Gene SIW14 in Saccharomyces cerevisiae

Synonym: OCA3, YNL032W, SIW14

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP055_AA protein Get Run
ScerP055_AA_104-264 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Y_phosphatase2 Tyrosine phosphatase family 116-276 1.3e-70 228.4 Pfam-A 1-161 (165) alignment 
Range on Protein: 116-276
Range on HMM: 1-161/165.0
VIPPENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCN
..||.|||.|. |.||||.||..|||||.. ||||.|..|.|||..|..|.||. . ||||.. ...|||..|.|.|.||.|||...|| .|.|.|.||.
lvpplnFsaveselyrssyprasnfsflks.LkLktiislspeeesqdelqfleeekiklyhiaiesnkeelveiksdllkkalklllnkenypvllhck

RGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYDDDEIKRIAS-KNNW
|||||||..|||.||||.|||..|..|||||. .|.|..|..|||..|.. ... .. |...
rGkhrtglvigclRklqkWslasilnEyrrFsgskkrivdeefienfdselevekknkklkv
subfamily_OCA_pd Subfamily OCA 104-263 1e-36 116.8 In-house 132-282 (282) alignment 
Range on Protein: 104-263
Range on HMM: 132-282/282.0
VMNTLNHVINKEVIPPENFSHVVG--------EIYRSSFPRQENFSFLHERLKLKSILVLIPEEYPQENL-NFLKLTGIKLYQVGMsgnkepfvnipshl
...|.... .....||.|||.|          ...|.. |..||..||..||.||..|.| .||...|.. .||. . |||... .              
ifgthffprlyslvpprnfslveeykdkpvisgllrlllpeeenlpfLidrlglktaliLdaeeveretiadflasseiklvslrn..............

ltKALEIVLNPANQPILIHCnrgKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAF-PKARALDQQFIEMYD
  ..|...|.  | .....|   ...|.......||......|.|..||..|.   ...  ....||..|
..evlkdlldndnyavelsc...qaktdtvlkvLrkdkkygstsiyleyigFtledqeslksillielfd
0051082 (Phosphotyrosine protein) phosphatases II 116-263 2.7e-35 116.6 In-house 2-148 (151) alignment 
Range on Protein: 116-263
Range on HMM: 2-148/151.0
VIPPENFSHVVGEIYRSSFPRQENFSFLhERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCN
. .. ||| | | .|||..| .... .| ..|..|.|. | .||... . ..|. .||..... . ....| . .  . . ..||..|.. |.|.|.||.
lsdyinfsyvtgglyrsggpladflell.kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCs

RGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYD
 ||.|||.|......|...||  ...|||.. . . .  .|.......
aGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnqqflfqlfa
0051429 (Phosphotyrosine protein) phosphatases II 108-256 2e-27 91.9 In-house 3-199 (272) alignment 
Range on Protein: 108-256
Range on HMM: 3-199/272.0
LNHVINKEVIPPENFSHVVGEIYRSSFP---RQENFSFLhERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVN---------------
|...||   ..  .   . | .|||..|    ...| .| ..|..|.|. | .||. . .  .. . ||..... . .. .|...               
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll

---------------------------------IPSHLLTKALEIVLNpaNQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQ
                                 .|.. | ..||..|.  ..|.|.||. ||.|||... ... |...||. |.|.|... .  ..|...
dyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld..ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeavee
0044763 (Phosphotyrosine protein) phosphatases II 108-263 2e-24 81.7 In-house 9-167 (178) alignment 
Range on Protein: 108-263
Range on HMM: 9-167/178.0
LNHVINKEVIPPENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLIPEEY---PQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLN
|... . | ... |.|.... .|..|.| .... .|.| |....|. | .| .   ....  ... .||. ..........| .    . .....| .|.
lsnleglersdyinaseilpglylgslppaddlellke.lgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeald

PANQPILIHCNRGKHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYD
. . |.|.||. |..|.|.|. . . | ...||  .....|.  .   .  .........
ekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRpivpnpgqlrqLyefe
0042113 (Phosphotyrosine protein) phosphatases II 115-263 1.2e-23 79.3 In-house 35-237 (245) alignment 
Range on Protein: 115-263
Range on HMM: 35-237/245.0
EVIPPENFSHV-----VGEIYRSSFPRQENFS----FLHErLKLKSILVLIPEEYPQEN----------------------------------------L
.. .. |.|.|      . ......| .|..     .|.| |....|. | .||. . .                                         
ldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwe.lgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlg

NFLKLTGIKLYQVGMSGNKEPF-VNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDEYRRFAfPKARALDQQF
.. ....| ...... ....|  ...   .|  ..... ...| |.|.||. |..|||..|.. .      |....||  ...|.|..  |.|.  ..|.
ddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR.pgavqtpsqy

IEMYD
. .|.
rflye
0036282 (Phosphotyrosine protein) phosphatases II 118-263 2.2e-22 75.0 In-house 8-164 (174) alignment 
Range on Protein: 118-263
Range on HMM: 8-164/174.0
PPENFSHVVGEIYRSSFPRQenFSFLHERLKLKSILVLIPEEYPQ---------ENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQ
.| ..|.. ........| .  |  .  .|...... |..|....         |. ..|. .||....... .. .| ..|  ...  . |..... . 
spldlsyitprliagqgpla..fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpgg

PILIHCNRGKHRTGCLIGCIRKLQNW--SLTMIFDEYR--RFAFPKARALDQQFIEMYD
|.|.||. |..|||.|... . |...  ||  ..| .|  |. .|..   ..|..  |.
pvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyy
0041856 (Phosphotyrosine protein) phosphatases II 121-263 2.3e-20 68.4 In-house 18-166 (182) alignment 
Range on Protein: 121-263
Range on HMM: 18-166/182.0
NFSHVVGEIYRSSFPR--------------QENFSFLHERlKLKSILVLIPEEYPQenlNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEivlnpA
... .   .|..|.|                ... .|.|. . ..|. | .| |.    ..|. .||....... ..  | ...  ... ..||      
dldyInanlylgslpatrfiatqgpllstvadflrmlkel.gittivnlteelywp...ellerlgiqylylpwpDhgvpdldelldfieevle.....e

NQPILIHCNRGKHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYD
. |.|.||. |..|||.|... . | ...||. .....|.  .     ..| |.... 
ggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqla
0049772 (Phosphotyrosine protein) phosphatases II 105-256 2.1e-19 65.8 In-house 119-265 (314) alignment 
Range on Protein: 105-256
Range on HMM: 119-265/314.0
MNTLNHVI---------------------NKEVIPPEnfshvvgeiyrsSFPRQENFSFLHerlklksilvliPEEYPQenlNFLKLTGIKLYQVGMSGN
.|. ..|.                     . .. ..             ..|  ... .|.            .| |..   .... .|||.... ....
lnvrdivmsrdevladelsrLdaAlgKtpllildgng............neptaadlellk............eelydp...elferlgikylripvpDg

KEPfvniPSHLLTKALEIVLN-PANQPILIHCNRGKHRTG--CLIGCIRKLQNWSLTMIFDEYRRFAF--PKARALDQ
 .|    ..  . ..||.... ... |.|.||. ||.|||  ...... ||...||  .....|.  .  |. ... |
sap....lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRpinpnpgfieq
0040438 (Phosphotyrosine protein) phosphatases II 146-264 5.6e-19 64.0 In-house 108-302 (317) alignment 
Range on Protein: 146-264
Range on HMM: 108-302/317.0
RLKLKSILVLIPEEYPQ---------------------ENLNFLKLTGIKLYQVGMSGNKE--------------PFVNIP--SHLLTKALEIVLNP---
......|. | ..|...                     ..|.. .| ||.|... ......              |  ..|    || . ||.| .    
eqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealed

ANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDEYRRFAfPKARALDQQ-------------------------------FIEMYDD
 . |.|.||. |..|||..|.. .      | ...... ...|.|..  |.|    .|                               .|... |
pggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqR.pgavqtpeqyrflydalleylkrkltlepaselklkllklliplald
0048179 (Phosphotyrosine protein) phosphatases II 120-249 1e-18 62.9 In-house 2-126 (144) alignment 
Range on Protein: 120-249
Range on HMM: 2-126/144.0
ENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLIPEEYPQENLNFlkltGIKLYQVGMSGNKEPfvNIPSHlLTKALEIV--LNPANQPILIHCNRG
 |.| ... .|..|.|  ... .|.. |... .. |..| .|..  ..    ||....... ..  |  ..... | ..||..  . . . |.|.||. |
snpseilpglylgslptaldlellkk.lgittvinlteeyepeflere....giqylhlpwpDhgvp..dllel.lleflefieealeeggpvlVHCsaG

KHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAFP
..|||.|. . . |....||  .....|.  . 
vgRtgtlvaaylmkklglsleealalvrsrrpg
0048076 (Phosphotyrosine protein) phosphatases II 119-248 3.4e-18 61.2 In-house 1-123 (145) alignment 
Range on Protein: 119-248
Range on HMM: 1-123/145.0
PENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLipeeypQENLNFLKLTGIKLYQVGMSGNKEPfvNIPSHlLTKALEIV--LNPANQPILIHCNR
| ..| ... .|..|.|  ... .|.. |... .| |        .|..|. .||....... .. .|  ..... | ..||..  . ... |.|.||. 
pywpseilpglylgslptaldlellkd.lgittvlnl......tselellerlgiqylylpwpDhgvp..dllel.lleflefieealkeggpvlVHCsa

GKHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAF
|..|||.|... . .|...||  .....|.  .
GvgRtgtlvaaylmlllgvsleealelvrsqrp
0039614 (Phosphotyrosine protein) phosphatases II 117-263 2.8e-17 58.6 In-house 65-283 (297) alignment 
Range on Protein: 117-263
Range on HMM: 65-283/297.0
IPPENFSHV--------------------------VGEIYRSSFPRQEN----FSFLHERlKLKSILVLIPEEYPQ-------------------ENLNF
|.| ..| |                            .......| .|.    . ...|  . ..|. | .... .                   ..|..
ilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweq.gvtvivmLtklvelgrkcaqywpeeggtygdftvtllkv

LKLTGIKLYQVGMSGNKEP-------FVNIPS-------HLLTKALEIVLN-----PANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDE
 .| |.....  .. |.|.       ....|         || ..||.| .     | . |.|.||. |..|||..|.. .      | .....  ...|
ehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavke

YRRFAfPKARALDQQFIEMYD
.|.   |.|.  ..|..  ||
lreqR.pgavqtpsqyrflyd
0043336 (Phosphotyrosine protein) phosphatases II 117-263 2.8e-17 58.5 In-house 54-271 (278) alignment 
Range on Protein: 117-263
Range on HMM: 54-271/278.0
IPPENFSHV------------------------VGEIYRSSFPRQEN----FSFLHERlKLKSILVLIPEEYPQ--------------------ENLNFL
|.| ..| |                          .......| .|.    . ...|  . ..|..| .... .                    ..|.. 
ilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwel.gvttivmLtelvelgrvkcaqYwpggsltygdftvtllkee

KLTGIKLYQVGMSGNKEPFVNI----------------PSHLLTKALEIVLN---PANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDEY
.| ......  .. ...... .                .  || . |..|..   . | |.|.||. |..|||..|.. .      | ....|  ...|.
hlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkel

RRFAfPKARALDQQFIEMYD
|..  |.|   ..|..  |.
reqR.pgavqtpsqyrflye
0037934 (Phosphotyrosine protein) phosphatases II 118-249 9.1e-15 50.3 In-house 35-222 (243) alignment 
Range on Protein: 118-249
Range on HMM: 35-222/243.0
PPENFSHVVGEIYRSSFPRQEN-------FSFLHERLKLKSILVLIPEE---------------------------------------YPQENLNFLKLT
 . |.. |.. ......| .|.       |  .  .|. ..|. | ...                                       .   .|. |...
inanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrl

GIKLYQVGMSGNKEPF-VNIPSHLLTKALEIVLN-------PANQPILIHCNRGKHRTGCLIGCIRKLQ--NWSLTMIFDEYRRFAFP
.|....... ... |  ...   .| .. |.. .       . . |.|.||  |..|||.|| .   |.  ...|  .....|.  . 
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpg
0045098 (Phosphotyrosine protein) phosphatases II 129-263 4.3e-13 44.7 In-house 29-266 (278) alignment 
Range on Protein: 129-263
Range on HMM: 29-266/278.0
IYRSSFP-----------------------------------------RQENFSFLHERlKLKSILVLIPEEYPQ-------------------------
.|.....                                          . .. .|.|  . ..|. | .... .                         
lylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwel.gitvivmltelvelgrekcaqywpeggsltygdftvtlls

