Gene TEP1 in Saccharomyces cerevisiae

Synonym: YNL128W, TEP1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTEN
Subfamily PTEN
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP061_AA protein Get Run
ScerP061_AA_20-254 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTEN_pd Subfamily PTEN 23-256 3.9e-67 220.8 In-house 2-183 (184) alignment
Range on Protein: 23-256
Range on HMM: 2-183/184.0
MKKILSLPMKKTKNDiGLRLDISYILVNLIVCSYPVnTYPKLLYRNSLDDLILFLTVYHgKGNFRIFNFRGEKedsdykdndligiaaKFESKDFeiqel
..||.| ..|..|.| ||.||.|||. |.|...||. .... ||||||.|.. ||. .| |....|.|.|.|.               |..||.|     
lrkivskkkkrfked.gldLDlsyiteniiamgyPa.eklealyRnsledvvkflekkh.kdhykiynlrser...............kydskkf.....

rstlinDGKIPISPIDletrtlveeetnnvicerigwlDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLG-EARL
      ||.....|.|                      ||.|||.|||||||. ||..|...|..|.|.||..||||.|...||||.|.|...   ||. 
......dgrvavypfd......................DhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeeale

IFMQARFKYGmtNGVTIPSQLRYLRYHEFFITHEK
.|..||.|..  .|||||||.||..|.|.....||
lfaeaRtknk..kgvtiPsqrRYveYyeklleeek

0036282 (Phosphotyrosine protein) phosphatases II 42-251 1e-27 92.3 In-house 10-168 (174) alignment
Range on Protein: 42-251
Range on HMM: 10-168/174.0
LDISYILVNLIVCSYPVNtYPKLLYRNSLDDLILFLTVYHgKGNFRIFNFRGEkedsdykdndligiaakfeskdfeiqelrstlindgkipispidlet
||.|||. .||....| . . ..|..... ... .|. .. .|.....|.  |                                               
ldlsyitprliagqgpla.fwemlkelgittvvmlleeke.lglykcinywpe...............................................

rTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQC-PLGEARLIFMQARFKygMTNGVTIPS
 .   .| ...   ...| || .|... |.|.|. .|..|| ..... . ||..|.||.|.. .||||..... .| .|  .. ..|..    ..|..||
.lredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlq..rpgmvqtps

QLRYLRYHEFF
|.|.|.|.| .
Qyrflyyfekl

0041856 (Phosphotyrosine protein) phosphatases II 41-254 5.3e-25 83.5 In-house 16-172 (182) alignment
Range on Protein: 41-254
Range on HMM: 16-172/182.0
RLDISYILVNLIVCSYPVNTYPkLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKdndligiaakfeskdfeiqelrstlindgkipispidle
 .|..||. ||...|.| ...  . ... |...  ||. ... |   | | ..|  . ..                                        
srdldyInanlylgslpatrfi.atqgpllstvadflrmlkelgittivnlteelywpell.......................................

trtlveeETNNVICERIGWLDHFPPPFELLEEIVDGIENylsvsKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKygmtnGVTIPS
       | ...   ...| || .|... | .... ...     .... . ||..|.||.|.. .|||||.|...| ||   . ..|..     .|..|.
.......erlgiqylylpwpDhgvpdldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpg.....mvitpn

QLRYLRYHEFFITH
|...|.. .... .
qyfflqlallelll

0037934 (Phosphotyrosine protein) phosphatases II 28-251 2.5e-24 81.6 In-house 6-240 (243) alignment
Range on Protein: 28-251
Range on HMM: 6-240/243.0
SLPMKKTKN-----------------DIGLRLDISYILVNLIVCSYPVNTypkllyrNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGiaA
.||. ..||                 .  . .. .|.. .||....| .        .  |||  |.   .  |   | ... ..| . .|   .     
llpenlsknrysdilpydhsrvklegsdyinanliyvtprliatqgPlpe.......tveddlasfwrmlwelgitvivmltelvElgrekcaqywp..g

