Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPN12_pd | Subfamily PTPN12 | 23-308 | 1.7e-141 | 465.3 | In-house | 3-289 (290) | alignment | ||
Range on Protein: 23-308
Range on HMM: 3-289/290.0
SLDGSDSFELEFNHLKQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRM
. .|...|. ||..||..|..|..||||.|.|||...|..|||||||||.|.||. ||.|...|||||.||||.||......|.|||||||.|...||||
ekegeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrm
LWECNTEIIVMACNEFELGRHKCERYWVDEGEEHC-FGDILVTQIGQQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREY
.||.|.||.||||.|.|||..||||||..||||.. ||.. ||.. ...|..||.|||||....||.....|||||||||||||.|.|..|..|.||||.
iweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrel
QTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHLGIKPEDYG
|..|. |.|||||||.||||||..|||||..|. |||.......|.....||||.|.|||..|||||..||....|..|.|..|...
qesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkeleiieekks
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 6-295 | 1e-88 | 292.8 | In-house | 6-285 (288) | alignment | ||
Range on Protein: 6-295
Range on HMM: 6-285/288.0
NLENFLEHYENMAdlsssLDGSDSFELEFNHLKQISQRyrtekvYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTY
..|..|...... ..| .. ||..| .. ...||. |. ||||.||||.|||| || .|.||||||.||....| .....
sveellklvlkll.....angltglleefeellsllpd......ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkf
LAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDeGEEHCFGDILVTQIGQQRvTKDFMIRTLKAT------RDKEEKIFNQFHYTAW
.|.|||||.||..||||.|| |...||| ....|||| ||..|| . |. ..||| || . . .|...|||. | |.|... ..||||.|
IatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnw
PDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
||||||.|....||...|||... . ..|.|||||||.|||||....|.. . |. | . ....... .|.||. .||| .||..|..|...
pdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqleke...ggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 29-318 | 1.5e-88 | 292.8 | In-house | 24-304 (564) | alignment | ||
Range on Protein: 29-318
Range on HMM: 24-304/564.0
SFELEFNHLKQIsqryrteKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNT
.|| |...... . ...| . ..| .||||..|...|||| ||.....|||||.||.|..| ....|.|.||||..|...||||.|| |.
kfeeeykkieeg.......qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqns
EIIVMACNEFELGRHKCERYWVDEGeEHCFGDILVTqIGQQRVTKDFMIRTLKA--TRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEE
..||| . | |..||..|| ..| . .|.. || . .. .|..|||.| ....| . .|||.|.|||||||.| ...||.|. ||.... ..
stiVmltkleEkgkvkchkYWPekg.tetygeltVt.leeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepda
PPIVVHCSAGCGRTGTICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAH-LGIKPEDYGHNYENVQLKH
||||||||| ||||| .|||.. . .. ... .| .. .|||| |.|||..|| .|.|.... .. .. |.. .. .... ..
gPivVhCSaGVGRTGtfividamlerike...ektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkLaeve
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 10-300 | 1e-87 | 289.6 | In-house | 24-303 (308) | alignment | ||
Range on Protein: 10-300
Range on HMM: 24-303/308.0
FLEHYENMADLSSSLDGSDSFELEFNHLKQISQryrtekVYPTSAGESDVNMRKNRYKDILPFDHSRYLLsqidNvEGSDYVNANFLKGA--ANDHTYLA
. ...... | ..... .| ||..| .. ....|... |. |||||||||.|||| | . |||||.||.. .| ......|
lklsvldllkllekaldlglleeefeellsvkp......lleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIa
AQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDE--GEEHCFGDILVTQIGQQRvTKDFMIRTLKATR--DKEEKIFNQFHYTAWPDHG
.|||||.||. ||||.|| |...||| ....| || ||..|| .| |. ..|.. || . .. .|...|||. | |.|... ..||||.|||||
tqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlgdgesrtvthfhytnWpdhg
VPTSVKPILDMIKLVREYQtaEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHL
||.|....||...|||... ...|||||||||.|||||....|.. . |. | ......... .|.||. ||| .||....||...... .|
vPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqleke...ggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 31-300 | 8.4e-87 | 286.4 | In-house | 3-278 (284) | alignment | ||
Range on Protein: 31-300
Range on HMM: 3-278/284.0
ELEFNHLKQISQRYRtekvYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNV-EGSDYVNANFLKGA-----ANDHTYLAAQGPLPHTVNEFWRMLW
| || .| .. . ...|.. |. |||||||||.|||| |. .|. |.|||.||....| . ....|.|||||.||..||||.|
eeefeellsltvkll....lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvw
ECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQQRvTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREY
| |...||| ....| || ||..|| .||| .||. || . . .|...|||. |. ..|... ..||||.|||||||.|....|....||||.
eqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrel
QT--AEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHL
.. ..|||||||||.|||||....|.. . |. |... ........ .|.||. ||| ||..|..|...... .|
lenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 6-298 | 3e-85 | 280.8 | In-house | 8-287 (293) | alignment | ||
Range on Protein: 6-298
Range on HMM: 8-287/293.0
NLENFLEHYENMADlssslDGSDSFELEFNHLKQISQRYRtekvypTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTY
.||.| ||...|. | | |...||.. . ..| |. || ||||..|||.|||| |..... .||||.|||...| . .
klekfeehvkkmka.....dsdlrfseeyeelkavgkdqa......vkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynspref
LAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQQrVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVP
.|.|||||.||..||||.|| ...|||| . .| |. |||.|| .. |.. .||| || . .. ...|..||.|| ...|||. .|.|.|.|||||||
iatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaee.eledwvirelkiekekeerkvrqyhftsWpdhgvP
TSVKPILDMIKLVREYQ--TAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
. |..||... |||.. ||.. ||||||||| ||||| .| . .|.. .. .. |....|..| .||| .|| .|..|.|...
ektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaiee...edyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 34-301 | 3.9e-84 | 277.9 | In-house | 17-281 (317) | alignment | ||
Range on Protein: 34-301
Range on HMM: 17-281/317.0
FNHLKQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVM
|. |.. ..... |....| .| .|. ||||.||||.|||| || ......|||.||.. .| ....|.|||||.||. ||||.|| ....|||
ftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivm
ACNEFELGRHKCERYWVDeGEEHCFGDILVTQIGQQRvTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVV
....|||| ||..|| . ||. .||. || .. . ... .|||. . .|.|. . ..||||.||||||| | ...||....|||.. .. |..|
LteleelgrekcaqYwpl.getltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlV
HCSAGCGRTGTICVIDYVRNALQLEKidqNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHLG
|||||.|||||....... . |. |. ........ .|.||. .||| .||. ...|. .... .|
HCsaGvgRtGtfiaaylmleqlekeg...gvdveeavkelreqRpgavqtpeqyrflydalleylkrklt
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 23-294 | 1.8e-83 | 275.5 | In-house | 7-270 (273) | alignment | ||
Range on Protein: 23-294
Range on HMM: 7-270/273.0
SLDGSDSFELEFNHLKQISQryrtekVYPTSAGESDVNMRKNRYKDILPFDHSRYLLsqidNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRM
.|.|.. ...||..|... ....|... |. |||||||||.|||| | . .||||.||....| ....|.|||||.||..||||
kllgltllleefelllslkp......lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrm
LWECNTEIIVMACNEFELGRHKCERYWVDEGE--EHCFGDILVTQIGQQRvTKDFMIRTLKATR--DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLV
.|| |...||| ....|||| ||..|| .||. . .|.. || .... .|...|||. |. ..|... ..|||| |||||||.|....|..|.||
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielv
REYQTA--EEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
|... | ...|.|||||||.|||||....|.. . |. | ......... .|.||. .||| .||.....|...
rkalealpsngpvvVHCsaGvgRtgtfialdllldqleke...ggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 23-294 | 2.3e-83 | 275.7 | In-house | 22-302 (307) | alignment | ||
Range on Protein: 23-294
Range on HMM: 22-302/307.0
SLDGSDSFELEFNHLKQISQRYrtekVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNV-EGSDYVNANFL--------KGAANDHTYLAAQGPLP
||. .. ||..|... .. ....|.... .|. |||||||||.||.| || .|. |.|||.||.. .| ......|.|||||
lldfltgllkefekllsvtvfl....lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlp
HTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQQRvTKDFMIRTLKAT---RDKEEKIFNQFHYTAWPDHGVPTSVKP
.||..||||||| ....||| ....|||| || .|| ||||| ..|.. || .. . ... .|||. | ..|. . ..||||.|||||||.|...
etvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfee
ILDMIKLVREYQTA--EEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
.||.|..||... . .. |..||||||.|||||....... |. |.. ....|.... .|.||. .||. .||. ...|. .
lldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 37-300 | 4.9e-83 | 274.1 | In-house | 22-281 (297) | alignment | ||
Range on Protein: 37-300
Range on HMM: 22-281/297.0
LkqisqrYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLsqidNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACN
| .. . ...|.... |. |||||||||.||.| | . |||||.||....| .....|.|||||.||..||||.|| |...||| ..
l......lpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmlte
EFELGRHKCERYWVDE-GEEHCFGDILVTQIGQQRV-TKDFMIRTLKATR--DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTA--EEPPIV
..|||| ||..|| .| ||. ..||. || .. . | .|. .|||. | ..|... ..|||| |||||||.|....||.|.|||... . ...|..
lvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvl
VHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHL
||||||.||.||....|.. . |. ... ......... .|.||. .||| .||. ...|. . .. .|
VHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 23-299 | 5.2e-83 | 274.2 | In-house | 27-292 (297) | alignment | ||
Range on Protein: 23-299
Range on HMM: 27-292/297.0
SLDGSDSFELEFNHLKQISQryrtekvyPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNV-EGSDYVNANFLKGAAN-DHTYLAAQGPLPHTVNEFW
.... ..||| .|... ..| ... .|. |||||||||.|||| |. .|.| ..|||.||....| .....|.|||||.||. ||
kansktllllefeellslkp........dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFw
RMLWECNTEIIVMACNEFELGRhKCERYWVDEGEehCFGDILVTQIGQQRvTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVRE
||.|| ....||| ....|||| ||..|| .||. ..||. || .. . .....|||. |...|... ..|.|| ||||||| |.. .|....||||
rmvweqgvtvivmLtklvelgr.kcaqywpeegg..tygdftvtllkveh.ldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvre
YQTA--EEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAH
.. . .. |..||||||.|||||....... . |. | ......... .|.||. .||| .||. ...|...... .
alaelpkggpvlVHCsaGvgRtGtfiaaylmleqleke...ggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 9-298 | 8.5e-83 | 273.0 | In-house | 6-282 (318) | alignment | ||
Range on Protein: 9-298
Range on HMM: 6-282/318.0
NFLEHYENMADlssslDGSDSFELEFNHLKQISQryrteKVYPTSAgESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAA
.. .| ... .|. .. |...|.. .. .| . . ..|| .|||| .||..||.| .|......|||||.|||.. | ....|.||
dleshvrrlre.....sGelllseeyerlsrsee.....tvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaa
QGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEhCFGDILVTQIGQqRVTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPT
|.|||.|...||||.|| |. .||| .| | |..|..||| ..| . .|.. |. . ..|...|..| ||.. |... |.|||.|||.|||.
qaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsr.sygklvvelkee.velsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpe
SVKPILDMIKLVREYQ-TAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
|. .||... |...| .... ||||||||| ||||. ...| . . .. |.. ..... .|.|| ..|||..|||... ..... ..
sgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaeal...vDvfqtvkqlreqrnlmvqtedqyefiydvllealas
|
|||||||||
DSPc_SM00195 | 35-296 | 3.2e-82 | 271.1 | In-house | 7-262 (263) | alignment | |||
Range on Protein: 35-296
Range on HMM: 7-262/263.0
NHLKQISQRYrtekvyPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMA
..|.. . .|. .| . |..|||||.|||.||.| |..... |||||.|||..||| ....| |.|||||.||..|||| || ...||||
ekleestspk......etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
CNEFELGRHKCERYWVDE-GEEHCFGDILVTQIGQQRVTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVV
..|.| |. ||.||| .| |.. ||.| |. . .. . ... .|||. | .. |.. ..|..|..||||||| | |..|.... |.. . ...||||
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
|||||.|||||...||.. . |. || ... .|. .||||. .|||..|| ...|.....
