Gene INP53 in Saccharomyces cerevisiae

Synonym: SJL3, SOP2, YOR109W, INP53

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP068_AA protein Get Run
ScerP068_AA_215-530 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Sac_COG5329 1-1080 0.0 1539.0 In-house 1-1070 (1070) alignment 
Range on Protein: 1-1080
Range on HMM: 1-1070/1070.0
MIIFVSEEPERRLAIVSNLYALVLKPVGKKPSDKPLCAIELLQKNDLKKYGFKRLTS-HEIFGVIGLIEVNGLLFVGAITGKSKVAQPCPGETVNKIFAV
|.|..||...|..||||| ||||......|.|....||.||.....|||.||..|.| |||.||.||||..|.||...|||||||||..||||..||.||
MkillsekktRsiaivsnkyalvfrrlsvknselsvcaaelvavselkkegfrslssaheiygvlGlielegslflivitgkskvaqvipgetiykilav

DFFCLNDNSWDFIEIDSsgypvlpETASTEYQDALpkHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQHSLSTDTYEEEYMWNSFLMQEMITYRDHL
||..||.|.||..||.|       ..||||....   |||.||||||||||||.|.|||.|.|||.|......||.||..||.||||||..|.|.||..|
dfislnnnkwddeeies.......deasteklrse..hpcselkkLlsngsFYfStdfditntLqkrlkeelelsvdtadeefmwnsflleelinyrskl

DTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQ-GTSLI
... ||.||..|||||||||||||....|||...|||.||..|.|||||||.||||||..|||||||||.|.||||||..|||.|||||.|||| ..|||
sslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDddGnvanFVETEqIvyssqycfsFtQvRGSiPiFWeqesnsli

NPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKKLNFnkdiFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSG
.|..|||||.||||..||||..|..||||.||.||||.|||||||||.||..||..|.|...    .||||||||||||.||. |.||.||| ..||..|
gpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekhlklsekpki....hlteFdfhketsqdgfddvkkLlplieqdllefg

YYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLaafRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSL
|.||||.|.|.||||.|.|||||||||||||..||.||.   |..||.||.|...|.|||.||..|.|.||||.||.||||||||.||||||.||||.|.
yfsydvkegkliseQdGVfRtNClDCLDRTNviQqlisk...rvlleqfrsikvisaiddedflqklneLWadnGDaisqiYTGtgalkssftrkgkrsi

AGALSDATKSVSRIYINNFMDKEKQQNIDTLLGRLPYQKAVQLYDPVNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNGATKKVDLSKWLFPIGEKFKPD
|||||||||||||.|||||.|||||..||.|||.||.|.||.||||.||||   |.... .||  .|...  ..||.|| ... .|.|.|....||....
agalsDatkSvsRmyinnfvDkekQdaidllLgklpdqeavelydpineyvnlrlrkseseftaaknvsiftltfnsngessstkllklllkvlekkisk

IVVLGLQEVIELSAGSILNADY----SKSSFWENLVGDCLNQYDDKYLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEY
.||.. ...... ...||....    .|....||||... |....|.|. ...|.|.|.|||...||....|.....|..|||..|...|||||.|..|.
lvvgvvglqkqiwlelillssltksefkeeeeenlvrkyenklkkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaes

GATSFCFVNSHLAAGATNVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEEGYIDKLLHFDQLTLGINSGSVFEGFKE
....|.||....|....|..||.|.||||.........|||..|..|.. ...|..|....|.||.|  ........|......|| ......|.|....
eglvfifvdasaaledenesernskyesitkrvskeipkmikdhqlilldiainltidydeeevraekekeidrelkkydtkqeltekvfvekvleptev

PTLKFRPTYKYDPGTGTYDSSEKERTPSWTDRIIYKGENLLPLSYSDAPIMISDHRPVYAAYRAKITFVDDKERLSLKKRLFTEYKQEHPEEPGSLISDL
|.|.....|..|..|.|.|...|.||.........|.|...................|..|...|......|..||||....||...|.||||..|.|.|
pellekksyeddndtdtedayrklrtrkliqkeekktelaysslelkisdhkpvtaevkiavlskdekkklklelslkiayktekpselpeepdelssal

LSLDLDNKSTDGFKSSSESSLLDIDPIMAQPTASSVASSSPVSSASASLQPVRTQNSSQSRTPIKKPVLRPPPPPAHKSVSAPAPSTSKEKSPTPQTSTA
||.||...|.|..|.|....|.|.|..||||.|....||...|...|||.|.|.||.|......|||...........|...|.|..||..|.....|.|
lskdlekisldatkqskvvklvdlddtmaqpkalpsksseqpsepeaslrpsrsqnksklnvepkkpstskqnkekkssllspipeiSkvssslrkgssa

SLSSVTKNIQENKPLAQNRRIPPPGFSQNILTPKSTSNLASPMSSKVDLYNSASESTRSAQDARQQTPTAFAASRDVNGQPEALLG
||.|.||.|...||.........|...|..|.|||||..|.....|||..||......|..||.|.|.|..|||.....|.||.|.
slasetksipkkkpkvtklslskpvslqkllspkstskeaidnakkvdrvnspirrksskadaeqststklaassetedqeeakls
subfamily_INPP5F_pd Subfamily INPP5F 2-977 0.0 1520.9 In-house 9-951 (951) alignment 
Range on Protein: 2-977
Range on HMM: 9-951/951.0
IIFVSEEPERRLAIVSNLYALVLKPVGKKPSDKPLCAIELLQKNDLKKYGFKRLTSHEIFGVIGLIEVNGLLFVGAITGKSKVaqpcpgetvnkifavdf
.|....| ||.|.|||. ..|.|.||.||.|.|...|||...|.||.....|.|...|..|.|||||..| ..|..|.|||||                 
killvseeerkLvivsessilgllpvqkkeskkevvaiervakldlsekdskelekeectgliglielegkiivatiegkskv.................

fclNDNSWDFIEIDSSGYPVLPETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQHSLSTDTYEEEYMWNSFLMQEMITYRDHLDT
   |...||.|.||||||..|.|.........|.|....|||||||.||||||.|||||.|||.||. ..| |||...|...||.||....|.|||.||.
...nnkkwdlididssgylqlkeekeqneeeklekrlleelkkllsdgsFYysldfDltntlqkrgleeksestddwderFfWNkfllkdlinyrdkldk

NlkqilddegFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQGTSLINPR
.         |||.||.||.||......||||.||.||..|.|||||||..||.||..|||||||||.|.....|...|||||||.|||||| .....|.
e.........fltpviqGfvetkeisieklkvsltlisrrSrkragtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvfweqsgkkykpk

VQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKklnfNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYS
..||||.|.|||.||.|......|||.|..|||||.||||..|||.|||.|....    .||.||..||||.|||.|.|. |.|||.|| ......||.|
ikitrseeetqpaFdehfkeqlkkygkvvivnllsqkssekklskaykeqllkle....skdvflikfdfheetsgekfenvsklielikneikevgyfs

YDVREkKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGA
|||.| |.||||.|.|||||||||||||..||.||.|.....||...|....|.|||.....|...||||.||.||..|.||||||....|||...|||.
ydvke.kviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfepessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGv

LSDATKSVSRIYINNFMDKEKQQNIDTLLGRLPYQKAVQLYDPVNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNGATKKVDLSKWLFPIGEKFKPDIVV
|.|..|||||.|.|||.||..|..||.|||.||.|..|.|.||..|.....|.....|||.|||||||.||.||||..||.||||.|||||||||||.||
lkdgyksvsryylnnfkdkyrqkvidlllGklpkqevvelidpkkeekeeelrekeekftetsninllvgsvnvngsskkadlskllfpigekfkpDlvv

LGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQY--DDKYLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSF
||||||.||.|||||.||||||.|||.||.|.||..  ..|||.||.||..|||.|.||..||||.||.|||.||||||.|.|||||||..||||.||||
lGLqEvvELtaGsiLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfeysatsF

CFVNSHLAAGATNVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEegyIDKLLHFDQLTLGINSGSVFEGFKEPTLKF
|||||||||||.|||||||||..|.|.|||.|.|.|..|||||||||.||||.||||.||||||.||   |||||..||||  |..|.|||||||.||||
cfvnsHlaAGasnveeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqe...idkLleyDqLtkeieaGevFegfkEetlkF