KFESKDFEIQELRSTLINDgkIPISPIDLETRTLVEEETNNVICERIGWLDHFPPP-FELLEEIVDGIENYLSV-------SKNRVAVLHCRMGKGRSGM
... .||... | ..  .|  . .  . ||   | ... ...   ...| || .|. .| | ...| . ....        ..... ..||..|.||.|.
evtygdftvtllseehldd..ytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGt

ITVAYLMKYL-QCPLGEARLIFMQARFKygmtNGVTIPSQLRYLRYHEFF
. .||||..| ...| ||   . . |.      .|..|||.|.|.... .
liaaylmllllgvdleeavkllreqRpg....kavqtpsqyrflyealle

0044763 (Phosphotyrosine protein) phosphatases II 39-252 1.2e-23 79.1 In-house 18-170 (178) alignment
Range on Protein: 39-252
Range on HMM: 18-170/178.0
GLRLDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGnFRIFNFR----Gekedsdykdndligiaakfeskdfeiqelrstlindgkipi
.  ...|.|| .|...|.|   ...||... .. .. . . ...   .  .       |                                         
sdyinaseilpglylgslppaddlellkelgithivnlteelelgf.lkcdpywpeeag.........................................

spidletrtlveeetnnVICERIGWLDHFPPP-FELLEEIVDGIENYLSVSKNRVAVlHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARfkygmT
                 .   .|.. || .|. .| ..|.|. ||..|. ....|.| ||..|.||||.. .|||||.|...| ||   . ..|      
.................iqylhipipDhgvpdllehflefvefieealdekggpvlV.HCsaGvgRsgtlvaaylmkklglsleeaielvrerR.....p

nGVTIPSQLRYLRYHEFFI
 .|. |.|||.|.. | ..
.ivpnpgqlrqLyefelrl

0043147 (Phosphotyrosine protein) phosphatases II 42-251 2.4e-22 74.9 In-house 13-159 (172) alignment
Range on Protein: 42-251
Range on HMM: 13-159/172.0
LDISYILVNLIVCSYPvntypkllYRNSLDDLILFLTVYHGKGnfrIFNFRGEkedsdykdndligiaakfeskdfeiqelrstlindgkipispidleT
||..||  ..|.. .|        .|| |.| . .|  .. .    |.|  ..                                              .
ldlyyipdrfiatqgp........lrntladfwrmlkelgith...ivnltel..............................................l

RTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKyLQCPLGEARLIFMQARfkygmTNGVTIPSQ
 .   .| ...   ...| || .|..|||.|... |...| .|.. . . ||..|.||.|.. .||||. |...| ||   . ..|      ..|..|||
ydpellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekR.....pgavqnpsq

LRYLRYHEFF
.|.|.|.| .
yrflyyfekl

0049772 (Phosphotyrosine protein) phosphatases II 148-251 7.8e-22 73.8 In-house 177-276 (314) alignment
Range on Protein: 148-251
Range on HMM: 177-276/314.0
ETNNVICERIGWLDHFPPPFELLEEIVDGIENYlsvSKNRVAVLHCRMGKGRSG-MITVAYLMKYLQCPLGEARLIFMQARFkyGMTNGVTIPSQLRYLR
| ...   || . |. .|..| ..|... ||..   .|... . ||..||||.| ....|||||.|...| ||   ....|.     | ..|.....|. 
erlgikylripvpDgsaplledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp..inpnpgfieqleqyef

YHEFF
..|. 
ileal

0046846 (Phosphotyrosine protein) phosphatases II 39-250 3.7e-21 71.1 In-house 7-170 (176) alignment
Range on Protein: 39-250
Range on HMM: 7-170/176.0
GLRLDISYILVNLIVCSYPVNTYPKLlyrnsLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESkdfeiqelrstlindgkipispid
||.||..||. |||..|.|. |.  |      ..|  ||  ..  |   ..|.  |.| . .|  ..  .  |..                         
gldldldyinanlilgsrpiatqgpl.....prtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi........................

letrtlveeetnnvICERIGWLDHFPPPFELLEEIVDGIENYLSvsKNRVAVLHCRMGKGRSGMITVAYLMKY-LQCPLGEARLIFMQARFKygmtNGVT
                 ...| || .|..|||.|... |...|.  .... . ||..|.||.|.. .|||...  . .. ||   . . |..    . |.
..............qylhlpwpDhgvpdlelllellefirealk..eggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRpl....gavq

IPSQLRYLRYHEF
 |.|.|.|.. | 
tpeQyrflyefel

PTEN_1 144-250 2.9e-20 67.9 In-house 87-190 (196) alignment
Range on Protein: 144-250
Range on HMM: 87-190/196.0
LVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSK-NRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYGMTngvtIPSQL
| |.. ..|.  .... || .|... | .|.. ....|.  . ..|.. ||. |.||||..  ||||.. .    ||  .. ..| . .      .||| 
leeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapn....spsqe

RYLRYHEF
|.|.| . 
rlleyfae

0048179 (Phosphotyrosine protein) phosphatases II 61-249 4.3e-19 64.1 In-house 8-141 (144) alignment
Range on Protein: 61-249
Range on HMM: 8-141/144.0
YPKlLYRNSLDDLILFLTVYHgKGNFRIFNFRGEKEDSDYKDNdligiaakfeskdfeiqelrstlindgkipispidletrtlveeetnNVICERIGWL
.|. ||..|| ... . .  .  |   ..|.. | |  .....                                               ..   ...| 
lpg.lylgslptaldlellkk.lgittvinlteeyepeflere...............................................giqylhlpwp

DHFPPPF-ELLEEIVDGIENYLSvsKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFkygmtNGVTIPSQLRYLRYHE
|| .|.. |||.|... ||..|.  .... . ||..|.||.|.. .|||||.|...| ||   . ..|.     ..|. |.|||.|.. |
Dhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrp.....gavpnpgqlrfLleye

0039614 (Phosphotyrosine protein) phosphatases II 21-250 7.2e-18 60.5 In-house 45-286 (297) alignment
Range on Protein: 21-250
Range on HMM: 45-286/297.0
NLMKKILSLPMKKTKN-----------------DIGLRLDISYI-----------LVNLIVCSYPVNTYP----KLLYRNSLDDLI--------------
.  ..|  ||  |.||                   |  || .||             . |....| .  .    ......    ..              
kpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaq

--------------LFLTVYHgKGNFRIFNFRGekedsdykdndligiaakfeskdfeiqelrsTLiNDgkipispidletrtlveEETNNVICERIGWL
               .|.|.| .... .....                                |  |.                 |.        .|| 
ywpeeggtygdftvtllkveh.ldgytvrtlev...............................tn.ng.................esrtvthfqytgwp

DHFPPP-FELLEEIVDGIENYLSVS-KNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARfkygmTNGVTIPSQLRYLRYHEF
|| .|| .||| |... ....|. . |... . || .|.||.|.. .||||     |. .  . ||   . ..|      ..|..|||.|.|.. ..
dhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqR.....pgavqtpsqyrflydall

0048076 (Phosphotyrosine protein) phosphatases II 147-250 7.9e-18 60.0 In-house 43-140 (145) alignment
Range on Protein: 147-250
Range on HMM: 43-140/145.0
EETNNVICERIGWLDHFPPPF-ELLEEIVDGIENYLSvsKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKygmtnGVTIPSQLRYL
.| ...   ...| || .|.. |||.|... ||..|.  .... . ||..|.||.|.. .||||..|...| ||   . ..|..     .|. |.|||.|
lerlgiqylylpwpDhgvpdllellleflefieealk..eggpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpg.....avpnpgqlrfl

RYHEF
.. | 
yefel

0038934 (Phosphotyrosine protein) phosphatases II 150-233 2.4e-17 58.7 In-house 78-157 (194) alignment
Range on Protein: 150-233
Range on HMM: 78-157/194.0
NNVICERIGWLDH-FPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARfkygmT
...   .. . |. ..|..|.| ...| .. .|. ... | . || .|.||.|.. .|||...|.... ||  .| ..|      
agieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekR.....p

