Gene SSH in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily Slingshot
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP026_AA protein Get Run
SpurP026_AA_495-640 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Slingshot_pd Subfamily Slingshot 480-646 7.3e-89 289.6 In-house 1-167 (169) alignment
Range on Protein: 480-646
Range on HMM: 1-167/169.0
YKRFIDKQILLICGQLDSASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKAL
|| |||...|.| ||||||||||||.|||||||||.|.||.|||| ||||.|||.||||||.|.|.|||.||. |.|||..||.|| |..|||..|||.|
ykefidnemlvilgqldsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvl

VHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILEASRQRHTMF
||||||.||||||||||||||||..|| ||..|| .||.|.||..|.|||..||||||||.|||...
vhckmGvsrsastviayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGileaskqrhnkl

subfamily_DSP1_pd Subfamily DSP1 497-637 1.7e-44 145.8 In-house 17-157 (163) alignment
Range on Protein: 497-637
Range on HMM: 17-157/163.0
SASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
   || |..||||| .||.|. |...|.  |||..||.||.|.. |.| .. | |  ..|.  ....   |. ..|... | |.||..|||||.. ..||
PvekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclay

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILE
 ||.  ..|| | |||| .||||.|| .|..||  ||  |.
lmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll

zf-DHHC DHHC palmitoyltransferase 62-213 1.3e-41 128.2 Pfam-A 2-156 (174) alignment
Range on Protein: 62-213
Range on HMM: 2-156/174.0
INFLLATFVDPGVFPRT--AVGDEDRDDDLRAPLYKTVQIRGIQVRMKWCSTCRFYRPPRCSHCSVCNNCIERFDHHCPWVNNCVGRRNYRYFFLFLLSL
. ..|..|.|||..||.  .   | ..|.      .  .  . . . ..|..|....|||. ||..||.|. .|||||||||||.|.||..||.||||.|
ssyiltyftdPgyvprssqdesneeeedkeekqraiqteaelknnekrfCkkCqiikpprshHCriCnkCvlkfDhHCpwvnncIGarNhkyFllfllyl

TMHMVSVFVLSLIYVLQAKASISDYQKIISSVTN-TYTWPVYGPLLAFGICLCLV
|. .| ...|||.....   . .  .  | |. .  ..  .   .|.| ..|...
tlllvialllslrifvryvlltkqssvniisnlskillvvisaiallfllallaf

subfamily_DSP10_pd Subfamily DSP10 498-639 1.5e-41 135.9 In-house 14-156 (159) alignment
Range on Protein: 498-639
Range on HMM: 14-156/159.0
ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPE-RFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
||... ...|||| .|.||| |.. .. ..||.|... |.| |  .||  | . |  ...| ....  . |. .|.. ||. ||||. ||||||. ||||
asqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaY

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILEAS
 ||. ...|. | .||| ||.|| || .|| ||  .|  |. |
lmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks

subfamily_DSP19_pd Subfamily DSP19 498-635 3e-38 125.5 In-house 12-149 (152) alignment
Range on Protein: 498-635
Range on HMM: 12-149/152.0
ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYA
.... ...||||   |.| ..|.|... .|||.. . .|.||. |.|..| ..|. |.|||......  |. .|...    ||||. |.||||| |||| 
vgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviayl

MKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI
||.  ..||.||. |. .|  |.||. |.|||. ||  
mkkeelsleealelvrearpcikPneGFikqLkeyeae

PTPc_motif_SM00404 498-633 1.7e-37 123.4 In-house 2-138 (140) alignment
Range on Protein: 498-633
Range on HMM: 2-138/140.0
ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDN-FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
 |.| .|.||||. .|.... |...|. ...|.|.|...    ..|....| | |. ...|..... .. |...|.. | | ||||..|.||||. .|||
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
 |......|. |..||| .|.||.||  |..||. ||
lmryrqlslaeayefvkerRpiispnlnfvrqLieye

0044763 (Phosphotyrosine protein) phosphatases II 492-637 3.8e-37 123.0 In-house 17-171 (178) alignment
Range on Protein: 492-637
Range on HMM: 17-171/178.0
CGQLDSASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPER---------FKYCNIRLYDDVEEDLLNHWNTTYLFLSKAK-EAGSKALVH
...   ||.|....|||| ..|.||. | |.|...|.|.|.|. ..|..          ..|..| . |. . ||| |.  .. |. .|  | |.. |||
rsdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVH

CKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKRSiIRPNDAFMKQLQVYEGILE
|..|..||.. |.|| ||..|..|| |...|. .|. | ||. ...||. .| .| 
CsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrll

subfamily_DSP6_pd Subfamily DSP6 499-638 9.2e-37 120.0 In-house 15-156 (158) alignment
Range on Protein: 499-638
Range on HMM: 15-156/158.0
SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPE--RFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
 .| ...||||. .||.|. |.. .. |.||.|.. .|.| |   .|| .| . | ....| ...  .  |. .|... || ||||  |||||   ..||
veilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlay

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILEA
 ||.. ..|. | |.|| ..| | ||  ||.||  .|  |. 
lmkklalslndaydlvkkrksnisPnfnfmgqlldferslrl

subfamily_DSP14_pd Subfamily DSP14 496-640 1e-34 113.8 In-house 5-148 (157) alignment
Range on Protein: 496-640
Range on HMM: 5-148/157.0
DSASKIFDHIYLGsEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIA
 . |.| ....|.    |.. ..|.....  |.|.| |  |   . ... .... |. |..| .|.....  . ..|..| |.||||..|.||||| ..|
aalsqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslcla

YAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILEASR
| ||   ..|. |   || .|.|||||  | |||. ||  |... 
ylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgks

0048179 (Phosphotyrosine protein) phosphatases II 499-636 1.2e-33 111.2 In-house 5-144 (144) alignment
Range on Protein: 499-636
Range on HMM: 5-144/144.0
SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERF--KYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
|.|....|||| . |.||..| ..|.....|.| |... |.||.  .|... . |    |||....... |. .| | | . ||||..|..|... |.||
seilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaay

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGIL
 ||..|..|| ||..|. .|... ||. ....|. || .|
lmkklglsleealalvrsrrpgavpnpgqlrfLleyekll

0048076 (Phosphotyrosine protein) phosphatases II 498-635 1.4e-33 111.0 In-house 4-141 (145) alignment
Range on Protein: 498-635
Range on HMM: 4-141/145.0
ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYA
.|.|....|||| ..|.||..|...|....||.| |....... ..|... . |  . |||... . . |. .| ..| . ||||..|..|... |.|| 
pseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl

MKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI
|...|..|| ||..|. .|... ||. ....|. .| .
mlllgvsleealelvrsqrpgavpnpgqlrflyefele

subfamily_DSP12_pd Subfamily DSP12 499-636 4.6e-33 108.8 In-house 3-143 (155) alignment
Range on Protein: 499-636
Range on HMM: 3-143/155.0
SKIFDHIYLGSEWNASDLDELEENGVGYILNITKEC-DNFFPER--FKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIA
|.| . .|||.  .. . . |.| ..  .| ..||  ... ...   .. .| ..|. |||.|.| ...  |...| | . . ||||..|.|||...|||
srilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviA

YAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGIL
| ||.... || ||..|| |.. |.||. |..||...| . 
YlmkkeklslekAlklvkekkpeiepNegFleQLklfekmg

DSPc Dual specificity phosphatase, catalytic domain 505-633 5.4e-33 108.7 Pfam-A 1-131 (133) alignment
Range on Protein: 505-633
Range on HMM: 1-131/133.0
IYLGSEWNASdLDELEENGVGYILNITKECDN---FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEY
.||||. .|| |. ||..|. ...|.|||..|   . .....| .| . |. |... .. . .. |..||.. | | ||||..||||||. .||| ||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

GMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
...|. |..||| .||.|.||. |..||  ||
nlslneAyefvkerrskispnagflrqLleye

DSPc Dual specificity phosphatase, catalytic domain 505-633 5.4e-33 108.7 In-house 1-131 (133) alignment
Range on Protein: 505-633
Range on HMM: 1-131/133.0
IYLGSEWNASdLDELEENGVGYILNITKECDN---FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEY
.||||. .|| |. ||..|. ...|.|||..|   . .....| .| . |. |... .. . .. |..||.. | | ||||..||||||. .||| ||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

GMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
...|. |..||| .||.|.||. |..||  ||
nlslneAyefvkerrskispnagflrqLleye

subfamily_LRR-DSP_pd Subfamily LRR-DSP 492-636 7.4e-32 104.5 In-house 114-258 (263) alignment
Range on Protein: 492-636
Range on HMM: 114-258/263.0
CGQLDSASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDV-EEDLLNHWNTTYLFLSKAKEAGSkALVHCKMGISRSA
  .    ..| |...||.   | .   |...|| .||    ... .||. |||  |   .|| | |. .|.. |  |. . .. |   ||||. |.|||.
tlvssvPdeiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrss

STVIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGIL
. ||.| ||   .... |||.|. ||. |.||  |..||. ||  |
tlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekkl

0049772 (Phosphotyrosine protein) phosphatases II 501-650 9.1e-32 106.4 In-house 150-287 (314) alignment
Range on Protein: 501-650
Range on HMM: 150-287/314.0
IFDHIYlgSEWNASDLDELEengvgyilnitKEC--DNFFPER-FKYCNIRLYDdVEEDLLNHWNTTYLFLSKAkEAGSKALVHCKMGISRSAS-TVIAY
|.|  .  .|..|.||..|.           .|.  ...|... .||..| ..|  ...||....  . |. .| ..|.. |||||.|..|...  |.||
ildgng..neptaadlellk...........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaay

AMKEYGMTLEYALDFVKGKRSiIRPNDAFMKQLQVYEGILEASRQRHTMFRSKS
 || .|..|| ||..|. ||. |.||. |..||. || ||||....  ......
lmkllgvsleealedvrlkRp.inpnpgfieqleqyefilealleylkflkkfy

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 499-633 1e-31 103.5 In-house 8-144 (148) alignment
Range on Protein: 499-633
Range on HMM: 8-144/148.0
SKIFD-HIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERF-KYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
|.| | ...|||   |.||. |.. ||  | | |||.|| . .|  .| ...| |. .|||   ...   |..|||..| . |||..||.|||.  ....
seikdafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallw

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
 ..   ..|. ||..|| ||  ..||  |.|||. .|
lidfkrvslkealalvkskrryvdpnlgfLkqLaele

subfamily_DSP8_pd Subfamily DSP8 498-637 1.6e-31 103.0 In-house 15-155 (159) alignment
Range on Protein: 498-637
Range on HMM: 15-155/159.0
ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDN-FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY
  .| ...||||. .. . . |...|..|.||. ..| .  . .  |.  . . |. .|.||. ..... |. |||.. .. |||.  ||||||. .|||
ptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiay

AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILE
 ||.  |.|. |  ||| ||  | ||  |..||  ||  |.
imktlemsldeayrfvkekrptispnlnflgqLleyekelk

0041856 (Phosphotyrosine protein) phosphatases II 498-636 6.2e-31 102.8 In-house 19-172 (182) alignment
Range on Protein: 498-636
Range on HMM: 19-172/182.0
ASKIFDHIYLGSEWN--------------ASDLDELEENGVGYILNITkeCDNFFPERF-----KYCNIRLYDDVEEDllnhWNTTYLFLSKAKEAGSKA
 ..| ...|||| ..              |..|. | |.|...|.|.|  ... .||..     .|...   |.   |    ..... |. ...| | . 
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt..eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpv

LVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKRS--IIRPNDAFMKQLQVYEGIL
||||..|..|... |.|| ||..|..|| |...|. .|.  .|.||  |. ||...| .|
lVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallelll

subfamily_MKPLT_pd Subfamily MKPLT 503-635 2.4e-30 99.2 In-house 27-159 (164) alignment
Range on Protein: 503-635
Range on HMM: 27-159/164.0
DHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYG
|..|||   .| .   |..  . .|.|...|. . ||. ..| .... | ..| | .. . .  ||..| ..| . |||| .| |||.|. .|. .|  |
dtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskg

MTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI
 ||. | ...| .|||..||  |.|||  .| .
wtlkeayeylkerrsivapnrGflkqlakfeel

subfamily_MKPLV_pd Subfamily MKPLV 503-635 2.4e-30 99.2 In-house 27-159 (164) alignment
Range on Protein: 503-635
Range on HMM: 27-159/164.0
DHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYG
|..|||   .| .   |..  . .|.|...|. . ||. ..| .... | ..| | .. . .  ||..| ..| . |||| .| |||.|. .|. .|  |
dtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskg

MTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI
 ||. | ...| .|||..||  |.|||  .| .
wtlkeayeylkerrsivapnrGflkqlakfeel

0043147 (Phosphotyrosine protein) phosphatases II 499-636 1.3e-28 95.3 In-house 20-160 (172) alignment
Range on Protein: 499-636
Range on HMM: 20-160/172.0
SKIFDHIYLGSEWNASDLDELEENGVGYILNITKE---CDNFFPERFKYCNIRLYDDVEEdLLNHWNTTYLFLSK--AKEAGSKALVHCKMGISRSASTV
 ..... .....  |.... | |.|...|.|.|..   ....... ..|. .  .|     ||...  .. |. .  |.. | . ||||..|..|..  |
drfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlv

IAYAMKeYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGIL
.|| |. .|..|| |...|. ||... .|. ....|. .| .|
aaylml.lglsleeavalvrekRpgavqnpsqyrflyyfekll

subfamily_DSP3_pd Subfamily DSP3 497-636 2.6e-28 92.7 In-house 10-157 (162) alignment
Range on Protein: 497-636
Range on HMM: 10-157/162.0
SASKIFDHIYLGSEWNASDLDELEENGVGYILNITKE-------CDNFFP-ERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEA-GSKALVHCKMGIS
..  .....|.| |  |.| ..|.. |. ..|| ..         ..|.    .||. . . |  | || ....|.  |. .| .   .| ||||..|.|
evdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvs

RSASTVIAYAMKEYGMTLEYALDFVKGKRSIiRPNDAFMKQLQVYEGIL
|||  |.|| |    |||  |.  |. ||.| .||. |.|||. ..  |
RsatlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeel

0049260 (Phosphotyrosine protein) phosphatases II 500-636 2.1e-26 87.8 In-house 10-149 (152) alignment
Range on Protein: 500-636
Range on HMM: 10-149/152.0
KIFDHIYLGSEWNASDLDELEENGVGYILNITKECDN---FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSK-AKEAGSKALVHCKMGISRSASTVIA
..  ....|... |.... | |.|...|...|.....   .... ..|...   |.   ||  .    .||. | |.. | . ||||. |..|..  |.|
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaa

YAMKeYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGIL
| |. .|..|| |...|. ||... ||  ....|. .|..|
ylml.lgvsleeavalvrekRpgavpnpgqlrflyefekll

subfamily_DSP15_pd Subfamily DSP15 499-635 4.6e-26 85.7 In-house 3-138 (151) alignment
Range on Protein: 499-635
Range on HMM: 3-138/151.0
SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPErFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAM
||.   .|||   ...| . |.|. .  ||..  .  ..... ..|  |.. |  . .| .. . .  |. |..  . . |||| .|.|||.  |.|| |
skvlpglylgnfrdskdeelLkeknithilsvhdnakkllkd.ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlm

KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI
    .  . ||...| .||.  ||  | .||..||  
tvtelnwrdalevikaaRsvanPnfGfkrqlkeyekt

0046846 (Phosphotyrosine protein) phosphatases II 497-634 6.6e-26 86.5 In-house 11-170 (176) alignment
Range on Protein: 497-634
Range on HMM: 11-170/176.0
SASKIFDHIYLGSEW----------NASDLDELEENGVGYILNITKE-------CDNFFPE----RFKYCNIRLYDDVEEDLlNHWNTTYLFLSKAKEAG
. . | ....||| .           |..|..| |.|.....|.|.|       |.|..||     ..|...   |    || ... . . |. .| ..|
dldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeg

SKALVHCKMGISRSASTVIAYAMKE-YGMTLEYALDFVKGKRS-IIRPNDAFMKQLQVYEG
 . ||||..||.|..  |.|| ..  .|...| ||..|. .|.  . ........|. .| 
gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefel

subfamily_STYX_pd Subfamily STYX 500-641 1.1e-25 83.6 In-house 14-162 (166) alignment
Range on Protein: 500-641
Range on HMM: 14-162/166.0
KIFDHIYLGSEW--NASDLDELEENGVGYILNITKECD-----NFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSAST
.|.  ..||       | |. |...|. .|. | .. .       ||.||.|  . . |.. |... .  |.  |. .. . | | ||| . ||||||. 
eilpglflgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaal

VIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILEASRQ
|||| |. ||.    |  .|. .|  | ||. |..||..|| |  |  .
viayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylaklt

PTEN_1 500-639 4.7e-24 80.3 In-house 43-194 (196) alignment
Range on Protein: 500-639
Range on HMM: 43-194/196.0
KIFDHIYLGSEWNA-SDLDELEENGVGYILNITKECDN---------FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKE--AGSKALVHCKMGIS
.|... |.||.  . .|||.|.|.|.  ..| . |...         || ....| ..   |.   .|  ..   . | . ...   | ..||||| |..
eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlg

RSASTVIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGILEAS
||.  |.|| |. ...| . ||..|. ||. ..|| .....|. |.  | |.
RsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 499-633 1.6e-23 76.7 In-house 4-149 (154) alignment
Range on Protein: 499-633
Range on HMM: 4-149/154.0
SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPER---------FKYCNIRLYDDVEEDLLNHWNTTYLFLSKAK--EAGSKALVHCKMGIS
||   ..|..|   | .  .|... .  |||.    .| |...         ..|.|..|.|||. |.... . .. |. .|      .| |||.. |.|
skeaiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvs

RSASTVIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
|||. .|.| |..  ..|  || ..|  | ||.||  |.|||...|
rsaallisylmdklkislslalellkdsryiikPnqGflkqleife

0045098 (Phosphotyrosine protein) phosphatases II 498-633 1.7e-23 78.9 In-house 22-268 (278) alignment
Range on Protein: 498-633
Range on HMM: 22-268/278.0
ASKIFDHIYLGSEW-----------------------------------------NASDLDELEENGVGYILNIT-------------------------
 |.|....|||. .                                          |.... | |.|. .|...|                         
pseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdf

---------------------------KECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKE--------------AGSKALVHCKMGISRSA
                           ... ... . ..| ..  ..  ....|...   . |. .| .               | . ||||..|..|..
tvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtG

STVIAYAMKEY---GMTLEYALDFVKGKRSI-IRPNDAFMKQLQVYE
  |.|| |.|.   |..|. |..... .| . . .|  ....|  ..
tlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefl

0037934 (Phosphotyrosine protein) phosphatases II 499-633 3e-23 78.1 In-house 40-238 (243) alignment
Range on Protein: 499-633
Range on HMM: 40-238/243.0
SKIFDHIYLGSE--------WNASDLDELEENGVGYILNITKEC---------------------------------------------DNFFPERFKYC
...........         . ||... | |.|...|...|...                                             |... . ..|.
iyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyh

NIRLYD----DVEEDLLNHWNTTYLFLSK-----AKEAGSKALVHCKMGISRSASTVIAYAMKEY-GMTLEYALDFVKGKRSI-IRPNDAFMKQLQVYE
 .   |    |  ||||.... .. |...     |   |.. ||||..|..|..  ..|| |... |..|| |..... .|.  . ..  ....|. ..
ylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeal

0040439 (Phosphotyrosine protein) phosphatases II 501-632 8.3e-23 76.7 In-house 32-241 (249) alignment
Range on Protein: 501-632
Range on HMM: 32-241/249.0
IFDHIYLGSEWNASDLDE------------------------LEENGVGYILNITKECDN----------------------------------------
|..  .|..  ||| .|                         | |.|...|...|... .                                        
ilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtlel

---FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKE------AGSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPN
    ..| ...  |. .|  . ..  . ...  |. ....       |.. ||||..|..|..  ..|| |     ||.|..|| |..... .|. . .|
tnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqn

DAFMKQLQVY
. ....|. .
peqyrflyea

0051082 (Phosphotyrosine protein) phosphatases II 498-632 9.2e-23 75.9 In-house 8-149 (151) alignment
Range on Protein: 498-632
Range on HMM: 8-149/151.0
ASKIFDHIYLGSEWNASDLDELEENGVGYILNITK-----ECDNFFPE-RFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEA-GSKALVHCKMGISRSA
.| . ...|...   | .|..|.|.|. .|.|...      | ...||  .....| . |. . .|  ....   ||... .  . . ||||..|..|..
fsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTG

STVIAYAMKeYGMTLEYALDFVKGKRS-IIRPNDAFMKQLQVY
  |..| |. .|..|| ||.... ||  ...||. |..||...
tlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal

0036282 (Phosphotyrosine protein) phosphatases II 499-636 9.3e-22 73.0 In-house 13-169 (174) alignment
Range on Protein: 499-636
Range on HMM: 13-169/174.0
SKIFDHIYLGSEWNAsDLDELEENGVGYILNITKEC---------------DNFFPERFKYCNIRLYDDVEEDLLNhWNTTYLFLSKAKEA--GSKALVH
| | .....|.   | ....| |.|. .... ..|.               . . .. ..|. .   |. . ||   . . . |. .| .   | . |||
syitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVH

CKMGISRSASTVIAYAMKEYGM-TLEYALDFVKGKR---SIIRPNDAFMKQLQVYEGIL
|..|..|..  |.|| |. ... .|. |||.|. .|   . . ... ....|. .| .|
CsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll

0045450 (Phosphotyrosine protein) phosphatases II 512-633 1.5e-20 69.6 In-house 88-300 (307) alignment
Range on Protein: 512-633
Range on HMM: 88-300/307.0
NASDL--------------------------------DELEENGVGYILNITKE-------CDNFFPER---------------------FKYCNIRLYD
|||                                    | |.||..|...|..       |. ..|.                      ... .... |
NAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtd

D-----------------VEEDLLNHWNTTYLFLSKAKE------AGSKALVHCKMGISRSASTVIAYAMKEYG--------MTLEYALDFVKGKRSIIR
                   . ..  .....  |. ....       |.. ||||..|..|... ..|| |....        ..|. |..... .|. . 
ldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgav

PNDAFMKQLQVYE
.|  ....|. ..
qnpeqyrflyeal

0042113 (Phosphotyrosine protein) phosphatases II 499-633 2.8e-19 65.0 In-house 48-239 (245) alignment
Range on Protein: 499-633
Range on HMM: 48-239/245.0
SKIFDHIYLGSEWNASDLD----ELEENGVGYILNITKEC----------------------------------------------DNFFPERFKYCNIR
..| .......   .....     | |.|. .|...|.|                                               |..  | . |. . 
yritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylp

LYDDVEEDLLNHWNTTYLFLSKAKE--AGSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
  |. . |||..    . |. || .  .. . ||||..|..|..  ..|| |     ||.|..|| |..... .|. ..... ....|. ..
wpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal

0040438 (Phosphotyrosine protein) phosphatases II 518-632 3.1e-19 64.9 In-house 105-271 (317) alignment
Range on Protein: 518-632
Range on HMM: 105-271/317.0
ELEENGVGYILNITKECDN---------------------------FFPERFKYCNIRLYDD----------------VEEDLLNHWNTTYLFLSKAKEA
 . |.||..|...|.....                           .  . ... .....|.                 . ..  ....   ||....||
mvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrea

----GSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVY
    |.. ||||..|..|... ..|| |     ||.|...| |..... .|. . .. .....|  .
ledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda

subfamily_STYXL1_pd Subfamily STYXL1 504-634 1.7e-17 57.1 In-house 18-151 (157) alignment
Range on Protein: 504-634
Range on HMM: 18-151/157.0
HIYLGSEWNASDLDELEENGVGYILNITKECDNFFPER---FKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKE
..||| . .| .    ..  |   .|.....|...       |  .|.. |. | |||.. .    |. | |. |.  ||  . ||||||. .||| | .
klylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmys

YGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEG
. .||. |....|  .. ..|| ||..||. .| 
kkitlkkaykylkkCkenvkPnrafveqlseWek

