATTKRE----KILIHCQCGLSRSATLIIAYIM
.  |..  |..  ..  .  |......|......     |..||. |..|..|.. . |.
vtqyqyknWpdh.gvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii

PTPc_SM00194 101-156 1.5e-06 23.1 In-house 160-218 (263) alignment
Range on Protein: 101-156
Range on HMM: 160-218/263.0
AVEYHHYRWEHDsQIALDLPSLTSIIHAATTKRE----KILIHCQCGLSRSATLIIAYIM
.  |..  |..  ..  .  |......|......     |..||. |..|..|.. . |.
vtqyqyknWpdh.gvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidii

subfamily_PTPDC1_pd Subfamily PTPDC1 120-196 1.8e-06 22.5 In-house 102-177 (182) alignment
Range on Protein: 120-196
Range on HMM: 102-177/182.0
PSLTSIIHAATTKReKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNA
  .  ... | ..  |. .||  || |   || .|..  ..|.  .. .|..|.  |   . . .  . |..  |  
Ldivkvvafalqeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefalflip

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 75-156 3.3e-06 21.3 In-house 151-233 (307) alignment
Range on Protein: 75-156
Range on HMM: 151-233/307.0
TVKELLPFDVVINVAEEANDLRMQvpAVEYHHYRWEHDSQIALDLPSLTSI--IHAATTKREKILIHCQCGLSRSATLI-IAYIM
 .|.| | . .|||..   |   .  .   .|..||   .       ||.|  ..|   ... ...||  |. || |.. |....
gakklapdedlinvttlkvdwaqk..srtiqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivaislvq

Init_tRNA_PT Initiator tRNA phosphoribosyl transferase 81-182 4e-06 17.1 Pfam-A 318-427 (451) alignment
Range on Protein: 81-182
Range on HMM: 318-427/451.0
PFDVVINVAEEANDLRMQVPAVEYHHYRWEHD----SQIALDLPSLTSIIHAATTK--REKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKS--
 .|.||.. |.      .  . ...... |..     ..  .||.....|.. ...   .|||..|. |   |.....| . .|.... . .    ..  
evdlvislsekivsseteekkkkvlelklesskkgskeLrkalpkieefiksklsseknkkilvlcesGkdlsvgvvlailclyfdeegklkkseeekki

RADKINPSIG
  . |   . 
nkelirkrla

subfamily_DSP23_pd Subfamily DSP23 88-163 8.4e-06 20.5 In-house 38-114 (148) alignment
Range on Protein: 88-163
Range on HMM: 38-114/148.0
VAEEANDLRMQVPAVEYHHYRWEHDSQIALD-LPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSL
..||..     .|.. ... | .     ||. .  .  ... |  | | . .||  |  |. |..  |..| ..|. 
lteegrphveatpnltlvrlriddyhppaleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaa