Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRD_pd | Subfamily PTPRD | 1196-1526 | 3.8e-172 | 568.8 | In-house | 2-333 (564) | alignment | ||
Range on Protein: 1196-1526
Range on HMM: 2-333/564.0
HPPIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLL
..||||....||...|| |. . |..||..||.||||||...| ..||.||||||..|||||||.||..|| .|||| ||...|||||..|||||||||
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPla
ETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLA
||..|||||||||...||||.|||||...|||..|||....|.|| ..||| ...|||.|..|.| | |..|.|.|||.||.||.||||||||.|||.|.
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLd
FISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLT
.|..|...|.||||||||||||||||||..||||.||||||.|||||||..|..||.|||.||||||||||||||..||.|.|.|||...||. |.|||.
lirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkLa
ALEPGETITGMENEFKRLA-SQKAQPSRFVSA
|.....||.|.||.||| ... ....| .|
eveedtemtgleleFqrLatakeieleefava
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1199-1513 | 1.6e-131 | 433.1 | In-house | 2-318 (318) | alignment | ||
Range on Protein: 1199-1513
Range on HMM: 2-318/318.0
IPVSQFQEHIERLKGNDAMLFSQEYESIE-PGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
|.|.....|..||. . .|.|.||| .. ...|. .|. ..|| ||||||..||||.|| |...|| .|||| |||| ||||...||||.|.|| ||
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFI
. ||||||||| . .|||.|..||| ..|...||| .. ..|| ..|.| ...||..|..|.| . .. . |.|.|.|...|.|||.||||...|.|...
ieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlv
SRVKSCN-PPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLTA
.|.. . ...|||||||||||||||| .|..|..|||||.|..||... |. || ||| |||||.||.||...| ||.||| |||.|..| .|..|.
rqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelre
LEPGETITGMENEFKRL
.| | |. ||.||
qdpesgttemdaefqrl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1518-1771 | 3.4e-126 | 417.1 | In-house | 35-286 (564) | alignment | ||
Range on Protein: 1518-1771
Range on HMM: 35-286/564.0
AQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCH
| ... .|| |||| |||. || .|. .||.|....|.|||||||||.|||||.|.||||||||||||.||||||.|||||..||||.||.|.|..|||
gqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkch
QYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPISVHCSAGVGRTGVFI
.|||......|....|....|... .|..|.||...... .||..|||.||.||..|||.|.....|.| .|....| ..||| |||||||||||.||
kYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne..pdagPivVhCSaGVGRTGtfi
TLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFDH
.....|||...|. ||..|.||.||.||.||||||.||.|...| ||.| ...
vidamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1198-1511 | 2.5e-121 | 399.6 | In-house | 4-319 (319) | alignment | ||
Range on Protein: 1198-1511
Range on HMM: 4-319/319.0
PIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
.|.| ...|....|. . .|. .|.. .. ....|.|... | ||.|||| |..|||..||.||...| .|||| ||.. |||......||||.|| .|
eievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlent
MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALV-KNRSMEKREVKQFQFTAWPDHGVPEHATSVLAF
. ||||||||... ..||.||| |. .||. .|||. . |.|| . |||.. ||. | .| . | |. .| ||||.||.|.||||.|||.|||.|..
iedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldl
ISRVK-SCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLT
. |.. | . ...|||||||||||||||..||.| ||||.|.| ..|.. | ||.||| |||..|||.||.||| ||| .| ||.. ..| ...|.
lkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqla
ALEPGETITGMENEFK
... ||.|.||.
ekvadtgetglerefq
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1199-1487 | 2.6e-116 | 384.1 | In-house | 1-299 (563) | alignment | ||
Range on Protein: 1199-1487
Range on HMM: 1-299/563.0
IPVSQFQEHIERLKGNDAMLFSQEYESIE---PGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGS-DYTNANYCDGYRKQNAYIATQGPL
.||..|..|. |. .. . ||.|.|... .... .||. . || |||| |..|||.||| |||. | .. || |||| |||.|..|.|||||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgpl
LETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVK----NRSM--EKREVKQFQFTAWPDHGVPE
.|. |||||.|||....|||.|.|.||.| |||.|||. . |.|| .|||| .. ||.||||.. . . . . ....|.|...| ||||||||
kdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPe
HATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNL
|.. || |. . . |. .|||||||||||||||| |||.|..|..|..|..|...| . .|||||..|||||||||.|.|| ||.||. ||. | ..
hslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqv
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1504-1772 | 1.9e-114 | 377.0 | In-house | 20-286 (318) | alignment | ||
Range on Protein: 1504-1772
Range on HMM: 20-286/318.0
TGMENEFKRLASQKAQPSRFVSaNIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
. ...|..||. ........ | . |.||.||| || .|. || ||.. |.||||||||..|||||...||||.|.||.|| ||||||.|||||..||
lllseeyerlsrseetvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsaviv
MLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqEGPIS
||....| |..|.|.||| . | |. ||. ..| .. .|.||||||| .||..||...|.||..|||.|| ...|...||.|.... | .|||
mltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksg.agpiv
VHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFDHY
||||||||||||||.....|||.. |..||.|||||.||.||..||||||||.|.|.. ||.| |.| .
vhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdte
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1193-1510 | 2.5e-111 | 366.7 | In-house | 8-330 (330) | alignment | ||
Range on Protein: 1193-1510
Range on HMM: 8-330/330.0
MMSHPPIPVSQFQEHIERLKGNDAMLFSQEYESIEP-GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQ
..|.|| ...| |.. . .|. || .|.... | | . .. | || |||. |.. ||.||||||..|| . ||| || . |||.... .||.|
nkkyfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaq
GPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVK----NRSMEKREVKQFQFTAWPDHGVP
||. ||. |||||.|||.. ||||.|.|.||.. || ||||. || |.|.. |.|.| |||| | . . | ..| |.|| ||.||| |||
GPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvP
EHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNL
.. .| .. .||..|. ||||||||||||||||..||.|..|||.| |. ||... | ||.|| ||||.||| ||...| | | ||... |
fepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvssl
YGHIQKLTALEPGETITGMENEF
|.||| . .| . .|.|.||
ekhlqklynkitgtdkigleeef
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1196-1511 | 7.4e-107 | 351.8 | In-house | 1-313 (314) | alignment | ||
Range on Protein: 1196-1511
Range on HMM: 1-313/314.0
HPPIPVSQFQEHIERLKGNDAMLFSQEYESIEPGqqftWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLL
|| | | ..| || ... | .||||. | || .. . |. |||. ...|||.|||.| ...| | ||| ||.. |.|.. .|.|.|||||
hpairvadllqsiallkraegygfkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlq
ETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEkYGFIQVTLLDTTELATYTVRSFALVK--NRSMEKREVKQFQFTAWPDHGVPEHATSV
||..||||.|..... .|||.|.| | |||| .||| . || |.|.|..|. || . || |.. | |.|||.||||..||||.|| .||..
etvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgl
LAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQK
|... |||. ....||.|||||||| ||||..|.||..|. |..|..||.. | ||... ||.|||||.||.... ||. | | . . .. .
lklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalyle
LTALEPGETITGMENEFK
. |.| . ...||.
sirldpqtnssqlkeefq
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1203-1482 | 3.6e-106 | 349.8 | In-house | 13-297 (298) | alignment | ||
Range on Protein: 1203-1482
Range on HMM: 13-297/298.0
QFQEHIERLKGNDAMLFSQEYESIEPGQQ----FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETM
..|. . | .. . ...|.. .. ... .... .. ..|| |||||..||.|.|||.|. ... ||| || . ..|...||.||||.|| ||.
alqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetv
ADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFIS
.||||||.|. .||||.|.||| ...|. .|||.. .|.|| |.|.|| . | | ..|| ... |... ..|||.|..|| |||.||||.|||||....
edFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllr
RVKScNPPDAG--PIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEV
.|. .. .|| |..|.|||||||.|..|.|||.|||.|.|..||.. | ||..| .|||||||.||.|| ||..|. .|.
kvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1196-1474 | 4.6e-106 | 349.7 | In-house | 2-285 (288) | alignment | ||
Range on Protein: 1196-1474
Range on HMM: 2-285/288.0
HPPIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQ-QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPL
. .|.|... .....|. |. ... .|.| . . . ..|. ...|. |..|||| ....||||||.||...| .|||| ||.| |||......|||||||
dteisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPl
LETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKN----RSMEKREVKQFQFTAWPDHGVPEHA
.|..|||||||||....|||.|||.|..|.||.||||... ..|| |.||||....|..|||| . .... . |.|.|..|..|.|||||||...
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdsp
TSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
...|.|. .|....... ||.||||||||||||..|..| .||....|..||... | || ||..||||.|||.|..|||.|.
ellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1197-1478 | 3e-105 | 346.5 | In-house | 5-288 (293) | alignment | ||
Range on Protein: 1197-1478
Range on HMM: 5-288/293.0
PPIPVSQFQEHIERLKGNDAMLFSQEYESIEP-GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLL
|| ...|.||....| .. . ||.|||... |.. . . ..|..|. |||| |...|||||| |..... .|||| |||| .||. .. .|||||||
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlp
ETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTR-DQEKYGFIQVTLLDTTELATYTVRSFALVKnrSMEKREVKQFQFTAWPDHGVPEHATSVL
||. ||||||||.....|||.|.| |. .|||..|||. .. || |.|||. ..|| ...|.... | ..|.|.|.|..||.||||||||.....|
etvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktll
AFISRVKSCN--PPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASG
.|. .|.. ...||||||||||||||..| .| .|..|..| .|||.| |. || .||..||||.||||||... . . ..
dfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1203-1513 | 3.2e-105 | 347.1 | In-house | 4-314 (317) | alignment | ||
Range on Protein: 1203-1513
Range on HMM: 4-314/317.0
QFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFW
.. .....|. .|......|.| . . |.....|. ||.|||| ... ||||||.|||..| ..||| ||.| ||.......||||||| .|..|||
dlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFw
RMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKS
||||||....|||.|.|||..|.||.||||... .|| ..||||...||| .|.| . ...... |.|.|..|..|.|||||||.. ...|.|...|..
rmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavre
CNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLTALEPGET
..... ||..|||||||||||..|... |||....|..||.. | ||.||...|||.|||.|...||.| . . | . | .|. ...||.. ...
aledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllklliplaldd
ITGMENEFKRL
...| |.|.|
vklkekelkll
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1187-1477 | 3.8e-103 | 340.3 | In-house | 14-301 (308) | alignment | ||
Range on Protein: 1187-1477
Range on HMM: 14-301/308.0
SENGTAMMSHPPIPVSQFQEHIERlkGNDAMLFSQEYESIEPGQQ-FTWDHSNLETNKPKNRYANVIAYDHSRVILspmeGlPGSDYTNANYCDGY--RK
. . ..|. ...| .. ...|. .| |...|.| . . .......|. ||.|||| ....||||||.| . .|||| ||.| ||| ..
frdtsilvsslklsvldllkllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgysskl
QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTR---DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTA
....||||||| .|..|||||||||....|||.|||.|..|.||.||||. . ..|| ..||||....|..|||| . |..... | |.|..|..|.
prkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytn
WPDHGVPEHATSVLAFISRVKSCNPPdaGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVAS
|||||||......|.|. .|....|. |||||||||||||||..|..| .||....|..||... | || ||..||||.|||.|...||.| . .
WpdhgvPpspeilldflelvrkslpg..gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1479-1766 | 1.2e-102 | 338.5 | In-house | 2-286 (288) | alignment | ||
Range on Protein: 1479-1766
Range on HMM: 2-286/288.0
TTEVHARNLYGHIQKLTalepGETITGMENEFKRLASQKAQpSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIA
.||.....|. ...||. .||...||..| |.... . .|. |.|. ||| .| ||. .||.|... |||||||||||.||||.. ...||
dteisveellklvlkll....angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIa
TQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDA----RDGQSRTIRQFQFTDWPEQG
||||| .|.||||||.||||...|||| || |.|||||.|||| . | | ..| .||. .. |..|...||. ||.|||...|..|.||..|
tqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhg
VPKSGEGFIDFIGQVHKTKEqfGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|| | | ..||. .|.| . ..||. |||||||||||.||.| ..||....|| ||....||.||.||| ||||..||.|.|.|.||||
vpdspellldflrlvrkala..sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1495-1769 | 3.2e-102 | 337.2 | In-house | 33-302 (308) | alignment | ||
Range on Protein: 1495-1769
Range on HMM: 33-302/308.0
TALEPGETITGMENEFKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLqpirGvEGSDYINASHIDGY--RQRNAYIATQGPLAETTEDFWR
.||. ....| ||..| |.| . . .|. |.|| ||| .| ||. .||.| . |||||||||..||| ......||||||| .|.|||||
kllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwr
MLWEQNSTIIVMLSKLREMGREKCHQYWPAE---RSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQV
|.||||...|||| || |.|||||.|||| | | .| .|.| .||.... |..|....|. .||.|||...|..|.||..||| | | ..||. .|
mvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelv
HKTKeqfgQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSF
.|. ..||| |||||||||||.||.| ..||....|| ||.|..||.||.||| ||||..||.|.|.|.|||| ..
rksl....pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1504-1770 | 3.9e-101 | 333.3 | In-house | 23-287 (319) | alignment | ||
Range on Protein: 1504-1770
Range on HMM: 23-287/319.0
TGMENEFKRLASQKAQpsRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
|..|.||| | ... | ||. . || ||| || .|. || |... |||||||||||.||||..|...||||.||..|.||||||.||..| |.|
tllekefkllkeavnd..tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivv
MLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQ-SRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFgQEGPI
||.|| | .. |...||| | .| ..|.. .| .. .|| |..|. . . .|.. .||.|.||...||... . .|......|..|. |.|||
mltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrekt.qsgPi
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFD
||||||||||| ||.|...|||.. ||..|.|.||..|||||. |||...||.|.|.| ||.. ..|
vvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1478-1772 | 3.9e-98 | 323.4 | In-house | 1-296 (298) | alignment | ||
Range on Protein: 1478-1772
Range on HMM: 1-296/298.0
GTTEVHARNLYGHIQKLTALEPGETITGMENEFKRLASQKA--QPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNA
| ||..|..| ..|||.| .. ...||...||.|| | . . |. |.|| ||| .| ... || |. . . | |||||||....|..|||
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrna
YIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV
.||||.|| ||.||||||..|.... |||| .|.|... |.|.||| |....| . |. .|.... ..| |..||.... ..|..||..|| ||..||
fiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgv
PKSGEGFIDFIGQVHKTKEQFGQeGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFDHY
|. . .|.. .|.....| |. |. |.|||||||.| || .. ||||.. | ||.||.||.||..||..||||.|| |.|.| ||.| ||. .
penatsvldllrkvrasqqqagn.kpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnde
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1505-1769 | 9.6e-98 | 322.3 | In-house | 1-277 (284) | alignment | ||
Range on Protein: 1505-1769
Range on HMM: 1-277/284.0
GMENEFKRLASQKAQPS-RFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGV-EGSDYINASHIDGY-----RQRNAYIATQGPLAETTEDFWRMLWEQ
|.| ||..| |.. .. . |. |.|. ||| .| ||. .||.|... | |.|||||||..||| ......||||||| .|.||||||.|||
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
NSTIIVMLSKLREMGREKCHQYWPAER-SARYQYFVVDPMSEYNMPQYILREFKVTDAR-DGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ
|...|||| .| |.|||||.|||| | . .| | | .||.... |..|....|. .|.|||...|..|.||..||| | | ...|. .|.. |.
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen
FGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEG---IVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSF
....||| |||||||||||.||.| ..||....|| ||....||.||.||| ||||..||.|.|.|.|||| ..
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1198-1495 | 1.3e-97 | 321.6 | In-house | 3-303 (305) | alignment | ||
Range on Protein: 1198-1495
Range on HMM: 3-303/305.0
PIPVSQFQEHIERLKGNDAMLFSQEYESIEPGqQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
.| .......|. . ... . ..|.|. . . | . |.|| |||..... .|..|.||.. | |. ||| ||.| |||.....||..|||| .|
iialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlknt
MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQE--KYGFIQVTLLDTTELATYTVRSFALVK-NRSMEKREVKQFQFTAWPDHGVPEHATSVL
.|||||...| ...||||.||| | .. || ||||.. .| ..| ..|.| .... . |. | . . . . . |.| | |.|.| |||||||. |||.|
vadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsll
AFISRVKSCNPPDAG-PIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQK
.| ||. | | |..|||||||||||..|..| .|||.|.|..||... . || .| .|||| .|| |.|.|| | . .| |.. || ...|
slikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvnk
LT
|
lk
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1198-1473 | 1.4e-97 | 321.8 | In-house | 1-275 (278) | alignment | ||
Range on Protein: 1198-1473
Range on HMM: 1-275/278.0
PIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
||.|.........|. |. |...|.|.. . .|.....|. ||.|||| ....||||||.||...| ..||| ||.| |||......||||||| ||
pisvkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpet
MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPtRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFI
..||||||||....||||.|.|.|..||||.|||| .. ..|| ..||||....|..|||| . ...... |.|.| ......||||||||. ...| |.
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldfl
SRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
.|....... ||..|||||||||||..|... .||....|..||.. | || || .|||..||.|..|||.|
kavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1504-1766 | 5.5e-97 | 320.1 | In-house | 18-276 (317) | alignment | ||
Range on Protein: 1504-1766
Range on HMM: 18-276/317.0
TGMENEFKRLASQKAQpsRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
|....||..| |.| . |. |.|| ||| .| ||. .||.|.|. |...|||||||..||.......||||||| .|.||||||.|||..|.||
talleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtviv
MLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPIS
|| .| |.|||||.|||| . . | |.| .||. .. ..||...|.| .|..|||...|..|.||..|||.| . ..||. .|.. | ...||.
mLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvl
VHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|||||||||||.||.. ..||....|| ||....||.|| ||| .|||..||.|.| |.||||
VHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1221-1478 | 1.2e-96 | 318.7 | In-house | 4-277 (284) | alignment | ||
Range on Protein: 1221-1478
Range on HMM: 4-277/284.0
QEYESIEPGQQF---TWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGL-PGSDYTNANYCDGY-----RKQNAYIATQGPLLETMADFWRMVWEQRTN
.|.| . . . ......|. |. |||| ....||||||.|....| ..||| ||.| ||| ......||||||| .|..|||||||||...
eefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvr
TIVMMTKLEERNRVKCDQYWPTRD-QEKYGFIQVTLLDTTELATYTVRSFALVKNR-SMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNP--PD
.|||.|.|.|..|.||.||||. . .|| ..||||.... .|||| . |... . | |.|..|..|.|||||||......|.|. |..... |.
vIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpg
AGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK---TVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASG
|||||||||||||||..|..| .||....|. .||... | || ||..||||.|||.|..|||.|.. ..
ggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1212-1486 | 3.5e-96 | 317.3 | In-house | 8-288 (297) | alignment | ||
Range on Protein: 1212-1486
Range on HMM: 8-288/297.0
KGNDAMLFSQEYESIEPGQ-QFTWDHSNLETNKPKNRYANVIAYDHSRVILspmEGlPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRT
| .. .|...|.|.. | . ........|. |..|||| ....|||.||.| .. .|||| ||.| |||. ....||||||| .|..|||||||||..
kllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl...dd.egsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnv
NTIVMMTKLEERNRVKCDQYWPTR--DQEKYGFIQVTLLDTTE--LATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPP
..|||.|.|.|..|.||.||||. . .|| ..||||.... |..||.| . ...... |.|.|..|..| ||||||||...|.|.|| .|.....
tvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkl
--DAGPIVVHCSAGVGRTGAYIVIDSMLERIK---HEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARN
. ||..|||||||||.|..|..| ||.... .|..|||. | || ||. .|||.|||.|..|||.| . ...| . ...
lpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1502-1766 | 7.3e-96 | 316.1 | In-house | 10-272 (273) | alignment | ||
Range on Protein: 1502-1766
Range on HMM: 10-272/273.0
TITGMENEFKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLqpirGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTI
.|... ||..| |.| . . |. |.|| ||| .| ||. .||.| | .||||||||..|||.. ...||||||| .|.||||||.||||...
gltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrv
IVMLSKLREMGREKCHQYWPAER---SARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQ
|||| .| |.|||||.|||| | | .| | | .||.. . |..|....|. .|.|||...|..|.||..||| | | ...|| .|.|. |.. .
iVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealps
EGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
.||. |||||||||||.||.| ..|.....|| ||....||.||.||| ||||..||.|.|.|.||||
ngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1241-1477 | 8.8e-96 | 314.9 | In-house | 8-244 (250) | alignment | ||
Range on Protein: 1241-1477
Range on HMM: 8-244/250.0
TNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVkCDQYWPTRDQEKYG
|| |||||..||.|.|||.| . .| ||| || . .||....|.||||||| .|. ||||||.|. ..||||.|.|.| ... . ||||. ||||
qnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyG
FIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPP-DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK
..|.||.. | | ||.| . | |.. ..| |.|..|..||| ||||.||.||.....|.. .. ...|..|.|||||||.||.|.||..|||.|.||
dvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkek
TVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVAS
.||.. . ||..| .|...|||.|..|.. .|. |
vvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1507-1765 | 1.3e-95 | 315.1 | In-house | 35-294 (330) | alignment | ||
Range on Protein: 1507-1765
Range on HMM: 35-294/330.0
ENEFKRLASQKAQpSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLS
.||. | . . | . . |. || |||..|| ||. .|| |....||| |||||||.||||.... .||.|||..|| ||||||.|||.|. ||||.
reefnalPagpiq.atlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmlt
KLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDA----RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQegPI
.|.| .|||.|||| | . | | | . .| .|.| |.. |. .|| .||| || ||. ||| . | .... .|.|...| .. ||
elkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag..pi
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||||||||| ||.|. ||||.. |..||.|..|| ||.||| ||||. ||.|.|.. |||
vvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1206-1475 | 6e-95 | 312.6 | In-house | 10-279 (288) | alignment | ||
Range on Protein: 1206-1475
Range on HMM: 10-279/288.0
EHIERLKGNDAMLFSQEYESI-EPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRM
... . . .. ||.||.|. . ... . . ..| |..|||| |...||. || | .| .|.|| ||.| ||..|...|||||||| .|. |||..
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWel
VWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ-EKYGFIQVTLLDTTELATYTVRSFALVknRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC
|.|..|.||||.|.| |... ||..|||. |. ..|| ..|||... || ...|.. |. ......|..|.|..||||||||| .. .|.... ||
vyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkva
NPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
|. |.|||.||||||||||| .|..| .......|...|. | |. || ||. .|||..||.||.|.| . .
nqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1192-1476 | 8.4e-95 | 312.9 | In-house | 7-290 (297) | alignment | ||
Range on Protein: 1192-1476
Range on HMM: 7-290/297.0
AMMSHPPIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQfTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGL-PGSDYTNANYCDGYRK-QNAYIA
|.....|||.| . .. ..| |. .|. .|.|.. . . ...|. ||.|||| ....||||||.|.|..| ..||| ||.| |||.. ....||
allesipiplsvldlllllekansktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIa
TQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRvKCDQYWPTRDQeKYGFIQVTLLDTTELATYTVRSFALVKnrSMEKREVKQFQFTAWPDHGVPEH
||||| ||..|||||||||....|||.|||.|..| ||.||||.. . .|| ..||||....|. |||| . ... . | |.|..||.| |||||||..
tqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvpps
ATSVLAFISRVKSCNP--PDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVA
....| |. |.... |. ||..|||||||||||..|... |||....|..||.. | || ||...|||..||.|...||.| .
lellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1502-1769 | 9e-95 | 312.6 | In-house | 11-280 (297) | alignment | ||
Range on Protein: 1502-1769
Range on HMM: 11-280/297.0
TITGMENEFKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLqpirGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTI
..... ||..| . .. . . |. |.|. ||| .| ||. .||.| . |||||||||..|||.. ...||||||| .|.||||||.||||.|.
flalllkefeellplll.lgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtv
IVMLSKLREMGREKCHQYWPAE--RSARYQYFVVDPMSEYN--MPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFG
||||..| |.|||||.|||| | | | |.| .|.. . |.||...||| ..|.|||...|..|.||. ||| | . ..||| .|.| ...
Ivmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllp
QEGPISVHCSAGVGRTGVFITLSVVLERMR---YEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSF
..||. |||||||||.|.||.. ..|.... .|| ||....||.||.||| .|||..||.|.|.| ||.| ..
sggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1496-1769 | 1.9e-94 | 311.7 | In-house | 24-292 (297) | alignment | ||
Range on Protein: 1496-1769
Range on HMM: 24-292/297.0
ALEPGETITGMENEFKRLASQKAQpsrFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGV-EGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRM
||. .|....||..| |.| .. |. |.|| ||| .| ||. .||.|.|..|| ..|||||||..|||.. ...||||||| ||.||||||
llekansktllllefeellslkpd...ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrm
LWEQNSTIIVMLSKLREMGReKCHQYWPAERSaRYQYFVVDPMSEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTK
.|||..|.|||| || |.|| ||.|||| | . .| |.| .... . |..|...||. .|.|||...||.|.||. ||| | | ...|. .|..
vweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvreal
EQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSF
.. ...||. |||||||||||.||.. .||....|| ||....||.|| ||| .|||..||.|.|.|.||.| .
aelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1195-1474 | 4.8e-94 | 310.8 | In-house | 5-303 (307) | alignment | ||
Range on Protein: 1195-1474
Range on HMM: 5-303/307.0
SHPPIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQF---TWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGL-PGSDYTNANYC--------DGYR
...|.. .. .. .|. .. ... .|.|.. . . | ......|. ||.|||| ....|||.||.||...| ..||| ||.| |||.
lslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgyd
KQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQE-KYGFIQVTLLDTTELATYTVRSFALVKN-RSMEKREVKQFQFTA
.....||||||| ||..|||||.|||....|||.|.|.|..|.||.||||. ..| || ..||||....|. |||| . . . . | |.|..|..|.
lkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytg
WPDHGVPEHATSVLAFISRVKSCNPP--DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKT---VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
|||||||.. ..|.|| .|.... . ||..|||||||||||..|... ||.....|.| ||.. | ||.|| .||..|||.|..|||.|
wpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1490-1766 | 7.9e-94 | 310.1 | In-house | 13-304 (307) | alignment | ||
Range on Protein: 1490-1766
Range on HMM: 13-304/307.0
HIQKLTALEPGETITGMENEFKRLASQKAQ-PSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGV-EGSDYINASHI--------DGYRQRNAYIAT
.. .| .|.. . .||.. ||..| |.. . . . .|. |.|| ||| .| ||. .||.|... | |.|||||||.. |||.. ...|||
kllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIat
QGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSA-RYQYFVVDPMSEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPK
|||| || ||||||||||..|.||||..| |.|||||.|||| |.. | |.| .||. .. |..| ..||| .|.|||...|..|.||..|||.
qgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvpp
SGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
| | ..||| .|.| |. ...||. |||||||||||.||.. ..|.....||. ||....||.|| ||| .||...||.|.|.|.||.|
sfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1212-1474 | 1.2e-93 | 308.8 | In-house | 7-271 (273) | alignment | ||
Range on Protein: 1212-1474
Range on HMM: 7-271/273.0
KGNDAMLFSQEYESIEPGQ-QFTWDHSNLETNKPKNRYANVIAYDHSRVILspmeGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRT
| .. |. .|.| . . . ..|. ...|. || |||| ....||||||.| | .|||| ||.| |||......||||||| .|..|||||||||..
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnv
NTIVMMTKLEERNRVKCDQYWPTRD---QEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPP-
..|||.|.|.|..|.||.||||. ..|| ..||||.... ..|||| . |... . |.|.|..|..| |||||||.. .|.| || |....
rviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkaleal
-DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
. ||.||||||||||||..|..| .|.....|..||.. | || || .||||.|||.|..|||.|
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1503-1766 | 1.2e-93 | 308.9 | In-house | 19-277 (278) | alignment | ||
Range on Protein: 1503-1766
Range on HMM: 19-277/278.0
ITGMENEFKRLASQKAqpSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTII
|....||..| |.| . |. |.|| ||| .| ||. .||.|... |...|||||||..|||.. ...||||||| ||.||||||.||...|.|
ktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtti
VMLSKLREMGREKCHQYWPaERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPI
||| .| |.||.||.|||| . | .| |.| ..|. .. |..| ..||. .||.|||........||..||| | . ..||. .|.. | ..||.
vmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale..dsngpv
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|||||||||||.||.| ..||....|| ||....||.||.||| .|||..||.|.|.|.||||
lVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
DSPc_SM00195 | 1506-1766 | 1.1e-91 | 302.2 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 1506-1766
Range on HMM: 2-262/263.0
MENEFKRLASQKAQPsRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
...||..| ... . .. .|....|| ||| || ||. .|| |... . ||||||||..|.|......|||||||| .| |||||| ||....|||||
lkeefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
SKLREMGREKCHQYWPAE--RSARYQYFVVDPMSEYNMP-QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFgqEGPI
.. | |.|||..||| | .. ..... | ... ... ..|||....| . ..|...|.|...||..|||.| . ..... .|.|.|.. .|||
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpi
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|||||||||||.|.|....|.... | ||.|..||.||.||| ||||..||.|.|.|.|||.
vVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 1506-1766 | 1.1e-91 | 302.2 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 1506-1766
Range on HMM: 2-262/263.0
MENEFKRLASQKAQPsRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
...||..| ... . .. .|....|| ||| || ||. .|| |... . ||||||||..|.|......|||||||| .| |||||| ||....|||||
lkeefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
SKLREMGREKCHQYWPAE--RSARYQYFVVDPMSEYNMP-QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFgqEGPI
.. | |.|||..||| | .. ..... | ... ... ..|||....| . ..|...|.|...||..|||.| . ..... .|.|.|.. .|||
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpi
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|||||||||||.|.|....|.... | ||.|..||.||.||| ||||..||.|.|.|.|||.
vVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1197-1495 | 2.7e-91 | 300.9 | In-house | 2-306 (307) | alignment | ||
Range on Protein: 1197-1495
Range on HMM: 2-306/307.0
PPIPVSQFQEHIERLKGNDAMLFSQEYESIE-PGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLL
..|.. . .| .. |.. ... .|||..| . . |. . |. |||| ...|.|. ||.|....| ||| ||.. ||.... .|| |.|.
gaiaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPve
ETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNR--S---MEKREVKQFQFTAWPDHGVPEHA
.|. |||||..|| ..|||...|.| || ||..||| |. .|| | |.| .. . |. |.. . |. | ..|.| |...|.|.| |||.|
atigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPeva
TSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGH
...| .|..|.. . . .||||||||||||.| .. .||.|...| |..|||. | || ||| .|| |||.|.. || . | |.. ..| .
rgllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddleda
IQKLT
|..|
ierlc
|
|||||||||
DSPc_SM00195 | 1219-1474 | 7.7e-91 | 299.4 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 1219-1474
Range on HMM: 2-261/263.0
FSQEYESIEPGQ-QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMT
...|.|..| . . . .... . || |||| |.. |||.||.|.. |. .|||| |||| .|..|...|||||||| .|..||||||||.....|||.|
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
KLEERNRVKCDQYWPTR--DQEKYGFIQVTLLDTTELA-TYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVH
. ||... |||.||| ..|..| |.|.| .... ...| . | |. |.|.|.|.|...|||||||....|||.... ||... ||||||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
|||||||||....||..|.....||.||| |. || || ||||.|||.||.||. |.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 1219-1474 | 7.7e-91 | 299.4 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 1219-1474
Range on HMM: 2-261/263.0
FSQEYESIEPGQ-QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMT
...|.|..| . . . .... . || |||| |.. |||.||.|.. |. .|||| |||| .|..|...|||||||| .|..||||||||.....|||.|
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
KLEERNRVKCDQYWPTR--DQEKYGFIQVTLLDTTELA-TYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVH
. ||... |||.||| ..|..| |.|.| .... ...| . | |. |.|.|.|.|...|||||||....|||.... ||... ||||||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
|||||||||....||..|.....||.||| |. || || ||||.|||.||.||. |.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1195-1500 | 2e-90 | 298.0 | In-house | 2-304 (315) | alignment | ||
Range on Protein: 1195-1500
Range on HMM: 2-304/315.0
SHPPIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPL
.| |||. |. .. . | . | |.|||| || . | .. || |||| |.||||.||| | .| |.||| |||. ||| |.. |||.|||.
ahqpipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpn
LETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRdQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMekREVKQFQFTAWPDHGVPEHATSVL
... ||||.|.|. .|||.|.| |... |...||| . . || | ||. . ||||... | . . ||| |...|.||| |||.......
vasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvvfgdni..revvqlhytswpdmgvpkytiplm
AFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVhARNLYGHI-QK
.| .|| . ..|.|||||||||||||..| .|..|.... |. .|.| .| .|..| |||. ||| ||..|| |.. | | . |..|| . .
nlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsi.aqdlylqryds
LTALEPG
| | |
llapspd
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1525-1766 | 2.1e-89 | 294.6 | In-house | 5-246 (249) | alignment | ||
Range on Protein: 1525-1766
Range on HMM: 5-246/249.0
SANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAER
|. |.|| ||| .| ||. .||.|....|...|||||||.||||.. ...||||||| ||.|||||||||...|.||||..| |.|||||.|||| .
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplgg
SARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLE
| | |.| .|.. .. |..|....|. ||.|||....|.||||..|||.| | ..||| .|.| |. ...||. |||||||||||.||.. .||
sleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmle
RMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
....|. ||....||.||.||| .||...||.|.| |.||.|
qlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1196-1494 | 1.1e-88 | 292.6 | In-house | 13-310 (319) | alignment | ||
Range on Protein: 1196-1494
Range on HMM: 13-310/319.0
HPPIPVSQFQEHIERLKGNDAMLFSQEYESI--EPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGP
|..|. . | . . .| . |. . . . . ...||. || |||. |..|.|...| | ...| .||| || . .||.... |||.|||
vpdfpayyqqlsnksdfdddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGP
LLETMADFWRMVWEQRTNTIVMMTkleernRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVK-NRSMEKREVKQFQFTAWPDHGVPEHATS
| .|.||||||.||... |||..| . || |||| . ..|.. .| . .| | |.||.. | . . ..|...|| | |||.|||....
ldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsd
VLAFISRVKSCNPP--DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGH
.. .. .|. . . .|||||||||||||.|||.| .|.|.|.|| ||.| | || ||| .|| || ||. || | | ..| .. .
lmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpay
IQKL
...|
leel
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1205-1476 | 1.1e-88 | 292.0 | In-house | 3-277 (281) | alignment | ||
Range on Protein: 1205-1476
Range on HMM: 3-277/281.0
QEHIERLKGNDAMLFSQEYESIEP-GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWR
..|...|. || | .|||... |.. | |. . |. |||| |..|||..|| ..| | .|| |||...||.....|||||||. .....||.
rkhlkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWq
MVWEQRTNTIVMMTKLEERNRVKCDQYWPTRD-QEKYGFIQVTLLDTTELATYTVRSFALvKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKS
|||||. ..|||.|. | ...|| .||| . . ||| ..|. . ..| ||| | | | ...| |.|||.|...|||||||||. .. .| | . |..
mvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlk
CNPPDA-GPIVVHCSAGVGRTGAYIVIDSMLERIKHE-KTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVA
.. .. |.|.||||||||||.|| .| .......| ...|. |. || .||.|||| || |.. |. .|.
ltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1233-1474 | 1.1e-87 | 289.0 | In-house | 2-245 (249) | alignment | ||
Range on Protein: 1233-1474
Range on HMM: 2-245/249.0
TWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP
......|. ||.|||| ....||||||.||...||..||| ||.| |||. ....||||||| ||..|||||.||.. ..|||.|.|.|..|.||.||||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
TRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNP--PDAGPIVVHCSAGVGRTGAYIVIDS
... .|| ..||||...... |||| . |... |.|.|...|.| |||||||.. ..|.|| .|.... |. ||..|||||||||||..|...
lggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
MLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
|||....|..||.. | || ||...||..|||.|..|||.|
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1480-1766 | 2.3e-87 | 287.8 | In-house | 5-285 (293) | alignment | ||
Range on Protein: 1480-1766
Range on HMM: 5-285/293.0
TEVHARNLYGHIQKLTAlepgETITGMENEFKRLASQKAQpSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIAT
........ .|..|..| .. ... .|...| . . . ..|. ..|. ||| || ||. .|| |..... .|||||||..|.||.... .|||
kpiklekfeehvkkmka....dsdlrfseeyeelkavgkd.qavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiat
QGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAE-RSARYQYFVVDPMSEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKS
|||| ||..|||||.||..|.||||| .| | |..||..||||. .. | |. ..| .. ....||.|.. . ..|..||..|| ||. |||..
qGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPek
GEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
. ..||. .|....|. ...|| |||||||||||.||.| .|.... | .||.| .| ||..| .||||.|| | ... |..|
tktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldll
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1198-1512 | 2.8e-87 | 287.5 | In-house | 2-314 (315) | alignment | ||
Range on Protein: 1198-1512
Range on HMM: 2-314/315.0
PIPVSQFQEHIErlKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
||||.|| .. | . |||.|. . . . . . | .|||| |.. .|..||.| .. | ||| || | .. ...||||.|||| .
pipvaqfpafvn..knrhtalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkas
MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPT--RDQEKYGFIQVTLLDTTELATYTVRSFalVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLA
. ||||||..... ||||.||..| ...|| |||| | ..| |.|.||.. . ..| . | .| |.| | ||||| |||.||.....|.|
vddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl..vtrkseesrtvtqfqftewPdkGvdkqtssllk
FISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLT
.| ||. | .. ...||||||||||| | ||.....||....||.. |. |||.| |.|||||.| ||..|. | . | . .. |.| |
likevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqdlh
ALEPGETITGMENEFKR
. |. . | .||..
tsvdgsgrskmtkefet
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1212-1473 | 3.4e-87 | 287.2 | In-house | 11-288 (297) | alignment | ||
Range on Protein: 1212-1473
Range on HMM: 11-288/297.0
KGNDAMLFSQEYESIEPG-QQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRT
| .. |.||. | . | ..|.| .| ||||..|. ||..|| |. ... . ||| |||..|||....|.||||||| .|. |||||||||..
kekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqev
NTIVMMTKLEERNRVKCDQYWP--TRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC-----
.|||.|...|| |.|| |||| . .....|...|. ... | |.||.. . . . |.|.| |||..|||.|||. |.|.| ... |..
lvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalav
--------NPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
.|. |||||||||.||||..| .| |.|.... |||. | ||.|| ...||.||| | . |. |
kelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1242-1472 | 5.1e-87 | 286.5 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 1242-1472
Range on HMM: 1-234/235.0
NKPKNRYANVIAYDHSRVILspmEGLPG-SDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP--TRDQEK
|| |||| ....||..|| | .| .| ||| |||| .||......||||||| .|..|||||||......|||.|.|||..|.||.|||| ......
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGFIQVTLL-DTT-ELATYTVRSFALVKNRSM-EKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERI
|| |.|.| ... . . ||.| . | |. . |||||||...|.||||||||...|.| .| .|.. . .. ||.|||||||||||| ....| .||..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
..|..||.. | ||.||. |||..|||||...|.
eaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1242-1472 | 5.1e-87 | 286.5 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 1242-1472
Range on HMM: 1-234/235.0
NKPKNRYANVIAYDHSRVILspmEGLPG-SDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP--TRDQEK
|| |||| ....||..|| | .| .| ||| |||| .||......||||||| .|..|||||||......|||.|.|||..|.||.|||| ......
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGFIQVTLL-DTT-ELATYTVRSFALVKNRSM-EKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERI
|| |.|.| ... . . ||.| . | |. . |||||||...|.||||||||...|.| .| .|.. . .. ||.|||||||||||| ....| .||..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
..|..||.. | ||.||. |||..|||||...|.
eaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1503-1770 | 7.5e-87 | 286.3 | In-house | 21-287 (305) | alignment | ||
Range on Protein: 1503-1770
Range on HMM: 21-287/305.0
ITGMENEFKRLASQkaQPSRFVSANiPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTII
.|.|...| |... . | .| . ||| |||| .|.... .|. |.. .. |||||||..|||.....||..|||| .| .||||...| . |
dkgleaqykslyee..eesidvgkk.eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvsti
VMLSKLREMGREKCHQYWPAERSA--RYQYFVVDPMSEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfGQE
|||.||.| |..||.|||| . . ... |.| || ....|| |..|.. | .|||. |.|.||||..|||.. ....| .|.|.... ...
vmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk.dkg
GPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFD
|. ||||||||||||||.... |||.. |..||.|. .| ||..|. |||| |||.|.. | |.. ..|
vpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgd
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1233-1494 | 8.9e-87 | 286.2 | In-house | 16-274 (284) | alignment | ||
Range on Protein: 1233-1494
Range on HMM: 16-274/284.0
TWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTkleernRVKCDQYWP
. ..||. || |||. ...|.|...| | .. | .||| || . ||.... |||||||| .|.||||||.||... |||..| . || ||||
dqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywp
TRDQEKYGFIQVTLLDTTELATYTVRSFALVK-NRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPP--DAGPIVVHCSAGVGRTGAYIVID
. ..|.. .| . .| . |.||.. | . . ..|...|| | |||.|||.... ..... .|. . . .|||||||||||||.|||.|
lkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivld
SMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKL
.|.|.|.|| ||.| | || ||| .|| || ||. || | | ..| .. ....|
vlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleel
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1235-1473 | 4.3e-86 | 283.5 | In-house | 2-241 (245) | alignment | ||
Range on Protein: 1235-1473
Range on HMM: 2-241/245.0
DHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTR
....|. ||.|||| ....|||.||.|||..| ..||| ||.| |||| . .||||||| || .|||||.||.. .||||.|..||..||||.||||..
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNP-PDAGPIVVHCSAGVGRTGAYIVIDSMLE
. .|| ..||||... |..|||| . ...... |.||| ..... |||||||.. ..| |...|... .. ||..|||||||||||..|... |||
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
RIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
....|..|... | || || .|||..||.|..|||.|
qlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1519-1767 | 4.3e-86 | 284.0 | In-house | 21-273 (278) | alignment | ||
Range on Protein: 1519-1767
Range on HMM: 21-273/278.0
QPSRFVSANIPANKFKNRLLNIQPYEGNRVClqpirgvegsDYINASHIDGYrqRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQ
.||.. |. . |. ||| .|.||. .||. ||||||.|||| ....||||||| .|..||||||||...|.|||| .| |.|||||.|
ipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaq
YWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDA----RDGQSRTIRQFQFTDWPEQGVPKSG--EGFIDFIGQVHKTKE-----------QFGQEGP
||| . | .| |.| .||.... |.|| ..||. |..||........ ||. ||| . |.... .... . .....||
ywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggp
ISVHCSAGVGRTGVFITLSVVLERMryEGIVDMFQTVKMLRTQRPA-MVQTEDQYQFCYHAALEYLG
. |||||||||||... . .||.. || ||....||.||.||| .||...||.|.|...||.|
vlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1198-1520 | 7.8e-86 | 283.2 | In-house | 1-321 (515) | alignment | ||
Range on Protein: 1198-1520
Range on HMM: 1-321/515.0
PIPVSQFQEHIERlkGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
|.|..|| ... . . |||.|. . . . .. | | .|||| |.. || .||.| .. | ||| || | .. ..||||.|||. .
plplaqfPafvnk..nrhttlfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkas
MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPT--RDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSmeKREVKQFQFTAWPDHGVPEHATSVLA
. ||||.|..... ||.|.|||.| ...|| .||| | |.| |.| |. . . . | . ..|. | | ||.|| |||.|||.|..|.|
vddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllk
FISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLT
.| ||. . . |...|||||||||| .| |||.. ..| ..||.. || .|..| |.|||.||| ||..|. | . | . . |.| |
likevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlh
ALEPGETITGMENEFKRLASQKAQP
. |. . | .||. | | .|
ssgdgrgrskmtkefqtlkslcpdp
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1502-1768 | 1e-85 | 283.1 | In-house | 17-289 (563) | alignment | ||
Range on Protein: 1502-1768
Range on HMM: 17-289/563.0
TITGMENEFKRLASQKAQP-SRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGS-DYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNS
. .|...||. | |. .. ... | || ||| ||| .|. || |.|. |.... |||||..||||.. .|.|||||||..|..|||||.||||.
gdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnv
TIIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKV-----TDARD-GQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTK
.||||...| | ||.||..|||.. | .|. . | ..| . | |.... . .. . ...||...|.||..|||.. . |. . ...
aiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaan
EQfgQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGS
.. . ||| |||||||||||..| |. .|.... | .|..|...|..|.||. .||||.||.| . | || . |
ka..eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1501-1766 | 3.6e-85 | 280.8 | In-house | 19-286 (307) | alignment | ||
Range on Protein: 1501-1766
Range on HMM: 19-286/307.0
ETITGMENEFKRLASQKAQPSRfVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNST
.| |...|...| ... . | . .. |..||| .|.... .|| |..| | | |||||||.| ||.... .|| |.|. .| .|||||..||..|
dtdfglakeyekLeareidkst.kvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevt
IIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARD-----GQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ
.|||||.| |. |.||..||| | .|. .|...|| ....|| ||..|. . .|| . |...| |.. ||.. .| ...| ||.. ...
livmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykl
FgqEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
..|| |||||||||.|.|..|...|.... | ||.|.||| || ||. .|| .||.|.|.| |.|
n..rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1526-1766 | 4.4e-85 | 280.2 | In-house | 4-243 (245) | alignment | ||
Range on Protein: 1526-1766
Range on HMM: 4-243/245.0
ANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERS
|. |.|| ||| .| ||. .||.|.|. | ..|||||||..||||. . .|||||||.||.|||||||||...|.||||... |.||.||.|||| . |
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges
ARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfGQEGPISVHCSAGVGRTGVFITLSVVLER
.| |.| .||.... |..|...||. .|..||.........||..||| . | ..||. |.| .. ...||. |||||||||||.||.. .||.
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae.dsngpvlVHCsaGvgRtGtfiaaylmleq
MRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
...|. |.....||.|| ||| .|||..||.|.|.|.||.|
lekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1491-1766 | 4.5e-85 | 280.3 | In-house | 3-290 (297) | alignment | ||
Range on Protein: 1491-1766
Range on HMM: 3-290/297.0
IQKLTALEPGETITGMENEFKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDF
|..| | . . |. .|.. . .... .| ....|| ||| .. |. || |. . . | ||||||...|||.|..|.||||||| .|..||
ieelvayvkekgkrGlskeyaeirnepv.eGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdf
WRMLWEQNSTIIVMLSKLREMGREKCHQYWP--AERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQ
|||.|||. .||| .. |.|| || |||| | ||.. . | .. .. .| | ..........||.. |||. ||. |||.|.. ..|.. .
WrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlek
VHKTKEQFG-----------QEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
| ... .. .. || ||||||.|||| |||| . |.|.. .| ||...|||.||||| ..||..||.||| | |||
vrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1216-1474 | 4.9e-85 | 280.5 | In-house | 7-271 (278) | alignment | ||
Range on Protein: 1216-1474
Range on HMM: 7-271/278.0
AMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVIlspmeglpgsDYTNANYCDGYrkQNAYIATQGPLLETMADFWRMVWEQRTNTIVM
.|... .. . .|. .. ..... |..|||| ....||||||. || ||.| ||| ....||||||| .|.||||||.||.....|||
ldlllefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivm
MTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKN----RSMEKREVKQFQFTAWPDHGVPEHA--TSVLAFISRVKSCNP----
.|.|.|..|.||.|||| .. . || ..||||....| .||.| . .. . |.|.|...... |||||||.. .|.| .. ......
ltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllas
---------PDAGPIVVHCSAGVGRTGAYIVIDSMLERIkhEKTVDIYGHVTCLRAQRNY-MVQTEEQYIFIHEALYEA
.. ||..|||||||||||...... |||.. |..||.. |. || ||.. .||..|||.|..|.|.|
lllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllel
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1502-1765 | 8.3e-85 | 279.9 | In-house | 32-291 (319) | alignment | ||
Range on Protein: 1502-1765
Range on HMM: 32-291/319.0
TITGMENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTI
.| .| ||.|.. . .. . ||.. || |||. || ... |.| |... |.|.|||||||...||.... |||.|||| .| .|||||.||.|..
dltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncst
IVMLSklremgREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEG
||.|. ..|| |||| . ... | |. | . .|..|...... .. . | |.|| | ||..|||... .. .. .|.. ... ..
ivllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhra
PISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE-Y
.| ||||||||||||.|.| |.|.||. | ||....|. || ||. .|| ||.|.| | || .
nivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1526-1772 | 1e-83 | 275.4 | In-house | 4-248 (250) | alignment | ||
Range on Protein: 1526-1772
Range on HMM: 4-248/250.0
ANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREkCHQYWPAERS
|. |.|| ||| .| ... || |.. .| . |||||||...||..|.|.||||||| .|.||||||..|..|. ||||..|.|.... .|||||.|..
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka
ARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfGQEGPISVHCSAGVGRTGVFITLSVVLER
.| |...|. .. |. |..|.. |. ..|..||..|. ||..|||. . .... .|.....| ...|. |.|||||||.| ||... ||||
ekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqq.agnaPvivqCsaGvgrsGafiaidavler
MRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFDHY
.. | .||.|. .|.||..|| .|....|| |.|...|..| |.. |
lkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedy
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1217-1473 | 2.9e-83 | 274.4 | In-house | 26-295 (306) | alignment | ||
Range on Protein: 1217-1473
Range on HMM: 26-295/306.0
MLFSQEYESI---EPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSpMEGLPGSDYTNANYCDGY--RKQNAYIATQGPLLETMADFWRMVWEQRTN
|..|.|.. | .... .... .|| |||| |.. .||.||||. ...||||| |||| .. ....|||||| | .|..|||||||.. ..
agfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensr
TIVMMTKLEERNRVKCDQYWPTRD-QEKYGFIQVTLLDTTELATYTVRSFALV-KNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC----NP
|||.|| ||.. || .|||. .|.|| |.|| .. ..||.|..|.. . |... |.||| |..|..|||||||.. ||.|.. |.. .
vivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeelee
PDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK---TVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
.|||||||||||.||||..|||| .|. |.... .||. | .|.||. .||||.|| |...|. .
aeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikk
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1508-1765 | 8.3e-83 | 273.1 | In-house | 2-255 (284) | alignment | ||
Range on Protein: 1508-1765
Range on HMM: 2-255/284.0
NEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSk
||.|.. . .. . ||.. || |||. .| ... |.| |... |.|.|||||||.| ||.... |||||||| .| .|||||.||.|.. ||.|.
vefrracklgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.
lremgREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHC
..|| |||| . ... | |. | . .|..|...... .. . |.|||| | ||..|||... .. .. .|.. ... .. .| |||
.....kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhc
SAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE-Y
|||||||||.|.| |.|.||. | ||....|. || ||. .|| ||.|.| | || .
sagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1505-1764 | 9.2e-83 | 272.6 | In-house | 23-275 (314) | alignment | ||
Range on Protein: 1505-1764
Range on HMM: 23-275/314.0
GMENEFKRLASQkaqpsrFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
|. .|.. | . .|. |. ||| .| .|. || |..| | ||||||. ||.|.. .|.|.||||| ||..||||.....|.. |||
gfkeeyeslfeg......wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivm
LSKLREMGREKCHQYWPAERSArYQYFVVDPMSEYNMPQYILREFKVTDARDG--QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfgQEGPI
|..| | || || .||| . . |. . | .. ... | |.|. . | . |..|||||. ||. .||.| .|..... .|.|..|. ..|.|
ltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..eaGri
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
|||||| ||||.||....||. .. ||.||.|..|| ||.... ||.||.||.|.| ..||
vvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1531-1764 | 1.5e-82 | 272.0 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 1531-1764
Range on HMM: 1-235/235.0
NKFKNRLLNIQPYEGNRVCLqpiRGVEG-SDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWP--AERSAR
|| ||| .| ||. .|| | .| || ||||||....||.. ...||||||| .| ||||||.|......|||| .| |.|||||.|||| |.| .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YQYFVVDPM-SEY-NMPQYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqFGQEGPISVHCSAGVGRTGVFITLSVVLE
|. . | . .| .. .|.||...... . ..|...|...|.||..|||.| ....|.| .|.|.| ..||. |||||||||||.|..|...||
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGvgRtgtfvaldille
RMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
... |. ||..|.||.||.||| |||...||.|.|.| ||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1531-1764 | 1.5e-82 | 272.0 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 1531-1764
Range on HMM: 1-235/235.0
NKFKNRLLNIQPYEGNRVCLqpiRGVEG-SDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWP--AERSAR
|| ||| .| ||. .|| | .| || ||||||....||.. ...||||||| .| ||||||.|......|||| .| |.|||||.|||| |.| .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YQYFVVDPM-SEY-NMPQYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqFGQEGPISVHCSAGVGRTGVFITLSVVLE
|. . | . .| .. .|.||...... . ..|...|...|.||..|||.| ....|.| .|.|.| ..||. |||||||||||.|..|...||
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGvgRtgtfvaldille
RMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
... |. ||..|.||.||.||| |||...||.|.|.| ||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1501-1763 | 1.3e-81 | 268.8 | In-house | 18-276 (288) | alignment | ||
Range on Protein: 1501-1763
Range on HMM: 18-276/288.0
ETITGMENEFKRLASQKAQPSRFvSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNST
.. ||...|.. ||. . . | .. . |. ||| || ||. .|| |. ..|.||||||.|||......|||||||||.| .|||.. .|....
rnrtgfseeynsLaalektksvt.agrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenkts
IIVMLSKLREMGREKCHQYWPAERS-ARYQYFVVDPMSEYNMPQYILREFKVTdaRDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFgqE
||||..| | |..||..|||.. .| . | ... .. ...||.. . .... ..| |.|.. ||..|||.| . ..... ||. ....
tivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad..t
GPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAAL
||| |||||||||||.||.| ...... | .|.. ||. || ||. .|||. ||.|.|.. |
gpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1481-1766 | 1.7e-81 | 268.6 | In-house | 3-297 (306) | alignment | ||
Range on Protein: 1481-1766
Range on HMM: 3-297/306.0
EVHARNLYGHIQKLTALEPGETITGMENEFKRLASQKAQP-SRFVSANIPANKFKNRLLNIQPYEGNRVCLQpIRGVEGSDYINASHIDGY--RQRNAYI
.. |... ....|. | . .|.|.||..| ..|. .. | || ||| || |.. .|| |. .| |||||||. |.. ....||
sllakeieqrvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyi
ATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSAR-YQYFVVDPMSEYNMPQYILREFKVT-DARDGQSRTIRQFQFTDWPEQGV
|||| | .| .|||||.|..||..|||. | | |.||| .|||.| . . | | .|| .. .|||||..|. .....|...|..|..||..||
atqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgv
PKSGEGFIDFIGQVHKTKEQFG--QEGPISVHCSAGVGRTGVFITLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
||. . ..||. .|.. .|.. ..||| ||||||.|||| || . ..|. ....|. .|. ..||..|.|| .||||.||.| |.| .|.
pkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyi
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1195-1485 | 1.8e-79 | 262.0 | In-house | 6-294 (297) | alignment | ||
Range on Protein: 1195-1485
Range on HMM: 6-294/297.0
SHPPIPVSQFQEHIErlKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKqnAYIATQGPL
|||.|.| .. |. .. .||.|. . . .. .. | .|.||.|.. || |||.| .. | ||| || . |... .|.|| |
errpiplsdfatlvq..knrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPm
LETMADFWRMVWEQRTNTIVMMTKLEERNRvKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPE--HATS
.|.||||.||......||||.....||.. || .||. . ..| . |.|| ..| . |.. . |... .| |||.||. |||. |.. .|.|
katvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsass
VLAFISRVKSCNPPDAG-PIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHAR
.| .|| |. | |..|||.||||||| .. |||.. ..|.||.|||.| |. || .| |.|||.||| |...|. ||. | |...|
llklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqas
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1234-1473 | 1.6e-78 | 258.9 | In-house | 2-240 (243) | alignment | ||
Range on Protein: 1234-1473
Range on HMM: 2-240/243.0
WDHSNLETNKPKNRYANVIAYDHSRVILspmeglPGSDYTNANYCDGYRKqnaYIATQGPLLETMAD----FWRMVWEQRTNTIVMMTKLEERNRVKCDQ
. ...|. |..|||| ....||||||.| .|||| |||....... .||||||| || .| ||||.||.....|||.|.|.|..|.||.|
fsiallpenlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq
YWPtrDQEKYGFIQVTLLDTTELATYTVRSFALVKNR-SMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC--------NPPDAGPIVVHCSAGVG
||| ... || ..||||....|. |||| . |. . ..|.| ......|||||||.. ...|.|.. |... . .. ||..||||||||
ywp..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTGAYIVIDSMLERIkhekTVDIYGHVTCLRAQRNY-MVQTEEQYIFIHEALYE
|||..|... ||... .||.. | ||.||.. .|||..||.|..|||.|
RtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1202-1483 | 1.7e-78 | 259.0 | In-house | 5-287 (439) | alignment | ||
Range on Protein: 1202-1483
Range on HMM: 5-287/439.0
SQFQEHIERLKGNDAMLFSQEYESIEP---GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETM
..||||.|.|. |. .|....|.|. . | ...|||| .| |.||.||.| . |.| | | |||| .|| ... ||||||| ||
defqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkett
ADFWRMVWEQRTNTIVMMTKLEERNRvkcdqYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEK--REVKQFQFTAWPDHGVPEHATSVLAF
||||.|.|..| ||||.|.| | . |||. .. || | | || |..| | ....| . | | ||...||||. || .|. || |
ddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldf
ISRVKSCNPP-DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVH
. ..|.| . ||.||||||||||||. | .| ||..| |. ||| | |. || ||. |||. ||.||..|. | . | . |
lrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavt
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1503-1772 | 3.1e-78 | 257.6 | In-house | 19-289 (290) | alignment | ||
Range on Protein: 1503-1772
Range on HMM: 19-289/290.0
ITGMENEFKRLASQKAQpSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEG--SDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNST
.|..|.||.| | . . .. . || .|| || .|. ||. |.|| | . .||||..|.||.....|||||||. .| |||...|....|
negfrnqfkmldsgese.htvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvt
IIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARD-GQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqE
||||| . |.|..||.||||.. ...|..| . ..| .. .|| |...|.. . |..... |.|.| |...| . .. . | .. ||. . | .
iivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrg.n
GPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFDHY
..| ||||..|||..||... . ..... || .|.|| .| .|.|.| .|||..|||. .. |.|| ||. |
tsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1230-1477 | 1.1e-77 | 255.7 | In-house | 28-279 (290) | alignment | ||
Range on Protein: 1230-1477
Range on HMM: 28-279/290.0
QQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQ
.... .... |.|. |||| ... ||.||| || .|. .|||| |||. | .. .|||.|||| .|. |||||.||.... .||. .. | .. ||..
kvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
YWPTRDQEK--YGFIQVTLLDTTELA-TYTVRSFALVKNrsMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYI
||| . .|. .| ..||| . . ...|.... .. |.|.|.||..|||||||||. |.|.|..|. |.. . .. |.||||||||||||. |
YWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtii
VIDSMLERIKHEKT---VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVAS
.|| . | .|.||. .|.. |. || ||. .|||.||| ....|. | | .
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqk
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1520-1766 | 2.4e-77 | 254.7 | In-house | 26-277 (290) | alignment | ||
Range on Protein: 1520-1766
Range on HMM: 26-277/290.0
P---SRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKC
. ... . |. ||| .| ||. .|| |. |...||||||||..| | .. .|||.||||..| .|||||.||.| .|.||. .. |.|. ||
aekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkC
HQYWPAE--RSARYQYFVVDPMSEYNMP-QYILREFKVTDArdGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPISVHCSAGVGRT
..||| | .. ... | |. ..| .. ....| .||. ..||...||..|.||..|||.| . ...| .|....| .. |. ||||||||||
erYWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..sedaPlvvhCsaGvGrt
GVFITLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|. |.. | | .. | | .|.|. | ||.||.|.|||..||.. |.| .|..
Gtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1525-1766 | 7.6e-77 | 253.4 | In-house | 4-242 (243) | alignment | ||
Range on Protein: 1525-1766
Range on HMM: 4-242/243.0
SANIPANKFKNRLLNIQPYEGNRVCLqpirgvEGSDYINASHIDGYRQrnaYIATQGPLAETTED----FWRMLWEQNSTIIVMLSKLREMGREKCHQYW
|..|.|. ||| .| ||. .||.| ||||||||..|..... .||||||| ||.|| |||||||...|.|||| .| |.|||||.|||
iallpenlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PaeRSARYQYFVVDPMSEYNMPQYILREFKVTDAR-DGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ------FGQEGPISVHCSAGVGRT
| . .| |.| .||.....|..|..... |...|........ ||..||| | | ..||. .|.. |. ..||. ||||||||||
p..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GVFITLSVVLERMryeGiVDMFQTVKMLRTQRPA-MVQTEDQYQFCYHAALEYL
|..|.. ..|... | ||....||.||.||| .|||..||.|.|.|.||.|
Gtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1199-1478 | 8.2e-77 | 252.9 | In-house | 2-286 (290) | alignment | ||
Range on Protein: 1199-1478
Range on HMM: 2-286/290.0
IPVSQFQEHIERLKGNDAMLFSQEYESIEPGQ-QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPG--SDYTNANYCDGYRKQNAYIATQGPLL
|||..| |... . . | ....... |. ..| . . . ||..||.||.. || |..| |. | . .| || | .||.....|||||||.
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
ETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRS-MEKREVKQFQFTAWPDHG-VPEHATSV
.|..|||...|.... |||.|. | ..||| ||||..|...|| ....||. ..| .|. | . . ...| .|..|.|.|.|.|...| |....|..
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtil
LAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASG
|.. ..| . ..||||||..|||.. ..... ... | | .|.. . .| |. .|||..|| .|.. . ... |
lvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsf
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1241-1474 | 1.4e-75 | 248.5 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 1241-1474
Range on HMM: 6-239/239.0
TNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRdQEKY
|| ||||||...||||||.| . | ||| ||.| | .||||||| . . |||||.|..| |||.| | | . || |||| ||
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.tsky
GFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK
..||| | .| | .|.| . . |.| | |..|| |||.|||..||.|| . .. . | | | |.|||||||||||..|||.|| . |..|
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqk
TVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
||||. .| ..| .| .|||| |||.||| |. ||
tvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1502-1766 | 2.1e-75 | 248.4 | In-house | 13-276 (281) | alignment | ||
Range on Protein: 1502-1766
Range on HMM: 13-276/281.0
TITGMENEFKRLAS-QKAQPSRfvSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNST
.|. .|.. ||. . .... ... ..|. ||| || |. || ..| . .|||||....||.. ..|||||||. .. ..||.|.|||. .
dnaGfieeyeklaaigvdntat..askadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvs
IIVMLSKLREMGREKCHQYWPAER-SARYQYFVVDPMSEYNMPQYILREFKVtDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQe
.|||. . | |. |||.||| .. . .| ..| ..| . ..|| |.||. ....|..|...|...| ||..|||.. . ...| .|.|..|. .
aivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktk.
GPISVHCSAGVGRTGVFITLSVVLERMR-YEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|. .||||||||||..|.| ..... . .|. ..|. || .| |||| ||.| |.| |..|
aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1233-1473 | 2.7e-75 | 248.0 | In-house | 19-266 (274) | alignment | ||
Range on Protein: 1233-1473
Range on HMM: 19-266/274.0
TWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGL-PGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQY
. .. .. .. |||| ... ..|||.|.. .. . |.| |||| ||.. ..||.|||||| .|.||||||....... |||.|||.|.|. || .|
dqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavy
WPTRD----QEKYGFIQVTLLDTTELATYTVRSFALVKNRSmeKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCN---PPDAGPIVVHCSAGVGRTG
.|.. .|.|| .... ...| |.||.. | . . .|.|| . .|.|||| .|..|...| .. |.. . ..|.|||||||.||||
fPdaedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtG
AYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
..| |. . ....|..||. . |. || .| ||||.||| .||.||..
cfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1241-1472 | 4.1e-75 | 247.0 | In-house | 7-238 (239) | alignment | ||
Range on Protein: 1241-1472
Range on HMM: 7-238/239.0
TNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRdQEKY
|| ||||||...||||||.| . | ||| ||.| | .||||||| . . |||||.|..| |||.| | | . || |||| ||
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.tsky
GFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK
..||| | .| | .|.| . . |.| | |..|| |||.|||..||.|| . .. . | | | |.|||||||||||..|||.|| . |..|
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqk
TVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
||||. .| ..| .| .|||| |||.||| |.
tvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1235-1475 | 6.4e-74 | 243.6 | In-house | 30-269 (273) | alignment | ||
Range on Protein: 1235-1475
Range on HMM: 30-269/273.0
DHSNLETNKPKNRYANVIAYDHSRVILSPMEGlpgsdYTNANYCDGYRK--QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP
. .. . || |||| ||. ||..||.|. | | ||.. . |||.|||| ||..|||.|||||... |.|.|. |...|||..|||
evgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywP
TRDQEK---YGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPpDAGPIVVHCSAGVGRTGAYIVID
. ..| .. ..|.||....| ...||..|. ...| | ||| ...|..||||||| .|...| |...|.. . ||||||||||||.||.|..|.||
esknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitid
SMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
.|. |...| .|. | .|| ||. .|||..||||...|. |..
vvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1232-1475 | 8.2e-74 | 243.0 | In-house | 31-275 (280) | alignment | ||
Range on Protein: 1232-1475
Range on HMM: 31-275/280.0
FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEglPgsDYTNANYCD----GYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKC
. ..... | .|||| ....||. ||.|. | || |||| . . | |||||||| .|..|||.|||||....|||.| | || ||||
laisaarkpenlsknryrdilpydatrvklkese..t..dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkC
DQYWPTR-DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYI
||||. |. .|| ..|.. . | .| .| . | .... |.|.. |.|..||||||||......| |..||... . |.|||||||.|||| .|
hqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvli
VIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
... | | ... | . | .| || .|||..|| |. ||. ..
lletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvy
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1199-1510 | 1.5e-73 | 242.8 | In-house | 5-323 (325) | alignment | ||
Range on Protein: 1199-1510
Range on HMM: 5-323/325.0
IPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETM
| | .. ||.|. | .| |..|.. . . . . . . || |||. ||.|.|.|||.| .. | ||| ||.| ..|.. ..|.| || .|.
iavvnlvehvekkkaqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltati
ADFWRMVWEQRTNTIVMMTKLEERnRVKCDQYWPTR--DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAF
|.||.| . |. .|.. .|.. .| .||| . . ..| ..| | |.. | | . . . . | | |||||. .|.| ||... ......
ndlWrlvldWrcsvvvvlneldlg.kdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisi
ISRVKS------CNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGH
. || .| ..||.|||||||||||..| . |.|... .| |||.| | ||..| ||.| .|||.|.||| ||. || |.| .. .
lqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeak
IQKLTALEPGETITGMENEF
. | .| .|.||
lsslqernpltqklniekef
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1241-1472 | 4.5e-73 | 240.4 | In-house | 2-236 (237) | alignment | ||
Range on Protein: 1241-1472
Range on HMM: 2-236/237.0
TNKPKNRYANVIAYDHSRVILSPMEGlpGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQE-K
|| ||||.|..|||||||.| . |||| ||.| .|. . |||.|||| . |||.|||... |||.| | |.|..|| .||| ||
enkiknrygnivaydhsrvvlkgags..gsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGFIQVTLLDTTELATYTVRSFALVKNRSM-EKREVKQFQFTAWPDHGVPEHATSVLAFISRVKS--CNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERI
|| . |.| |.. |||||. |.|. .. | | ..|.|||.|||.|||......| | .. ...|| ..|||||||||| ..|||.|| .
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
| .| |||| .| .. .| |..||..||.|||...
