subfamily_Auxilin_pd |
Subfamily Auxilin |
275-439 |
1.9e-87 |
284.1 |
In-house |
1-165 (166) |
alignment |
Range on Protein: 275-439
Range on HMM: 1-165/166.0
VASYTKSELDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNLSQRTYRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRD
||||.|..|||||||||||||||||||.|||||| |||||||||.||...|.|.||||||||.||...||...|.||.| ||| |..||||.| |...|
vasyakndlDisyitsriivmsfPaegvestyknniddvrsfLesrhpekylvynlsqrtyrtaklssrvveagwparraPnLeslvevcrnlyswlkkd
PKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKRGPPGITQSQKRYMEYISGMLS
||||.|.||.||.|.||..||..|.||||.|... ....||||| |.|...|.|||.||....|.
pknvvvvhckDGraasavlvsallvfcrllsepesavrlfsvkrlpiglspsekryleyladlla
|
subfamily_PTEN_pd |
Subfamily PTEN |
279-438 |
3.2e-44 |
146.1 |
In-house |
16-179 (184) |
alignment |
Range on Protein: 279-438
Range on HMM: 16-179/184.0
TKSELDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNL-SQRTYRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRDPKN
. .||.||||..||.|..|||.||..|.| ..|| |||..|..||...|| |.|.| .||..||. ..| . ||.| || ...... |...|.||
dgldLDlsyiteniiamgyPaeklealyRnsledvvkflekkhkdhykiynlrserkydskkfdgrvavypfdDhnppplelleeivediekwleedkkn
VCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKRGP--PGITQ-SQKRYMEYISGML
| |.||. || . ......| ..|... . .| .|. .| |.| ||.||.|| . .|
vvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaRtknkkgvtiPsqrRYveYyekll
|
subfamily_Tensin_pd |
Subfamily Tensin |
280-441 |
8.5e-44 |
142.3 |
In-house |
8-174 (189) |
alignment |
Range on Protein: 280-441
Range on HMM: 8-174/189.0
KSELDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNLSQRTYRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRDPKNVC
| .||..|||.|||..||||||||..|.. . || .|...|. .| |||||.. | |....| | |.| . | | | .|... |.. ||.||
kvdldltyiteriialsfpaegleekyrenlkdvakllkskhndkylvfnlsekrydisklnkkvldfGWPdllaPsleklcsicksldsWlkadpqnvv
VIHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKR-----GPPGITQSQKRYMEYISGMLSPT
|.|| || . .||... . .. .. | .| |..|| . . ||.||.||.||.||
vvhckGgkgrigvvvsaymkyskisasadaaldrfamkrflddklsgetqPsqrryveyfsglLsgk
|
subfamily_VSP_pd |
Subfamily VSP |
271-451 |
4.8e-37 |
121.9 |
In-house |
20-211 (212) |
alignment |
Range on Protein: 271-451
Range on HMM: 20-211/212.0
VAQTVASYTKS--ELDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNL-SQRTYRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNM
|.. ||. .||..|.| ||| ||||. | .| |.| |..| ||.|.|. ||.|.|| |.|.| .. |.|||. . . |.| | ......
vsenkrrytqdGfdldltyvteriiamsfpssGkqslyrnpisevarfldtkhrdhykvvnlcseraydekyfnnrvkriliddhnvpkleellvftkev
YLWMQRDPKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKRGPPGI--------TQSQKRYMEYISGMLSPTASIMPHQRVL
|...|.||| .||| || . ||| ..| .|.| . ||. |...| . | |||||..|. . .| ...|
kewlekdlknvlaihckGGkgrtGtivcalllaseifetakesldyfgerrtdktegekfqGvqtpsqkryvgyleqvktkynrklppaktl
|
PTEN_1 |
|
270-439 |
1.1e-34 |
115.0 |
In-house |
7-193 (196) |
alignment |
Range on Protein: 270-439
Range on HMM: 7-193/196.0
RVAQTVASYTKSELDISYITSRIIVMS-FPAEG-----LESTYKNGIDDVRSFLETRHSGH-YHVFNLSQR------TYRPAK-FENRVS--DCGFPAKR
|. .. .... ||..|||||||.|. .|... |..|.. ..||...|..... . ..|.||| . .|.. . |...|. .....
rsskknlalptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhg
PPNLVLLYHVCRNMYLWMQRDP-KNVCVIHCMDGKASSATIVSSFLTFCRLfSTVDVSLYMFSVKRGPPG-ITQSQKRYMEYISGMLS
.|.| | ..|... |...|| .||...|| |. |.|.| ..| ... .|.| | .. || | . . ||.|..|| . .|.
apslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk.ltadeAlelvrekRppgapnspsqerlleyfaella
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
282-438 |
7.1e-26 |
86.4 |
In-house |
9-169 (174) |
alignment |
Range on Protein: 282-438
Range on HMM: 9-169/174.0
ELDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNLSQ-RTYRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRDPKNVCV
||.||||.|.|....|.. .| ...|| .| ..|| .. |.| ..|. . . . .. .. ....| .|.| |..... .. ....||.....
pldlsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvl
IHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKR---GPPGITQSQKRYMEYISGML
.||. |. ..|.| .| ..|..... |... .| .. .|.|| |. |.. .|
VHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll
|
0038934 |
(Phosphotyrosine protein) phosphatases II |
286-432 |
4.9e-23 |
77.2 |
In-house |
14-170 (194) |
alignment |
Range on Protein: 286-432
Range on HMM: 14-170/194.0
SYITSRIIVMSFPAEG-----LESTYKNGIDDVRSFLETRHSGHYHVFNLS--QRTYRPAKFEN---RVSDCGFPAK-RPPNLVLLYHVCRNMYLWMQRD
..|| |.|....|..| .|..|.....|. ..|.... ....| .|. |.| | .||. .. .. || . .|.| .|.. .. .. ....|
diitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflned
PKNVCVIHCMDGKASSATIVSSFLTFCRLFsTVDVSLYMFSVKRGPPGITQSQKRYME
|..|...||. |. ..|.| ..| .. . ... ....|. ||.. ..|.. ...
pggvvaVHCkaGlgRtGtlvaaYLiyrlgm.saeeAialfrekRpgaipnqdyleall
|
Pkinase |
Protein kinase domain |
61-197 |
4.7e-22 |
68.3 |
Pfam-A |
124-255 (260) |
alignment |
Range on Protein: 61-197
Range on HMM: 124-255/260.0
LKLENFLIGSKKTLKLCDFGSATSKsyqpdsswsslkRSTLEDEFARHTTPMYRPPEILDlyENFPINHAMDVWALGCMLYTMCYRQHPFEDS---AKLR
|| ||.|. .|..||..|||.| .. |. . |. |..||.| .. . ...|||.||..||... .. ||... .|.
LKpeNiLldekgelkiaDFGlakkl............eksseklttlvgtreYmAPEvll..kakeytkkvDvWslGvilyelltgklpfsgeseedqle
IINANYTIPEDDE------EYMILHDLIRAMLQVDPRNRPPLEVIV
.|... . . . . . | |||. .|. ||..|. .| |.
lirkilkkkleedepkssskseelkdlikkllekdpakRltaeeil
|
PTEN_C2 |
C2 domain of PTEN tumour-suppressor protein |
447-584 |
1.5e-18 |
58.3 |
Pfam-A |
2-127 (134) |
alignment |
Range on Protein: 447-584
Range on HMM: 2-127/134.0
HQRVLLIKSLRLTPVPLYnKMRSGCpsvRPYVRTSVPDELIRFGGHEVKGQRGFEVEDASAFIDLNIPVCGDVMVVVYHARSTfggkvqgK----Vtglk
... | .||..| ..| . |.|.|| .|.|. . .. . .. | .. . ... .. ..||.|||.| ..| .|. .
npkrlelksiilegiPnf.ktrggc...kpkvkvyngkkkvfkelasykdsterraktfivkepnrlpveGDvlveflhkdsk.......lpkkek....
MFQFQFNTGFIEPGTKEISFNRYELDFFELDKfAEHFHASLD
.|...||| ||| .. . ....||| . || ..|.
ifrvwFNTsFieknqnvltlpkneLDkalkdk.dkkfsknfk
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
283-434 |
1.6e-15 |
52.6 |
In-house |
17-166 (182) |
alignment |
Range on Protein: 283-434
Range on HMM: 17-166/182.0
LDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETRHSGHY-HVFNLSQRTYRPAKFEN---RVSDCGFPAKRPPNLVLLYHVCRNMYLwmqrdPKNV
.|..||. .....|.|| . |. . ...| .||.. .. .. .. ||. . | | ..|. .. . ..| .|.| |.. .. .. ....
rdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpdldelldfieevle.....eggp
CVIHCMDGKASSATIVSSFLTFCRlFSTVDVSLYMFSVKRGPPGITQSQKRYMEYI
...||. |. ..|.| .| .. ... . .. .| || .| .. ..
vlVHCsaGvgRtgtlvaaylmkkl.gvsleeavklvrsrRpgmvitpnqyfflqla
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
280-433 |
1.1e-14 |
50.1 |
In-house |
7-167 (176) |
alignment |
Range on Protein: 280-433
Range on HMM: 7-167/176.0
KSELDISYITSRIIVMSFPAEGLESTYKNGIDDVRSFLETrhsGHYHVFNLSQRT-----------YRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNMY
.||..||. ..|..|.|. . ...... |... ..| |...|.|| ... . |.. .. ...| .|.| ||..... ..
gldldldyinanlilgsrpiatqgplprtladflemlkel...gitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefir
LWMQRDpkNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKRG-PPGITQSQKRYMEY
. ... .. ..||. |. ..|.| .| .. . .|. |... .| |..| |. ..
ealkeg..gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflye
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
279-413 |
2e-14 |
49.2 |
In-house |
79-263 (297) |
alignment |
Range on Protein: 279-413
Range on HMM: 79-263/297.0
TKSELDISYI-----------TSRIIVMSFPAEG-----LESTYKNGIDDVR----------------------------SFLETRHSGHYHVFNLSQRT
.. || .|| | ..|....| .. .. ...|. . .|.. | ..|.|..|. .
dgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtn
YRPAKFENRVSDCGFPAKRPP-NLVLLYHVCRNMYLWMQRD-PKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSL----YM
. . .. ... |.| .| .| ||..... . ..... .......||..|. ..|.. .| ...| .. .|.. .
ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavke
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
282-438 |
2.2e-14 |
49.0 |
In-house |
12-160 (172) |
alignment |
Range on Protein: 282-438
Range on HMM: 12-160/172.0
ELDISYITSRIIVMSFPaeglestYKNGIDDVRSFLETRHSGHyhVFNLSQRTYRPAKFEN---RVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRDPKNV
||..||. |.|.. .| . | ..|.. .| ... .| ..|| ...| | ..| .. ...| .|.| ||..... .. .....|...
yldlyyipdrfiatqgp.......lrntladfwrmlkelgith..ivnltellydpellerlgiqylylpwpDhgvpllellleflefidellalspggp
CVIHCMDGKASSATIVSSFLTFCRLfsTVDVSLYMFSVKRGPPGITQSQKRYMEYISGML
...||. |. ..|.| .| ..| ... . .. ||. ..|| |. | . .|
vlVHCsaGvgRtgtlvaaylmllgl..sleeavalvrekRpgavqnpsqyrflyyfekll
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
283-430 |
6.1e-14 |
47.4 |
In-house |
6-143 (151) |
alignment |
Range on Protein: 283-430
Range on HMM: 6-143/151.0
LDISYITSRIIVMSFPAEglestykngidDVRSFLetRHSGHYHVFNLSQRT---YRPAKFEN---RVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRDPK
...||.|........| . |. .| .. |.....|| . . | | ... .| .. .. .|.| |... .... .......
infsyvtgglyrsggpla...........dflell..kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkn
NVCVIHCMDGKASSATIVSSFLTFCRlfSTVDVSLYMFSVKRGpPGITQSQKRY
.....||. || ..|.| .| .. ... | .. ||. .. .| ..
gpvlvHCsaGkgRTGtlvalylmllg..vsleealeeyrlkrp.gvvqpnqqfl
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
279-428 |
2.3e-12 |
42.3 |
In-house |
31-232 (245) |
alignment |
Range on Protein: 279-428
Range on HMM: 31-232/245.0
TKSELDISYI----------TSRIIVMSFPAEGLES-----TYKNGIDDVR------------------------------SFLETRHSGHYHVFNLSQR
....|| .|| | ..|....|... ...|| . .|.. | ..|.|..|.
dggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevt
--TYRPAKFENRVSDCGFPAKRPPN-LVLLYHVCRNMYLWMQRDPKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVS----LYMFSVKRGPPGITQS
. . .. ... ..| .|. | || ... . ....|.......||..|. ..|.. .| ...| .. .|| .... .|. |.|
nlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtps
QK
|
qy
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
283-432 |
2.6e-12 |
42.3 |
In-house |
37-235 (243) |
alignment |
Range on Protein: 283-432
Range on HMM: 37-235/243.0
LDISYITSRIIVMSFPAEGLEST---------YKNGIDDVR----------------------------SFLETRHSGHYHVFNLSQRT---YRPAKFEN
.. .|.| |.|....| .. ...||. . .|...| ..|.|..|. . . . ..
anliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvi
RVSDCGFPAKRPPN--------LVLLYHVCRNMYLWMQRDPKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLYMFSVKRGP-PGITQSQKRYME
.. ..| .|. | .. ...........|.......||. |. ..|.. .| .| ... . .. .|. |.|| |.
hyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrfly
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
277-413 |
5.2e-12 |
41.3 |
In-house |
65-251 (278) |
alignment |
Range on Protein: 277-413
Range on HMM: 65-251/278.0
SYTKSELDISYI----------TSRIIVMSFPAEGLESTYKNGIDDVR----------------------------------SFLETRHSGHYHVFNLSQ
| ....|| .|| . ..|....| .. . . . . . . .|.. | ..|.|..|
sllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlev
R--TYRPAKFENRVSDCGFPAKRPP-NLVLLYHVCRNMYLWMQrDPKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLY----M
. . .. ... |.| | .| || . .. . ... |.... ..||..|. ..|.. .| ...| .. |.|. .
tnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavke
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
287-426 |
1.3e-11 |
40.2 |
In-house |
143-291 (307) |
alignment |
Range on Protein: 287-426
Range on HMM: 143-291/307.0
YITSRIIVMSFPAEGLESTYKNgidDVRSFLETRHSGHYHVFNLSQRTYRPAKFENRVSDCGF---PAKRPP-NLVLLYHVCRNMYLWMQRD-PKNVCVI
. ....... .| || | ||.| .. .|.. | ..|.|..| ... ... .| . | | .. | . .. . ..... .......
elgrekcaqywPdegeeltygn...ftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlV
HCMDGKASSATIVSSFLTFCRL--------FSTVDVSLYMFSVKrgpPGI--TQS
||..|. ..|.. .| ..| .. .. .. . . ||. ...
HCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR...pgavqnpe
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
293-437 |
1.9e-11 |
39.3 |
In-house |
5-148 (152) |
alignment |
Range on Protein: 293-437
Range on HMM: 5-148/152.0
IVMSFPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNLSQRT-YRPAKFENRVSDCGFPAKRPPNLVLLYHVCRNMYLWMQRDPKNVCVIHCMDGKASSA
. |.|.. . . .. | ..|. .| . . ... . . . . .. .. . .| .|.| | . . ....|.......||. |. ..
yampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtg
TIVSSFLTFcrLFSTVDVSLYMFSVKRGPPGITQSQKRYMEYISGM
|.| .| | ... . .. || ....| |. . ...
tlvaaylml..lgvsleeavalvrekRpgavpnpgqlrflyefekl
|
Pkinase_Tyr |
Protein tyrosine kinase |
33-200 |
3.5e-11 |
32.6 |
Pfam-A |
105-259 (259) |
alignment |
Range on Protein: 33-200
Range on HMM: 105-259/259.0
KLKVRRVIAEGFAfvYVAQENSTGKEFALKleNFLIGSKKTLKLCDFGSATSKsyqpdsswssLKRSTLEDEFARHTTPMYRPPEILDLYEnfpINHAMD
.|.. ||.| . | .... .. | . | |. ..|. |..||| | . |... ... ... . .||.|. . .... |
llsfalqiAkGme..yLeskklvHrdLaar..NvLleenkvvkisDfGLardi..........ekddyykkkekaklpvkWmapEslkekk...ftsksD
VWALGCMLYTMCY-RQHPFEDSAKLR---IINANYTIPEDDEEYMILHDLIRAMLQVDPRNRPPLEVIVAQL
||. | .|. .. ..|... . . ..... ... .. |..|.. .. .|..|| .. .| .|
vWsfGvllwEiftlgespypglsneevleklkegkrlekpencpeelyelmkqCweeepekRptfkelvekl
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
297-434 |
3.9e-11 |
38.3 |
In-house |
3-138 (145) |
alignment |
Range on Protein: 297-434
Range on HMM: 3-138/145.0
FPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNLSQRTYRPAKFENRVSDCGFPAKRPPNL-VLLYHVCRNMYLWMQRDpkNVCVIHCMDGKASSATIVS
.|.| |.. | ... ..... . .. |...|.||. .. . .. .. ...| .|.| ||..... . ..... .....||. |. ..|.|
wpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlva
SFLTFCRLFSTVDVsLYMFSVKRGPPGITQSQKRYMEYI
.| ... .| .. | .. .| ....| |....
aylmlllgvsleea.lelvrsqrpgavpnpgqlrflyef
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
297-434 |
5.2e-11 |
38.0 |
In-house |
3-140 (144) |
alignment |
Range on Protein: 297-434
Range on HMM: 3-140/144.0
FPAEGLESTYKNGIDDVRSFLETRHSGHYHVFNLSQRTYRPAKFEN--RVSDCGFPAKRPPNL-VLLYHVCRNMYLWMQRDpkNVCVIHCMDGKASSATI
.|.| |.. | ... ..... . .. |...|.||. . . . .. ...| .|.| ||..... . ..... .....||. |. ..|.
npseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg..gpvlVHCsaGvgRtgtl
VSSFLTFCRLFStVDVSLYMFSVKRGPPGITQSQKRYMEYI
| .| ... .| .. |... .| ....| |....
vaaylmkklgls.leealalvrsrrpgavpnpgqlrfLley
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
283-435 |
2.5e-10 |
35.8 |
In-house |
21-167 (178) |
alignment |
Range on Protein: 283-435
Range on HMM: 21-167/178.0
LDISYITSRIIVMSFPAeglestykngiDDVRSFLetRHSGHYHVFNLSQ---------RTYRPAKFENRVSDCGFPAKRPPN-LVLLYHVCRNMYLWMQ
...|.|. .....|.|. | . .| . | |. ||.. | | ... .. ...| .|. | .. ... . ...
inaseilpglylgslpp...........addlell..kelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeald
RDPkNVCVIHCMDGKASSATIVSSFLTFCRLFsTVDVSLYMFSVKRGpPGITQSQKRYMEYIS
... .....||. |. |.|.| .| .. . ... . .. .| ....| |.....
ekg.gpvlVHCsaGvgRsgtlvaaylmkklgl.sleeaielvrerRp.ivpnpgqlrqLyefe
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
282-412 |
9.9e-10 |
33.9 |
In-house |
46-215 (249) |
alignment |
Range on Protein: 282-412
Range on HMM: 46-215/249.0
ELDISYITSRIIVMSFPAEGLESTYKNGIDDVR-----------------------------------SFLETRHSGHYHVFNLSQRT-YRPAKFENRVS
.| .||. |.|....| .. . . . . . . .|.. ....|.|..| | . ... ..
yidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhi
DC-GFPAKRPP-NLVLLYHVCRNMYLWMQRD-PKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSLY
. ..| | .. | .. . ..... .......||..|. ..|.. .| ...| . .|.|.
qytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdle
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
282-432 |
1.7e-09 |
33.0 |
In-house |
6-265 (278) |
alignment |
Range on Protein: 282-432
Range on HMM: 6-265/278.0
ELDISYITSRIIVMSFPAEGLESTYKNGID----------------------------------------------------------------------
.||..... .......| | ... | ...|
sldlllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrek
---------------------DVRSFlETRHSGHYHVFNLSQRTYRPAKFENRVSDC-GFPAKRPPNLV---LLYHVCRNMYLWMQ------------RD
.. . .. . ...| ||. . . ... .. .. ..| .|.| . .... . ... |
caqywpeggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllld
PKNVCVIHCMDGKASSATIVSSFLTFCR---LFSTVDVSLYMFSVKRGPPGITQSQKRYME
.......||. |. ..|.| .| .. .. .. .. | ..| ...| |...
sggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrfly
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
280-414 |
2.2e-09 |
32.5 |
In-house |
66-251 (317) |
alignment |
Range on Protein: 280-414
Range on HMM: 66-251/317.0
KSELDISYI----------TSRIIVMSFPAEG-----LESTYKNGIDDVRSFLETR------------------------------HSGHYHVFNLSQRT
.. || .|| . ..|....| .. .. ...|. . .. |. . .......|
ggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtleved
-YRPAKFENRVSDCGF-PAKRPP-NLVLLYHVCRNMYLWMQrDPKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSL----YMF
. . ...... . . | .| .. || . .. . ... ||......||..|. ..|.. .| ...| . .|.. ...
lgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkel
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
276-426 |
2.6e-09 |
32.3 |
In-house |
62-259 (284) |
alignment |
Range on Protein: 276-426
Range on HMM: 62-259/284.0
ASYTKSE-LDISYITSRIIVMSFPAEG-----------------------------LESTYKNGIDDVRSF-------LETRHSGHYHVFNLSQRTYRPA
||| . ||..||. ..|....| .. . | . ...| . |.. . ..| |..|. . . .
AsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgyt
KFENRVSDCGF----PAKRPPNLVLLYHVCRNMYLWMQR-DPKNVCVIHCMDGKASSATIVSSFLTFCRLFS-----TVDVSLYMFSVKRGPPGITQS
... .| . . ||.. | . .| . .... ..... |.||..|. ..|.. | ...| .||| .. ... || |.
gesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqt
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
287-433 |
3.1e-08 |
29.2 |
In-house |
118-272 (314) |
alignment |
Range on Protein: 287-433
Range on HMM: 118-272/314.0
YITSRIIVM---------------------SFPAEGLEstyknGIDDVRSFLETRhsghyhvfnlsQRTYRPAKFENRVSDC---GFPAKRPPNLVLLYH
. .|.||| .. |. .. ... . . . ...| | .||... .| .| | ...
dlnvrdivmsrdevladelsrLdaAlgKtpllildgng.....neptaadlellk...........eelydpelferlgikylripvpDgsaplledfde
VCRNMYLWmqrDPKNVCVIHCMDGKASSAT-IVSSFLTFCRLFsTVDVSLYMFSVKRGpP----GITQSQKRYMEY
... . . |.... ..||..|| ..| .| .| .. . ... | .. || | .....| ..
flefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRp.inpnpgfieqleqyefi
|
DnaJ |
DnaJ domain |
1237-1280 |
7.1e-08 |
21.4 |
Pfam-A |
13-54 (64) |
alignment |
Range on Protein: 1237-1280
Range on HMM: 13-54/64.0
EHNQVKKWYRKAVLSAHPDKQVGTPneELAKLIFMELSDAWSAF
...|| ||| .| |||| . . | |. | |...|...
sdeeIkkaYrklalkyHPDknkdde..eeaeekfkeineAyevL
|
Kinase-like |
Kinase-like |
110-190 |
1.5e-06 |
16.5 |
Pfam-A |
206-289 (289) |
alignment |
Range on Protein: 110-190
Range on HMM: 206-289/289.0
TPMYRPPEILDLY-----ENFPINHAMDVWALGCMLYTMCYRQHPFEDSAKLRIINANYTIPEDDEEYmiLHDLIRAMLQVDPRNR
. |||.| ... ..|..|.|.|| .| . .. ||. .|. ... .. . | .. |.. .|| . ..|
ekalaPpellaekggytsnttkmthkldaWqlGlviysiwclrlPftllaeeaseewkfklckkvpek..vklLvkklLqrsqeaR
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
316-426 |
2.3e-06 |
22.7 |
In-house |
153-271 (288) |
alignment |
Range on Protein: 316-426
Range on HMM: 153-271/288.0
FLETRHSGHYHVFNLSQRTYR---PAKFENRVSDCGF----PAKRPPNLVLLYHVCRNMYLWMQrDPKNVCVIHCMDGKASSATIVSSFLTFCRL--FST
.|.. . ..| |..| . .. . ... .| . |... || . .| .. ... ......|.||..|. ..|.. .| ...| .
llseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekegg
VDVSLYMFSVKRGPPGITQS
||| .. ... ||. |.
vdvleavkrlreqRpgmvqt
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
316-412 |
3.1e-06 |
22.3 |
In-house |
141-241 (273) |
alignment |
Range on Protein: 316-412
Range on HMM: 141-241/273.0
FLETRHSGHYHVFNLSQRT--YRPAKFENRVSDCGFPAKRPP-NLVLLYHVCRNMYLWMQRD-PKNVCVIHCMDGKASSATIVSSFLTFCRLFSTVDVSL
.|.. . ..| |..| . . .. . . |.| | .| | . .. . ... . ... |.||..|. ..|.. .| ...| . |..
llseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdv
Y
.
l
|