Gene SIW14 in Saccharomyces cerevisiae

Synonym: OCA3, YNL032W, SIW14

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP055_AA protein Get Run
ScerP055_AA_104-264 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Y_phosphatase2 Tyrosine phosphatase family 116-276 1.3e-70 228.4 Pfam-A 1-161 (165) alignment
Range on Protein: 116-276
Range on HMM: 1-161/165.0
VIPPENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCN
..||.|||.|. |.||||.||..|||||.. ||||.|..|.|||..|..|.||. . ||||.. ...|||..|.|.|.||.|||...|| .|.|.|.||.
lvpplnFsaveselyrssyprasnfsflks.LkLktiislspeeesqdelqfleeekiklyhiaiesnkeelveiksdllkkalklllnkenypvllhck

RGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYDDDEIKRIAS-KNNW
|||||||..|||.||||.|||..|..|||||. .|.|..|..|||..|.. ... .. |...
rGkhrtglvigclRklqkWslasilnEyrrFsgskkrivdeefienfdselevekknkklkv

subfamily_OCA_pd Subfamily OCA 104-263 1e-36 116.8 In-house 132-282 (282) alignment
Range on Protein: 104-263
Range on HMM: 132-282/282.0
VMNTLNHVINKEVIPPENFSHVVG--------EIYRSSFPRQENFSFLHERLKLKSILVLIPEEYPQENL-NFLKLTGIKLYQVGMsgnkepfvnipshl
...|.... .....||.|||.|          ...|.. |..||..||..||.||..|.| .||...|.. .||. . |||... .              
ifgthffprlyslvpprnfslveeykdkpvisgllrlllpeeenlpfLidrlglktaliLdaeeveretiadflasseiklvslrn..............

ltKALEIVLNPANQPILIHCnrgKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAF-PKARALDQQFIEMYD
  ..|...|.  | .....|   ...|.......||......|.|..||..|.   ...  ....||..|
..evlkdlldndnyavelsc...qaktdtvlkvLrkdkkygstsiyleyigFtledqeslksillielfd

0051082 (Phosphotyrosine protein) phosphatases II 116-263 2.7e-35 116.6 In-house 2-148 (151) alignment
Range on Protein: 116-263
Range on HMM: 2-148/151.0
VIPPENFSHVVGEIYRSSFPRQENFSFLhERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCN
. .. ||| | | .|||..| .... .| ..|..|.|. | .||... . ..|. .||..... . ....| . .  . . ..||..|.. |.|.|.||.
lsdyinfsyvtgglyrsggpladflell.kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCs

RGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYD
 ||.|||.|......|...||  ...|||.. . . .  .|.......
aGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnqqflfqlfa

0051429 (Phosphotyrosine protein) phosphatases II 108-256 2e-27 91.9 In-house 3-199 (272) alignment
Range on Protein: 108-256
Range on HMM: 3-199/272.0
LNHVINKEVIPPENFSHVVGEIYRSSFP---RQENFSFLhERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVN---------------
|...||   ..  .   . | .|||..|    ...| .| ..|..|.|. | .||. . .  .. . ||..... . .. .|...               
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll

---------------------------------IPSHLLTKALEIVLNpaNQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQ
                                 .|.. | ..||..|.  ..|.|.||. ||.|||... ... |...||. |.|.|... .  ..|...
dyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld..ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeavee





0044763 (Phosphotyrosine protein) phosphatases II 108-263 2e-24 81.7 In-house 9-167 (178) alignment
Range on Protein: 108-263
Range on HMM: 9-167/178.0
LNHVINKEVIPPENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLIPEEY---PQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLN
|... . | ... |.|.... .|..|.| .... .|.| |....|. | .| .   ....  ... .||. ..........| .    . .....| .|.
lsnleglersdyinaseilpglylgslppaddlellke.lgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeald

PANQPILIHCNRGKHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYD
. . |.|.||. |..|.|.|. . . | ...||  .....|.  .   .  .........
ekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRpivpnpgqlrqLyefe

0042113 (Phosphotyrosine protein) phosphatases II 115-263 1.2e-23 79.3 In-house 35-237 (245) alignment
Range on Protein: 115-263
Range on HMM: 35-237/245.0
EVIPPENFSHV-----VGEIYRSSFPRQENFS----FLHErLKLKSILVLIPEEYPQEN----------------------------------------L
.. .. |.|.|      . ......| .|..     .|.| |....|. | .||. . .                                         
ldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwe.lgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlg

NFLKLTGIKLYQVGMSGNKEPF-VNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDEYRRFAfPKARALDQQF
.. ....| ...... ....|  ...   .|  ..... ...| |.|.||. |..|||..|.. .      |....||  ...|.|..  |.|.  ..|.
ddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR.pgavqtpsqy

IEMYD
. .|.
rflye

0036282 (Phosphotyrosine protein) phosphatases II 118-263 2.2e-22 75.0 In-house 8-164 (174) alignment
Range on Protein: 118-263
Range on HMM: 8-164/174.0
PPENFSHVVGEIYRSSFPRQenFSFLHERLKLKSILVLIPEEYPQ---------ENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQ
.| ..|.. ........| .  |  .  .|...... |..|....         |. ..|. .||....... .. .| ..|  ...  . |..... . 
spldlsyitprliagqgpla..fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpgg

PILIHCNRGKHRTGCLIGCIRKLQNW--SLTMIFDEYR--RFAFPKARALDQQFIEMYD
|.|.||. |..|||.|... . |...  ||  ..| .|  |. .|..   ..|..  |.
pvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyy

0041856 (Phosphotyrosine protein) phosphatases II 121-263 2.3e-20 68.4 In-house 18-166 (182) alignment
Range on Protein: 121-263
Range on HMM: 18-166/182.0
NFSHVVGEIYRSSFPR--------------QENFSFLHERlKLKSILVLIPEEYPQenlNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEivlnpA
... .   .|..|.|                ... .|.|. . ..|. | .| |.    ..|. .||....... ..  | ...  ... ..||      
dldyInanlylgslpatrfiatqgpllstvadflrmlkel.gittivnlteelywp...ellerlgiqylylpwpDhgvpdldelldfieevle.....e

NQPILIHCNRGKHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYD
. |.|.||. |..|||.|... . | ...||. .....|.  .     ..| |.... 
ggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqla

0049772 (Phosphotyrosine protein) phosphatases II 105-256 2.1e-19 65.8 In-house 119-265 (314) alignment
Range on Protein: 105-256
Range on HMM: 119-265/314.0
MNTLNHVI---------------------NKEVIPPEnfshvvgeiyrsSFPRQENFSFLHerlklksilvliPEEYPQenlNFLKLTGIKLYQVGMSGN
.|. ..|.                     . .. ..             ..|  ... .|.            .| |..   .... .|||.... ....
lnvrdivmsrdevladelsrLdaAlgKtpllildgng............neptaadlellk............eelydp...elferlgikylripvpDg

KEPfvniPSHLLTKALEIVLN-PANQPILIHCNRGKHRTG--CLIGCIRKLQNWSLTMIFDEYRRFAF--PKARALDQ
 .|    ..  . ..||.... ... |.|.||. ||.|||  ...... ||...||  .....|.  .  |. ... |
sap....lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRpinpnpgfieq

0040438 (Phosphotyrosine protein) phosphatases II 146-264 5.6e-19 64.0 In-house 108-302 (317) alignment
Range on Protein: 146-264
Range on HMM: 108-302/317.0
RLKLKSILVLIPEEYPQ---------------------ENLNFLKLTGIKLYQVGMSGNKE--------------PFVNIP--SHLLTKALEIVLNP---
......|. | ..|...                     ..|.. .| ||.|... ......              |  ..|    || . ||.| .    
eqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealed

ANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDEYRRFAfPKARALDQQ-------------------------------FIEMYDD
 . |.|.||. |..|||..|.. .      | ...... ...|.|..  |.|    .|                               .|... |
pggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqR.pgavqtpeqyrflydalleylkrkltlepaselklkllklliplald

0048179 (Phosphotyrosine protein) phosphatases II 120-249 1e-18 62.9 In-house 2-126 (144) alignment
Range on Protein: 120-249
Range on HMM: 2-126/144.0
ENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLIPEEYPQENLNFlkltGIKLYQVGMSGNKEPfvNIPSHlLTKALEIV--LNPANQPILIHCNRG
 |.| ... .|..|.|  ... .|.. |... .. |..| .|..  ..    ||....... ..  |  ..... | ..||..  . . . |.|.||. |
snpseilpglylgslptaldlellkk.lgittvinlteeyepeflere....giqylhlpwpDhgvp..dllel.lleflefieealeeggpvlVHCsaG

KHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAFP
..|||.|. . . |....||  .....|.  . 
vgRtgtlvaaylmkklglsleealalvrsrrpg

0048076 (Phosphotyrosine protein) phosphatases II 119-248 3.4e-18 61.2 In-house 1-123 (145) alignment
Range on Protein: 119-248
Range on HMM: 1-123/145.0
PENFSHVVGEIYRSSFPRQENFSFLHErLKLKSILVLipeeypQENLNFLKLTGIKLYQVGMSGNKEPfvNIPSHlLTKALEIV--LNPANQPILIHCNR
| ..| ... .|..|.|  ... .|.. |... .| |        .|..|. .||....... .. .|  ..... | ..||..  . ... |.|.||. 
pywpseilpglylgslptaldlellkd.lgittvlnl......tselellerlgiqylylpwpDhgvp..dllel.lleflefieealkeggpvlVHCsa

GKHRTGCLIGC-IRKLQNWSLTMIFDEYRRFAF
|..|||.|... . .|...||  .....|.  .
GvgRtgtlvaaylmlllgvsleealelvrsqrp

0039614 (Phosphotyrosine protein) phosphatases II 117-263 2.8e-17 58.6 In-house 65-283 (297) alignment
Range on Protein: 117-263
Range on HMM: 65-283/297.0
IPPENFSHV--------------------------VGEIYRSSFPRQEN----FSFLHERlKLKSILVLIPEEYPQ-------------------ENLNF
|.| ..| |                            .......| .|.    . ...|  . ..|. | .... .                   ..|..
ilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweq.gvtvivmLtklvelgrkcaqywpeeggtygdftvtllkv

LKLTGIKLYQVGMSGNKEP-------FVNIPS-------HLLTKALEIVLN-----PANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDE
 .| |.....  .. |.|.       ....|         || ..||.| .     | . |.|.||. |..|||..|.. .      | .....  ...|
ehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavke

YRRFAfPKARALDQQFIEMYD
.|.   |.|.  ..|..  ||
lreqR.pgavqtpsqyrflyd

0043336 (Phosphotyrosine protein) phosphatases II 117-263 2.8e-17 58.5 In-house 54-271 (278) alignment
Range on Protein: 117-263
Range on HMM: 54-271/278.0
IPPENFSHV------------------------VGEIYRSSFPRQEN----FSFLHERlKLKSILVLIPEEYPQ--------------------ENLNFL
|.| ..| |                          .......| .|.    . ...|  . ..|..| .... .                    ..|.. 
ilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwel.gvttivmLtelvelgrvkcaqYwpggsltygdftvtllkee

KLTGIKLYQVGMSGNKEPFVNI----------------PSHLLTKALEIVLN---PANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIFDEY
.| ......  .. ...... .                .  || . |..|..   . | |.|.||. |..|||..|.. .      | ....|  ...|.
hlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkel

RRFAfPKARALDQQFIEMYD
|..  |.|   ..|..  |.
reqR.pgavqtpsqyrflye

0037934 (Phosphotyrosine protein) phosphatases II 118-249 9.1e-15 50.3 In-house 35-222 (243) alignment
Range on Protein: 118-249
Range on HMM: 35-222/243.0
PPENFSHVVGEIYRSSFPRQEN-------FSFLHERLKLKSILVLIPEE---------------------------------------YPQENLNFLKLT
 . |.. |.. ......| .|.       |  .  .|. ..|. | ...                                       .   .|. |...
inanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrl

GIKLYQVGMSGNKEPF-VNIPSHLLTKALEIVLN-------PANQPILIHCNRGKHRTGCLIGCIRKLQ--NWSLTMIFDEYRRFAFP
.|....... ... |  ...   .| .. |.. .       . . |.|.||  |..|||.|| .   |.  ...|  .....|.  . 
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpg

0045098 (Phosphotyrosine protein) phosphatases II 129-263 4.3e-13 44.7 In-house 29-266 (278) alignment
Range on Protein: 129-263
Range on HMM: 29-266/278.0
IYRSSFP-----------------------------------------RQENFSFLHERlKLKSILVLIPEEYPQ-------------------------
.|.....                                          . .. .|.|  . ..|. | .... .                         
lylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwel.gitvivmltelvelgrekcaqywpeggsltygdftvtlls

--------------ENL----NFLKLTGIKLYQV-GMSGNKEPFVNIPSHLLTKALEIVL---------------NPANQPILIHCNRGKHRTGCLIGCI
              .||    . |.  |.. ..  ..  .  |  .| ...|    .|                 .. . |.|.||. |..|||.|... 
eevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaay

RKLQ----NWSLTMIFDEYRRFAfPK-ARALDQQFIEMYD
  |.    ...|  ...|.|.   |  |    .|.. .|.
lmlelleggvdlleavkelrsqR.pglavqnleqyrflye

0040439 (Phosphotyrosine protein) phosphatases II 117-247 1.3e-12 43.3 In-house 20-225 (249) alignment
Range on Protein: 117-247
Range on HMM: 20-225/249.0
IPPENFSHVVGEIYRSSFPR---------------------------QENFSFLHERLKLKSILVLIPEEYPQ---------------------------
|.| ..| |. .|... |.                             |.|  .  .|. ..|. | ......                           
ilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsve

---------------ENLNFLKLTGIKLYQVGmSGNKEPFVNIPSHLLTKALEIVLNP-ANQPILIHCNRGKHRTGCLIGCIR------KLQNWSLTMIF
               .. . .. ..|  .      .  |....   .. ...... .   . |.|.||. |..|||..|..        | ....|  ..
vkddytvrtleltnlydgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeav

DEYRRFA
...|.  
kllrsqR

0045450 (Phosphotyrosine protein) phosphatases II 147-246 2.8e-10 35.9 In-house 130-282 (307) alignment
Range on Protein: 147-246
Range on HMM: 130-282/307.0
LKLKSILVLIPEEYPQE----------------------NLNFLKLTGIKLYQVGMS---GNKE------------PFVNIPS--HLLTKALEIVLN---
.. . |. | ....                         .|.. .| |...... ..   |..|            |  ..|.    | . .|.|..   
qgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkale

--PANQPILIHCNRGKHRTGCLIGCIRKLQN---------WSLTMIFDEYRRF
  | . |.|.||. |. |||..|..   |..         ..|  .....|. 
elpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreq

0043147 (Phosphotyrosine protein) phosphatases II 144-246 5.3e-10 34.8 In-house 40-139 (172) alignment
Range on Protein: 144-246
Range on HMM: 40-139/172.0
HERLKLKSILVLIPEeypQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEY
  .|. . |. | ..   . .  .|. .||... ...  .  |  ..  ..|    |....  . |.|.||  |. |||.|. .   |...||  .....
lkelgithivnltel...lydpellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylmllglsleeavalv

RRF
|. 
rek

0036941 (Phosphotyrosine protein) phosphatases II 148-245 1.1e-09 33.5 In-house 102-254 (297) alignment
Range on Protein: 148-245
Range on HMM: 102-254/297.0
KLKSILVLIPEE----------YPQENLNFLKLTGIKLYQVGMSG-----------------------------NKEPFVNIP--SHLLTKALEIVLN--
. ..|..| ...          .| |. ..|.  ....  ....                               . |  ..|     | . .| |..  
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvl

---PANQPILIHCNRGKHRTGCLIGCIR---------KLQNWSLTMIFDEYRR
   | . |.|.||. |..|.|..|..           | .....  .. ..|.
kllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklRe

0049260 (Phosphotyrosine protein) phosphatases II 164-245 8.1e-09 30.8 In-house 46-127 (152) alignment
Range on Protein: 164-245
Range on HMM: 46-127/152.0
NLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRR
.  .    .|. ... .  .  |   .    | ...|. .   . |.|.||  |. |||.|. .   |...||  ... .|.
lgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylmllgvsleeavalvre

0046846 (Phosphotyrosine protein) phosphatases II 115-245 8.9e-09 30.9 In-house 5-149 (176) alignment
Range on Protein: 115-245
Range on HMM: 5-149/176.0
EVIPPENFSHVVGEIYRSSFP---------RQENFSFLHERLKLKSILVLIPEE-YPQ----E---NlnfLKLTGIKLYQVGMSGNKEPFVNIPSHLLTK
. ....... ... .. .|.|           ..|  .  .|. . .. |  |  . .            |.  ||. .....  .  |  ..  .||  
llgldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgiqylhlpwpDhgvpdlelllellef

ALEIVLNpaNQPILIHCNRGKHRTGCLIGCIRKLQ--NWSLTMIFDEYRR
  | . .  ..|.|.||  |. |||.|. .       ..|.  .....|.
irealke..ggpvlVHCsaGigRtgtlvaayllelekglsveealalvre

Y_phosphatase3 Tyrosine phosphatase family 185-244 1.7e-08 29.6 Pfam-A 103-161 (164) alignment
Range on Protein: 185-244
Range on HMM: 103-161/164.0
EPFVNIPSHLLTKALEIVLNPAnQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYR
. ... . . ..|.||...... .|.|.||  || ||| ..  . .| . . . |...| 
reiledekkayrkvlealaeee.gpvlfHCtaGKDRTGvvaalllsllgvdeetiaaDYl

0038934 (Phosphotyrosine protein) phosphatases II 140-227 4.9e-07 25.1 In-house 47-135 (194) alignment
Range on Protein: 140-227
Range on HMM: 47-135/194.0
FSFLHERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSG-NKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGC
...|... .    .. . ....  . . ..  ||. ..  . . .  |  .|  . |  . |.. . ... ...||  |. |||.|...
vrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa

0046845 (Phosphotyrosine protein) phosphatases II 198-235 2.6e-06 22.5 In-house 194-232 (284) alignment
Range on Protein: 198-235
Range on HMM: 194-232/284.0
ALEIVLN-PANQPILIHCNRGKHRTGCLIGCIRKLQNWS
. |.  | | . ||..||  |. |||..| .   |. . 
vrellenlpgggpivVHCsaGvgRtGtfialdllleqle

0047943 (Phosphotyrosine protein) phosphatases II 199-236 3.3e-06 22.2 In-house 192-234 (273) alignment
Range on Protein: 199-236
Range on HMM: 192-234/273.0
LEIVLN-----PANQPILIHCNRGKHRTGCLIGCIRKLQNWSL
.|.| .     | | |...||. |. |||..| .   |. .  
ielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlek

DUF3822 Protein of unknown function (DUF3822) 48-114 5e-06 12.2 Pfam-A 61-127 (253) alignment
Range on Protein: 48-114
Range on HMM: 61-127/253.0
RDIHNIIQEDKLLSVEFNEVLKRFHGEEKSDIPRKEFDEDEDDGYDSNEHHQKTIEVMNTLNHVINK
... .|..|..||| .|.||   .. .. . .|.. |.|.... | .  .. |. |  ..|.....|
aelkeifeehellsqpfkeVkvlvanslftlVPeelFeeeqledylkfavnikeeeedfilydelek

0051299 (Phosphotyrosine protein) phosphatases II 199-238 5.3e-06 21.6 In-house 216-250 (288) alignment
Range on Protein: 199-238
Range on HMM: 216-250/288.0
LeivlnPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTM
      . . |...||. |. |||..| .   |. .  . 
a.....sgggpvvVHCsaGvgRtgtfialdllleqlekeg

0050432 (Phosphotyrosine protein) phosphatases II 202-240 8.4e-06 20.8 In-house 230-265 (308) alignment
Range on Protein: 202-240
Range on HMM: 230-265/308.0
VlnpANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIF
     . ||..||. |  |||..| .   |. .  .  .
l...pggpivVHCsaGvGRtGtfialdllleqlekeggv

RasGAP GTPase-activator protein for Ras-like GTPase 50-131 9.9e-06 12.7 Pfam-A 51-133 (197) alignment
Range on Protein: 50-131
Range on HMM: 51-133/197.0
IHNIIQEDKLLSVEFNEVLKRFHGEEKSDIPRKEFDEDEDDGYDSNEHHQKTIEVMNTLNHVINKEV--IpPENFSHVVGEIYR
...|..||| | .  ... . .. ...... ..|. |||    . .....| .|..| . . | |..  . |. . ... .|. 
lqkilkedknlelDprkiyeklrkkkeerksseeasedekedqeleknidklrelvneileaIfksledl.Pqgiriickqire