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1492-1772 | 1.1e-72 | 239.4 | In-house | 8-284 (287) | alignment | ||
Range on Protein: 1492-1772
Range on HMM: 8-284/287.0
QKLTALEPGETITGMENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpirgVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFW
...| .. . .| .| |. | . . .. . . || |||| .| ... .|| |. | |||||..||||....|.|....|...| .||
gefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfW
RMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDAR-DGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVH
......| |.||||....| .|.|.|||| |.| . . . ..| . .|| |...|. .|. ....|.|.|.|...| .. . . | .
kliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemy
KTKEQFGqEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFDHY
||. . | ...| ||||..|||...|. . ... . ||..|.|| .| | |.| .||| .||.| ... |||| ||. |
ktqrkrg.ntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfety
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1510-1762 | 5.7e-72 | 237.0 | In-house | 21-271 (280) | alignment | ||
Range on Protein: 1510-1762
Range on HMM: 21-271/280.0
FKRLASqKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpirGVEGsDYINASHI----DGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
|..| | . |. |.| ||| .| ||. || |. | |||||... .. . | |||||||||.|..|||.|.|||.|..||||
feqlyr.kkpglaisaarkpenlsknryrdilpydatrvklk...eset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml
SKLREMGREKCHQYWPAE-RSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPISV
| | || ||||||| . . .| | | .| . .|.|||. ..|.. ..|.| |.|...||..|||.. . |..|. .|.|... |.| |. |
ttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrs..gkeePvvv
HCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAA
|||||.|||||.|.| . | . . | . . |...| || ..|||..||.| .|
hCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1199-1482 | 2.2e-71 | 235.2 | In-house | 2-285 (287) | alignment | ||
Range on Protein: 1199-1482
Range on HMM: 2-285/287.0
IPVSQFQEHIERLKGNDAMLFSQEYESIEP-GQQ-FTWDHSNLETNKPKNRYANVIAYDHSRVILSpmegLPGSDYTNANYCDGYRKQNAYIATQGPLLE
|||..| | ... . . |.. . .| .|. |. . ||.|||..... .| ||.| || || . |||....|.|....|. .
ipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfn
TMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNR-SMEKREVKQFQFTAWPDHG-VPEHATSVL
|. .||....... ..|||.....| .. .| ||||. . .| ...||. . | |..| . . .. . .|..|||.|.|.|...| |.|..|..|
tarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtill
AFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEV
. ..|. . ..||||||..|||.. .. .. ... | | ..|.. . | |. .||| |||.|| ... | . |..| .
vieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1530-1766 | 2.4e-71 | 235.4 | In-house | 42-276 (515) | alignment | ||
Range on Protein: 1530-1766
Range on HMM: 42-276/515.0
ANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPA--ERSAR
| ||| || ||. .|| |. | |||.|||.| .. .||||.|||. ...||||.....| | |.|..||.| . || .||| | .
infkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvk
YQYFVVDPMSEYNMPQYILREFKVTDARDgqSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqeGPISVHCSAGVGRTGVFITLSVVLERMR
. .. |. .| . | |...|. | |||. ||.||.||..|||| .. .| .| ..|. |. .|||||||||||.|.. |. ...
fGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt..hpliihcsaGvGrtGvvisidsvvahak
YEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
.||.|..|. .| .|| .|||..|| | | | ||.|
ttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1519-1766 | 2e-69 | 228.9 | In-house | 32-277 (315) | alignment | ||
Range on Protein: 1519-1766
Range on HMM: 32-277/315.0
QPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQ
...| .| . | ||| || |.. .|| |. | |||||||.| .. . .||||.|||| . .|||||..... | |||..|..| . || |
diyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrq
YWPA--ERSARYQYFVVDPMSEYNMPQYILREFkVTdARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfgQEGPISVHCSAGVGRTGVF
||| |... . |. .| . . |.. || . .|||. |||||.||..||.| .. .| .| ... .| .. ||||||||||||.
ywPdrkadsvefGsikvellsleadtdgvarkl.vt.rkseesrtvtqfqftewPdkGvdkqtssllklikevkadngk..kefsllvhcsaGvGrtGvv
ITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|.. |..... . ||.|..||.||..|| .||||..| | | | ||.|
isidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1525-1767 | 2e-69 | 228.8 | In-house | 22-269 (274) | alignment | ||
Range on Protein: 1525-1767
Range on HMM: 22-269/274.0
SANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEG-SDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPA
... .. ||| .| | | ||.|.. . . |.|||| .| ||.. .||.||||||..| .|||||........|||| ||.|. ..||..|.|
eldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPd
ERSA----RYQYFVVDPMSEYNMPQYILREFKVTDARDgqSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQE-GPISVHCSAGVGRTGVFI
.... ||. . . . . .| .|.. . . . .|.. . .||||.. .|.. . ..|.. .|....|. .. .|. ||||||.||||.||
aedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfi
TLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLG
. |. . ..| |..||....| || .| ||||..||.. ..| .||
aisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1507-1768 | 3.2e-69 | 228.2 | In-house | 14-271 (273) | alignment | ||
Range on Protein: 1507-1768
Range on HMM: 14-271/273.0
ENEFKRLASQKAQPSRfVSANIPANKFKNRLLNIQPYEGNRVCLQpirgVEGSdYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
..||| | |.. . ... .|| ||| |. ||. || |. ||. |||||.| .. |||.|||| ||..|||.|.|||....|.|
aeefkelrelkpldtc.evgkkkenkdknryrnvlPydetrvklg....degg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviam
LSKLREMGREKCHQYWPAERSAR---YQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgQEGP
... .| |. |||.||| ... . .. . |. . .. .. .|...|.| . |.|| . ...|..||. |||.| . .. |. .| . .. ..||
vtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt...dagP
ISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGS
| ||||||.||.|..||. |||. . . .|. ..|. || || ..|||.||| |.|.|.|| |.|
ivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlks
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1198-1515 | 1.5e-68 | 226.0 | In-house | 3-277 (392) | alignment | ||
Range on Protein: 1198-1515
Range on HMM: 3-277/392.0
PIPVSQFQEHIERLKgnDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLET
||||.|| .|. . . ||..|. . . . .. | |..|||| |.. || .||.| .. | ||| || | ... ..||||.||| .
pipvaqfpafveknr..hsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaas
MADFWRMVWEQRTNTIVMMTKLEERNrvkcdqywptrdqekygfiqvtlldttelatytvrsfalvknRSMEKREVKQFQFTAWPDHGVPEHATSVLAFI
. ||||||..... ||.|.|||.| . . ..| | ||.|| |||..||.|..|.| ||
lddfwrmvfqenvttiamvtklkegd..........................................kgddartvaqfhftewPdkdvpkhtssllkfi
SRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYGHIQKLTAL
||. . |...|||||||||| | |||.. . |. . ||.. || .| .| |||||.||| ||. |. | . | . . |.|.| .
kevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlsts
EPGETITGMENEFKRL-AS
|.. . . ||. | ||
sdGdvrskqlkefrslkas
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1530-1769 | 2e-68 | 225.7 | In-house | 50-287 (297) | alignment | ||
Range on Protein: 1530-1769
Range on HMM: 50-287/297.0
ANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQrnAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGReKCHQYWPAERSARYQ
| |.| || ||. .|| |. . |||.|||.. |... .|.|| | .| .|||.|..... ..||||... | . || .||. . .. .
vnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfG
YFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPK--SGEGFIDFIGQVHKTKEQFgQEGPISVHCSAGVGRTGVFITLSVVLERMR
. .| .| . .| ||..|| . . | ..|.||..||.. |.. | . ....| .|.|. .| .|||. |||.||||||||..|. |. ...
dvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqn.aegPllvhclaGvGrtgvlltidsvvaeak
YEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSF
| ||.|..||.|| .|| .|||..||.| | | ||.| |
rekevdifglvkklrqerpylvqtkeqykfvyvavleallse
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1503-1767 | 1.6e-67 | 223.0 | In-house | 22-289 (325) | alignment | ||
Range on Protein: 1503-1767
Range on HMM: 22-289/325.0
ITGMENEFKRLASQKAQpsRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTII
|. .||. | |. .. . | |.|| |||. |. ... .||.|. . |||||||.. ..... ..|.| ||..|..|.||.. . .....
qdgfahefgllpsddgi..akkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvv
VMLSKLrEMGREKCHQYWPAE--RSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQ--
|.| .| . | ..| .||| | | .. . | .. .. |. | ..| ....|..|...|||. |.. ||.| .| .. |.. .|.
vvlnel.dlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtant
--EGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLG
.|| ||||||||||||||.| .|... | ||.|. || || .||.||.| ||| ..|.| |..
kastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaym
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1503-1765 | 5.4e-67 | 220.6 | In-house | 14-279 (288) | alignment | ||
Range on Protein: 1503-1765
Range on HMM: 14-279/288.0
ITGMENEFKRLASQKAQPSRFVSANIP-ANKFKNRLLNIQPYEGNRVCLQpirgVEGSDYINASHIDGYRQR-NAYIATQGPLAETTEDFWRMLWEQNST
|.....|| | ..... .| | | . ||| .| ||. |||.|. . ||||||.. . .||||.||..| |||.|..|| |
ktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkss
IIVMLSKLREMGREKCHQYWPAERSA--RYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHK--TKEQF
.|||| . |.|..|...|||... . ... . | |. ...... |..|.. . . .... |.| ||| |||.| | ...|...|.. ...|
viVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqr
GQEGPISVHCSAGVGRTGVF-ITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
. |. ||||||||||||| . ..| | . .|..|. | |. ||.|| |||...|..|.|.| ||.
ksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1508-1766 | 2.6e-66 | 218.7 | In-house | 27-296 (300) | alignment | ||
Range on Protein: 1508-1766
Range on HMM: 27-296/300.0
NEFKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVeGSDYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
|. |.. ... . . .|. | |. ||| .. ||| ||| |.| . ..|||||.| .. ||..|||| | .|||.|.|||. ..||||
teyeripkkre.dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivml
SKLREMGREKCHQYWPAE----RSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEG-
. .| |.||...|.| . ...... | | . ...| . .|. .. ||. .|.||||..|||. .||.... .|. .... .|
teeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseve
------PISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|. |||||||||||| |. .... . . .|. .....||.|| .||| ||.| |.. ..||
skeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1229-1475 | 1.6e-65 | 215.7 | In-house | 19-271 (290) | alignment | ||
Range on Protein: 1229-1475
Range on HMM: 19-271/290.0
GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGlpgsDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCD
..|. ...|..|...||| .| |||||..| . || ||. . . . || ||||| .|.. ||.|||||.. ..||. |. |....||
asdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikca
QYWPTRDQEKYG-----FIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKS--CNPPDAGPIVVHCSAGVGR
||||. ..|| ..|.|. . . .|||| . | . .. | ||. .| .|.||| |||| .. | |. .|.. . .| || |.|||||.||
qywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGr
TGAYIVIDSMLERIKHEKT---VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
.|.....|..| .|.... ||| .. || .| ..|| .| | . |. | .
sGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGa
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1504-1765 | 4.1e-65 | 214.8 | In-house | 24-278 (315) | alignment | ||
Range on Protein: 1504-1765
Range on HMM: 24-278/315.0
TGMENEFKRLASQKAQPSRfvSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
|...... . . .| . |. || ||| || .|. || | . ..|||.||. |||| ... |||.|||.... .||||...|.. . ||
ngfkqdyesipggqlhpld..vakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkiv
MLSKLREMGREKCHQYWPAErSARYQYFVVDPMSEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqeGPIS
||..| | ..|. .||| . | . | .|| .| | . |. . . |.. |...| ||. ||||. ....| .|.. ... |.|
mltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvvf..gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv..gaiv
VHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||||||||| ||||. ||... | ..|... .. .| .| |||. .|||| | | ||
vhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydallet
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1531-1766 | 2.3e-64 | 211.9 | In-house | 42-290 (296) | alignment | ||
Range on Protein: 1531-1766
Range on HMM: 42-290/296.0
NKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGReKCHQYWPAERSARYQY
|. ||| .. ||. ||| |. . | | ||||||...|.. . ..|| |..| || ..|||....... .|.|.| .. . ....||| . ..|.
nreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyge
FVVDPMSEYNMPQYILREFKVTDA----------RDGQSRTIRQFQFTDWPE-QGVPKSGEGFIDFIGQVHKTKEQF---GQEGPISVHCSAGVGRTGVF
..|. ..| .... |.||.| . . |....||.| |. . || | ...|... .|.. .|. .|||. |..| |..|.||.
ifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvy
ITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
... . || .. |. ||.|. ||.|| .|| .|.. ..|...| ||..
laidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1219-1478 | 3e-64 | 211.5 | In-house | 19-293 (296) | alignment | ||
Range on Protein: 1219-1478
Range on HMM: 19-293/296.0
FSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTK
. .|.. .. .. . . ..|. |||. .|. ||. ||.|. ..| ||| || | |.. |...|| |..| ||. .|||.|... ....|..||
yklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtk
LEERNRvKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKN----------RSMEKREVKQFQFTAWPD-HGVPEHATSVLAFISRVKSC----
. .. .. .||| . .|.|| | | .. . ..| . | | |.|. ..|.| ||.||.| |. . || ..... .. ||..
tfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekv
-NPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASG
. |. ||.||..| |..|.|.|. || || ...|. ||... | || .|. .|.. |.| .| . | ||| .
dedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcn
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1510-1766 | 5.1e-64 | 210.9 | In-house | 1-264 (270) | alignment | ||
Range on Protein: 1510-1766
Range on HMM: 1-264/270.0
FKRLASQKAQPSRFvSaNIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKL
||.| .....| . .. .| || .| | ||.|.... . . |||| .. |. . ...|||..|||. |...||||.||...| |||...|
fkeldkeetsesdl.p.eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgl
REMGREKCHQYWPAERSA----RYQYFVVDPMSEYNMPQYILREFKVTdaRDGQSRTIRQFQFTDWPEQGVPKSGE------GFIDFIGQVHKTKEQFGQ
| ||.|| .|||||. .. | .|| .. |||.. ... ..|..| . |....||..|||.. . . . .|....... .
eEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldk
EGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
..|. |||||||||||..|.| ... . .. ||. . .. || .|.|.||. .||.| |.| .||
aePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1238-1473 | 1.3e-63 | 209.5 | In-house | 16-262 (270) | alignment | ||
Range on Protein: 1238-1473
Range on HMM: 16-262/270.0
NLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQ-NAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ
. ..| ||||... ..||.|...| . . | |||| |. .. ..|||..||| |. .||||.||.....|||.|.|||..| ||..|||.. .
eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk
E----KYGFIQVTLLDTTELATYTVRSFALVknRSMEKREVKQFQFTAWPDHGVPEHAT------SVLAFISRV-KSCNPPD-AGPIVVHCSAGVGRTGA
| ..|.|.|. | .. | .. | .. |.|.. |....|||||||... ..|. . | .|.. | |.|..|||||||||||
ekvkledgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGt
YIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
|..| ... ....| ||. .. || .| .||. ||| |...|. |
lialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1505-1764 | 3e-63 | 208.3 | In-house | 30-290 (297) | alignment | ||
Range on Protein: 1505-1764
Range on HMM: 30-290/297.0
GMENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQR-NAYIATQGPLAETTEDFWRMLWEQNSTIIV
.|.|.. |.. .|.|| |. . | ||| .. ||. .|| |. | ||||||| | | ||||||||||.| |||.|.||| ...||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvviv
MLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNM-PQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPI
.|..|.| | ..|..||| | |. |. . |. .||. .|..| | . . . ..||. || | |||.||| | ...| .| |. |. ||
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr..Grscpi
SVHCSAGVGRTGVFITLSVVLERMRyEGI--VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
||||.|.|||||.| . .||.|. |. .|. |.. || ||| .|.|.||..|.. | |
vvhcsdGaGrtGvyilidlvlnrll.kGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1504-1768 | 7e-63 | 207.1 | In-house | 15-295 (301) | alignment | ||
Range on Protein: 1504-1768
Range on HMM: 15-295/301.0
TGMENEFKRLASQKAQPSRFVSANipANKFKNRLLNIQPYEGNRVCLQPIRG--VEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTI
...|...|.| ... ... . .|| || ||..|. ||. |.| . . .|||||.||||......||.|||. .| ||||..|.. .
nkfeeqykelkegedksctvglse..enkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
IVMLSKLREMGREKCHQYWPAERSAR--YQYFVVDPMSEYNMPQYILREFKVT--D-------------ARDGQSRTIRQFQFTDWPEQGVPKSGEGFID
|||. .|.| ..||.|||| . . . | | ..|...|....|...|. | .| .|... |.| ||||..|| . .
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLq
FIGQVHKTKEQFGqEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGS
| .| ... . | ||. ||||..|.|.||....|. || . ||.||.|| .| .| ..| .|.| .|| . | . .||
viddvihrqqkig.ggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylql
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1215-1475 | 8.2e-62 | 203.6 | In-house | 16-293 (301) | alignment | ||
Range on Protein: 1215-1475
Range on HMM: 16-293/301.0
DamlFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGL--PGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNT
. |...|.... |.. . . . |.||. ||. |. ||. |.||.|.. | .|.||.| |||......||.|||. .|..||||..|.... .
k...feeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
IVMMTKLEERNRVKCDQYWPT--RDQEKYGFIQVTLLDTTELATYTVRSFALV-KN--------------RSMEKREVKQFQFTAWPDHGV-PEHATSVL
|||.|.|.|. . || ||||. ..|..|...||| ... . ...|..... .. .... ..| |.| | ||..|| .|..| .
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLq
AFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
. .. . .. ||.|||||..|.|.| |. .. || | | ||... . .| .. .|.| |||..|.... . .
viddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmyl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1232-1475 | 1e-61 | 203.3 | In-house | 46-292 (297) | alignment | ||
Range on Protein: 1232-1475
Range on HMM: 46-292/297.0
FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANY-CDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQY
| . .. | | |||...|..|||||| |. ||| || | .. ||||||||| .|.||||.||||| . ||..|.||| . .|..|
stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry
WPTRDQEKYGFIQVTLLDTT-ELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVID
|| .| |.. .| |. | |||| | .. | | | || | .||..||| | |.| | .| . . |||||||.|.||||.||.||
wpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilid
SMLERI-KHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
.|.|. | | .|| . || ||. .|.|..|. |. |. | |
lvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1213-1473 | 2.3e-61 | 202.4 | In-house | 20-294 (300) | alignment | ||
Range on Protein: 1213-1473
Range on HMM: 20-294/300.0
GNDAMLFsQEYESIEPGQQ-FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLpGSDYTNANYCDG--YRKQNAYIATQGPLLETMADFWRMVWEQR
.....| .||| | . .. . . ..|. |..|||. .|. |...|| ||| . ..| || |. ||..|||| |. |||.|||||
leegkvf.teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqg
TNTIVMMTKLEERNRVKCDQYWPTR----DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNP
.. |||.|. || . |. .|.| .. ..| .|| ... ... ... | | |.|.| .|.| |||||||| .. | .. .|.|
vqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrr
---------PDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
|..||||||||||| |. | ... ..|....|| .. || || ..||| || |....| .
ktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlik
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1216-1489 | 3e-60 | 198.5 | In-house | 8-280 (283) | alignment | ||
Range on Protein: 1216-1489
Range on HMM: 8-280/283.0
AMLFSQEYESIEPGQQFTwDHSNLETNKPKNRYANVIAYDHSRVILSPMEGlpgsDYTNANYCD---GYRKQNAYIATQGPLLETMADFWRMVWEQRTNT
|| . .. . .. . | . . ||.|||. .....| || | . || || . |.... ||..|.|| .|. |||.||.... .
nklfrevlkrlsvpdlda.diasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekita
IVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSME-KREVKQFQFTAWPDHGVPEHATSVLAFiSRVKSCN-PPDAGP
|||.||| | .|.|| |||| | |.|| ||| . | ..... . | .| | . . . .|. | . | |.. | .|.| ||
ivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkf.nkvislqteskkgP
IVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASGTTEVHARNLYG
||||||.|.|||...| . . .. .. | ||.. |. .| || .||| .|| ..||. | | |.. | .|.
ivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqs
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1508-1765 | 6.6e-60 | 197.4 | In-house | 13-265 (283) | alignment | ||
Range on Protein: 1508-1765
Range on HMM: 13-265/283.0
NEFKRLASQKaQPSRFVSANipANKFKNRLLNIQPYEGNRVCLQPIRGvegsDYINASHID---GYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
. .|||. . ... ||. || ||| .| |.. .|| |.. |||||..| |.| . ||..|.|| .| |||.|..... | |||
evlkrlsvpd.ldadiasad..enkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivm
LSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSR-TIRQFQFTDWPEQGVPKSGEGFIDFiGQVhKTKEQFGQEGPIS
|.||.| |.|| |||| . | | | | |. .| .|. . .| . .|. || | | . .. | .| ... . ..|||
ltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkf.nkv.islqteskkgPiv
VHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||.|.|||.|||..|. .. .. | .||.|..||..| ||. .||| |||.. ....||
vhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1524-1766 | 1.1e-59 | 197.0 | In-house | 38-279 (439) | alignment | ||
Range on Protein: 1524-1766
Range on HMM: 38-279/439.0
VSANIPA---NKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGRekchqYW
. |.. | .. ||| .. ... || || | || | |||| .|.|| . . ||||||| |||.||||...|.... ||||..| | . ||
ciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....yw
PAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDG--QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfGQEGPISVHCSAGVGRTGVFIT
|.. . | .| . ..|.|..| ||| . || . ||. ||... ||.. || .||. . .... . ||. ||||||||||| |.
psdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandk.eeygpvvvhcsagvGrtGtiia
LSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
| . ||... | ||. ||.|| || |||. || | | | || .
ldialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1231-1472 | 2.5e-59 | 195.4 | In-house | 27-274 (287) | alignment | ||
Range on Protein: 1231-1472
Range on HMM: 27-274/287.0
QFTWDHSNLETNKPKNRYANVIAYDHSRVILSpMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQY
.|. .. . |||||.|. .|..||.|| || |||| |||| .|....|.||.|||. |. ||||.|.|.|. ....||. | | || .|
tatfkaaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcyky
WPTRDQE-KYGFIQVTLLDTTELA-TYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRV-----KSCNPPDAGPIVVHCSAGVGRTG
|| |.. . | |.||| . . |.||.. |.. . | | |||... .|||.... | ... |. | . . ..||.|||...|.||.|
wPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsG
AYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
.. . ...| . ||. | || .|. .||. |. .. |||
illatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1518-1764 | 6.4e-59 | 194.0 | In-house | 19-269 (290) | alignment | ||
Range on Protein: 1518-1764
Range on HMM: 19-269/290.0
AQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGvegsDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCH
|. . .|. |.|. .|| ...||. |. |. |||||| .. . . || |||||..|.. ||.|.|||.| .||| |. | .. ||.
asdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikca
QYWPAERS---ARYQ--YFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGR
|||| . . .. . |. .|| . .|..| ..... . ..|.| .| .| ||. |||.| |..|. .| .. . || .|||||.||
qywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGr
TGVFITLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
.| |. . .| .. .. ||. ... || .| ..|| || .| | | ||
sGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1506-1765 | 8e-59 | 193.8 | In-house | 12-276 (287) | alignment | ||
Range on Protein: 1506-1765
Range on HMM: 12-276/287.0
MENEFKRLAS-QKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
...|...| .. . | .|. |. ||| .. |.. .|| | | ||||||| .. .|.. .|.||.|||.| | ||||...|..|. ...
vdkevdalkedsesstatfkaaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvit
LSKLREMGREKCHQYWPAERS-ARY-QYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQV--HKTKE-QFGQE
... | .| ||..||| . | | || . |.| | ... |. ..| ..|... .||..... . |.| |. .| | . . .
mtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasev
GPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||. ||...|.||.|..... |...|. | ||. ..| || .| |.||. |... | | |
GPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvty
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1240-1475 | 2.1e-58 | 192.4 | In-house | 41-280 (288) | alignment | ||
Range on Protein: 1240-1475
Range on HMM: 41-280/288.0
ETNKPKNRYANVIAYDHSRVILSpmegLPGSDYTNANYCDGYRKQ-NAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ--
... |||. ... |||.|| | || || . . . .||||.|| .|..|||.||.||....|||... ||... |.|.|||..
klyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkget
EKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC----NPPDAGPIVVHCSAGVGRTGAYIVIDSML
.|.| ..||| ...|. |. | . | ... ....|. |.|.||..|||. ..|.|. |.|. . . |.||||||||||||.. .. . .
vkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaav
ERIKHE-KTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
. .... .|| | ||.|| .|||..||. | || ||.
relekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1557-1768 | 1.9e-57 | 190.2 | In-house | 2-227 (272) | alignment | ||
Range on Protein: 1557-1768
Range on HMM: 2-227/272.0
EGSDYINASHIDGYRQ---RNAYIATQGPLAETTEDFWRMlWEQNSTIIVMLSKLREMGREKCHQYWP------------AERSARYQYFVVDPMSEYNM
. |.||||....|| . ........||| | .||||. .|.. . ||.| .. |.||.||..||| .. . .| ...| .||...