hCsaGvgRtgtfvtidiilskleeekk...vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 35-296 | 3.2e-82 | 271.1 | In-house | 7-262 (263) | alignment | |||
Range on Protein: 35-296
Range on HMM: 7-262/263.0
NHLKQISQRYrtekvyPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMA
..|.. . .|. .| . |..|||||.|||.||.| |..... |||||.|||..||| ....| |.|||||.||..|||| || ...||||
ekleestspk......etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
CNEFELGRHKCERYWVDE-GEEHCFGDILVTQIGQQRVTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVV
..|.| |. ||.||| .| |.. ||.| |. . .. . ... .|||. | .. |.. ..|..|..||||||| | |..|.... |.. . ...||||
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
|||||.|||||...||.. . |. || ... .|. .||||. .|||..|| ...|.....
hCsaGvgRtgtfvtidiilskleeekk...vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 37-293 | 1.7e-81 | 269.0 | In-house | 22-274 (278) | alignment | ||
Range on Protein: 37-293
Range on HMM: 22-274/278.0
LKQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACN
|.. ..... |....| ... |. |||||||||.|||| || ......|||.||....| ....|.|||||.||. ||||.|| ....||| ..
lllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLte
EFELGRHKCERYWVdeGEEHCFGDILVTQIGQQRvTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCS
..|||| || .|| |. ..||. || .... .|...|||. | .|.|... ...||..|||||||.|....||..| |||.. .. |..||||
lvelgrvkcaqYwp..ggsltygdftvtllkeeh.lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCs
AGCGRTGTICVIDYVRNALQLEKidqNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV
||.|||||....... . |. |. ...|.... ..|.||. .||| .||. ...|.
aGvgRTGtfialyllleqlekeg...gvdleeavkelreqRpgavqtpsqyrflyeall
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 25-296 | 6.5e-79 | 260.1 | In-house | 23-297 (306) | alignment | ||
Range on Protein: 25-296
Range on HMM: 23-297/306.0
DGSDSFELEFNHLKQISqryrTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSqIDNVEGSDYVNANFLKGAAN--DHTYLAAQGPLPHTVNEFWRM
. || ||..|.| ..|.. . |. |..||||| ||||||.| |. ..| ||||.|||..|.... |..|.|.|| |..||..||||
lekagfeeefeelqqee....akkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrm
LWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQqRVTKDFMIRTLKAT---RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVR
.|. |...|||. .| | |..|| ||| || |.. .|.| ||.. . . ..|...|.|. . ..|||. |.|...|||||||.. . .||... |.
vwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvn
EYQTAE----EPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
. | . ||||||||| |||||. ||| . . .. ...| .. ..... .|.|| .||| .|| .|..|.
rkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyi
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 24-297 | 4e-76 | 250.8 | In-house | 17-280 (288) | alignment | ||
Range on Protein: 24-297
Range on HMM: 17-280/288.0
LDGSDSFELEFNHLkqisqrYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRML
.. . |. |.| | || ..||. || .||||..|||.|. | | . ....|.||.||....| ....|.|.||||..|||.||..
arnrtgfseeynsL......aalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelv
WECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQQRvTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQT
.| .|. ||| . | |..|||.|| |..... .|.. || .... ..||. |.| ..|.| .|..|.|||||||| | .|.|.... | ..
yenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveske.ledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
AEEPPIVVHCSAGCGRTGTICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
|. ||.|||||| ||||| ..| . .|.. .. . ... .|||| .||| .||| ........ .
adtgpiivhCsaGvGrtgtFialdalidavee...edyiDvagtvaklRkqRallvqtlkqYefiyevllslie
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 51-294 | 6.8e-76 | 250.4 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 51-294
Range on HMM: 2-244/249.0
PTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV
..| .. .|. ||||.||||.|||| || ......|||.||....| ....|.|||||.||. ||||||| . ..|||.....|||| ||..||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
DeGEEHCFGDILVTQIGQQRvTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTA--EEPPIVVHCSAGCGRTGTICVI
. |.. .||. || . . .|...|||. | |.|. ....|| ||||||| |....||.|..||..... .. |..||||||.|||||....
l.ggsleygdftvtllsvev.kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
DYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
... . |. | ....|.... ..|.||. .||. .||. ...|. .
ylmleqleke...lgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 60-293 | 1e-75 | 249.5 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 60-293
Range on HMM: 1-234/235.0
NMRKNRYKDILPFDHSRYLLsqiDNVEG-SDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGEEHC
|..|||||||||.|..| | .. || |||.|||..|| ......|.||||..|...||||.|. ....||| ... | || ||..|| .|.|.
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FGDILVTQI-GQQRVTKDFMIRTLKATRDKEEK---IFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNAL
.||| |. ... .|....|.|. . .|||. ...|.|||.|||||||.|.|..||.|. |.....|.. |.|||||||.|||||....|.. . |
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
QLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV
. |. .....|. .||||. .||. .||. ...|..
eaeee...vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 60-293 | 1e-75 | 249.5 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 60-293
Range on HMM: 1-234/235.0
NMRKNRYKDILPFDHSRYLLsqiDNVEG-SDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGEEHC
|..|||||||||.|..| | .. || |||.|||..|| ......|.||||..|...||||.|. ....||| ... | || ||..|| .|.|.
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FGDILVTQI-GQQRVTKDFMIRTLKATRDKEEK---IFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNAL
.||| |. ... .|....|.|. . .|||. ...|.|||.|||||||.|.|..||.|. |.....|.. |.|||||||.|||||....|.. . |
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
QLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV
. |. .....|. .||||. .||. .||. ...|..
eaeee...vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 55-294 | 3.3e-74 | 244.6 | In-house | 4-241 (245) | alignment | ||
Range on Protein: 55-294
Range on HMM: 4-241/245.0
GESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDeGE
.. .|. ||||.||||.||.| || ... ..|||.||.. .| ....|.|||||.||. ||||||| . ..||| ..|.||||.||..|| . ||
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.ge
EHCFGDILVTQIGQQRvTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQT-AEEPPIVVHCSAGCGRTGTICVIDYVRN
. .||. || .. . .|...|||. | .|.|.. ...||. |||||||.... .||....||... .. |..||||||.|||||....... .
sltygdftvtllseeh.lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
ALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
|. | ...||.... ..|.||. .||| .||. ...|. .
qleke...lgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 57-297 | 1.3e-73 | 243.1 | In-house | 30-273 (278) | alignment | ||
Range on Protein: 57-297
Range on HMM: 30-273/278.0
SDVNMRKNRYKDILPFDHSRYLlsqidnvegsDYVNANFLKGAanDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDeGEEH
|. |||||||||.|||| ||.||....| .....|.|||||.||. ||||||| ....|||.....|||| ||..|| . |.
ylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe.ggsl
CFGDILVTQIGQQRVtKDFMIRTLKAT------RDKEEKIFNQFHYTAWPDHGVPTSV--KPILDMIKLVREYQTA-------------EEPPIVVHCSA
.||. || . ... .|. .|||. | | |. ....||. |||||||.. |..|.... .||.. . .. |..|||||
tygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsa
GCGRTGTICVIDYVRNALqlekiDQNFSLYDIIVDMRKQRHA-IVQTRNQYELVHRAVVDMFQ
|.|||||........ | .....|.... .|.||. .||. .||. ..........
GvgRtGtlvaaylmlell.....eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 30-299 | 4.7e-73 | 240.7 | In-house | 17-279 (281) | alignment | ||
Range on Protein: 30-299
Range on HMM: 17-279/281.0
FELEFNHLKQISQRyrtekvYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE
| |...|..| .. ...| ..| |. ||||..| .|..| ... .. . .||.||||..| ... |.|.|||.|.....||.|.|| . .
fieeyeklaaigvd......ntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvs
IIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQqRVTKDFMIRTLKA-TRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEE-P
.||| .| | |. || ||| |. .| .||. |... . . .. .. |..| ... |.. .|..||||||||||.. | .|. | |..... ..
aivmvtreieagklkChrYWPddnselkygdvtvkstae.eekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktka
PIVVHCSAGCGRTGTICVIDYVRNALQleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAH
|.|.||||| ||||| .| . .|.. . .. .. ... ..||.| .||| ||| |..||.|... .
plvihCsaGvGrtGtyialDrlvkave..aeleeldvkavvaelrkernlmvqtvvqyefvykavldaldke
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 25-296 | 9.1e-73 | 240.0 | In-house | 29-295 (330) | alignment | ||
Range on Protein: 25-296
Range on HMM: 29-295/330.0
DGSDSFELEFNHLKQISQRYRTEkvyptsAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLW
| . | ||| | . . | . . . |..|||. .|||.|.|| ||... || |||.|| |..| . ....|||||. .||..||||.|
ddnklfreefnalPagpiqatle......laskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiw
ECNTEIIVMACNEFELGRHKCERYWVDEGEeHCFGDILVtQIGQQRVTKDFMIRTLK------ATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLV
| .. ||| . | ..||..|| ||| .|.| | .. .. |..|. .| . |||.|.... .|||.|.||| |||. . .|...| |
eqksativmltelkerkeekcaqywPdeGl.vtyGnirv.evedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkv
REYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
.. . . ||||||||| ||||| .|.| | . . | .. ..... .|.|| .||| .|||...... . .
kklnqqsagpivvhcsaGvGrtGtfivldavlerv...kaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 13-298 | 3.5e-72 | 238.1 | In-house | 13-285 (319) | alignment | ||
Range on Protein: 13-298
Range on HMM: 13-285/319.0
HYENMADlssslDGSDSFELEFNHLKQISQRyrtekvyPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPL
.....|. |. ..| ||..||. .. .. . . | .||||..||..|..| ||..|.||||||.||.|. | . . ..|.|.||
rlkalas.....tgetllekefkllkeavnd.......tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPl
PHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWvDEGEEHCFGDILVTQIGQQRvTKDFMIRTLKAT---RDKEEKIFNQFHYTAWPDHGVPTSVK
.|...||||.|| .. |.|| .. | .. |...|| .| . . .| ..|| ... ..|..|| || . | . .|.||.||||.||.. .
entiedfWrmvWeeessivvmltklveklkvklkkyw.peenfeeyGrlivtleeeee.ledyiirklklnkkssevetRevkhfqyteWpdhdvPekat
PILDMIKLVREYQTA-EEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
.||..| .|. . .. ||||||||| ||||| .|.| . . ...| . .. .. .| || .||. .||.... |.... .|
slldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkee...gvlDvfstvsrlRtqRnimvqrpeqYkfiyealleavea
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 30-297 | 2.6e-71 | 235.2 | In-house | 24-287 (307) | alignment | ||
Range on Protein: 30-297
Range on HMM: 24-287/307.0
FELEFNHLKQIsqryrtEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE
.. |...|.. | |...| . | ||||.|| .||. | |..| | |||.||.|.|| . ....|||.|. |...||||..| . .
lakeyekLear......eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevt
IIVMACNEFELGRHKCERYWVDEgEEHCFGDILVTQIgQQRVTKDFMIRTLKATRDKE-------EKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ
.||| |. | |.||..|| .| .| .|||||. . ... ..|..||.|. .. || .. |.|||.|.| || . . .|..|. ||| .
livmlsnlteknrkkcakYWpie.devqygdilvklv.seekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrely
TAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
.. ||||||||| ||.|.. .| . . |..| .. ...... |.|.|| .|| .||. ..||..|. .
klnrsPivvhCsaGvgrsgifvaldsllqqlkae...dkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 15-297 | 2.9e-71 | 235.2 | In-house | 15-291 (298) | alignment | ||
Range on Protein: 15-297
Range on HMM: 15-291/298.0
ENMADLSSSLDgSDSFELEFNHLKQISQRYRTEKvypTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPH
...|. . . . ..|||..|...|.. ..|. ....... | .|||| ||...|.|| .|...|. | |||.|| ||... . ....|.|.||..
qklaavkkkkk.ltgyalefqrlnsvsseieeee...kevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPlte
TVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHcFGDILVTqIGQQRVTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPTSVKPIL
||..||||..| . . ||| | ||.. |...|| |||.|. .|.| |. . .. . |...|.|| .. | .|. |.|.| |||.|||. . .|
tvedFWrmvteedigtiVmltnleeldktkyhkywPdegket.ygeitvs.llskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvl
DMIKLVREYQTA-EEPPIVVHCSAGCGRTGTICVIDYVrnaLQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
|... || .|. . |..|.|||| ||.|| ..|| | |. |..| ..... .||.| ..|||..|| .. || ....
dllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsv...lervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 57-294 | 3.8e-71 | 234.8 | In-house | 7-240 (243) | alignment | ||
Range on Protein: 57-294
Range on HMM: 7-240/243.0
SDVNMRKNRYKDILPFDHSRYLLsqidnvEGSDYVNANFLKGAanDhTYLAAQGPLPHTVNE----FWRMLWECNTEIIVMACNEFELGRHKCERYWVde
. .|. ||||.||||.|||| | |||||.|||. .. . .. | |||||.||.. ||||||| ....||| ....|||| ||..||
lpenlsknrysdilpydhsrvkl......egsdyinanliyvt..p.rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..
GEEhCFGDILVTQIGQQRvTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREY--------QTAEEPPIVVHCSAGCGRTG
||. ..||. || .... ..|...|||. .. |.... ..||..|||||||.|....||... |||. . .. |..||||||.||||
gev.tygdftvtllseeh.lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtG
TICVIDYVRNALqlekidqNFSLYDIIVDMRKQRHA-IVQTRNQYELVHRAVVD
|....... | ...|.... ..|.||. .|||..||. ...|.
tliaaylmllll.......gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 25-298 | 8.5e-69 | 227.2 | In-house | 16-289 (563) | alignment | ||
Range on Protein: 25-298
Range on HMM: 16-289/563.0
DGSDSFELEFNhlkQISQRYrTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGS-DYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRML
|| |. ||. .. .. ..| .... . | ||||| .|...|.|| ||.. ..... ||.|||...| . ..|.||||..|.. ||||.
dgdigfseefe...alqset.iskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmi
WECNTEIIVMACNEFELGRHKCERYWVDEGEEHcFGDILVTQIGQQRV----TKDFMIRT--LKATRD-KEEKIFNQFHYTAWPDHGVPTSVKPILDMIK
|| |..|||| | | ||.||..|| .. |. .| . ||.| .... .. ..|. ||.... ..|| |.||| |||||||.. | | ..|
WeqnvaiivmitnlvergrrkcdvYWPkdeset.ygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvk
LVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
. || ||||||||| ||||| .|.| . . .| |.. ..... .| || .|||..|| .| |.... ..
kssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqena...vnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 37-297 | 1e-67 | 223.3 | In-house | 26-280 (315) | alignment | ||
Range on Protein: 37-297
Range on HMM: 26-280/315.0
LKQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACN
.|| . ...| | .|||| .|...|.|| | ..| ..||||||||..| . . |.|||||.. .|..|||...| . ||| |
fkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltn
EFELGRHKCERYWVDEgeEHCFGDILVTQIGQQrVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAG
| ..|.|.|| |. . .| | ||.. .. | ... .||| . ... . |.|||.||| ||| . |....|. |. ..|.. .||||||||
lvegekrkaekywpdk..kviyGkitvtrksee.vnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaG
CGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
||||| . .| | . .. |.. .|..| .|..| .||. .||.... |... |
vGrtGtfitldavldqaeaena...idvynfitgvrqnrikmvqvaeqyqfiydalletfv
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 37-297 | 1.3e-67 | 222.7 | In-house | 18-276 (280) | alignment | ||
Range on Protein: 37-297
Range on HMM: 18-276/280.0
LKQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNvegsDYVNANFLKGAAND----HTYLAAQGPLPHTVNEFWRMLWECNTEIIV
|.| | || .. .|| |. ||||.||||.|. | |.. .. ||.|||... . |.|.||||..|...||.|.|| ....||
laqfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssliv
MACNEFELGRHKCERYWVDEGEEHCFGDILVTqIGQQRVTKDFMIRTL--KATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIV
| . | || || .|| ....| .|.. |. . ... || ...| | | .. |||. |. |.||||||||.. . .|.... ||......| |.|
mlttlverGrvkChqyWPetedeleygefsvk.cekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvv
VHCSAGCGRTGTICVIDyvrNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
|||||| |||| . ... ||.| . ... ||. || || ..||| .||..| |.. ...
vhCsaGigrtGvlille...talalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvye
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 56-296 | 3e-67 | 221.7 | In-house | 38-290 (297) | alignment | ||
Range on Protein: 56-296
Range on HMM: 38-290/297.0
ESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGE
.. .|..||||.|.| .|..| |...|. | |||.||||. | . ....|.||||..||..||||.|| .. .|||. | || || .|| .|..
klranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleees
EHCFGDILVTQIGQQrVTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQT-------------AEEPPIVVHCSAGCGR
. |||. |... .. ...|...|.|... ...|.. | ...|||.||| | . .||... |||.|. ...|||||||||| ||
saefgdlsvsnveve.eeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGr
TGTICVIDYVRNALQleKIdQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
||| . .|. . |. .. .. . . . .|.|| .|| .|||. . ||..
tGtfitldiclsrle..ev.gtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 48-298 | 6.1e-67 | 220.9 | In-house | 34-285 (305) | alignment | ||
Range on Protein: 48-298
Range on HMM: 34-285/305.0
KVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCER
. .. |....| .|||.|.| ..|..|. |.. .... |||.||....| . ..|..|||||..||..|||...|. .. ||| .. | |..||..
eeesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrq
YWVDEGEE-HCFGDILVTqIGQQRVTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEP-PIVVHCSAGCGRTGT
|| .. | . ||.. |. . ... ..|...| ||.. |||.. |.. | |||||||.. .|..|| |.. | .. |..|||||| ||||.
YWpesktekkefgefsve.lksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGv
ICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
...| . |. | . ..... .|..| .||| .|| .| |. .. ..
fiavdialerlkkE...evvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 33-297 | 4.9e-66 | 217.8 | In-house | 16-270 (273) | alignment | ||
Range on Protein: 33-297
Range on HMM: 16-270/273.0
EFNHLKQISQRYRtekvypTSAGESDVNMRKNRYKDILPFDHSRYLLSQidnvEGSdYVNANFLKGA--ANDHTYLAAQGPLPHTVNEFWRMLWECNTEI
||..|... . .. |... |..||||...||.|..| |.. ||. |.||...| . ..|.|.|||||.||..||.|.|| ..|.
efkelrelkpldt......cevgkkkenkdknryrnvlPydetrvklgd....egg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaev
IVMACNEFELGRHKCERYWVDEGEEHC-FGD-ILVTQIGQQRvTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaEE
|.| .| | |. ||.||| .. ... . . |.....|. ..| .|.|. . . .| . ......|||||||.| ...| ... ||. || ..
iamvtlekekgkvkchrywPesknkklkvsnrlevellkvqk.ldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.da
PPIVVHCSAGCGRTGTICVIDYVrnaLQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
||||||||| ||.||. .|| | |.| . |..| . .|. ..|.||...|||..|| .|..|......
gPivvhcsaGiGrsGtlitidvv...lglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 54-297 | 3.2e-65 | 214.8 | In-house | 3-243 (250) | alignment | ||
Range on Protein: 54-297
Range on HMM: 3-243/250.0
AGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHkCERYWVDEG
.. | |||| ||...|.|| .| . . . |||.|| ||.| . ....|.||||..|...||||..| ... ||| | | .. ...|| |.
vakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvek
EEHcFGDILVTQIgQQRVTKDFMIRTLKATRDKEE--KIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTA-EEPPIVVHCSAGCGRTGTICVIDYVR
|. .||..|. .. . |...|.|| .. |.. .| |.|...||| ||| . .|...| |. | .. |..|.|||| ||.|. ..|| |
aek.yGdvtvsll.skeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavl
NALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
. | |... ....| .||.| |....|| |.... . .
erl...kkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 53-296 | 1.2e-63 | 209.7 | In-house | 13-264 (270) | alignment | ||
Range on Protein: 53-296
Range on HMM: 13-264/270.0
SAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAAN-DHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVD
. | . . |||.|||| ..| |..... . . |.|||...|. . ...|.||.|||| |...||||.|| ... |||. . | ||.||||||
dlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa
EGEE---HCFGDILVTQIGQQRvTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVK------PILDMIKLVREYQTAE--EPPIVVHCSAGCGRT
| .| .|.| |... ... .. .... |. ... ||. |.|..|||||||.. .| |.. ||.... . |..|||||| |||
epkekvkledgkikvlalseek.eegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRt
GTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
||. ..|.. ..|. . .. . || ..||.| |.||. .|||....|||
GtlialDiavrlLeet...kkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 55-294 | 1e-62 | 206.8 | In-house | 38-275 (314) | alignment | ||
Range on Protein: 55-294
Range on HMM: 38-275/314.0
GESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGE
| | .|||..|||..|.|| | .||. |||.||... . . . ....||||..||..|||.... |. ||| . | || || .|| ...|
akkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedte
EhcFGDILVTQIGQqRVTKDFMIRTLKATR----DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVR
.||| |. . . .....|... .. .| .. .||....||||.||.| . .|.... | . | |. .||||||||.||||| ..|| |
v..ygdikvelvet.ellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl
NALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
. .. |.. .. .. ..|... .|.| .|| ... ....
dmieregv...vdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 13-316 | 9.4e-62 | 204.1 | In-house | 19-312 (319) | alignment | ||
Range on Protein: 13-316
Range on HMM: 19-312/319.0
HYENMADLSSSLDGSDSFELEFNHLKQISQRYRTeKVYptsaGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPL
.| ... | | .| ||... ... . . . . | | |||. .||.||... | ... .|.|||.|| |..| . |.||||||
yyqqlsnksdfdddltklevefrracklgvnlad.qtf....anldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPl
PHTVNEFWRMLWECNTEIIVMACnefelgRHKCERYWVDEGEEH-CFGDILVTQIGQqrvTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSV
. |...||||.|| |. ||. ..|| .|| ..... ... |. . . |.....| .. .. |. . .|||. |||.||| .
dntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsvee...taeyvvrdielsedgkekdirkitqfhflGwpdvGvpdyp
KPILDMIKLVREYQTAE--EPPIVVHCSAGCGRTGTICVIDYVRNALQLEKidqNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD-MFQAHLGIKPE
... ..| || .. | . .||||||||.||||. |.| . . .. || .|... |.|.|| .|| || ... |... . .| .
sdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeek...qvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvamp
DYGHNYENVQL
|. .|.
dfpayleelsn
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 47-295 | 1.1e-61 | 203.5 | In-house | 30-275 (515) | alignment | ||
Range on Protein: 47-295
Range on HMM: 30-275/515.0
EKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCE
..|| . . ..| .|||||.|||.| .| | |.. |||.|| .... ||..|.|.|||.. .|..|||.... |. |.| . | . ||
pniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcg
RYWVD-EGEEHCFGDILVTQIGQQRVTkDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICV
.|| | |. || | | . . | . ..|.|. ..... . |||.| |||.||| . .| .|| |. . . |...||||| |||| ..
kyWPdkpgdsvkfGsikvelvsleact.ggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvis
IDYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
|| | | . ..... .|..| .|||..|| ... || .
idsvvaha...kttrmvdvfnfvtnirqkrpylvqtqeqyafiygavled
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 61-294 | 1.4e-61 | 203.0 | In-house | 29-266 (274) | alignment | ||
Range on Protein: 61-294
Range on HMM: 29-266/274.0
MRKNRYKDILPFDHSRYLL-SQIDNVEGSDYVNANFLKGAAN-DHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEE---
.|||||.||| ..|| || |. . | |.|.|||..|| . ...|.|.|||||.||..||||... ....||| . | ..||..|. |. .
qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeis
HCFGDILVTQIGQQRvTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEE---PPIVVHCSAGCGRTGTICVIDyvrNA
. .||. .. . . ..|. .|.| ..|. . ||.|||| .| .....||... |.| ...|. |.||||||| |||| |. .|
erygdveikvekive.rndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiais...ia
LQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
.. . .. . |....| .| .|||..||||.|||..
vrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 48-295 | 1e-60 | 200.2 | In-house | 32-276 (315) | alignment | ||
Range on Protein: 48-295
Range on HMM: 32-276/315.0
KVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCER
..|.. .. ..|..|||||.|||.|..| | ||. |||.|| ..|. .|..|.|.||||. .|..||||... .. ||| . | . || .
diyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrq
YWVD-EGEEHCFGDILVTQIGQQRVTkDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVI
|| | ... || | |. . . | | ..| | . .| . ||..| |||.||. . .| .|| |. . .| ...|||||| |||| .. |
ywPdrkadsvefGsikvellsleadt.dgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisi
DYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
| | . . | . ..... .|..| .|||...| ... || .
devvaqi...krtrsvdvfnfvknlrakrpylvqteeeyafiydavled
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 58-317 | 1e-60 | 200.6 | In-house | 23-277 (284) | alignment | ||
Range on Protein: 58-317
Range on HMM: 23-277/284.0
DVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACnefelgRHKCERYWVDEGEEH-
| | |||. .||.||... | ... .|.|||.|| |..| . . |.|.||||. |...||||.|| |. ||. ..|| .|| .....
dqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivike
CFGDILVTQIGQqrvTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAE--EPPIVVHCSAGCGRTGTICVIDYVRN
... |. . . ......| .. .. |. . .|||. |||.||| . ... ..| || .. | . .||||||||.||||. |.| . .
erfkvkvdsvee...seeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlld
ALQLEKidqNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD-MFQAHLGIKPEDYGHNYENVQLK
.. || .|... |.|.|| .|| || ... |... . .| . |. .|. |
rmkeek...qvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleelsnk
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 47-297 | 2.1e-60 | 199.4 | In-house | 38-285 (297) | alignment | ||
Range on Protein: 47-297
Range on HMM: 38-285/297.0
EKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGaaNDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRhKCE
...|. | ||. |.|||.|||.| || | ... |||||| |.|| | | ... | | . ||..||.|... .. .||| .. | . ||
aniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkg..nkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kca
RYWVDEGEEHcFGDILVTQIGQQRvTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPT--SVKPILDMIKLVRE-YQTAEEPPIVVHCSAGCGRTG
||| |.| |||. |. .. . |. |.|. |..| ... .|.... |||. |. |.. .|..|. ||. ... .| |..|||.|| ||||
ryWsdkgvtt.fGdvsvvllsvse.reGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtg
TICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
.. || | . ... ..... .|..| .|||..||..|. ||....
vlltidsvvaeakr...ekevdifglvkklrqerpylvqtkeqykfvyvavleall
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 38-294 | 3e-58 | 191.9 | In-house | 9-269 (290) | alignment | ||
Range on Protein: 38-294
Range on HMM: 9-269/290.0
KQISQRYRTEKV-YPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNvegsDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACN
|.| . | | .||.. . . | .|||.|. |.|||| | . || ||.||.... .. |. .|||||.||. ||.|.|| .. .|| .
keiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnk
EFELGRHKCERYWVDEGE--EHCFGD--ILVTQIgQQRVTKDFMIRTLKATR--DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ--TAEEPP
| .. || .|| . | | . | . |. | .. ... ...|.|. . .| . .||||.||| ||| | |... ||| . . |
vvekeqikcaqywPqgeeekellledtklkvkli.seerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGp
IVVHCSAGCGRTGTICVIDYVRnaLQLEKIDQ--NFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
|.||||| ||.||.|..| . ...|| |. . . . ....||.|. ..|| .| .. . |...
avihcsaGiGrsGtfclvdtcl..vliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 42-298 | 1.1e-56 | 186.8 | In-house | 39-294 (297) | alignment | ||
Range on Protein: 42-298
Range on HMM: 39-294/297.0
QRYRTEKVYpTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGA-ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFEL
.|..|. ....... |..|||.|..||.|||| |.. . | |||.|| .. .|.|.||||..|| .||.|.|| . .||. .. |
cayeaepst.kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleee
GRHKCERYWVDEGEEhCFGDILVTQIGQQRVTKDFMIRT--LKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCG
| ..|.||| |||.| .. | . . ..|...|. || . .| . |||. .||..|||.| |..|.. . | |||||||.|.|
gvkqckrywpdeGse.vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaG
RTGTICVIDYVRNalQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
|||. ..|| | | .| | .. . . .| ||. .|.|..|.|.. ||.. .|
rtGvyilidlvln..rllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevna
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 57-296 | 3e-55 | 182.6 | In-house | 45-288 (325) | alignment | ||
Range on Protein: 57-296
Range on HMM: 45-288/325.0
SDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRML--WECNteiIVMACNEFELGRHKCERYWVDE-G
|. |||.|.....|.|| | .. |||.||..|. . ...|||| ||..|.|..||.. |.| .|. ||..|| ..| || .| |
kpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcs...vvvvlneldlgkdrcavywpkemg
EEHCFGDILVTQIGQQRVtKDFMIRTLK--ATRDKEEKIFNQFHYTAWPDHGV---PTSVKPILDMIKLVREYQTA---EEPPIVVHCSAGCGRTGTICV
. || . | . . . |.. | |. ... | . .||.. .|.| || |... .||...| | | || ||.|||||| ||||.
ksktfGglevklrtieei.sdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfis
IdYVRNALQLEkiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
. | | .| . . ... . .||.| ..|.| .|| |.. |.|...
l.ysalakvie..esrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 22-295 | 1.3e-54 | 180.0 | In-house | 9-279 (288) | alignment | ||
Range on Protein: 22-295
Range on HMM: 9-279/288.0
SSLDGSDSFELEFNHLKQISQRYrtekVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSqidnVEGSDYVNANFLKGAA-NDHTYLAAQGPLPHTVNEFW
. ||| ... .|. |.| .. .| . .. |||..||||.||.| | . ||.|| |.|. . ...|.|.||. |.|.||
kmldgktaldkkfkeleqkqdke....arkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFW
RMLWECNTEIIVMACNEFELGRHKCERYW-VDEGEEHCFGDILVTqIGQQRVTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKL
.|..| ...||| .. |||..|..||| |.|| . |||. || . ..| |. .. |.|| . . .. | ..|.||..||| | . .|....
lmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvt.lksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqflde
VRE-YQTA---EEPPIVVHCSAGCGRTGTICVIDYVRNALqlEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
|.. |.. . |.||||||| ||||..... . ..| || . . ... .|.||. ||...|.. . ||.
vesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrel..ekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 24-296 | 1.1e-53 | 176.9 | In-house | 16-283 (290) | alignment | ||
Range on Protein: 24-296
Range on HMM: 16-283/290.0
LDGSDSFELEFNHLKQisqryrTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEG--SDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWR
| ..|. .|. |.. .|. . . | . | ..||...|.. | | | .| . . .|.|| ..|| ... |.|.|||...|. .||.
akgnegfrnqfkmlds......gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWk
MLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHcFGDILVTQIGQQRVTkDFMIRTLKATRDKE---EKIFNQFHYTAWPDHGVPTSVKPILDMIKLV
..|. .. |||| .|. | |..|| || |.. .. .| . .. . .. .. ....|.|. . ... ... |.. |.|...| | . || .|. .
liwqekvtiivmltniieegkvkCqqYWpdsdtka.ygefsikllneetln.eyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieem
RE-YQTAEEPPIVVHCSAGCGRTGTICVIDyvrNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
. . .||||||.. ||... |... .... |... ..... .| |. ||| .||..... |. .
yktqrkrgntsivvHCSdtvgrsavfcaaa...ttinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 30-297 | 7.8e-52 | 170.8 | In-house | 12-278 (287) | alignment | ||
Range on Protein: 30-297
Range on HMM: 12-278/287.0
FELEFNHLKQISqRYRTeKVYptSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNvEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE
. |.. ||. | . | .. | | ...|||| |.||.|..| |||. . ||||.|||.. . .|....|||||.. ||..|||...| ..
vdkevdalkeds.esst.atf..kaaeelaavkknryadvlPiddtrvllsaege.lGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsa
IIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQQRVTKDFMIRTLKAT-RDKEE-KIFNQFHYTAWPDHGVPTS----VKPILDM---IKLVRe
... | | .| || .|| . | |. . .. .. .|.|. . .| .. .|... .|||.... . .. .||. |.| |
svitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielar.
yQTAEEPPIVVHCSAGCGRTGTICV-IDYVRNALQLEKIDQNfslyDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
...| |.|||...| ||.|.. . |. ..| ..| ... .|..| |.||. |. |. |.| ..
.dasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdva....avvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 27-294 | 9.4e-52 | 170.9 | In-house | 19-277 (439) | alignment | ||
Range on Protein: 27-294
Range on HMM: 19-277/439.0
SDSFELEFNHLKQISQRYRTEKVYptSAgeSDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWEC
. |. .|.... .| |. . | . . ||||||. .|||.| | .| | | |.|||..|| .|. |.|.||| .|...|||...|
qeifkeifekinstspdyaciasl..aa..qeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviek
NTEIIVMACNEFELGRhkcerYWVDEGeEHCFGDILVTqIGQQRVTKDFMIRTLKAT--RD--KEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ
.| ||| .| .| . || .. | |.||| | . .. ...|| .| || . |. ||||.||||. ||. .||... . .
ktvtivmltnlvesyk.....ywpsda.evcygdiavr.vdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsan
TA-EEPPIVVHCSAGCGRTGTICVIDYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
| |.||||||| |||||| .| . | |.... . |. .||||. .||. || ... ||..
dkeeygpvvvhcsagvGrtGtiialdialeql...klenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 38-297 | 2.3e-51 | 169.6 | In-house | 30-297 (300) | alignment | ||
Range on Protein: 38-297
Range on HMM: 30-297/300.0
KQISQRYRtEKVypTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVeGSDYVNANFLKG--AANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMAC
.|... . . .|... ..| .|||.||.||....| || . ..|.|| .| ......|..|||||..||..||.|.|| ....|||
eripkkre.dal..lstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlt
NEFELGRHKCERYWVDEGEEHC---FGDILVTQIG-QQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILD---MIKLVREYQTAE---
.| | |..|. .|. ...... || ||. .. . . .|| |||. . || ||||||| ||. |. ... ||. . |
eeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves
---EPPIVVHCSAGCGRTGTICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
.||..|||||| |||| . . | . ..|. ... . .. .|.|| .||| ||. |..... ...
keskPPvlvhCsaGvGrtGvlilsdlliatleh...neeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 25-296 | 3.3e-51 | 169.0 | In-house | 17-278 (287) | alignment | ||
Range on Protein: 25-296
Range on HMM: 17-278/287.0
DGSDSFELEFNHLKQISQRyrTEKVyptSAGESDVNMRKNRYKDILPFDHSRYLLSqidnVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLW
|.. |. | |.|..|| ..| . . | |||...||. | | || | ||.|| |..| ... ...|..|. .|. .||....
kgnegfknqftvleqvtqr..edev...thniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWklid
ECNTEIIVMACNEFELGRHKCERYWVDEGEeHCFGDILVTQIGQQrVTKDFMIRTLKATRDK---EEKIFNQFHYTAWPDHG-VPTSVKPILDMIKLVRE
. | ..||| |.| | ...| .|| .| ..|. .. . .. |......|.|. .... ... .|...|.|...| |.. .| . . ...
drnvtaivmlcqekendeevcyqyWpeeks.vvlGeyniellnee.vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemykt
YQTAEEPPIVVHCSAGCGRTGTICVIDYvrnALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
. . .||||||.. ||... | .. ... | . ..... .| |. ||| .||. . .|. .
qrkrgntsivvhCsdtvGrsamfcaaat...tinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyl
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 60-296 | 3.4e-51 | 168.7 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 60-296
Range on HMM: 1-171/182.0
NMRKNRYKDILPFDHSRyllsqidnveGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACnefelgrhkCERYWVdegeehcfg
|. ||||.||||.|||| ..||.|||.. |. . ...|.||||..||..|.|||.| . .||... .|.||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
dilvtqigqqrvtkdfmirtlkatrDKEEKIFNQFHYTAWPDHGVPTsVKPILDMIKLVREyqtaEEPPIVVHCSAGCGRTGTICVIDYVRNAlqlekid
...|. |..|. |||||||. . .||.|. |.| |. |..||||||.|||||........
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.......
qNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
..||.... .|..|. .|.| ||| ....|. ...
.gvsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 86-315 | 6.5e-48 | 159.0 | In-house | 2-244 (272) | alignment | ||
Range on Protein: 86-315
Range on HMM: 2-244/272.0
EGSDYVNANFLKGAAN---DHTYLAAQGPLPHTVNEFWRMlWECNTEIIVMACNEFELGRHKCERYWV-----------DEGEEHCFGDILVTQIGQQrV
. |.|.||....| . ........||||.|...|||. .| . ||. ..|.|.||.||.||| |. ... .|.. || . . .