RPTYKYDPGTGTYDSSEKERTPSWTDRIIYKGENLLPLS-YSDAPIMISDHRPVYAAYRAKITFVDDKERLSLKKRLFTEYKQEHPEE----PGSLISDL
|||||||.||..||.|||||||.||||||||||.| .|. ||||.|.||||||||||.|||.|.||.|..|.|||.|..|||.|..|.    ...|.|| 
rPtYkyDlgtknYDtsekeRtPaWtDRiiykgevledLeyysdaeilisDHrPvyaafrakvtvvDekkkltLkkklyeeykeeleeasdsekdellsdd

LSLDLDNKSTDGFKSSSESSLLDIDPIMAQptaSSVASSSPVSSASASLQPVRTQNSSQSRTPIKKPVLRPPPPPAHKSVSAP
|... ...|.|....|.|..|||.||..||   .|..|.|...|.||....|.....|.|..|.||.|.|||.|.|.|.|..|
lekkeeaesldkivesaelklldldpkraq...dssssvskllsgsakqvkvvldvdsasvspdkkkvvrppepeaeklvkep
subfamily_Synaptojanin_pd Subfamily Synaptojanin 138-830 2e-168 553.2 In-house 62-750 (754) alignment 
Range on Protein: 138-830
Range on HMM: 62-750/754.0
PCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQHSLSTDTYEEEYMWNSFLMQEMITYrdhlDtnlkqiLDDEGFLTTVIRGFAETFVSYVKKLKVALTI
   ||||||. |.||.||  | .|.|.     |.. .... .. ..||  |   .  .    .      .. . .|. |..|  |  . |. . ..  ..
riielkkllasgtfyfsssadsasrldlslsaqrrkqeesednrffWnrslhlhlqrf....g......vncddWllkvmcGsveirtvyagakqakaal

ISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQ-GTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLS
||. | .||||||| |||.|| ||||||||| ...  .   .| |||||.|.|||| |    . .|...|.|||... ||.|. .  |.|| | .|||| 
isrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirGsvPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnllG

TKSSEIELSKRYKEHLTHSkklNFNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDS-LLSSGYYSydVREKKNISEQHGIFRTNCLDCLDRTNLAQQII
.| .|  ||| .|.||..|   ...||.   .||.|... ..  . ..||.  .|   | | ....   ..|.  .||.|. |.||||||||||  | ..
skegeevlskafkkhlkas...ehakdvpfvkfdyhqkvkggkkeklekllkkqlklflesasffl..skgkevekeqtGvlrvnClDCldrtnavqtvl

SLAAFRTFLEDFRLISSNSFIDddDFVSKHNTLWADHGDQISQIYTGTNALKSSfSRkgkmslAGALSDATKSVSRIYINNFMDKEKQQNIDTLL-G---
.|.   . || ..| | .| ..   |   ...||   ||.||.||.|| ||... ..      .. | |...||.|   |||.|  ||. || || |   
glevlekqlealklsskesvvs..rfeevfkslWsknGdeiskiyaGtgalegk.ak......vsklkdgarsvartiqnnfldsskqeaidllllgnty

-RLPYQKAVQLYDPVNEY----VSTKLQSMSDKFTSTSNINLLIGSFNVNGA-------TKKVDLSKWLFPIGEKF------KPDIVVLGLQEVIELSAG
     .|| .| ....      .  .|   . ..|..... ...|..||||        .|.  |..||. . |.         ||. .|..|...|.|.
veeladkarallkssllrasakilkelvereqelteakklricvgtwnvnggkqlrsvalknesltdwlldlpelsgaedskpadiyaiGfeelvdlnas

SILNADYSKSSFWENLVGDCLNQyDDKYLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSFCFVNSHLAAGATNV
 ...|  ..   | . .   | . | || ||  ||.  . .  ||... . ... |  .| |||. | |||||||.||.   .||.||. |||||| ..|
nlvsasttnrkewaeelqkvlsr.dakyvlltseqlvGvclfvfvrpklvpfirdvavstvktGlgGaaGnkGavairlllhstslCfiCshlaagqskv

EERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEegyIDKLLHFDQLTLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYD
.||  ||. | | |.|   ...  || .|||||.||||.|....|.. . ...    |||...||||   ..| ||.||.|..|.| ||||||  .  ||
kernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkkkd...ydklvendqltkqkkkgkvfkgfaegeltfaPtykydlfsddyd

SSEKERTPSWTDRIIYK
 ||| |.|.||||....
tseklrvPaWtdrvlwr
subfamily_SAC1_pd Subfamily SAC1 59-533 4.3e-99 323.2 In-house 6-453 (458) alignment 
Range on Protein: 59-533
Range on HMM: 6-453/458.0
EIFGVIGLIEVNGLLFVGAITGKSKVAQPcPGETVNKIFAVDFFCLNDNSWDFIEIDssgypvlpETASTEYQDAlpkhpcyeLKKLLSNGSFYYSSDFD
.|.|..|.|..    ..  || |..|..   |......  |.   .. || .  | .        ... .||..         |...|.. .||.| ..|
kiagilGiikLlsgkylivitkkeevgri.ngkviyrvadveiipvkknslslteeq........kkeekeylkl........lelvlksetfYfsytyd

LTSTLQHRGYGQHS-----LSTDTYEEEYMWNSFLMQEMITyRDHLDTnlkqilddegFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNAR
||..||..   ...      . .. .| ..||. |.... . ...|..          |.  ||.||...    ... .. ...||. | .|||||.. |
ltnslqrlekvtsaalkerslleradeRffwnkhlledlrk.epeles..........filPvikGfikikelslnakeikfilisRRsifRaGtRyfvR

GVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQGTSL-INPRVQITrSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEhL
||| | ||||||||| |.  ..   .| |.|||||..|.|  .| . |.|... . | ..  |.||. . .|.||.  .|||.  | || .| ..|.. .
GvdkeGnvanfvEtEqiveaekaltsFvqvRGsiPllWsqkpnLkykPkvkls.esedsldafkkhldeqielygenvlvnLvdqkGsEkklgeayes.v

THSKKlnfNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYdVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISS
.....   .|.|  . |||||| ..  .  . .||  . . | . ||..   .||| ..||.|..||||.|||||||. | ...  . .. || . ....
vraln...kkkikyvafDFHkeCrkmrwdrlklLidqlekelsqegyflk.seekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlat

NSFIDD-DDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDTLLGRL
.| ..| ... ...  ||||..|..|. |.|| |||. | |.|| .| ||| | ..|||| |.|||.|.|.|. || .||..
eskledsaeletsfknlwadnadavsvqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgky
Syja_N SacI homology domain 60-381 2.2e-95 310.5 Pfam-A 1-318 (319) alignment 
Range on Protein: 60-381
Range on HMM: 1-318/319.0
IFGVIGLIEVNGLLFVGAITGKSKVAQPCPGETVNKIFAVDFFCLNDNSWDFIEIDSsgypvlpetaSTEYQDALPKHPCYELKKLLSNGSFYYSSDFDL
..|..|||...   ..  ||...|||.. ..... ||  |.|..||.....  .|..          ..| ...  .... .||||||.||||.| |.||
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaiee..........ekeeeekeeekllkllkkllssgsfYfSydyDl

TSTLQHRGYGQHSLST---------DTYEEEYMWNSFLMQEMITYRdhldtnlkqiLDDEGFLTTVIRGFAETFVSYVK-KLKVALTIISKQSWKRAGTR
|..||..   ... ..         . ..|...||..|....|...          ||.. .|...|.||.|.   .|| | || ||.||..|.||||||
trslqrksekeeeekeeeskslpllkevderFvWNrnllkplielk..........ldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtR

FNARGVDDEANVANFVETEFIMY-S---SQYCYAFTQIRGSIPVFWEQ-GTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIEL
...||.||..|||||||||.|.. .   |.....|.|||||.|.||||  .  ..|...|||| ||.|..|.||. | ...||...|||||..|..| .|
ylrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnlslkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkL

SKRYKEHLTHS-KKLNFNKDIFLTEFDFHKETSQEGFS
|..|.|....  |||. .|.. ..|||||||.....|.
seayeelinklnkklkekkklkyiefDfhkeckgkkfe
Syja_N SacI homology domain 60-381 2.2e-95 310.5 In-house 1-318 (319) alignment 
Range on Protein: 60-381
Range on HMM: 1-318/319.0
IFGVIGLIEVNGLLFVGAITGKSKVAQPCPGETVNKIFAVDFFCLNDNSWDFIEIDSsgypvlpetaSTEYQDALPKHPCYELKKLLSNGSFYYSSDFDL
..|..|||...   ..  ||...|||.. ..... ||  |.|..||.....  .|..          ..| ...  .... .||||||.||||.| |.||
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaiee..........ekeeeekeeekllkllkkllssgsfYfSydyDl

TSTLQHRGYGQHSLST---------DTYEEEYMWNSFLMQEMITYRdhldtnlkqiLDDEGFLTTVIRGFAETFVSYVK-KLKVALTIISKQSWKRAGTR
|..||..   ... ..         . ..|...||..|....|...          ||.. .|...|.||.|.   .|| | || ||.||..|.||||||
trslqrksekeeeekeeeskslpllkevderFvWNrnllkplielk..........ldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtR

FNARGVDDEANVANFVETEFIMY-S---SQYCYAFTQIRGSIPVFWEQ-GTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIEL
...||.||..|||||||||.|.. .   |.....|.|||||.|.||||  .  ..|...|||| ||.|..|.||. | ...||...|||||..|..| .|
ylrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnlslkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkL

SKRYKEHLTHS-KKLNFNKDIFLTEFDFHKETSQEGFS
|..|.|....  |||. .|.. ..|||||||.....|.
seayeelinklnkklkekkklkyiefDfhkeckgkkfe
subfamily_FIG4_pd Subfamily FIG4 149-539 2.4e-60 195.5 In-house 140-547 (569) alignment 
Range on Protein: 149-539
Range on HMM: 140-547/569.0
GSFYYSSDFDLTSTLQHRGY-----GQHSLSTDTYEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISKQSW
  ||.|  .||| |||.  .      ... ..|. . .   .   ..|. .. ..|   ||.... . .| ..| || .     |   .. .|.|...| 
knfyfsysydltrtlqtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkdtvktfdWlleiihGfvsqskisvlgksiyvtliarrss

KRAGTRFNARGVDDEANVANFVETEFIM-------YSSQYCYAFTQIRGSIPVFWEQGTSLINPRVQITrsFEATQPVF---DKHIMKSVEKYG-PVHVV
| ||.||  |||. . .||| |||| |.       ..|.   .|.|.|||.|..|.| .| . .. .|.   . ..| .     |. . ...|| |. ..
kfaGarflkrGvnnkGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpik..idvvdPfasaaalhfddlfqryGspiiil

NLLSTK---SSEIELSKRYKEHLTHSKK-LNFNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDvREKKNISEQHGIFRTNCLDCLDRT
||. .|     |  |.. ... ..   . |  .| .  ...|... . ... . ...|  .  .|.   |..    .. .    |.|| ||||.||||||
nlvkkkekrkresilleefeaaieylneflPeekklkyiswdmaraskskeenvlevlekyaeksvkktGiflsa.pdlestkiqeGivrtnCvdcldrt

NLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDT
| || .|.  |..  |... .| . ..  | | |   . |. |.||...  |.|..  ..  . .   ...   .|  ....| | | |.|..||. |. 
naaqfvigkvalgyqlkslGiidesklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainl

LLGRLPYQKAV
.||   .....
flGvyspregl
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 571-849 7.3e-28 88.0 Pfam-A 1-249 (249) alignment 
Range on Protein: 571-849
Range on HMM: 1-249/249.0
GSFNVNG-------ATKKVDLSKWLFPIGekfkPDIVVlgLQEVIELsagsiLNADYSKSSFWENLV---GDCLNQYDDKYLllrveqmTSLLILFFVKA
...||.|       | |. .| ..|  ..    ||...  |||| |       . .. . .....|     .  .... ...           . ...| 
ltwNvlgwnarsdrakkldqladllqsed....pDvll..LQEvded.....plsellatglaselgldgdgksggggggda.......gggglallsky

DKAKYVKQVE---GATKKTGFRGMAGNKGAVSIRFEygATSFCFVNSHLAAGATNVE--ERrSDYESIVRGITFTRTKmiphhdSIFWLGDMNYRINLPN
. .|.....    |..    .|.. ||||.|..||.   .....||.||..|  . .  ||  ... | .  .. | .      .....||.|.|...|.
pldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaeidkladdsrgs......pvilaGDfNsrpdspd

edvrrellnqeegyidkllhfdqltlginsgsvfEGFKEPTLKFRPTYKYDPGTGTY-------------DSSEKERTPSWTDRIIYkgE---NLLPL-S
                                  .|| |.  .|.|....| |.  .             |..|| |.|...|.|..  .     | . .
..................................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilv..ssgwpalvvsg

YSDAP-IMISDH
.|  . .. |||
asllsdrggSDH