0042113 (Phosphotyrosine protein) phosphatases II 146-250 5e-17 57.6 In-house 135-240 (245) alignment
Range on Protein: 146-250
Range on HMM: 135-240/245.0
EEETNNVICERIGWLDHFPPP-FELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARfkygmTNGVTIP
 |. ...   ...| || .|.  |||..... ....|. ..| . . ||..|.||.|.. .||||     |.|  .| ||   . . |      . |..|
desrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR.....pgavqtp

SQLRYLRYHEF
||.|.|.. ..
sqyrflyeall

0049260 (Phosphotyrosine protein) phosphatases II 153-249 6.3e-17 57.1 In-house 56-146 (152) alignment
Range on Protein: 153-249
Range on HMM: 56-146/152.0
ICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKyLQCPLGEARLIFMQARfkygmTNGVTIPSQLRYLRYHE
   .. | || .|... | ...  . . |  .|. . . ||. |.||.|.. .||||. |...| ||   . ..|      ..|. |.|||.| . |
qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekR.....pgavpnpgqlrflyefe

subfamily_Tensin_pd Subfamily Tensin 155-253 1.1e-16 53.9 In-house 73-172 (189) alignment
Range on Protein: 155-253
Range on HMM: 73-172/189.0
ERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYlMKYLQCPLGEARLI--FMQARFKYGMTNGVTIPSQLRYLRYHEFFI
  .|| |.  |..| |  |.  ....|.   ..|.|.||. |||| |..  || ||| .   ..   .  |   ||    ..|.| ||| ||..| . ..
ldfGWPdllaPsleklcsicksldsWlkadpqnvvvvhckGgkgrigvvvsay.mkyskisasadaaldrfamkrflddklsgetqPsqrryveyfsglL

T
.
s

0051082 (Phosphotyrosine protein) phosphatases II 42-249 8.4e-16 53.4 In-house 6-148 (151) alignment
Range on Protein: 42-249
Range on HMM: 6-148/151.0
LDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGNFRIFNFRGekedsdykdndligiaakfeskdfeiqelrstlindgkipispidlet
...||.  .|.....| . . .||... ..  . . . .. . . ....  |                                                
infsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelg................................................

rtlveeetnnVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKyLQCPLGEARLIFMQARFkygmtnGVTIPSQ
          .   .| .||. .|...|. ..|  . ..|   || . . ||..||||.|.. ..|||. |...| ||   ... |.      ||..|.|
..........ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrp......gvvqpnq

LRYLRYHE
 ... ...
qflfqlfa

0045450 (Phosphotyrosine protein) phosphatases II 64-251 3.4e-15 52.0 In-house 160-302 (307) alignment
Range on Protein: 64-251
Range on HMM: 160-302/307.0
LLYRNsldDLILFLTVYHgKGNFRIFNFRGEKEDS-DykdndligiaakfeskdfeiqelrstlindgkipispidletrtlveEETNNVICERIGWLDH
| |.|   . . .| ..| .... ..... .  |  .                                               |.    .   .|| ||
ltygn...ftvtllseeh.ldgytvrtlevtdldgtg...............................................esrtvthfhytgwpdh

FPPP-FELLEEIVDGIENYLSVS-KNRVAVLHCRMGKGRSGMITVAYLMKYLQ--------CPLGEARLIFMQARfkygmTNGVTIPSQLRYLRYHEFF
  || || | .... ....|. . |. . . ||..|.||.|.. .||||...         ..| ||   . . |      ..|. |.|.|.|.. ...
gvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR.....pgavqnpeqyrflyealle

0036941 (Phosphotyrosine protein) phosphatases II 152-253 3.7e-15 51.4 In-house 171-277 (297) alignment
Range on Protein: 152-253
Range on HMM: 171-277/297.0
VICERIGWLDHFPPP-FELLEEIVDGIENYLSVS-KNRVAVLHCRMGKGRSGMITVAYLM--------KYLQCPLGEARLIFMQARFKygmtnGVTIPSQ
 ..  .|| || .|. .. | .... ....|. . .. . . ||..|.||||.. .|.||        |. .... || . ... |.       |. ..|
thfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpg.....avqtleq

LRYLRYHEFFIT
.|.|.. ...  
yrflyeallell

0040438 (Phosphotyrosine protein) phosphatases II 151-254 1.6e-14 49.4 In-house 174-277 (317) alignment
Range on Protein: 151-254
Range on HMM: 174-277/317.0
NVICERIGWLDHFPPP-FELLEEIVDGIENYLSvSKNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARfkygmTNGVTIPSQLRY
. .   .|| || .|| ..|| .... ....|. ... . . || .|.||.|.. .||||     |. .. . ||   . ..|      ..|. |.|.|.
vthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqR.....pgavqtpeqyrf

LRYHEFFITH
| . ....  
lydalleylk

0045098 (Phosphotyrosine protein) phosphatases II 151-250 2e-14 49.1 In-house 155-269 (278) alignment
Range on Protein: 151-250
Range on HMM: 155-269/278.0
NVIC-ERIGWLDHFPPPFE---LLEEIVDGIENYLS------------VSKNRVAVLHCRMGKGRSGMITVAYLMKYL---QCPLGEARLIFMQARfkyg
.|     ..| || .|...    . |... |...|.             ... . . ||..|.||.|.. .||||..|   .. | ||   . . |    
gvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqR....

mTN-GVTIPSQLRYLRYHEF
  .  |....|.|.| . . 
.pglavqnleqyrflyefll

0043336 (Phosphotyrosine protein) phosphatases II 39-249 2.6e-14 48.8 In-house 68-273 (278) alignment
Range on Protein: 39-249
Range on HMM: 68-273/278.0
GLRLDISYI----------LVNLIVCSYPVNTYPKLLyRNSLDD----------------------------------LILFLTVYHgKGNFRIFNFRGE
| .|| .||            . |....| .  ..   .. . .                                   . .| ..| .... ..... .
ggdldsdYinAsyvdgynvprkfiatqgPlpetvedF.wrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeeh.lddytvrtlevt

KEDSDykdndligiaakfeskdfeiqelrstlindgkipispidletrtlveEETNNVICERIGWLDHFPP-PFELLEEIVDGIENYLSvSKNRVAVLHC
.  ..                                               |.   ..   .|| ||  | ...|| ...  . ..|. ..| . . ||
nlgdg...............................................esrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHC

RMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARfkygmTNGVTIPSQLRYLRYHE
. |.||.|.. ..||.     |..  .| ||   . . |      . |. |||.|.|.. .
saGvgRTGtfialyllleqlekeggvdleeavkelreqR.....pgavqtpsqyrflyeal

0040439 (Phosphotyrosine protein) phosphatases II 156-250 7.3e-14 47.4 In-house 147-243 (249) alignment
Range on Protein: 156-250
Range on HMM: 147-243/249.0
RIGWLDHFPP-PFELLEEIVDGIENYLSVS-KNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARfkygmTNGVTIPSQLRYLRYH
 ..| ||  |  || | .... ....|.   |. . . || .|.||.|.. .||||     |.|. .| ||   . ..|      ..|. |.|.|.| . 
ytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqR.....pgavqnpeqyrflyea

EF
..
ll

0047943 (Phosphotyrosine protein) phosphatases II 156-247 6.4e-12 41.0 In-house 173-266 (273) alignment
Range on Protein: 156-247
Range on HMM: 173-266/273.0
RIGWLDHFPP-PFELLEEIVDGIENYLSVS-KNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARFKygmtnGVTIPSQLRYLRY
  || ||  |  .| | |... ....|. . .| . | ||. |.||.|.. ...|.     |. .  . ||   . . |.      .|. |.|.|.| .
ytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpg.....mvqtpeqyrflye

0046845 (Phosphotyrosine protein) phosphatases II 145-248 9.7e-12 40.3 In-house 161-269 (284) alignment
Range on Protein: 145-248
Range on HMM: 161-269/284.0
VEEETNNVICERIGWLDHFPPP-FELLEEIVDGIENYLSV-SKNRVAVLHCRMGKGRSGMITVAYLMKYL--------QCPLGEARLIFMQARfkygmTN
 .|.    .   ..| ||  || .| | |... ....|.  ... . | ||. |.||.|.. ...|....         ... ||   . . |      .
tgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqR.....pg

GVTIPSQLRYLRYH
 |. ..|.|.. . 
mvqtleqyrfvyea

PTPc_motif_SM00404 167-228 2.8e-11 38.5 In-house 63-122 (140) alignment
Range on Protein: 167-228
Range on HMM: 63-122/140.0
FELLEEIVDGIENYlsVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARF
.. |....| |||    .|..  . ||..|  ||.....||||.| |. | ||  .. . | 
skyldkvldfiena..ekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerRp

subfamily_VSP_pd Subfamily VSP 154-251 2.9e-11 37.7 In-house 96-197 (212) alignment
Range on Protein: 154-251
Range on HMM: 96-197/212.0
CERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQAR-FKYG---MTNGVTIPSQLRYLRYHE
 .||   ||  | .| |  .   ....|.  ...| ..||. ||||.| |  |.|..  ..   .  | ..  |  ...   . .||  ||| ||. | |
vkriliddhnvpkleellvftkevkewlekdlknvlaihckGGkgrtGtivcalllaseifetakesldyfgerrtdktegekfqGvqtpsqkryvgyle

FF
  
qv

DSPc Dual specificity phosphatase, catalytic domain 169-229 9e-11 36.8 Pfam-A 58-116 (133) alignment
Range on Protein: 169-229
Range on HMM: 58-116/133.0
LLEEIVDGIENYlsVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFK
 |||.|. ||.    .|..  . ||..|  ||.....|||||. ...| ||  .. . | |
eleeavefieka..eqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrsk

DSPc Dual specificity phosphatase, catalytic domain 169-229 9e-11 36.8 In-house 58-116 (133) alignment
Range on Protein: 169-229
Range on HMM: 58-116/133.0
LLEEIVDGIENYlsVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFK
 |||.|. ||.    .|..  . ||..|  ||.....|||||. ...| ||  .. . | |
eleeavefieka..eqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrsk

0051429 (Phosphotyrosine protein) phosphatases II 144-235 1.3e-10 36.9 In-house 115-212 (272) alignment
Range on Protein: 144-235
Range on HMM: 115-212/272.0
LVEEETNNVICERIGWLDHFPPPfELLEEIVDGIENylsvskNRVAVLHCRMGKGRSGMITVAYLMKyLQCP--------------LGEARLIFMQARFK
  .|     .   ..|.||  |. | | |... . .      ..  . ||. ||.|.|.. ...|.  |. .              | ||.   ...| .
sagearevmhlhytdwpdhgvpq.eallellellld......ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpg

YGMTNG
.. | .
avqtee

0051299 (Phosphotyrosine protein) phosphatases II 155-245 4.9e-10 34.8 In-house 188-278 (288) alignment
Range on Protein: 155-245
Range on HMM: 188-278/288.0
ERIGWLDHFPPP-FELLEEIVDGIENYLSvSKNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARFKygmtnGVTIPSQLRYL
  ..| ||  |. .||| ...  . ..|. |.. . | ||. |.||.|.. ...|.     |   . . ||   . . |.       |. |.|.|..
hytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpg.....mvqtpeqyrfv

subfamily_Auxilin_pd Subfamily Auxilin 142-248 2.5e-09 30.1 In-house 59-160 (166) alignment
Range on Protein: 142-248
Range on HMM: 59-160/166.0
RTLVEEETNNVICErIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMK--YLQCPlGEARLIFMQARFKYGmtngvTIP
||  ... .. . | .||  .  |. | | |.   . ..|   ...| |.||  |.  |... .|.|.    |. |  .|  .|.  |   |       |
rtyrtaklssrvve.agwparraPnLeslvevcrnlyswlkkdpknvvvvhckDGraasavlvsallvfcrllsep.esavrlfsvkrlpig.....lsp