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllsee.l
TKDFMIRTLKAT---RDKEEKIFNQFHYTAWPDHGVPTSVkpILDMIKLVREyqtaeEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQN-----FS
. |...|.| .| .| . ..|||.|||||||.. .|....|... . |..||||||..||||....... . || | . .
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
LYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHLGIKPEDYGHNYENVQ
|.... .|.||...||| ||. ...|..... ..|....| . . .. ..
leeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaaldaid
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 47-294 | 1.5e-47 | 156.8 | In-house | 32-234 (392) | alignment | ||
Range on Protein: 47-294
Range on HMM: 32-234/392.0
EKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNeFELGRhkce
..||..... ..|..|||||.|||.| .| | ||.. |||.|| .... |...|.|.||| . ....||||... |. |.| . .. |
pdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtk.lkegd....
rywvdegeehcfgdilvtqigqqrvtkdfmirtlkatRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVI
. .. . |||.| |||..|| . .| .|| |. |...||||| |||| . |
.....................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisi
DYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
| | | . ........|..| .|||..|| ... ||..
dsvvaha...kktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 30-292 | 5.9e-47 | 154.7 | In-house | 15-286 (296) | alignment | ||
Range on Protein: 30-292
Range on HMM: 15-286/296.0
FELEFNHLKQISQRYRTEKVyptSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE
|..|.. . .. .| .... .| |. |||. ...|.|. | .|...| | |||.|| . . .. |. ..| .||.||||.... ...
frveyklelkltprleigdC...agglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeis
IIVMACNEFELGRhKCERYWVDEGeEHCFGDILVTQIGQQRVTkDFMIRTLKATRD------------KEEKIFNQFHYTAWPD-HGVPTSVKPILDMIK
.|. ...|. . .. || .. .. .|.|.| . .. . .. |||.| |. |..| .|..| |. . || | . ......
avvvLtktfdfak.mypsywpnks.keqygeifveiveekqya.nlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrr
LVREYQTAE-----EPPIVVHCSAGCGRTGTICVIDYvrnALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAV
|| .. | |.||..| | .|.| . || .|.| ...... ... . .|..| .|.. ..| . .
rvrlwrekvdedpeegPvvvvssdGasRsGvylaida...nlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 57-294 | 4.4e-46 | 152.0 | In-house | 4-238 (239) | alignment | ||
Range on Protein: 57-294
Range on HMM: 4-238/239.0
SDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGA-ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEE
|| |||| .|. .|||| .| .. | |||.||..|. . ..|.|.|| . . .||||.|. .||| | ..|| .|| | .
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk
HCfgDILVTqIGQQRVTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVrnaL
.| .. || . . | |..|||. . . ||. |.|.| |||.||| .| . . . . | |.||||| ||||.. ||| . |
yc..nlrvt.lrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidam...l
QLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
. | .. ... . .|..| .||| .|| ..| ||..
rqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 56-293 | 4.7e-46 | 151.9 | In-house | 4-238 (239) | alignment | ||
Range on Protein: 56-293
Range on HMM: 4-238/239.0
ESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGA-ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGE
. || |||| .|. .|||| .| .. | |||.||..|. . ..|.|.|| . . .||||.|. .||| | ..|| .|| |
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts
EHCfgDILVTqIGQQRVTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVrna
..| .. || . . | |..|||. . . ||. |.|.| |||.||| .| . . . . | |.||||| ||||.. ||| .
kyc..nlrvt.lrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidam...
LQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV
|. | .. ... . .|..| .||| .|| ..| ||.
lrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 58-298 | 4.7e-45 | 148.9 | In-house | 39-279 (307) | alignment | ||
Range on Protein: 58-298
Range on HMM: 39-279/307.0
DVNMRKNRYKDILPFDHSRYLLSqIDNVeGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYW-VDEGEEH
. | ||||.|. |..| .. .| . |||. ||.| | . . ...||||| |. .|| | . . | ..| |. ||.. |||.|| ..||..
santdknryqdvkcqdkgrivvk.fdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqkl
CFGD----ILVTQIGQQRVTKD---FMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVReyqtAEEPPIVVHCSAGCGRTGTICVIDYV
||. | |...| .... | . ||| .. . ... .. |||.||| ..... || .. |.||||||| ||.||| | .|
vfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr....ydtnpvvvhcsaGvGrsGtivaislv
RNALqLEKIdQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
.. . .. | .. ... ..|.||| .|| || .|| ... |
qdkm.iaGi.nckdmkklveelrsqrhyaiqteaqylylhrvlleyfle
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 60-293 | 7.1e-45 | 148.1 | In-house | 3-236 (237) | alignment | ||
Range on Protein: 60-293
Range on HMM: 3-236/237.0
NMRKNRYKDILPFDHSRYLLSQIDnvEGSDYVNANFLKGAA-NDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCF
| |||| .| .|||| .| ||||.||..||| ..|.|||||| . ..||.|.|. . .||| | . || .|| . . ..
nkiknrygnivaydhsrvvlkgag..sgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GDILVTqIGQQRVTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVRE--YQTAEEPPIVVHCSAGCGRTGTICVIDYVrnaL
| . |. . .. |. .|.| .. || .. |...|.|||.||| .| . | . . .| | ..||||| |||| . ||| . |
gvltvs.lkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidam...l
QLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV
. | . .|. . . ..| |.||..|| ..|....
rqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 85-293 | 4e-44 | 145.8 | In-house | 9-170 (176) | alignment | ||
Range on Protein: 85-293
Range on HMM: 9-170/176.0
VEGSDYVNANFLKGAAndhtYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCfgdilvtqigqqrvtkdfmirtlkatr
...||.|||.. |.. ..| |||||.|. .|..||.| . ...|. ..|.||||.|| .|| .. ....
dldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...........................
dkeekifnQFHYTAWPDHGVPTSvKPILDMIKLVREYQTAEePPIVVHCSAGCGRTGTICVIDYVRNalqlekiDQNFSLYDIIVDMRKQRH-AIVQTRN
|.... |||||||.. . .|......||.... |..||||||.|||||..... .. ....|..... .|.||. .|||..
........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel.......ekglsveealalvreqRplgavqtpe
QYELVHRAVV
||. .....
Qyrflyefel
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 86-289 | 5e-44 | 145.4 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 86-289
Range on HMM: 3-154/172.0
EGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEfelgrhkcerywvdegeehcfgdilvtqigqqrvtkdfmirtlKATRD
|||||.||..|.. . ..| ||||..|...|||||.| . .||..... ...
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
KEEKIFNQFHYTAWPDHGVPtSVKPILDMIKLVRE-YQTAEEPPIVVHCSAGCGRTGTICVIDYVRnalqlekidQNFSLYDIIVDMRKQRHAIVQTRNQ
..|. |..|. ||||||| . . .|.......| .. .. |..||||||.|||||........ ...||.... .|..| .||. .|
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.........lglsleeavalvrekRpgavqnpsq
YELVH
| ...
yrfly
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 58-297 | 6.7e-44 | 146.2 | In-house | 44-281 (314) | alignment | ||
Range on Protein: 58-297
Range on HMM: 44-281/314.0
DVNMRKNRYKDILPFDhSRYLLsQIDNVEGSDYVNANFLKGAandHTYLAAQGPLPHTVNEF----------WRML--WECNTEIIVM------------
.|. ||||.||||.| .|. | . .|.|||| ||....| ...|.||||..||. | ||| .. |. .|||
flnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsr
---------ACNEFELGRHKCERYWVDEGeehcfgdilvtqigqqrvtkdfmirtlkaT----RDKEEKIFNQFHYTAWPDHGVPtSVKPILDMIKLVRE
.. ..| . ..... . . ... |. ..... .||...| . . .........|
LdaAlgKtpllildgngneptaadlellk.............................eelydpelferlgikylripvpDgsap.lledfdeflefiee
YqtAEEPPIVVHCSAGCGRTGTICVIDYVRNALqlekidqNFSLYDIIVDMRKQRH-----AIVQTRNQYELVHRAVVDMFQ
. .. |..|||.||.||||| .|..|. .| ..|| ... |.|..|. ... .||| ...|. . ..
a..dkggpvlvHCkaGkgRtgtfvvaaylmkll.......gvsleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 57-296 | 2e-43 | 143.1 | In-house | 53-283 (290) | alignment | ||
Range on Protein: 57-296
Range on HMM: 53-283/290.0
SDVNMRKNRYKDILPFDHSRYLLSqiDNVEGsDYVNANFLKGAanDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVD-EGEE
. ...||||||. | .| .|. | .| ||| ||..|| . ... .||.| || ..|||. . .. ||| |. .| |. |||.|. . |||
kntefkknrykdvvcndktrvilk..dGydG.dyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGev
HCFGDILVTQIGQQRVTKDFMIRTLKATRDKE--EKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaeepPIVVHCSAGCGRTGTICVIDYvrnAL
||.| |. .. .. . .|| .. |.... .. .|||. |. | .| ... .|. |.||||||| |||||. |. .|
ltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkasG....pvvvhcsaGiGrtGtfvaiev...gl
QLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
|. ... | |.. .|. | . || || .. ....|.
qilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlG
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 87-289 | 2.2e-43 | 143.3 | In-house | 1-163 (174) | alignment | ||
Range on Protein: 87-289
Range on HMM: 1-163/174.0
GSDYVNANFLKGAANDHTYLAAQGPLPhtvneFWRMLWECNTEIIVMACNEFELGRHKCERYWVDegeehcfgdilvtqigqqrvtkdfmirtlkaTRDK
|||| ||..|.. ..| ||||. ||.||.| . ...|| ..|.|||..|| .|| . .|.
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
EEKIFNQFHYTAWPDHGVPTSVKpILDMIKLVREYQTA-EEPPIVVHCSAGCGRTGTICVIDYVRNALQlekiDQNFSLYDIIVDMRKQRHAIVQTRNQY
.|. |..|. |||||||.. . .|...|.|.|.. .. |..||||||.|||||....... | .|.. .|.||. .||| .||
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll....eslvdaldlvrelRlqrpgmvqtpsQy
ELVH
. ..
rfly
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 46-246 | 4.9e-43 | 142.4 | In-house | 31-249 (418) | alignment | ||
Range on Protein: 46-246
Range on HMM: 31-249/418.0
TEKVYP--TSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANdHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRH
| | | || |. | |||| .||| .|.| | .|.. |||||.|||.. || . ....||||| |. .||||.|| |||| | | |
eesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresencri
KCERYWVDE--GEE--------HCFGDILVTQIG-QQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTA------EE
||.||| .. ||. || | . | .. . | .. | . | . |..| |||| .| .|. .... . . | .
kcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrn
PPIVVHCSAGCGRTGTICVI
||.|||||| |||||.|
vpiivhcsagvgrtgtfcta
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 96-289 | 1.5e-42 | 140.1 | In-house | 2-143 (152) | alignment | ||
Range on Protein: 96-289
Range on HMM: 2-143/152.0
LKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWvdegeehcfgdilvtqigqqrvtkdfmirtlkatrdkeekifnQFH
..| |. . ..|.|||.|.|...|||||.| . .||| ....|||. |||.|. |..
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qyl
YTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRnalqlekidQNFSLYDIIVDMRKQRHAIVQTRNQYELVH
.. |||||||.. .|.......... .. |..||||||.|||||........ ...||.... .|..| .|.. .|.....
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.........lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 26-297 | 5.3e-42 | 138.5 | In-house | 22-290 (305) | alignment | ||
Range on Protein: 26-297
Range on HMM: 22-290/305.0
GSDSFELEFNHLKQISQRYRTEKVYPTsAGESDVNMRKNRYKDILPFDHSRYLLsqiDNVEGSDYVNANFLKGA-ANDHTYLAAQGPLPHTVNEFWRMLW
| | . || .| . .. |.... . .|... ||||.|. |.| .| |. |||. ||.. .. ...||||| .|..||| |.
gvdklreefrglakytrpdmtqvafna.nqsadiaitknryqdvpcqdqsavkl...dkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmvi
ECNTEIIVMACNEFELGRHKCERYWV-DEGEEHCF-GDILVTQI-GQQRVTKDF--MIRTLKATRDKEEKI-FNQFHYTAWPDHGVPTSVKPILDMIKLV
. . | ||| |. |||. || .|| || . . . |.| .. | . . .| | .|. | ..|. ....| ||| ||| |... .
qnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsai
REYQTaeepPIVVHCSAGCGRTGTICVIDYVRNALQLEKidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
| . ||||||||| |||||| |.|. . . .| . . ... .| || .|. || .|| ... |
rgskv....pivvhcsagigrtgtivaieyilekiaenk..pcppmpelvkalrdqrafsiqndvqylfihrvmlnyfl
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 29-294 | 5.3e-42 | 138.6 | In-house | 7-264 (283) | alignment | ||
Range on Protein: 29-294
Range on HMM: 7-264/283.0
SFELEFNHLKQISQRYrtekvYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNvegsDYVNANFLK---GAANDHTYLAAQGPLPHTVNEFWRMLWE
...| .. ||..| .. .| | ||||...|.| | | | . ||.|| |. .|. |..||.|| .|| .||.|...
nnklfrevlkrlsvpd.....ldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfd
CNTEIIVMACNEFELGRHKCERYWVDEGEEHcFGDILVTqIGQQRVTKDFMIRTLKATRD---KEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ
. ||| . | | || .|| .| | .|. || . .. . |.|. | . |.. . . . | . | . . .. . |.. .
ekitaivmltklqedlrikCsqyWPkrGsed.yGeftvt.lrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqt
TAEEPPIVVHCSAGCGRTGTICVIDY-VRNALQLEKIDqnfsLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD
.. |||||||.| |||.. . . | .|| .| .. .. ||.|| .|||..|| ||| .|..
eskkgPivvhCstgiGrtavfiaasasvkdaltesvvd....vfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 38-297 | 2e-41 | 136.7 | In-house | 18-294 (301) | alignment | ||
Range on Protein: 38-297
Range on HMM: 18-294/301.0
KQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDN--VEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMAC
.. .. .... ... | |. | . ||.|.| ..|. | .|.. | . .|.||....| . . . |||||. .|. .|||..|. . ||| .
eeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvt
NEFELGRHKCERYWVD-EGEEHCFGDILVTQIgQQRVTKDFMIRTLK-----------------ATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMI-K
|. | ..|||.|| . | |.. || . || . .. | ||.|| |. ..||. . |.. | ||..|| . .| | .
nlkegtkskceqywpnseaeseefgpftvtlv.neqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqvidd
LVREYQTAEEPPIVVHCSAGCGRTGTICVIDYvrnALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
. | . |.|||||.. .|.|. | .. .| | . ..... .|... |.| .|| .. .. ..|
vihrqqkigggpvvVHCSdtVsrsGvYcsvsi...glEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylq
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 56-299 | 2.1e-38 | 126.6 | In-house | 33-272 (281) | alignment | ||
Range on Protein: 56-299
Range on HMM: 33-272/281.0
ESDVNMRKNRYKDILPFDHSRYLLSQ-IDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGE
. || .|||| .| .| || | . | . .||. ||... . |. .||| | .||||.|. || ||| |. | | || |. .
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
EHCFGDILVTQIGQQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPildMIKLVREYQTAEEPPiVVHCSAGCGRTGTICVIDyvrnaLQ
| | . . | | .. |. . . | .. .. . ||| || | . |.|..|. .. || |.||||| ||.||. .. .
cclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessev...mlkilrkirarstpp.vihcsagvgrsgtlmave.....ia
LEKIDQNFSLYDI---IVDMRK-QRHAIVQTRNQYELVHRAVVDMFQAH
|. | |.| || . .| | | ||| .|| |. . ..|. |.
lqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfgvay
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 55-294 | 4.2e-38 | 125.9 | In-house | 28-293 (297) | alignment | ||
Range on Protein: 55-294
Range on HMM: 28-293/297.0
GESDVNMRKNRYKDILPFDHSRYLLSQidNVEGSDYVNANFLKGAA--NDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVD-
. .|||||.||| .| .| | . . ..||.||... .| |. ||||| ||..||....| . .||| .. | ||.|| || .
akrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsv
EGEEHCFGDILVTQIGQQRVTKD-FMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSV-----------------KPILDMIK-------LVREYQTAEE
..| ||..| . . | .. |. .|.. . . .|||||||. . .| ... | | ||
vqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraem
P---PIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSlydIIVDMRKQRHAIVQTRNQYELVHRAVVD
| ...|||||| ||.| . | . . |. ..| . . |. .|.|| .||| .|.||.. ||.
prnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaa...ilsilreqrarlvqtleqfellydavlk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 71-290 | 9.3e-38 | 125.0 | In-house | 1-165 (178) | alignment | ||
Range on Protein: 71-290
Range on HMM: 1-165/178.0
PFDHSRYLLSQIDNVEGSDYVNANFLKgaanDHTYLAAQGPlphtvNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEehcfgdilvtqigqqr
|.|..|.||| . ..|.||| ||.. .. ||....| .....|.| . ||. ..|.|||..|| .||..| .
pldrtrvllsnleglersdyinaseil....pglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
vtkdfmirtlkatrdkeekifNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNAlqlekidqNFSLYDIIVD
|.... .||||||.. . .|.......|.. .. |..|||||| ||.||........ ..||...|
.....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl........glsleeaiel
MRKQRHaIVQTRNQYELVHR
.|..| ||....|.. ...
vrerRp.ivpnpgqlrqLye
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 60-298 | 2.1e-37 | 123.5 | In-house | 48-289 (305) | alignment | ||
Range on Protein: 60-298
Range on HMM: 48-289/305.0
NMRKNRYKDILPFDHSRYLLsqiDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVD-EGEEHCF
. ||||||. .|. | | .. .|. ||.. .| . .. .| || .| .|| | .. . | | | || | | .|| |. .... |
eagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlef
GD--ILVTQIGQQRVTKDFM-------IRT---LKATrDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYqtaeEPPIVVHCSAGCGRTGTICVI
. .. . || .| .| .. . .. . ...|. ||| |||.. ||.... | ||||||||| ||||.. ..
eekgqkisvkfessvtlkfrkdakakvtetvlviegp.gekarkvthyhwidwpdrgvpaadlailellekarps....kgpivvhcsagigrtgsvvml
DYVRNALQLEK-IDQNfslYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
.|. . | . |.. |.. .|.|| .|| .|| .||. ....|.
eyildqllagqiiedt...dkilqkireqrnnsiqtdaqylfvhqvilnyfrk
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 60-295 | 1e-36 | 121.5 | In-house | 43-270 (288) | alignment | ||
Range on Protein: 60-295
Range on HMM: 43-270/288.0
NMRKNRYKDILPFDHSRYLLSqidnVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYW-VDEGEEHCF
| ..||... | .| || . |..|| . | ... . || || |..|.|.|| | . | ||| |. |.|..| . |. . ||. .
nptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekari
GDI-LVTQIGQQRVTKDFMIRTLKATRDKEEKI-FNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaeepPIVVHCSAGCGRTGTICVIDYvrnALQLE
| . |.. .. . | . .|. .. |||. . |. |.|.||| . .. | ... ....| |||||.||| |||||. .| ||.
grlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk....PivvhssaGvGrtgtlilili...alesl
KIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
..| . .. .. .|..| .|| .|| ||| | .
rlddflgirsllaklreerfkaiqtemqylyvhrcvlee
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 60-293 | 1.4e-34 | 114.1 | In-house | 52-287 (310) | alignment | ||
Range on Protein: 60-293
Range on HMM: 52-287/310.0
NMRKNRYKDILPFDHSRYLLsQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFG
.| |||| |.. | || | .||. ||. ||..| |.. .|||| ||. .||||... .| |.. |. | || || || | .|
ymhknrysdvvcldtsrvkl.kidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetyg
DILVTQIGQQrvTKDFMIRTLKATR------------DKEEKIFNQFHYTAWPDHGVPTSVKPILDMiKLVreyQTAEEPPIVVHCSAGCGRTGTICVID
| ||.... ...| | | | . .| . .. ||| ||| . .|. | ||||||| .|..... ..
cirvtnlses..seefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpq.rll...aqvrhgpcvvhcsagkdrlyvvvalk
YVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV
. . |. .. . ... ...|.| .|| || ...| .
lkidkldr...glkvdaeevktellksraiciqtelqyliidrvri
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 27-298 | 7.7e-34 | 111.9 | In-house | 5-261 (267) | alignment | ||
Range on Protein: 27-298
Range on HMM: 5-261/267.0
SDSFELEFNHLKQISQRYRTEKVYptsAGeSDvNMRKNRYKDILPFDHSRYLLSQIDNVegsdYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWEC
..| ||. .|.||. | . . .. | .||. | ||.|..| |.. .. |.|| ...| ..... |.|| |. .|. .. .
eceiekefelikkisdtsstisqs...ia.ek.nqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdq
NTEIIVMACNEFElgrHKCERYWVDE-GEEHCFGDILVTQiGQQRVTKDFMIRTLKAtRDKEEKIFNQ--FHYTAWpdhGVPTSVKPILDMIK--LVREY
. .||. . |. . ..| . |. . . |. | . .. .|. | ||. . |.| .| ..| | . | || | . | ..
kvpvivlltkvft...dnirlfwPPkmgqakkyqdltveh.slekeendyqiitlel.kfknesahnvtlyyykkw...nintnnkpylkplfgilaknq
QTAEEPPIVVHCSAGCGRTGTICVIDyvrNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQA
..|.||.||.| ||.|| ||| |. | .. ..| . .|.|| ..|.|...| .|. ... .
lengnrPlvvacsdGvGrsGtflvid...sqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyaeg
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 57-296 | 5.2e-33 | 109.2 | In-house | 32-270 (285) | alignment | ||
Range on Protein: 57-296
Range on HMM: 32-270/285.0
SDVNMRKNRYKDILPFDHSRYLLSQIDNvegsDYVNANFLKGAAND-HTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDE-GE
. | ||| |. . .| .| . | ||. |.... .| ||...||||| |...||.|... . ..| | || | || |. .. ||
yeanpdlnryadvrcieetrvvlknhdr....dyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
EHCFGD--ILVTQIGQQRVTKDFM-IRTLKATRDK--EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAeEPPIVVHCSAGCGRTGTICVIDYV
|| | .|. .. .. . |. | | | .|. . |||. | .|.... | |.. . | ||.|||||| ||| |. |||
vvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk.ekpicvhcsagvgrtatfvgidya
RNALqLEkiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
. .| . | . ||. .|| | ||.. |. ... ... |
tiri.me..npniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
PTPc_DSPc_SM00012 | 192-293 | 2.8e-32 | 106.4 | In-house | 3-104 (105) | alignment | |||
Range on Protein: 192-293
Range on HMM: 3-104/105.0
NQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEE--PPIVVHCSAGCGRTGTICVIDYVRNALQLEKidQNFSLYDIIVDMRKQRHAIVQTRNQYELVH
...|||.|||||||.....||.... |.. ....| .|.|||||||.|||||....|.. . |. |. .......|. .||||. ||| .|| ..
khyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket..kevdifqivkelrkqRpgmvqteeqylfly
RAVV
||.
rall
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 87-291 | 5.1e-32 | 105.9 | In-house | 2-148 (151) | alignment | ||
Range on Protein: 87-291
Range on HMM: 2-148/151.0
GSDYVNANFLKGAandhtYLAAQGPLPhtvnEFWRMLWECNTEIIVMACNEFELGrhKCERYWVDEGeehcfgdilvtqigqqrvtkdfmirtlkatrdk
||| |.... | ... .|||. .|...|.| . ||. ..|.| | .| .|. ..|
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
eeKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREyqtAEEPPIVVHCSAGCGRTGTICVIDYVRnaLQlekidqnFSLYDIIVDMRKQRHAIVQTRNQYE
. ..... |||.|.|.| . .|....|... .. |..||||||.|||||..... . |. .||.... ..|..|. .||. .|.
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylml..lg.......vsleealeeyrlkrpgvvqpnqqfl
LVHRA
....|
fqlfa
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 63-299 | 7.5e-31 | 102.0 | In-house | 46-279 (312) | alignment | ||
Range on Protein: 63-299
Range on HMM: 46-279/312.0
KNRYKDILPFDHSRYLLSQIDNVegsdYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVD-----EGEEHC
||| .| .| |. |. .| |. |||.| .. ....|||| |. ||.. . |.. | | | .|| .| | . |.|
lnrypniqcwdrgrftlagdenf....yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhr
FGDILVTQI-----GQQRVTKDFMIRTLKATRdKEEKiFNQFHYTAWPDHGVPTSVKPILDMIKLVREyqtaEEPPIVVHCSAGCGRTGTICVIDYVRNA
.|.| ....|. . .||| .| | .|.. ...|||||.| |. | .. |. . |.. ||||| |||||...|. . |
vyteycteieiggkskdkithrvlkvvvkatg.qesk.lnhyqwaswpdhgmpdscdtalrllsavkk....dkkpviahcsagvgrtgtlaliesmiaa
LQLEKiDQNfsLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAH
|. . || . |. | .||.| |.. || . |.|.... ..
lrhpr.kqn..vkdsfvllrkdrarsvrvfpqyvyalrcvleflysk
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 91-285 | 4.1e-29 | 96.3 | In-house | 78-270 (301) | alignment | ||
Range on Protein: 91-285
Range on HMM: 78-270/301.0
VNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDE-GEEHCFGDILVTQI-GQQRVTKDFMIRTLK---ATRD
. ||... . | ..|.||||. | ..|| || . | ||| ... | .||| | . .|. | .. .. . |. . |||. .|..
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
KEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREyqtaEEPPIVVHCSAGCGRTGTICVIDYVRNALQlekIDQNFSLYDIIVDMRKQRHAIVQTRNQY
. . . |. |.|.||| | . |...||.. | ||||||||| ||. . .|. .... |.. | . . ..|..| |||..|
fatrtvthyqysewtdrgvPkshaelfdlmelvkk....sekPivvhcsaGiGrsvafigteylareve...adptieltealkhlrehrwngvqtnsql
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 61-219 | 7.7e-27 | 88.8 | In-house | 29-191 (319) | alignment | ||
Range on Protein: 61-219
Range on HMM: 29-191/319.0
MRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDH-TYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDE--G-EEH
|.|. ...|. ..| | .| . . . |..|....| . . |.||| .| . .|||..|| .. .|| ... .||| ..| .|. . . ...
kdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnts
CFGDILVTQIGqQRVTKDFMIRTLKATRDKEEKIFNQFH--YtAWPDHGVPTSVKPILDMIKLVR
.|||||| | . | . ..| || | ..|. . | | |.. .||.. .... |. ||
lyGdilvtlkg.revkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 175-292 | 1.1e-26 | 88.6 | In-house | 31-139 (145) | alignment | ||
Range on Protein: 175-292
Range on HMM: 31-139/145.0
FMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEePPIVVHCSAGCGRTGTICVIDYVRNalqlekidQNFSLYDIIVDMRKQ
.. .| ... .|. |..|. |||||||.. . .|.......|.. .. |..||||||.|||||..... .. ...||.... .|.|
ttvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll........lgvsleealelvrsq
RHAIVQTRNQYELVHRAV
|. .|.. .|.. .....
rpgavpnpgqlrflyefe
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 176-290 | 2.1e-25 | 84.5 | In-house | 32-139 (144) | alignment | ||
Range on Protein: 176-290
Range on HMM: 32-139/144.0
MIRTLKATRDKEEKIFN--QFHYTAWPDHGVPTSVKPILDMIKLVREYQTaEEPPIVVHCSAGCGRTGTICVIDYVRnalqlekiDQNFSLYDIIVDMRK
.. .| ....|. ... |.... |||||||.. . .|.......|.. |. |..||||||.|||||..... .. ...||.... .|.
tvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaaylmk........klglsleealalvrs
QRHAIVQTRNQYELVHR
.| .|....|.. ...
rrpgavpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 110-286 | 5.4e-25 | 82.4 | In-house | 98-278 (302) | alignment | ||
Range on Protein: 110-286
Range on HMM: 98-278/302.0
GPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDE-GEEHCFGDILVTQIG------QQRVTKDFMIRTLKATRDK----EEKIFNQFHYTA
| |.. .| .. . |. |.| |. | . .|| |. |. |.| || |. . . |.|.. |.. . .| .| . ....|
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDHGVPTSVKPILDMIKLVREYQTAeeppIVVHCSAGCGRTGTICVIDYvrnALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYE
||||| | .. ||..| |... ..|||||| |||||. | | .|| . .. | .|.. .|. |. ||. .|
wpdhGapkeaytaldilkfcesykkn....vlvhcsaGvGrtGtlvaiky...GiqlcskkkvtdllsivlpvrqcryGavqdeqqli
|
|||||||||
subfamily_egg_pd | Subfamily egg | 39-303 | 2.3e-23 | 77.4 | In-house | 21-277 (307) | alignment | ||
Range on Protein: 39-303
Range on HMM: 21-277/307.0
QISQRYRTEKVYPTSAgeSDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEF
.... |. . |.| || |. | | | . | || | |.. || .|| ... || || ||..||||... . . |||
evleesvdeislttaa..sdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrk
ELgrHKCERYWVD-EGEEHCF--GDILVTQIGQQ-RVTKDFMIRTLKATRDKEEKIFNQFHYTawpDHGVPTSVKPILDMIKLVREYQTaeepPIVVHCS
| ..|| || | . . | . .. .. . . | . || ..|. | . | . | | .....|. . |.||..
es..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg...dvnnssdvysplrvlrklrnlsk....pvvvqdi
AGCGRTGTICVIDYVRNALQLEKIdQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHLGIK
|. ...|. |. | | . . .| .|..|. |.. .| .|.| |. .|. .|
lGvskaatlvaieiallsllrGpi.tkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigsa
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 62-152 | 2.3e-23 | 77.5 | In-house | 49-153 (350) | alignment | ||
Range on Protein: 62-152
Range on HMM: 49-153/350.0
RKNRYKDILPFDHSRYLLS--------QIDNVEGSDYVNANFLKGA------ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCER
|||||.|||..||| | . ....||.|||.|| . |. |.|.|.||| ||..|.... . . ..|.. ...||...||.|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWVDE
|| .
YWqeg
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 187-325 | 3e-23 | 76.8 | In-house | 87-224 (440) | alignment | ||
Range on Protein: 187-325
Range on HMM: 87-224/440.0
EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ-TAEEPPIVVHCSAGCGRTGTICVIDYV-RNAlqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQ
| . ..|.|| .|||.||| . |.| ||. | | | | . |..||||||.|||| | ..| . |.| | .. .. .| ||..| .||| .|
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilrea....krsdqidifsfinsmrnnrpqmvqtpeq
YELVHRAVVDMFQ-AHLGIKPEDYGHNYENVQLKHEHFEQPR
| .|| ||.. . . | .| . |..| | ..
yafvheavlegllcgdtliledditerveqiqwpnphtdksp
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 59-292 | 5.3e-22 | 72.8 | In-house | 46-275 (303) | alignment | ||
Range on Protein: 59-292
Range on HMM: 46-275/303.0
VNMRKNRYKDILPFDHSRYLLSQidnvegSDYVNANFLKGAANDHTYLaAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCF
|| |||. |.. .|||. ||. | |. |..|. .. .. | .| ||.|| .||.|. | . ... . | . . . . . |
knmdknrfvdvicldhskvklsd......ssyihasyleldsskkail.tqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkf
GD--ILVTQIGQQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTS-----VKPILDMIKLVREYQTAeEPPIVVhCSAGCGRTGTICVIDYVRN
. | | .. . ... . .. | . . .. || ||| .|. || | .. ..| | . .|.. . .||||.||.....
eersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysds.tptvym.slsgcgragtfalfetahl
ALQLEKidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAV
.|. |. . | . .|. | || |. .|. .
slhseq..asldlvkclenvrngrlhavqnlsqfsvvytll
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 115-296 | 5.4e-20 | 66.5 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 115-296
Range on HMM: 40-221/255.0
TVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEG-EEHCFGDILVTQIGqqrVTKDFMIRTLKATR----DKEEKIFNQFHYTAWPDHGVPTSVK
||..|.... .|| .|| |. | |. ||..|. | | . |. || . | ..|||. | |. . . ..|. |... | .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelar
PILDMIKLVREYQtaeepPIVVHCSAGCGRTGTICVIDYVRN--ALQLEKID-QNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
|| ..|.||. . ..|||||.| ||. . ....| ..|.. . .. .. ..|..|.. ..| | . |.|..
eilnilkvvrdsk.....svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 190-297 | 5.3e-18 | 59.9 | In-house | 216-345 (350) | alignment | ||
Range on Protein: 190-297
Range on HMM: 216-345/350.0
IFNQFHYTAWPDHG---VPTSVKPILD----MI---KLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRN-ALQLEKIDQNF-------SLYD----I
. |... |.| . | |. ..|. .| ...|. .||.||||||.|||||.. .|.. . . ||.. ... . | |
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii
IVDMRKQRHAIVQTRNQYELVHRAVVDMFQ
. .|||| .||. .|. .. |. .|.
vnelrkqrismvqnldqfifiYeallfyfa
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 112-296 | 5.5e-18 | 59.8 | In-house | 43-227 (263) | alignment | ||
Range on Protein: 112-296
Range on HMM: 43-227/263.0
LPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEG-EEHCFGDILVTQIGQQRvtkDFMIRTLKATR----DKEEKIFNQFHYTAWPDHGVPT
| |...|.... .|| .|| |. | |. ||..|. | | . .. |. | | ...||. . |. . .... |. |... |.
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs...dvllktlellstlgeKkkthtvkhysykgWiekndpe
SVKPILDMIKLVREYQtaeepPIVVHCSAGCGRTGTICVIDYVRN--ALQLEKID-QNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
. || ..|..|. . ..|||||.| ||. |.. | ..|.. . .. .. ..|..|.. ..| | |.|..
lareilnilkvarnsk.....slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfv
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 78-293 | 1.2e-17 | 59.0 | In-house | 36-256 (290) | alignment | ||
Range on Protein: 78-293
Range on HMM: 36-256/290.0
LLSQIDNVEGSDYVNANFLKGAaNDHTYLAAQGPLPH-------TVNEFWRMLWECNTEIIVMACNEFELGRH----KCERYWVD-EGEEHCFGDILVTQ
| . . .||. ||... . |. .. | |. . |...|| | . . . .|| |. | .. |..| . .||| |... |
vLkgygkrfnddyiHAnrvtcp.nglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkC
iGQQRVTKDFMIRTLKATRDKEE-KIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaeepPIVVHCSAGCGRTGTICVIDYvrnALQLEK-IDQNFS
.. .|. .|.| . |.|| .. . | . |. . | .|..|. |. ..| |..||| | | .. |. . |. ....
.kskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvkaskt....pvivHcvdGiSrsAalaaiil...gyQkiaetsgsvk
LYDIIVDMRKQRHAIVQTRNQYELVHRAVV
| |.. ..|||| ... ... | ..|
ledvlkalrkqralaitsalelafvdagiv
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 62-151 | 2.4e-15 | 50.7 | In-house | 50-155 (349) | alignment | ||
Range on Protein: 62-151
Range on HMM: 50-155/349.0
RKNRYKDILPFDHSRYLLSQ--------------IDNVEGSDYVNANFLKGA--ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKC
|||||||||..||| | . | ||.|||.|| . . .. |.| | ||| ||..|.... . .... ...||. .||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
ERYWVD
..|| .
diywqe
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 192-297 | 4.9e-15 | 49.7 | In-house | 221-345 (349) | alignment | ||
Range on Protein: 192-297
Range on HMM: 221-345/349.0
NQFHYTAWPDHGV---PTS------VKP-ILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNAL-----QLEKIDQNFSLYDII----VDMR
|. . |.| .. | | ||. ..| ..|.. ....|||||||||||... .|.. . | . ||. . | |.| .|
lqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelr
KQRHAIVQTRNQYELVHRAVVDMFQ
||| ..|| .|. .. |.. |.
kqrismvqnlaqfiaiyealLkyfa
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 103-289 | 2.5e-14 | 47.9 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 103-289
Range on HMM: 5-197/199.0
HTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGEEHCFGDILVTQIG---QQRVTKDFMIRTLKATRDKEEKIFNQFHYTA
. |.|.| || .|. .||.|.|| . ||| .. || | .| . || . | .| | ..| . .. .|.
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPTS---VKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVH
| .. | | .. .. . |. . |..|||| | | || . .| . . | |... .|. | |. . ..|....
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 103-289 | 2.5e-14 | 47.9 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 103-289
Range on HMM: 4-196/198.0
HTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGEEHCFGDILVTQIG---QQRVTKDFMIRTLKATRDKEEKIFNQFHYTA
. |.|.| || .|. .||.|.|| . ||| .. || | .| . || . | .| | ..| . .. .|.
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPTS---VKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVH
| .. | | .. .. . |. . |..|||| | | || . .| . . | |... .|. | |. . ..|....
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 60-300 | 9.6e-13 | 42.2 | In-house | 51-289 (302) | alignment | ||
Range on Protein: 60-300
Range on HMM: 51-289/302.0
NMRKNRYKDILPFDHSRYLLsqidNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTV---NEFWRMLWECNTEIIVMACNEFELGRhKCERYWVDEGEE-
|..||. .|. |. . | . | .|||| .. .. . || | .. .||||| .. . .|.. | || . . .. . ..
nlkknqsedvpildsnlvkl....eaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdy
HCFGDILVTQ--IGQQRVTK-DFMIRTLKATRdKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNA
. .|.. | . . .. .| ..| | . . | . | |... ||... . .. | . .. . ..|. |.|| |.. . . .
keygkmfvNnrkVekaeeektryviEvlPegc.snsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavavek
LQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHL
|| . .. .|. .|.|| ..|.. .|| ...|.. .. ..
lqkg...kepnikeivksiRsqRpravdslkQyvslyialllyikkkv
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 194-290 | 2.6e-12 | 41.5 | In-house | 85-170 (182) | alignment | ||
Range on Protein: 194-290
Range on HMM: 85-170/182.0
FHYTAWPDHGVPtSVKPILDMIKLVReyQTAEEPPIVVHCSAGCGRTGTICVIdYVRNAlqlekidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHR
.. .|.|.||. |.. |||..|.| .. .| . ||| || |||| . |. | .... . | .|..| .|||.| |||.
vynfgwkDygva.sleriLdivkvva..falqegkvavhChaGlGrtGvliac.ylvya.......krltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 224-299 | 8.3e-12 | 39.4 | In-house | 245-317 (319) | alignment | ||
Range on Protein: 224-299
Range on HMM: 245-317/319.0
AEEPPIVVHCSAGCGRTGTICVIDYvrNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRaVVDMFQAH
. |.||||| | ||||.. | . .||. . . ... .|..| |.|..|||.... |. .. ..
esqGPlvvhcsdGvGrtGlviasdi..airsleeskrsvdiPqlvssvrrdrasavltkeqyefiyk.vlseyakk
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 192-292 | 2.8e-11 | 38.9 | In-house | 80-173 (194) | alignment | ||
Range on Protein: 192-292
Range on HMM: 80-173/194.0
NQFHYTAWPDHGVPTSVKPILDMIKLVREYQTA-EEPPIVVHCSAGCGRTGTICVIDYVRNalqlekidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHR
... .||.|.. | . .|. ..|| |. . .. ..||| || |||||... . ...|. . | .| | ........| ...
ieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyr........lgmsaeeAialfrekRpgaipnqdyleallk
AV
.
ry
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 50-110 | 1.6e-10 | 35.1 | In-house | 38-95 (95) | alignment | ||
Range on Protein: 50-110
Range on HMM: 38-95/95.0
YPTSAGESDVNMRKNRYKDILPFDHSRYLLSQidnVEGSDYVNANFLKGAANDHTYLAAQG
| ..| |. |. |||. .|.|.| .| |. |||.|| |. | | |.||||
apytvgsseanipknrflnifpydatrvvltt...krdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_eak_pd | Subfamily eak | 48-206 | 3.3e-09 | 30.6 | In-house | 40-196 (332) | alignment | ||
Range on Protein: 48-206
Range on HMM: 40-196/332.0
KVYPTSAGESDVNMRKNrYKDILPFDHSRYLL-SQIDNVEGsdYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCE
.. | .. ....| .|.|.|. | | | .| |.|| .. . . |. . . | ||.|. | .. ||. .. ||. | .
rllsisetarleavnrn.vvkivpydrylvrltssqlnrlG..yinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksd
RYWVDEG-EEHCFGDILVTQIGQqRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPT
.|. |.. || || . |.. . . | |. .. | . ... | . .|
kyfpdktreelkfGildverkef.vkrniletrllelskGnethrvlhykvfGwtettlpk
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 42-155 | 3.5e-09 | 30.6 | In-house | 16-128 (332) | alignment | ||
Range on Protein: 42-155
Range on HMM: 16-128/332.0
QRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEgsDYVNANFLKGAANDHTYLAAQGPLP-HTVNEFWRMLWECNTEIIVMACNEFEL
| . . || . . || || . ||||| |. | . |. ||... | .. .|. || |. || ||||. | . .|.. . |
qmhtsamtypntydkflnnmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidek
GRHKCERYWVDEGEE
..|. | | |
qkrkapydisdrgfe
|
|||||||||
PTEN_1 | 181-244 | 4.4e-09 | 31.4 | In-house | 82-148 (196) | alignment | |||
Range on Protein: 181-244
Range on HMM: 82-148/196.0
KATRDKEEKIFNQFH--YTAWPDHGVPTSVKpILDMIKLVREYQTAEE--PPIVVHCSAGCGRTGTIC
....|.|| . ... ..|||.|. . ..|..| . |. . . ..||| || ||.||..
grsydleeffksgveylhfpieDhgapslse.lfdicksfiewllsdpngnvVlVHCkaGlgRsGtvv
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 58-101 | 1.3e-08 | 28.7 | In-house | 37-79 (244) | alignment | ||
Range on Protein: 58-101
Range on HMM: 37-79/244.0
DVNMRKNRYKDILPFDHSRYLLSQIdNVEGSDYVNANFLKGAAN
.| |||| .|||||..| .|| . |||||.|||...|. |
sanatknryinilpfdetrvilsss.kkegsdyinanyiqgsqn
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 168-268 | 2.9e-08 | 28.9 | In-house | 55-155 (184) | alignment | ||
Range on Protein: 168-268
Range on HMM: 55-155/184.0
QQRVTKDFMIRTLKATRDKEEKIFN-QFHYTAWPDHgVPTSVKPILDMIKLVREYQTAEEPP-IVVHCSAGCGRTGTICViDYVRNALQLEKIDQNFSLY
... .....| |.. |. ..| |. . . . || | ... . .... .... ... .|||| || ||||.. | |. ..|.||| .. .|.
ekkhkdhykiynlrserkydskkfdgrvavypfdDh.nppplelleeivediekwleedkknvvvvHCkaGkGRtGvliv.ayllkslllekaeealelf
DII
. .
aea
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 230-295 | 3.3e-08 | 27.8 | In-house | 1-63 (69) | alignment | ||
Range on Protein: 230-295
Range on HMM: 1-63/69.0
VVHCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
|||||.| ||||| | .. ||. ... . ||| | .| |.| ..| |.|.
vvhcssGtGrtGtfiaimvemariksekl...vdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 229-295 | 4.5e-08 | 27.4 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 229-295
Range on HMM: 1-64/69.0
IVVHCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
.|||||.| |||||. | .. ||. ... . ||| | .| ..| ..| |.|.
mvvhcssgtgrtgtfiaimvemariksekl...vdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 56-127 | 1e-07 | 25.8 | In-house | 33-109 (347) | alignment | ||
Range on Protein: 56-127
Range on HMM: 33-109/347.0
ESDVNMRKNRYKDILPFDHSRYLLSQIDNVE-----GSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECN
| . .. ||| || | .| .|| . |.|| .| .. |. .| |||.|| .||.|. .
ewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 55-99 | 1.1e-07 | 25.6 | In-house | 42-86 (440) | alignment | ||
Range on Protein: 55-99
Range on HMM: 42-86/440.0
GESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGA
| ||||..|| .|||| .| .. | |||.|| ...|
aslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 115-301 | 1.8e-07 | 24.1 | In-house | 130-314 (346) | alignment | ||
Range on Protein: 115-301
Range on HMM: 130-314/346.0
TVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQ--QRVTKDFMIRTLKATrDKEEKIFNQFHYTAWPDHGVPTSVKPIL
|..|| |... . ... . . | . ..| . | ... . |.. | | . . | . |.. | | ||.
fvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytgkmfinnrradvsgdpkeytievlpeg.nsdsvicqvhhhapwkhlqqppktlpii
DMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQlEKIDQNfsLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQAHLG
||. . .. . | ||||. .. | | |. . |. | ...|. ....|| |.. || .. |.| . |
kmihqflsekqvqnagvcvvslfgcgracsfigalyainqln.ngiepn..iceimknikqqrpggvesfaqyasiyaivfdyiarkrg
|
|||||||||
subfamily_VSP_pd | Subfamily VSP | 170-245 | 2.1e-07 | 25.1 | In-house | 71-147 (212) | alignment | ||
Range on Protein: 170-245
Range on HMM: 71-147/212.0
RVTKDFMIRTLKATRDKEEKIFN-QFHYTAWPDHGVPTsVKPILDMIKLVREYQTAEEPPI-VVHCSAGCGRTGTICV
. .. . . | . |. .||.|| . . || ||. .. .| . | |.|. ... . ..|| | ||||||
khrdhykvvnlcseraydekyfnnrvkriliddhnvpk.leellvftkevkewlekdlknvlaihckGGkgrtGtivc
|
|||||||||
subfamily_DSP23_pd | Subfamily DSP23 | 200-290 | 4.1e-07 | 24.7 | In-house | 60-140 (148) | alignment | ||
Range on Protein: 200-290
Range on HMM: 60-140/148.0
PDHGvPTSVKPILDMIKLVREYQTAEEpPIVVHCSAGCGRTGTICVIDYVRNalqlekidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHR
.|. | ... . .....| | . .| . ||| | |||||. .|.. .... . | ..|..| |.| .| .||.
ddyh.ppaleqvvefvrvveeaeekne.avsvhcllgrgrtgtmlacylvke........rklaaaeaiaevrrlrpgsvetveqeklvrd
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 81-204 | 8.1e-07 | 23.4 | In-house | 6-126 (130) | alignment | ||
Range on Protein: 81-204
Range on HMM: 6-126/130.0
QIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACN-EFElgrhkcERYWVDEGE-EHCFGDILVTQIgQQRVTKDFMIR
... ..| .|.||.|. . || .| || | .||.|. | ...|. | | . || | | ||.|| .. |
evsrlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee......deywpdsePlewyeediivtlt.drdefknikas
TLKATRDKEE--KIFNQFHYTAWPDHGV
|. .| | . . |. . || |
nleiesdlneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_PTPMT1_pd | Subfamily PTPMT1 | 171-285 | 3.1e-06 | 21.7 | In-house | 53-158 (171) | alignment | ||
Range on Protein: 171-285
Range on HMM: 53-158/171.0
VTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEpPIVVHCSAGCGRTGTIcVIDYVRNAlqlekidQNFSLYDIIVD
..... ...| . .. .| .. . | .|. .... ... ......... . . ||| || ||..|. |. |. ...|. . .
lneeyelkalansteewkklgveqlqlatvDfteapdleklekgvefiekvaskgk.rvYvHCkaGrgRsatl.vacylmkk.......eklspeeAlka
MRKQRHAIVQTRNQY
..|.|. | ..|.
lkkkRkiirlakkqw
|
|||||||||
subfamily_eak_pd | Subfamily eak | 229-296 | 3.4e-06 | 20.7 | In-house | 239-305 (332) | alignment | ||
Range on Protein: 229-296
Range on HMM: 239-305/332.0
IVVHCSAGCGRTGTICVIDYVRNALQlEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF
.. .. | |.|. ||| . . .. .|. .|. |.|. ....| | . |. ... .|.| .
piiqsarGsaraGvfvvidllirlid.nkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 52-134 | 8e-06 | 18.9 | In-house | 19-74 (169) | alignment | ||
Range on Protein: 52-134
Range on HMM: 19-74/169.0
TSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNAnflkgaandhtylaaqgplphtvnefwRMLWECNTEIIVMA
| .| ||| | | | | .. . ||||.|| ||.|| |. .||.
nfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvl
|