Gene SYNJ in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP121_AA protein Get Run
SpurP121_AA_183-484 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Synaptojanin_pd Subfamily Synaptojanin 55-805 0.0 1354.7 In-house 1-753 (754) alignment
Range on Protein: 55-805
Range on HMM: 1-753/754.0
QKMTDAYGCLGALRLSVGDESLLYLVLVTGCSSVGKVQESEIFRITSTLFISLRNNSSDEDRITEVRKLLNSGTFYFSWSASTTTRFDLSLCAQRQKQDH
||..||||.||.|||..|||.| .|||||||.||||....|||.|||| ..|||...||||||.|..|||.|||||||.||....|.||||.|||.||..
qkivdaygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrseasdedriielkkllasgtfyfsssadsasrldlslsaqrrkqee

VSDNRFFWNRSLHLHLQRFDVNCSDWLLKTMCGGVEVRTVYCGTRQAKACIVSRLSCERAGTRFNVRGTNDDGHVANFCETEQVIFLDNKVTSFIQTRGS
..|||||||||||||||||.|||.|||||.|||.||.||||.|..||||...||||||||||||||||.||.|.||||.||||||.||.|||||.|.|||
sednrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirGs

VPLFWEQPGINVGVHKVKMSRGFEASAPAFDRHLTMVKAHYGDQVIVNLLGSKEGEDMLSKSFQNHLKASSHDQDTPHILFDYHQMCR-GKVDNLPLLKK
|||||||||..|| ||||.||||||||.||||||...|..||..||||||||||||..|||.|..|||||.|..|.|.. |||||... || ..|  |.|
vPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnllGskegeevlskafkkhlkasehakdvpfvkfdyhqkvkggkkeklekllk

KVATE-MDQFGFFFSEGGEVIRQQTGTIRSNCLDCLDRTNAVQTFFGQDMLAKQLEALGVSSKPQIMSRFLETYKTIWGLSGDHISRIYAGTGALEGKTK
|.... .....||.|.|.|| ..|||..|.||||||||||||||..|...|.||||||..|||....||| |..|..|  .||.||.|||||||||||.|
kqlklflesasfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealklsskesvvsrfeevfkslWsknGdeiskiyaGtgalegkak

AGKLRDGARSVTRTIQNNFFDGTKQESIDVLLLGSSLVGSLANKASSLLPSSHLHASPDILQGVCEREGDFTSSSRFRICVGTWNVNGGKNSHNIAFKNE
..||.||||||.|||||||.|..|||.||.||||...|..||.||..||.||.|.||..||. ..||| ..|.....|||||||||||||. ...|.|||
vsklkdgarsvartiqnnfldsskqeaidllllgntyveeladkarallkssllrasakilkelvereqelteakklricvgtwnvnggkqlrsvalkne

SLTDWLLDNPQITGVDYSVPNDIYAIGFEEMVDLNAGNIISASTTNQRKWGVELQKSLSRDHKYVLLVCEQLVGVCLYIFIRPQHAPFIRDVAVDTVKTG
||||||||.|...|...| |.|||||||||.|||||.|..||||||...|..||||.||||.|||||..||||||||..|.||...||||||||.|||||
sltdwlldlpelsgaedskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvlsrdakyvlltseqlvGvclfvfvrpklvpfirdvavstvktG

LKGAAGNKGGVAIRFVFHGTSMCFVCAHLAAGQSHIKDRNDDYAEISSKIMFPMGRSLESHDYVFWCGDFNYRIDKDNDEVKDLVAIHDYEALKECDQLL
|.|||||||.||||...|.||.||.|.|||||||..|.||.|||||..||.|||||.|||||||||.||||||||...||||.||. .||..|.|.||| 
lgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkkkdydklvendqlt

LERRKGNTFQGFAEGTIRFAPTYKYDLFSEDYDTSEKMRTPAWTDRILWRRHK
 ...||..|.|||||...|||||||||||.|||||||.|.||||||.||||.|
kqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwrrkk

subfamily_INPP5F_pd Subfamily INPP5F 109-804 3e-186 612.3 In-house 117-804 (951) alignment
Range on Protein: 109-804
Range on HMM: 117-804/951.0
NNSSDEDR-ITEVRKLLNSGTFYFSWSASTTTRFDLSLCAQRQKQDHVSDNRFFWNRSLHLHLQRFDVNCS-DWLLKTMCGGVEVRTVYCGTRQAKACIV
...  |.| . |..|||..|.||.| .   |  .      ..... .. |.|||||. |   |   . . .  .|.  . | ||.....    ...  ..
eeeklekrlleelkkllsdgsFYysldfDltntlqkrgleeksestddwderFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltli

SRLSCERAGTRFNVRGTNDDGHVANFCETEQVIFLDNKVTSFIQTRGSVPLFWEQPGINVGvHKVKMSRGFEASAPAFDRHLTMVKAHYGDQVIVNLLGS
|| | .||||||. || .|||.||||.|||...   ..| ||.| |||||.||||.|  .   |.|. | .|.. ||||.|..    .|| .||||||  
srrSrkragtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvfweqsgkkyk.pkikitrseeetqpaFdehfkeqlkkygkvvivnllsq

KEGEDMLSKSFQNHLKASShDQDTPHILFDYHQMCRG-KVDNLPLLKKKVATEMDQFGFFFSEGGE-VIRQQTGTIRSNCLDCLDRTNAVQTFFGQDMLA
|. |  |||.....|.... ..|.  | ||.|. ..| |..|.  | ...  |. ..|.|. .  | || .|.| .| |||||||||| ||.  .. .| 
kssekklskaykeqllkle.skdvflikfdfheetsgekfenvsklielikneikevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqaiskavle

KQLEALGVSSKPQIMS--RFLETYKTIWGLSGDHISRIYAGTGALEGK-TKA------GKLRDGARSVTRTIQNNFFDGTKQESIDVlllgssLVGSLAN
 ||| ||. .  . .   ..|...|..|   || |||.|||| || |. |.       | | ||  ||.|  .||| |  .|. ||.      | | | .
lqleklglfepessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidl......llGklpk

KASSLLPSSHLH-----AspdilqgvCEREGDFTSSSRFRICVGTWNVNGgkNShniafKNESLTDWLLDNPQitgvdySVPNDIYAIGFEEMVDLNAGN
.  . |   . .               |.|  ||. |   . ||. ||||  .|     |.. |  .| .  .          |.. .| .|.|.| ||.
qevvelidpkkeekeeel........rekeekftetsninllvgsvnvng..ss.....kkadlskllfpige......kfkpDlvvlGLqEvvELtaGs

IISASTTNQRKWGVELQKSL---SRDHKYVLLVCEQLVGVCLYIFIRPQHAPFIRDVAVDTVKTGLKGAAGNKGGVAIRFVFHGTSMCFVCAHLAAGQSH
|..| .. .. |   ... |   ||..||..|  |||... | .|.| ..|  ...| .||.|||..| |||||.||.|| .  || ||| .|||||.| 
iLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfeysatsFcfvnsHlaAGasn

IKDRNDDYAEISSKIMFPMGRSLESHDYVFWCGDFNYRIDKDNDEVKDLVAIHDYEALKECDQLLLERRKGNTFQGFAEGTIRFAPTYKYDLFSEDYDTS
. .| .|| || ..| |. .. .. ||..|| ||.|||||  |.||.  .  .... | | |||  |  .|. |.|| | |..| ||||||| ...||||
veeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqeidkLleyDqLtkeieaGevFegfkEetlkFrPtYkyDlgtknYDts

EKMRTPAWTDRILWRRH
||.|||||||||... .
ekeRtPaWtDRiiykge

Sac_COG5329 48-803 2.7e-136 447.2 In-house 50-817 (1070) alignment
Range on Protein: 48-803
Range on HMM: 50-817/1070.0
ESLRKQYQKmTDAYGCLGALrlsvGDESLLYLVLVTGCSSV-GKVQESEIFRITSTLFISLRNNSSDEDRI--------T--------EVRKLLNSGTFY
| .|..  .    ||.|| .      | .|.| ..|| |.| . ... .|..|    ||||.||. |. .|        .        | .|||  |.||
egfrslssa.heiygvlGli....elegslflivitgkskvaqvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFY

FSWSASTTTRFDLSLCAQRQKQDHVSDNRFFWNRSLHL----HLQRFDVNCS------DWLLKTMCGGVEVRTVYCGTRQAKACIVSRLSCERAGTRFNV
||   . |...  .|  . . ..  .|..|.||. |      . .. ... .      ..|    .| .|   .. . ...   ..||.| .||||||. 
fStdfditntLqkrlkeelelsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRfla

RGTNDDGHVANFCETEQVIFLDNKVTSFIQTRGSVPLFWEQPGINVGVHKVKMSRGFEASAPAFDRHLTMVKAHYGDQVIVNLLGSKEGEDMLSKSFQNH
|| .|||.|||| ||||..   ....||.|.|||.|.|||| . .    |.. .| .||. .|||.| .     |||..|||||. |. | .||. ...|
rGvDddGnvanFVETEqIvyssqycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekh

LKaSSHDQDTPHILFDYHQMCR-GKVDNLPLLKKKVATEMDQFGFFF--SEGGEVIRQQTGTIRSNCLDCLDRTNAVQTFFGQDMLAKQLEALGVSSKPQ
||  | . ..  . ||.|. ..  . |....| .... .. .||.|.   . |..| .|.| .|.||||||||||..|.  .. .| .|.. ..|.|. .
lk.lsekpkihlteFdfhketsqdgfddvkkLlplieqdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaid

IMsRFLETYKTIWGLSGDHISRIYAGTGALEGK-------TKAGKLRDGARSVTRTIQNNFFDGTKQESIDVLLlgsslvGSLANKASSLLPSSHLHASP
    ||. ....|   || ||.|| ||||| ..       . ||.|.|   ||.| ..|||.|. ||..||.||      | | .. .. |  .     .
de.dflqklneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllL......gklpdqeavelydpineyvn

DILQgvcEREGDFTSSSRFRICVGTWNVNGgknshniAFKNESLTDWLLDNPQITGVdySVPNDIYAIGFEEMVDLNAGNIISASTTNQRKWGVELQKSL
  |.   ..|  || .. . | ..| |.||        .....|...||.  ..     .. ... .. ...   | . .....| . .. . . ..|  
lrlr...kseseftaaknvsiftltfnsng.......essstkllklllkvlekkis..klvvgvvglqkqiwlelillssltksefkeeeeenlvrkye

SR-DHKYVLLVCEQLVGVCLYIFIRPQHAPFIRDVAVDTVKTGLKGAAGNKGGVAIRFVFHGTSMCFVCAHLAAGQSHIKDRNDDYAEISSKIMFPMGRS
.. . |...   .|| .. .  ... . .     . . . ||| .| ..||| |.|..   |....|| |..|...  ...|| .|  |.... ....  
nklkkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaeseglvfifvdasaaledenesernskyesitkrvskeipkm

LESHDYVFWCGDFNYRIDKDNDEVKDLVAIHDYEALKECDQLLLERRKGNTFQGFAEGTIRFAPTYkYDLFSEDYDTSEKMRTPAWTDRILWRR
 . |.  .. ...|..|| |..||.. .  .... ||. |.   .. | .... . ...  ..... ..     ....|. ... .|...  . 
ikdhqlilldiainltidydeeevraekekeidrelkkydtkqeltekvfvekvleptevpellek.ksyeddndtdtedayrklrtrkliqke

subfamily_SAC1_pd Subfamily SAC1 57-487 3.6e-102 333.4 In-house 4-452 (458) alignment
Range on Protein: 57-487
Range on HMM: 4-452/458.0
MTDAYGCLGALRLSVGDesllYLVLVTGCSSVGKVQESEIFRITSTLFISLRNNSS---------DEDRITEVRKLLNSGTFYFSWSASTTTRFDLSLC-
... .|.|| ..|  |.    ||...|  ..||... . |.|.. .  |.. .||          ..  .. ....|.| |||||     |. ..     
vvkiagilGiikLlsgk....ylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekv

----AQRQKQDHVSDNRFFWNRSLHLHLQRfDVNCSDWLLKTMCGGVEVRTVYCGTRQAKACIVSRLSCERAGTRFNVRGTNDDGHVANFCETEQVIFLD
     ....  .. |.|||||. |  .|.. . . ....|  . | ......   ... |  ..|| |. |||||..||| . .|.|||| ||||.. ..
tsaalkerslleradeRffwnkhlledlrk.epelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveae

NKVTSFIQTRGSVPLFWEQPGiNVGV-HKVKMSrGFEASAPAFDRHLTMVKAHYGDQVIVNLLGSKEGEDMLSKSFQNhLKASSHDQDTPHILFDYHQMC
...|||.|.|||.||.|.| . |.    |||.|   | |  ||..||   ...||..|.|||.  |  |  | ..... .  ....... .. ||.|. |
kaltsFvqvRGsiPllWsqkp.nLkykPkvkls.esedsldafkkhldeqielygenvlvnLvdqkGsEkklgeayes.vvralnkkkikyvafDFHkeC

RG-KVDNLPLLKKKVATEMDQFGFFFS-EGGEVIRQQTGTIRSNCLDCLDRTNAVQTFFGQDMLAKQLEALGV---SSKPQIMSRFLETYKTIWGLSGDH
|  . | | ||......|..|.|.|.  | ......|.| .|.||.||||||| ||. .....| |||| |||    || .  .......| .|   .|.
rkmrwdrlklLidqlekelsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnada

ISRIYAGTGALEG-------KTKAGKLRDGARSVTRTIQNNFFDGTKQESIDVLlLGS
.|  |||||||         .|. | ||||  ||.| ..||| ||..|.|||.. ||.
vsvqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLf.lgk

Syja_N SacI homology domain 60-344 2.3e-81 264.4 Pfam-A 1-315 (319) alignment
Range on Protein: 60-344
Range on HMM: 1-315/319.0
AYGCLGALRLSVgdesLLYLVLVTGCSSVGKVQ-ESEIFRITSTLFISLRNNSSD---------------EDRITEVRKLLNSGTFYFSWSastttrFDL
|||.|| .||.       ||...|....|.|.. | .|..|.|. ||.|......               |. .....|||.||.|||| .      .||
aygilGlirlls....esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSyd......yDl

SLCAQRQKQDH---------------VSDNRFFWNRSLHLHLQRFDVNCSDWLLKTMCGGVEVRTVYCG-TRQAKACIVSRLSCERAGTRFNVRGTNDDG
. ..||. ...                 |.||.||| |. .|.......|.|||  ..| || |....   .... ...|| |..|||||.. ||..|||
trslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddG

HVANFCETEQVIF-L-D--NKVTSFIQTRGSVPLFWEQ-PGINvGVHKVKMSRGFEASAPAFDRHLTMVKAHYGDQVIVNLLGSKEGEDMLSKSFQNHLK
.||||.||||...   .  ..|.||.|.|||||||||| ....   .|.|..|  ||| .||..|.. .. .||..|.||||..|..| .||. ......
nvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelin

AS----SHDQDTPHILFDYHQMCRGK
.     .....  .| ||.|. |.||
klnkklkekkklkyiefDfhkeckgk

Syja_N SacI homology domain 60-344 2.3e-81 264.4 In-house 1-315 (319) alignment
Range on Protein: 60-344
Range on HMM: 1-315/319.0
AYGCLGALRLSVgdesLLYLVLVTGCSSVGKVQ-ESEIFRITSTLFISLRNNSSD---------------EDRITEVRKLLNSGTFYFSWSastttrFDL
|||.|| .||.       ||...|....|.|.. | .|..|.|. ||.|......               |. .....|||.||.|||| .      .||
aygilGlirlls....esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSyd......yDl

SLCAQRQKQDH---------------VSDNRFFWNRSLHLHLQRFDVNCSDWLLKTMCGGVEVRTVYCG-TRQAKACIVSRLSCERAGTRFNVRGTNDDG
. ..||. ...                 |.||.||| |. .|.......|.|||  ..| || |....   .... ...|| |..|||||.. ||..|||
trslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddG

HVANFCETEQVIF-L-D--NKVTSFIQTRGSVPLFWEQ-PGINvGVHKVKMSRGFEASAPAFDRHLTMVKAHYGDQVIVNLLGSKEGEDMLSKSFQNHLK
.||||.||||...   .  ..|.||.|.|||||||||| ....   .|.|..|  ||| .||..|.. .. .||..|.||||..|..| .||. ......
nvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelin

AS----SHDQDTPHILFDYHQMCRGK
.     .....  .| ||.|. |.||
klnkklkekkklkyiefDfhkeckgk

subfamily_FIG4_pd Subfamily FIG4 47-484 1.6e-59 192.7 In-house 57-538 (569) alignment
Range on Protein: 47-484
Range on HMM: 57-538/569.0
TESLRKQYQKMTDAYGCLGALRLSVGdeslLYLVLVTGCSSVGKVQESEIFRITSTLFISLRNNS------SDEDRITEVRKLLN-SGTFYFSWSASTTT
 |. |. ..| . ||| || .|.  |     ||.|||  ..|... .  |..|  . .|.. ..|      |||.| ... | .. . .||||.|   | 
eeanrdglekkvsayGilGfvrfleg....yylilvtkrkkvaviGghaiykiedialikitedskksekssdearylklfkdvdltknfyfsysydltr