SQLRYLRYH
|. ||| | 
sekryleyl

subfamily_PTPMT1_pd Subfamily PTPMT1 151-227 6e-09 30.6 In-house 73-148 (171) alignment
Range on Protein: 151-227
Range on HMM: 73-148/171.0
NVICERIGWLDHF-PPPFELLEEIVDGIENYLSvSKNRVAVlHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQAR
.|   ..   |..  | .| ||. |. ||.. | ...|| | ||. |.|||. .  .||||  .. . ||  .  . |
gveqlqlatvDfteapdleklekgvefiekvas.kgkrvYv.HCkaGrgRsatlvacylmkkeklspeeAlkalkkkR

subfamily_DSP12_pd Subfamily DSP12 169-231 1.7e-08 29.0 In-house 67-127 (155) alignment
Range on Protein: 169-231
Range on HMM: 67-127/155.0
LLEEIVDGIENYLsvSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYG
 |.|.|| ||. |  ....  . || .|  ||  | .|||||. ...| .|  .  ... .  
hldeavdFieeal..eeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeie

subfamily_Auxilin_pd Subfamily Auxilin 42-102 2.8e-08 26.6 In-house 9-67 (166) alignment
Range on Protein: 42-102
Range on HMM: 9-67/166.0
LDISYILVNLIVCSYPVNTYpKLLYRNSLDDLILFLTVYHgKGNFRIFNFRGEKEDSDYKD
||||||   .|| |.|..   .  |.|..||. .||   | .... ..|. .......  .
lDisyitsriivmsfPaegv.estyknniddvrsfLesrh.pekylvynlsqrtyrtakls

0050432 (Phosphotyrosine protein) phosphatases II 157-228 3e-08 28.8 In-house 205-279 (308) alignment
Range on Protein: 157-228
Range on HMM: 205-279/308.0
IGWLDHFPPP-FELLEEIVDGIENYLsvsKNRVAVLHCRMGKGRSGMITVAYLM-----KYLQCPLGEARLIFMQARF
..| ||  || .| | .... ....|   .. . | ||. | ||.| . ...|.     |   . . ||   . . | 
tnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRp

subfamily_DSP14_pd Subfamily DSP14 170-226 8.7e-08 26.3 In-house 69-123 (157) alignment
Range on Protein: 170-226
Range on HMM: 69-123/157.0
LEEIVDGIENYlsVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQA
..|..| ||.     |.  ...|| .|  ||  ...|||||| .  | ||  .  .|
fdevadkieev..kkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksa

subfamily_PTPDC1_pd Subfamily PTPDC1 149-253 2.8e-07 25.2 In-house 80-176 (182) alignment
Range on Protein: 149-253
Range on HMM: 80-176/182.0
TNNVICERIGWLDHFPPPFELLEEIVDGIENylSVSKNRVAVlHCRMGKGRSGMITVAYLMKYLQCPLGEArLIFMQARfkygMTNGVTIPSQLRYLRYH
 ....   .|| |.  .. | . .||  ..   ......||| ||  |.|| |..  .||.   .    .| . .....     .. .   .|.. .. .
eqgiyvynfgwkDygvasleriLdivkvvaf..alqegkvav.hChaGlGrtGvliacylvyakrltaeka.iklvrsk....rpksiqtreqvelvkef

EFFIT
. |..
alfli

subfamily_RNGTT_pd Subfamily RNGTT 167-228 3.7e-07 24.0 In-house 94-155 (189) alignment
Range on Protein: 167-228
Range on HMM: 94-155/189.0
FELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARF
 |  .|.   .|.. . . ..|  .||  |  |.| . |.||..  .. . .|  .| .|| 
aeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRp

subfamily_DSP1_pd Subfamily DSP1 170-227 4.3e-07 24.2 In-house 81-136 (163) alignment
Range on Protein: 170-227
Range on HMM: 81-136/163.0
LEEIVDGIENYLSvSKNRVAVlHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQAR
.||... |..  . .. .| . ||..|  ||  . .|||||  .. | ||     | |
feeviefidevkk.knGkvli.hCqaGisRsstlclaylmktkrvsleeafdfvkqrR

subfamily_DSP23_pd Subfamily DSP23 147-219 8.8e-07 23.7 In-house 47-117 (148) alignment
Range on Protein: 147-219
Range on HMM: 47-117/148.0
EETNNVICERIGWLDHFPPPFELLEEIVDGIENylSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEA
| | |.   |..  |. ||  | ..|.|  .|.  . .||    .|| .|.||.| .   ||.|  .   .||
eatpnltlvrlriddyhppaleqvvefvrvvee..aeekneavsvhcllgrgrtgtmlacylvkerklaaaea

subfamily_DSP8_pd Subfamily DSP8 182-219 1.4e-06 21.9 In-house 89-126 (159) alignment
Range on Protein: 182-219
Range on HMM: 89-126/159.0
SVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEA
 .|.|   ..|.  |. ||  . .||.||.|.  | ||
aksengrvlvhvlaGisrsatvaiayimktlemsldea

subfamily_DSP6_pd Subfamily DSP6 183-219 1.4e-06 21.9 In-house 90-126 (158) alignment
Range on Protein: 183-219
Range on HMM: 90-126/158.0
VSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEA
 ||.   ..||  |  ||  .|.|||||.|.. | .|
rskkskvlvhClaGisrsvtvtlaylmkklalslnda

subfamily_DSP10_pd Subfamily DSP10 184-220 1.8e-06 21.9 In-house 90-126 (159) alignment
Range on Protein: 184-220
Range on HMM: 90-126/159.0
SKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEAR
.|..  ..||. |  ||  ...|||||.|.  | .| 
kkgsrvLvhCqaGisrsatvviaYlmkhlnlslnday

subfamily_DSP19_pd Subfamily DSP19 169-219 3.8e-06 21.3 In-house 74-122 (152) alignment
Range on Protein: 169-219
Range on HMM: 74-122/152.0
LLEEIVDGIENYLSVSkNRVAVlHCRMGKGRSGMITVAYLMKYLQCPLGEA
 |.|..| ||. .|   ..| | ||. |  ||  . .|||||  .  | ||
ylkealdFieearskd.gavlv.HCnAGvSRsasvviaylmkkeelsleea

subfamily_DSP3_pd Subfamily DSP3 172-219 4.3e-06 20.5 In-house 84-130 (162) alignment
Range on Protein: 172-219
Range on HMM: 84-130/162.0
EIVDGIENYLSVSKNRVAVlHCRMGKGRSGMITVAYLMKYLQCPLGEA
. .. |.. || .. .| | ||..|  ||  . .|||| . .  | ||
taakfidealsqkegkvlv.hcvvGvsRsatlvlayLmirrkmtlvea

subfamily_MKPLT_pd Subfamily MKPLT 189-220 6e-06 19.9 In-house 102-133 (164) alignment
Range on Protein: 189-220
Range on HMM: 102-133/164.0
AVLHCRMGKGRSGMITVAYLMKYLQCPLGEAR
 ..|| .|| ||  .|||.|.|. .  |.|| 
vlvhcvqGksrsssvtvafLikskgwtlkeay

subfamily_MKPLV_pd Subfamily MKPLV 189-220 6e-06 19.9 In-house 102-133 (164) alignment
Range on Protein: 189-220
Range on HMM: 102-133/164.0
AVLHCRMGKGRSGMITVAYLMKYLQCPLGEAR
 ..|| .|| ||  .|||.|.|. .  |.|| 
vlvhcvqGksrsssvtvafLikskgwtlkeay

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 171-230 7e-06 19.5 In-house 76-135 (154) alignment
Range on Protein: 171-230
Range on HMM: 76-135/154.0
EEIVDGIENYL-SVSKNRVaVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKY
.   . |.. . .| .|.| ..|.  |  ||  . ..|||. |. .| .|  .  ..|.. 
dkafefiddaiggvennkv.lvhsdkGvsrsaallisylmdklkislslalellkdsryii