0038934 (Phosphotyrosine protein) phosphatases II 505-636 4.1e-17 57.9 In-house 38-176 (194) alignment
Range on Protein: 505-636
Range on HMM: 38-176/194.0
IYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEED--------LLNHWNTT-YLFLskAKEAGSKALVHCKMGISRSASTVIA
.|  | ..  .. .|   ..|.....|..   . ||.|.  .|. ..   .|        .|...    . ||  .. .| . .||||.|..|..  |.|
lyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefl..nedpggvvaVHCkaGlgRtGtlvaa

YAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGIL
| .. .||..| |..... ||  . ||  ....|... . |
YLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykel

0051429 (Phosphotyrosine protein) phosphatases II 504-632 4.8e-16 54.7 In-house 22-220 (272) alignment
Range on Protein: 504-632
Range on HMM: 22-220/272.0
H-IYLGSEW---NASDLDELEENGVGYILNITKECD------NFFPERFKYCNIRLYDDVEEDLLNHW--------------------------------
. .|... .   .| |.. |.|.|. .|.....|.        .... ..|... ..||.... | ..                                
grlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsageare

----------------NTTYLFLSKAKEaGSKALVHCKMGISRSASTVIAYAMKeYGMT--------------LEYALDFVKGKRSIIRPNDAFMKQLQV
                ..   .|.   . | . ||||. |..|..  | .. .  .|..              || |.. .. .|  ..........|. 
vmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflye

Y
.
a

0039614 (Phosphotyrosine protein) phosphatases II 518-633 6.9e-16 54.0 In-house 120-285 (297) alignment
Range on Protein: 518-633
Range on HMM: 120-285/297.0
ELEENGVGYILNITKECDN------FFPERFKYCNIR---LY---------------------------------DDVEEDLLNHWNTTYLFLSKAKE--
 . |.|| .|...||....      ..||.  ...     |                                  |.   ..|..    . .. .| .  
mvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael

-AGSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
  | . ||||..|..|... ..|| |     ||.|.... |..... .|. ..... ....|. ..
pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydal

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 505-630 9.4e-16 51.2 In-house 6-135 (145) alignment
Range on Protein: 505-630
Range on HMM: 6-135/145.0
IYLGSEWNASDLDELEENGVGYILNITKE----CDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKE
.| ||  .|.|.  |.| |.  |.|..      ...   | ..   |   |    || .|..    |. | || |.  .|||  |.||| .  .|. || 
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

YGMTLEYALDFVKGKRSIIRPNDAFMKQLQ
 .|||  |   |. .|    ||  |.|.| 
cnmtlseaarqvrsnrllaypnvtflknll

0036941 (Phosphotyrosine protein) phosphatases II 502-633 1.1e-15 53.2 In-house 23-273 (297) alignment
Range on Protein: 502-633
Range on HMM: 23-273/297.0
FDHIYLGSE----------------------------------WNASDLDELE------------------------ENGVGYILNITKE-------CDN
.....|||                                    ||| .|  .                        |..|  |...|..       |. 
lpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq

FFPER---------------------FKYCNIRL---Y----------------DDVEEDLLNHWNTTYLFLSKAKE------AGSKALVHCKMGISRSA
..|.                      .... .|    .                .  . .. .....   |. ....       |.. ||||..|..||.
ywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsg

STVIAYAM--------KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE
. ..|. |        ||.|...  |. ... .|  . ..  ....|  ..
tfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeal

subfamily_PTPMT1_pd Subfamily PTPMT1 538-634 1.9e-14 48.5 In-house 70-166 (171) alignment
Range on Protein: 538-634
Range on HMM: 70-166/171.0
FPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEG
  .  .. ...  |  |.  |.. . .  |..| .. |..  |||| | .|||. |..| ||.. ...| ||...| ||.||| ... .|.|| || 
kklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyee

subfamily_MSG5_pd Subfamily MSG5 526-638 2.1e-14 47.0 In-house 50-162 (165) alignment
Range on Protein: 526-638
Range on HMM: 50-162/165.0
YILNITKECDNF---FPErFKYCNIRLYDDVEedLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKRSIIRPN
 ..|..|| ...    |   ||  |.   | .  .    ..    .  |.  . | ||||. |.||||| ..|| || |...|. | | .|..   | |.
lvinvakeindlellvpa.vkyyhiewehdsk..ivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddisps

DAFMKQLQVYEGILEA
  .. ||  .| .|..
iglifqlmewevalsk

0043336 (Phosphotyrosine protein) phosphatases II 519-632 2.2e-14 49.1 In-house 108-272 (278) alignment
Range on Protein: 519-632
Range on HMM: 108-272/278.0
LEENGVGYILNIT-----------------------------------------------KECDNFFPERFKYCNIRlYDDVEEDLLNHWNTTYLFLSKA
. |.||  |...|                                               ..   ..  .. | ..   ..| |.|  ...    .... 
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp.dhgvpeslsllldflkavreal

KEAGSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVY
.  ... ||||. |..|..  ...| .     ||.|..|| |..... .|  . ... ....|  .
edsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyea

DEK_C DEK C terminal domain 447-489 1.1e-12 37.2 Pfam-A 8-50 (54) alignment
Range on Protein: 447-489
Range on HMM: 8-50/54.0
KLKEIMIQCDLETVTSKMVRISLEKEIGKELKEYKRFIDKQIL
...||. . ||||||.| ||  ||...| .|.|.| ||...| 
evreiLkeaDLetvTkkqvrkeLearlgvdLserKafIkdlie

0047943 (Phosphotyrosine protein) phosphatases II 519-629 9.9e-10 33.8 In-house 97-264 (273) alignment
Range on Protein: 519-629
Range on HMM: 97-264/273.0
LEENGVGYILNITKECDN-------FFPERFK--------------------------------------------YCNIRlyddvEEDLLNHWNTTYLF
. |..| .|  .|.. ..       ..|.                                               | ..      . .   ...    |
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwp.....dhgvppslesllef

LSKAKE------AGSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPNDAFMKQL
. ....       ... .|||. |..|... .... .     ||.|.... |. ... .|  . ..  ....|
ielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl

0051299 (Phosphotyrosine protein) phosphatases II 521-623 1.9e-08 29.6 In-house 114-272 (288) alignment
Range on Protein: 521-623
Range on HMM: 114-272/288.0
ENGVGYILNITKE-------CDNFFP--------------------ERFKYCNIRL------------------------YDDVEEDLLNHWNTTYLFLS
|..| .|  .||.       |. ..|                    . ... ....                         ..| ...   ..   |. .
eqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrk

KAKEAGSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIRPND
. .  |.  .|||. |..|..  .... .     ||.|.... |. ... .|  . .. 
alasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtp

0050432 (Phosphotyrosine protein) phosphatases II 521-620 9.8e-08 27.1 In-house 130-282 (308) alignment
Range on Protein: 521-620
Range on HMM: 130-282/308.0
ENGVGYILNITKE-------CDNFFPERFK----YCNIRLYDDV-----------------------------------EEDLLNHWNTTYLFLSKAKEA
|..| .|  .||.       |. ..|.  .    ...      .                                   . .  ....    || .... 
eqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrks

--GSKALVHCKMGISRSASTVIAYAM-----KEYGMTLEYALDFVKGKRSIIR
  |.. .|||. |..|..  .... .     ||.|.... |. ... .|    
lpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmv

subfamily_CDC14_pd Subfamily CDC14 567-630 1.2e-06 22.7 In-house 255-320 (328) alignment
Range on Protein: 567-630
Range on HMM: 255-320/328.0
FLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKR--SIIRPNDAFMKQLQ
||. |..|  .. |||| |. |  . . .| ||.|..| . |. ...  |  |.| | . |... |
fleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGsvigpqqkfleekq

0046845 (Phosphotyrosine protein) phosphatases II 556-617 3e-06 22.3 In-house 186-254 (284) alignment
Range on Protein: 556-617
Range on HMM: 186-254/284.0
DLLNHWNTTYLFLSKaKEAGSKALVHCKMGISRSASTVIAYAMKEY--------GMTLEYALDFVKGKRS
|||. ...   .|..  . |.. .|||. |..|..  .... ..|.        |.... |. ... .| 
dlleflrlvrellen.lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRp