Gene Auxilin-2 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTEN
Subfamily Auxilin
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP043_AA protein Get Run
SpurP043_AA_269-439 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Auxilin_pd Subfamily Auxilin 275-439 1.9e-87 284.1 In-house 1-165 (166) alignment
subfamily_PTEN_pd Subfamily PTEN 279-438 3.2e-44 146.1 In-house 16-179 (184) alignment
subfamily_Tensin_pd Subfamily Tensin 280-441 8.5e-44 142.3 In-house 8-174 (189) alignment
subfamily_VSP_pd Subfamily VSP 271-451 4.8e-37 121.9 In-house 20-211 (212) alignment
PTEN_1 270-439 1.1e-34 115.0 In-house 7-193 (196) alignment
0036282 (Phosphotyrosine protein) phosphatases II 282-438 7.1e-26 86.4 In-house 9-169 (174) alignment
0038934 (Phosphotyrosine protein) phosphatases II 286-432 4.9e-23 77.2 In-house 14-170 (194) alignment
Pkinase Protein kinase domain 61-197 4.7e-22 68.3 Pfam-A 124-255 (260) alignment
PTEN_C2 C2 domain of PTEN tumour-suppressor protein 447-584 1.5e-18 58.3 Pfam-A 2-127 (134) alignment
0041856 (Phosphotyrosine protein) phosphatases II 283-434 1.6e-15 52.6 In-house 17-166 (182) alignment
0046846 (Phosphotyrosine protein) phosphatases II 280-433 1.1e-14 50.1 In-house 7-167 (176) alignment
0039614 (Phosphotyrosine protein) phosphatases II 279-413 2e-14 49.2 In-house 79-263 (297) alignment
0043147 (Phosphotyrosine protein) phosphatases II 282-438 2.2e-14 49.0 In-house 12-160 (172) alignment
0051082 (Phosphotyrosine protein) phosphatases II 283-430 6.1e-14 47.4 In-house 6-143 (151) alignment
0042113 (Phosphotyrosine protein) phosphatases II 279-428 2.3e-12 42.3 In-house 31-232 (245) alignment
0037934 (Phosphotyrosine protein) phosphatases II 283-432 2.6e-12 42.3 In-house 37-235 (243) alignment
0043336 (Phosphotyrosine protein) phosphatases II 277-413 5.2e-12 41.3 In-house 65-251 (278) alignment
0045450 (Phosphotyrosine protein) phosphatases II 287-426 1.3e-11 40.2 In-house 143-291 (307) alignment
0049260 (Phosphotyrosine protein) phosphatases II 293-437 1.9e-11 39.3 In-house 5-148 (152) alignment
Pkinase_Tyr Protein tyrosine kinase 33-200 3.5e-11 32.6 Pfam-A 105-259 (259) alignment
0048076 (Phosphotyrosine protein) phosphatases II 297-434 3.9e-11 38.3 In-house 3-138 (145) alignment
0048179 (Phosphotyrosine protein) phosphatases II 297-434 5.2e-11 38.0 In-house 3-140 (144) alignment
0044763 (Phosphotyrosine protein) phosphatases II 283-435 2.5e-10 35.8 In-house 21-167 (178) alignment
0040439 (Phosphotyrosine protein) phosphatases II 282-412 9.9e-10 33.9 In-house 46-215 (249) alignment
0045098 (Phosphotyrosine protein) phosphatases II 282-432 1.7e-09 33.0 In-house 6-265 (278) alignment
0040438 (Phosphotyrosine protein) phosphatases II 280-414 2.2e-09 32.5 In-house 66-251 (317) alignment
0046845 (Phosphotyrosine protein) phosphatases II 276-426 2.6e-09 32.3 In-house 62-259 (284) alignment
0049772 (Phosphotyrosine protein) phosphatases II 287-433 3.1e-08 29.2 In-house 118-272 (314) alignment
DnaJ DnaJ domain 1237-1280 7.1e-08 21.4 Pfam-A 13-54 (64) alignment
Kinase-like Kinase-like 110-190 1.5e-06 16.5 Pfam-A 206-289 (289) alignment
0051299 (Phosphotyrosine protein) phosphatases II 316-426 2.3e-06 22.7 In-house 153-271 (288) alignment
0047943 (Phosphotyrosine protein) phosphatases II 316-412 3.1e-06 22.3 In-house 141-241 (273) alignment