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• Phosphatase Subfamily PTPN1
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN1|Subfamily PTPN1]] The PTPN1 subfamily dephoshorylates kinases of various families, including Insulin receptor kin
  3 KB (337 words) - 16:06, 22 June 2015
• Phosphatase Subfamily PTPRA
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRA|Subfamily PTPRA]] PTPRA is a deuterostome-specific receptor PTP subfamily.
  4 KB (553 words) - 18:53, 22 December 2016
• Phosphatase Subfamily PTPRC
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRC|Subfamily PTPRC]] PTPRC has twin intracellular PTP phosphatase domains, and extracellular FN3 domains, plus a CD45-specific and a PTP-N-te
  1 KB (201 words) - 23:40, 13 April 2017
• Phosphatase Family PTP
  [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfam ...amilies. This subfamily is known as High Molecular Weight Protein Tyrosine Phosphatase (HMWPTP) in the [http://scop.berkeley.edu/sunid=52805 SCOP database]. Compa
  10 KB (1,429 words) - 17:35, 4 May 2018
• Phosphatases and Diseases
  Table of phosphatase disease associations, taken from our 2017 phosphatome publication <cite>Che | Gene Symbol || Entrez Gene ID || Fold || Family || Subfamily || Hamosh et al. (2005) - OMIM || Landrum et al. (2014) - ClinVar || Yip et
  14 KB (1,612 words) - 16:05, 13 April 2017
• Phosphatase Subfamily Ptp69D
  ...]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_Ptp69D|Subfamily Ptp69D]] ...st in vertebrates, though the vertebrate PTPRA family is highly similar in phosphatase domain sequence to PTP69D.
  1 KB (161 words) - 16:41, 29 May 2015
• Phosphatase Subfamily PTPRG
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRG|Subfamily PTPRG]] The phosphatase activity is modulated by the ligands binding to extracellular region <cite>
  2 KB (334 words) - 05:52, 2 April 2017
• Phosphatase Subfamily PTPN14
  ...1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN14|Subfamily PTPN14]] PTPN14 is a cytoskeleton-associated phosphatase involved in cell migration and adhesion, EGFR signaling and regulation of t
  4 KB (519 words) - 02:46, 7 September 2016
• Phosphatase Gene PTPN1
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN1|Subfamily PTPN1]]: [[Phosphatase_Gene_PTPN1|Gene PTPN1]] See evolution section on page of [[Phosphatase_Subfamily_PTPN1|Subfamily PTPN1]].
  993 B (123 words) - 21:16, 17 December 2014
• Phosphatase Subfamily PTPMT1
  ...1]]: [[Phosphatase_Family_DSP|Family DSP]]: [[Phosphatase_Subfamily_PTPMT1|Subfamily PTPMT1]] PTPMT1 has a single domain: phosphatase domain. It has a mitochondria-targeting sequence on N-terminus.
  2 KB (246 words) - 05:12, 27 February 2015
• Phosphatase Subfamily PTPN23
  ...1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN23|Subfamily PTPN23]] (HD-PTP) ...in. Fungi also have a likely ortholog (Bro1 in S. cerevisiae) that lacks a phosphatase domain, but retains the BRO1 and ALIX_LYPXL_bnd domains.
  8 KB (975 words) - 07:59, 24 July 2017
• Phosphatase Subfamily PTPRD
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRD|Subfamily PTPRD]] All three human PTPRDs have twin intracellular PTP phosphatase domains, and extracellular Ig domains and FN3 domains. Each of them have mu
  7 KB (966 words) - 21:42, 21 December 2016
• Pseudophosphatases (obsolete)
  ==== Second phosphatase domains of receptor PTPs ==== ...city, and dimerization <cite>denHertog02, Barr09</cite>. Because the first phosphatase domains are active, these receptor PTPs are active at protein level. These
  6 KB (818 words) - 00:36, 14 April 2017
• Phosphatase Subfamily PTPN12
  ...1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN12|Subfamily PTPN12]] ...in-containing proteins. The region of 301-320 in PTPN22 interacts with its phosphatase domain and reduces its catalytic activity <cite>Liu09</cite>.
  19 KB (2,489 words) - 03:16, 16 May 2016
• Phosphatase Subfamily PTPRK
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRK|Subfamily PTPRK]] PTPRK is a chordate-specific subfamily that regulates cell-cell adhesion. It is involved in human cancer and in th
  9 KB (1,280 words) - 02:30, 10 November 2016
• Phosphatase Subfamily PTPRB
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRB|Subfamily PTPRB]] PTPRB (aka R3) is a metazoan-specific subfamily of receptor PTPs, with diverse functions.
  16 KB (2,151 words) - 23:52, 4 April 2017
• Phosphatase Subfamily PTPRN
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPRC|Subfamily PTPRN]] PTPRN is a receptor lipid phosphatase family involved in secretion in neuronal and endocrine tissues, including i
  6 KB (885 words) - 17:24, 2 April 2017
• Pseudophosphatases
  ...atase_Subfamily_CDC14|CDC14]] subfamily, where CDC14A and CDC14B have dual phosphatase domains, with the first being a pseudophosphatase. ... |STYXL1]], and a single member of the [[Phosphatase_Subfamily_DSP3|DSP3]] subfamily, DUSP27.
  5 KB (688 words) - 00:38, 14 April 2017
• Phosphatase Subfamily PTPN3
  ...C1]]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN3|Subfamily PTPN3]] The PTPN3 subfamily emerged in holozoa and duplicated in vertebrates. Human has two members, PT
  4 KB (562 words) - 08:12, 26 July 2017
• Phosphatase Subfamily PTPN5 RR
  ...]: [[Phosphatase_Family_PTP|Family PTP]]: [[Phosphatase_Subfamily_PTPN5_RR|Subfamily PTPN5_RR]] PTPN5_RR is a tyrosine-specific phosphatase subfamily that regulates ERK signaling. Uniquely, some members are non-receptors, whi
  13 KB (1,701 words) - 04:23, 3 April 2017