Difference between revisions of "Phosphatase Superfamily HAD"
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The HAD (HaloAcid Dehalogenase) superfamily contains an array of different hydrolase enzymes, including several that are known to have protein phosphatase or other phosphatase activites <cite>Koonin, Burroughs</cite>. The following HAD families have reported protein phosphatase activity: | The HAD (HaloAcid Dehalogenase) superfamily contains an array of different hydrolase enzymes, including several that are known to have protein phosphatase or other phosphatase activites <cite>Koonin, Burroughs</cite>. The following HAD families have reported protein phosphatase activity: | ||
− | [[Phosphatase_Family_EYA|EYA]] (Eyes Absent) | + | ===== [[Phosphatase_Family_EYA|EYA]] (Eyes Absent) ===== |
− | [[Phosphatase_Family_FCP|FCP]] | + | ===== [[Phosphatase_Family_FCP|FCP]] ===== |
− | [[Phosphatase_Family_NagD|NagD]] | + | ===== [[Phosphatase_Family_NagD|NagD]] ===== |
− | [[Phosphatase_Family_MDP1|MDP1]] | + | ===== [[Phosphatase_Family_MDP1|MDP1]] ===== |
== References == | == References == |
Revision as of 04:15, 29 May 2014
Phosphatase Classification: HAD
The HAD (HaloAcid Dehalogenase) superfamily contains an array of different hydrolase enzymes, including several that are known to have protein phosphatase or other phosphatase activites [1, 2]. The following HAD families have reported protein phosphatase activity:
Contents
EYA (Eyes Absent)
FCP
NagD
MDP1
References
- Koonin EV and Tatusov RL. Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approach to database search. J Mol Biol. 1994 Nov 18;244(1):125-32. DOI:10.1006/jmbi.1994.1711 |
- Burroughs AM, Allen KN, Dunaway-Mariano D, and Aravind L. Evolutionary genomics of the HAD superfamily: understanding the structural adaptations and catalytic diversity in a superfamily of phosphoesterases and allied enzymes. J Mol Biol. 2006 Sep 1;361(5):1003-34. DOI:10.1016/j.jmb.2006.06.049 |