RFDLSLC---AQRQK---QD----------HVSDNRFFWNRSLHLHLQRfDVNCSDWLLKTMCGGVEVRTVYCGTRQAKACIVSRLSCERAGTRFNVRGT
 .   |     .|.|   .|            ....| ||  |   |.   |.  ||||. . | |.  ..   ... . ....| | . ||.||  || 
tlqtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkd.tvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGv

NDDGHVANFCETEQVI-------FLDNKVTSFIQTRGSVPLFWEQPGINVGVH-KVKMsRGFEASAPAFDRHLTMVKAHYGDQV-IVNLLGSKE---GED
| .|.|||  ||||..       . .....||.|.||||||.|.|   ..    ..|.    .  | |  .|.  .  .||  . |.||. .||    | 
nnkGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpiki.dvvdPfasaaalhfddlfqryGspiiilnlvkkkekrkres

MLSKSFQNHLKAS----SHDQDTPHILFDYHQMCRGKV-DNLPLLKKKVATEMDQFGFFFSEGG-EVIRQQTGTIRSNCLDCLDRTNAVQTFFGQDMLAK
.|.. |.. ..       ...   .| .| ... . |  . |  |.|   . . . |.|.|.   |  . |.| .|.||.|||||||| |   |.  |. 
illeefeaaieylneflPeekklkyiswdmaraskskeenvlevlekyaeksvkktGiflsapdlestkiqeGivrtnCvdcldrtnaaqfvigkvalgy

QLEALGVSSKPQI--MSRFLETYKTIWGLSGDHISRIYAGTG---ALEGKTK----AGKLRDGARSVTRTIQNNFFDGTKQESIDVLL
||..||.  ....   |   .  . ..   || ..  |.|.     ..  .|    . | ||  ....| . | | |  ||..|...|
qlkslGiidesklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlfl

Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 534-850 1.5e-30 96.8 Pfam-A 1-249 (249) alignment
Range on Protein: 534-850
Range on HMM: 1-249/249.0
GTWNVNGGKNSHNIAFKNESLTDWLLDNPqitgvdysvpNDIYAigFEEMVDLnagniiSASTTNQRKWGVELQ-----KSLSRDHKYVllvceqlVGVC
.||||.|... .. | |.. | |.| ..            |...  . |...         | ... ... ||      || ......        .| .
ltwNvlgwnarsdrakkldqladllqsed..........pDvll..LQEvded......plsellatglaselgldgdgksggggggda.......gggg

LYIFIRPQHAPFIRDVAVDTVKTGLK---GAAGNKGGVAIRFVfhGTSMCFVCAHLAAGQSHIK--DRnDDYAEIsSKIMFPMGRSleshdYVFWCGDFN
| .. .  ..  ||.. ....|.|     .  ||||.|..||   |.....|..||..|..  .   |  ..||| .|.. . . |     .|...||||
lallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaei.dkladdsrgs.....pvilaGDfN

YRIDKDNdevkdlvaihdyealkecdqlllerrkgntfQGFAEGTIRFAPTYKYDLFSEDY-------------DTSEKMRTPAWTDRILW-RRHKPFYF
.|.| ..                               .|| |. . |.|....| .. ..             ||.|| |.||..|.||. .... .. 
srpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilvssgwpalvv

KQTSDSKELSSqigntnlviynwdsgrvlhygraelktSDH
...|  .. ..                           |||
sgasllsdrgg...........................SDH

DUF1866 Domain of unknown function (DUF1866) 858-923 2.2e-15 45.6 Pfam-A 1-67 (146) alignment
Range on Protein: 858-923
Range on HMM: 1-67/146.0
EVEVQLVDEDTRESIFHDVFCQQGPPDATVILSLTDPHGNQ-VVFADDEMDAVLDLTASEGEAILVR
.||.. ||.. |...|..|  .|||||||...||...  ..  .| .. ....|.  || || ||||
dveilevdpearravfkeviaaqGPpDativvslksgdedekeifdealieeLlqelaslGeviLvR

subfamily_INPP5F_pd Subfamily INPP5F 825-879 3.3e-08 23.1 In-house 796-851 (951) alignment
Range on Protein: 825-879
Range on HMM: 796-851/951.0
TNLVIYNWDSGRVLH-YGRAELKTSDHRPVVAIIEVEVQLVDEDTRESIFHDVFCQ
|. .||. .  . |. | .||.. |||||| |.  ..|. |||. . .. . .. .
tDRiiykgevledLeyysdaeilisDHrPvyaafrakvtvvDekkkltLkkklyee