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
PQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKSGegFIDFIGQVHKtkeqfgqEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVD-------
. |||||. .| |..|.......|||| |||.. ..... .... .||. ||||||..|||... | .|... .| |||
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnl
-MFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGS
....|..|| |||..||||.||.|.|.|.||.| |
yleeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1267-1493 | 2.3e-56 | 186.7 | In-house | 1-242 (272) | alignment | ||
Range on Protein: 1267-1493
Range on HMM: 1-242/272.0
LPGSDYTNANYCDGYRK---QNAYIATQGPLLETMADFWRMvWEQRTNTIVMMTKLEERNRVKCDQYWP------------TRDQEKYGFIQVTLLDTTE
|| |.| ||.. .|| . .......||| | |||||. .|.. .|||.....|||.|.|||.||| . . ||.. |||| ..
lplsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
LATYTVRSFALVKN-RSMEKREVKQFQFTAWPDHGVPEHAtsVLAFISRVKScnppdAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVD--------
| |..| . |.. | ||| ....|.|||||||..| .|.... . . ||..||||||..||| ..... .|... .| ||
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
IYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAvASGTTEVHARNLYGHIQK
... | ||||| ..|||||||.|..||| |. . . ..|.|. | ...
leeaveelraqrpgavqteeqylflyeallel.lrsllsvraeyllaalda
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1530-1764 | 7.9e-55 | 180.7 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 1530-1764
Range on HMM: 2-237/237.0
ANKFKNRLLNIQPYEGNRVCLQPIRGveGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPA-ERSAR
|| ||| ||. |. .|| |. . |||||||....|. . |||.|||| . .|||.|.|... ..||||. | | ..|||.||| .. |
enkiknrygnivaydhsrvvlkgags..gsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YQYFVVDPMSEYNMPQYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERM
| . | . .. .| .| . .. . | | |.||| ||..|||. .. | .. . . . || .||||||||||.|. . .| .
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
RYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
. . .||... |. . .|| ..||.||| | ... ||
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1525-1766 | 9.8e-55 | 180.5 | In-house | 39-236 (392) | alignment | ||
Range on Protein: 1525-1766
Range on HMM: 39-236/392.0
SANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGrekchqywpaer
.|. . |. ||| || ||. .|| |. | . |||.|||.|... . .||||.||| | . .|||||....| | |.|..||.|
vaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd............
saryqyfvvdpmseynmpqyilrefkvtdaRDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVhktKEQFGQEG-PISVHCSAGVGRTGVFITLSVVL
. . ||. ||.||.||...||| .. || .| | .||| |. .||||||||||| |.. |.
..............................kgddartvaqfhftewPdkdvpkhtssllkfikev...kadfGqythpliihcsagvgrtgvvisidsvv
ERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
. . .||.|. | .| .|| ||||..|| | | | || |
ahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1530-1764 | 2.5e-53 | 175.7 | In-house | 6-238 (239) | alignment | ||
Range on Protein: 1530-1764
Range on HMM: 6-238/239.0
ANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSaRY
|| ||| || |. .|| |. . |||||||.. | .||||||| .. .. |||||.|.. .||||. | | ..||||||| | .|
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.ky
QYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVhkTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRY
. | . .||.| | ... . . | . |..|| ||..|||. . . .. ||. . | .|||||||||| |. . .| . .
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki..tkdslpgarpwvihcsagvgrtgaflvidamlrqakk
EGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
. ||.|. || .| .|| |||| .|| | . | ||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1530-1764 | 3.3e-53 | 175.3 | In-house | 7-239 (239) | alignment | ||
Range on Protein: 1530-1764
Range on HMM: 7-239/239.0
ANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSaRY
|| ||| || |. .|| |. . |||||||.. | .||||||| .. .. |||||.|.. .||||. | | ..||||||| | .|
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.ky
QYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVhkTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRY
. | . .||.| | ... . . | . |..|| ||..|||. . . .. ||. . | .|||||||||| |. . .| . .
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki..tkdslpgarpwvihcsagvgrtgaflvidamlrqakk
EGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
. ||.|. || .| .|| |||| .|| | . | ||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1242-1476 | 4e-53 | 175.0 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 1242-1476
Range on HMM: 1-172/182.0
NKPKNRYANVIAYDHSRvilspmeglpGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTkleernrvkCDQYWPtrdqekygf
|..|||| ... ||||| ..|| |||. .|..... .||||||||.|.|||.||..|.. .|||..| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
iqvtlldttelatytvrsfalvknrSMEKREVKQFQFTAWPDHGVPEhATSVLAFISRVKScnppDAGPIVVHCSAGVGRTGAYIVIDSMLERikhekTV
. ..|.. |.... |||||||. ..|.|| .|.. . ||..|||||||||||...... |... |
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gv
DIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVA
... | .| .|. ||.|..||.|.. ||.| .
sleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1558-1759 | 1.4e-51 | 170.0 | In-house | 1-163 (174) | alignment | ||
Range on Protein: 1558-1759
Range on HMM: 1-163/174.0
GSDYINASHIDGYRQRNAYIATQGPLAettedFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAersaryqyfvvdpmseynmpqyilrefkvtdARDG
||||||||..|... . .||.||||| ||.||.|...|..||| ...|.|..||..||| |.
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
QSRTIRQFQFTDWPEQGVPKSGEgFIDFIGQVHKTKEQfGQEGPISVHCSAGVGRTGVFITLSVVLERMRyEGIVDMFQTVKMLRTQRPAMVQTEDQYQF
.|.. |.... || ||| . . ...|. .|.. .. ...||. |||||||||||... . .| ... |. || ...|..||.||| ||||..||.|
lerlgiqylylpwpDhgvpdlsi.llefvkfveealse.dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
CY
.|
ly
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1269-1469 | 1.8e-51 | 169.6 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 1269-1469
Range on HMM: 1-164/174.0
GSDYTNANYCDGYRKQNAYIATQGPLLetmadFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTrdqekygfiqvtlldttelatytvrsfalvkNRSM
|||| ||...|... . .||.|||| ||.|..|.. .|.||.....|....|| .|||. .|.
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
EKREVKQFQFTAWPDHGVPEHATsVLAFISRVKSCNPP-DAGPIVVHCSAGVGRTGAYIVIDSMLERIKhEKTVDIYGHVTCLRAQRNYMVQTEEQYIFI
..|.. |.... |||||||. .. .| |...|... . ||..|||||||||||. .... || ... |..||.. .| || || .||||..||.|.
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl
HE
..
yy
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1531-1766 | 2.3e-51 | 169.3 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 1531-1766
Range on HMM: 1-171/182.0
NKFKNRLLNIQPYEGNRvclqpirgveGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSklremgrekCHQYWPaersaryqy
|. ||| .| ||. .| ..|||||. ..|.. . .||||||| .|..||.|||.|.. |.||.|. ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
fvvdpmseynmpqyilrefkvtdarDGQSRTIRQFQFTDWPEQGVPKsGEGFIDFIGQVHKtkeqfgQEGPISVHCSAGVGRTGVFITLSvvleRMRYEG
. |.. |.... || ||| . ..||| .|.. ..||. |||||||||||... . |.. |
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle......eggpvlVHCsaGvgRtgtlvaay....lmkklg
iVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|.....||..| .|| ||.|..||.|.. |.||.|
.vsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1507-1766 | 1.9e-47 | 157.9 | In-house | 22-280 (314) | alignment | ||
Range on Protein: 1507-1766
Range on HMM: 22-280/314.0
ENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEgNRVCLqPIRGVEGSDYINASHIDGYrqrNAYIATQGPLAETTEDF----------WRML--
. ...|. .. .. |....|. ||| |.|.|.. |||.| | .|.||||||||..||. ...||||||| .| .|| |||
llvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlr
WEQNSTIIVM---------------------LSKLREMGrekchQYWPAERSARYQyfvvdpmSEYNMPQYIlrefkvtdardgqSRTIRQFQFTDWPEQ
...|. .||| | .| . | ...|.. . .. .|.. |.. .|.. .. ...|
gdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.....neptaadlellk.......eelydpelf.............erlgikylripvpDg
GVPkSGEGFIDFIGQVHKTkeqfGQEGPISVHCSAGVGRTGVFITLSVVLERMryeGIvDMFQTVKMLRTQRP-----AMVQTEDQYQFCYHAALEYL
..| . | | .|. ... ..||. |||.||.||||.|... .. .. |. .. ......| .|| .... .||.|...| ||||
sap.lledfdeflefieea....dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleyl
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1227-1473 | 3.7e-47 | 155.4 | In-house | 41-281 (290) | alignment | ||
Range on Protein: 1227-1473
Range on HMM: 41-281/290.0
EPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSpmEGLPGsDYTNANYCDGYRkqNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVK
|.|.. . . .|. |||| .|. | .||||. .| .| || ||| .| . .| |||.| .|. |.|||| .... .|||. .| | . |
lpvqylerkifdkntefkknrykdvvcndktrvilk..dGydG.dyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkak
CDQYWPTRDQEKYGFIQVTLLD---TTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCnppdAGPIVVHCSAGVGRTG
|.||.| .. | | ..|.| ... | . ... . | . .| .. .|||. |. . ..| . .. .||.|||||||.||||
ceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrtG
AYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
... |. |. . . | .|. . | || | || . ||. . |.| .
tfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1238-1474 | 1.3e-46 | 154.1 | In-house | 37-276 (307) | alignment | ||
Range on Protein: 1238-1474
Range on HMM: 37-276/307.0
NLETNKPKNRYANVIAYDHSRVILSpMEGLpGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQE
...| |||| .| . |..|... ..|| ||| ||| | . .|..|||| .|. .|| |. ... ....|. |. | ..||.|||| . .
afsantdknryqdvkcqdkgrivvk.fdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegq
KYGF------IQVTLLDTTELATY--TVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKScnppDAGPIVVHCSAGVGRTGAYIVID
| | | |. | . .|| . .| . . . | ....|.. |||.|||. . . ... |. | |.||||||||||.|. . |
klvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry....dtnpvvvhcsaGvGrsGtivais
SMLER-IKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
. .. |. . |. | ||.||.| .||| ||...| | |
lvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1557-1760 | 3.7e-46 | 152.3 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 1557-1760
Range on HMM: 3-155/172.0
EGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLremgrekchqywpaersaryqyfvvdpmseynmpqyilrefkvTDARD
|||||||||..|.|. . .||||||| .|..||||||.|.. |.||.| .| . ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
GQSRTIRQFQFTDWPEQGVPkSGEGFIDFIGQVHKTKeQFGQEGPISVHCSAGVGRTGVFITLSVVLERMryegivDMFQTVKMLRTQRPAMVQTEDQYQ
. .|.. |.... || .||| . | ...|. .... . ..||. |||||||||||... . .|... .....|...|..|| .||...||.
llerlgiqylylpwpDhgvp.llellleflefidell.alspggpvlVHCsaGvgRtgtlvaaylmllgl......sleeavalvrekRpgavqnpsqyr
FCYH
|.|.
flyy
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1550-1767 | 5.1e-46 | 151.9 | In-house | 3-174 (176) | alignment | ||
Range on Protein: 1550-1767
Range on HMM: 3-174/176.0
LQPIRGVEGSDYINASHIDGYRqrnaYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYqyfvvdpmseynmpqyilref
|... ...|||||. |.|.| .||||||| .|..||..||.|.. |..|.| ...|.|| ||..||| .... .
lrllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.....................
kvtdardgqsrtirQFQFTDWPEQGVPKSgEGFIDFIGQVHKTKEQfGqeGPISVHCSAGVGRTGVFITLSvvleRMRYEGIVDMFQTVKMLRTQRP-AM
|.....||. ||| . | ..... .... .. | ||. ||||||.||||... . ...| ..........| ||| .
..............qylhlpwpDhgvpdl.elllellefirealke.g..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplga
VQTEDQYQFCYHAALEYLG
|||..||.|.|...|..|.
vqtpeQyrflyefellllk
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1268-1469 | 8.2e-46 | 151.2 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 1268-1469
Range on HMM: 3-155/172.0
PGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLeernrvkcdqywptrdqekygfiqvtlldttelatytvrsfalVKNRS
.|||| ||.| |.|.. . .||||||| .|.||||||..|. ..||..|.| .....
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
MEKREVKQFQFTAWPDHGVPeHATSVLAFISRVKS-CNPPDAGPIVVHCSAGVGRTGAYIVIDSMLerikheKTVDIYGHVTCLRAQRNYMVQTEEQYIF
..|.. |.... ||||||| .. .| |.. ... .. . ||..|||||||||||. .... || . .... | .|..|...||...||.|
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
IHE
...
lyy
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1235-1474 | 1.2e-45 | 150.6 | In-house | 26-258 (267) | alignment | ||
Range on Protein: 1235-1474
Range on HMM: 26-258/267.0
DHSNLETNKPKNRYANVIAYDHSRVILSPMEglpgSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNrvkCDQYWPTR
| | |. .||. ... ||..||||. | .| || | .||...||.|.||.|| |..||. .. .|. .||..|| . | ..|| .
sqsiaeknqernrlddnlpyddtrvilrtke....eeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn...irlfwPPk
--DQEKYGFIQVTLLDTTELATYTVRSFALvKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFIsRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSML
. .|| . | | | . .. | | . ..| . . | . | | | |.||.||.||||.|...||||.|
mgqakkyqdltvehslekeendyqiitlel.kfknesahnvtlyyykkwnintnnkpylkplfgi.laknqlengnrPlvvacsdGvGrsGtflvidsql
ERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
||.|.| ..||. . .| || .|.| |.||.||| | |
eraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1267-1473 | 6.5e-45 | 148.3 | In-house | 9-171 (176) | alignment | ||
Range on Protein: 1267-1473
Range on HMM: 9-171/176.0
LPGSDYTNANYCDGYRkqnaYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTrdQEKYGFiqvtlldttelatytvrsfalvknr
...|| |||. .|.| .||||||| .|.|||..|..|.. ...|..|.. | .|.||..||| ||.|.
dldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi.........................
smekrevkQFQFTAWPDHGVPEHaTSVLAFISRVKSCNPPDaGPIVVHCSAGVGRTGAYIVIDsmleRIKHEKTVDIYGHVTCLRAQRN-YMVQTEEQYI
|.... |||||||.. . .| .. .... . ||..||||||.||||...... ...|| .... . .|.|| ..|||.|||
........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyr
FIHEALYE
|..|....
flyefell
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1278-1469 | 6.2e-44 | 144.7 | In-house | 2-144 (152) | alignment | ||
Range on Protein: 1278-1469
Range on HMM: 2-144/152.0
CDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWptrdqekygfiqvtlldttelatytvrsfalvknrsmekrevkQFQ
|||......||||||. .|.||||||..|. .||||.|.|.|....||.||. |..
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qyl
FTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLerikheKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHE
.. |||||||... .| .. .. .. . ||..|||||||||||...... || . |... | .|..|...|....|..|..|
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1232-1476 | 3.1e-43 | 144.0 | In-house | 36-281 (314) | alignment | ||
Range on Protein: 1232-1476
Range on HMM: 36-281/314.0
FTWDHSNLETNKPKNRYANVIAYDhSRVILsPMEGLPGSDYTNANYCDGYrkqNAYIATQGPLLETMADF----------WRMV--WEQRTNTIVM----
.|. ..|. |. |||| ... .| .|||| | .. |||| ||.| ||. ...||||||| .|. || |||| ..... .|||
ltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrde
-----------------MTKLEERNrvkcdQYWPTRDQEKYGfiqvtlldttelatytvrsfA-------LvknrsmeKREVKQFQFTAWPDHGVPeHAT
..| ... ... .|.| . . .|.. .. . .||...|
vladelsrLdaAlgKtpllildgng.....neptaadlellk....................eelydpelf.......erlgikylripvpDgsap.lle
SVLAFISRVKSCnpPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHeKTVDIYGHvtcLRAQRN-----YMVQTEEQYIFIHEALYEAVA
...|. .... .. ||..|||.||.|||| ..|.. .. . . ... . .|..| .... |||.||.|||.|..
dfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealed...vrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1504-1766 | 9.2e-43 | 141.4 | In-house | 16-277 (307) | alignment | ||
Range on Protein: 1504-1766
Range on HMM: 16-277/307.0
TGMENEFKRLAsqKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpIRGVeGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
. . .||. || | .| . || ||| ... . .|. .. . |. |||| | .. . . .|..|||| .| .|| | ... ..
qalvdefrvla..kktpegvtveafsantdknryqdvkcqdkgrivvk.fdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvi
MLSKLREMGREKCHQYWPAERSARYQYFVV-DPMSEYNMPQYILR----EFKVTD---ARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHktkeq
|| |. |... ||.||||.|. . . . .| |. | .||. ..||||...|...||..|||. . |... |.
mlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr.....
fGQEGPISVHCSAGVGRTGVFITLSVVLERM-RYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
... |. |||||||||.| ...|.| ..| . . || . |. ||.||. .||| || . . |||.
.ydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1507-1765 | 3e-42 | 139.5 | In-house | 9-258 (267) | alignment | ||
Range on Protein: 1507-1765
Range on HMM: 9-258/267.0
ENEFKRLASQKAQPSRfVSANIP-ANKFKNRLLNIQPYEGNRVCLQpirGVEgSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
|.||. . . |. .| |. |. .||| . ||. .|| |. | .|||||...||...||.|.||.|| | ||. .. .|. ..||.|
ekefelikkisdtsst.isqsiaeknqernrlddnlpyddtrvilr...tke.eeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivll
SKlreMGREKCHQYWPAE--RSARYQYFVVDPMSEYNMPQY--ILREFKVtdaRDGQSRTIRQFQFTDWPEQGVPKSgeGFIDFIGQVHKTKEQFGqEGP
| . .. ...|| . .. .|| ..|. | . .| | |.|. .. .. . . . | . | . ..| . | . . | . |
tk...vftdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkf...knesahnvtlyyykkwnintnnkp..ylkplfgilaknqleng.nrP
ISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
. |.||.||||.| |... |||.. ||..|.|. .. .| ||...|.| ..| .... ||
lvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1567-1759 | 3.7e-42 | 138.9 | In-house | 2-143 (152) | alignment | ||
Range on Protein: 1567-1759
Range on HMM: 2-143/152.0
IDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWpaersaryqyfvvdpmseynmpqyilrefkvtdardgqsrtirQFQ
||||.. ...||||||. .|..||||||.|.. |.|||| .| |.|..||.||. |..
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qyl
FTDWPEQGVPKSGEGFIDFIGQVHKTkeQFGQEGPISVHCSAGVGRTGVFITLSVVLermryeGIVDMFQTVKMLRTQRPAMVQTEDQYQFCY
.. || |||.. . ..... ..| . ..||. |||||||||||... . .| |.....|...|..|| .|....|..|.|
hlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1238-1437 | 6.2e-42 | 138.8 | In-house | 43-258 (418) | alignment | ||
Range on Protein: 1238-1437
Range on HMM: 43-258/418.0
NLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGY-RKQnaYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTR--
. . | ||||.|.. .|.|| | .. |||| |||| || || .|.||||| .|.|||||||||.| |||... | |.|||.||| .
dkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkq..fictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqig
---------DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFI---S-RVKSCNPP--DAGPIVVHCSAGV
.| .| | |.. . . . . | |.. |.|. |||| .|.|. . .. . | . | ||.|||||||
geqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagv
GRTGAYIVIDSMLERIKH
||||.. |.... |
grtgtfctavimmkkldh
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1240-1472 | 3.2e-41 | 135.9 | In-house | 53-286 (305) | alignment | ||
Range on Protein: 1240-1472
Range on HMM: 53-286/305.0
ETNKPKNRYANVIAYDHSRVILSPMEglpGSDYTNANYCDGY-RKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEK
. .. ||||..| . |.| | |. ||| ||| .. .|..|||| .|. .|| || ... . |||. | | ..|| ||||. ||
diaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgek
YGFIQVTLLDTTELATYTVR----SFAL--VKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRTGAYIVIDSML
. ... . | .| . .| |...|.| ||| ||| . | ..| .. . |||||||||.||||. . |. .|
lelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk....vpivvhcsagigrtgtivaieyil
ERIKHEKTVD-IYGHVTCLRAQRNYMVQTEEQYIFIHEALY
|.| .| . . | .|| || . .|.. ||.||| .
ekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvml
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1242-1472 | 5.7e-40 | 131.9 | In-house | 48-284 (305) | alignment | ||
Range on Protein: 1242-1472
Range on HMM: 48-284/305.0
NKPKNRYANVIAYDHSRVILspmEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGF
.. |||| .| |. || | || .| ||| . . .| || || .| |||| | .... ..| |. .| |. || .|....|... |
eagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlef
------IQVTLlDTTELATYTVRSFAL-------VKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKscnpPDAGPIVVHCSAGVGRTGAYIVI
|.| . .... .. . | .. ..| |... . ||| ||| ...| .. . . | ||||||||||.||||. ...
eekgqkisvkf.essvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekar....pskgpivvhcsagigrtgsvvml
DSMLERIKHEKTVDIYGH-VTCLRAQRNYMVQTEEQYIFIHEALY
. .|... . .. . . .| ||| .||..||.|.|. .
eyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvil
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1542-1765 | 1.9e-39 | 130.5 | In-house | 1-170 (178) | alignment | ||
Range on Protein: 1542-1765
Range on HMM: 1-170/178.0
PYEGNRVCLQPIRGVEGSDYINASHIDGYrqrnAYIATQGPlaettEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSaryqyfvvdpmseynm
|....||.|....|.|.|||||||.|... |.....| .|....|.|.. | ||.|.. |.|..||..||| | .
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
pqyilrefkvtdardgqsrtiRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPISVHCSAGVGRTGVFITLSVVLERmryeGIvDMFQTVKML
|.... .| ||| . | | .|. ... . ..||. |||||||||.|... . .... |. .... ....
.....................iqylhipipDhgvpdllehflefvefieeald..ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielv
RTQRPaMVQTEDQYQFCYHAALEY
| .|| .|....|....| .|..
rerRp.ivpnpgqlrqLyefelrl
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1558-1762 | 2.8e-39 | 129.4 | In-house | 2-149 (151) | alignment | ||
Range on Protein: 1558-1762
Range on HMM: 2-149/151.0
GSDYINASHIDGYrqrnaYIATQGPlaetTEDFWRMLWEQNSTIIVMLSKLREMGreKCHQYWPAERsaryqyfvvdpmseynmpqyilrefkvtdardg
|||||.| ..|. .....|| ..||...|.|.. . ||.| .. |.| .|..|.|..
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
qsRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKtkeqfGQEGPISVHCSAGVGRTGVFITLSVVLERmryegiVDMFQTVKMLRTQRPAMVQTEDQYQF
.........|||..|.| | . ...|. .. . ..||. ||||||.||||... | .|.. |.........| .|| .||...|..|
..ievlhipildwpdpglplsfdavleflellld.....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
CYHAA
...|
qlfal
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1238-1473 | 1.2e-38 | 127.4 | In-house | 33-267 (281) | alignment | ||
Range on Protein: 1238-1473
Range on HMM: 33-267/281.0
NLETNKPKNRYANVIAYDHSRVILSP-MEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ
| |. ||||.|. . | ||| | | .|| ||| . || |||| || ||||||.|.. | .|||. .. | || || .|.| .
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
EKYGFI--QVTLLDTTELATYtvRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCnppdAGPIVVHCSAGVGRTGAYIVIDSMLER
| |. |.| . . | | | . .. . ||| ||| . .| . .... . | |.||||||||.|. . .. |.
cclqfdklsvsyedstvnksl..vttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirar....stppvihcsagvgrsgtlmaveialqs
IKHEKT-VDIYGHVTCLRA-QRNYMVQTEEQYIFIHEALYE
|. | || |. || | ||| .||..| . | .
ihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1504-1726 | 1.5e-38 | 127.7 | In-house | 21-256 (418) | alignment | ||
Range on Protein: 1504-1726
Range on HMM: 21-256/418.0
TGMENEFkRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRnAYIATQGPLAETTEDFWRMLWEQNSTIIV
...|| || . || . | ||| || | . || |. |. |||||||| .||| . .|.||||| .| |||||.||. |||
hkikeef.rlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpntiadfwrmvwenrcriiv
MLSKLREMGREKCHQYWPAERSArYQYFVVDP----MSEY-----NMPQYILREFKV---TDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHK
|||. | | || .||| . |. . . | .. | || . .|..| | |.|. ||.. .| . | ... . .
mlsresencrikcdrywpeqigg.eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitn
TKEQF----GQEGPISVHCSAGVGRTGVFITLSVVLERM
..| .. || ||||||||||| | | ......
rqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkl
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1223-1484 | 2e-38 | 126.7 | In-house | 33-298 (310) | alignment | ||
Range on Protein: 1223-1484
Range on HMM: 33-298/310.0
YESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSpMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEER
| .. |. . . . . ||||..|. | ||| | .. || ||| ....| .|||| |. |||||....|...|... | |
yrkldakqdssltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgee
NRVKCDQYWPTRD-QEKYGFIQVTLLDT-------TELATYTVRSFALVKNRS--MEKREVKQFQFTAWPDHGVPEHATSVLAfiSRVKScnPPDAGPIV
| || |||. | || |.|| | .|| | | .. ... |. .. ||| |||. . |. . || |
grpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp..qrlla..qvrhgpcv
VHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALyEAVASGTTEVHA
||||||..|... . .. ...... . ||. .| |. .| .||| ||..|. . | | |||
vhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvr.iifargetevae
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1506-1765 | 5e-38 | 125.3 | In-house | 13-268 (281) | alignment | ||
Range on Protein: 1506-1765
Range on HMM: 13-268/281.0
MENEFKRLASQkaQPSRFV-SANIPANKFKNRLLNIQPYEGNRVCLQP-IRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
...|| | . || .. | | |. ||| ||| . || |. . . .||| | .| . || |||| || |||||.|..|.| ||
fkqefsnlpgd..ppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaiv
MLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKtkeqfgQEGPIS
|| .. | |||| .|.| . . |. . | . | .. . .|..| | .. . .||. ||.| | .. . ... . |
mlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira......rstppv
VHCSAGVGRTGVFITLSVVLERMRY-EGIVDMFQTVKMLR-TQRPAMVQTEDQYQFCYHAALEY
.||||||||.| .... . |. .. . |. | | || | | | ||| .|| . .. |..
ihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
|||||||||
PTPc_DSPc_SM00012 | 1661-1764 | 4.3e-37 | 121.9 | In-house | 1-105 (105) | alignment | |||
Range on Protein: 1661-1764
Range on HMM: 1-105/105.0
TIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYE-GIVDMFQTVKMLRTQRPAMVQTEDQYQFCY
|......|.||..|||.... ..... .|.| |.. ....|. |||||||||||.|..|...|.....| . ||.||.||.||.||| |||||.||.|.|
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
HAALE
.| ||
ralle
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1269-1473 | 5.5e-37 | 122.0 | In-house | 2-151 (151) | alignment | ||
Range on Protein: 1269-1473
Range on HMM: 2-151/151.0
GSDYTNANYCDGYrkqnaYIATQGPlletMADFWRMVWEQRTNTIVMMTKLEERNrvKCDQYWPTRDqekygfiqvtlldttelatytvrsfalvknrsm
|||.|..| .|. .....|| .|||.....|. .|||.....|||. .| .|.| .
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
ekREVKQFQFTAWPDHGVPEHATSVLAFISRVKScnpPDAGPIVVHCSAGVGRTGAYIVIDSMLERikhektVDIYGHVTCLRAQRNYMVQTEEQYIFIH
.||...... |||.|.|.. .||.|.. . . .. ||..||||||.||||. .... ||.. |... . .|..| ..||...|..|..
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
EALYE
||.|
falle
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1254-1471 | 6.2e-37 | 122.3 | In-house | 2-167 (178) | alignment | ||
Range on Protein: 1254-1471
Range on HMM: 2-167/178.0
YDHSRVILSPMEGLPGSDYTNANYCDGYrkqnAYIATQGPlletmADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQekygfiqvtlldttela
.|..||.||..|||..|||.||.. ... |.....| ||......|. ..||..|. |....|||.|||..
ldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................
tytvrsfalvknrsmekrevKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERikhekTVDIYGHVTCLRAQ
|.... .||||||. .|.|. .... ... ||..|||||||||.|. .... |... .... . .|..
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RNyMVQTEEQYIFIHEAL
|. .|....|. ...|
Rp.ivpnpgqlrqLyefe
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1533-1767 | 6.9e-36 | 118.4 | In-house | 58-284 (290) | alignment | ||
Range on Protein: 1533-1767
Range on HMM: 58-284/290.0
FKNRLLNIQPYEGNRVCLQpiRGVEGsDYINASHIDGYRqrNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARY---Q
||| .. . || |. | .| ||. | ...| . .| |||.|..|. |.|||. ... . |||| .| | |. ||.||.| . .
kknrykdvvcndktrvilk..dGydG.dyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
YFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTkeqfgqEGPISVHCSAGVGRTGVFITLSVVLERMRYE
. |. ... . . |.. . | | .|.. .. .. ||.. |..| .. . . |. ||. ||||||.|||| |... | |. .
itvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka......sGpvvvhcsaGiGrtGtfvaievglqilldG
GIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLG
.|. ..|. || | . || . || .. |..
keldlldlvralrnsrlnsvqvdiqylalveilldlGk
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1238-1474 | 1.2e-35 | 117.8 | In-house | 31-269 (285) | alignment | ||
Range on Protein: 1238-1474
Range on HMM: 31-269/285.0
NLETNKPKNRYANVIAYDHSRVILSPMEglpgSDYTNANYCDG-YRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ
|.| ||||.| . . .||.| . || |.. . |..||.||||| ||..|||.|..... ..|. | | || |.| .
ayeanpdlnryadvrcieetrvvlknhd....rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklg
E--KYGFIQVTLLDTTELATY--TVRSFALV--KNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDaGPIVVHCSAGVGRTGAYIVIDS
| |.| ..|| . | | . ..... .. | | ... | |||. || | .. . || || . ||.|||||||||| ... ||
evvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpke.kpicvhcsagvgrtatfvgidy
MLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
|| . ... | .|| | ||. |..|.. | |
atirimenpniemldivremramrfqavqshmqflflyvvlmey
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1240-1403 | 2.5e-35 | 116.8 | In-house | 31-196 (297) | alignment | ||
Range on Protein: 1240-1403
Range on HMM: 31-196/297.0
ETNKPKNRYANVIAYDHSRVILspMEGLPGSDYTNANYCDG--YRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQE
.. |||| ...|.| .|| | . . ...|| ||.| .. || .|||| .|. |||..|.|| ..|||..||.| | || ||| .||
nsslrknryrdilatddtrvkl..lrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqe
KY--GFIQVTLLDTTE--LATYTVRSFALVKNrsMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC
. | . | | .| . . . |. |.| |. || .||||||| . | ..| ||
rlkagdvvveflsstsdefdrviltelqliyr..sesrvvrhvqflswpdhGvpsdledlvrfqaqvcsc
|
|||||||||
PTPc_DSPc_SM00012 | 1373-1472 | 7.5e-35 | 114.7 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 1373-1472
Range on HMM: 2-104/105.0
VKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDA--GPIVVHCSAGVGRTGAYIVIDSMLERIKHE-KTVDIYGHVTCLRAQRNYMVQTEEQYIFIHE
||....|.||||||||...|.| .. ||... . .|.|||||||||||| ....| .|.....| |.|||. | || ||. ||||||||.|...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
ALY
||
all
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1241-1476 | 1.6e-34 | 114.3 | In-house | 42-272 (288) | alignment | ||
Range on Protein: 1241-1476
Range on HMM: 42-272/288.0
TNKPKNRYANVIAYDHSRVILSpmegLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYG
.| ..|| |. | .|| || | .|| . .. | .| || |. .|.|. |. . |||...| |. . | ..|.|.. ||
anptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
FIQV-TLLDTTELATYTVRSFALVKNR-SMEKRE-VKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRTGAYIVIDSMLERIKH
. .. | . . .|... .|.. ||. . |.|.|||| | | .. ..||.. |||||.||||||||. |.| .|| ..
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslq....kPivvhssaGvGrtgtlililialeslrl
EKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVA
. . | .. ||..| .||| ||...| ..| ..
ddflgirsllaklreerfkaiqtemqylyvhrcvleell
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1508-1689 | 1.6e-34 | 114.1 | In-house | 11-193 (297) | alignment | ||
Range on Protein: 1508-1689
Range on HMM: 11-193/297.0
NEFKRLaSQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpiRGVEGSDYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
.| | ..|.. | ||. .. ||| .| .. .|| |. |.. ..||||| .. . || .|||| .| .|||....||. .|||.
aekdll.ldeargesfssakrnsslrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmv
SKLREMGREKCHQYWPAERSARY--QYFVVDPMSEYN--MPQYILREFKVTDArdGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQV
.||.| ||.|| ||| | .||. .|.. . || |... .|| .| || ||. ||| | | ||
aklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyr..sesrvvrhvqflswpdhGvpsdledlvrfqaqv
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1531-1766 | 1.2e-33 | 111.1 | In-house | 55-289 (305) | alignment | ||
Range on Protein: 1531-1766
Range on HMM: 55-289/305.0
NKFKNRLLNIQPYEGNRVCLQPIRgveGSDYINASHIDGYR-QRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARY-
.. ||| .. . . | |. |||| | .. . .|..|||| .| ..|| |. ... |||| | |.|. || ||||| . .
aitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
--QYFVVDPMSEYNmPQYILREFKVTD----ARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHktkeqfGQEGPISVHCSAGVGRTGVFITLSVV
||. .| . | | ..| .|. ..|..|.|.||..||| .... . | . || ||||||.|||| ... .
lksgivvenvsgsk.pmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair......gskvpivvhcsagigrtgtivaieyi
LERMRY-EGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
||.. | . || || || .|.. || | . |.|.
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1562-1756 | 1.9e-32 | 107.2 | In-house | 78-271 (301) | alignment | ||
Range on Protein: 1562-1756
Range on HMM: 78-271/301.0
INASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQ--YFVVDP-MSEYNM-PQYILREFKVTDAR-D
| | |. . . .||||||| .|.|||| || . ||||.. .| |||..| | . | . . | . .|. . . . |...|.|. .
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
GQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgqegPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQ
..||. .|...|...||||| |.. | |... || ||||||.||. ||. .. .. . ... ...| || .| |||. |
fatrtvthyqysewtdrgvPkshaelfdlmelvkksek......PivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqly
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1274-1467 | 1.5e-31 | 104.3 | In-house | 79-273 (301) | alignment | ||
Range on Protein: 1274-1467
Range on HMM: 79-273/301.0
NANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEK--YGFIQVTLLDTTELATYTV--RSFALVK-NRSM
||. . . . .||||||| .|. ||| |. ..|||... |.. ||..| |.. .|| | .... .. . . |.. .. . .
hanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkf
EKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFI
. | | .|.. |.|.|||. . . .. || . |||||||||.||. |.| . . ... ..|... . || .| |||..| ..
atrtvthyqysewtdrgvPkshaelfdlmelvkkse....kPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywm
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1241-1402 | 3.8e-31 | 102.9 | In-house | 27-192 (319) | alignment | ||
Range on Protein: 1241-1402
Range on HMM: 27-192/319.0
TNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRD----
| |.|.|..||. ..||.| . . . | .|.| ||.. .| |||.| .| .. .||||.||||.. .|| .|.| | .| .|.||..
tskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldn
QEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFtAWPDHGVPEHATSVLAFISRVKS
.. || |.||| . | . .. | . | ||. . . |.. .|| . ....| . .|.|
tslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1528-1766 | 4.5e-31 | 102.9 | In-house | 32-270 (285) | alignment | ||
Range on Protein: 1528-1766
Range on HMM: 32-270/285.0
IPANKFKNRLLNIQPYEGNRVCLQPirgvEGSDYINASHIDG-YRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERS-
|| || ... | || |. ||| || . .....||.||||| || |||.|..... . ..|| | | | ||| |.| .
yeanpdlnryadvrcieetrvvlkn....hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
----ARYQYFVvDPMSEYNMPQYILREFKVTDARDGQSRTI--RQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqfGQEGPISVHCSAGVGRTGVFITL
.|. . | . || . |... | | . . | ||.| |. .|.. |.| . .| || |||||||||| |. .
vvkfgkyeitl.teckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvn...pkekpicvhcsagvgrtatfvgi
SVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|. . ..|.. |. .|. | ||. |. | | .||.
dyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1530-1766 | 1e-30 | 101.6 | In-house | 47-287 (305) | alignment | ||
Range on Protein: 1530-1766
Range on HMM: 47-287/305.0
ANKFKNRLLNIQPYEGNRVCLQPirgVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQ
.. ||| .. . ||| |.. .|| | .. . . .| || || .| ||| | .... | || .| | | .||..|.... .
qeagknrykdvgcldnnrvkleg...pwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvle
Y------FVVDPMSEYNMPQY------ILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqfgqeGPISVHCSAGVGRTGVFI
. .| | .. . . | . ...| . .. . |||..||| . .... . .| ||| ||||||.|||| .
feekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpsk......gpivvhcsagigrtgsvv
TLSVVLERMRYEGIVDM-FQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
| .|... |.. . .. .| || .||..|| | . |.|.
mleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1243-1478 | 2.9e-29 | 96.7 | In-house | 44-279 (312) | alignment | ||
Range on Protein: 1243-1478
Range on HMM: 44-279/312.0
KPKNRYANVIAYDHSRVILSPMEGLpgsdYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPtrdqEKYGFI
| ||| |. .| | |. | . | ||. | . ...||||| .| . ||... . .|.... . | || .| . ||.
kdlnrypniqcwdrgrftlagdenf....yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyis....divgfv
QV-----TLLDTTE-------LATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKScnppDAGPIVVHCSAGVGRTGAYIVIDS
.. || | | . .| . . .. ....|...|||||.|. . | ..| || | |.. ||||||||||. ..|.|
dledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkk....dkkpviahcsagvgrtgtlalies
MLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASG
|. ..| . .. || .| |.. ||.. .. | . |
miaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflysk
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1505-1766 | 4.8e-29 | 96.3 | In-house | 20-271 (288) | alignment | ||
Range on Protein: 1505-1766
Range on HMM: 20-271/288.0
GMENEFKRlaSQKAQPSRFVSANIpANKFKNRLLNIQPYEGNRVCLQpirgvEGSD-YINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
|.. |.. | . . . ... | || ..| |. . || |. . .| ||.| . . .. | .| || | | .|.|| |.. ||
glkkeyrd..spneasidiidsfi.anptrdryenlprcditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyiv
MLSKLREMGREKCHQYWPAER--SARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRT-IRQFQFTDWPEQGVPKSGEGFIDFIGQVhktkeqFGQEG
||..| | |.|| .|.| . .||.. . . ... . ... . . |. . ... . .|...|||.. .. .. . .
mlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl......kslqk
PISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|| ||.|||||||| .| ..|| .| . . . . .. || .| .||| || . . ||.|
PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1367-1509 | 4.9e-28 | 92.6 | In-house | 85-228 (440) | alignment | ||
Range on Protein: 1367-1509
Range on HMM: 85-228/440.0
SMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKS-CNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYI
..| | .||... .|||.|||. | || .| |. . ||..||||||.|||| |..||.| |. .||. . ..| .| |||| |||
giesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqya
FIHEALYEAVASGTTEVHARNLYGHIQKLTALEPGETITGMENE
|.|||. |.. .| | . .. ..... .| . ...|
fvheavlegllcgdtliledditerveqiqwpnphtdksplqqe
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1283-1468 | 6.9e-28 | 92.2 | In-house | 3-197 (199) | alignment | ||
Range on Protein: 1283-1468
Range on HMM: 3-197/199.0
KQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ--EKYGFIQVTLLDTTELATYTVRSFALVKNRSM--EKREVKQFQF
| ||||| || |||||||.|||| . |||. . . . |||| . ||| . || | . ||. .. |..| . ||. ..||
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
TAWPDHGVPEHATSVLA-FISR--VKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKT--VDIYGHVTCLRAQRNYMVQTEEQYIFIH
|.| .. |. | | || | . |..|||| | | || .. .| . . || ||.. || | .. . ..| ||.
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1284-1468 | 1.4e-27 | 91.2 | In-house | 3-196 (198) | alignment | ||
Range on Protein: 1284-1468
Range on HMM: 3-196/198.0
QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ--EKYGFIQVTLLDTTELATYTVRSFALVKNRSM--EKREVKQFQFT
| ||||| || ||.||||.|||| . |||. . . . |||| . ||| . || | . ||. .. |..| . ||. ..|||
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
AWPDHGVPEHATSVLA-FISR--VKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKT--VDIYGHVTCLRAQRNYMVQTEEQYIFIH
.| .. |. | | || | . |..|||| | | || .. .| . . || ||.. || | .. . ..| ||.
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1529-1694 | 2.9e-27 | 90.2 | In-house | 26-195 (319) | alignment | ||
Range on Protein: 1529-1694
Range on HMM: 26-195/319.0
PANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERS--
.. | |.|..|. | || || | . . |..||.. ||.. .| |||.| .| ... ||||..|||.| .|| |..| | | ..| .|.|.. .
vtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
--ARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFtDWPEQGVPKSGEGFIDFIGQVHKTKE
| . | .|.. . . . .|| . . . .|.| .|| . . .| . .|... .
ntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrsslk
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1503-1760 | 7.7e-27 | 88.7 | In-house | 26-284 (310) | alignment | ||
Range on Protein: 1503-1760
Range on HMM: 26-284/310.0
ITGMENEFKRLASQKAqPSrFVSANIPANKFKNRLLNIQPYEGNRVCLQpIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTII
| |. .....| ... .| . . ||| .. . || |. | ||| | .. |...| .|||| | |||||.... . |
ieglvkqyrkldakqd.ss.ltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesi
VMLSKLREMGREKCHQYWPAER-SARYQYFVVDPMSEYNMpQYILREFKVTDA-----RDGQSRTIR-----QFQFTDWPEQGVPKSGegfIDFIGQVHK
..| | | || || |||. . | | .|| .. . .. || | | .. .. .||..||| . |
lllckvgeegrpkcvgywpslgvtetygcirvtnlsesse.efeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdek...chtvpqrll
TkeQfGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYH
. | . || ||||||..|..| ..| . ..... ||. . . |. .| .||| || . .
a..q.vrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidr
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1232-1471 | 8.6e-27 | 88.6 | In-house | 30-266 (307) | alignment | ||
Range on Protein: 1232-1471
Range on HMM: 30-266/307.0
FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRvkCDQYW
. .. . |. | | | | ||| | .| |. ||. .| | .| .| || .|. ||||||.... . |||.| | .| |. ||
islttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkeser..ceyyw
PTRDQEKYGF----IQVTLLDTTE--LATYTVRSFALVKNRsMEKREVKQFQFtawpDHGVPEHATSVLAFISRVKSCnppdAGPIVVHCSAGVGRTGAY
| ... . .... |. . ..| . || |.| .. .| | . | | . ... . |.||.. || ....
pkaesdslvtvpGslrienlkvdskadplfrvtklklvGgd.deerflehwqg....dvnnssdvysplrvlrklrnl....skpvvvqdilGvskaatl
IVIDSMLERIKHEKT--VDIYGHVTCLRAQRNYMVQTEEQYIFIHEAL
. |. | . . . | || .|.. |.. .|.|.. .
vaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1345-1471 | 1e-26 | 88.7 | In-house | 18-139 (145) | alignment | ||
Range on Protein: 1345-1471
Range on HMM: 18-139/145.0
TLLDTTELATYTVRS-FALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDaGPIVVHCSAGVGRTGAYIVIDSMLErikheKTVDI
| || .|. . .. . | ... ..|.. |.... |||||||. . .|.|. .... . . ||..|||||||||||...... ||. . |..
taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsl
YGHVTCLRAQRNYMVQTEEQYIFIHEAL
. . .|.|| ..|....|..|..|..
eealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1573-1760 | 1.8e-26 | 87.5 | In-house | 4-198 (199) | alignment | ||
Range on Protein: 1573-1760
Range on HMM: 4-198/199.0
RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSAR--YQYFVVDPMSEYNMPQYILREFKVTDAR--DGQSRTIRQFQFT
. ||||| || || |||.|.|| | |||. . |||. |. | . | . |.| . . .|. .| | ..|||
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
DWPEQGVPKSGeGFIDFIG---QVHKTKEQfGQEGPISVHCSAGVGRTGVFITLSVVLER--MRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYH
| |. |. |. |. .| | || .. |. |||| | | ||||..| . . .||.|. | || | .. . ..|.| |
swkekttpnva.lfvgfvvasrevskkyeq.ekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1574-1760 | 2e-26 | 87.4 | In-house | 4-197 (198) | alignment | ||
Range on Protein: 1574-1760
Range on HMM: 4-197/198.0
NAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSAR--YQYFVVDPMSEYNMPQYILREFKVTDAR--DGQSRTIRQFQFTD
||||| || || |||.|.|| | |||. . |||. |. | . | . |.| . . .|. .| | ..|||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPEQGVPKSGeGFIDFIG---QVHKTKEQfGQEGPISVHCSAGVGRTGVFITLSVVLER--MRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYH
| |. |. |. |. .| | || .. |. |||| | | ||||..| . . .||.|. | || | .. . ..|.| |
wkekttpnva.lfvgfvvasrevskkyeq.ekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1355-1469 | 7e-26 | 86.1 | In-house | 31-139 (144) | alignment | ||
Range on Protein: 1355-1469
Range on HMM: 31-139/144.0
YTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDaGPIVVHCSAGVGRTGAYIVIDSMLerikHEKtVDIYGHVTCLRAQR
.|| ... ..||. |.... |||||||.... .|.|. .... ... ||..|||||||||||...... |. ... .... . .|..|
ttvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrr
NYMVQTEEQYIFIHE
..|....|..|..|
pgavpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1283-1466 | 1.4e-25 | 84.8 | In-house | 33-212 (255) | alignment | ||
Range on Protein: 1283-1466
Range on HMM: 33-212/255.0
KQNAYIAtqgplleTMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSM--EKREVKQFQFTA
..| |. |.. |.... ..|...||.. ..| ...||..|.|. .|| . .|.. | | .| .. . . . ..|| ....
rknlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykG
WPDHGVPEHATSVLAFISRVKscnppDAGPIVVHCSAGVGRTGAYIVIDSMLE----RIKHEKTVDI--YGHVTCLRAQRNYMVQTEEQYIF
|... || | .| . |. |. ..|||||.|.||. |....... .. .||.. .. || .|. ..| | |
WieknaPelareilnilkvvr.....dsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlaf
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1650-1765 | 7.7e-25 | 82.7 | In-house | 35-142 (145) | alignment | ||
Range on Protein: 1650-1765
Range on HMM: 35-142/145.0
KVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfgqEGPISVHCSAGVGRTGVFItlsvVLERMRYEGiVDMFQTVKMLRTQRPAMV
.|. ... .|.. |.....|| ||| . | ...|. .... .. .||. |||||||||||... .. |...| |.........|.||| .|
nltselellerlgiqylylpwpDhgvpdllellleflefieealke...ggpvlVHCsaGvgRtgtlv....aaylmlllg.vsleealelvrsqrpgav
QTEDQYQFCYHAALEY
....|..|.| . ||.
pnpgqlrflyefelel
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1283-1467 | 4e-24 | 79.9 | In-house | 36-219 (263) | alignment | ||
Range on Protein: 1283-1467
Range on HMM: 36-219/263.0
KQNAYIAtqgpLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRS--MEKREVKQFQFTA
..| |. |..|.. |.... ..|...||.. .| ...||..|.|. || . .|.. | ... |... . . ..||.....
rknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykg
WPDHGVPEHATSVLAFISRVKscnppDAGPIVVHCSAGVGRTGAYIVIDSM----LERIKHEKTVDI--YGHVTCLRAQRNYMVQTEEQYIFI
|... || | ..| . .. . ..|||||.|.||. |. |.... . .. .||.. .. || .|. ..| | |
Wiekndpelareilnilkvar.....nskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafs
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1502-1763 | 5.2e-24 | 79.5 | In-house | 12-267 (307) | alignment | ||
Range on Protein: 1502-1763
Range on HMM: 12-267/307.0
TITGMENEFKRLaSQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTI
. ..| .. | . .. . | |. | | .. . || |. || |.| | ...| | .| .| || .| .|||||.....
ivqelerrlevl.eesvdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqy
IVMLSKLREMgrEKCHQYWPAERSARYQY----FVVDPMSEYNMPQYIlreFKVTDARD-GQSrtiRQFQFTDWPEQGVPKSGEGFIDFigQVHKTKEQF
||||. .| |.|. ||| | .. . .. . .. .. . |.|| . | .. .| . . | .|.. . . .| . .
ivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadpl...frvtklklvGgd...deerflehwqgdvnnssdvyspl..rvlrklrnl
GQegPISVHCSAGVGRTGVFITLSVVLERMRYEGIV--DMFQTVKMLRTQRPAMVQTEDQYQFCYHAAL
. |. |.. || ........ . | . |. . ..|..|| .|. |.. .| | | |
sk..pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1652-1760 | 6.1e-23 | 76.6 | In-house | 48-139 (144) | alignment | ||
Range on Protein: 1652-1760
Range on HMM: 48-139/144.0
TdardgqsrtIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgQEGPISVHCSAGVGRTGVFITLSvvleRMRYEGiVDMFQTVKMLRTQRPAMVQT
. . |.....|| ||| . | ...|. ... | ..||. |||||||||||..... .|...| ..........|..|| .|..
e.........giqylhlpwpDhgvpdllellleflefieeale...eggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavpn
EDQYQFCYH
..|..|..
pgqlrfLle
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1658-1767 | 6.8e-23 | 75.7 | In-house | 87-195 (440) | alignment | ||
Range on Protein: 1658-1767
Range on HMM: 87-195/440.0
QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQF
.|||..|... ||..|||| . .| .| ...|. | .||. ||||||.||||| |.. .| . .|.| .. .| .|| |||| .|| |
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekag.ngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
CYHAALEYLG
..| || |
vheavlegll
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1244-1338 | 6.9e-23 | 75.9 | In-house | 49-157 (350) | alignment | ||
Range on Protein: 1244-1338
Range on HMM: 49-157/350.0
PKNRYANVIAYDHSRVILS----P----MEGLPGSDYTNANYCDGY---RKQN---AYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQ
|||| |.. |.||||.| . | ..|| |||| ..| |||||.|| .|. ||.... . . |...|.. | |. ||..
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPTRDQEK
||. . ..
YWqegsydd
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1533-1770 | 1.2e-22 | 75.0 | In-house | 43-280 (312) | alignment | ||
Range on Protein: 1533-1770
Range on HMM: 43-280/312.0
F--KNRLLNIQPYEGNRVCLQpirGVEgSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPA-------E
| || ||| .. | | | | || | . . . ...||||| .|. ||.. || |..|. . | | ||| .| |
fkdlnrypniqcwdrgrftla...gde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdle
RSARYQYFVVD-PMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgqegPISVHCSAGVGRTGVFITLSVV
| .. . . . | .|| || . ..|.. ||..|.| | . .. |.| | |. |||||||||| .. . .
dhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk......pviahcsagvgrtgtlaliesm
LERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYLGSFD
. .|. .. .. .|| .| |.. || .. .. ||.| |
iaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskg
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1290-1468 | 2.9e-22 | 73.5 | In-house | 96-281 (302) | alignment | ||
Range on Protein: 1290-1468
Range on HMM: 96-281/302.0
TQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTLL--D-TTELATYTVRS-FAL-------VKNRSMEKREVKQFQF
| .|. .| .. . .. .| .... | . || .|. .. ... | . |. . |.|. .| . | | | .. |. |. ..|
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
TAWPDHGVPEHATSVLAFIsrvKSCNPPDaGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIH
.|||||| |..| . | . | |. ..|||||||||||. . | .. ...|. |. |. .|. | ||.|.| |..
sawpdhGapkeaytaldil...kfcesyk.knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyll
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1532-1622 | 1.2e-21 | 71.8 | In-house | 48-152 (350) | alignment | ||
Range on Protein: 1532-1622
Range on HMM: 48-152/350.0
KFKNRLLNIQPYEGNRVCLQ----P----IRGVEGSDYINASHIDGY----RQRNA--YIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCH
||| || ||| .|| |. . ....|||||... .. |||||.|| .| .||.... . . ..|..|... |...|||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
QYWPA
.||.
rYWqe
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1411-1477 | 2.3e-20 | 66.8 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 1411-1477
Range on HMM: 1-67/69.0
IVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVAS
.|||||.| ||||..| | . ||| || |||. | .| | || | .|||||.|| ||.
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealkl
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1214-1475 | 3.1e-20 | 67.0 | In-house | 19-279 (303) | alignment | ||
Range on Protein: 1214-1475
Range on HMM: 19-279/303.0
NDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSpmeglpGSDYTNANYCDGYRKQNAyIATQGPLLETMADFWRMVWEQRTNTI
.|| . .|.| . . . .. .| |||...|| |||.| || | | |.| . ...| | || || | ||||.|. ||. . .
edaniavnefekvvsylppsvsknqfvknmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcv
VMMTKLEERNRVKCDQYWPTR-DQEKY--GFIQVTLLDTTELATYTVRSFALVKNRSMeKREVKQFQFTAWPDHGVPEH-ATSVLAFISRVKSC--NPPD
... | ... | .| | |. .|.| . ||. | | | . | .. .. ||| .| . . .. | ...| . |
lllltdseydklggdsvfprnqdflkfeersirvgefkrvelgdgwvlkvlsvsngdy.ksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysd
AGPIVVHCSAGVGRTGAYIVIDSMLERIKHE-KTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
. | | .|.||.|.. .... .. | ..|. . .| | . || |. ... | | |
stptvymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1503-1765 | 8e-20 | 65.4 | In-house | 25-284 (302) | alignment | ||
Range on Protein: 1503-1765
Range on HMM: 25-284/302.0
ITGMENEFKRLASQKAQPSRfvSANIPANKFKNRLLNIQPYEGNRVCLQpirgVEGSDYINASHIDGYRQRNAYIATQGPLAETT---EDFWRMLWEQNS
. ...|||.....|.. . .| ||. ... .. |.| |. | .|.|||... .. | .| | ... |.|||| ....
taevkkefkkidtmkvdlek..Ckafkknlkknqsedvpildsnlvkle....aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqeki
TIIVMLSKLREMGReKCHQYWP--AERSARYQYFVVDPMSEYNMPQYIlREFKVTDARDGQSRTI--RQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ
. .|.| . |. . ....| .. |. . | .. . .. . .| | .. .| |... ||.. | . .|.. |..
vsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkik
fgQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
. .. . |.|| |.|.|| |..|.. . . . ..|| .|.|||..|.. .|| . | |.| |
..adentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyiallly
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1412-1478 | 1.4e-19 | 64.2 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 1412-1478
Range on HMM: 1-67/69.0
VVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAVASG
|||||.| ||||..| | . ||| || |||. | .| | || |..|.|||.|| ||. |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
fn3 | Fibronectin type III domain | 444-532 | 1.8e-18 | 59.7 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 444-532
Range on HMM: 2-85/85.0
PPQEVSGTVLSSTSIEVRWSPPPleDQNGDITGYKIIYRKMSLVStnnPEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPS
.|. .| . .|||....||||. |..|.||||.. ||... . .. .. |... .|..|. |. .| | .|| |... | ||.|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge...ewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1574-1766 | 1.1e-17 | 59.0 | In-house | 35-221 (255) | alignment | ||
Range on Protein: 1574-1766
Range on HMM: 35-221/255.0
NAYIAtqgplaeTTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARD--GQSRTIRQFQFTDWP
| |. | . |.... .... .|||. . | |.|||..|.| |. . .. |. . .. . .|| ..| . .|.. .... |.
nlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWi
EQGVPKSGEGFIDFIGQVHKTKeqfgqegPISVHCSAGVGRTGVFITLSVVLERM----R--YEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
|. |. . . |...| .. ||||.|.||. |. .| .| . . .| . .. || .|.. ..| | |. |..
eknaPelareilnilkvvrdsk.......svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldl
L
.
v
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1688-1764 | 4.2e-17 | 56.9 | In-house | 217-293 (297) | alignment | ||
Range on Protein: 1688-1764
Range on HMM: 217-293/297.0
QVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
|. . . .. .. |||||||||.|| . |.|...| . | |. ...|| ||. .||| .|....|.|.|.
qleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1239-1470 | 7.3e-17 | 56.4 | In-house | 16-254 (290) | alignment | ||
Range on Protein: 1239-1470
Range on HMM: 16-254/290.0
LETNKPKNRYANVIAyDHSRVILSPMEGLPGSDYTNANYCDgYRKQNAYIATQGPLLET-------MADFWRMVWEQRTNTIVMMTKLEERNRV----KC
.. .. ..|... .. ..||.| .|| ||. . . . |.|| |. .. . .|| |. . . . .||. . ||... |
vkkhemdqRlevpLv.eatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaC
DQYWPTRDQEKYGFIQVTL--LDTTELATYTVRSFaLVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKsCNppdAGPIVVHCSAGVGRTGAY
.| |.. |. | .|. . . .| .|| |. |. .. | . |.|. ..|. |. || .. |..||| |. | |
akYvpesvgeelkfkgltvkCkskekeddvetRel.vvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk.as...ktpvivHcvdGiSrsAal
IVIDSMLERIK-HEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEA
|. | .. | . . || ||. ........ |. .
aaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdag
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1198-1292 | 1.5e-16 | 54.4 | In-house | 4-95 (95) | alignment | ||
Range on Protein: 1198-1292
Range on HMM: 4-95/95.0
PIPVSQFQEHIERLKGNDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEglpGSDYTNANYCDGYRKQNAYIATQG
|| || |. |. .. | | .|. || .. |.| ||||. |.. || .||.|. ||| || . ||| ..|.|||.||
pihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlttkr...dsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1662-1765 | 2.1e-16 | 54.6 | In-house | 217-343 (350) | alignment | ||
Range on Protein: 1662-1765
Range on HMM: 217-343/350.0
IRQFQFTDWPEQGVPKSGEGFIDFIG--------QVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLE-RMR-------------YEGIVD-MFQTV
. |.|. |.. .. | .. . . .. . . || |||||||||||...|| .|. . | ....|
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv
KMLRTQRPAMVQTEDQYQFCYHAALEY
. || || |||. ||. |.|.|.| |
nelrkqrismvqnldqfifiYeallfy
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1240-1471 | 2.3e-16 | 54.1 | In-house | 49-281 (302) | alignment | ||
Range on Protein: 1240-1471
Range on HMM: 49-281/302.0
ETNKPKNRYANVIAYDHSRVILSPMEglpgSDYTNANYCDGYRKQNAYIATQGPLLETM---ADFWRMVWEQRTNTIVMMTKLEERNRvKCDQYWP--TR
| ||. .| ..|. .|.|. . .| || . .. | .| | ... ..|||||.... ..|.. . || .. ....| .
kknlkknqsedvpildsnlvkleaep....dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksg
DQEKYGFIQVTLL--DTTELATyTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSML
| ..|| . | . .| .. | . .. . . .. .| |... ||.. ... . . | . . ..|. |.|| || .. .
dykeygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavav
ERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEAL
|.....| . | |. .|.|| .|.. .||.... ||
eklqkgkepnikeivksiRsqRpravdslkQyvslyial
|
|||||||||
fn3 | Fibronectin type III domain | 747-829 | 2.4e-16 | 52.8 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 747-829
Range on HMM: 2-85/85.0
SPMNVTASPLSSSSISVSWDPPLeeERNGLILKYTIRYYSSAM---PTELTNRTTETDIVLTSLVPNTAYSVEVRAHTSVGPGPYS
.| |...|. .|.|...||.|| ...| | .|...| .. ..| |. |.| .|| | |.| |...|.|.. .| ||.|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1580-1756 | 2.8e-16 | 53.8 | In-house | 97-278 (302) | alignment | ||
Range on Protein: 1580-1756
Range on HMM: 97-278/302.0
QGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSA--RYQYFVVDPMS-EYNMPQYI--------LREFKVTDARDGQSRTIRQFQFT
| .|.| .| .. . | .|.| |... | . .|| .|. . ... . | .| . .. .. |.| . .. . .|. ..|.
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafs
DWPEQGVPKSGEGFIDFIgqvhKTKEQFGQEgpISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQ
||. | || . .| . | | . .. . ||||||||||| .... .. . . |. . |. .|. | ||.|.|
awpdhGapkeaytaldil....kfcesykkn..vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqli
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1407-1473 | 8.5e-16 | 52.5 | In-house | 246-313 (319) | alignment | ||
Range on Protein: 1407-1473
Range on HMM: 246-313/319.0
DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHE-KTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
. ||.||||| |||||| | | ...... ..||| | .| .| |.| ||| ||. |.|
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlse
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1704-1765 | 1.1e-15 | 51.7 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 1704-1765
Range on HMM: 2-63/69.0
VHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||.| |||| ||.. | . |.. | .||.| |. .| || || |..| | . | |
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1368-1472 | 1.4e-15 | 51.8 | In-house | 212-341 (350) | alignment | ||
Range on Protein: 1368-1472
Range on HMM: 212-341/350.0
MEKREVKQFQFTAWPDHGVPEHATSVLAFIS-------RV---KSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLE------RI----KH----EKTVD-
. .| |.|. |.| .. . |.| . . . . ||.||||||||||| .. .||.|. . .. || |
sdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl
IYGHVTCLRAQRNYMVQTEEQYIFIHEALY
| | || || |||. .|.|||.|||
isiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1703-1765 | 1.4e-15 | 51.4 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 1703-1765
Range on HMM: 2-64/69.0
SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||.| |||| ||.. | . |.. | .||.| |. .| || || | .| | . | |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1517-1623 | 1.5e-15 | 51.5 | In-house | 82-181 (244) | alignment | ||
Range on Protein: 1517-1623
Range on HMM: 82-181/244.0
KAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpiRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREmgrekC
. .|| . | | | .||| |.. ||| | .| | ||||| . . || || |||.|. |||.|. |. ..|.| . |
rpdpsvmkdafnpnnswknregaglpfdfnrvpls..kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee.....e
HQYWPAE
.|||
deywpds
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1698-1765 | 1.5e-15 | 51.7 | In-house | 246-314 (319) | alignment | ||
Range on Protein: 1698-1765
Range on HMM: 246-314/319.0
QEGPISVHCSAGVGRTGVFITLSVVLERMRYE-GIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
. ||. |||| ||||||. |. . .... ||. |.| .| .| |.| .||.| |. . ||
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1543-1760 | 4.1e-15 | 50.7 | In-house | 30-253 (290) | alignment | ||
Range on Protein: 1543-1760
Range on HMM: 30-253/290.0
YEGNRVCLQPIRGVEGSDYINASHIDgYRQRNAYIATQGPLAET-------TEDFWRMLWEQNSTIIVMLSKLREMGRE----KCHQYWPAERS--ARYQ
| .|| |. .||| |... . . . |.|| |.... |.|| | . ... .||| . | .. | .| | . ...
veatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk
YFVVDPMSEYNMPQYILREFKVTdARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKtkeqfgQEGPISVHCSAGVGRTGVFITLSVVLERMR-Y
. | | . . . || |. |.. |. .. .| . |... ... | .|.. .. |. ||| |. | .. .. . .
gltvkCkskekeddvetRelvvk.fddeeeftvtHsllkgWnklnvqedtktllsliqkvka......sktpvivHcvdGiSrsAalaaiilgyQkiaet
EGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYH
.| | . . .|.|| || ..... .. |
sgsvkledvlkalrkqralaitsalelafvda
|
|||||||||
I-set | Immunoglobulin I-set domain | 70-148 | 4.3e-15 | 47.3 | Pfam-A | 1-82 (90) | alignment | ||
Range on Protein: 70-148
Range on HMM: 1-82/90.0
PEITSNPrRYMVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRISMTDSG----LQFSRAQLSDQGRYECAAKNSLGTR
|..| . . ..|. . ... | ..|.|||.. |.|. ... ..|...| .. | .|... ||.|.|.| |.||.|..
pkftqkl.kdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagka
|
|||||||||
fn3 | Fibronectin type III domain | 547-636 | 4.3e-15 | 48.8 | Pfam-A | 2-84 (85) | alignment | ||
Range on Protein: 547-636
Range on HMM: 2-84/85.0
PPRKVRVRVHNSTTIRVQWQAPDpdLQNGEIRGYRIDYQTVTEEGdpvgsPQVLFINQPDLRVAVLSDLLPKTFYSIEIAAFTVRGDGIR
.|. ..|. .||.....|..|. ..|.| ||...|....... . . | . .. . ..|..| | | |.....| . | | .
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge.....ewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1572-1765 | 6.8e-15 | 49.7 | In-house | 36-226 (263) | alignment | ||
Range on Protein: 1572-1765
Range on HMM: 36-226/263.0
QRNAYIAtqgpLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARD--GQSRTIRQFQFTD
..| |. | .| . |.... .... .|||. | |.||| .|.| |. . .. |. . . . .|. ... . . .|.......
rknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykg
WPEQGVPKSGEGFIDFIGQVHKTKEqfgqegpISVHCSAGVGRTGVFITLSVVLERM----R--YEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAAL
|.|. |. . . . . . |. . ||||.|.||. | .| .| . . .| . .. || .|.. ..| | | |
Wiekndpelareilnilkvarnsks.......lvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvL
EY
..
df
|
|||||||||
fn3 | Fibronectin type III domain | 253-335 | 3.7e-14 | 45.8 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 253-335
Range on HMM: 2-85/85.0
VPNSPVVTGYTSSSLTVEWSTLS--SDTVTSHVLEYKRSRSGGSFTEMEIPSPQDtSFTIEGLLPYTEYAVRLLAVNSIGRSNPS
| . |.. ||.|||..|| . ....|. .||. ...|. .| .|.... |.|..|| |.||| .|. ||| | . .|
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1241-1333 | 6e-14 | 46.2 | In-house | 33-124 (332) | alignment | ||
Range on Protein: 1241-1333
Range on HMM: 33-124/332.0
TNKPKNRYANVIAYDHSRVILSPMEGlpGSDYTNANYCDGYRKQNAYIATQGPLLE-TMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPT
| || . ..||||| |.| .| |. ||.. ||| |..||| .| |. . | ||||| |.. . |... ..|... |.
nnmdmnriphlycfdhsrvelapqdg..kddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrkapydisd
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1506-1581 | 7.7e-14 | 45.7 | In-house | 25-95 (95) | alignment | ||
Range on Protein: 1506-1581
Range on HMM: 25-95/95.0
MENEFKRLASQKAQPsrFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRgveGSDYINASHIDGYRQRNAYIATQG
..|||| .. | . || |||.||| ||. ||.| | |||||| .||| ..|.|||.||
fdnefksismtsgap..ytvgsseanipknrflnifpydatrvvlttkr...dsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1248-1400 | 9.2e-14 | 45.6 | In-house | 57-207 (332) | alignment | ||
Range on Protein: 1248-1400
Range on HMM: 57-207/332.0
YANVIAYDHSRVILSPMEgLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP--TRDQEKYGFIQVT
... ||. | |.. | | || . . || | . . . ||.|| ||.. .||.. . | . | |.|.| ||.. |.|...|.
vvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildve
LLDTTELATYTVRSFALVKnrSMEKREVKQFQFTAWPDHGVPEHaTSVLAFISRV
. . . . .| . | | | .|. ... | . .| ||. .
rkefvkrniletrllelsk..GnethrvlhykvfGwtettlpky.edflalrkvm
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1520-1763 | 3.4e-13 | 43.9 | In-house | 36-276 (303) | alignment | ||
Range on Protein: 1520-1763
Range on HMM: 36-276/303.0
PSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpirgveGSDYINASHIDGYRQRNAyIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQY
| . .. | |||. .. . .| | | || ||... ...| | || ||. |. |||.|. ||. ...| |. . .
ppsvsknqfvknmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggdsv
WPAERSA-RY--QYFVVDPMSEYNMPQyiLREFKVTDARDGQSRT-IRQFQFTDWPEQGVPKSG-EGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTG
.| .. .. .. | . . .. . .|| .|. .. . .. .|| . .| | |. | |. .. . | .|.||.|
fprnqdflkfeersirvgefkrvelgd..gwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgrag
VFITLSVVLERMRY-EGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAAL
| . . . .|. . ....| | || |. . |
tfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytlla
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1529-1687 | 4.5e-13 | 43.3 | In-house | 49-205 (332) | alignment | ||
Range on Protein: 1529-1687
Range on HMM: 49-205/332.0
PANKFKNRLLNIQPYEGNRVCLQPIRgVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARY
.. . ...| ||. . | | . . . ||||| .. . || | . . ||.|. ||.| ||.| . |.. || .|.| . .
rleavnrnvvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreel
QYFVVDPMS-EYnMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSgEGFIDFIG
.. ..| |. . . ||. .. . .. . ... | | .|| | |. .
kfGildverkef.vkrniletrllelskGnethrvlhykvfGwtettlpky.edflalrk
|
|||||||||
fn3 | Fibronectin type III domain | 348-429 | 5.7e-13 | 42.0 | Pfam-A | 1-85 (85) | alignment | ||
Range on Protein: 348-429
Range on HMM: 1-85/85.0
SQPEQFEGVAISASQIRLTWMMR-DTEPQIIRYELYYNVS-TNDNDMHKTITPTT-DYVLDNLRPNTLYHIRLAARSETGEGASS
|.||.. ........|.| | . .| .||. | . ... . ..|...|| ..| .|.|.| |..|..|... ||| .|
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1406-1473 | 6.4e-13 | 43.2 | In-house | 226-293 (297) | alignment | ||
Range on Protein: 1406-1473
Range on HMM: 226-293/297.0
PDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
| ...|||||||||.| . | .|....... |. .. || || .||| ||. ....| .
prnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
JmjC | JmjC domain, hydroxylase | 1-32 | 6.6e-13 | 36.4 | Pfam-A | 83-114 (114) | alignment | ||
Range on Protein: 1-32
Range on HMM: 83-114/114.0
ITQEQGEFMVTFPFGYHSGFNHGYNCAESTNF
..|..|||...|| .|||.||.|.|.||..||
fvqkpgefVfvfpgayHsvfnlgfniaeavnf
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1244-1350 | 7.9e-13 | 42.4 | In-house | 50-169 (349) | alignment | ||
Range on Protein: 1244-1350
Range on HMM: 50-169/349.0
PKNRYANVIAYDHSRVILSP--------------MEGLPGSDYTNANYCDGY--RKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKC
|||| ... |.||||.| .. || |||| .. ||||| || |. ||.... .. . .. ... .| . ||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
DQYWptrDQEKYGFIQVTLLDTT
|.|| .. .| |.| | ..
diyw...qelsysnitvklqnss
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1279-1335 | 1e-12 | 42.1 | In-house | 230-283 (440) | alignment | ||
Range on Protein: 1279-1335
Range on HMM: 230-283/440.0
DGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERnrvKCDQYWPTRD
.|| |.||.|||| || |. ||||.| . | ||.|. .|... | |||
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvnt
|
|||||||||
fn3 | Fibronectin type III domain | 652-731 | 8e-12 | 38.3 | Pfam-A | 3-83 (85) | alignment | ||
Range on Protein: 652-731
Range on HMM: 3-83/85.0
PVAFRVENNLDDTYTATWSPPVETHGDLVTYRLSYGPE-SGR-PLYLDLRPSEFqSYTFDDLRLGTRYEFKLTASNEEGNSN
| ..|... ... | .|||| . .|... |.. | .. .|. . .. ... |.|. .|. ||.|||...| |..|..
PenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngagegp
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1567-1647 | 1.5e-11 | 38.3 | In-house | 229-307 (440) | alignment | ||
Range on Protein: 1567-1647
Range on HMM: 229-307/440.0
IDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREmgrEKCHQYWPAE-RSARYQYFVVDPMSEYNMPQYILR
..|| ..||.|||| || | ||||.. . . . |.|| .| . | ||| . || . | | || . .|
fegyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfgpftvghkgsenmnrvkvr
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1197-1280 | 3.3e-11 | 37.2 | In-house | 4-85 (440) | alignment | ||
Range on Protein: 1197-1280
Range on HMM: 4-85/440.0
PPIPVSQFQEHIERLKgnDAMLFSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDG
|| |..| .... . . | .|. . | . | ..| || |||| |..|||||||.| ..|.| ||| || | .|
rpiivadfadyvqnnr..rsrafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1266-1386 | 5e-11 | 37.0 | In-house | 9-126 (130) | alignment | ||
Range on Protein: 1266-1386
Range on HMM: 9-126/130.0
GLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERnrvkcDQYWPTRDQEKYG--FIQVTLLDTTELATytVRSFALV
|.| .| ||.. . . |. || || .| |||.|. |. | .|.. .|| |.||| . .. | ||| | | ... |
rlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdrdefkn..ikasnle
KNRSMEK--REVKQFQFTAWPDHGV
.. . . . . || . || |
iesdlneshqaltmfqisnwpsdgt
|
|||||||||
I-set | Immunoglobulin I-set domain | 164-247 | 5.7e-11 | 34.1 | Pfam-A | 1-90 (90) | alignment | ||
Range on Protein: 164-247
Range on HMM: 1-90/90.0
PRFTILPENQEVVPGGSVNLTCAAYGSPMPRVRWMKAGMDLDDMDDLPIGRNV----LQLRDIY--ESANYTCVATSLLGTIDTSARVTV
|.||. ....|| | ||.|.| . |.| |.|.|.| | .| ... . . | .... .. .|||.|| .|. ..|...|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1694-1766 | 7.2e-11 | 36.0 | In-house | 260-344 (349) | alignment | ||
Range on Protein: 1694-1766
Range on HMM: 260-344/349.0
EQFGQEGPISVHCSAGVGRTGVFITLSVVLE----------RMRYEGIV-D-MFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
. | .. |||||| |||||..|| ..|. .. .. . | .. .| || || .||| |. ..|.| |.|.
ldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyf
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1285-1386 | 1.7e-10 | 34.9 | In-house | 137-235 (244) | alignment | ||
Range on Protein: 1285-1386
Range on HMM: 137-235/244.0
NAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERnrvkcDQYWPTRDQ-EKYG-FIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWP
|| || || .| |||.|. |. | .|.. .|| |.||| . | | | ||| | |. . . . .. . || . ||
aeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdseplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwp
DHGV
|
sdgt
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1532-1615 | 2.3e-10 | 34.5 | In-house | 35-117 (332) | alignment | ||
Range on Protein: 1532-1615
Range on HMM: 35-117/332.0
KFKNRLLNIQPYEGNRVCLQPIRGVEgsDYINASHIDGYRQRNAYIATQGPLAETTED-FWRMLWEQNSTIIVMLSKLREMGREK
||. . .. .|| | | | . |. ||| .||| ...||| .| |. . || ||||. |.. ..|... . | . |
mdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1555-1675 | 4.2e-10 | 34.0 | In-house | 9-126 (130) | alignment | ||
Range on Protein: 1555-1675
Range on HMM: 9-126/130.0
GVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREmgrekCHQYWPAERSAR-YQYFVVDPMSEYNMPQYILREF-KVT
..| .||||| . . . |. || |||.|. |||.|. |. ..|.| . | .||| |. .. ... . ..| .. ..
rlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsvee.....edeywpdsePlewyeediivtltdrdefknikasnleie
DARDGQSRTIRQFQFTDWPEQGV
. ... || ..|| .|
sdlneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1506-1570 | 7.1e-10 | 32.8 | In-house | 24-86 (440) | alignment | ||
Range on Protein: 1506-1570
Range on HMM: 24-86/440.0
MENEFKRLASQKAQPSRFvsANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGY
.|.|. | | .||| |..| || ||| || |. .|| |. ..|| |||||||.|.|
fedewsllpsglsqpsdi..aslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1689-1759 | 7.9e-10 | 33.5 | In-house | 104-169 (182) | alignment | ||
Range on Protein: 1689-1759
Range on HMM: 104-169/182.0
VHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVlermrYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCY
. | .. ||| ..||| || ||||| |. .| | .. ...|..| .|| .|| .| ...
ivkvvafalqegkvavhChaGlGrtGvliacylv.....yakrltaekaiklvrskrpksiqtreqvelvk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1533-1621 | 1.1e-09 | 32.1 | In-house | 50-154 (349) | alignment | ||
Range on Protein: 1533-1621
Range on HMM: 50-154/349.0
FKNRLLNIQPYEGNRVCL----QPIRGVEGS----------DYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKC
||| .| ||| || | .. .... | ||||| .. . ||||| || | .||.... .. ... |.. | . |||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
HQYWP
..||
diywq
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1372-1472 | 1.5e-09 | 31.6 | In-house | 219-341 (349) | alignment | ||
Range on Protein: 1372-1472
Range on HMM: 219-341/349.0
EVKQFQFTAWPDHGVPEHATSVLAFISrVKS-----------CNPPDAGPIVVHCSAGVGRTGAYIVIDSMLE----------RIKH-EKTVD-IYGHVT
|. |.|. |.| .. |.| . ||. . . ...|||||| |||| .. .|..|. .|| .. | |. |
ellqlqvknwldlslllnPisilqale.vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivn
CLRAQRNYMVQTEEQYIFIHEALY
|| || ||| |.|.|.|||
elrkqrismvqnlaqfiaiyealL
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1519-1604 | 1.9e-09 | 31.5 | In-house | 25-115 (347) | alignment | ||
Range on Protein: 1519-1604
Range on HMM: 25-115/347.0
QPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEG-----SDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
||.| |.. . ||| . . . || | | . . ||||||| .. || || || .| |||.|. . | .|
spskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
Ig_3 | Immunoglobulin domain | 70-143 | 2e-09 | 29.5 | Pfam-A | 2-75 (75) | alignment | ||
Range on Protein: 70-143
Range on HMM: 2-75/75.0
PEITSNPRRYMVVENNrpATIYCGATGNP-EPEILWF-KEFVPIEANDRISMTDSGLQFSRAQLSDQGRYECAAKN
|.|...|. ..... | |. | |.|.| .| | | .. .. ... | ..| | .| .. .| | |.| |.|
Pvisvspsptvtsggn..vtLtCsaeggpppptisWyietppelqgsegssssestLtissvtsedsGtYtCvasN
|
|||||||||
Ig_2 | Immunoglobulin domain | 70-146 | 4.2e-09 | 28.3 | Pfam-A | 2-69 (80) | alignment | ||
Range on Protein: 70-146
Range on HMM: 2-69/80.0
PEITSNPrryMVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRIsmtdsgLQFSRAQLSDQGRYECAAKNSLG
| ....| ||. . . |. | |.|||.|.. | |. .... . .. | . ....|.|.|.| |.|| |
pvlsapp...tvvtegenvtLtCqapgnptpkvqwykdgeelsqsqna......lfipnvsaedsGtYtCrasnseg
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1237-1316 | 8.4e-09 | 29.4 | In-house | 32-116 (347) | alignment | ||
Range on Protein: 1237-1316
Range on HMM: 32-116/347.0
SNLETNKPKNRYANVIAYDHSRVILSPMEGL-----PGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMM
.. | . ||| .| | .||.||| . . | || . .. || || || .|. |||.|| . .| .
vewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
Ig_2 | Immunoglobulin domain | 170-247 | 1e-08 | 27.1 | Pfam-A | 6-80 (80) | alignment | ||
Range on Protein: 170-247
Range on HMM: 6-80/80.0
PENQEVVPGGSVNLTCAAYGSPMPRVRWMKAGMDLDdmddlpIGRN--VLQLRDIYESANYTCVATS-LLGTIDTSARVTV
.....| | .|.|||.| | | |.| | | | |. ..| ... .| .|||.|. ... .| .|||
apptvvtegenvtLtCqapgnptpkvqwykdgeels......qsqnalfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1670-1759 | 1.6e-08 | 29.9 | In-house | 85-170 (194) | alignment | ||
Range on Protein: 1670-1759
Range on HMM: 85-170/194.0
W--PEQGVPKSGEGFIDFIGQVHKTKEQfGQEGPISVHCSAGVGRTGVFITLSVVLermrYEGIvDMFQTVKMLRTQRPAMVQTEDQYQFCY
. |..|.. | | .|. |.. .. ..| . ||| ||.||||... . . |. .. . ....| || .... |... .
lpfpddgtvPsleillrfldlvdeflne.dpggvvaVHCkaGlgRtGtlvaaYLiy....rlgm.saeeAialfrekRpgaipnqdyleall
|
|||||||||
Ig_3 | Immunoglobulin domain | 167-234 | 1.2e-07 | 23.8 | Pfam-A | 5-75 (75) | alignment | ||
Range on Protein: 167-234
Range on HMM: 5-75/75.0
TILPENQEVVPGGsVNLTCAAYGSP-MPRVRWM-KAGMDLDDMDDLPIGRNVLQLR--DIYESANYTCVATS
.. |.. ... |. |.||| | |.| |...|. . .. |. ... .. ..| .. . | .|||||..
svspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtissvtsedsGtYtCvasN
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1367-1469 | 1.2e-07 | 26.3 | In-house | 77-170 (182) | alignment | ||
Range on Protein: 1367-1469
Range on HMM: 77-170/182.0
SMEKREVKQFQFtAWPDHGVPEhATSVLAFISRVKSCNppDAGPIVVHCSAGVGRTGAYIVIDSMlerikHEKTVDIYGHVTCLRAQRNYMVQTEEQYIF
.. .... ..| .|.|.||. ...| . |... . | . ||| || |||| | . . | .. .. .|..| .|| || .
almeqgiyvynf.gwkDygvas.leriLdivkvvafal..qegkvavhChaGlGrtGvliacylv.....yakrltaekaiklvrskrpksiqtreqvel
IHE
..|
vke
|
|||||||||
fn3 | Fibronectin type III domain | 843-932 | 1.9e-07 | 24.3 | Pfam-A | 1-85 (85) | alignment | ||
Range on Protein: 843-932
Range on HMM: 1-85/85.0
SAPLDLRCAAPHGTQLEVKWSHPSniQRSGPGYNYLVYSTNSADNTdvS-TWGRpVSAGEFtKLELRGLQEETTYYVAVKLDTPEGNSPLS
||| .|.. . |.|...||.|. ...|| .| | .. .. .. . |.. . ..|.||.. |.| . |. . .|..| |
saPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge..ewkeft.vprttt.svtltgLkpgteYefrVqavngagegpeS
|
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subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1237-1335 | 3.4e-07 | 23.3 | In-house | 22-88 (169) | alignment | ||
Range on Protein: 1237-1335
Range on HMM: 22-88/169.0
SNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNAnycdgyrkqnayiatqgplletmadfwRMVWEQRTNTIVMMTKLEERNrvkcdQYWPTRD
..| .|. ||| | .| | || | . |||| || ||.|| . ||.. ...| ..|| ..
aeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddkn.....nfwpeke
|
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0038934 | (Phosphotyrosine protein) phosphatases II | 1379-1427 | 3.4e-07 | 25.6 | In-house | 85-134 (194) | alignment | ||
Range on Protein: 1379-1427
Range on HMM: 85-134/194.0
TAWPDHGVPEHATSVLAFISRVKSCNPPD-AGPIVVHCSAGVGRTGAYIV
.||.|.. .| |.. |. . | | ..||| ||.|||| ..
lpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva
|
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subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1237-1335 | 4e-07 | 23.0 | In-house | 21-87 (169) | alignment | ||
Range on Protein: 1237-1335
Range on HMM: 21-87/169.0
SNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNAnycdgyrkqnayiatqgplletmadfwRMVWEQRTNTIVMMTKLEERNrvkcdQYWPTRD
..| .|. ||| | .| | || | . |||| || ||.|| . ||.. ...| ..|| ..
aeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddkn.....nfwpeke
|
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subfamily_eak_pd | Subfamily eak | 1403-1475 | 5.1e-07 | 23.4 | In-house | 232-305 (332) | alignment | ||
Range on Protein: 1403-1475
Range on HMM: 232-305/332.0
CNPPDAGPIVvHCSAGVGRTGAYIVIDSMLERIKHEKT--VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
|| ||. .. | |.|...||| ... | |. . . . .|.. | .. |. ||.|.. . .
htppsfapii.qsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
|
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subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1231-1282 | 6.5e-07 | 23.2 | In-house | 28-78 (244) | alignment | ||
Range on Protein: 1231-1282
Range on HMM: 28-78/244.0
QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEgLPGSDYTNANYCDGYR
.| . | .| |||| |.. .|..||||| . |||| |||| .| .
eflqtnavlsanatknryinilpfdetrvilsssk.kegsdyinanyiqgsq
|
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fn3 | Fibronectin type III domain | 946-1038 | 1.2e-06 | 21.7 | Pfam-A | 2-84 (85) | alignment | ||
Range on Protein: 946-1038
Range on HMM: 2-84/85.0
EPRSFDAHIASDNTINLVWSEPSDIPGRLKDYVIKYHTSDDFRreypdyydggGEIEILASEQRVSLSGQLFKPNMEYEFNITARTEAIRGPP
.|. . .. ......| ||.|.| | .. | ..| .... . . |. .... |. . ||..||||...|...| ||.
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekggge..........ewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
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subfamily_CDC14_pd | Subfamily CDC14 | 1699-1760 | 1.2e-06 | 22.6 | In-house | 263-318 (328) | alignment | ||
Range on Protein: 1699-1760
Range on HMM: 263-318/328.0
EGPISVHCSAGVGRTGVFITLSVVlERMRyegiVDMFQTVKMLRTQRPAMVQTEdQYQFCYH
|| |.||| ||.|||| .|. .. .. | . ... || || .| . | .|...
eGaiavhCkaGLGrtGtLiacylm.khyr....ftaaeaiawlricrPGsvigp.qqkflee
|
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subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1525-1624 | 1.3e-06 | 21.4 | In-house | 21-88 (169) | alignment | ||
Range on Protein: 1525-1624
Range on HMM: 21-88/169.0
SANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINAshidgyrqrnayiatqgplaettedfwRMLWEQNSTIIVMLSKLremgrEKCHQYWPAER
|.. .|. ||| || || . ||||||| ||.|| |...||.| . ..||
maeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdt.....ddknnfwpeke
|
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subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1525-1623 | 1.9e-06 | 20.8 | In-house | 20-86 (169) | alignment | ||
Range on Protein: 1525-1623
Range on HMM: 20-86/169.0
SANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINAshidgyrqrnayiatqgplaettedfwRMLWEQNSTIIVMLSKLremgrEKCHQYWPAE
|.. .|. ||| || || . ||||||| ||.|| |...||.| . ..||
maeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdt.....ddknnfwpek
|
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subfamily_PRL_pd | Subfamily PRL | 1690-1737 | 1.9e-06 | 22.0 | In-house | 81-128 (151) | alignment | ||
Range on Protein: 1690-1737
Range on HMM: 81-128/151.0
HKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQT
|.| . . ..||| ||.||. |...|... . |.|| |.. ..
lkekfkeepkstvavhcvaGlGraPvlvalalieaGmkyedavefire
|
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PTPc_motif_SM00404 | 1655-1751 | 2.9e-06 | 22.2 | In-house | 42-127 (140) | alignment | |||
Range on Protein: 1655-1751
Range on HMM: 42-127/140.0
RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVhktkeqFGQEGPISVHCSAGVGRTGVFItlsvVLERMRYEGIvDMFQTVKMLRTQRPAMVQT
. ....| | . | .. . | . .||| .. ..| . ||| ||| |.. .| . . |||... .. . ..... .||.. ..
kensgfqilqiplddnekdklskyldkvldfiena......ekkggkvlVHCqaGvSRSatli....iaYlmryrql.slaeayefvkerRpiispn
|
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PTEN_1 | 1326-1423 | 4e-06 | 21.8 | In-house | 42-145 (196) | alignment | |||
Range on Protein: 1326-1423
Range on HMM: 42-145/196.0
KcdQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKN---RSMEKREVKQFQFT----AWPDHGVPEHAtSVLAFISRVKSCNP--PDAGPIVVHCS
. ...... .. . ... | . | ..| .... .. || ...| .. ... ..|||.| . ...... ..... |. . ..|||
q..eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapsls.elfdicksfiewllsdpngnvVlVHCk
AGVGRTG
||.||.|
aGlgRsG
|
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subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1327-1483 | 4.4e-06 | 20.4 | In-house | 150-309 (332) | alignment | ||
Range on Protein: 1327-1483
Range on HMM: 150-309/332.0
CDQYWPTRDQeKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDH-GVPEHATSVLAFIS--RVKSCN--PPDAGPIVVHCSAGVGR
| ..|| . | | ... . . . ...| | . .. ..| | | .||. . | | ..| . |||.. |..|| .
crkfwpekrs.kkdfpalsiqasddhsethmktfnltvtekkqdhqtvlmhfyewadasklpeymldmrasiklqyirsskktgvcigpimlvcatgvek
TGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEaVASGTTEVH
. || .. || |. | . ..... || ..| | | | . .| | ||
caisatidiivsriteehrvgfketmsaikmqrfgcfrtvgpystacemlmk.favttgvvh
|
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ig | Immunoglobulin domain | 88-140 | 9.6e-06 | 16.9 | Pfam-A | 4-63 (64) | alignment | ||
Range on Protein: 88-140
Range on HMM: 4-63/64.0
ATIYCGA-TGNPEPEILWFKEFVPIEANDRISMTDSG------LQFSRAQLSDQGRYECA
.|. | . .|.|.... |.|| . | .... .. . |...... .| | |.|
vtLtCsvssgppstdvsWykegkgleesqktgvvenrvsaqevLtinnvtkedsGtYtCv
|