--------------ENL----NFLKLTGIKLYQV-GMSGNKEPFVNIPSHLLTKALEIVL---------------NPANQPILIHCNRGKHRTGCLIGCI
              .||    . |.  |.. ..  ..  .  |  .| ...|    .|                 .. . |.|.||. |..|||.|... 
eevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaay

RKLQ----NWSLTMIFDEYRRFAfPK-ARALDQQFIEMYD
  |.    ...|  ...|.|.   |  |    .|.. .|.
lmlelleggvdlleavkelrsqR.pglavqnleqyrflye
0040439 (Phosphotyrosine protein) phosphatases II 117-247 1.3e-12 43.3 In-house 20-225 (249) alignment 
Range on Protein: 117-247
Range on HMM: 20-225/249.0
IPPENFSHVVGEIYRSSFPR---------------------------QENFSFLHERLKLKSILVLIPEEYPQ---------------------------
|.| ..| |. .|... |.                             |.|  .  .|. ..|. | ......                           
ilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsve

---------------ENLNFLKLTGIKLYQVGmSGNKEPFVNIPSHLLTKALEIVLNP-ANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIF
               .. . .. ..|  .      .  |....   .. ...... .   . |.|.||. |..|||..|..        | ....|  ..
vkddytvrtleltnlydgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeav

DEYRRFA
...|.  
kllrsqR
0045450 (Phosphotyrosine protein) phosphatases II 147-246 2.8e-10 35.9 In-house 130-282 (307) alignment 
Range on Protein: 147-246
Range on HMM: 130-282/307.0
LKLKSILVLIPEEYPQE----------------------NLNFLKLTGIKLYQVGMS---GNKE------------PFVNIPS--HLLTKALEIVLN---
.. . |. | ....                         .|.. .| |...... ..   |..|            |  ..|.    | . .|.|..   
qgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkale

--PANQPILIHCNRGKHRTGCLIGCIRKLQN---------WSLTMIFDEYRRF
  | . |.|.||. |. |||..|..   |..         ..|  .....|. 
elpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreq
0043147 (Phosphotyrosine protein) phosphatases II 144-246 5.3e-10 34.8 In-house 40-139 (172) alignment 
Range on Protein: 144-246
Range on HMM: 40-139/172.0
HERLKLKSILVLIPEeypQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEY
  .|. . |. | ..   . .  .|. .||... ...  .  |  ..  ..|    |....  . |.|.||  |. |||.|. .   |...||  .....
lkelgithivnltel...lydpellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylmllglsleeavalv

RRF
|. 
rek
0036941 (Phosphotyrosine protein) phosphatases II 148-245 1.1e-09 33.5 In-house 102-254 (297) alignment 
Range on Protein: 148-245
Range on HMM: 102-254/297.0
KLKSILVLIPEE----------YPQENLNFLKLTGIKLYQVGMSG-----------------------------NKEPFVNIP--SHLLTKALEIVLN--
. ..|..| ...          .| |. ..|.  ....  ....                               . |  ..|     | . .| |..  
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvl

---PANQPILIHCNRGKHRTGCLIGCIR---------KLQNWSLTMIFDEYRR
   | . |.|.||. |..|.|..|..           | .....  .. ..|.
kllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklRe
0049260 (Phosphotyrosine protein) phosphatases II 164-245 8.1e-09 30.8 In-house 46-127 (152) alignment 
Range on Protein: 164-245
Range on HMM: 46-127/152.0
NLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRR
.  .    .|. ... .  .  |   .    | ...|. .   . |.|.||  |. |||.|. .   |...||  ... .|.
lgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylmllgvsleeavalvre
0046846 (Phosphotyrosine protein) phosphatases II 115-245 8.9e-09 30.9 In-house 5-149 (176) alignment 
Range on Protein: 115-245
Range on HMM: 5-149/176.0
EVIPPENFSHVVGEIYRSSFP---------RQENFSFLHERLKLKSILVLIPEE-YPQ----E---NlnfLKLTGIKLYQVGMSGNKEPFVNIPSHLLTK
. ....... ... .. .|.|           ..|  .  .|. . .. |  |  . .            |.  ||. .....  .  |  ..  .||  
llgldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgiqylhlpwpDhgvpdlelllellef

ALEIVLNpaNQPILIHCNRGKHRTGCLIGCIRKLQ--NWSLTMIFDEYRR
  | . .  ..|.|.||  |. |||.|. .       ..|.  .....|.
irealke..ggpvlVHCsaGigRtgtlvaayllelekglsveealalvre
Y_phosphatase3 Tyrosine phosphatase family 185-244 1.7e-08 29.6 Pfam-A 103-161 (164) alignment 
Range on Protein: 185-244
Range on HMM: 103-161/164.0
EPFVNIPSHLLTKALEIVLNPAnQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYR
. ... . . ..|.||...... .|.|.||  || ||| ..  . .| . . . |...| 
reiledekkayrkvlealaeee.gpvlfHCtaGKDRTGvvaalllsllgvdeetiaaDYl
0038934 (Phosphotyrosine protein) phosphatases II 140-227 4.9e-07 25.1 In-house 47-135 (194) alignment 
Range on Protein: 140-227
Range on HMM: 47-135/194.0
FSFLHERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSG-NKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGC
...|... .    .. . ....  . . ..  ||. ..  . . .  |  .|  . |  . |.. . ... ...||  |. |||.|...
vrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa
0046845 (Phosphotyrosine protein) phosphatases II 198-235 2.6e-06 22.5 In-house 194-232 (284) alignment 
Range on Protein: 198-235
Range on HMM: 194-232/284.0
ALEIVLN-PANQPILIHCNRGKHRTGCLIGCIRKLQNWS
. |.  | | . ||..||  |. |||..| .   |. . 
vrellenlpgggpivVHCsaGvgRtGtfialdllleqle
0047943 (Phosphotyrosine protein) phosphatases II 199-236 3.3e-06 22.2 In-house 192-234 (273) alignment 
Range on Protein: 199-236
Range on HMM: 192-234/273.0
LEIVLN-----PANQPILIHCNRGKHRTGCLIGCIRKLQNWSL
.|.| .     | | |...||. |. |||..| .   |. .  
ielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlek
DUF3822 Protein of unknown function (DUF3822) 48-114 5e-06 12.2 Pfam-A 61-127 (253) alignment 
Range on Protein: 48-114
Range on HMM: 61-127/253.0
RDIHNIIQEDKLLSVEFNEVLKRFHGEEKSDIPRKEFDEDEDDGYDSNEHHQKTIEVMNTLNHVINK
... .|..|..||| .|.||   .. .. . .|.. |.|.... | .  .. |. |  ..|.....|
aelkeifeehellsqpfkeVkvlvanslftlVPeelFeeeqledylkfavnikeeeedfilydelek
0051299 (Phosphotyrosine protein) phosphatases II 199-238 5.3e-06 21.6 In-house 216-250 (288) alignment 
Range on Protein: 199-238
Range on HMM: 216-250/288.0
LeivlnPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTM
      . . |...||. |. |||..| .   |. .  . 
a.....sgggpvvVHCsaGvgRtgtfialdllleqlekeg
0050432 (Phosphotyrosine protein) phosphatases II 202-240 8.4e-06 20.8 In-house 230-265 (308) alignment 
Range on Protein: 202-240
Range on HMM: 230-265/308.0
VlnpANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIF
     . ||..||. |  |||..| .   |. .  .  .
l...pggpivVHCsaGvGRtGtfialdllleqlekeggv
RasGAP GTPase-activator protein for Ras-like GTPase 50-131 9.9e-06 12.7 Pfam-A 51-133 (197) alignment 
Range on Protein: 50-131
Range on HMM: 51-133/197.0
IHNIIQEDKLLSVEFNEVLKRFHGEEKSDIPRKEFDEDEDDGYDSNEHHQKTIEVMNTLNHVINKEV--IpPENFSHVVGEIYR
...|..||| | .  ... . .. ...... ..|. |||    . .....| .|..| . . | |..  . |. . ... .|. 
lqkilkedknlelDprkiyeklrkkkeerksseeasedekedqeleknidklrelvneileaIfksledl.Pqgiriickqire